README.md

StarCats

epilipidomics tools for Lipostar 2 developed by Team SysMedOs

This repository contains special version of epilipidomics tools which can be used with Lipostar 2 software.

• LipidLynxX

  

  • The LipidLynxX project is aimed to provide a unified identifier for major lipids, especially oxidized lipids in the epilipidome.
  • Project repository: https://github.com/SysMedOs/LipidLynxX
  • Publication: Zhixu Ni, Maria Fedorova. "LipidLynxX: a data transfer hub to support integration of large scale lipidomics datasets"
  • DOI: 10.1016/j.freeradbiomed.2019.04.027

• LPPtiger

  

  • LPPtiger is a pioneer in the field of high-throughput identification of oxidized lipids (epilipids).
  • Project repository: https://github.com/SysMedOs/lpptiger
  • Publication: Ni, Zhixu, Georgia Angelidou, Ralf Hoffmann, and Maria Fedorova. "LPPtiger software for lipidome-specific prediction and identification of oxidized phospholipids from LC-MS datasets." Scientific Reports 7, Article number: 15138 (2017).
  • DOI: 10.1038/s41598-017-15363-z

About Lipostar 2

Lipostar is the latest software from Molecular Discovery, developed to assist LC/MS-based lipidomics from the very beginning (direct import of raw data files) to the final goal (lipid identification, statistical analysis, report generation).

• Publication: Goracci L; Tortorella S; Tiberi P; Pellegrino RM; Di Veroli A; Valeri A; Cruciani G, Lipostar, a Comprehensive Platform-Neutral Cheminformatics Tool for Lipidomics. Anal. Chem., 2017, 89 (11), pp 6257–6264
• DOI: 10.1021/acs.analchem.7b01259

Read more about Lipostar:

https://www.moldiscovery.com/software/lipostar/

Download epilipidomics tools for Lipostar

Please find the latest .exe version in the release page. https://github.com/SysMedOs/StarCats/releases/

Instructions

• LipidLynxX

  • Download the LipidLynxX_for_Lipostar.zip package
  • unzip it into a folder
  • start Lipostar 2
  • open Lipostar perferences
  • set the path of cli_lynx.exe in Lipostar perferences
  • click on "Save And Exit" to save the settings

• LPPtiger

  • download the LPPtiger_for_Lipostar.zip package

  • unzip it into a folder

  • find the LPPtiger.exe to star the GUI of LPPtiger for Lipostar 2

    

  • load the .csv exported from Lipostrar2 for LPPtiger and set parameters on the GUI of LPPtiger and click on "Run analysis"

  • run status will be displayed on the GUI, wait until the run finish.

    

  • the output .csv file can be imported back to Lipostar 2