diff --git a/migrations/versions/2024_05_28_1846-415a8f855e14_multi_colors.py b/migrations/versions/2024_05_28_1846-415a8f855e14_multi_colors.py
new file mode 100644
index 000000000..30c1dbc7a
--- /dev/null
+++ b/migrations/versions/2024_05_28_1846-415a8f855e14_multi_colors.py
@@ -0,0 +1,31 @@
+"""multi_colors.
+
+Revision ID: 415a8f855e14
+Revises: 395d560284b3
+Create Date: 2024-05-28 18:46:12.935449
+"""
+
+import sqlalchemy as sa
+from alembic import op
+
+# revision identifiers, used by Alembic.
+revision = "415a8f855e14"
+down_revision = "395d560284b3"
+branch_labels = None
+depends_on = None
+
+
+def upgrade() -> None:
+    """Perform the upgrade."""
+    # ### commands auto generated by Alembic - please adjust! ###
+    op.add_column("filament", sa.Column("multi_color_hexes", sa.String(length=128), nullable=True))
+    op.add_column("filament", sa.Column("multi_color_direction", sa.String(length=16), nullable=True))
+    # ### end Alembic commands ###
+
+
+def downgrade() -> None:
+    """Perform the downgrade."""
+    # ### commands auto generated by Alembic - please adjust! ###
+    op.drop_column("filament", "multi_color_direction")
+    op.drop_column("filament", "multi_color_hexes")
+    # ### end Alembic commands ###
diff --git a/spoolman/api/v1/filament.py b/spoolman/api/v1/filament.py
index 555ae8453..43419ac0b 100644
--- a/spoolman/api/v1/filament.py
+++ b/spoolman/api/v1/filament.py
@@ -7,10 +7,10 @@
 from fastapi import APIRouter, Depends, Query, WebSocket, WebSocketDisconnect
 from fastapi.encoders import jsonable_encoder
 from fastapi.responses import JSONResponse
-from pydantic import BaseModel, Field, field_validator
+from pydantic import BaseModel, Field, field_validator, model_validator
 from sqlalchemy.ext.asyncio import AsyncSession
 
-from spoolman.api.v1.models import Filament, FilamentEvent, Message
+from spoolman.api.v1.models import Filament, FilamentEvent, Message, MultiColorDirection
 from spoolman.database import filament
 from spoolman.database.database import get_db_session
 from spoolman.database.utils import SortOrder
@@ -86,9 +86,26 @@ class FilamentParameters(BaseModel):
     )
     color_hex: Optional[str] = Field(
         None,
-        description="Hexadecimal color code of the filament, e.g. FF0000 for red. Supports alpha channel at the end.",
+        description=(
+            "Hexadecimal color code of the filament, e.g. FF0000 for red. Supports alpha channel at the end. "
+            "If it's a multi-color filament, the multi_color_hexes field is used instead."
+        ),
         examples=["FF0000"],
     )
+    multi_color_hexes: Optional[str] = Field(
+        None,
+        description=(
+            "Hexadecimal color code of the filament, e.g. FF0000 for red. Supports alpha channel at the end. "
+            "Specifying multiple colors separated by commas. "
+            "Also set the multi_color_direction field if you specify multiple colors."
+        ),
+        examples=["FF0000,00FF00,0000FF"],
+    )
+    multi_color_direction: Optional[MultiColorDirection] = Field(
+        None,
+        description=("Type of multi-color filament. Only set if the color_hex field contains multiple colors. "),
+        examples=["coaxial", "longitudinal"],
+    )
     external_id: Optional[str] = Field(
         None,
         max_length=256,
@@ -104,24 +121,58 @@ class FilamentParameters(BaseModel):
 
     @field_validator("color_hex")
     @classmethod
-    @classmethod
     def color_hex_validator(cls, v: Optional[str]) -> Optional[str]:  # noqa: ANN102
         """Validate the color_hex field."""
         if not v:
             return None
-        if v.startswith("#"):
-            v = v[1:]
-        v = v.upper()
 
-        for c in v:
+        clr = v.upper()
+        if clr.startswith("#"):
+            clr = clr[1:]
+
+        for c in clr:
             if c not in "0123456789ABCDEF":
                 raise ValueError("Invalid character in color code.")
 
-        if len(v) not in (6, 8):
+        if len(clr) not in (6, 8):
             raise ValueError("Color code must be 6 or 8 characters long.")
 
         return v
 
+    @field_validator("multi_color_hexes")
+    @classmethod
+    def multi_color_hexes_validator(cls, v: Optional[str]) -> Optional[str]:  # noqa: ANN102
+        """Validate the multi_color_hexes field."""
+        if not v:
+            return None
+        for clr_raw in v.split(","):
+            clr = clr_raw.upper()
+            if clr.startswith("#"):
+                clr = clr[1:]
+
+            for c in clr:
+                if c not in "0123456789ABCDEF":
+                    raise ValueError("Invalid character in color code.")
+
+            if len(clr) not in (6, 8):
+                raise ValueError("Color code must be 6 or 8 characters long.")
+
+        return v
+
+    @model_validator(mode="after")  # type: ignore[]
+    def validate(self) -> "FilamentParameters":
+        """Validate the model."""
+        if self.color_hex and self.multi_color_hexes:
+            raise ValueError("Cannot specify both color_hex and multi_color_hexes.")
+        if self.multi_color_hexes and len(self.multi_color_hexes.split(",")) < 2:  # noqa: PLR2004
+            raise ValueError("Must specify at least two colors in multi_color_hexes.")
+        if self.multi_color_hexes and not self.multi_color_direction:
+            raise ValueError("Multi-color filament must have multi_color_direction set.")
+        if not self.multi_color_hexes and self.multi_color_direction:
+            raise ValueError("Single-color filament must not have multi_color_direction set.")
+
+        return self
+
 
 class FilamentUpdateParameters(FilamentParameters):
     density: Optional[float] = Field(None, gt=0, description="The density of this filament in g/cm3.", examples=[1.24])
@@ -394,6 +445,8 @@ async def create(  # noqa: ANN201
         settings_extruder_temp=body.settings_extruder_temp,
         settings_bed_temp=body.settings_bed_temp,
         color_hex=body.color_hex,
+        multi_color_hexes=body.multi_color_hexes,
+        multi_color_direction=body.multi_color_direction,
         external_id=body.external_id,
         extra=body.extra,
     )
diff --git a/spoolman/api/v1/models.py b/spoolman/api/v1/models.py
index d1fa5baf1..8e56af032 100644
--- a/spoolman/api/v1/models.py
+++ b/spoolman/api/v1/models.py
@@ -93,6 +93,13 @@ def from_db(item: models.Vendor) -> "Vendor":
         )
 
 
+class MultiColorDirection(Enum):
+    """Enum for multi-color direction."""
+
+    COAXIAL = "coaxial"
+    LONGITUDINAL = "longitudinal"
+
+
 class Filament(BaseModel):
     id: int = Field(description="Unique internal ID of this filament type.")
     registered: SpoolmanDateTime = Field(description="When the filament was registered in the database. UTC Timezone.")
@@ -155,9 +162,27 @@ class Filament(BaseModel):
         None,
         min_length=6,
         max_length=8,
-        description="Hexadecimal color code of the filament, e.g. FF0000 for red. Supports alpha channel at the end.",
+        description=(
+            "Hexadecimal color code of the filament, e.g. FF0000 for red. Supports alpha channel at the end. "
+            "If it's a multi-color filament, the multi_color_hexes field is used instead."
+        ),
         examples=["FF0000"],
     )
+    multi_color_hexes: Optional[str] = Field(
+        None,
+        min_length=6,
+        description=(
+            "Hexadecimal color code of the filament, e.g. FF0000 for red. Supports alpha channel at the end. "
+            "Specifying multiple colors separated by commas. "
+            "Also set the multi_color_direction field if you specify multiple colors."
+        ),
+        examples=["FF0000,00FF00,0000FF"],
+    )
+    multi_color_direction: Optional[MultiColorDirection] = Field(
+        None,
+        description=("Type of multi-color filament. Only set if the multi_color_hexes field is set."),
+        examples=["coaxial", "longitudinal"],
+    )
     external_id: Optional[str] = Field(
         None,
         max_length=256,
@@ -192,6 +217,10 @@ def from_db(item: models.Filament) -> "Filament":
             settings_extruder_temp=item.settings_extruder_temp,
             settings_bed_temp=item.settings_bed_temp,
             color_hex=item.color_hex,
+            multi_color_hexes=item.multi_color_hexes,
+            multi_color_direction=(
+                MultiColorDirection(item.multi_color_direction) if item.multi_color_direction is not None else None
+            ),
             external_id=item.external_id,
             extra={field.key: field.value for field in item.extra},
         )
diff --git a/spoolman/database/filament.py b/spoolman/database/filament.py
index 21904e8d6..e4079624f 100644
--- a/spoolman/database/filament.py
+++ b/spoolman/database/filament.py
@@ -11,7 +11,7 @@
 from sqlalchemy.ext.asyncio import AsyncSession
 from sqlalchemy.orm import contains_eager, joinedload
 
-from spoolman.api.v1.models import EventType, Filament, FilamentEvent
+from spoolman.api.v1.models import EventType, Filament, FilamentEvent, MultiColorDirection
 from spoolman.database import models, vendor
 from spoolman.database.utils import (
     SortOrder,
@@ -42,6 +42,8 @@ async def create(
     settings_extruder_temp: Optional[int] = None,
     settings_bed_temp: Optional[int] = None,
     color_hex: Optional[str] = None,
+    multi_color_hexes: Optional[str] = None,
+    multi_color_direction: Optional[MultiColorDirection] = None,
     external_id: Optional[str] = None,
     extra: Optional[dict[str, str]] = None,
 ) -> models.Filament:
@@ -68,6 +70,8 @@ async def create(
         settings_extruder_temp=settings_extruder_temp,
         settings_bed_temp=settings_bed_temp,
         color_hex=color_hex,
+        multi_color_hexes=multi_color_hexes,
+        multi_color_direction=multi_color_direction.value if multi_color_direction is not None else None,
         external_id=external_id,
         extra=[models.FilamentField(key=k, value=v) for k, v in (extra or {}).items()],
     )
@@ -231,11 +235,18 @@ async def find_by_color(
 
     found_filaments: list[models.Filament] = []
     for filament in filaments:
-        if filament.color_hex is None:
+        if filament.color_hex is not None:
+            colors = [filament.color_hex]
+        elif filament.multi_color_hexes is not None:
+            colors = filament.multi_color_hexes.split(",")
+        else:
             continue
-        color_lab = rgb_to_lab(hex_to_rgb(filament.color_hex))
-        if delta_e(color_query_lab, color_lab) <= similarity_threshold:
-            found_filaments.append(filament)
+
+        for color in colors:
+            color_lab = rgb_to_lab(hex_to_rgb(color))
+            if delta_e(color_query_lab, color_lab) <= similarity_threshold:
+                found_filaments.append(filament)
+                break
 
     return found_filaments
 
diff --git a/spoolman/database/models.py b/spoolman/database/models.py
index c0dfe188a..992296983 100644
--- a/spoolman/database/models.py
+++ b/spoolman/database/models.py
@@ -49,6 +49,8 @@ class Filament(Base):
     settings_extruder_temp: Mapped[Optional[int]] = mapped_column(comment="Overridden extruder temperature.")
     settings_bed_temp: Mapped[Optional[int]] = mapped_column(comment="Overridden bed temperature.")
     color_hex: Mapped[Optional[str]] = mapped_column(String(8))
+    multi_color_hexes: Mapped[Optional[str]] = mapped_column(String(128))
+    multi_color_direction: Mapped[Optional[str]] = mapped_column(String(16))
     external_id: Mapped[Optional[str]] = mapped_column(String(256))
     extra: Mapped[list["FilamentField"]] = relationship(
         back_populates="filament",
diff --git a/tests_integration/tests/filament/test_add.py b/tests_integration/tests/filament/test_add.py
index 57cb1f7b9..b7efe31ac 100644
--- a/tests_integration/tests/filament/test_add.py
+++ b/tests_integration/tests/filament/test_add.py
@@ -128,3 +128,106 @@ def test_add_filament_color_hex_alpha():
 
     # Clean up
     httpx.delete(f"{URL}/api/v1/filament/{filament['id']}").raise_for_status()
+
+
+def test_add_filament_multi_color():
+    """Test adding a filament with multi color hexes."""
+    multi_color_hexes = "FF0000,00FF00"
+    multi_color_direction = "coaxial"
+
+    # Execute
+    result = httpx.post(
+        f"{URL}/api/v1/filament",
+        json={
+            "density": 1.25,
+            "diameter": 1.75,
+            "multi_color_hexes": multi_color_hexes,
+            "multi_color_direction": multi_color_direction,
+        },
+    )
+    result.raise_for_status()
+
+    # Verify
+    filament = result.json()
+    assert filament["multi_color_hexes"] == multi_color_hexes
+    assert filament["multi_color_direction"] == multi_color_direction
+
+    # Clean up
+    httpx.delete(f"{URL}/api/v1/filament/{filament['id']}").raise_for_status()
+
+
+def test_add_filament_multi_color_errors():
+    """Test adding a filament with multi color hexes with errors."""
+    # Bad hex color list
+    # Execute
+    result = httpx.post(
+        f"{URL}/api/v1/filament",
+        json={
+            "density": 1.25,
+            "diameter": 1.75,
+            "multi_color_hexes": "FF0000,",  # Bad 2nd color
+            "multi_color_direction": "coaxial",
+        },
+    )
+
+    # Verify
+    assert result.status_code == 422
+
+    # Missing multi_color_hexes but direction is specified
+    # Execute
+    result = httpx.post(
+        f"{URL}/api/v1/filament",
+        json={
+            "density": 1.25,
+            "diameter": 1.75,
+            "multi_color_direction": "coaxial",
+        },
+    )
+
+    # Verify
+    assert result.status_code == 422
+
+    # multi_color_hexes is specified but direction is not
+    # Execute
+    result = httpx.post(
+        f"{URL}/api/v1/filament",
+        json={
+            "density": 1.25,
+            "diameter": 1.75,
+            "multi_color_hexes": "FF0000,00FF00",
+        },
+    )
+
+    # Verify
+    assert result.status_code == 422
+
+    # multi_color_hexes only has a single color
+    # Execute
+    result = httpx.post(
+        f"{URL}/api/v1/filament",
+        json={
+            "density": 1.25,
+            "diameter": 1.75,
+            "multi_color_hexes": "FF0000",
+            "multi_color_direction": "coaxial",
+        },
+    )
+
+    # Verify
+    assert result.status_code == 422
+
+    # Both multi_color_hexes and color_hex is specified
+    # Execute
+    result = httpx.post(
+        f"{URL}/api/v1/filament",
+        json={
+            "density": 1.25,
+            "diameter": 1.75,
+            "color_hex": "FF0000",
+            "multi_color_hexes": "FF0000,00FF00",
+            "multi_color_direction": "coaxial",
+        },
+    )
+
+    # Verify
+    assert result.status_code == 422