Target: SARS Coronavirus 3C-like Protease (the original SARS virus).
This is a repeat of the work desscribed for validating rDock and Smina for DHFR. Look here for that data and for the methodology.
| tool | # actives in top 100 |
|---|---|
| rDock | 7 |
| Smina - vina | 1 |
| Smina - vinardo | 2 |
| Smina - dkoes | 4 |
| Smina - ad4 | 5 |
rDock is the only one that performs at all, and even then not very well, especially in relation to early recall.