diff --git a/src/main/java/uk/ac/ebi/eva/submission/controller/submissionws/SubmissionController.java b/src/main/java/uk/ac/ebi/eva/submission/controller/submissionws/SubmissionController.java
index 1331ca1..89d36b4 100644
--- a/src/main/java/uk/ac/ebi/eva/submission/controller/submissionws/SubmissionController.java
+++ b/src/main/java/uk/ac/ebi/eva/submission/controller/submissionws/SubmissionController.java
@@ -93,6 +93,14 @@ public ResponseEntity<?> markSubmissionUploaded(@RequestHeader("Authorization")
             return new ResponseEntity<>("Unauthorized", HttpStatus.UNAUTHORIZED);
         }
 
+        String submissionStatus = submissionService.getSubmissionStatus(submissionId);
+        if (! Objects.equals(submissionStatus, SubmissionStatus.OPEN.toString())){
+            return new ResponseEntity<>(
+                    "Submission " + submissionId + " is not in status " + SubmissionStatus.OPEN +
+                            ". It cannot be marked as " + SubmissionStatus.UPLOADED +
+                            ". Current Status: " + submissionStatus,
+                    HttpStatus.BAD_REQUEST);
+        }
         try {
             submissionService.checkMetadataFileInfoMatchesWithUploadedFiles(submissionAccount, submissionId, metadataJson);
             Submission submission = this.submissionService.uploadMetadataJsonAndMarkUploaded(submissionId, metadataJson);
diff --git a/src/test/java/uk/ac/ebi/eva/submission/integration/SubmissionWSIntegrationTest.java b/src/test/java/uk/ac/ebi/eva/submission/integration/SubmissionWSIntegrationTest.java
index 71d7f7a..364caad 100644
--- a/src/test/java/uk/ac/ebi/eva/submission/integration/SubmissionWSIntegrationTest.java
+++ b/src/test/java/uk/ac/ebi/eva/submission/integration/SubmissionWSIntegrationTest.java
@@ -593,6 +593,7 @@ public void testRequiredMetadataFieldsNotProvided() throws Exception {
                         "could not be found in metadata json"));
     }
 
+
     @Test
     @Transactional
     public void testSubmissionDoesNotExistException() throws Exception {
@@ -615,6 +616,27 @@ public void testSubmissionDoesNotExistException() throws Exception {
                 .andExpect(content().string("Submission with id " + submissionId + " does not exist"));
     }
 
+    @Test
+    @Transactional
+    public void testSubmissionAlreadyUploaded() throws Exception {
+        String userToken = "webinUserToken";
+        SubmissionAccount submissionAccount = getWebinUserAccount();
+        when(webinTokenService.getWebinUserAccountFromToken(anyString())).thenReturn(submissionAccount);
+        String projectTitle = "test_project_title";
+        String projectDescription = "test_project_description";
+        String submissionId = createNewSubmissionEntry(submissionAccount, SubmissionStatus.UPLOADED);
+        String metadataJson = "{\"project\": {\"title\":\"" + projectTitle + "\",\"description\":\"" + projectDescription + "\"}}";
+        HttpHeaders httpHeaders = new HttpHeaders();
+        httpHeaders.setBearerAuth(userToken);
+        mvc.perform(put("/v1/submission/" + submissionId + "/uploaded")
+                        .headers(httpHeaders)
+                        .content(metadataJson)
+                        .contentType(MediaType.APPLICATION_JSON))
+                .andExpect(status().isBadRequest())
+                .andExpect(content().string("Submission " + submissionId + " is not in status OPEN. " +
+                        "It cannot be marked as UPLOADED. Current Status: UPLOADED"));
+    }
+
     @Test
     @Transactional
     public void testMarkSubmissionStatusCorrect() throws Exception {