diff --git a/pkgs/development/compilers/llvm/common/llvm/default.nix b/pkgs/development/compilers/llvm/common/llvm/default.nix
index 0716453c34c94..72d626eed749a 100644
--- a/pkgs/development/compilers/llvm/common/llvm/default.nix
+++ b/pkgs/development/compilers/llvm/common/llvm/default.nix
@@ -30,6 +30,7 @@
 , debugVersion ? false
 , doCheck ? (if lib.versionOlder release_version "15" then stdenv.isLinux else true)
   && (!stdenv.isx86_32 /* TODO: why */) && (!stdenv.hostPlatform.isMusl)
+  && !(stdenv.hostPlatform.isPower64 && stdenv.hostPlatform.isBigEndian)
   && (stdenv.hostPlatform == stdenv.buildPlatform)
 , enableManpages ? false
 , enableSharedLibraries ? !stdenv.hostPlatform.isStatic