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Primer_items.md

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Primers

sequence
Location hg19
Location GrCh38
Melting temperature
GC content
date added
lab/user added
presence of high MAF snps
when last checked for snps UKAS wanted regular check of primers for SNPs given new data e.g. gnomad or ref changes in new genome build
measure of specificity e.g. x matches in in silico PCR/blast at y% similarity

type in primer set forward/reverse/internal oligo

Primer set

primers
success given lab conditions

Transcripts

Ensembl transcript ids
RefSeq transcript ids
exon locations
genes (account for alt genenames)

Lab conditions

M13 tags
mastermix used (e.g. Megamix, GC-RICH)
additives used (e.g. DMSO)
other reagents used?
pcr settings?

Users

name lab roles for access

Feedback

verified success of primer in other lab