diff --git a/Python/pywarpx/particle_containers.py b/Python/pywarpx/particle_containers.py
index bc6b2d74106..0986985002d 100644
--- a/Python/pywarpx/particle_containers.py
+++ b/Python/pywarpx/particle_containers.py
@@ -26,7 +26,14 @@ def __init__(self, species_name):
         self.name = species_name
 
         # grab the desired particle container
-        mypc = libwarpx.warpx.multi_particle_container()
+        # if initialize_warpx() has not been called, libwarpx will not have a `warpx` attribute.
+        # We catch this error and provide the user with some useful information.
+        try:
+            mypc = libwarpx.warpx.multi_particle_container()
+        except AttributeError as e:
+            msg = "This may be caused by forgetting to call initialize_warpx() before creating a ParticleContainerWrapper."
+            raise AttributeError(msg) from e
+
         self.particle_container = mypc.get_particle_container_from_name(self.name)
 
     def add_particles(