diff --git a/pkgs/by-name/tl/tlpui/package.nix b/pkgs/by-name/tl/tlpui/package.nix
new file mode 100644
index 0000000000000..e1c5a1ed7b268
--- /dev/null
+++ b/pkgs/by-name/tl/tlpui/package.nix
@@ -0,0 +1,70 @@
+{
+  cairo,
+  fetchFromGitHub,
+  gobject-introspection,
+  gtk3,
+  lib,
+  pciutils,
+  python3Packages,
+  substituteAll,
+  tlp,
+  usbutils,
+  wrapGAppsHook,
+}:
+python3Packages.buildPythonPackage rec {
+  pname = "tlpui";
+  version = "1.6.5";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "d4nj1";
+    repo = "TLPUI";
+    rev = "refs/tags/tlpui-${version}";
+    hash = "sha256-pgzGhf2WDRNQ2z0hPapUJA5MLTKq92UlgjC+G78T/4s=";
+  };
+
+  patches = [
+    (substituteAll {
+      src = ./path.patch;
+      inherit tlp;
+    })
+  ];
+
+  # ignore test/test_tlp_settings.py asit relies on opening a gui which is non-trivial
+  pytestFlagsArray = [ "--ignore=test/test_tlp_settings.py" ];
+  nativeCheckInputs = [
+    gobject-introspection
+    python3Packages.pytestCheckHook
+  ];
+
+  build-system = [
+    wrapGAppsHook
+    python3Packages.poetry-core
+  ];
+
+  buildInputs = [ tlp ];
+
+  dependencies = [
+    gobject-introspection
+    gtk3
+    pciutils
+    python3Packages.pycairo
+    python3Packages.pygobject3
+    python3Packages.pyyaml
+    usbutils
+  ];
+
+  meta = {
+    changelog = "https://github.com/d4nj1/TLPUI/releases/tag/tlpui-${version}";
+    description = "A GTK user interface for TLP written in Python";
+    homepage = "https://github.com/d4nj1/TLPUI";
+    license = lib.licenses.gpl2Only;
+    longDescription = ''
+      The Python scripts in this project generate a GTK-UI to change TLP configuration files easily.
+      It has the aim to protect users from setting bad configuration and to deliver a basic overview of all the valid configuration values.
+    '';
+    platforms = lib.platforms.linux;
+    mainProgram = "tlpui";
+    maintainers = with lib.maintainers; [ grimmauld ];
+  };
+}
diff --git a/pkgs/by-name/tl/tlpui/path.patch b/pkgs/by-name/tl/tlpui/path.patch
new file mode 100644
index 0000000000000..2eeee2822ae27
--- /dev/null
+++ b/pkgs/by-name/tl/tlpui/path.patch
@@ -0,0 +1,57 @@
+diff --git a/tlpui/file.py b/tlpui/file.py
+index f0f3ecb..a9ad7f8 100644
+--- a/tlpui/file.py
++++ b/tlpui/file.py
+@@ -26,7 +26,7 @@ def get_tlp_config_defaults(tlpversion: str):
+     tlpconfig_defaults = extract_default_tlp_configs(f"{settings.workdir}/defaults/tlp-{tlpversion}.conf")
+ 
+     # update default values with intrinsic ones
+-    intrinsic_defaults_path = f"{settings.FOLDER_PREFIX}/usr/share/tlp/defaults.conf"
++    intrinsic_defaults_path = f"@tlp@/share/tlp/defaults.conf"
+     tlpconfig_defaults.update(extract_default_tlp_configs(intrinsic_defaults_path))
+ 
+     return tlpconfig_defaults
+@@ -124,7 +124,10 @@ def create_tmp_tlp_config_file(changedproperties: dict) -> str:
+     filehandler, tmpfilename = mkstemp(dir=settings.TMP_FOLDER)
+     newfile = open(tmpfilename, mode='w', encoding='utf-8')
+ 
+-    oldfile = open(settings.tlpconfigfile, encoding='utf-8')
++    try:
++        oldfile = open(settings.tlpconfigfile, encoding='utf-8')
++    except FileNotFoundError:
++        oldfile = open("@tlp@/etc/tlp.conf", encoding='utf-8')
+     lines = oldfile.readlines()
+     oldfile.close()
+ 
+diff --git a/tlpui/mainui.py b/tlpui/mainui.py
+index 0242514..da59046 100644
+--- a/tlpui/mainui.py
++++ b/tlpui/mainui.py
+@@ -115,8 +115,12 @@ def changed_items_dialog(window, tmpfilename: str, dialogtitle: str, message: st
+     scrolledwindow.set_hexpand(True)
+     scrolledwindow.set_vexpand(True)
+ 
+-    with open(settings.tlpconfigfile, encoding='utf-8') as fromfile:
+-        fromfilecontent = fromfile.readlines()
++    try:
++        with open(settings.tlpconfigfile, encoding='utf-8') as fromfile:
++            fromfilecontent = fromfile.readlines()
++    except FileNotFoundError:
++        with open("@tlp@/etc/tlp.conf", encoding='utf-8') as fromfile:
++            fromfilecontent = fromfile.readlines()
+     with open(tmpfilename, encoding='utf-8') as tofile:
+         tofilecontent = tofile.readlines()
+     diff = settings.tlpbaseconfigfile + '\n\n'
+diff --git a/tlpui/settingshelper.py b/tlpui/settingshelper.py
+index 69481c0..d769029 100644
+--- a/tlpui/settingshelper.py
++++ b/tlpui/settingshelper.py
+@@ -20,7 +20,7 @@ def exec_command(commands: [str]):
+ 
+ def get_tlp_config_file(prefix: str) -> str:
+     """Select tlp config file by prefix."""
+-    return f"{prefix}/etc/tlp.conf"
++    return f"{prefix}/etc/tlp.d/30-tlpui.conf"
+ 
+ 
+ def check_binaries_exist(flatpak_folder_prefix: str) -> None: