diff --git a/media/libaom/moz.build b/media/libaom/moz.build
index db3f9ca6eca4c..3ffbba38914c7 100644
--- a/media/libaom/moz.build
+++ b/media/libaom/moz.build
@@ -9,6 +9,10 @@ with Files('*'):
 
 include('sources.mozbuild')
 
+if CONFIG["CPU_ARCH"] == "aarch64":
+    if CONFIG['OS_TARGET'] == 'Darwin':
+        NO_PGO = True
+
 # Linux, Mac and Win share file lists for x86* but not configurations.
 if CONFIG['CPU_ARCH'] == 'x86_64':
     EXPORTS.aom += files['X64_EXPORTS']
@@ -25,10 +29,12 @@ if CONFIG['CPU_ARCH'] == 'x86_64':
         ASFLAGS += [ '-I%s/media/libaom/config/mac/x64/' % TOPSRCDIR ]
         LOCAL_INCLUDES += [ '/media/libaom/config/mac/x64/' ]
         EXPORTS.aom += [ 'config/mac/x64/config/aom_config.h' ]
+        NO_PGO = True
     else: # Android, Linux, BSDs, etc.
         ASFLAGS += [ '-I%s/media/libaom/config/linux/x64/' % TOPSRCDIR ]
         LOCAL_INCLUDES += [ '/media/libaom/config/linux/x64/' ]
         EXPORTS.aom += [ 'config/linux/x64/config/aom_config.h' ]
+        NO_PGO = True
 elif CONFIG['CPU_ARCH'] == 'x86':
     EXPORTS.aom += files['IA32_EXPORTS']
     SOURCES += files['IA32_SOURCES']