Problem about deconvolution_fit_SV()?

[edceeyuchen]

Here is my error:
Error in solve.default(CtC) :
system is computationally singular: reciprocal condition number = 1.4343e-22
And this is my code:
SVsignatures_exp <- deconvolution_fit_SV(vcf = SV.vcf,
input_data = SV_input$mut_props,
input_signatures = SV_denovo_sigs,
sig_cols = SV_cols,
threshold = 6,
plot = TRUE,
resdir = resdir)
It's bother me ! Expecting a reply!