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Evaluate (f)utility of protein imputation on DIA data #12

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sgosline opened this issue Sep 17, 2021 · 1 comment
Open

Evaluate (f)utility of protein imputation on DIA data #12

sgosline opened this issue Sep 17, 2021 · 1 comment
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@sgosline
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We need to determine if the imputation can help our data.

I'd first run the DREAM AI tool, which has instructions here:
https://github.com/PNNL-CompBio/proteomicsTumorDeconv/tree/main/imputation

Let's run this about 10 times to create 10 imputed datasets, then plot PCA of each of the datasets side by side, compared to the original data. If things look stable, we can continue.

@CamiloPosso
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Pretty futile :(

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