From e29bfde681bb9dcca129da2df99c53f80c888206 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Tue, 1 Oct 2024 11:07:38 +0100 Subject: [PATCH 01/33] add ukb_image --- conf/container.config | 11 +++++++---- 1 file changed, 7 insertions(+), 4 deletions(-) diff --git a/conf/container.config b/conf/container.config index 567fc54..b59c106 100644 --- a/conf/container.config +++ b/conf/container.config @@ -1,11 +1,14 @@ process { - withLabel: flashpca_image { - container = "ktetleycampbell/flashpca:1.0" + withLabel: ukb_image { + container = "olivierlabayle/ukbmain:0.5" + } + withLabel: pca_image { + container = "roskamsh/flashpca:0.1.0" } withLabel: tl_core_image { - container = "olivierlabayle/tl-core:0.9.0" + container = "olivierlabayle/tl-core:0.10" } - withLabel: bgen_python_image { + withLabel: r_python_image { container = "roskamsh/bgen_env:0.2.0" } withLabel: qctool_image { From 913ea13c5e41d150a3ad635f61fcf96f175ab630 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Tue, 1 Oct 2024 11:07:54 +0100 Subject: [PATCH 02/33] add new cluster options --- conf/eddie.config | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) diff --git a/conf/eddie.config b/conf/eddie.config index a7ae03b..0ea579a 100644 --- a/conf/eddie.config +++ b/conf/eddie.config @@ -6,7 +6,7 @@ executor { } process { - clusterOptions = { task.memory ? "-l h_vmem=${task.memory.bytes/task.cpus}" : null } + clusterOptions = { task.memory ? "-l rl9=false,h_vmem=${task.memory.bytes/task.cpus}" : "-l rl9=false" } stageInMode = 'symlink' scratch = 'false' penv = { task.cpus > 1 ? "sharedmem" : null } @@ -19,7 +19,7 @@ process { beforeScript = """ . /etc/profile.d/modules.sh - module load 'roslin/singularity/3.5.3' + module load 'singularity' unset XDG_RUNTIME_DIR export SINGULARITY_TMPDIR="\$TMPDIR" """ From 7fd049d02fc21bac421cfbccf44e6ba67f005330 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Tue, 1 Oct 2024 11:08:49 +0100 Subject: [PATCH 03/33] update to recent targene code and rearrange subworkflows/modules --- main.nf | 190 ++++++++++++++------------------------------------------ 1 file changed, 46 insertions(+), 144 deletions(-) diff --git a/main.nf b/main.nf index f72bdae..35a6f94 100644 --- a/main.nf +++ b/main.nf @@ -2,158 +2,60 @@ nextflow.enable.dsl = 2 // Default parameters -params.OUTDIR = "${launchDir}/results" -params.DECRYPTED_DATASET = "NO_FILE" -params.COHORT = "UKBB" -params.TRAITS_CONFIG = "NO_UKB_TRAIT_CONFIG" -params.WITHDRAWAL_LIST = 'NO_WITHDRAWAL_LIST' -params.QC_FILE = "NO_QC_FILE" +params.TRAITS_DATASET = "You need to provide a Traits dataset." +params.UKB_ENCODING_FILE = "NO_UKB_ENCODING_FILE" params.MAF_THRESHOLD = 0.01 +params.COHORT = "UKB" +params.UKB_CONFIG = "${projectDir}/assets/ukbconfig.yaml" +params.UKB_WITHDRAWAL_LIST = "${projectDir}/assets/NO_WITHDRAWAL_LIST" +params.OUTDIR = "${launchDir}/results" +params.NB_PCS = 50 +params.QC_FILE = "${projectDir}/assets/NO_QC_FILE" +params.FLASHPCA_EXCLUSION_REGIONS = "${projectDir}/assets/exclusion_regions_hg19.txt" -// Define functions -def longest_common_prefix(List strs) { - def longest_common = null - for (s in strs) { - if (longest_common == null) { - longest_common = s - } else { - for (i=0; i<=longest_common.length() - 1; i++) { - if (longest_common.charAt(i) != s.charAt(i)) { - longest_common = longest_common.substring(0, i) - break - } - } - } - } - return longest_common -} - -// Import processes -include { pull_ld; compile_ld_information } from './modules/extract.nf' -include { IIDGenotypes } from './modules/genotypes.nf' -include { FlashPCA; AdaptFlashPCA; ScreePlot } from './modules/confounders.nf' - -workflow importSNPs { - take: - bgen_files - bgen_prefix - main: - Channel - .fromPath(params.INPUT_SNPS, checkIfExists: true) - .splitCsv(header:true) - .map { - row -> tuple(row.RSID, row.CHR, row.POS) - } - .set { snps_ch } - - snps_ch - .combine(bgen_prefix) - .combine(bgen_files) - .set { snps_bgen_ch } - - emit: - snps_bgen_ch -} - -workflow configureBGEN { - main: - bgen_files = Channel.fromFilePairs("$params.BGEN_FILES", size: -1, checkIfExists: true) - - bgen_files - .multiMap{ - prefix, files -> - files: [files] - prefix: prefix } - .set { bgen_ch } - - emit: - files = bgen_ch.files - prefix = bgen_ch.prefix -} - -workflow computeLD { - take: - snps_bgen - - main: - ld_ch = pull_ld(snps_bgen) - // filter for just sqlite files and collect - ld_ch.map{ snp, chr, pos, sqlite_files -> sqlite_files } - .collect() - .set { sqlite_ch } - - // compile LD_block information - csv_ch = Channel.fromPath(params.INPUT_SNPS, checkIfExists: true) - script_ch = Channel.fromPath("$projectDir/py/convert_sqlite.py") - qtls_ch = compile_ld_information(sqlite_ch, csv_ch, script_ch) - emit: - ld_blocks = qtls_ch.ld_pca -} - -workflow extractTraits { - if (params.COHORT == "UKBB") { - traits_config = Channel.value(file("$params.TRAITS_CONFIG")) - withdrawal_list = Channel.value(file("$params.WITHDRAWAL_LIST")) - if (params.DECRYPTED_DATASET == "NO_FILE") { - encrypted_dataset = Channel.value(file("$params.ENCRYPTED_DATASET")) - encoding_file = Channel.value(file("$params.ENCODING_FILE")) - UKBFieldsList(traits_config) - decrypted_dataset = UKBConv(UKBFieldsList.out, encrypted_dataset, encoding_file) - } - else { - decrypted_dataset = Channel.value(file("$params.DECRYPTED_DATASET")) - } - - phenoInput = TraitsFromUKB(decrypted_dataset, traits_config, withdrawal_list) - } - else { - phenoInput = Channel.fromPath("$params.DECRYPTED_DATASET", checkIfExists: true) - } - - emit: - phenoInput -} - -workflow generateIIDGenotypes { - take: - traits - ld_blocks - - main: - qc_file = Channel.value(file("$params.QC_FILE")) - flashpca_excl_reg = Channel.value(file("$params.FLASHPCA_EXCLUSION_REGIONS")) - bed_files_ch = Channel.fromFilePairs("$params.BED_FILES", size: 3, checkIfExists: true){ file -> file.baseName } - - IIDGenotypes(flashpca_excl_reg, ld_blocks, bed_files_ch, qc_file, traits) - - emit: - IIDGenotypes.out -} - -workflow geneticConfounders { - take: - iid_genotypes - - main: - FlashPCA(iid_genotypes) - AdaptFlashPCA(FlashPCA.out.pcs) - ScreePlot(FlashPCA.out.pve) -} +// Import subworkflows +include { ImportSNPs; ComputeLD } from './subworkflows/ldblocks.nf' +include { IIDGenotypes; FlashPCA; ScreePlot } from './subworkflows/confounders.nf' +include { ExtractTraits } from './subworkflows/extract_traits.nf' // Define workflow workflow { - configureBGEN() - - importSNPs(configureBGEN.out.files, configureBGEN.out.prefix) - - computeLD(importSNPs.out) + // Define Parameters + ukb_encoding_file = params.UKB_ENCODING_FILE + ukb_config = Channel.value(file("$params.UKB_CONFIG", checkIfExists: true)) + ukb_withdrawal_list = Channel.value(file("$params.UKB_WITHDRAWAL_LIST", checkIfExists: true)) + traits_dataset = Channel.value(file("$params.TRAITS_DATASET", checkIfExists: true)) - extractTraits() + qc_file = Channel.value(file("$params.QC_FILE", checkIfExists: true)) + flashpca_excl_reg = Channel.value(file("$params.FLASHPCA_EXCLUSION_REGIONS", checkIfExists: true)) + bed_files = Channel.fromFilePairs("$params.BED_FILES", size: 3, checkIfExists: true){ file -> file.baseName } + bgen_files = Channel.fromPath("$params.BGEN_FILES", checkIfExists: true).collect().toList() - generateIIDGenotypes(extractTraits.out, computeLD.out.ld_blocks) + // Compute LD blocks + ImportSNPs(bgen_files) - geneticConfounders(generateIIDGenotypes.out) + ComputeLD(ImportSNPs.out) + + // Extract Traits + ExtractTraits( + traits_dataset, + ukb_config, + ukb_withdrawal_list, + ukb_encoding_file, + ) + + // IID Genotypes + IIDGenotypes( + flashpca_excl_reg, + ComputeLD.out.ld_blocks, + bed_files, + qc_file, + ExtractTraits.out, + ) + + // PCA + FlashPCA(IIDGenotypes.out) + ScreePlot(FlashPCA.out.pve) } - From 85725e79427f392416e9983e4db5c7772c1fb3f5 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Tue, 1 Oct 2024 11:10:39 +0100 Subject: [PATCH 04/33] working test config with GenOMICC data --- test.config | 9 +++++++++ 1 file changed, 9 insertions(+) create mode 100644 test.config diff --git a/test.config b/test.config new file mode 100644 index 0000000..2e4b6a5 --- /dev/null +++ b/test.config @@ -0,0 +1,9 @@ +params { + COHORT = "GENOMICC" + INPUT_SNPS = "${launchDir}/input/test.csv" + BGEN_FILES = "/exports/igmm/eddie/ponting-lab/breeshey/data/genomicc/imputed/genomic-isaric/GenOMICC_ISARIC_chr*.{bgen,sample,bgen.bgi}" + BED_FILES = "/exports/igmm/eddie/ponting-lab/breeshey/data/genomicc/geno_byChr/wp5-gwas-r9-genomicc-isaric4c-nodupl-phenoind_chr*.{bed,bim,fam}" + TRAITS_DATASET = "/exports/igmm/eddie/ponting-lab/breeshey/data/genomicc/pheno/genomicc.allcohorts.pheno.withdate.withcovariates.withconfounders.filt.csv" + FLASHPCA_EXCLUSION_REGIONS = "${projectDir}/assets/exclusion_regions_hg38.txt" + NB_PCS = 5 +} From b7e7ffc0eec9a9fb69b313d22b9bb8480b0fc19f Mon Sep 17 00:00:00 2001 From: roskamsh Date: Tue, 1 Oct 2024 11:11:25 +0100 Subject: [PATCH 05/33] remove old extract module --- modules/extract.nf | 69 ---------------------------------------------- 1 file changed, 69 deletions(-) delete mode 100644 modules/extract.nf diff --git a/modules/extract.nf b/modules/extract.nf deleted file mode 100644 index 7c155c5..0000000 --- a/modules/extract.nf +++ /dev/null @@ -1,69 +0,0 @@ -process pull_ld { - label 'qctool_image' - - input: - tuple val(RSID), val(CHR), val(POS), val(PREFIX), path(BGEN_FILES) - - output: - tuple val(RSID), val(CHR), val(POS), path("*.sqlite") - - script: - """ - if [[ "${params.COHORT}" == "UKBB" ]]; then - CHR_FORMAT=\$(echo ${CHR} | xargs printf "%02d" ) - elif [[ "${params.COHORT}" == "GENOMICC" ]]; then - CHR_FORMAT=\$(echo chr${CHR} ) - fi - - BGEN_FILE="${PREFIX}${CHR}.bgen" - SAMPLE_FILE="${PREFIX}${CHR}.sample" - - # Define lower and upper bounds to scan for LD - LOWER=\$((${POS} - 10000000)) - UPPER=\$((${POS} + 10000000)) - - # Account for the possibility that the scan range becomes negative. - if [ \$LOWER -lt 0 ] - then - LOWER="0" - fi - - if [ \$UPPER -lt 0 ] - then - UPPER="0" - fi - - OUTNAME=\$( echo ${RSID} | sed 's/:/_/g' ) - - # Use bgenix to create a new .bgen file with the info for just the SNP of interest + index file - bgenix -g \$BGEN_FILE -incl-rsids ${RSID} > "\$OUTNAME.bgen" - bgenix -g "\$OUTNAME.bgen" -index - - bgenix -g \$BGEN_FILE -incl-range "\$CHR_FORMAT:\$LOWER-\$UPPER" | qctool -g - -filetype bgen \ - -s \$SAMPLE_FILE -compute-ld-with "\$OUTNAME.bgen" \$SAMPLE_FILE -old "sqlite://\$OUTNAME.sqlite:LD" \ - -min-r2 0.05 - """ - -} - -process compile_ld_information { - label 'bgen_python_image' - publishDir("$params.OUTDIR/ld_blocks/", mode: "copy", pattern: "*LD_block*") - - input: - path sqlite_files - path csv - path script - - output: - path "LD_for_PCA.csv", emit: ld_pca - path "*_with_LD_blocks.csv" - path "LD_block_length_histogram.png" - - script: - """ - python ${script} --input ${csv} - """ - -} - From 9fe767b83cfac51a4484f35e74029e83fed23df9 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Tue, 1 Oct 2024 11:11:37 +0100 Subject: [PATCH 06/33] move these modules to confounders.nf --- modules/genotypes.nf | 101 ------------------------------------------- 1 file changed, 101 deletions(-) delete mode 100644 modules/genotypes.nf diff --git a/modules/genotypes.nf b/modules/genotypes.nf deleted file mode 100644 index cb184af..0000000 --- a/modules/genotypes.nf +++ /dev/null @@ -1,101 +0,0 @@ -process filterBED{ - label 'bigmem' - label 'tl_core_image' - publishDir "$params.OUTDIR/qc_filtered_chromosomes", mode: 'symlink' - - input: - tuple val(chr_id), file(bedfiles), path(qcfile), path(ld_blocks), path(traits) - - output: - path "filtered.*", emit: filtered_bedfiles - - script: - prefix = bedfiles[0].toString().minus('.bed') - qc_file = params.QC_FILE !== 'NO_QC_FILE' ? "--qcfile $qcfile" : '' - - """ - TEMPD=\$(mktemp -d) - JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/TargeneCore.jl --startup-file=no /TargeneCore.jl/bin/prepare_confounders.jl \ - --input $prefix --output filtered.$prefix $qc_file --maf-threshold $params.MAF_THRESHOLD \ - --ld-blocks $ld_blocks --traits $traits filter - """ -} - - -process thinByLD{ - label 'bigmem' - label 'plink2_image' - publishDir "$params.OUTDIR/ld_pruned_chromosomes", mode: 'symlink' - - input: - path flashpca_excl_reg - path bedfiles - - output: - path "LDpruned.*" - - script: - prefix = bedfiles[0].toString().minus('.bed') - """ - plink2 --bfile $prefix --indep-pairwise 1000 50 0.05 --exclude range $flashpca_excl_reg - plink2 --bfile $prefix --extract plink2.prune.in --make-bed --out LDpruned.$prefix - """ -} - - -process mergeBEDS{ - label 'bigmem' - label 'tl_core_image' - publishDir "$params.OUTDIR/merged_genotypes", mode: 'symlink' - - input: - path files - - output: - path "ukbb_merged*" - - script: - """ - TEMPD=\$(mktemp -d) - JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/TargeneCore.jl --startup-file=no /TargeneCore.jl/bin/prepare_confounders.jl --input LDpruned. --output ukbb_merged merge - """ - -} - -process SampleQCFilter { - label 'bigmem' - label 'plink2_image' - publishDir "$params.OUTDIR/iid_genotypes", mode: 'symlink' - - input: - path merged_bed_files - - output: - path "qc_filtered*" - - script: - "plink2 --bfile ukbb_merged --make-bed --hwe 1e-10 --geno --mind --out qc_filtered" -} - - -workflow IIDGenotypes{ - take: - flashpca_excl_reg - ld_blocks - bed_files - qc_file - sample_ids - - main: - combined_ch = bed_files - .combine(qc_file) - .combine(ld_blocks) - .combine(sample_ids) - filtered_bedfiles = filterBED(combined_ch) - ld_pruned = thinByLD(flashpca_excl_reg, filtered_bedfiles) - mergeBEDS(ld_pruned.collect()) - SampleQCFilter(mergeBEDS.out.collect()) - - emit: - SampleQCFilter.out -} From 008ce197c12be9ab2f75d42814e53eb2f49e9df6 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Tue, 1 Oct 2024 11:11:52 +0100 Subject: [PATCH 07/33] add genotypes.nf processes into here --- modules/confounders.nf | 106 +++++++++++++++++++++++++++++++++-------- 1 file changed, 87 insertions(+), 19 deletions(-) diff --git a/modules/confounders.nf b/modules/confounders.nf index d823eda..3d7ce82 100644 --- a/modules/confounders.nf +++ b/modules/confounders.nf @@ -1,40 +1,108 @@ -process FlashPCA { - label "multithreaded" - label 'flashpca_image' +include { longest_prefix } from './utils' + +process filterBED { + label 'bigmem' + label 'tl_core_image' + publishDir "${params.OUTDIR}/qc_filtered_chromosomes", mode: 'symlink' input: - path bedfiles - + tuple val(chr_id), file(bedfiles), path(qcfile), path(ld_blocks), path(traits) + output: - path "pcs.txt", emit: pcs - path "pve.txt", emit: pve - + path "filtered.*", emit: filtered_bedfiles + script: - prefix = bedfiles[0].toString().minus('.bed') - "/home/flashpca-user/flashpca/flashpca --bfile $prefix --ndim $params.NB_PCS --numthreads $task.cpus" + input_prefix = bedfiles[0].toString().minus('.bed') + qc_file = qcfile.getName() != 'NO_QC_FILE' ? "--qc-file ${qcfile}" : '' + ld_blocks = ld_blocks.getName() != 'NO_LD_BLOCKS' ? "--ld-blocks-file ${ld_blocks}" : '' + """ + TEMPD=\$(mktemp -d) + JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/TargeneCore.jl --startup-file=no /TargeneCore.jl/targenecore.jl \ + filter-chromosome ${input_prefix} filtered.${input_prefix} ${traits} \ + ${qc_file} \ + --maf-threshold=${params.MAF_THRESHOLD} \ + ${ld_blocks} + """ } -process AdaptFlashPCA { - label 'tl_core_image' +process thinByLD { label 'bigmem' - publishDir "$params.OUTDIR/covariates/", mode: 'symlink' - + label 'plink2_image' + publishDir "${params.OUTDIR}/ld_pruned_chromosomes", mode: 'symlink' + + input: + tuple path(bed), path(bim), path(fam), path(flashpca_excl_reg) + + output: + path "LDpruned.*" + + script: + prefix = bed.toString().minus('.bed') + """ + plink2 --memory ${task.memory.toMega()} --bfile ${prefix} --indep-pairwise 1000 50 0.05 --exclude range ${flashpca_excl_reg} + plink2 --memory ${task.memory.toMega()} --bfile ${prefix} --extract plink2.prune.in --make-bed --out LDpruned.${prefix} + """ +} + + +process mergeBEDS{ + label 'bigmem' + label 'tl_core_image' + publishDir "${params.OUTDIR}/merged_genotypes", mode: 'symlink' input: - path flashpca_out + tuple val(genotypes_id), path(bed_files) output: - path "pcs.csv" - + tuple val(genotypes_id), path("${output_prefix}*") + script: + output_prefix = "${genotypes_id}.merged" + input_prefix = longest_prefix(bed_files) """ TEMPD=\$(mktemp -d) - JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/TargeneCore.jl --startup-file=no /TargeneCore.jl/bin/prepare_confounders.jl --input $flashpca_out --output pcs.csv adapt + JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/TargeneCore.jl --startup-file=no /TargeneCore.jl/targenecore.jl \ + merge-beds ${input_prefix} ${output_prefix} """ + +} + +process SampleQCFilter { + label 'bigmem' + label 'plink2_image' + publishDir "${params.OUTDIR}/iid_genotypes", mode: 'symlink' + + input: + tuple val(genotypes_id), path(merged_bed_files) + + output: + tuple val(genotypes_id), path("${output_prefix}*") + + script: + input_prefix = "${genotypes_id}.merged" + output_prefix = "${input_prefix}.qc" + "plink2 --bfile ${input_prefix} --make-bed --hwe 1e-10 --geno --mind --out ${output_prefix}" +} + + +process FlashPCA { + label "multithreaded" + label 'pca_image' + + input: + tuple val(genotypes_id), path(bedfiles) + + output: + path "pcs.${genotypes_id}.txt", emit: pcs + path "pve.${genotypes_id}.txt", emit: pve + + script: + input_prefix = bedfiles[0].toString().minus('.bed') + "/home/flashpca-user/flashpca/flashpca --bfile ${input_prefix} --ndim ${params.NB_PCS} --numthreads ${task.cpus} --suffix .${genotypes_id}.txt" } process ScreePlot { - label 'bgen_python_image' + label 'r_python_image' publishDir "$params.OUTDIR/pca/", mode: 'symlink' input: From 4227ecb2bd205cbeccdd6591bb147b84baf57e89 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Tue, 1 Oct 2024 11:12:11 +0100 Subject: [PATCH 08/33] update to new targene version and rearrange subworkflows/modules --- assets/NO_QC_FILE | 0 assets/NO_WITHDRAWAL_LIST | 0 assets/exclusion_regions_hg19.txt | 4 + assets/exclusion_regions_hg38.txt | 4 + assets/ukbconfig.yaml | 17280 ++++++++++++++++++++++++++++ modules/extract_traits.nf | 55 + modules/ldblocks.nf | 72 + modules/utils.nf | 27 + subworkflows/confounders.nf | 26 + subworkflows/extract_traits.nf | 31 + subworkflows/ldblocks.nf | 37 + test/bed/ukb_chr1.bed | 81 + test/bed/ukb_chr1.bim | 100 + test/bed/ukb_chr1.fam | 3202 ++++++ test/bed/ukb_chr2.bed | Bin 0 -> 120153 bytes test/bed/ukb_chr2.bim | 150 + test/bed/ukb_chr2.fam | 3202 ++++++ test/bed/ukb_chr3.bed | 115 + test/bed/ukb_chr3.bim | 200 + test/bed/ukb_chr3.fam | 3202 ++++++ test/bgen/ukb_chr1.bgen | Bin 0 -> 48492 bytes test/bgen/ukb_chr1.bgen.bgi | Bin 0 -> 12288 bytes test/bgen/ukb_chr1.sample | 3204 ++++++ test/bgen/ukb_chr2.bgen | Bin 0 -> 66284 bytes test/bgen/ukb_chr2.bgen.bgi | Bin 0 -> 20480 bytes test/bgen/ukb_chr2.sample | 3204 ++++++ test/bgen/ukb_chr3.bgen | Bin 0 -> 76939 bytes test/bgen/ukb_chr3.bgen.bgi | Bin 0 -> 20480 bytes test/bgen/ukb_chr3.sample | 3204 ++++++ test/dataset.csv | 501 + test/qc_file.csv | 451 + test/snps.csv | 4 + test/test.config | 12 + test/traits.csv | 501 + test/ukbconfig_small.yaml | 163 + test/withdrawal_list.txt | 2 + 36 files changed, 39034 insertions(+) create mode 100644 assets/NO_QC_FILE create mode 100644 assets/NO_WITHDRAWAL_LIST create mode 100644 assets/exclusion_regions_hg19.txt create mode 100644 assets/exclusion_regions_hg38.txt create mode 100644 assets/ukbconfig.yaml create mode 100644 modules/extract_traits.nf create mode 100644 modules/ldblocks.nf create mode 100644 modules/utils.nf create mode 100644 subworkflows/confounders.nf create mode 100644 subworkflows/extract_traits.nf create mode 100644 subworkflows/ldblocks.nf create mode 100644 test/bed/ukb_chr1.bed create mode 100644 test/bed/ukb_chr1.bim create mode 100644 test/bed/ukb_chr1.fam create mode 100644 test/bed/ukb_chr2.bed create mode 100644 test/bed/ukb_chr2.bim create mode 100644 test/bed/ukb_chr2.fam create mode 100644 test/bed/ukb_chr3.bed create mode 100644 test/bed/ukb_chr3.bim create mode 100644 test/bed/ukb_chr3.fam create mode 100644 test/bgen/ukb_chr1.bgen create mode 100644 test/bgen/ukb_chr1.bgen.bgi create mode 100644 test/bgen/ukb_chr1.sample create mode 100644 test/bgen/ukb_chr2.bgen create mode 100644 test/bgen/ukb_chr2.bgen.bgi create mode 100644 test/bgen/ukb_chr2.sample create mode 100644 test/bgen/ukb_chr3.bgen create mode 100644 test/bgen/ukb_chr3.bgen.bgi create mode 100644 test/bgen/ukb_chr3.sample create mode 100644 test/dataset.csv create mode 100644 test/qc_file.csv create mode 100644 test/snps.csv create mode 100644 test/test.config create mode 100644 test/traits.csv create mode 100644 test/ukbconfig_small.yaml create mode 100644 test/withdrawal_list.txt diff --git a/assets/NO_QC_FILE b/assets/NO_QC_FILE new file mode 100644 index 0000000..e69de29 diff --git a/assets/NO_WITHDRAWAL_LIST b/assets/NO_WITHDRAWAL_LIST new file mode 100644 index 0000000..e69de29 diff --git a/assets/exclusion_regions_hg19.txt b/assets/exclusion_regions_hg19.txt new file mode 100644 index 0000000..948c53d --- /dev/null +++ b/assets/exclusion_regions_hg19.txt @@ -0,0 +1,4 @@ +5 44000000 51500000 r1 +6 25000000 33500000 r2 +8 8000000 12000000 r3 +11 45000000 57000000 r4 diff --git a/assets/exclusion_regions_hg38.txt b/assets/exclusion_regions_hg38.txt new file mode 100644 index 0000000..79730ad --- /dev/null +++ b/assets/exclusion_regions_hg38.txt @@ -0,0 +1,4 @@ +5 43999898 52204166 r1 +6 24999772 33532223 r2 +8 8142478 12142491 r3 +11 44978449 57232526 r4 diff --git a/assets/ukbconfig.yaml b/assets/ukbconfig.yaml new file mode 100644 index 0000000..ac145b5 --- /dev/null +++ b/assets/ukbconfig.yaml @@ -0,0 +1,17280 @@ +traits: + - fields: + - "41202" + - "41204" + phenotypes: + - name: "J40-J47 Chronic lower respiratory diseases" + codings: + - "J40" + - "J41" + - "J410" + - "J411" + - "J418" + - "J42" + - "J43" + - "J430" + - "J431" + - "J432" + - "J438" + - "J439" + - "J44" + - "J440" + - "J441" + - "J448" + - "J449" + - "J45" + - "J450" + - "J451" + - "J458" + - "J459" + - "J46" + - "J47" + - name: "G25 Other extrapyramidal and movement disorders" + codings: + - "G254" + - "G255" + - "G256" + - "G258" + - "G259" + - "G250" + - "G251" + - "G252" + - "G253" + - name: "G20 Parkinson's disease" + codings: + - "G20" + - name: "L72 Follicular cysts of skin and subcutaneous tissue" + codings: + - "L720" + - "L721" + - "L722" + - "L728" + - "L729" + - name: "J34 Other disorders of nose and nasal sinuses" + codings: + - "J341" + - "J342" + - "J343" + - "J348" + - "J340" + - name: "H15-H22 Disorders of sclera, cornea, iris and ciliary body" + codings: + - "H15" + - "H150" + - "H151" + - "H158" + - "H159" + - "H16" + - "H160" + - "H161" + - "H162" + - "H163" + - "H164" + - "H168" + - "H169" + - "H17" + - "H170" + - "H171" + - "H178" + - "H179" + - "H18" + - "H180" + - "H181" + - "H182" + - "H183" + - "H184" + - "H185" + - "H186" + - "H187" + - "H188" + - "H189" + - "H19" + - "H190" + - "H191" + - "H192" + - "H193" + - "H198" + - "H20" + - "H200" + - "H201" + - "H202" + - "H208" + - "H209" + - "H21" + - "H210" + - "H211" + - "H212" + - "H213" + - "H214" + - "H215" + - "H218" + - "H219" + - "H22" + - "H220" + - "H221" + - "H228" + - name: "O26 Maternal care for other conditions predominantly related to pregnancy" + codings: + - "O264" + - "O265" + - "O266" + - "O267" + - "O268" + - "O269" + - "O260" + - "O261" + - "O262" + - "O263" + - name: "O20 Haemorrhage in early pregnancy" + codings: + - "O200" + - "O208" + - "O209" + - name: "O94-O99 Other obstetric conditions, not elsewhere classified" + codings: + - "O94" + - "O95" + - "O96" + - "O960" + - "O961" + - "O969" + - "O97" + - "O970" + - "O971" + - "O979" + - "O98" + - "O980" + - "O981" + - "O982" + - "O983" + - "O984" + - "O985" + - "O986" + - "O987" + - "O988" + - "O989" + - "O99" + - "O990" + - "O991" + - "O992" + - "O993" + - "O994" + - "O995" + - "O996" + - "O997" + - "O998" + - name: "O20-O29 Other maternal disorders predominantly related to pregnancy" + codings: + - "O20" + - "O200" + - "O208" + - "O209" + - "O21" + - "O210" + - "O211" + - "O212" + - "O218" + - "O219" + - "O22" + - "O220" + - "O221" + - "O222" + - "O223" + - "O224" + - "O225" + - "O228" + - "O229" + - "O23" + - "O230" + - "O231" + - "O232" + - "O233" + - "O234" + - "O235" + - "O239" + - "O24" + - "O240" + - "O241" + - "O242" + - "O243" + - "O244" + - "O249" + - "O25" + - "O26" + - "O260" + - "O261" + - "O262" + - "O263" + - "O264" + - "O265" + - "O266" + - "O267" + - "O268" + - "O269" + - "O28" + - "O280" + - "O281" + - "O282" + - "O283" + - "O284" + - "O285" + - "O288" + - "O289" + - "O29" + - "O290" + - "O291" + - "O292" + - "O293" + - "O294" + - "O295" + - "O296" + - "O298" + - "O299" + - name: "A30-A49 Other bacterial diseases" + codings: + - "A418" + - "A419" + - "A42" + - "A420" + - "A421" + - "A422" + - "A427" + - "A428" + - "A429" + - "A43" + - "A430" + - "A431" + - "A438" + - "A439" + - "A44" + - "A440" + - "A441" + - "A448" + - "A449" + - "A46" + - "A48" + - "A480" + - "A481" + - "A482" + - "A483" + - "A484" + - "A488" + - "A49" + - "A490" + - "A491" + - "A492" + - "A493" + - "A498" + - "A499" + - "A30" + - "A300" + - "A301" + - "A302" + - "A303" + - "A304" + - "A305" + - "A308" + - "A309" + - "A31" + - "A310" + - "A311" + - "A318" + - "A319" + - "A32" + - "A320" + - "A321" + - "A327" + - "A328" + - "A329" + - "A33" + - "A34" + - "A35" + - "A36" + - "A360" + - "A361" + - "A362" + - "A363" + - "A368" + - "A369" + - "A37" + - "A370" + - "A371" + - "A378" + - "A379" + - "A38" + - "A39" + - "A390" + - "A391" + - "A392" + - "A393" + - "A394" + - "A395" + - "A398" + - "A399" + - "A40" + - "A400" + - "A401" + - "A402" + - "A403" + - "A408" + - "A409" + - "A41" + - "A410" + - "A411" + - "A412" + - "A413" + - "A414" + - "A415" + - name: "K44 Diaphragmatic hernia" + codings: + - "K440" + - "K441" + - "K449" + - name: "K40 Inguinal hernia" + codings: + - "K400" + - "K401" + - "K402" + - "K403" + - "K404" + - "K409" + - name: "K41 Femoral hernia" + codings: + - "K410" + - "K411" + - "K412" + - "K413" + - "K414" + - "K419" + - name: "K42 Umbilical hernia" + codings: + - "K420" + - "K421" + - "K429" + - name: "K43 Ventral hernia" + codings: + - "K437" + - "K439" + - "K430" + - "K431" + - "K432" + - "K433" + - "K434" + - "K435" + - "K436" + - name: "G51 Facial nerve disorders" + codings: + - "G510" + - "G511" + - "G512" + - "G513" + - "G514" + - "G518" + - "G519" + - name: "G57 Mononeuropathies of lower limb" + codings: + - "G570" + - "G571" + - "G572" + - "G573" + - "G574" + - "G575" + - "G576" + - "G578" + - "G579" + - name: "G56 Mononeuropathies of upper limb" + codings: + - "G560" + - "G561" + - "G562" + - "G563" + - "G564" + - "G568" + - "G569" + - name: "G55 Nerve root and plexus compressions in diseases classified elsewhere" + codings: + - "G550" + - "G551" + - "G552" + - "G553" + - "G558" + - name: "E66 Obesity" + codings: + - "E660" + - "E661" + - "E662" + - "E668" + - "E669" + - name: "M05-M14 Inflammatory polyarthropathies" + codings: + - "M0750" + - "M0751" + - "M0752" + - "M0753" + - "M0754" + - "M0755" + - "M0756" + - "M0757" + - "M0758" + - "M0759" + - "M076" + - "M0760" + - "M0761" + - "M0762" + - "M0763" + - "M0764" + - "M0765" + - "M0766" + - "M0767" + - "M0768" + - "M0769" + - "M08" + - "M080" + - "M0800" + - "M0801" + - "M0802" + - "M0803" + - "M0804" + - "M0805" + - "M0806" + - "M0807" + - "M0808" + - "M0809" + - "M081" + - "M0810" + - "M0811" + - "M0812" + - "M0813" + - "M0814" + - "M0815" + - "M0816" + - "M0817" + - "M0818" + - "M0819" + - "M082" + - "M0820" + - "M0821" + - "M0822" + - "M0823" + - "M0824" + - "M0825" + - "M0826" + - "M0827" + - "M0828" + - "M0829" + - "M083" + - "M0830" + - "M0831" + - "M0832" + - "M0833" + - "M0834" + - "M0835" + - "M0836" + - "M0837" + - "M0838" + - "M0839" + - "M084" + - "M0840" + - "M0841" + - "M0842" + - "M0843" + - "M0844" + - "M0845" + - "M0846" + - "M0847" + - "M0848" + - "M0849" + - "M088" + - "M0880" + - "M0881" + - "M0882" + - "M0883" + - "M0884" + - "M0885" + - "M0886" + - "M0887" + - "M0888" + - "M0889" + - "M089" + - "M0890" + - "M0891" + - "M0892" + - "M0893" + - "M0894" + - "M0895" + - "M0896" + - "M0897" + - "M0898" + - "M0899" + - "M09" + - "M090" + - "M0900" + - "M0901" + - "M0902" + - "M0903" + - "M0904" + - "M0905" + - "M0906" + - "M0907" + - "M0908" + - "M0909" + - "M091" + - "M0910" + - "M0911" + - "M0912" + - "M0913" + - "M0914" + - "M0915" + - "M0916" + - "M0917" + - "M0918" + - "M0919" + - "M092" + - "M0920" + - "M0921" + - "M0922" + - "M0923" + - "M0924" + - "M0925" + - "M0926" + - "M0927" + - "M0928" + - "M0929" + - "M098" + - "M0980" + - "M0981" + - "M0982" + - "M0983" + - "M0984" + - "M0985" + - "M0986" + - "M0987" + - "M0988" + - "M0989" + - "M10" + - "M100" + - "M1000" + - "M1001" + - "M1002" + - "M1003" + - "M1004" + - "M1005" + - "M1006" + - "M1007" + - "M1008" + - "M1009" + - "M101" + - "M1010" + - "M1011" + - "M1012" + - "M1013" + - "M1014" + - "M1015" + - "M1016" + - "M1017" + - "M1018" + - "M1019" + - "M102" + - "M1020" + - "M1021" + - "M1022" + - "M1023" + - "M1024" + - "M1025" + - "M1026" + - "M1027" + - "M1028" + - "M1029" + - "M103" + - "M1030" + - "M1031" + - "M1032" + - "M1033" + - "M1034" + - "M1035" + - "M1036" + - "M1037" + - "M1038" + - "M1039" + - "M104" + - "M1040" + - "M1041" + - "M1042" + - "M1043" + - "M1044" + - "M1045" + - "M1046" + - "M1047" + - "M1048" + - "M1049" + - "M109" + - "M1090" + - "M1091" + - "M1092" + - "M1093" + - "M1094" + - "M1095" + - "M1096" + - "M1097" + - "M1098" + - "M1099" + - "M11" + - "M110" + - "M1100" + - "M1101" + - "M1102" + - "M1103" + - "M1104" + - "M1105" + - "M1106" + - "M1107" + - "M1108" + - "M1109" + - "M111" + - "M1110" + - "M1111" + - "M1112" + - "M1113" + - "M1114" + - "M1115" + - "M1116" + - "M1117" + - "M1118" + - "M1119" + - "M112" + - "M1120" + - "M1121" + - "M1122" + - "M1123" + - "M1124" + - "M1125" + - "M1126" + - "M1127" + - "M1128" + - "M1129" + - "M118" + - "M1180" + - "M1181" + - "M1182" + - "M1183" + - "M1184" + - "M1185" + - "M1186" + - "M1187" + - "M1188" + - "M1189" + - "M119" + - "M1190" + - "M1191" + - "M1192" + - "M1193" + - "M1194" + - "M1195" + - "M1196" + - "M1197" + - "M1198" + - "M1199" + - "M12" + - "M120" + - "M1200" + - "M1201" + - "M1202" + - "M1203" + - "M1204" + - "M1205" + - "M1206" + - "M1207" + - "M1208" + - "M1209" + - "M121" + - "M1210" + - "M1211" + - "M1212" + - "M1213" + - "M1214" + - "M1215" + - "M1216" + - "M1217" + - "M1218" + - "M1219" + - "M122" + - "M1220" + - "M1221" + - "M1222" + - "M1223" + - "M1224" + - "M1225" + - "M1226" + - "M1227" + - "M1228" + - "M1229" + - "M123" + - "M1230" + - "M1231" + - "M1232" + - "M1233" + - "M1234" + - "M1235" + - "M1236" + - "M1237" + - "M1238" + - "M1239" + - "M124" + - "M1240" + - "M1241" + - "M1242" + - "M1243" + - "M1244" + - "M1245" + - "M1246" + - "M1247" + - "M1248" + - "M1249" + - "M125" + - "M1250" + - "M1251" + - "M1252" + - "M1253" + - "M1254" + - "M1255" + - "M1256" + - "M1257" + - "M1258" + - "M1259" + - "M128" + - "M1280" + - "M1281" + - "M1282" + - "M1283" + - "M1284" + - "M1285" + - "M1286" + - "M1287" + - "M1288" + - "M1289" + - "M13" + - "M130" + - "M1300" + - "M1301" + - "M1302" + - "M1303" + - "M1304" + - "M1305" + - "M1306" + - "M1307" + - "M1308" + - "M1309" + - "M131" + - "M1310" + - "M1311" + - "M1312" + - "M1313" + - "M1314" + - "M1315" + - "M1316" + - "M1317" + - "M1318" + - "M1319" + - "M138" + - "M1380" + - "M1381" + - "M1382" + - "M1383" + - "M1384" + - "M1385" + - "M1386" + - "M1387" + - "M1388" + - "M1389" + - "M139" + - "M1390" + - "M1391" + - "M1392" + - "M1393" + - "M1394" + - "M1395" + - "M1396" + - "M1397" + - "M1398" + - "M1399" + - "M14" + - "M140" + - "M141" + - "M142" + - "M143" + - "M144" + - "M145" + - "M146" + - "M148" + - "M05" + - "M050" + - "M0500" + - "M0501" + - "M0502" + - "M0503" + - "M0504" + - "M0505" + - "M0506" + - "M0507" + - "M0508" + - "M0509" + - "M051" + - "M0510" + - "M0511" + - "M0512" + - "M0513" + - "M0514" + - "M0515" + - "M0516" + - "M0517" + - "M0518" + - "M0519" + - "M052" + - "M0520" + - "M0521" + - "M0522" + - "M0523" + - "M0524" + - "M0525" + - "M0526" + - "M0527" + - "M0528" + - "M0529" + - "M053" + - "M0530" + - "M0531" + - "M0532" + - "M0533" + - "M0534" + - "M0535" + - "M0536" + - "M0537" + - "M0538" + - "M0539" + - "M058" + - "M0580" + - "M0581" + - "M0582" + - "M0583" + - "M0584" + - "M0585" + - "M0586" + - "M0587" + - "M0588" + - "M0589" + - "M059" + - "M0590" + - "M0591" + - "M0592" + - "M0593" + - "M0594" + - "M0595" + - "M0596" + - "M0597" + - "M0598" + - "M0599" + - "M06" + - "M060" + - "M0600" + - "M0601" + - "M0602" + - "M0603" + - "M0604" + - "M0605" + - "M0606" + - "M0607" + - "M0608" + - "M0609" + - "M061" + - "M0610" + - "M0611" + - "M0612" + - "M0613" + - "M0614" + - "M0615" + - "M0616" + - "M0617" + - "M0618" + - "M0619" + - "M062" + - "M0620" + - "M0621" + - "M0622" + - "M0623" + - "M0624" + - "M0625" + - "M0626" + - "M0627" + - "M0628" + - "M0629" + - "M063" + - "M0630" + - "M0631" + - "M0632" + - "M0633" + - "M0634" + - "M0635" + - "M0636" + - "M0637" + - "M0638" + - "M0639" + - "M064" + - "M0640" + - "M0641" + - "M0642" + - "M0643" + - "M0644" + - "M0645" + - "M0646" + - "M0647" + - "M0648" + - "M0649" + - "M068" + - "M0680" + - "M0681" + - "M0682" + - "M0683" + - "M0684" + - "M0685" + - "M0686" + - "M0687" + - "M0688" + - "M0689" + - "M069" + - "M0690" + - "M0691" + - "M0692" + - "M0693" + - "M0694" + - "M0695" + - "M0696" + - "M0697" + - "M0698" + - "M0699" + - "M07" + - "M070" + - "M0700" + - "M0701" + - "M0702" + - "M0703" + - "M0704" + - "M0705" + - "M0706" + - "M0707" + - "M0708" + - "M0709" + - "M071" + - "M0710" + - "M0711" + - "M0712" + - "M0713" + - "M0714" + - "M0715" + - "M0716" + - "M0717" + - "M0718" + - "M0719" + - "M072" + - "M0720" + - "M0721" + - "M0722" + - "M0723" + - "M0724" + - "M0725" + - "M0726" + - "M0727" + - "M0728" + - "M0729" + - "M073" + - "M0730" + - "M0731" + - "M0732" + - "M0733" + - "M0734" + - "M0735" + - "M0736" + - "M0737" + - "M0738" + - "M0739" + - "M074" + - "M0740" + - "M0741" + - "M0742" + - "M0743" + - "M0744" + - "M0745" + - "M0746" + - "M0747" + - "M0748" + - "M0749" + - "M075" + - name: "G40-G47 Episodic and paroxysmal disorders" + codings: + - "G444" + - "G448" + - "G45" + - "G450" + - "G451" + - "G452" + - "G453" + - "G454" + - "G458" + - "G459" + - "G46" + - "G460" + - "G461" + - "G462" + - "G463" + - "G464" + - "G465" + - "G466" + - "G467" + - "G468" + - "G47" + - "G470" + - "G471" + - "G472" + - "G473" + - "G474" + - "G478" + - "G479" + - "G40" + - "G400" + - "G401" + - "G402" + - "G403" + - "G404" + - "G405" + - "G406" + - "G407" + - "G408" + - "G409" + - "G41" + - "G410" + - "G411" + - "G412" + - "G418" + - "G419" + - "G43" + - "G430" + - "G431" + - "G432" + - "G433" + - "G438" + - "G439" + - "G44" + - "G440" + - "G441" + - "G442" + - "G443" + - name: "G00-G09 Inflammatory diseases of the central nervous system" + codings: + - "G05" + - "G050" + - "G051" + - "G052" + - "G058" + - "G06" + - "G060" + - "G061" + - "G062" + - "G07" + - "G08" + - "G09" + - "G00" + - "G000" + - "G001" + - "G002" + - "G003" + - "G008" + - "G009" + - "G01" + - "G02" + - "G020" + - "G021" + - "G028" + - "G03" + - "G030" + - "G031" + - "G032" + - "G038" + - "G039" + - "G04" + - "G040" + - "G041" + - "G042" + - "G048" + - "G049" + - name: "J22 Unspecified acute lower respiratory infection" + codings: + - "J22" + - name: "O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium" + codings: + - "O10" + - "O100" + - "O101" + - "O102" + - "O103" + - "O104" + - "O109" + - "O11" + - "O12" + - "O120" + - "O121" + - "O122" + - "O13" + - "O14" + - "O140" + - "O141" + - "O142" + - "O149" + - "O15" + - "O150" + - "O151" + - "O152" + - "O159" + - "O16" + - name: "D73 Diseases of spleen" + codings: + - "D730" + - "D731" + - "D732" + - "D733" + - "D734" + - "D735" + - "D738" + - "D739" + - name: "D70 Agranulocytosis" + codings: + - "D70" + - name: "B25-B34 Other viral diseases" + codings: + - "B25" + - "B250" + - "B251" + - "B252" + - "B258" + - "B259" + - "B26" + - "B260" + - "B261" + - "B262" + - "B263" + - "B268" + - "B269" + - "B27" + - "B270" + - "B271" + - "B278" + - "B279" + - "B30" + - "B300" + - "B301" + - "B302" + - "B303" + - "B308" + - "B309" + - "B33" + - "B330" + - "B331" + - "B332" + - "B333" + - "B334" + - "B338" + - "B34" + - "B340" + - "B341" + - "B342" + - "B343" + - "B344" + - "B348" + - "B349" + - name: "D75 Other diseases of blood and blood-forming organs" + codings: + - "D751" + - "D752" + - "D758" + - "D759" + - "D750" + - name: "N92 Excessive, frequent and irregular menstruation" + codings: + - "N926" + - "N920" + - "N921" + - "N922" + - "N923" + - "N924" + - "N925" + - name: "N93 Other abnormal uterine and vaginal bleeding" + codings: + - "N930" + - "N938" + - "N939" + - name: "N90 Other noninflammatory disorders of vulva and perineum" + codings: + - "N900" + - "N901" + - "N902" + - "N903" + - "N904" + - "N905" + - "N906" + - "N907" + - "N908" + - "N909" + - name: "N97 Female infertility" + codings: + - "N970" + - "N971" + - "N972" + - "N973" + - "N974" + - "N978" + - "N979" + - name: "N94 Pain and other conditions associated with female genital organs and menstrual cycle" + codings: + - "N940" + - "N941" + - "N942" + - "N943" + - "N944" + - "N945" + - "N946" + - "N948" + - "N949" + - name: "N95 Menopausal and other perimenopausal disorders" + codings: + - "N950" + - "N951" + - "N952" + - "N953" + - "N958" + - "N959" + - name: "F05 Delirium, not induced by alcohol and other psychoactive substances" + codings: + - "F050" + - "F051" + - "F058" + - "F059" + - name: "D51 Vitamin B12 deficiency anaemia" + codings: + - "D518" + - "D519" + - "D510" + - "D511" + - "D512" + - "D513" + - name: "L20-L30 Dermatitis and eczema" + codings: + - "L249" + - "L25" + - "L250" + - "L251" + - "L252" + - "L253" + - "L254" + - "L255" + - "L258" + - "L259" + - "L26" + - "L27" + - "L270" + - "L271" + - "L272" + - "L278" + - "L279" + - "L28" + - "L280" + - "L281" + - "L282" + - "L29" + - "L290" + - "L291" + - "L292" + - "L293" + - "L298" + - "L299" + - "L30" + - "L300" + - "L301" + - "L302" + - "L303" + - "L304" + - "L305" + - "L308" + - "L309" + - "L20" + - "L200" + - "L208" + - "L209" + - "L21" + - "L210" + - "L211" + - "L218" + - "L219" + - "L22" + - "L23" + - "L230" + - "L231" + - "L232" + - "L233" + - "L234" + - "L235" + - "L236" + - "L237" + - "L238" + - "L239" + - "L24" + - "L240" + - "L241" + - "L242" + - "L243" + - "L244" + - "L245" + - "L246" + - "L247" + - "L248" + - name: "M70-M79 Other soft tissue disorders" + codings: + - "M70" + - "M700" + - "M7000" + - "M7001" + - "M7002" + - "M7003" + - "M7004" + - "M7005" + - "M7006" + - "M7007" + - "M7008" + - "M7009" + - "M701" + - "M7010" + - "M7011" + - "M7012" + - "M7013" + - "M7014" + - "M7015" + - "M7016" + - "M7017" + - "M7018" + - "M7019" + - "M702" + - "M7020" + - "M7021" + - "M7022" + - "M7023" + - "M7024" + - "M7025" + - "M7026" + - "M7027" + - "M7028" + - "M7029" + - "M703" + - "M7030" + - "M7031" + - "M7032" + - "M7033" + - "M7034" + - "M7035" + - "M7036" + - "M7037" + - "M7038" + - "M7039" + - "M704" + - "M7040" + - "M7041" + - "M7042" + - "M7043" + - "M7044" + - "M7045" + - "M7046" + - "M7047" + - "M7048" + - "M7049" + - "M705" + - "M7050" + - "M7051" + - "M7052" + - "M7053" + - "M7054" + - "M7055" + - "M7056" + - "M7057" + - "M7058" + - "M7059" + - "M706" + - "M7060" + - "M7061" + - "M7062" + - "M7063" + - "M7064" + - "M7065" + - "M7066" + - "M7067" + - "M7068" + - "M7069" + - "M707" + - "M7070" + - "M7071" + - "M7072" + - "M7073" + - "M7074" + - "M7075" + - "M7076" + - "M7077" + - "M7078" + - "M7079" + - "M708" + - "M7080" + - "M7081" + - "M7082" + - "M7083" + - "M7084" + - "M7085" + - "M7086" + - "M7087" + - "M7088" + - "M7089" + - "M709" + - "M7090" + - "M7091" + - "M7092" + - "M7093" + - "M7094" + - "M7095" + - "M7096" + - "M7097" + - "M7098" + - "M7099" + - "M71" + - "M710" + - "M7100" + - "M7101" + - "M7102" + - "M7103" + - "M7104" + - "M7105" + - "M7106" + - "M7107" + - "M7108" + - "M7109" + - "M711" + - "M7110" + - "M7111" + - "M7112" + - "M7113" + - "M7114" + - "M7115" + - "M7116" + - "M7117" + - "M7118" + - "M7119" + - "M712" + - "M7120" + - "M7121" + - "M7122" + - "M7123" + - "M7124" + - "M7125" + - "M7126" + - "M7127" + - "M7128" + - "M7129" + - "M713" + - "M7130" + - "M7131" + - "M7132" + - "M7133" + - "M7134" + - "M7135" + - "M7136" + - "M7137" + - "M7138" + - "M7139" + - "M714" + - "M7140" + - "M7141" + - "M7142" + - "M7143" + - "M7144" + - "M7145" + - "M7146" + - "M7147" + - "M7148" + - "M7149" + - "M715" + - "M7150" + - "M7151" + - "M7152" + - "M7153" + - "M7154" + - "M7155" + - "M7156" + - "M7157" + - "M7158" + - "M7159" + - "M718" + - "M7180" + - "M7181" + - "M7182" + - "M7183" + - "M7184" + - "M7185" + - "M7186" + - "M7187" + - "M7188" + - "M7189" + - "M719" + - "M7190" + - "M7191" + - "M7192" + - "M7193" + - "M7194" + - "M7195" + - "M7196" + - "M7197" + - "M7198" + - "M7199" + - "M72" + - "M720" + - "M7200" + - "M7201" + - "M7202" + - "M7203" + - "M7204" + - "M7205" + - "M7206" + - "M7207" + - "M7208" + - "M7209" + - "M721" + - "M7210" + - "M7211" + - "M7212" + - "M7213" + - "M7214" + - "M7215" + - "M7216" + - "M7217" + - "M7218" + - "M7219" + - "M722" + - "M7220" + - "M7221" + - "M7222" + - "M7223" + - "M7224" + - "M7225" + - "M7226" + - "M7227" + - "M7228" + - "M7229" + - "M723" + - "M7230" + - "M7231" + - "M7232" + - "M7233" + - "M7234" + - "M7235" + - "M7236" + - "M7237" + - "M7238" + - "M7239" + - "M724" + - "M7240" + - "M7241" + - "M7242" + - "M7243" + - "M7244" + - "M7245" + - "M7246" + - "M7247" + - "M7248" + - "M7249" + - "M725" + - "M7250" + - "M7251" + - "M7252" + - "M7253" + - "M7254" + - "M7255" + - "M7256" + - "M7257" + - "M7258" + - "M7259" + - "M726" + - "M7260" + - "M7261" + - "M7262" + - "M7263" + - "M7264" + - "M7265" + - "M7266" + - "M7267" + - "M7268" + - "M7269" + - "M728" + - "M7280" + - "M7281" + - "M7282" + - "M7283" + - "M7284" + - "M7285" + - "M7286" + - "M7287" + - "M7288" + - "M7289" + - "M729" + - "M7290" + - "M7291" + - "M7292" + - "M7293" + - "M7294" + - "M7295" + - "M7296" + - "M7297" + - "M7298" + - "M7299" + - "M73" + - "M730" + - "M7300" + - "M7301" + - "M7302" + - "M7303" + - "M7304" + - "M7305" + - "M7306" + - "M7307" + - "M7308" + - "M7309" + - "M731" + - "M7310" + - "M7311" + - "M7312" + - "M7313" + - "M7314" + - "M7315" + - "M7316" + - "M7317" + - "M7318" + - "M7319" + - "M738" + - "M7380" + - "M7381" + - "M7382" + - "M7383" + - "M7384" + - "M7385" + - "M7386" + - "M7387" + - "M7388" + - "M7389" + - "M75" + - "M750" + - "M751" + - "M752" + - "M753" + - "M754" + - "M755" + - "M758" + - "M7581" + - "M759" + - "M76" + - "M760" + - "M7600" + - "M7601" + - "M7602" + - "M7603" + - "M7604" + - "M7605" + - "M7606" + - "M7607" + - "M7608" + - "M7609" + - "M761" + - "M7610" + - "M7611" + - "M7612" + - "M7613" + - "M7614" + - "M7615" + - "M7616" + - "M7617" + - "M7618" + - "M7619" + - "M762" + - "M7620" + - "M7621" + - "M7622" + - "M7623" + - "M7624" + - "M7625" + - "M7626" + - "M7627" + - "M7628" + - "M7629" + - "M763" + - "M7630" + - "M7631" + - "M7632" + - "M7633" + - "M7634" + - "M7635" + - "M7636" + - "M7637" + - "M7638" + - "M7639" + - "M764" + - "M7640" + - "M7641" + - "M7642" + - "M7643" + - "M7644" + - "M7645" + - "M7646" + - "M7647" + - "M7648" + - "M7649" + - "M765" + - "M7650" + - "M7651" + - "M7652" + - "M7653" + - "M7654" + - "M7655" + - "M7656" + - "M7657" + - "M7658" + - "M7659" + - "M766" + - "M7660" + - "M7661" + - "M7662" + - "M7663" + - "M7664" + - "M7665" + - "M7666" + - "M7667" + - "M7668" + - "M7669" + - "M767" + - "M7670" + - "M7671" + - "M7672" + - "M7673" + - "M7674" + - "M7675" + - "M7676" + - "M7677" + - "M7678" + - "M7679" + - "M768" + - "M7680" + - "M7681" + - "M7682" + - "M7683" + - "M7684" + - "M7685" + - "M7686" + - "M7687" + - "M7688" + - "M7689" + - "M769" + - "M7690" + - "M7691" + - "M7692" + - "M7693" + - "M7694" + - "M7695" + - "M7696" + - "M7697" + - "M7698" + - "M7699" + - "M77" + - "M770" + - "M7700" + - "M7701" + - "M7702" + - "M7703" + - "M7704" + - "M7705" + - "M7706" + - "M7707" + - "M7708" + - "M7709" + - "M771" + - "M7710" + - "M7711" + - "M7712" + - "M7713" + - "M7714" + - "M7715" + - "M7716" + - "M7717" + - "M7718" + - "M7719" + - "M772" + - "M7720" + - "M7721" + - "M7722" + - "M7723" + - "M7724" + - "M7725" + - "M7726" + - "M7727" + - "M7728" + - "M7729" + - "M773" + - "M7730" + - "M7731" + - "M7732" + - "M7733" + - "M7734" + - "M7735" + - "M7736" + - "M7737" + - "M7738" + - "M7739" + - "M774" + - "M7740" + - "M7741" + - "M7742" + - "M7743" + - "M7744" + - "M7745" + - "M7746" + - "M7747" + - "M7748" + - "M7749" + - "M775" + - "M7750" + - "M7751" + - "M7752" + - "M7753" + - "M7754" + - "M7755" + - "M7756" + - "M7757" + - "M7758" + - "M7759" + - "M778" + - "M7780" + - "M7781" + - "M7782" + - "M7783" + - "M7784" + - "M7785" + - "M7786" + - "M7787" + - "M7788" + - "M7789" + - "M779" + - "M7790" + - "M7791" + - "M7792" + - "M7793" + - "M7794" + - "M7795" + - "M7796" + - "M7797" + - "M7798" + - "M7799" + - "M79" + - "M790" + - "M7900" + - "M7901" + - "M7902" + - "M7903" + - "M7904" + - "M7905" + - "M7906" + - "M7907" + - "M7908" + - "M7909" + - "M791" + - "M7910" + - "M7911" + - "M7912" + - "M7913" + - "M7914" + - "M7915" + - "M7916" + - "M7917" + - "M7918" + - "M7919" + - "M792" + - "M7920" + - "M7921" + - "M7922" + - "M7923" + - "M7924" + - "M7925" + - "M7926" + - "M7927" + - "M7928" + - "M7929" + - "M793" + - "M7930" + - "M7931" + - "M7932" + - "M7933" + - "M7934" + - "M7935" + - "M7936" + - "M7937" + - "M7938" + - "M7939" + - "M794" + - "M7940" + - "M7941" + - "M7942" + - "M7943" + - "M7944" + - "M7945" + - "M7946" + - "M7947" + - "M7948" + - "M7949" + - "M795" + - "M7950" + - "M7951" + - "M7952" + - "M7953" + - "M7954" + - "M7955" + - "M7956" + - "M7957" + - "M7958" + - "M7959" + - "M796" + - "M7960" + - "M7961" + - "M7962" + - "M7963" + - "M7964" + - "M7965" + - "M7966" + - "M7967" + - "M7968" + - "M7969" + - "M797" + - "M7970" + - "M7971" + - "M7972" + - "M7973" + - "M7974" + - "M7975" + - "M7976" + - "M7977" + - "M7978" + - "M7979" + - "M798" + - "M7980" + - "M7981" + - "M7982" + - "M7983" + - "M7984" + - "M7985" + - "M7986" + - "M7987" + - "M7988" + - "M7989" + - "M799" + - "M7990" + - "M7991" + - "M7992" + - "M7993" + - "M7994" + - "M7995" + - "M7996" + - "M7997" + - "M7998" + - "M7999" + - name: "I51 Complications and ill-defined descriptions of heart disease" + codings: + - "I514" + - "I515" + - "I516" + - "I517" + - "I518" + - "I519" + - "I510" + - "I511" + - "I512" + - "I513" + - name: "I50 Heart failure" + codings: + - "I500" + - "I501" + - "I509" + - name: "N03 Chronic nephritic syndrome" + codings: + - "N030" + - "N031" + - "N032" + - "N033" + - "N034" + - "N035" + - "N036" + - "N037" + - "N038" + - "N039" + - name: "N02 Recurrent and persistent haematuria" + codings: + - "N020" + - "N021" + - "N022" + - "N023" + - "N024" + - "N025" + - "N026" + - "N027" + - "N028" + - "N029" + - name: "H18 Other disorders of cornea" + codings: + - "H180" + - "H181" + - "H182" + - "H183" + - "H184" + - "H185" + - "H186" + - "H187" + - "H188" + - "H189" + - name: "M24 Other specific joint derangements" + codings: + - "M240" + - "M2400" + - "M2401" + - "M2402" + - "M2403" + - "M2404" + - "M2405" + - "M2406" + - "M2407" + - "M2408" + - "M2409" + - "M241" + - "M2410" + - "M2411" + - "M2412" + - "M2413" + - "M2414" + - "M2415" + - "M2416" + - "M2417" + - "M2418" + - "M2419" + - "M242" + - "M2420" + - "M2421" + - "M2422" + - "M2423" + - "M2424" + - "M2425" + - "M2426" + - "M2427" + - "M2428" + - "M2429" + - "M243" + - "M2430" + - "M2431" + - "M2432" + - "M2433" + - "M2434" + - "M2435" + - "M2436" + - "M2437" + - "M2438" + - "M2439" + - "M244" + - "M2440" + - "M2441" + - "M2442" + - "M2443" + - "M2444" + - "M2445" + - "M2446" + - "M2447" + - "M2448" + - "M2449" + - "M245" + - "M2450" + - "M2451" + - "M2452" + - "M2453" + - "M2454" + - "M2455" + - "M2456" + - "M2457" + - "M2458" + - "M2459" + - "M246" + - "M2460" + - "M2461" + - "M2462" + - "M2463" + - "M2464" + - "M2465" + - "M2466" + - "M2467" + - "M2468" + - "M2469" + - "M247" + - "M2470" + - "M2471" + - "M2472" + - "M2473" + - "M2474" + - "M2475" + - "M2476" + - "M2477" + - "M2478" + - "M2479" + - "M248" + - "M2480" + - "M2481" + - "M2482" + - "M2483" + - "M2484" + - "M2485" + - "M2486" + - "M2487" + - "M2488" + - "M2489" + - "M249" + - "M2490" + - "M2491" + - "M2492" + - "M2493" + - "M2494" + - "M2495" + - "M2496" + - "M2497" + - "M2498" + - "M2499" + - name: "H11 Other disorders of conjunctiva" + codings: + - "H110" + - "H111" + - "H112" + - "H113" + - "H114" + - "H118" + - "H119" + - name: "M20 Acquired deformities of fingers and toes" + codings: + - "M200" + - "M201" + - "M202" + - "M203" + - "M204" + - "M205" + - "M206" + - name: "M21 Other acquired deformities of limbs" + codings: + - "M2110" + - "M2111" + - "M2112" + - "M2113" + - "M2114" + - "M2115" + - "M2116" + - "M2117" + - "M2118" + - "M2119" + - "M212" + - "M2120" + - "M2121" + - "M2122" + - "M2123" + - "M2124" + - "M2125" + - "M2126" + - "M2127" + - "M2128" + - "M2129" + - "M213" + - "M2130" + - "M2131" + - "M2132" + - "M2133" + - "M2134" + - "M2135" + - "M2136" + - "M2137" + - "M2138" + - "M2139" + - "M214" + - "M2140" + - "M2141" + - "M2142" + - "M2143" + - "M2144" + - "M2145" + - "M2146" + - "M2147" + - "M2148" + - "M2149" + - "M215" + - "M2150" + - "M2151" + - "M2152" + - "M2153" + - "M2154" + - "M2155" + - "M2156" + - "M2157" + - "M2158" + - "M2159" + - "M216" + - "M2160" + - "M2161" + - "M2162" + - "M2163" + - "M2164" + - "M2165" + - "M2166" + - "M2167" + - "M2168" + - "M2169" + - "M217" + - "M2170" + - "M2171" + - "M2172" + - "M2173" + - "M2174" + - "M2175" + - "M2176" + - "M2177" + - "M2178" + - "M2179" + - "M218" + - "M2180" + - "M2181" + - "M2182" + - "M2183" + - "M2184" + - "M2185" + - "M2186" + - "M2187" + - "M2188" + - "M2189" + - "M219" + - "M2190" + - "M2191" + - "M2192" + - "M2193" + - "M2194" + - "M2195" + - "M2196" + - "M2197" + - "M2198" + - "M2199" + - "M210" + - "M2100" + - "M2101" + - "M2102" + - "M2103" + - "M2104" + - "M2105" + - "M2106" + - "M2107" + - "M2108" + - "M2109" + - "M211" + - name: "M22 Disorders of patella" + codings: + - "M220" + - "M221" + - "M2210" + - "M222" + - "M223" + - "M224" + - "M228" + - "M229" + - name: "M23 Internal derangement of knee" + codings: + - "M230" + - "M2300" + - "M2301" + - "M2302" + - "M2303" + - "M2304" + - "M2305" + - "M2306" + - "M2307" + - "M2309" + - "M231" + - "M2310" + - "M2311" + - "M2312" + - "M2313" + - "M2314" + - "M2315" + - "M2316" + - "M2317" + - "M2319" + - "M232" + - "M2320" + - "M2321" + - "M2322" + - "M2323" + - "M2324" + - "M2325" + - "M2326" + - "M2327" + - "M2329" + - "M233" + - "M2330" + - "M2331" + - "M2332" + - "M2333" + - "M2334" + - "M2335" + - "M2336" + - "M2337" + - "M2339" + - "M234" + - "M2340" + - "M2341" + - "M2342" + - "M2343" + - "M2344" + - "M2345" + - "M2346" + - "M2347" + - "M2349" + - "M235" + - "M2350" + - "M2351" + - "M2352" + - "M2353" + - "M2354" + - "M2355" + - "M2356" + - "M2357" + - "M2359" + - "M236" + - "M2360" + - "M2361" + - "M2362" + - "M2363" + - "M2364" + - "M2365" + - "M2366" + - "M2367" + - "M2369" + - "M238" + - "M2380" + - "M2381" + - "M2382" + - "M2383" + - "M2384" + - "M2385" + - "M2386" + - "M2387" + - "M2389" + - "M239" + - "M2390" + - "M2391" + - "M2392" + - "M2393" + - "M2394" + - "M2395" + - "M2396" + - "M2397" + - "M2399" + - name: "D65-D69 Coagulation defects, purpura and other haemorrhagic conditions" + codings: + - "D65" + - "D66" + - "D67" + - "D68" + - "D680" + - "D681" + - "D682" + - "D683" + - "D684" + - "D685" + - "D686" + - "D688" + - "D689" + - "D69" + - "D690" + - "D691" + - "D692" + - "D693" + - "D694" + - "D695" + - "D696" + - "D698" + - "D699" + - name: "D86 Sarcoidosis" + codings: + - "D860" + - "D861" + - "D862" + - "D863" + - "D868" + - "D869" + - name: "O60-O75 Complications of labour and delivery" + codings: + - "O60" + - "O600" + - "O601" + - "O602" + - "O603" + - "O61" + - "O610" + - "O611" + - "O618" + - "O619" + - "O62" + - "O620" + - "O621" + - "O622" + - "O623" + - "O624" + - "O628" + - "O629" + - "O63" + - "O630" + - "O631" + - "O632" + - "O639" + - "O64" + - "O640" + - "O641" + - "O642" + - "O643" + - "O644" + - "O645" + - "O648" + - "O649" + - "O65" + - "O650" + - "O651" + - "O652" + - "O653" + - "O654" + - "O655" + - "O658" + - "O659" + - "O66" + - "O660" + - "O661" + - "O662" + - "O663" + - "O664" + - "O665" + - "O668" + - "O669" + - "O67" + - "O670" + - "O678" + - "O679" + - "O68" + - "O680" + - "O681" + - "O682" + - "O683" + - "O688" + - "O689" + - "O69" + - "O690" + - "O691" + - "O692" + - "O693" + - "O694" + - "O695" + - "O698" + - "O699" + - "O70" + - "O700" + - "O701" + - "O702" + - "O703" + - "O709" + - "O71" + - "O710" + - "O711" + - "O712" + - "O713" + - "O714" + - "O715" + - "O716" + - "O717" + - "O718" + - "O719" + - "O72" + - "O720" + - "O721" + - "O722" + - "O723" + - "O73" + - "O730" + - "O731" + - "O74" + - "O740" + - "O741" + - "O742" + - "O743" + - "O744" + - "O745" + - "O746" + - "O747" + - "O748" + - "O749" + - "O75" + - "O750" + - "O751" + - "O752" + - "O753" + - "O754" + - "O755" + - "O756" + - "O757" + - "O758" + - "O759" + - name: "E50-E64 Other nutritional deficiencies" + codings: + - "E640" + - "E641" + - "E642" + - "E643" + - "E648" + - "E649" + - "E50" + - "E500" + - "E501" + - "E502" + - "E503" + - "E504" + - "E505" + - "E506" + - "E507" + - "E508" + - "E509" + - "E51" + - "E511" + - "E512" + - "E518" + - "E519" + - "E52" + - "E53" + - "E530" + - "E531" + - "E538" + - "E539" + - "E54" + - "E55" + - "E550" + - "E559" + - "E56" + - "E560" + - "E561" + - "E568" + - "E569" + - "E58" + - "E59" + - "E60" + - "E61" + - "E610" + - "E611" + - "E612" + - "E613" + - "E614" + - "E615" + - "E616" + - "E617" + - "E618" + - "E619" + - "E63" + - "E630" + - "E631" + - "E638" + - "E639" + - "E64" + - name: "J95-J99 Other diseases of the respiratory system" + codings: + - "J95" + - "J950" + - "J951" + - "J952" + - "J953" + - "J954" + - "J955" + - "J958" + - "J959" + - "J96" + - "J960" + - "J9600" + - "J9601" + - "J9609" + - "J961" + - "J9610" + - "J9611" + - "J9619" + - "J969" + - "J9690" + - "J9691" + - "J9699" + - "J98" + - "J980" + - "J981" + - "J982" + - "J983" + - "J984" + - "J985" + - "J986" + - "J988" + - "J989" + - "J99" + - "J990" + - "J991" + - "J998" + - name: "K90-K93 Other diseases of the digestive system" + codings: + - "K90" + - "K900" + - "K901" + - "K902" + - "K903" + - "K904" + - "K908" + - "K909" + - "K91" + - "K910" + - "K911" + - "K912" + - "K913" + - "K914" + - "K915" + - "K918" + - "K919" + - "K92" + - "K920" + - "K921" + - "K922" + - "K928" + - "K929" + - "K93" + - "K930" + - "K931" + - "K938" + - name: "E05 Thyrotoxicosis [hyperthyroidism]" + codings: + - "E050" + - "E051" + - "E052" + - "E053" + - "E054" + - "E055" + - "E058" + - "E059" + - name: "K35 Acute appendicitis" + codings: + - "K350" + - "K351" + - "K352" + - "K353" + - "K358" + - "K359" + - name: "B98 Other specified infectious agents as the cause of diseases classified to other chapters" + codings: + - "B980" + - "B981" + - name: "B96 Other bacterial agents as the cause of diseases classified to other chapters" + codings: + - "B960" + - "B961" + - "B962" + - "B963" + - "B964" + - "B965" + - "B966" + - "B967" + - "B968" + - name: "B97 Viral agents as the cause of diseases classified to other chapters" + codings: + - "B970" + - "B971" + - "B972" + - "B973" + - "B974" + - "B975" + - "B976" + - "B977" + - "B978" + - name: "B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters" + codings: + - "B950" + - "B951" + - "B952" + - "B953" + - "B954" + - "B955" + - "B956" + - "B957" + - "B958" + - name: "L00-L08 Infections of the skin and subcutaneous tissue" + codings: + - "L00" + - "L01" + - "L010" + - "L011" + - "L02" + - "L020" + - "L021" + - "L022" + - "L023" + - "L024" + - "L028" + - "L029" + - "L03" + - "L030" + - "L031" + - "L032" + - "L033" + - "L038" + - "L039" + - "L04" + - "L040" + - "L041" + - "L042" + - "L043" + - "L048" + - "L049" + - "L05" + - "L050" + - "L059" + - "L08" + - "L080" + - "L081" + - "L088" + - "L089" + - name: "K20-K31 Diseases of oesophagus, stomach and duodenum" + codings: + - "K20" + - "K21" + - "K210" + - "K219" + - "K22" + - "K220" + - "K221" + - "K222" + - "K223" + - "K224" + - "K225" + - "K226" + - "K227" + - "K228" + - "K229" + - "K23" + - "K230" + - "K231" + - "K238" + - "K25" + - "K250" + - "K251" + - "K252" + - "K253" + - "K254" + - "K255" + - "K256" + - "K257" + - "K259" + - "K26" + - "K260" + - "K261" + - "K262" + - "K263" + - "K264" + - "K265" + - "K266" + - "K267" + - "K269" + - "K27" + - "K270" + - "K271" + - "K272" + - "K273" + - "K274" + - "K275" + - "K276" + - "K277" + - "K279" + - "K28" + - "K280" + - "K281" + - "K282" + - "K283" + - "K284" + - "K285" + - "K286" + - "K287" + - "K289" + - "K29" + - "K290" + - "K291" + - "K292" + - "K293" + - "K294" + - "K295" + - "K296" + - "K297" + - "K298" + - "K299" + - "K30" + - "K31" + - "K310" + - "K311" + - "K312" + - "K313" + - "K314" + - "K315" + - "K316" + - "K317" + - "K318" + - "K319" + - name: "F10 Mental and behavioural disorders due to use of alcohol" + codings: + - "F100" + - "F101" + - "F102" + - "F103" + - "F104" + - "F105" + - "F106" + - "F107" + - "F108" + - "F109" + - name: "I69 Sequelae of cerebrovascular disease" + codings: + - "I690" + - "I691" + - "I692" + - "I693" + - "I694" + - "I698" + - name: "N30-N39 Other diseases of urinary system" + codings: + - "N33" + - "N330" + - "N338" + - "N34" + - "N340" + - "N341" + - "N342" + - "N343" + - "N35" + - "N350" + - "N351" + - "N358" + - "N359" + - "N36" + - "N360" + - "N361" + - "N362" + - "N363" + - "N368" + - "N369" + - "N37" + - "N370" + - "N378" + - "N39" + - "N390" + - "N391" + - "N392" + - "N393" + - "N394" + - "N398" + - "N399" + - "N30" + - "N300" + - "N301" + - "N302" + - "N303" + - "N304" + - "N308" + - "N309" + - "N31" + - "N310" + - "N311" + - "N312" + - "N318" + - "N319" + - "N32" + - "N320" + - "N321" + - "N322" + - "N323" + - "N324" + - "N328" + - "N329" + - name: "H25-H28 Disorders of lens" + codings: + - "H281" + - "H282" + - "H288" + - "H25" + - "H250" + - "H251" + - "H252" + - "H258" + - "H259" + - "H26" + - "H260" + - "H261" + - "H262" + - "H263" + - "H264" + - "H268" + - "H269" + - "H27" + - "H270" + - "H271" + - "H278" + - "H279" + - "H28" + - "H280" + - name: "I74 Arterial embolism and thrombosis" + codings: + - "I742" + - "I743" + - "I744" + - "I745" + - "I748" + - "I749" + - "I740" + - "I741" + - name: "I72 Other aneurysm" + codings: + - "I720" + - "I721" + - "I722" + - "I723" + - "I724" + - "I725" + - "I726" + - "I728" + - "I729" + - name: "L43 Lichen planus" + codings: + - "L430" + - "L431" + - "L432" + - "L433" + - "L438" + - "L439" + - name: "E27 Other disorders of adrenal gland" + codings: + - "E270" + - "E271" + - "E272" + - "E273" + - "E274" + - "E275" + - "E278" + - "E279" + - name: "A00-A09 Intestinal infectious diseases" + codings: + - "A00" + - "A000" + - "A001" + - "A009" + - "A01" + - "A010" + - "A011" + - "A012" + - "A013" + - "A014" + - "A02" + - "A020" + - "A021" + - "A022" + - "A028" + - "A029" + - "A03" + - "A030" + - "A031" + - "A032" + - "A033" + - "A038" + - "A039" + - "A04" + - "A040" + - "A041" + - "A042" + - "A043" + - "A044" + - "A045" + - "A046" + - "A047" + - "A048" + - "A049" + - "A05" + - "A050" + - "A051" + - "A052" + - "A053" + - "A054" + - "A058" + - "A059" + - "A06" + - "A060" + - "A061" + - "A062" + - "A063" + - "A064" + - "A065" + - "A066" + - "A067" + - "A068" + - "A069" + - "A07" + - "A070" + - "A071" + - "A072" + - "A073" + - "A078" + - "A079" + - "A08" + - "A080" + - "A081" + - "A082" + - "A083" + - "A084" + - "A085" + - "A09" + - "A090" + - "A099" + - name: "E21 Hyperparathyroidism and other disorders of parathyroid gland" + codings: + - "E210" + - "E211" + - "E212" + - "E213" + - "E214" + - "E215" + - name: "O80 Single spontaneous delivery" + codings: + - "O800" + - "O801" + - "O808" + - "O809" + - name: "O82 Single delivery by Caesarean section" + codings: + - "O828" + - "O829" + - "O820" + - "O821" + - "O822" + - name: "H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction" + codings: + - "H527" + - "H49" + - "H490" + - "H491" + - "H492" + - "H493" + - "H494" + - "H498" + - "H499" + - "H50" + - "H500" + - "H501" + - "H502" + - "H503" + - "H504" + - "H505" + - "H506" + - "H508" + - "H509" + - "H51" + - "H510" + - "H511" + - "H512" + - "H518" + - "H519" + - "H52" + - "H520" + - "H521" + - "H522" + - "H523" + - "H524" + - "H525" + - "H526" + - name: "G20-G26 Extrapyramidal and movement disorders" + codings: + - "G20" + - "G21" + - "G210" + - "G211" + - "G212" + - "G213" + - "G214" + - "G218" + - "G219" + - "G22" + - "G23" + - "G230" + - "G231" + - "G232" + - "G233" + - "G238" + - "G239" + - "G24" + - "G240" + - "G241" + - "G242" + - "G243" + - "G244" + - "G245" + - "G248" + - "G249" + - "G25" + - "G250" + - "G251" + - "G252" + - "G253" + - "G254" + - "G255" + - "G256" + - "G258" + - "G259" + - "G26" + - name: "O16 Unspecified maternal hypertension" + codings: + - "O16" + - name: "M91-M94 Chondropathies" + codings: + - "M91" + - "M910" + - "M9100" + - "M9101" + - "M9102" + - "M9103" + - "M9104" + - "M9105" + - "M9106" + - "M9107" + - "M9108" + - "M9109" + - "M911" + - "M9110" + - "M9111" + - "M9112" + - "M9113" + - "M9114" + - "M9115" + - "M9116" + - "M9117" + - "M9118" + - "M9119" + - "M912" + - "M9120" + - "M9121" + - "M9122" + - "M9123" + - "M9124" + - "M9125" + - "M9126" + - "M9127" + - "M9128" + - "M9129" + - "M913" + - "M9130" + - "M9131" + - "M9132" + - "M9133" + - "M9134" + - "M9135" + - "M9136" + - "M9137" + - "M9138" + - "M9139" + - "M918" + - "M9180" + - "M9181" + - "M9182" + - "M9183" + - "M9184" + - "M9185" + - "M9186" + - "M9187" + - "M9188" + - "M9189" + - "M919" + - "M9190" + - "M9191" + - "M9192" + - "M9193" + - "M9194" + - "M9195" + - "M9196" + - "M9197" + - "M9198" + - "M9199" + - "M92" + - "M920" + - "M921" + - "M9210" + - "M922" + - "M923" + - "M924" + - "M925" + - "M9250" + - "M9251" + - "M926" + - "M927" + - "M928" + - "M929" + - "M93" + - "M930" + - "M931" + - "M932" + - "M9326" + - "M938" + - "M9386" + - "M939" + - "M94" + - "M940" + - "M9400" + - "M9401" + - "M9402" + - "M9403" + - "M9404" + - "M9405" + - "M9406" + - "M9407" + - "M9408" + - "M9409" + - "M941" + - "M9410" + - "M9411" + - "M9412" + - "M9413" + - "M9414" + - "M9415" + - "M9416" + - "M9417" + - "M9418" + - "M9419" + - "M942" + - "M9420" + - "M9421" + - "M9422" + - "M9423" + - "M9424" + - "M9425" + - "M9426" + - "M9427" + - "M9428" + - "M9429" + - "M943" + - "M9430" + - "M9431" + - "M9432" + - "M9433" + - "M9434" + - "M9435" + - "M9436" + - "M9437" + - "M9438" + - "M9439" + - "M948" + - "M9480" + - "M9481" + - "M9482" + - "M9483" + - "M9484" + - "M9485" + - "M9486" + - "M9487" + - "M9488" + - "M9489" + - "M949" + - "M9490" + - "M9491" + - "M9492" + - "M9493" + - "M9494" + - "M9495" + - "M9496" + - "M9497" + - "M9498" + - "M9499" + - name: "D50-D53 Nutritional anaemias" + codings: + - "D50" + - "D500" + - "D501" + - "D508" + - "D509" + - "D51" + - "D510" + - "D511" + - "D512" + - "D513" + - "D518" + - "D519" + - "D52" + - "D520" + - "D521" + - "D528" + - "D529" + - "D53" + - "D530" + - "D531" + - "D532" + - "D538" + - "D539" + - name: "K00-K14 Diseases of oral cavity, salivary glands and jaws" + codings: + - "K00" + - "K000" + - "K001" + - "K002" + - "K003" + - "K004" + - "K005" + - "K006" + - "K007" + - "K008" + - "K009" + - "K01" + - "K010" + - "K011" + - "K02" + - "K020" + - "K021" + - "K022" + - "K023" + - "K024" + - "K025" + - "K028" + - "K029" + - "K03" + - "K030" + - "K031" + - "K032" + - "K033" + - "K034" + - "K035" + - "K036" + - "K037" + - "K038" + - "K039" + - "K04" + - "K040" + - "K041" + - "K042" + - "K043" + - "K044" + - "K045" + - "K046" + - "K047" + - "K048" + - "K049" + - "K05" + - "K050" + - "K051" + - "K052" + - "K0522" + - "K053" + - "K054" + - "K055" + - "K056" + - "K06" + - "K060" + - "K061" + - "K062" + - "K068" + - "K069" + - "K07" + - "K070" + - "K071" + - "K072" + - "K073" + - "K074" + - "K075" + - "K076" + - "K078" + - "K079" + - "K08" + - "K080" + - "K081" + - "K082" + - "K083" + - "K088" + - "K089" + - "K09" + - "K090" + - "K091" + - "K092" + - "K098" + - "K099" + - "K10" + - "K100" + - "K101" + - "K102" + - "K103" + - "K108" + - "K109" + - "K11" + - "K110" + - "K111" + - "K112" + - "K113" + - "K114" + - "K115" + - "K116" + - "K117" + - "K118" + - "K119" + - "K12" + - "K120" + - "K121" + - "K122" + - "K123" + - "K13" + - "K130" + - "K131" + - "K132" + - "K1329" + - "K133" + - "K134" + - "K135" + - "K136" + - "K137" + - "K14" + - "K140" + - "K141" + - "K142" + - "K143" + - "K144" + - "K145" + - "K146" + - "K148" + - "K149" + - name: "L30 Other dermatitis" + codings: + - "L303" + - "L304" + - "L305" + - "L308" + - "L309" + - "L300" + - "L301" + - "L302" + - name: "M60-M63 Disorders of muscles" + codings: + - "M60" + - "M600" + - "M6000" + - "M6001" + - "M6002" + - "M6003" + - "M6004" + - "M6005" + - "M6006" + - "M6007" + - "M6008" + - "M6009" + - "M601" + - "M6010" + - "M6011" + - "M6012" + - "M6013" + - "M6014" + - "M6015" + - "M6016" + - "M6017" + - "M6018" + - "M6019" + - "M602" + - "M6020" + - "M6021" + - "M6022" + - "M6023" + - "M6024" + - "M6025" + - "M6026" + - "M6027" + - "M6028" + - "M6029" + - "M608" + - "M6080" + - "M6081" + - "M6082" + - "M6083" + - "M6084" + - "M6085" + - "M6086" + - "M6087" + - "M6088" + - "M6089" + - "M609" + - "M6090" + - "M6091" + - "M6092" + - "M6093" + - "M6094" + - "M6095" + - "M6096" + - "M6097" + - "M6098" + - "M6099" + - "M61" + - "M610" + - "M6100" + - "M6101" + - "M6102" + - "M6103" + - "M6104" + - "M6105" + - "M6106" + - "M6107" + - "M6108" + - "M6109" + - "M611" + - "M6110" + - "M6111" + - "M6112" + - "M6113" + - "M6114" + - "M6115" + - "M6116" + - "M6117" + - "M6118" + - "M6119" + - "M612" + - "M6120" + - "M6121" + - "M6122" + - "M6123" + - "M6124" + - "M6125" + - "M6126" + - "M6127" + - "M6128" + - "M6129" + - "M613" + - "M6130" + - "M6131" + - "M6132" + - "M6133" + - "M6134" + - "M6135" + - "M6136" + - "M6137" + - "M6138" + - "M6139" + - "M614" + - "M6140" + - "M6141" + - "M6142" + - "M6143" + - "M6144" + - "M6145" + - "M6146" + - "M6147" + - "M6148" + - "M6149" + - "M615" + - "M6150" + - "M6151" + - "M6152" + - "M6153" + - "M6154" + - "M6155" + - "M6156" + - "M6157" + - "M6158" + - "M6159" + - "M619" + - "M6190" + - "M6191" + - "M6192" + - "M6193" + - "M6194" + - "M6195" + - "M6196" + - "M6197" + - "M6198" + - "M6199" + - "M62" + - "M620" + - "M6200" + - "M6201" + - "M6202" + - "M6203" + - "M6204" + - "M6205" + - "M6206" + - "M6207" + - "M6208" + - "M6209" + - "M621" + - "M6210" + - "M6211" + - "M6212" + - "M6213" + - "M6214" + - "M6215" + - "M6216" + - "M6217" + - "M6218" + - "M6219" + - "M622" + - "M6220" + - "M6221" + - "M6222" + - "M6223" + - "M6224" + - "M6225" + - "M6226" + - "M6227" + - "M6228" + - "M6229" + - "M623" + - "M6230" + - "M6231" + - "M6232" + - "M6233" + - "M6234" + - "M6235" + - "M6236" + - "M6237" + - "M6238" + - "M6239" + - "M624" + - "M6240" + - "M6241" + - "M6242" + - "M6243" + - "M6244" + - "M6245" + - "M6246" + - "M6247" + - "M6248" + - "M6249" + - "M625" + - "M6250" + - "M6251" + - "M6252" + - "M6253" + - "M6254" + - "M6255" + - "M6256" + - "M6257" + - "M6258" + - "M6259" + - "M626" + - "M6260" + - "M6261" + - "M6262" + - "M6263" + - "M6264" + - "M6265" + - "M6266" + - "M6267" + - "M6268" + - "M6269" + - "M628" + - "M6280" + - "M6281" + - "M6282" + - "M6283" + - "M6284" + - "M6285" + - "M6286" + - "M6287" + - "M6288" + - "M6289" + - "M629" + - "M6290" + - "M6291" + - "M6292" + - "M6293" + - "M6294" + - "M6295" + - "M6296" + - "M6297" + - "M6298" + - "M6299" + - "M63" + - "M630" + - "M631" + - "M632" + - "M633" + - "M638" + - name: "F41 Other anxiety disorders" + codings: + - "F411" + - "F412" + - "F413" + - "F418" + - "F419" + - "F410" + - name: "F40 Phobic anxiety disorders" + codings: + - "F400" + - "F401" + - "F402" + - "F408" + - "F409" + - name: "F43 Reaction to severe stress, and adjustment disorders" + codings: + - "F439" + - "F430" + - "F431" + - "F432" + - "F438" + - name: "K31 Other diseases of stomach and duodenum" + codings: + - "K310" + - "K311" + - "K312" + - "K313" + - "K314" + - "K315" + - "K316" + - "K317" + - "K318" + - "K319" + - name: "K30 Dyspepsia" + codings: + - "K30" + - name: "M48 Other spondylopathies" + codings: + - "M480" + - "M4800" + - "M4801" + - "M4802" + - "M4803" + - "M4804" + - "M4805" + - "M4806" + - "M4807" + - "M4808" + - "M4809" + - "M481" + - "M4810" + - "M4811" + - "M4812" + - "M4813" + - "M4814" + - "M4815" + - "M4816" + - "M4817" + - "M4818" + - "M4819" + - "M482" + - "M4820" + - "M4821" + - "M4822" + - "M4823" + - "M4824" + - "M4825" + - "M4826" + - "M4827" + - "M4828" + - "M4829" + - "M483" + - "M4830" + - "M4831" + - "M4832" + - "M4833" + - "M4834" + - "M4835" + - "M4836" + - "M4837" + - "M4838" + - "M4839" + - "M484" + - "M4840" + - "M4841" + - "M4842" + - "M4843" + - "M4844" + - "M4845" + - "M4846" + - "M4847" + - "M4848" + - "M4849" + - "M485" + - "M4850" + - "M4851" + - "M4852" + - "M4853" + - "M4854" + - "M4855" + - "M4856" + - "M4857" + - "M4858" + - "M4859" + - "M488" + - "M4880" + - "M4881" + - "M4882" + - "M4883" + - "M4884" + - "M4885" + - "M4886" + - "M4887" + - "M4888" + - "M4889" + - "M489" + - "M4890" + - "M4891" + - "M4892" + - "M4893" + - "M4894" + - "M4895" + - "M4896" + - "M4897" + - "M4898" + - "M4899" + - name: "N48 Other disorders of penis" + codings: + - "N485" + - "N486" + - "N488" + - "N489" + - "N480" + - "N481" + - "N482" + - "N483" + - "N484" + - name: "N41 Inflammatory diseases of prostate" + codings: + - "N410" + - "N411" + - "N412" + - "N413" + - "N418" + - "N419" + - name: "N40 Hyperplasia of prostate" + codings: + - "N40" + - name: "N43 Hydrocele and spermatocele" + codings: + - "N431" + - "N432" + - "N433" + - "N434" + - "N430" + - name: "N42 Other disorders of prostate" + codings: + - "N420" + - "N421" + - "N422" + - "N423" + - "N428" + - "N429" + - name: "N45 Orchitis and epididymitis" + codings: + - "N450" + - "N459" + - name: "N47 Redundant prepuce, phimosis and paraphimosis" + codings: + - "N47" + - name: "K80 Cholelithiasis" + codings: + - "K805" + - "K808" + - "K800" + - "K801" + - "K802" + - "K803" + - "K8036" + - "K804" + - name: "B95-B98 Bacterial, viral and other infectious agents" + codings: + - "B95" + - "B950" + - "B951" + - "B952" + - "B953" + - "B954" + - "B955" + - "B956" + - "B957" + - "B958" + - "B96" + - "B960" + - "B961" + - "B962" + - "B963" + - "B964" + - "B965" + - "B966" + - "B967" + - "B968" + - "B97" + - "B970" + - "B971" + - "B972" + - "B973" + - "B974" + - "B975" + - "B976" + - "B977" + - "B978" + - "B98" + - "B980" + - "B981" + - name: "K82 Other diseases of gallbladder" + codings: + - "K820" + - "K821" + - "K822" + - "K823" + - "K824" + - "K828" + - "K829" + - name: "K83 Other diseases of biliary tract" + codings: + - "K830" + - "K831" + - "K832" + - "K833" + - "K834" + - "K835" + - "K838" + - "K839" + - name: "K85 Acute pancreatitis" + codings: + - "K850" + - "K851" + - "K852" + - "K853" + - "K858" + - "K859" + - name: "K86 Other diseases of pancreas" + codings: + - "K860" + - "K861" + - "K862" + - "K863" + - "K868" + - "K869" + - name: "K76 Other diseases of liver" + codings: + - "K760" + - "K761" + - "K762" + - "K763" + - "K764" + - "K765" + - "K766" + - "K767" + - "K768" + - "K769" + - name: "A08 Viral and other specified intestinal infections" + codings: + - "A085" + - "A080" + - "A081" + - "A082" + - "A083" + - "A084" + - name: "A09 Diarrhoea and gastro-enteritis of presumed infectious origin" + codings: + - "A090" + - "A099" + - name: "J20-J22 Other acute lower respiratory infections" + codings: + - "J20" + - "J200" + - "J201" + - "J202" + - "J203" + - "J204" + - "J205" + - "J206" + - "J207" + - "J208" + - "J209" + - "J21" + - "J210" + - "J211" + - "J218" + - "J219" + - "J22" + - name: "A04 Other bacterial intestinal infections" + codings: + - "A040" + - "A041" + - "A042" + - "A043" + - "A044" + - "A045" + - "A046" + - "A047" + - "A048" + - "A049" + - name: "I08 Multiple valve diseases" + codings: + - "I080" + - "I081" + - "I082" + - "I083" + - "I088" + - "I089" + - name: "K65-K67 Diseases of peritoneum" + codings: + - "K65" + - "K650" + - "K658" + - "K659" + - "K66" + - "K660" + - "K661" + - "K668" + - "K669" + - "K67" + - "K670" + - "K671" + - "K672" + - "K673" + - "K678" + - name: "K55-K64 Other diseases of intestines" + codings: + - "K631" + - "K632" + - "K633" + - "K634" + - "K635" + - "K638" + - "K639" + - "K64" + - "K640" + - "K641" + - "K642" + - "K643" + - "K644" + - "K645" + - "K648" + - "K649" + - "K55" + - "K550" + - "K551" + - "K552" + - "K558" + - "K559" + - "K56" + - "K560" + - "K561" + - "K562" + - "K563" + - "K564" + - "K565" + - "K566" + - "K567" + - "K57" + - "K570" + - "K571" + - "K572" + - "K573" + - "K574" + - "K575" + - "K578" + - "K579" + - "K58" + - "K580" + - "K589" + - "K59" + - "K590" + - "K591" + - "K592" + - "K593" + - "K594" + - "K598" + - "K599" + - "K60" + - "K600" + - "K601" + - "K602" + - "K603" + - "K604" + - "K605" + - "K61" + - "K610" + - "K611" + - "K612" + - "K613" + - "K614" + - "K62" + - "K620" + - "K621" + - "K622" + - "K623" + - "K624" + - "K625" + - "K626" + - "K627" + - "K628" + - "K629" + - "K63" + - "K630" + - name: "M51 Other intervertebral disk disorders" + codings: + - "M510" + - "M511" + - "M5116" + - "M5119" + - "M512" + - "M513" + - "M5137" + - "M514" + - "M518" + - "M519" + - name: "M50 Cervical disk disorders" + codings: + - "M501" + - "M502" + - "M503" + - "M508" + - "M509" + - "M500" + - name: "M53 Other dorsopathies, not elsewhere classified" + codings: + - "M5382" + - "M5383" + - "M5384" + - "M5385" + - "M5386" + - "M5387" + - "M5388" + - "M5389" + - "M539" + - "M5390" + - "M5391" + - "M5392" + - "M5393" + - "M5394" + - "M5395" + - "M5396" + - "M5397" + - "M5398" + - "M5399" + - "M530" + - "M5300" + - "M5301" + - "M5302" + - "M5303" + - "M5304" + - "M5305" + - "M5306" + - "M5307" + - "M5308" + - "M5309" + - "M531" + - "M5310" + - "M5311" + - "M5312" + - "M5313" + - "M5314" + - "M5315" + - "M5316" + - "M5317" + - "M5318" + - "M5319" + - "M532" + - "M5320" + - "M5321" + - "M5322" + - "M5323" + - "M5324" + - "M5325" + - "M5326" + - "M5327" + - "M5328" + - "M5329" + - "M533" + - "M5330" + - "M5331" + - "M5332" + - "M5333" + - "M5334" + - "M5335" + - "M5336" + - "M5337" + - "M5338" + - "M5339" + - "M538" + - "M5380" + - "M5381" + - name: "H55-H59 Other disorders of eye and adnexa" + codings: + - "H59" + - "H590" + - "H598" + - "H599" + - "H55" + - "H57" + - "H570" + - "H571" + - "H578" + - "H579" + - "H58" + - "H580" + - "H581" + - "H588" + - "H589" + - name: "M07 Psoriatic and enteropathic arthropathies" + codings: + - "M0750" + - "M0751" + - "M0752" + - "M0753" + - "M0754" + - "M0755" + - "M0756" + - "M0757" + - "M0758" + - "M0759" + - "M076" + - "M0760" + - "M0761" + - "M0762" + - "M0763" + - "M0764" + - "M0765" + - "M0766" + - "M0767" + - "M0768" + - "M0769" + - "M070" + - "M0700" + - "M0701" + - "M0702" + - "M0703" + - "M0704" + - "M0705" + - "M0706" + - "M0707" + - "M0708" + - "M0709" + - "M071" + - "M0710" + - "M0711" + - "M0712" + - "M0713" + - "M0714" + - "M0715" + - "M0716" + - "M0717" + - "M0718" + - "M0719" + - "M072" + - "M0720" + - "M0721" + - "M0722" + - "M0723" + - "M0724" + - "M0725" + - "M0726" + - "M0727" + - "M0728" + - "M0729" + - "M073" + - "M0730" + - "M0731" + - "M0732" + - "M0733" + - "M0734" + - "M0735" + - "M0736" + - "M0737" + - "M0738" + - "M0739" + - "M074" + - "M0740" + - "M0741" + - "M0742" + - "M0743" + - "M0744" + - "M0745" + - "M0746" + - "M0747" + - "M0748" + - "M0749" + - "M075" + - name: "H43-H45 Disorders of vitreous body and globe" + codings: + - "H43" + - "H430" + - "H431" + - "H432" + - "H433" + - "H438" + - "H439" + - "H44" + - "H440" + - "H441" + - "H442" + - "H443" + - "H444" + - "H445" + - "H446" + - "H447" + - "H448" + - "H449" + - "H45" + - "H450" + - "H451" + - "H458" + - name: "H54 Blindness and low vision" + codings: + - "H540" + - "H541" + - "H542" + - "H543" + - "H544" + - "H545" + - "H546" + - "H547" + - "H549" + - name: "L80-L99 Other disorders of the skin and subcutaneous tissue" + codings: + - "L901" + - "L902" + - "L903" + - "L904" + - "L905" + - "L906" + - "L908" + - "L909" + - "L91" + - "L910" + - "L918" + - "L919" + - "L92" + - "L920" + - "L921" + - "L922" + - "L923" + - "L928" + - "L929" + - "L93" + - "L930" + - "L931" + - "L932" + - "L94" + - "L940" + - "L941" + - "L942" + - "L943" + - "L944" + - "L945" + - "L946" + - "L948" + - "L949" + - "L95" + - "L950" + - "L951" + - "L958" + - "L959" + - "L97" + - "L98" + - "L980" + - "L981" + - "L982" + - "L983" + - "L984" + - "L985" + - "L986" + - "L987" + - "L988" + - "L989" + - "L99" + - "L990" + - "L998" + - "L80" + - "L81" + - "L810" + - "L811" + - "L812" + - "L813" + - "L814" + - "L815" + - "L816" + - "L817" + - "L818" + - "L819" + - "L82" + - "L83" + - "L84" + - "L85" + - "L850" + - "L851" + - "L852" + - "L853" + - "L858" + - "L859" + - "L86" + - "L87" + - "L870" + - "L871" + - "L872" + - "L878" + - "L879" + - "L88" + - "L89" + - "L890" + - "L891" + - "L892" + - "L893" + - "L899" + - "L90" + - "L900" + - name: "H50 Other strabismus" + codings: + - "H500" + - "H501" + - "H502" + - "H503" + - "H504" + - "H505" + - "H506" + - "H508" + - "H509" + - name: "H52 Disorders of refraction and accommodation" + codings: + - "H527" + - "H520" + - "H521" + - "H522" + - "H523" + - "H524" + - "H525" + - "H526" + - name: "H53 Visual disturbances" + codings: + - "H530" + - "H531" + - "H532" + - "H533" + - "H534" + - "H535" + - "H536" + - "H538" + - "H539" + - name: "I30-I52 Other forms of heart disease" + codings: + - "I30" + - "I300" + - "I301" + - "I308" + - "I309" + - "I31" + - "I310" + - "I311" + - "I312" + - "I313" + - "I318" + - "I319" + - "I32" + - "I320" + - "I321" + - "I328" + - "I33" + - "I330" + - "I339" + - "I34" + - "I340" + - "I341" + - "I342" + - "I348" + - "I349" + - "I35" + - "I350" + - "I351" + - "I352" + - "I358" + - "I359" + - "I36" + - "I360" + - "I361" + - "I362" + - "I368" + - "I369" + - "I37" + - "I370" + - "I371" + - "I372" + - "I378" + - "I379" + - "I38" + - "I39" + - "I390" + - "I391" + - "I392" + - "I393" + - "I394" + - "I398" + - "I40" + - "I400" + - "I401" + - "I408" + - "I409" + - "I41" + - "I410" + - "I411" + - "I412" + - "I418" + - "I42" + - "I420" + - "I421" + - "I422" + - "I423" + - "I424" + - "I425" + - "I426" + - "I427" + - "I428" + - "I429" + - "I43" + - "I430" + - "I431" + - "I432" + - "I438" + - "I44" + - "I440" + - "I441" + - "I442" + - "I443" + - "I444" + - "I445" + - "I446" + - "I447" + - "I45" + - "I450" + - "I451" + - "I452" + - "I453" + - "I454" + - "I455" + - "I456" + - "I458" + - "I459" + - "I46" + - "I460" + - "I461" + - "I469" + - "I47" + - "I470" + - "I471" + - "I472" + - "I479" + - "I48" + - "I480" + - "I481" + - "I482" + - "I483" + - "I484" + - "I489" + - "I49" + - "I490" + - "I491" + - "I492" + - "I493" + - "I494" + - "I495" + - "I498" + - "I499" + - "I50" + - "I500" + - "I501" + - "I509" + - "I51" + - "I510" + - "I511" + - "I512" + - "I513" + - "I514" + - "I515" + - "I516" + - "I517" + - "I518" + - "I519" + - "I52" + - "I520" + - "I521" + - "I528" + - name: "L08 Other local infections of skin and subcutaneous tissue" + codings: + - "L080" + - "L081" + - "L088" + - "L089" + - name: "H90-H95 Other disorders of ear" + codings: + - "H90" + - "H900" + - "H901" + - "H902" + - "H903" + - "H904" + - "H905" + - "H906" + - "H907" + - "H908" + - "H91" + - "H910" + - "H911" + - "H912" + - "H913" + - "H918" + - "H919" + - "H92" + - "H920" + - "H921" + - "H922" + - "H93" + - "H930" + - "H931" + - "H932" + - "H933" + - "H938" + - "H939" + - "H94" + - "H940" + - "H948" + - "H95" + - "H950" + - "H951" + - "H958" + - "H959" + - name: "L05 Pilonidal cyst" + codings: + - "L059" + - "L050" + - name: "L03 Cellulitis" + codings: + - "L030" + - "L031" + - "L032" + - "L033" + - "L038" + - "L039" + - name: "J90-J94 Other diseases of pleura" + codings: + - "J948" + - "J949" + - "J90" + - "J91" + - "J92" + - "J920" + - "J929" + - "J93" + - "J930" + - "J931" + - "J938" + - "J939" + - "J94" + - "J940" + - "J941" + - "J942" + - name: "D70-D77 Other diseases of blood and blood-forming organs" + codings: + - "D70" + - "D71" + - "D72" + - "D720" + - "D721" + - "D728" + - "D729" + - "D73" + - "D730" + - "D731" + - "D732" + - "D733" + - "D734" + - "D735" + - "D738" + - "D739" + - "D74" + - "D740" + - "D748" + - "D749" + - "D75" + - "D750" + - "D751" + - "D752" + - "D758" + - "D759" + - "D76" + - "D760" + - "D761" + - "D762" + - "D763" + - "D77" + - name: "K81 Cholecystitis" + codings: + - "K810" + - "K811" + - "K818" + - "K819" + - name: "J09-J18 Influenza and pneumonia" + codings: + - "J09" + - "J10" + - "J100" + - "J101" + - "J108" + - "J11" + - "J110" + - "J111" + - "J118" + - "J12" + - "J120" + - "J121" + - "J122" + - "J123" + - "J128" + - "J129" + - "J13" + - "J14" + - "J15" + - "J150" + - "J151" + - "J152" + - "J153" + - "J154" + - "J155" + - "J156" + - "J157" + - "J158" + - "J159" + - "J16" + - "J160" + - "J168" + - "J17" + - "J170" + - "J171" + - "J172" + - "J173" + - "J178" + - "J18" + - "J180" + - "J181" + - "J182" + - "J188" + - "J189" + - name: "F00-F09 Organic, including symptomatic, mental disorders" + codings: + - "F00" + - "F000" + - "F001" + - "F002" + - "F009" + - "F01" + - "F010" + - "F011" + - "F012" + - "F013" + - "F018" + - "F019" + - "F02" + - "F020" + - "F021" + - "F022" + - "F023" + - "F024" + - "F028" + - "F03" + - "F04" + - "F05" + - "F050" + - "F051" + - "F058" + - "F059" + - "F06" + - "F060" + - "F061" + - "F062" + - "F063" + - "F064" + - "F065" + - "F066" + - "F067" + - "F068" + - "F069" + - "F07" + - "F070" + - "F071" + - "F072" + - "F078" + - "F079" + - "F09" + - name: "J84 Other interstitial pulmonary diseases" + codings: + - "J848" + - "J849" + - "J840" + - "J841" + - name: "G40 Epilepsy" + codings: + - "G400" + - "G401" + - "G402" + - "G403" + - "G404" + - "G405" + - "G406" + - "G407" + - "G408" + - "G409" + - name: "G43 Migraine" + codings: + - "G430" + - "G431" + - "G432" + - "G433" + - "G438" + - "G439" + - name: "G44 Other headache syndromes" + codings: + - "G444" + - "G448" + - "G440" + - "G441" + - "G442" + - "G443" + - name: "G45 Transient cerebral ischaemic attacks and related syndromes" + codings: + - "G450" + - "G451" + - "G452" + - "G453" + - "G454" + - "G458" + - "G459" + - name: "G47 Sleep disorders" + codings: + - "G470" + - "G471" + - "G472" + - "G473" + - "G474" + - "G478" + - "G479" + - name: "L40-L45 Papulosquamous disorders" + codings: + - "L40" + - "L400" + - "L401" + - "L402" + - "L403" + - "L404" + - "L405" + - "L408" + - "L409" + - "L41" + - "L410" + - "L411" + - "L412" + - "L413" + - "L414" + - "L415" + - "L418" + - "L419" + - "L42" + - "L43" + - "L430" + - "L431" + - "L432" + - "L433" + - "L438" + - "L439" + - "L44" + - "L440" + - "L441" + - "L442" + - "L443" + - "L444" + - "L448" + - "L449" + - "L45" + - name: "E53 Deficiency of other B group vitamins" + codings: + - "E531" + - "E538" + - "E539" + - "E530" + - name: "B34 Viral infection of unspecified site" + codings: + - "B340" + - "B341" + - "B342" + - "B343" + - "B344" + - "B348" + - "B349" + - name: "B37 Candidiasis" + codings: + - "B370" + - "B371" + - "B372" + - "B373" + - "B374" + - "B375" + - "B376" + - "B377" + - "B378" + - "B379" + - name: "O48 Prolonged pregnancy" + codings: + - "O48" + - name: "J35 Chronic diseases of tonsils and adenoids" + codings: + - "J353" + - "J358" + - "J359" + - "J350" + - "J351" + - "J352" + - name: "J30 Vasomotor and allergic rhinitis" + codings: + - "J300" + - "J301" + - "J302" + - "J303" + - "J304" + - name: "J31 Chronic rhinitis, nasopharyngitis and pharyngitis" + codings: + - "J312" + - "J310" + - "J311" + - name: "J32 Chronic sinusitis" + codings: + - "J320" + - "J321" + - "J322" + - "J323" + - "J324" + - "J328" + - "J329" + - name: "J33 Nasal polyp" + codings: + - "J330" + - "J331" + - "J338" + - "J339" + - name: "O42 Premature rupture of membranes" + codings: + - "O420" + - "O421" + - "O422" + - "O429" + - name: "J38 Diseases of vocal cords and larynx, not elsewhere classified" + codings: + - "J380" + - "J381" + - "J382" + - "J383" + - "J384" + - "J385" + - "J386" + - "J387" + - name: "J39 Other diseases of upper respiratory tract" + codings: + - "J390" + - "J391" + - "J392" + - "J393" + - "J398" + - "J399" + - name: "O46 Antepartum haemorrhage, not elsewhere classified" + codings: + - "O460" + - "O468" + - "O469" + - name: "O47 False labour" + codings: + - "O471" + - "O479" + - "O470" + - name: "G50-G59 Nerve, nerve root and plexus disorders" + codings: + - "G50" + - "G500" + - "G501" + - "G508" + - "G509" + - "G51" + - "G510" + - "G511" + - "G512" + - "G513" + - "G514" + - "G518" + - "G519" + - "G52" + - "G520" + - "G521" + - "G522" + - "G523" + - "G527" + - "G528" + - "G529" + - "G53" + - "G530" + - "G531" + - "G532" + - "G533" + - "G538" + - "G54" + - "G540" + - "G541" + - "G542" + - "G543" + - "G544" + - "G545" + - "G546" + - "G547" + - "G548" + - "G549" + - "G55" + - "G550" + - "G551" + - "G552" + - "G553" + - "G558" + - "G56" + - "G560" + - "G561" + - "G562" + - "G563" + - "G564" + - "G568" + - "G569" + - "G57" + - "G570" + - "G571" + - "G572" + - "G573" + - "G574" + - "G575" + - "G576" + - "G578" + - "G579" + - "G58" + - "G580" + - "G587" + - "G588" + - "G589" + - "G59" + - "G590" + - "G598" + - name: "I31 Other diseases of pericardium" + codings: + - "I310" + - "I311" + - "I312" + - "I313" + - "I318" + - "I319" + - name: "I35 Nonrheumatic aortic valve disorders" + codings: + - "I350" + - "I351" + - "I352" + - "I358" + - "I359" + - name: "I34 Nonrheumatic mitral valve disorders" + codings: + - "I340" + - "I341" + - "I342" + - "I348" + - "I349" + - name: "A41 Other septicaemia" + codings: + - "A418" + - "A419" + - "A410" + - "A411" + - "A412" + - "A413" + - "A414" + - "A415" + - name: "E15-E16 Other disorders of glucose regulation and pancreatic internal secretion" + codings: + - "E15" + - "E16" + - "E160" + - "E161" + - "E162" + - "E163" + - "E164" + - "E168" + - "E169" + - name: "F17 Mental and behavioural disorders due to use of tobacco" + codings: + - "F170" + - "F171" + - "F172" + - "F173" + - "F174" + - "F175" + - "F176" + - "F177" + - "F178" + - "F179" + - name: "A49 Bacterial infection of unspecified site" + codings: + - "A498" + - "A499" + - "A490" + - "A491" + - "A492" + - "A493" + - name: "N12 Tubulo-interstitial nephritis, not specified as acute or chronic" + codings: + - "N12" + - name: "N13 Obstructive and reflux uropathy" + codings: + - "N134" + - "N135" + - "N136" + - "N137" + - "N138" + - "N139" + - "N130" + - "N131" + - "N132" + - "N133" + - name: "N17 Acute renal failure" + codings: + - "N170" + - "N171" + - "N172" + - "N178" + - "N179" + - name: "G30-G32 Other degenerative diseases of the nervous system" + codings: + - "G30" + - "G300" + - "G301" + - "G308" + - "G309" + - "G31" + - "G310" + - "G311" + - "G312" + - "G318" + - "G319" + - "G32" + - "G320" + - "G328" + - name: "N18 Chronic renal failure" + codings: + - "N180" + - "N181" + - "N182" + - "N183" + - "N184" + - "N185" + - "N188" + - "N189" + - name: "N19 Unspecified renal failure" + codings: + - "N19" + - name: "K70 Alcoholic liver disease" + codings: + - "K700" + - "K701" + - "K702" + - "K703" + - "K704" + - "K709" + - name: "K75 Other inflammatory liver diseases" + codings: + - "K750" + - "K751" + - "K752" + - "K753" + - "K754" + - "K758" + - "K759" + - name: "K74 Fibrosis and cirrhosis of liver" + codings: + - "K744" + - "K745" + - "K746" + - "K740" + - "K741" + - "K742" + - "K743" + - name: "I49 Other cardiac arrhythmias" + codings: + - "I490" + - "I491" + - "I492" + - "I493" + - "I494" + - "I495" + - "I498" + - "I499" + - name: "I46 Cardiac arrest" + codings: + - "I461" + - "I469" + - "I460" + - name: "I47 Paroxysmal tachycardia" + codings: + - "I470" + - "I471" + - "I472" + - "I479" + - name: "I44 Atrioventricular and left bundle-branch block" + codings: + - "I440" + - "I441" + - "I442" + - "I443" + - "I444" + - "I445" + - "I446" + - "I447" + - name: "I45 Other conduction disorders" + codings: + - "I450" + - "I451" + - "I452" + - "I453" + - "I454" + - "I455" + - "I456" + - "I458" + - "I459" + - name: "I42 Cardiomyopathy" + codings: + - "I424" + - "I425" + - "I426" + - "I427" + - "I428" + - "I429" + - "I420" + - "I421" + - "I422" + - "I423" + - name: "M95-M99 Other disorders of the musculoskeletal system and connective tissue" + codings: + - "M95" + - "M950" + - "M951" + - "M952" + - "M953" + - "M954" + - "M955" + - "M958" + - "M959" + - "M9596" + - "M96" + - "M960" + - "M961" + - "M962" + - "M963" + - "M964" + - "M965" + - "M966" + - "M9663" + - "M9665" + - "M968" + - "M969" + - "M99" + - "M990" + - "M9900" + - "M9901" + - "M9902" + - "M9903" + - "M9904" + - "M9905" + - "M9906" + - "M9907" + - "M9908" + - "M9909" + - "M991" + - "M9910" + - "M9911" + - "M9912" + - "M9913" + - "M9914" + - "M9915" + - "M9916" + - "M9917" + - "M9918" + - "M9919" + - "M992" + - "M9920" + - "M9921" + - "M9922" + - "M9923" + - "M9924" + - "M9925" + - "M9926" + - "M9927" + - "M9928" + - "M9929" + - "M993" + - "M9930" + - "M9931" + - "M9932" + - "M9933" + - "M9934" + - "M9935" + - "M9936" + - "M9937" + - "M9938" + - "M9939" + - "M994" + - "M9940" + - "M9941" + - "M9942" + - "M9943" + - "M9944" + - "M9945" + - "M9946" + - "M9947" + - "M9948" + - "M9949" + - "M995" + - "M9950" + - "M9951" + - "M9952" + - "M9953" + - "M9954" + - "M9955" + - "M9956" + - "M9957" + - "M9958" + - "M9959" + - "M996" + - "M9960" + - "M9961" + - "M9962" + - "M9963" + - "M9964" + - "M9965" + - "M9966" + - "M9967" + - "M9968" + - "M9969" + - "M997" + - "M9970" + - "M9971" + - "M9972" + - "M9973" + - "M9974" + - "M9975" + - "M9976" + - "M9977" + - "M9978" + - "M9979" + - "M998" + - "M9980" + - "M9981" + - "M9982" + - "M9983" + - "M9984" + - "M9985" + - "M9986" + - "M9987" + - "M9988" + - "M9989" + - "M999" + - "M9990" + - "M9991" + - "M9992" + - "M9993" + - "M9994" + - "M9995" + - "M9996" + - "M9997" + - "M9998" + - "M9999" + - name: "H25 Senile cataract" + codings: + - "H259" + - "H250" + - "H251" + - "H252" + - "H258" + - name: "H26 Other cataract" + codings: + - "H260" + - "H261" + - "H262" + - "H263" + - "H264" + - "H268" + - "H269" + - name: "M65-M68 Disorders of synovium and tendon" + codings: + - "M6521" + - "M6522" + - "M6523" + - "M6524" + - "M6525" + - "M6526" + - "M6527" + - "M6528" + - "M6529" + - "M653" + - "M6530" + - "M6531" + - "M6532" + - "M6533" + - "M6534" + - "M6535" + - "M6536" + - "M6537" + - "M6538" + - "M6539" + - "M654" + - "M6540" + - "M6541" + - "M6542" + - "M6543" + - "M6544" + - "M6545" + - "M6546" + - "M6547" + - "M6548" + - "M6549" + - "M658" + - "M6580" + - "M6581" + - "M6582" + - "M6583" + - "M6584" + - "M6585" + - "M6586" + - "M6587" + - "M6588" + - "M6589" + - "M659" + - "M6590" + - "M6591" + - "M6592" + - "M6593" + - "M6594" + - "M6595" + - "M6596" + - "M6597" + - "M6598" + - "M6599" + - "M66" + - "M660" + - "M6600" + - "M6601" + - "M6602" + - "M6603" + - "M6604" + - "M6605" + - "M6606" + - "M6607" + - "M6608" + - "M6609" + - "M661" + - "M6610" + - "M6611" + - "M6612" + - "M6613" + - "M6614" + - "M6615" + - "M6616" + - "M6617" + - "M6618" + - "M6619" + - "M662" + - "M6620" + - "M6621" + - "M6622" + - "M6623" + - "M6624" + - "M6625" + - "M6626" + - "M6627" + - "M6628" + - "M6629" + - "M663" + - "M6630" + - "M6631" + - "M6632" + - "M6633" + - "M6634" + - "M6635" + - "M6636" + - "M6637" + - "M6638" + - "M6639" + - "M664" + - "M6640" + - "M6641" + - "M6642" + - "M6643" + - "M6644" + - "M6645" + - "M6646" + - "M6647" + - "M6648" + - "M6649" + - "M665" + - "M6650" + - "M6651" + - "M6652" + - "M6653" + - "M6654" + - "M6655" + - "M6656" + - "M6657" + - "M6658" + - "M6659" + - "M67" + - "M670" + - "M671" + - "M672" + - "M673" + - "M674" + - "M6743" + - "M6745" + - "M6747" + - "M6749" + - "M678" + - "M679" + - "M6796" + - "M68" + - "M680" + - "M688" + - "M65" + - "M650" + - "M6500" + - "M6501" + - "M6502" + - "M6503" + - "M6504" + - "M6505" + - "M6506" + - "M6507" + - "M6508" + - "M6509" + - "M651" + - "M6510" + - "M6511" + - "M6512" + - "M6513" + - "M6514" + - "M6515" + - "M6516" + - "M6517" + - "M6518" + - "M6519" + - "M652" + - "M6520" + - name: "O85-O92 Complications predominantly related to the puerperium" + codings: + - "O923" + - "O924" + - "O925" + - "O926" + - "O927" + - "O85" + - "O86" + - "O860" + - "O861" + - "O862" + - "O863" + - "O864" + - "O868" + - "O87" + - "O870" + - "O871" + - "O872" + - "O873" + - "O878" + - "O879" + - "O88" + - "O880" + - "O881" + - "O882" + - "O883" + - "O888" + - "O89" + - "O890" + - "O891" + - "O892" + - "O893" + - "O894" + - "O895" + - "O896" + - "O898" + - "O899" + - "O90" + - "O900" + - "O901" + - "O902" + - "O903" + - "O904" + - "O905" + - "O908" + - "O909" + - "O91" + - "O910" + - "O911" + - "O912" + - "O92" + - "O920" + - "O921" + - "O922" + - name: "N99 Postprocedural disorders of genito-urinary system, not elsewhere classified" + codings: + - "N990" + - "N991" + - "N992" + - "N993" + - "N994" + - "N995" + - "N998" + - "N999" + - name: "G35-G37 Demyelinating diseases of the central nervous system" + codings: + - "G375" + - "G378" + - "G379" + - "G35" + - "G36" + - "G360" + - "G361" + - "G368" + - "G369" + - "G37" + - "G370" + - "G371" + - "G372" + - "G373" + - "G374" + - name: "O00-O08 Pregnancy with abortive outcome" + codings: + - "O00" + - "O000" + - "O001" + - "O002" + - "O008" + - "O009" + - "O01" + - "O010" + - "O011" + - "O019" + - "O02" + - "O020" + - "O021" + - "O028" + - "O029" + - "O03" + - "O030" + - "O031" + - "O032" + - "O033" + - "O034" + - "O035" + - "O036" + - "O037" + - "O038" + - "O039" + - "O04" + - "O040" + - "O041" + - "O042" + - "O043" + - "O044" + - "O045" + - "O046" + - "O047" + - "O048" + - "O049" + - "O05" + - "O050" + - "O051" + - "O052" + - "O053" + - "O054" + - "O055" + - "O056" + - "O057" + - "O058" + - "O059" + - "O06" + - "O060" + - "O061" + - "O062" + - "O063" + - "O064" + - "O065" + - "O066" + - "O067" + - "O068" + - "O069" + - "O07" + - "O070" + - "O071" + - "O072" + - "O073" + - "O074" + - "O075" + - "O076" + - "O077" + - "O078" + - "O079" + - "O08" + - "O080" + - "O081" + - "O082" + - "O083" + - "O084" + - "O085" + - "O086" + - "O087" + - "O088" + - "O089" + - name: "I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified" + codings: + - "I80" + - "I800" + - "I801" + - "I802" + - "I803" + - "I808" + - "I809" + - "I81" + - "I82" + - "I820" + - "I821" + - "I822" + - "I823" + - "I828" + - "I829" + - "I83" + - "I830" + - "I831" + - "I832" + - "I839" + - "I84" + - "I840" + - "I841" + - "I842" + - "I843" + - "I844" + - "I845" + - "I846" + - "I847" + - "I848" + - "I849" + - "I85" + - "I850" + - "I859" + - "I86" + - "I860" + - "I861" + - "I862" + - "I863" + - "I864" + - "I868" + - "I87" + - "I870" + - "I871" + - "I872" + - "I878" + - "I879" + - "I88" + - "I880" + - "I881" + - "I888" + - "I889" + - "I89" + - "I890" + - "I891" + - "I898" + - "I899" + - name: "E00-E07 Disorders of thyroid gland" + codings: + - "E011" + - "E012" + - "E018" + - "E02" + - "E03" + - "E030" + - "E031" + - "E032" + - "E033" + - "E034" + - "E035" + - "E038" + - "E039" + - "E04" + - "E040" + - "E041" + - "E042" + - "E048" + - "E049" + - "E05" + - "E050" + - "E051" + - "E052" + - "E053" + - "E054" + - "E055" + - "E058" + - "E059" + - "E06" + - "E060" + - "E061" + - "E062" + - "E063" + - "E064" + - "E065" + - "E069" + - "E07" + - "E070" + - "E071" + - "E078" + - "E079" + - "E00" + - "E000" + - "E001" + - "E002" + - "E009" + - "E01" + - "E010" + - name: "M80-M85 Disorders of bone density and structure" + codings: + - "M80" + - "M800" + - "M8000" + - "M8001" + - "M8002" + - "M8003" + - "M8004" + - "M8005" + - "M8006" + - "M8007" + - "M8008" + - "M8009" + - "M801" + - "M8010" + - "M8011" + - "M8012" + - "M8013" + - "M8014" + - "M8015" + - "M8016" + - "M8017" + - "M8018" + - "M8019" + - "M802" + - "M8020" + - "M8021" + - "M8022" + - "M8023" + - "M8024" + - "M8025" + - "M8026" + - "M8027" + - "M8028" + - "M8029" + - "M803" + - "M8030" + - "M8031" + - "M8032" + - "M8033" + - "M8034" + - "M8035" + - "M8036" + - "M8037" + - "M8038" + - "M8039" + - "M804" + - "M8040" + - "M8041" + - "M8042" + - "M8043" + - "M8044" + - "M8045" + - "M8046" + - "M8047" + - "M8048" + - "M8049" + - "M805" + - "M8050" + - "M8051" + - "M8052" + - "M8053" + - "M8054" + - "M8055" + - "M8056" + - "M8057" + - "M8058" + - "M8059" + - "M808" + - "M8080" + - "M8081" + - "M8082" + - "M8083" + - "M8084" + - "M8085" + - "M8086" + - "M8087" + - "M8088" + - "M8089" + - "M809" + - "M8090" + - "M8091" + - "M8092" + - "M8093" + - "M8094" + - "M8095" + - "M8096" + - "M8097" + - "M8098" + - "M8099" + - "M81" + - "M810" + - "M8100" + - "M8101" + - "M8102" + - "M8103" + - "M8104" + - "M8105" + - "M8106" + - "M8107" + - "M8108" + - "M8109" + - "M811" + - "M8110" + - "M8111" + - "M8112" + - "M8113" + - "M8114" + - "M8115" + - "M8116" + - "M8117" + - "M8118" + - "M8119" + - "M812" + - "M8120" + - "M8121" + - "M8122" + - "M8123" + - "M8124" + - "M8125" + - "M8126" + - "M8127" + - "M8128" + - "M8129" + - "M813" + - "M8130" + - "M8131" + - "M8132" + - "M8133" + - "M8134" + - "M8135" + - "M8136" + - "M8137" + - "M8138" + - "M8139" + - "M814" + - "M8140" + - 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"M8287" + - "M8288" + - "M8289" + - "M83" + - "M830" + - "M8300" + - "M8301" + - "M8302" + - "M8303" + - "M8304" + - "M8305" + - "M8306" + - "M8307" + - "M8308" + - "M8309" + - "M831" + - "M8310" + - "M8311" + - "M8312" + - "M8313" + - "M8314" + - "M8315" + - "M8316" + - "M8317" + - "M8318" + - "M8319" + - "M832" + - "M8320" + - "M8321" + - "M8322" + - "M8323" + - "M8324" + - "M8325" + - "M8326" + - "M8327" + - "M8328" + - "M8329" + - "M833" + - "M8330" + - "M8331" + - "M8332" + - "M8333" + - "M8334" + - "M8335" + - "M8336" + - "M8337" + - "M8338" + - "M8339" + - "M834" + - "M8340" + - "M8341" + - "M8342" + - "M8343" + - "M8344" + - "M8345" + - "M8346" + - "M8347" + - "M8348" + - "M8349" + - "M835" + - "M8350" + - "M8351" + - "M8352" + - "M8353" + - "M8354" + - "M8355" + - "M8356" + - "M8357" + - "M8358" + - "M8359" + - "M838" + - "M8380" + - "M8381" + - "M8382" + - "M8383" + - "M8384" + - "M8385" + - "M8386" + - "M8387" + - "M8388" + - "M8389" + - "M839" + - "M8390" + - "M8391" + - "M8392" + - "M8393" + - "M8394" + - "M8395" + - "M8396" + - "M8397" + - "M8398" + - "M8399" + - "M84" + - "M840" + - "M8400" + - "M8401" + - "M8402" + - "M8403" + - "M8404" + - "M8405" + - "M8406" + - "M8407" + - "M8408" + - "M8409" + - "M841" + - "M8410" + - "M8411" + - "M8412" + - "M8413" + - "M8414" + - "M8415" + - "M8416" + - "M8417" + - "M8418" + - "M8419" + - "M842" + - "M8420" + - "M8421" + - "M8422" + - "M8423" + - "M8424" + - "M8425" + - "M8426" + - "M8427" + - "M8428" + - "M8429" + - "M843" + - "M8430" + - "M8431" + - "M8432" + - "M8433" + - "M8434" + - "M8435" + - "M8436" + - "M8437" + - "M8438" + - "M8439" + - "M844" + - "M8440" + - "M8441" + - "M8442" + - "M8443" + - "M8444" + - "M8445" + - "M8446" + - "M8447" + - "M8448" + - "M8449" + - "M848" + - "M8480" + - "M8481" + - "M8482" + - "M8483" + - "M8484" + - "M8485" + - "M8486" + - "M8487" + - "M8488" + - "M8489" + - "M849" + - "M8490" + - "M8491" + - "M8492" + - "M8493" + - "M8494" + - "M8495" + - "M8496" + - "M8497" + - "M8498" + - "M8499" + - "M85" + - "M850" + - "M8500" + - "M8501" + - "M8502" + - "M8503" + - "M8504" + - "M8505" + - "M8506" + - "M8507" + - "M8508" + - "M8509" + - "M851" + - "M8510" + - "M8511" + - "M8512" + - "M8513" + - "M8514" + - "M8515" + - "M8516" + - "M8517" + - "M8518" + - "M8519" + - "M852" + - "M8520" + - "M8521" + - "M8522" + - "M8523" + - "M8524" + - "M8525" + - "M8526" + - "M8527" + - "M8528" + - "M8529" + - "M853" + - "M8530" + - "M8531" + - "M8532" + - "M8533" + - "M8534" + - "M8535" + - "M8536" + - "M8537" + - "M8538" + - "M8539" + - "M854" + - "M8540" + - "M8541" + - "M8542" + - "M8543" + - "M8544" + - "M8545" + - "M8546" + - "M8547" + - "M8548" + - "M8549" + - "M855" + - "M8550" + - "M8551" + - "M8552" + - "M8553" + - "M8554" + - "M8555" + - "M8556" + - "M8557" + - "M8558" + - "M8559" + - "M856" + - "M8560" + - "M8561" + - "M8562" + - "M8563" + - "M8564" + - "M8565" + - "M8566" + - "M8567" + - "M8568" + - "M8569" + - "M858" + - "M8580" + - "M8581" + - "M8582" + - "M8583" + - "M8584" + - "M8585" + - "M8586" + - "M8587" + - "M8588" + - "M8589" + - "M859" + - "M8590" + - "M8591" + - "M8592" + - "M8593" + - "M8594" + - "M8595" + - "M8596" + - "M8597" + - "M8598" + - "M8599" + - name: "I10-I15 Hypertensive diseases" + codings: + - "I15" + - "I150" + - "I151" + - "I152" + - "I158" + - "I159" + - "I10" + - "I11" + - "I110" + - "I119" + - "I12" + - "I120" + - "I129" + - "I13" + - "I130" + - "I131" + - "I132" + - "I139" + - name: "J00-J06 Acute upper respiratory infections" + codings: + - "J00" + - "J01" + - "J010" + - "J011" + - "J012" + - "J013" + - "J014" + - "J018" + - "J019" + - "J02" + - "J020" + - "J028" + - "J029" + - "J03" + - "J030" + - "J038" + - "J039" + - "J04" + - "J040" + - "J041" + - "J042" + - "J05" + - "J050" + - "J051" + - "J06" + - "J060" + - "J068" + - "J069" + - name: "M10 Gout" + codings: + - "M100" + - "M1000" + - "M1001" + - "M1002" + - "M1003" + - "M1004" + - "M1005" + - "M1006" + - "M1007" + - "M1008" + - "M1009" + - "M101" + - "M1010" + - "M1011" + - "M1012" + - "M1013" + - "M1014" + - "M1015" + - "M1016" + - "M1017" + - "M1018" + - "M1019" + - "M102" + - "M1020" + - "M1021" + - "M1022" + - "M1023" + - "M1024" + - "M1025" + - "M1026" + - "M1027" + - "M1028" + - "M1029" + - "M103" + - "M1030" + - "M1031" + - "M1032" + - "M1033" + - "M1034" + - "M1035" + - "M1036" + - "M1037" + - "M1038" + - "M1039" + - "M104" + - "M1040" + - "M1041" + - "M1042" + - "M1043" + - "M1044" + - "M1045" + - "M1046" + - "M1047" + - "M1048" + - "M1049" + - "M109" + - "M1090" + - "M1091" + - "M1092" + - "M1093" + - "M1094" + - "M1095" + - "M1096" + - "M1097" + - "M1098" + - "M1099" + - name: "M13 Other arthritis" + codings: + - "M1394" + - "M1395" + - "M1396" + - "M1397" + - "M1398" + - "M1399" + - "M130" + - "M1300" + - "M1301" + - "M1302" + - "M1303" + - "M1304" + - "M1305" + - "M1306" + - "M1307" + - "M1308" + - "M1309" + - "M131" + - "M1310" + - "M1311" + - "M1312" + - "M1313" + - "M1314" + - "M1315" + - "M1316" + - "M1317" + - "M1318" + - "M1319" + - "M138" + - "M1380" + - "M1381" + - "M1382" + - "M1383" + - "M1384" + - "M1385" + - "M1386" + - "M1387" + - "M1388" + - "M1389" + - "M139" + - "M1390" + - "M1391" + - "M1392" + - "M1393" + - name: "M15 Polyarthrosis" + codings: + - "M150" + - "M1500" + - "M151" + - "M152" + - "M153" + - "M154" + - "M158" + - "M159" + - "M1599" + - name: "M17 Gonarthrosis [arthrosis of knee]" + codings: + - "M170" + - "M171" + - "M172" + - "M173" + - "M174" + - "M175" + - "M179" + - name: "M16 Coxarthrosis [arthrosis of hip]" + codings: + - "M166" + - "M167" + - "M169" + - "M160" + - "M161" + - "M162" + - "M163" + - "M164" + - "M165" + - name: "M19 Other arthrosis" + codings: + - "M190" + - "M1900" + - "M1901" + - "M1902" + - "M1903" + - "M1904" + - "M1905" + - "M1906" + - "M1907" + - "M1908" + - "M1909" + - "M191" + - "M1910" + - "M1911" + - "M1912" + - "M1913" + - "M1914" + - "M1915" + - "M1916" + - "M1917" + - "M1918" + - "M1919" + - "M192" + - "M1920" + - "M1921" + - "M1922" + - "M1923" + - "M1924" + - "M1925" + - "M1926" + - "M1927" + - "M1928" + - "M1929" + - "M198" + - "M1980" + - "M1981" + - "M1982" + - "M1983" + - "M1984" + - "M1985" + - "M1986" + - "M1987" + - "M1988" + - "M1989" + - "M199" + - "M1990" + - "M1991" + - "M1992" + - "M1993" + - "M1994" + - "M1995" + - "M1996" + - "M1997" + - "M1998" + - "M1999" + - name: "M18 Arthrosis of first carpometacarpal joint" + codings: + - "M180" + - "M181" + - "M182" + - "M183" + - "M184" + - "M185" + - "M189" + - name: "L53 Other erythematous conditions" + codings: + - "L530" + - "L531" + - "L532" + - "L533" + - "L538" + - "L539" + - name: "L57 Skin changes due to chronic exposure to nonionising radiation" + codings: + - "L570" + - "L571" + - "L572" + - "L573" + - "L574" + - "L575" + - "L578" + - "L579" + - name: "E11 Non-insulin-dependent diabetes mellitus" + codings: + - "E110" + - "E111" + - "E112" + - "E113" + - "E114" + - "E115" + - "E116" + - "E117" + - "E118" + - "E119" + - name: "E10 Insulin-dependent diabetes mellitus" + codings: + - "E100" + - "E101" + - "E102" + - "E103" + - "E104" + - "E105" + - "E106" + - "E107" + - "E108" + - "E109" + - name: "J47 Bronchiectasis" + codings: + - "J47" + - name: "E14 Unspecified diabetes mellitus" + codings: + - "E140" + - "E141" + - "E142" + - "E143" + - "E144" + - "E145" + - "E146" + - "E147" + - "E148" + - "E149" + - name: "J43 Emphysema" + codings: + - "J432" + - "J438" + - "J439" + - "J430" + - "J431" + - name: "E16 Other disorders of pancreatic internal secretion" + codings: + - "E160" + - "E161" + - "E162" + - "E163" + - "E164" + - "E168" + - "E169" + - name: "O04 Medical abortion" + codings: + - "O040" + - "O041" + - "O042" + - "O043" + - "O044" + - "O045" + - "O046" + - "O047" + - "O048" + - "O049" + - name: "O02 Other abnormal products of conception" + codings: + - "O020" + - "O021" + - "O028" + - "O029" + - name: "O03 Spontaneous abortion" + codings: + - "O031" + - "O032" + - "O033" + - "O034" + - "O035" + - "O036" + - "O037" + - "O038" + - "O039" + - "O030" + - name: "G95 Other diseases of spinal cord" + codings: + - "G950" + - "G951" + - "G952" + - "G958" + - "G959" + - name: "G93 Other disorders of brain" + codings: + - "G930" + - "G931" + - "G932" + - "G933" + - "G934" + - "G935" + - "G936" + - "G937" + - "G938" + - "G939" + - name: "G91 Hydrocephalus" + codings: + - "G910" + - "G911" + - "G912" + - "G913" + - "G918" + - "G919" + - name: "G99 Other disorders of nervous system in diseases classified elsewhere" + codings: + - "G990" + - "G991" + - "G992" + - "G998" + - name: "K29 Gastritis and duodenitis" + codings: + - "K290" + - "K291" + - "K292" + - "K293" + - "K294" + - "K295" + - "K296" + - "K297" + - "K298" + - "K299" + - name: "K22 Other diseases of oesophagus" + codings: + - "K220" + - "K221" + - "K222" + - "K223" + - "K224" + - "K225" + - "K226" + - "K227" + - "K228" + - "K229" + - name: "K20 Oesophagitis" + codings: + - "K20" + - name: "I26-I28 Pulmonary heart disease and diseases of pulmonary circulation" + codings: + - "I26" + - "I260" + - "I269" + - "I27" + - "I270" + - "I271" + - "I272" + - "I278" + - "I279" + - "I28" + - "I280" + - "I281" + - "I288" + - "I289" + - name: "K26 Duodenal ulcer" + codings: + - "K260" + - "K261" + - "K262" + - "K263" + - "K264" + - "K265" + - "K266" + - "K267" + - "K269" + - name: "K25 Gastric ulcer" + codings: + - "K259" + - "K250" + - "K251" + - "K252" + - "K253" + - "K254" + - "K255" + - "K256" + - "K257" + - name: "E86 Volume depletion" + codings: + - "E86" + - name: "E87 Other disorders of fluid, electrolyte and acid-base balance" + codings: + - "E876" + - "E877" + - "E878" + - "E870" + - "E871" + - "E872" + - "E873" + - "E874" + - "E875" + - name: "E83 Disorders of mineral metabolism" + codings: + - "E830" + - "E831" + - "E832" + - "E833" + - "E834" + - "E835" + - "E838" + - "E839" + - name: "E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified" + codings: + - "E890" + - "E891" + - "E892" + - "E893" + - "E894" + - "E895" + - "E896" + - "E898" + - "E899" + - name: "N50 Other disorders of male genital organs" + codings: + - "N500" + - "N501" + - "N508" + - "N509" + - name: "I60-I69 Cerebrovascular diseases" + codings: + - "I60" + - "I600" + - "I601" + - "I602" + - "I603" + - "I604" + - "I605" + - "I606" + - "I607" + - "I608" + - "I609" + - "I61" + - "I610" + - "I611" + - "I612" + - "I613" + - "I614" + - "I615" + - "I616" + - "I618" + - "I619" + - "I62" + - "I620" + - "I621" + - "I629" + - "I63" + - "I630" + - "I631" + - "I632" + - "I633" + - "I634" + - "I635" + - "I636" + - "I638" + - "I639" + - "I64" + - "I65" + - "I650" + - "I651" + - "I652" + - "I653" + - "I658" + - "I659" + - "I66" + - "I660" + - "I661" + - "I662" + - "I663" + - "I664" + - "I668" + - "I669" + - "I67" + - "I670" + - "I671" + - "I672" + - "I673" + - "I674" + - "I675" + - "I676" + - "I677" + - "I678" + - "I679" + - "I68" + - "I680" + - "I681" + - "I682" + - "I688" + - "I69" + - "I690" + - "I691" + - "I692" + - "I693" + - "I694" + - "I698" + - name: "M54 Dorsalgia" + codings: + - "M540" + - "M5400" + - "M5401" + - "M5402" + - "M5403" + - "M5404" + - "M5405" + - "M5406" + - "M5407" + - "M5408" + - "M5409" + - "M541" + - "M5410" + - "M5411" + - "M5412" + - "M5413" + - "M5414" + - "M5415" + - "M5416" + - "M5417" + - "M5418" + - "M5419" + - "M542" + - "M5420" + - "M5421" + - "M5422" + - "M5423" + - "M5424" + - "M5425" + - "M5426" + - "M5427" + - "M5428" + - "M5429" + - "M543" + - "M5430" + - "M5431" + - "M5432" + - "M5433" + - "M5434" + - "M5435" + - "M5436" + - "M5437" + - "M5438" + - "M5439" + - "M544" + - "M5440" + - "M5441" + - "M5442" + - "M5443" + - "M5444" + - "M5445" + - "M5446" + - "M5447" + - "M5448" + - "M5449" + - "M545" + - "M5450" + - "M5451" + - "M5452" + - "M5453" + - "M5454" + - "M5455" + - "M5456" + - "M5457" + - "M5458" + - "M5459" + - "M546" + - "M5460" + - "M5461" + - "M5462" + - "M5463" + - "M5464" + - "M5465" + - "M5466" + - "M5467" + - "M5468" + - "M5469" + - "M548" + - "M5480" + - "M5481" + - "M5482" + - "M5483" + - "M5484" + - "M5485" + - "M5486" + - "M5487" + - "M5488" + - "M5489" + - "M549" + - "M5490" + - "M5491" + - "M5492" + - "M5493" + - "M5494" + - "M5495" + - "M5496" + - "M5497" + - "M5498" + - "M5499" + - name: "B35-B49 Mycoses" + codings: + - "B35" + - "B350" + - "B351" + - "B352" + - "B353" + - "B354" + - "B355" + - "B356" + - "B358" + - "B359" + - "B36" + - "B360" + - "B361" + - "B362" + - "B363" + - "B368" + - "B369" + - "B37" + - "B370" + - "B371" + - "B372" + - "B373" + - "B374" + - "B375" + - "B376" + - "B377" + - "B378" + - "B379" + - "B38" + - "B380" + - "B381" + - "B382" + - "B383" + - "B384" + - "B387" + - "B388" + - "B389" + - "B39" + - "B390" + - "B391" + - "B392" + - "B393" + - "B394" + - "B395" + - "B399" + - "B40" + - "B400" + - "B401" + - "B402" + - "B403" + - "B407" + - "B408" + - "B409" + - "B41" + - "B410" + - "B417" + - "B418" + - "B419" + - "B42" + - "B420" + - "B421" + - "B427" + - "B428" + - "B429" + - "B43" + - "B430" + - "B431" + - "B432" + - "B438" + - "B439" + - "B44" + - "B440" + - "B441" + - "B442" + - "B447" + - "B448" + - "B449" + - "B45" + - "B450" + - "B451" + - "B452" + - "B453" + - "B457" + - "B458" + - "B459" + - "B46" + - "B460" + - "B461" + - "B462" + - "B463" + - "B464" + - "B465" + - "B468" + - "B469" + - "B47" + - "B470" + - "B471" + - "B479" + - "B48" + - "B480" + - "B481" + - "B482" + - "B483" + - "B484" + - "B487" + - "B488" + - "B49" + - name: "F20 Schizophrenia" + codings: + - "F200" + - "F201" + - "F202" + - "F203" + - "F204" + - "F205" + - "F206" + - "F208" + - "F209" + - name: "D50 Iron deficiency anaemia" + codings: + - "D501" + - "D508" + - "D509" + - "D500" + - name: "N99-N99 Other disorders of the genitourinary system" + codings: + - "N99" + - "N990" + - "N991" + - "N992" + - "N993" + - "N994" + - "N995" + - "N998" + - "N999" + - name: "N25-N29 Other disorders of kidney and ureter" + codings: + - "N279" + - "N28" + - "N280" + - "N281" + - "N288" + - "N289" + - "N29" + - "N290" + - "N291" + - "N298" + - "N25" + - "N250" + - "N251" + - "N258" + - "N259" + - "N26" + - "N27" + - "N270" + - "N271" + - name: "K70-K77 Diseases of liver" + codings: + - "K70" + - "K700" + - "K701" + - "K702" + - "K703" + - "K704" + - "K709" + - "K71" + - "K710" + - "K711" + - "K712" + - "K713" + - "K714" + - "K715" + - "K716" + - "K717" + - "K718" + - "K719" + - "K72" + - "K720" + - "K721" + - "K729" + - "K73" + - "K730" + - "K731" + - "K732" + - "K738" + - "K739" + - "K74" + - "K740" + - "K741" + - "K742" + - "K743" + - "K744" + - "K745" + - "K746" + - "K75" + - "K750" + - "K751" + - "K752" + - "K753" + - "K754" + - "K758" + - "K759" + - "K76" + - "K760" + - "K761" + - "K762" + - "K763" + - "K764" + - "K765" + - "K766" + - "K767" + - "K768" + - "K769" + - "K77" + - "K770" + - "K778" + - name: "I77 Other disorders of arteries and arterioles" + codings: + - "I770" + - "I771" + - "I772" + - "I773" + - "I774" + - "I775" + - "I776" + - "I778" + - "I779" + - name: "N28 Other disorders of kidney and ureter, not elsewhere classified" + codings: + - "N280" + - "N281" + - "N288" + - "N289" + - name: "I73 Other peripheral vascular diseases" + codings: + - "I730" + - "I731" + - "I738" + - "I739" + - name: "I05-I09 Chronic rheumatic heart diseases" + codings: + - "I05" + - "I050" + - "I051" + - "I052" + - "I058" + - "I059" + - "I06" + - "I060" + - "I061" + - "I062" + - "I068" + - "I069" + - "I07" + - "I070" + - "I071" + - "I072" + - "I078" + - "I079" + - "I08" + - "I080" + - "I081" + - "I082" + - "I083" + - "I088" + - "I089" + - "I09" + - "I090" + - "I091" + - "I092" + - "I098" + - "I099" + - name: "I71 Aortic aneurysm and dissection" + codings: + - "I710" + - "I711" + - "I712" + - "I713" + - "I714" + - "I715" + - "I716" + - "I718" + - "I719" + - name: "I70 Atherosclerosis" + codings: + - "I7081" + - "I709" + - "I7090" + - "I7091" + - "I700" + - "I7000" + - "I7001" + - "I701" + - "I7010" + - "I7011" + - "I702" + - "I7020" + - "I7021" + - "I708" + - "I7080" + - name: "N23 Unspecified renal colic" + codings: + - "N23" + - name: "N21 Calculus of lower urinary tract" + codings: + - "N211" + - "N218" + - "N219" + - "N210" + - name: "N20 Calculus of kidney and ureter" + codings: + - "N200" + - "N201" + - "N202" + - "N209" + - name: "I78 Diseases of capillaries" + codings: + - "I780" + - "I781" + - "I788" + - "I789" + - name: "E20-E35 Disorders of other endocrine glands" + codings: + - "E20" + - "E200" + - "E201" + - "E208" + - "E209" + - "E21" + - "E210" + - "E211" + - "E212" + - "E213" + - "E214" + - "E215" + - "E22" + - "E220" + - "E221" + - "E222" + - "E228" + - "E229" + - "E23" + - "E230" + - "E231" + - "E232" + - "E233" + - "E236" + - "E237" + - "E24" + - "E240" + - "E241" + - "E242" + - "E243" + - "E244" + - "E248" + - "E249" + - "E25" + - "E250" + - "E258" + - "E259" + - "E26" + - "E260" + - "E261" + - "E268" + - "E269" + - "E27" + - "E270" + - "E271" + - "E272" + - "E273" + - "E274" + - "E275" + - "E278" + - "E279" + - "E28" + - "E280" + - "E281" + - "E282" + - "E283" + - "E288" + - "E289" + - "E29" + - "E290" + - "E291" + - "E298" + - "E299" + - "E30" + - "E300" + - "E301" + - "E308" + - "E309" + - "E31" + - "E310" + - "E311" + - "E318" + - "E319" + - "E32" + - "E320" + - "E321" + - "E328" + - "E329" + - "E34" + - "E340" + - "E341" + - "E342" + - "E343" + - "E344" + - "E345" + - "E348" + - "E349" + - "E35" + - "E350" + - "E351" + - "E358" + - name: "M43 Other deforming dorsopathies" + codings: + - "M430" + - "M4300" + - "M4301" + - "M4302" + - "M4303" + - "M4304" + - "M4305" + - "M4306" + - "M4307" + - "M4308" + - "M4309" + - "M431" + - "M4310" + - "M4311" + - "M4312" + - "M4313" + - "M4314" + - "M4315" + - "M4316" + - "M4317" + - "M4318" + - "M4319" + - "M432" + - "M4320" + - "M4321" + - "M4322" + - "M4323" + - "M4324" + - "M4325" + - "M4326" + - "M4327" + - "M4328" + - "M4329" + - "M433" + - "M4330" + - "M4331" + - "M4332" + - "M4333" + - "M4334" + - "M4335" + - "M4336" + - "M4337" + - "M4338" + - "M4339" + - "M434" + - "M4340" + - "M4341" + - "M4342" + - "M4343" + - "M4344" + - "M4345" + - "M4346" + - "M4347" + - "M4348" + - "M4349" + - "M435" + - "M4350" + - "M4351" + - "M4352" + - "M4353" + - "M4354" + - "M4355" + - "M4356" + - "M4357" + - "M4358" + - "M4359" + - "M436" + - "M4360" + - "M4361" + - "M4362" + - "M4363" + - "M4364" + - "M4365" + - "M4366" + - "M4367" + - "M4368" + - "M4369" + - "M438" + - "M4380" + - "M4381" + - "M4382" + - "M4383" + - "M4384" + - "M4385" + - "M4386" + - "M4387" + - "M4388" + - "M4389" + - "M439" + - "M4390" + - "M4391" + - "M4392" + - "M4393" + - "M4394" + - "M4395" + - "M4396" + - "M4397" + - "M4398" + - "M4399" + - name: "M41 Scoliosis" + codings: + - "M410" + - "M4100" + - "M4101" + - "M4102" + - "M4103" + - "M4104" + - "M4105" + - "M4106" + - "M4107" + - "M4108" + - "M4109" + - "M411" + - "M4110" + - "M4111" + - "M4112" + - "M4113" + - "M4114" + - "M4115" + - "M4116" + - "M4117" + - "M4118" + - "M4119" + - "M412" + - "M4120" + - "M4121" + - "M4122" + - "M4123" + - "M4124" + - "M4125" + - "M4126" + - "M4127" + - "M4128" + - "M4129" + - "M413" + - "M4130" + - "M4131" + - "M4132" + - "M4133" + - "M4134" + - "M4135" + - "M4136" + - "M4137" + - "M4138" + - "M4139" + - "M414" + - "M4140" + - "M4141" + - "M4142" + - "M4143" + - "M4144" + - "M4145" + - "M4146" + - "M4147" + - "M4148" + - "M4149" + - "M415" + - "M4150" + - "M4151" + - "M4152" + - "M4153" + - "M4154" + - "M4155" + - "M4156" + - "M4157" + - "M4158" + - "M4159" + - "M418" + - "M4180" + - "M4181" + - "M4182" + - "M4183" + - "M4184" + - "M4185" + - "M4186" + - "M4187" + - "M4188" + - "M4189" + - "M419" + - "M4190" + - "M4191" + - "M4192" + - "M4193" + - "M4194" + - "M4195" + - "M4196" + - "M4197" + - "M4198" + - "M4199" + - name: "M46 Other inflammatory spondylopathies" + codings: + - "M460" + - "M4600" + - "M4601" + - "M4602" + - "M4603" + - "M4604" + - "M4605" + - "M4606" + - "M4607" + - "M4608" + - "M4609" + - "M461" + - "M4610" + - "M4611" + - "M4612" + - "M4613" + - "M4614" + - "M4615" + - "M4616" + - "M4617" + - "M4618" + - "M4619" + - "M462" + - "M4620" + - "M4621" + - "M4622" + - "M4623" + - "M4624" + - "M4625" + - "M4626" + - "M4627" + - "M4628" + - "M4629" + - "M463" + - "M4630" + - "M4631" + - "M4632" + - "M4633" + - "M4634" + - "M4635" + - "M4636" + - "M4637" + - "M4638" + - "M4639" + - "M464" + - "M4640" + - "M4641" + - "M4642" + - "M4643" + - "M4644" + - "M4645" + - "M4646" + - "M4647" + - "M4648" + - "M4649" + - "M465" + - "M4650" + - "M4651" + - "M4652" + - "M4653" + - "M4654" + - "M4655" + - "M4656" + - "M4657" + - "M4658" + - "M4659" + - "M468" + - "M4680" + - "M4681" + - "M4682" + - "M4683" + - "M4684" + - "M4685" + - "M4686" + - "M4687" + - "M4688" + - "M4689" + - "M469" + - "M4690" + - "M4691" + - "M4692" + - "M4693" + - "M4694" + - "M4695" + - "M4696" + - "M4697" + - "M4698" + - "M4699" + - name: "M47 Spondylosis" + codings: + - "M4729" + - "M478" + - "M4780" + - "M4781" + - "M4782" + - "M4783" + - "M4784" + - "M4785" + - "M4786" + - "M4787" + - "M4788" + - "M4789" + - "M479" + - "M4790" + - "M4791" + - "M4792" + - "M4793" + - "M4794" + - "M4795" + - "M4796" + - "M4797" + - "M4798" + - "M4799" + - "M470" + - "M4700" + - "M4701" + - "M4702" + - "M4703" + - "M4704" + - "M4705" + - "M4706" + - "M4707" + - "M4708" + - "M4709" + - "M471" + - "M4710" + - "M4711" + - "M4712" + - "M4713" + - "M4714" + - "M4715" + - "M4716" + - "M4717" + - "M4718" + - "M4719" + - "M472" + - "M4720" + - "M4721" + - "M4722" + - "M4723" + - "M4724" + - "M4725" + - "M4726" + - "M4727" + - "M4728" + - name: "K51 Ulcerative colitis" + codings: + - "K510" + - "K511" + - "K512" + - "K513" + - "K514" + - "K515" + - "K518" + - "K519" + - name: "N35 Urethral stricture" + codings: + - "N350" + - "N351" + - "N358" + - "N359" + - name: "F20-F29 Schizophrenia, schizotypal and delusional disorders" + codings: + - "F20" + - "F200" + - "F201" + - "F202" + - "F203" + - "F204" + - "F205" + - "F206" + - "F208" + - "F209" + - "F21" + - "F22" + - "F220" + - "F228" + - "F229" + - "F23" + - "F230" + - "F231" + - "F232" + - "F233" + - "F238" + - "F239" + - "F24" + - "F25" + - "F250" + - "F251" + - "F252" + - "F258" + - "F259" + - "F28" + - "F29" + - name: "H61 Other disorders of external ear" + codings: + - "H610" + - "H611" + - "H612" + - "H613" + - "H618" + - "H619" + - name: "H60 Otitis externa" + codings: + - "H600" + - "H601" + - "H602" + - "H603" + - "H604" + - "H605" + - "H608" + - "H609" + - name: "N40-N51 Diseases of male genital organs" + codings: + - "N40" + - "N41" + - "N410" + - "N411" + - "N412" + - "N413" + - "N418" + - "N419" + - "N42" + - "N420" + - "N421" + - "N422" + - "N423" + - "N428" + - "N429" + - "N43" + - "N430" + - "N431" + - "N432" + - "N433" + - "N434" + - "N44" + - "N45" + - "N450" + - "N459" + - "N46" + - "N47" + - "N48" + - "N480" + - "N481" + - "N482" + - "N483" + - "N484" + - "N485" + - "N486" + - "N488" + - "N489" + - "N49" + - "N490" + - "N491" + - "N492" + - "N498" + - "N499" + - "N50" + - "N500" + - "N501" + - "N508" + - "N509" + - "N51" + - "N510" + - "N511" + - "N512" + - "N518" + - name: "H65 Nonsuppurative otitis media" + codings: + - "H654" + - "H659" + - "H650" + - "H651" + - "H652" + - "H653" + - name: "H66 Suppurative and unspecified otitis media" + codings: + - "H660" + - "H661" + - "H662" + - "H663" + - "H664" + - "H669" + - name: "H83 Other diseases of inner ear" + codings: + - "H830" + - "H831" + - "H832" + - "H833" + - "H838" + - "H839" + - name: "H81 Disorders of vestibular function" + codings: + - "H810" + - "H811" + - "H812" + - "H813" + - "H814" + - "H818" + - "H819" + - name: "M86-M90 Other osteopathies" + codings: + - "M86" + - "M860" + - "M8600" + - "M8601" + - "M8602" + - "M8603" + - "M8604" + - "M8605" + - "M8606" + - "M8607" + - "M8608" + - "M8609" + - "M861" + - "M8610" + - "M8611" + - "M8612" + - "M8613" + - "M8614" + - "M8615" + - "M8616" + - "M8617" + - "M8618" + - "M8619" + - "M862" + - "M8620" + - "M8621" + - "M8622" + - "M8623" + - "M8624" + - "M8625" + - "M8626" + - "M8627" + - "M8628" + - "M8629" + - "M863" + - "M8630" + - "M8631" + - "M8632" + - "M8633" + - "M8634" + - "M8635" + - "M8636" + - "M8637" + - "M8638" + - "M8639" + - "M864" + - "M8640" + - "M8641" + - "M8642" + - "M8643" + - "M8644" + - "M8645" + - "M8646" + - "M8647" + - "M8648" + - "M8649" + - "M865" + - "M8650" + - "M8651" + - "M8652" + - "M8653" + - "M8654" + - "M8655" + - "M8656" + - "M8657" + - "M8658" + - "M8659" + - "M866" + - "M8660" + - "M8661" + - "M8662" + - "M8663" + - "M8664" + - "M8665" + - "M8666" + - "M8667" + - "M8668" + - "M8669" + - "M868" + - "M8680" + - "M8681" + - "M8682" + - "M8683" + - "M8684" + - "M8685" + - "M8686" + - "M8687" + - "M8688" + - "M8689" + - "M869" + - "M8690" + - "M8691" + - "M8692" + - "M8693" + - "M8694" + - "M8695" + - "M8696" + - "M8697" + - "M8698" + - "M8699" + - "M87" + - "M870" + - "M8700" + - "M8701" + - "M8702" + - "M8703" + - "M8704" + - "M8705" + - "M8706" + - "M8707" + - "M8708" + - "M8709" + - "M871" + - "M8710" + - "M8711" + - "M8712" + - "M8713" + - "M8714" + - "M8715" + - "M8716" + - "M8717" + - "M8718" + - "M8719" + - "M872" + - "M8720" + - "M8721" + - "M8722" + - "M8723" + - "M8724" + - "M8725" + - "M8726" + - "M8727" + - "M8728" + - "M8729" + - "M873" + - "M8730" + - "M8731" + - "M8732" + - "M8733" + - "M8734" + - "M8735" + - "M8736" + - "M8737" + - "M8738" + - "M8739" + - "M878" + - "M8780" + - "M8781" + - "M8782" + - "M8783" + - "M8784" + - "M8785" + - "M8786" + - "M8787" + - "M8788" + - "M8789" + - "M879" + - "M8790" + - "M8791" + - "M8792" + - "M8793" + - "M8794" + - "M8795" + - "M8796" + - "M8797" + - "M8798" + - "M8799" + - "M88" + - "M880" + - "M8800" + - "M8801" + - "M8802" + - "M8803" + - "M8804" + - "M8805" + - "M8806" + - "M8807" + - "M8808" + - "M8809" + - "M888" + - "M8880" + - "M8881" + - "M8882" + - "M8883" + - "M8884" + - "M8885" + - "M8886" + - "M8887" + - "M8888" + - "M8889" + - "M889" + - "M8890" + - "M8891" + - "M8892" + - "M8893" + - "M8894" + - "M8895" + - "M8896" + - "M8897" + - "M8898" + - "M8899" + - "M89" + - "M890" + - "M8900" + - "M8901" + - "M8902" + - "M8903" + - "M8904" + - "M8905" + - "M8906" + - "M8907" + - "M8908" + - "M8909" + - "M891" + - "M8910" + - "M8911" + - "M8912" + - "M8913" + - "M8914" + - "M8915" + - "M8916" + - "M8917" + - "M8918" + - "M8919" + - "M892" + - "M8920" + - "M8921" + - "M8922" + - "M8923" + - "M8924" + - "M8925" + - "M8926" + - "M8927" + - "M8928" + - "M8929" + - "M893" + - "M8930" + - "M8931" + - "M8932" + - "M8933" + - "M8934" + - "M8935" + - "M8936" + - "M8937" + - "M8938" + - "M8939" + - "M894" + - "M8940" + - "M8941" + - "M8942" + - "M8943" + - "M8944" + - "M8945" + - "M8946" + - "M8947" + - "M8948" + - "M8949" + - "M895" + - "M8950" + - "M8951" + - "M8952" + - "M8953" + - "M8954" + - "M8955" + - "M8956" + - "M8957" + - "M8958" + - "M8959" + - "M896" + - "M8960" + - "M8961" + - "M8962" + - "M8963" + - "M8964" + - "M8965" + - "M8966" + - "M8967" + - "M8968" + - "M8969" + - "M898" + - "M8980" + - "M8981" + - "M8982" + - "M8983" + - "M8984" + - "M8985" + - "M8986" + - "M8987" + - "M8988" + - "M8989" + - "M899" + - "M8990" + - "M8991" + - "M8992" + - "M8993" + - "M8994" + - "M8995" + - "M8996" + - "M8997" + - "M8998" + - "M8999" + - "M90" + - "M900" + - "M9000" + - "M9001" + - "M9002" + - "M9003" + - "M9004" + - "M9005" + - "M9006" + - "M9007" + - "M9008" + - "M9009" + - "M901" + - "M9010" + - "M9011" + - "M9012" + - "M9013" + - "M9014" + - "M9015" + - "M9016" + - "M9017" + - "M9018" + - "M9019" + - "M902" + - "M9020" + - "M9021" + - "M9022" + - "M9023" + - "M9024" + - "M9025" + - "M9026" + - "M9027" + - "M9028" + - "M9029" + - "M903" + - "M9030" + - "M9031" + - "M9032" + - "M9033" + - "M9034" + - "M9035" + - "M9036" + - "M9037" + - "M9038" + - "M9039" + - "M904" + - "M9040" + - "M9041" + - "M9042" + - "M9043" + - "M9044" + - "M9045" + - "M9046" + - "M9047" + - "M9048" + - "M9049" + - "M905" + - "M9050" + - "M9051" + - "M9052" + - "M9053" + - "M9054" + - "M9055" + - "M9056" + - "M9057" + - "M9058" + - "M9059" + - "M906" + - "M9060" + - "M9061" + - "M9062" + - "M9063" + - "M9064" + - "M9065" + - "M9066" + - "M9067" + - "M9068" + - "M9069" + - "M907" + - "M9070" + - "M9071" + - "M9072" + - "M9073" + - "M9074" + - "M9075" + - "M9076" + - "M9077" + - "M9078" + - "M9079" + - "M908" + - "M9080" + - "M9081" + - "M9082" + - "M9083" + - "M9084" + - "M9085" + - "M9086" + - "M9087" + - "M9088" + - "M9089" + - name: "N60-N64 Disorders of breast" + codings: + - "N640" + - "N641" + - "N642" + - "N643" + - "N644" + - "N645" + - "N648" + - "N649" + - "N60" + - "N600" + - "N601" + - "N602" + - "N603" + - "N604" + - "N608" + - "N609" + - "N61" + - "N62" + - "N63" + - "N64" + - name: "K40-K46 Hernia" + codings: + - "K40" + - "K400" + - "K401" + - "K402" + - "K403" + - "K404" + - "K409" + - "K41" + - "K410" + - "K411" + - "K412" + - "K413" + - "K414" + - "K419" + - "K42" + - "K420" + - "K421" + - "K429" + - "K43" + - "K430" + - "K431" + - "K432" + - "K433" + - "K434" + - "K435" + - "K436" + - "K437" + - "K439" + - "K44" + - "K440" + - "K441" + - "K449" + - "K45" + - "K450" + - "K451" + - "K458" + - "K46" + - "K460" + - "K461" + - "K469" + - name: "L85 Other epidermal thickening" + codings: + - "L850" + - "L851" + - "L852" + - "L853" + - "L858" + - "L859" + - name: "L82 Seborrhoeic keratosis" + codings: + - "L82" + - name: "L81 Other disorders of pigmentation" + codings: + - "L814" + - "L815" + - "L816" + - "L817" + - "L818" + - "L819" + - "L810" + - "L811" + - "L812" + - "L813" + - name: "L89 Decubitus ulcer" + codings: + - "L890" + - "L891" + - "L892" + - "L893" + - "L899" + - name: "M25 Other joint disorders, not elsewhere classified" + codings: + - "M250" + - "M2500" + - "M2501" + - "M2502" + - "M2503" + - "M2504" + - "M2505" + - "M2506" + - "M2507" + - "M2508" + - "M2509" + - "M251" + - "M2510" + - "M2511" + - "M2512" + - "M2513" + - "M2514" + - "M2515" + - "M2516" + - "M2517" + - "M2518" + - "M2519" + - "M252" + - "M2520" + - "M2521" + - "M2522" + - "M2523" + - "M2524" + - "M2525" + - "M2526" + - "M2527" + - "M2528" + - "M2529" + - "M253" + - "M2530" + - "M2531" + - "M2532" + - "M2533" + - "M2534" + - "M2535" + - "M2536" + - "M2537" + - "M2538" + - "M2539" + - "M254" + - "M2540" + - "M2541" + - "M2542" + - "M2543" + - "M2544" + - "M2545" + - "M2546" + - "M2547" + - "M2548" + - "M2549" + - "M255" + - "M2550" + - "M2551" + - "M2552" + - "M2553" + - "M2554" + - "M2555" + - "M2556" + - "M2557" + - "M2558" + - "M2559" + - "M256" + - "M2560" + - "M2561" + - "M2562" + - "M2563" + - "M2564" + - "M2565" + - "M2566" + - "M2567" + - "M2568" + - "M2569" + - "M257" + - "M2570" + - "M2571" + - "M2572" + - "M2573" + - "M2574" + - "M2575" + - "M2576" + - "M2577" + - "M2578" + - "M2579" + - "M258" + - "M2580" + - "M2581" + - "M2582" + - "M2583" + - "M2584" + - "M2585" + - "M2586" + - "M2587" + - "M2588" + - "M2589" + - "M259" + - "M2590" + - "M2591" + - "M2592" + - "M2593" + - "M2594" + - "M2595" + - "M2596" + - "M2597" + - "M2598" + - "M2599" + - name: "J96 Respiratory failure, not elsewhere classified" + codings: + - "J960" + - "J9600" + - "J9601" + - "J9609" + - "J961" + - "J9610" + - "J9611" + - "J9619" + - "J969" + - "J9690" + - "J9691" + - "J9699" + - name: "J92 Pleural plaque" + codings: + - "J920" + - "J929" + - name: "J93 Pneumothorax" + codings: + - "J930" + - "J931" + - "J938" + - "J939" + - name: "J90 Pleural effusion, not elsewhere classified" + codings: + - "J90" + - name: "J98 Other respiratory disorders" + codings: + - "J988" + - "J989" + - "J980" + - "J981" + - "J982" + - "J983" + - "J984" + - "J985" + - "J986" + - name: "D60-D64 Aplastic and other anaemias" + codings: + - "D630" + - "D631" + - "D638" + - "D64" + - "D640" + - "D641" + - "D642" + - "D643" + - "D644" + - "D648" + - "D649" + - "D60" + - "D600" + - "D601" + - "D608" + - "D609" + - "D61" + - "D610" + - "D611" + - "D612" + - "D613" + - "D618" + - "D619" + - "D62" + - "D63" + - name: "B07 Viral warts" + codings: + - "B07" + - name: "E65-E68 Obesity and other hyperalimentation" + codings: + - "E65" + - "E66" + - "E660" + - "E661" + - "E662" + - "E668" + - "E669" + - "E67" + - "E670" + - "E671" + - "E672" + - "E673" + - "E678" + - "E68" + - name: "J40 Bronchitis, not specified as acute or chronic" + codings: + - "J40" + - name: "O75 Other complications of labour and delivery, not elsewhere classified" + codings: + - "O750" + - "O751" + - "O752" + - "O753" + - "O754" + - "O755" + - "O756" + - "O757" + - "O758" + - "O759" + - name: "J03 Acute tonsillitis" + codings: + - "J030" + - "J038" + - "J039" + - name: "J02 Acute pharyngitis" + codings: + - "J020" + - "J028" + - "J029" + - name: "O70 Perineal laceration during delivery" + codings: + - "O700" + - "O701" + - "O702" + - "O703" + - "O709" + - name: "O72 Postpartum haemorrhage" + codings: + - "O720" + - "O721" + - "O722" + - "O723" + - name: "K13 Other diseases of lip and oral mucosa" + codings: + - "K130" + - "K131" + - "K132" + - "K1329" + - "K133" + - "K134" + - "K135" + - "K136" + - "K137" + - name: "K12 Stomatitis and related lesions" + codings: + - "K120" + - "K121" + - "K122" + - "K123" + - name: "K11 Diseases of salivary glands" + codings: + - "K110" + - "K111" + - "K112" + - "K113" + - "K114" + - "K115" + - "K116" + - "K117" + - "K118" + - "K119" + - name: "K14 Diseases of tongue" + codings: + - "K145" + - "K146" + - "K148" + - "K149" + - "K140" + - "K141" + - "K142" + - "K143" + - "K144" + - name: "I20 Angina pectoris" + codings: + - "I201" + - "I208" + - "I209" + - "I200" + - name: "I21 Acute myocardial infarction" + codings: + - "I210" + - "I211" + - "I212" + - "I213" + - "I214" + - "I219" + - "I21X" + - name: "I22 Subsequent myocardial infarction" + codings: + - "I220" + - "I221" + - "I228" + - "I229" + - name: "I24 Other acute ischaemic heart diseases" + codings: + - "I240" + - "I241" + - "I248" + - "I249" + - name: "I25 Chronic ischaemic heart disease" + codings: + - "I250" + - "I251" + - "I252" + - "I253" + - "I254" + - "I255" + - "I256" + - "I258" + - "I259" + - name: "I26 Pulmonary embolism" + codings: + - "I260" + - "I269" + - name: "I27 Other pulmonary heart diseases" + codings: + - "I279" + - "I270" + - "I271" + - "I272" + - "I278" + - name: "M40-M43 Deforming dorsopathies" + codings: + - "M4034" + - "M4035" + - "M4036" + - "M4037" + - "M4038" + - "M4039" + - "M404" + - "M4040" + - "M4041" + - "M4042" + - "M4043" + - "M4044" + - "M4045" + - "M4046" + - "M4047" + - "M4048" + - "M4049" + - "M405" + - "M4050" + - "M4051" + - "M4052" + - "M4053" + - "M4054" + - "M4055" + - "M4056" + - "M4057" + - "M4058" + - "M4059" + - "M41" + - "M410" + - "M4100" + - "M4101" + - "M4102" + - "M4103" + - "M4104" + - "M4105" + - "M4106" + - "M4107" + - "M4108" + - "M4109" + - "M411" + - "M4110" + - "M4111" + - "M4112" + - "M4113" + - "M4114" + - "M4115" + - "M4116" + - "M4117" + - "M4118" + - "M4119" + - "M412" + - "M4120" + - "M4121" + - "M4122" + - "M4123" + - "M4124" + - "M4125" + - "M4126" + - "M4127" + - "M4128" + - "M4129" + - "M413" + - "M4130" + - "M4131" + - "M4132" + - "M4133" + - "M4134" + - "M4135" + - "M4136" + - "M4137" + - "M4138" + - "M4139" + - "M414" + - "M4140" + - "M4141" + - "M4142" + - "M4143" + - "M4144" + - "M4145" + - "M4146" + - "M4147" + - "M4148" + - "M4149" + - "M415" + - "M4150" + - "M4151" + - "M4152" + - "M4153" + - "M4154" + - "M4155" + - "M4156" + - "M4157" + - "M4158" + - "M4159" + - "M418" + - "M4180" + - "M4181" + - "M4182" + - "M4183" + - "M4184" + - "M4185" + - "M4186" + - "M4187" + - "M4188" + - "M4189" + - "M419" + - "M4190" + - "M4191" + - "M4192" + - "M4193" + - "M4194" + - "M4195" + - "M4196" + - "M4197" + - "M4198" + - "M4199" + - "M42" + - "M420" + - "M4200" + - "M4201" + - "M4202" + - "M4203" + - "M4204" + - "M4205" + - "M4206" + - "M4207" + - "M4208" + - "M4209" + - "M421" + - "M4210" + - "M4211" + - "M4212" + - "M4213" + - "M4214" + - "M4215" + - "M4216" + - "M4217" + - "M4218" + - "M4219" + - "M429" + - "M4290" + - "M4291" + - "M4292" + - "M4293" + - "M4294" + - "M4295" + - "M4296" + - "M4297" + - "M4298" + - "M4299" + - "M43" + - "M430" + - "M4300" + - "M4301" + - "M4302" + - "M4303" + - "M4304" + - "M4305" + - "M4306" + - "M4307" + - "M4308" + - "M4309" + - "M431" + - "M4310" + - "M4311" + - "M4312" + - "M4313" + - "M4314" + - "M4315" + - "M4316" + - "M4317" + - "M4318" + - "M4319" + - "M432" + - "M4320" + - "M4321" + - "M4322" + - "M4323" + - "M4324" + - "M4325" + - "M4326" + - "M4327" + - "M4328" + - "M4329" + - "M433" + - "M4330" + - "M4331" + - "M4332" + - "M4333" + - "M4334" + - "M4335" + - "M4336" + - "M4337" + - "M4338" + - "M4339" + - "M434" + - "M4340" + - "M4341" + - "M4342" + - "M4343" + - "M4344" + - "M4345" + - "M4346" + - "M4347" + - "M4348" + - "M4349" + - "M435" + - "M4350" + - "M4351" + - "M4352" + - "M4353" + - "M4354" + - "M4355" + - "M4356" + - "M4357" + - "M4358" + - "M4359" + - "M436" + - "M4360" + - "M4361" + - "M4362" + - "M4363" + - "M4364" + - "M4365" + - "M4366" + - "M4367" + - "M4368" + - "M4369" + - "M438" + - "M4380" + - "M4381" + - "M4382" + - "M4383" + - "M4384" + - "M4385" + - "M4386" + - "M4387" + - "M4388" + - "M4389" + - "M439" + - "M4390" + - "M4391" + - "M4392" + - "M4393" + - "M4394" + - "M4395" + - "M4396" + - "M4397" + - "M4398" + - "M4399" + - "M40" + - "M400" + - "M4000" + - "M4001" + - "M4002" + - "M4003" + - "M4004" + - "M4005" + - "M4006" + - "M4007" + - "M4008" + - "M4009" + - "M401" + - "M4010" + - "M4011" + - "M4012" + - "M4013" + - "M4014" + - "M4015" + - "M4016" + - "M4017" + - "M4018" + - "M4019" + - "M402" + - "M4020" + - "M4021" + - "M4022" + - "M4023" + - "M4024" + - "M4025" + - "M4026" + - "M4027" + - "M4028" + - "M4029" + - "M403" + - "M4030" + - "M4031" + - "M4032" + - "M4033" + - name: "J30-J39 Other diseases of upper respiratory tract" + codings: + - "J353" + - "J358" + - "J359" + - "J36" + - "J37" + - "J370" + - "J371" + - "J38" + - "J380" + - "J381" + - "J382" + - "J383" + - "J384" + - "J385" + - "J386" + - "J387" + - "J39" + - "J390" + - "J391" + - "J392" + - "J393" + - "J398" + - "J399" + - "J30" + - "J300" + - "J301" + - "J302" + - "J303" + - "J304" + - "J31" + - "J310" + - "J311" + - "J312" + - "J32" + - "J320" + - "J321" + - "J322" + - "J323" + - "J324" + - "J328" + - "J329" + - "J33" + - "J330" + - "J331" + - "J338" + - "J339" + - "J34" + - "J340" + - "J341" + - "J342" + - "J343" + - "J348" + - "J35" + - "J350" + - "J351" + - "J352" + - name: "N64 Other disorders of breast" + codings: + - "N640" + - "N641" + - "N642" + - "N643" + - "N644" + - "N645" + - "N648" + - "N649" + - name: "N63 Unspecified lump in breast" + codings: + - "N63" + - name: "N62 Hypertrophy of breast" + codings: + - "N62" + - name: "N60 Benign mammary dysplasia" + codings: + - "N600" + - "N601" + - "N602" + - "N603" + - "N604" + - "N608" + - "N609" + - name: "K66 Other disorders of peritoneum" + codings: + - "K669" + - "K660" + - "K661" + - "K668" + - name: "J45 Asthma" + codings: + - "J450" + - "J451" + - "J458" + - "J459" + - name: "K62 Other diseases of anus and rectum" + codings: + - "K620" + - "K621" + - "K622" + - "K623" + - "K624" + - "K625" + - "K626" + - "K627" + - "K628" + - "K629" + - name: "K63 Other diseases of intestine" + codings: + - "K631" + - "K632" + - "K633" + - "K634" + - "K635" + - "K638" + - "K639" + - "K630" + - name: "K60 Fissure and fistula of anal and rectal regions" + codings: + - "K600" + - "K601" + - "K602" + - "K603" + - "K604" + - "K605" + - name: "J44 Other chronic obstructive pulmonary disease" + codings: + - "J440" + - "J441" + - "J448" + - "J449" + - name: "L60-L75 Disorders of skin appendages" + codings: + - "L60" + - "L600" + - "L601" + - "L602" + - "L603" + - "L604" + - "L605" + - "L608" + - "L609" + - "L62" + - "L620" + - "L628" + - "L63" + - "L630" + - "L631" + - "L632" + - "L638" + - "L639" + - "L64" + - "L640" + - "L648" + - "L649" + - "L65" + - "L650" + - "L651" + - "L652" + - "L658" + - "L659" + - "L66" + - "L660" + - "L661" + - "L662" + - "L663" + - "L664" + - "L668" + - "L669" + - "L67" + - "L670" + - "L671" + - "L678" + - "L679" + - "L68" + - "L680" + - "L681" + - "L682" + - "L683" + - "L688" + - "L689" + - "L70" + - "L700" + - "L701" + - "L702" + - "L703" + - "L704" + - "L705" + - "L708" + - "L709" + - "L71" + - "L710" + - "L711" + - "L718" + - "L719" + - "L72" + - "L720" + - "L721" + - "L722" + - "L728" + - "L729" + - "L73" + - "L730" + - "L731" + - "L732" + - "L738" + - "L739" + - "L74" + - "L740" + - "L741" + - "L742" + - "L743" + - "L744" + - "L748" + - "L749" + - "L75" + - "L750" + - "L751" + - "L752" + - "L758" + - "L759" + - name: "I95 Hypotension" + codings: + - "I959" + - "I950" + - "I951" + - "I952" + - "I958" + - name: "E10-E14 Diabetes mellitus" + codings: + - "E10" + - "E100" + - "E101" + - "E102" + - "E103" + - "E104" + - "E105" + - "E106" + - "E107" + - "E108" + - "E109" + - "E11" + - "E110" + - "E111" + - "E112" + - "E113" + - "E114" + - "E115" + - "E116" + - "E117" + - "E118" + - "E119" + - "E12" + - "E120" + - "E121" + - "E122" + - "E123" + - "E124" + - "E125" + - "E126" + - "E127" + - "E128" + - "E129" + - "E13" + - "E130" + - "E131" + - "E132" + - "E133" + - "E134" + - "E135" + - "E136" + - "E137" + - "E138" + - "E139" + - "E14" + - "E140" + - "E141" + - "E142" + - "E143" + - "E144" + - "E145" + - "E146" + - "E147" + - "E148" + - "E149" + - name: "M94 Other disorders of cartilage" + codings: + - "M9417" + - "M9418" + - "M9419" + - "M942" + - "M9420" + - "M9421" + - "M9422" + - "M9423" + - "M9424" + - "M9425" + - "M9426" + - "M9427" + - "M9428" + - "M9429" + - "M943" + - "M9430" + - "M9431" + - "M9432" + - "M9433" + - "M9434" + - "M9435" + - "M9436" + - "M9437" + - "M9438" + - "M9439" + - "M948" + - "M9480" + - "M9481" + - "M9482" + - "M9483" + - "M9484" + - "M9485" + - "M9486" + - "M9487" + - "M9488" + - "M9489" + - "M949" + - "M9490" + - "M9491" + - "M9492" + - "M9493" + - "M9494" + - "M9495" + - "M9496" + - "M9497" + - "M9498" + - "M9499" + - "M940" + - "M9400" + - "M9401" + - "M9402" + - "M9403" + - "M9404" + - "M9405" + - "M9406" + - "M9407" + - "M9408" + - "M9409" + - "M941" + - "M9410" + - "M9411" + - "M9412" + - "M9413" + - "M9414" + - "M9415" + - "M9416" + - name: "F30-F39 Mood [affective] disorders" + codings: + - "F30" + - "F300" + - "F301" + - "F302" + - "F308" + - "F309" + - "F31" + - "F310" + - "F311" + - "F312" + - "F313" + - "F314" + - "F315" + - "F316" + - "F317" + - "F318" + - "F319" + - "F32" + - "F320" + - "F321" + - "F322" + - "F323" + - "F328" + - "F329" + - "F33" + - "F330" + - "F331" + - "F332" + - "F333" + - "F334" + - "F338" + - "F339" + - "F34" + - "F340" + - "F341" + - "F348" + - "F349" + - "F38" + - "F380" + - "F381" + - "F388" + - "F39" + - name: "M15-M19 Arthrosis" + codings: + - "M15" + - "M150" + - "M1500" + - "M151" + - "M152" + - "M153" + - "M154" + - "M158" + - "M159" + - "M1599" + - "M16" + - "M160" + - "M161" + - "M162" + - "M163" + - "M164" + - "M165" + - "M166" + - "M167" + - "M169" + - "M17" + - "M170" + - "M171" + - "M172" + - "M173" + - "M174" + - "M175" + - "M179" + - "M18" + - "M180" + - "M181" + - "M182" + - "M183" + - "M184" + - "M185" + - "M189" + - "M19" + - "M190" + - "M1900" + - "M1901" + - "M1902" + - "M1903" + - "M1904" + - "M1905" + - "M1906" + - "M1907" + - "M1908" + - "M1909" + - "M191" + - "M1910" + - "M1911" + - "M1912" + - "M1913" + - "M1914" + - "M1915" + - "M1916" + - "M1917" + - "M1918" + - "M1919" + - "M192" + - "M1920" + - "M1921" + - "M1922" + - "M1923" + - "M1924" + - "M1925" + - "M1926" + - "M1927" + - "M1928" + - "M1929" + - "M198" + - "M1980" + - "M1981" + - "M1982" + - "M1983" + - "M1984" + - "M1985" + - "M1986" + - "M1987" + - "M1988" + - "M1989" + - "M199" + - "M1990" + - "M1991" + - "M1992" + - "M1993" + - "M1994" + - "M1995" + - "M1996" + - "M1997" + - "M1998" + - "M1999" + - name: "H10-H13 Disorders of conjunctiva" + codings: + - "H10" + - "H100" + - "H101" + - "H102" + - "H103" + - "H104" + - "H105" + - "H108" + - "H109" + - "H11" + - "H110" + - "H111" + - "H112" + - "H113" + - "H114" + - "H118" + - "H119" + - "H13" + - "H130" + - "H131" + - "H132" + - "H133" + - "H138" + - name: "M72 Fibroblastic disorders" + codings: + - "M720" + - "M7200" + - "M7201" + - "M7202" + - "M7203" + - "M7204" + - "M7205" + - "M7206" + - "M7207" + - "M7208" + - "M7209" + - "M721" + - "M7210" + - "M7211" + - "M7212" + - "M7213" + - "M7214" + - "M7215" + - "M7216" + - "M7217" + - "M7218" + - "M7219" + - "M722" + - "M7220" + - "M7221" + - "M7222" + - "M7223" + - "M7224" + - "M7225" + - "M7226" + - "M7227" + - "M7228" + - "M7229" + - "M723" + - "M7230" + - "M7231" + - "M7232" + - "M7233" + - "M7234" + - "M7235" + - "M7236" + - "M7237" + - "M7238" + - "M7239" + - "M724" + - "M7240" + - "M7241" + - "M7242" + - "M7243" + - "M7244" + - "M7245" + - "M7246" + - "M7247" + - "M7248" + - "M7249" + - "M725" + - "M7250" + - "M7251" + - "M7252" + - "M7253" + - "M7254" + - "M7255" + - "M7256" + - "M7257" + - "M7258" + - "M7259" + - "M726" + - "M7260" + - "M7261" + - "M7262" + - "M7263" + - "M7264" + - "M7265" + - "M7266" + - "M7267" + - "M7268" + - "M7269" + - "M728" + - "M7280" + - "M7281" + - "M7282" + - "M7283" + - "M7284" + - "M7285" + - "M7286" + - "M7287" + - "M7288" + - "M7289" + - "M729" + - "M7290" + - "M7291" + - "M7292" + - "M7293" + - "M7294" + - "M7295" + - "M7296" + - "M7297" + - "M7298" + - "M7299" + - name: "M71 Other bursopathies" + codings: + - "M710" + - "M7100" + - "M7101" + - "M7102" + - "M7103" + - "M7104" + - "M7105" + - "M7106" + - "M7107" + - "M7108" + - "M7109" + - "M711" + - "M7110" + - "M7111" + - "M7112" + - "M7113" + - "M7114" + - "M7115" + - "M7116" + - "M7117" + - "M7118" + - "M7119" + - "M712" + - "M7120" + - "M7121" + - "M7122" + - "M7123" + - "M7124" + - "M7125" + - "M7126" + - "M7127" + - "M7128" + - "M7129" + - "M713" + - "M7130" + - "M7131" + - "M7132" + - "M7133" + - "M7134" + - "M7135" + - "M7136" + - "M7137" + - "M7138" + - "M7139" + - "M714" + - "M7140" + - "M7141" + - "M7142" + - "M7143" + - "M7144" + - "M7145" + - "M7146" + - "M7147" + - "M7148" + - "M7149" + - "M715" + - "M7150" + - "M7151" + - "M7152" + - "M7153" + - "M7154" + - "M7155" + - "M7156" + - "M7157" + - "M7158" + - "M7159" + - "M718" + - "M7180" + - "M7181" + - "M7182" + - "M7183" + - "M7184" + - "M7185" + - "M7186" + - "M7187" + - "M7188" + - "M7189" + - "M719" + - "M7190" + - "M7191" + - "M7192" + - "M7193" + - "M7194" + - "M7195" + - "M7196" + - "M7197" + - "M7198" + - "M7199" + - name: "M70 Soft tissue disorders related to use, overuse and pressure" + codings: + - "M700" + - "M7000" + - "M7001" + - "M7002" + - "M7003" + - "M7004" + - "M7005" + - "M7006" + - "M7007" + - "M7008" + - "M7009" + - "M701" + - "M7010" + - "M7011" + - "M7012" + - "M7013" + - "M7014" + - "M7015" + - "M7016" + - "M7017" + - "M7018" + - "M7019" + - "M702" + - "M7020" + - "M7021" + - "M7022" + - "M7023" + - "M7024" + - "M7025" + - "M7026" + - "M7027" + - "M7028" + - "M7029" + - "M703" + - "M7030" + - "M7031" + - "M7032" + - "M7033" + - "M7034" + - "M7035" + - "M7036" + - "M7037" + - "M7038" + - "M7039" + - "M704" + - "M7040" + - "M7041" + - "M7042" + - "M7043" + - "M7044" + - "M7045" + - "M7046" + - "M7047" + - "M7048" + - "M7049" + - "M705" + - "M7050" + - "M7051" + - "M7052" + - "M7053" + - "M7054" + - "M7055" + - "M7056" + - "M7057" + - "M7058" + - "M7059" + - "M706" + - "M7060" + - "M7061" + - "M7062" + - "M7063" + - "M7064" + - "M7065" + - "M7066" + - "M7067" + - "M7068" + - "M7069" + - "M707" + - "M7070" + - "M7071" + - "M7072" + - "M7073" + - "M7074" + - "M7075" + - "M7076" + - "M7077" + - "M7078" + - "M7079" + - "M708" + - "M7080" + - "M7081" + - "M7082" + - "M7083" + - "M7084" + - "M7085" + - "M7086" + - "M7087" + - "M7088" + - "M7089" + - "M709" + - "M7090" + - "M7091" + - "M7092" + - "M7093" + - "M7094" + - "M7095" + - "M7096" + - "M7097" + - "M7098" + - "M7099" + - name: "M77 Other enthesopathies" + codings: + - "M770" + - "M7700" + - "M7701" + - "M7702" + - "M7703" + - "M7704" + - "M7705" + - "M7706" + - "M7707" + - "M7708" + - "M7709" + - "M771" + - "M7710" + - "M7711" + - "M7712" + - "M7713" + - "M7714" + - "M7715" + - "M7716" + - "M7717" + - "M7718" + - "M7719" + - "M772" + - "M7720" + - "M7721" + - "M7722" + - "M7723" + - "M7724" + - "M7725" + - "M7726" + - "M7727" + - "M7728" + - "M7729" + - "M773" + - "M7730" + - "M7731" + - "M7732" + - "M7733" + - "M7734" + - "M7735" + - "M7736" + - "M7737" + - "M7738" + - "M7739" + - "M774" + - "M7740" + - "M7741" + - "M7742" + - "M7743" + - "M7744" + - "M7745" + - "M7746" + - "M7747" + - "M7748" + - "M7749" + - "M775" + - "M7750" + - "M7751" + - "M7752" + - "M7753" + - "M7754" + - "M7755" + - "M7756" + - "M7757" + - "M7758" + - "M7759" + - "M778" + - "M7780" + - "M7781" + - "M7782" + - "M7783" + - "M7784" + - "M7785" + - "M7786" + - "M7787" + - "M7788" + - "M7789" + - "M779" + - "M7790" + - "M7791" + - "M7792" + - "M7793" + - "M7794" + - "M7795" + - "M7796" + - "M7797" + - "M7798" + - "M7799" + - name: "M75 Shoulder lesions" + codings: + - "M750" + - "M751" + - "M752" + - "M753" + - "M754" + - "M755" + - "M758" + - "M7581" + - "M759" + - name: "M79 Other soft tissue disorders, not elsewhere classified" + codings: + - "M790" + - "M7900" + - "M7901" + - "M7902" + - "M7903" + - "M7904" + - "M7905" + - "M7906" + - "M7907" + - "M7908" + - "M7909" + - "M791" + - "M7910" + - "M7911" + - "M7912" + - "M7913" + - "M7914" + - "M7915" + - "M7916" + - "M7917" + - "M7918" + - "M7919" + - "M792" + - "M7920" + - "M7921" + - "M7922" + - "M7923" + - "M7924" + - "M7925" + - "M7926" + - "M7927" + - "M7928" + - "M7929" + - "M793" + - "M7930" + - "M7931" + - "M7932" + - "M7933" + - "M7934" + - "M7935" + - "M7936" + - "M7937" + - "M7938" + - "M7939" + - "M794" + - "M7940" + - "M7941" + - "M7942" + - "M7943" + - "M7944" + - "M7945" + - "M7946" + - "M7947" + - "M7948" + - "M7949" + - "M795" + - "M7950" + - "M7951" + - "M7952" + - "M7953" + - "M7954" + - "M7955" + - "M7956" + - "M7957" + - "M7958" + - "M7959" + - "M796" + - "M7960" + - "M7961" + - "M7962" + - "M7963" + - "M7964" + - "M7965" + - "M7966" + - "M7967" + - "M7968" + - "M7969" + - "M797" + - "M7970" + - "M7971" + - "M7972" + - "M7973" + - "M7974" + - "M7975" + - "M7976" + - "M7977" + - "M7978" + - "M7979" + - "M798" + - "M7980" + - "M7981" + - "M7982" + - "M7983" + - "M7984" + - "M7985" + - "M7986" + - "M7987" + - "M7988" + - "M7989" + - "M799" + - "M7990" + - "M7991" + - "M7992" + - "M7993" + - "M7994" + - "M7995" + - "M7996" + - "M7997" + - "M7998" + - "M7999" + - name: "F40-F48 Neurotic, stress-related and somatoform disorders" + codings: + - "F411" + - "F412" + - "F413" + - "F418" + - "F419" + - "F42" + - "F420" + - "F421" + - "F422" + - "F428" + - "F429" + - "F43" + - "F430" + - "F431" + - "F432" + - "F438" + - "F439" + - "F44" + - "F440" + - "F441" + - "F442" + - "F443" + - "F444" + - "F445" + - "F446" + - "F447" + - "F448" + - "F449" + - "F45" + - "F450" + - "F451" + - "F452" + - "F453" + - "F454" + - "F458" + - "F459" + - "F48" + - "F480" + - "F481" + - "F488" + - "F489" + - "F40" + - "F400" + - "F401" + - "F402" + - "F408" + - "F409" + - "F41" + - "F410" + - name: "G90-G99 Other disorders of the nervous system" + codings: + - "G90" + - "G900" + - "G901" + - "G902" + - "G903" + - "G904" + - "G908" + - "G909" + - "G91" + - "G910" + - "G911" + - "G912" + - "G913" + - "G918" + - "G919" + - "G92" + - "G93" + - "G930" + - "G931" + - "G932" + - "G933" + - "G934" + - "G935" + - "G936" + - "G937" + - "G938" + - "G939" + - "G94" + - "G940" + - "G941" + - "G942" + - "G948" + - "G95" + - "G950" + - "G951" + - "G952" + - "G958" + - "G959" + - "G96" + - "G960" + - "G961" + - "G968" + - "G969" + - "G97" + - "G970" + - "G971" + - "G972" + - "G978" + - "G979" + - "G98" + - "G99" + - "G990" + - "G991" + - "G992" + - "G998" + - name: "M06 Other rheumatoid arthritis" + codings: + - "M0605" + - "M0606" + - "M0607" + - "M0608" + - "M0609" + - "M061" + - "M0610" + - "M0611" + - "M0612" + - "M0613" + - "M0614" + - "M0615" + - "M0616" + - "M0617" + - "M0618" + - "M0619" + - "M062" + - "M0620" + - "M0621" + - "M0622" + - "M0623" + - "M0624" + - "M0625" + - "M0626" + - "M0627" + - "M0628" + - "M0629" + - "M063" + - "M0630" + - "M0631" + - "M0632" + - "M0633" + - "M0634" + - "M0635" + - "M0636" + - "M0637" + - "M0638" + - "M0639" + - "M064" + - "M0640" + - "M0641" + - "M0642" + - "M0643" + - "M0644" + - "M0645" + - "M0646" + - "M0647" + - "M0648" + - "M0649" + - "M068" + - "M0680" + - "M0681" + - "M0682" + - "M0683" + - "M0684" + - "M0685" + - "M0686" + - "M0687" + - "M0688" + - "M0689" + - "M069" + - "M0690" + - "M0691" + - "M0692" + - "M0693" + - "M0694" + - "M0695" + - "M0696" + - "M0697" + - "M0698" + - "M0699" + - "M060" + - "M0600" + - "M0601" + - "M0602" + - "M0603" + - "M0604" + - name: "H33 Retinal detachments and breaks" + codings: + - "H330" + - "H331" + - "H332" + - "H333" + - "H334" + - "H335" + - name: "M05 Seropositive rheumatoid arthritis" + codings: + - "M050" + - "M0500" + - "M0501" + - "M0502" + - "M0503" + - "M0504" + - "M0505" + - "M0506" + - "M0507" + - "M0508" + - "M0509" + - "M051" + - "M0510" + - "M0511" + - "M0512" + - "M0513" + - "M0514" + - "M0515" + - "M0516" + - "M0517" + - "M0518" + - "M0519" + - "M052" + - "M0520" + - "M0521" + - "M0522" + - "M0523" + - "M0524" + - "M0525" + - "M0526" + - "M0527" + - "M0528" + - "M0529" + - "M053" + - "M0530" + - "M0531" + - "M0532" + - "M0533" + - "M0534" + - "M0535" + - "M0536" + - "M0537" + - "M0538" + - "M0539" + - "M058" + - "M0580" + - "M0581" + - "M0582" + - "M0583" + - "M0584" + - "M0585" + - "M0586" + - "M0587" + - "M0588" + - "M0589" + - "M059" + - "M0590" + - "M0591" + - "M0592" + - "M0593" + - "M0594" + - "M0595" + - "M0596" + - "M0597" + - "M0598" + - "M0599" + - name: "H36 Retinal disorders in diseases classified elsewhere" + codings: + - "H360" + - "H368" + - name: "H34 Retinal vascular occlusions" + codings: + - "H349" + - "H340" + - "H341" + - "H342" + - "H348" + - name: "H35 Other retinal disorders" + codings: + - "H350" + - "H351" + - "H352" + - "H353" + - "H354" + - "H355" + - "H356" + - "H357" + - "H358" + - "H359" + - name: "G31 Other degenerative diseases of nervous system, not elsewhere classified" + codings: + - "G319" + - "G310" + - "G311" + - "G312" + - "G318" + - name: "G35 Multiple sclerosis" + codings: + - "G35" + - name: "L60 Nail disorders" + codings: + - "L600" + - "L601" + - "L602" + - "L603" + - "L604" + - "L605" + - "L608" + - "L609" + - name: "E04 Other non-toxic goitre" + codings: + - "E042" + - "E048" + - "E049" + - "E040" + - "E041" + - name: "H40-H42 Glaucoma" + codings: + - "H40" + - "H400" + - "H401" + - "H402" + - "H403" + - "H404" + - "H405" + - "H406" + - "H408" + - "H409" + - "H42" + - "H420" + - "H428" + - name: "E03 Other hypothyroidism" + codings: + - "E030" + - "E031" + - "E032" + - "E033" + - "E034" + - "E035" + - "E038" + - "E039" + - name: "L02 Cutaneous abscess, furuncle and carbuncle" + codings: + - "L020" + - "L021" + - "L022" + - "L023" + - "L024" + - "L028" + - "L029" + - name: "K80-K87 Disorders of gallbladder, biliary tract and pancreas" + codings: + - "K860" + - "K861" + - "K862" + - "K863" + - "K868" + - "K869" + - "K87" + - "K870" + - "K871" + - "K80" + - "K800" + - "K801" + - "K802" + - "K803" + - "K8036" + - "K804" + - "K805" + - "K808" + - "K81" + - "K810" + - "K811" + - "K818" + - "K819" + - "K82" + - "K820" + - "K821" + - "K822" + - "K823" + - "K824" + - "K828" + - "K829" + - "K83" + - "K830" + - "K831" + - "K832" + - "K833" + - "K834" + - "K835" + - "K838" + - "K839" + - "K85" + - "K850" + - "K851" + - "K852" + - "K853" + - "K858" + - "K859" + - "K86" + - name: "L50-L54 Urticaria and erythema" + codings: + - "L50" + - "L500" + - "L501" + - "L502" + - "L503" + - "L504" + - "L505" + - "L506" + - "L508" + - "L509" + - "L51" + - "L510" + - "L511" + - "L512" + - "L518" + - "L519" + - "L52" + - "L53" + - "L530" + - "L531" + - "L532" + - "L533" + - "L538" + - "L539" + - "L54" + - "L540" + - "L548" + - name: "G80-G83 Cerebral palsy and other paralytic syndromes" + codings: + - "G80" + - "G800" + - "G801" + - "G802" + - "G803" + - "G804" + - "G808" + - "G809" + - "G81" + - "G810" + - "G811" + - "G819" + - "G82" + - "G820" + - "G821" + - "G822" + - "G823" + - "G824" + - "G825" + - "G83" + - "G830" + - "G831" + - "G832" + - "G833" + - "G834" + - "G835" + - "G838" + - "G839" + - name: "O32 Maternal care for known or suspected malpresentation of foetus" + codings: + - "O320" + - "O321" + - "O322" + - "O323" + - "O324" + - "O325" + - "O326" + - "O328" + - "O329" + - name: "O34 Maternal care for known or suspected abnormality of pelvic organs" + codings: + - "O346" + - "O347" + - "O348" + - "O349" + - "O340" + - "O341" + - "O342" + - "O343" + - "O344" + - "O345" + - name: "O36 Maternal care for other known or suspected foetal problems" + codings: + - "O360" + - "O361" + - "O362" + - "O363" + - "O364" + - "O365" + - "O366" + - "O367" + - "O368" + - "O369" + - name: "G81 Hemiplegia" + codings: + - "G810" + - "G811" + - "G819" + - name: "H65-H75 Diseases of middle ear and mastoid" + codings: + - "H65" + - "H650" + - "H651" + - "H652" + - "H653" + - "H654" + - "H659" + - "H66" + - "H660" + - "H661" + - "H662" + - "H663" + - "H664" + - "H669" + - "H67" + - "H670" + - "H671" + - "H678" + - "H68" + - "H680" + - "H681" + - "H69" + - "H690" + - "H698" + - "H699" + - "H70" + - "H700" + - "H701" + - "H702" + - "H708" + - "H709" + - "H71" + - "H72" + - "H720" + - "H721" + - "H722" + - "H728" + - "H729" + - "H73" + - "H730" + - "H731" + - "H738" + - "H739" + - "H74" + - "H740" + - "H741" + - "H742" + - "H743" + - "H744" + - "H748" + - "H749" + - "H75" + - "H750" + - "H758" + - name: "J06 Acute upper respiratory infections of multiple and unspecified sites" + codings: + - "J068" + - "J069" + - "J060" + - name: "D80-D89 Certain disorders involving the immune mechanism" + codings: + - "D80" + - "D800" + - "D801" + - "D802" + - "D803" + - "D804" + - "D805" + - "D806" + - "D807" + - "D808" + - "D809" + - "D81" + - "D810" + - "D811" + - "D812" + - "D813" + - "D814" + - "D815" + - "D816" + - "D817" + - "D818" + - "D819" + - "D82" + - "D820" + - "D821" + - "D822" + - "D823" + - "D824" + - "D828" + - "D829" + - "D83" + - "D830" + - "D831" + - "D832" + - "D838" + - "D839" + - "D84" + - "D840" + - "D841" + - "D848" + - "D849" + - "D86" + - "D860" + - "D861" + - "D862" + - "D863" + - "D868" + - "D869" + - "D89" + - "D890" + - "D891" + - "D892" + - "D893" + - "D898" + - "D899" + - name: "K50-K52 Noninfective enteritis and colitis" + codings: + - "K523" + - "K528" + - "K529" + - "K50" + - "K500" + - "K501" + - "K508" + - "K509" + - "K51" + - "K510" + - "K511" + - "K512" + - "K513" + - "K514" + - "K515" + - "K518" + - "K519" + - "K52" + - "K520" + - "K521" + - "K522" + - name: "K59 Other functional intestinal disorders" + codings: + - "K591" + - "K592" + - "K593" + - "K594" + - "K598" + - "K599" + - "K590" + - name: "K58 Irritable bowel syndrome" + codings: + - "K580" + - "K589" + - name: "K57 Diverticular disease of intestine" + codings: + - "K570" + - "K571" + - "K572" + - "K573" + - "K574" + - "K575" + - "K578" + - "K579" + - name: "K56 Paralytic ileus and intestinal obstruction without hernia" + codings: + - "K560" + - "K561" + - "K562" + - "K563" + - "K564" + - "K565" + - "K566" + - "K567" + - name: "K55 Vascular disorders of intestine" + codings: + - "K559" + - "K550" + - "K551" + - "K552" + - "K558" + - name: "K52 Other non-infective gastro-enteritis and colitis" + codings: + - "K523" + - "K528" + - "K529" + - "K520" + - "K521" + - "K522" + - name: "J60-J70 Lung diseases due to external agents" + codings: + - "J60" + - "J61" + - "J62" + - "J620" + - "J628" + - "J63" + - "J630" + - "J631" + - "J632" + - "J633" + - "J634" + - "J635" + - "J638" + - "J64" + - "J65" + - "J66" + - "J660" + - "J661" + - "J662" + - "J668" + - "J67" + - "J670" + - "J671" + - "J672" + - "J673" + - "J674" + - "J675" + - "J676" + - "J677" + - "J678" + - "J679" + - "J68" + - "J680" + - "J681" + - "J682" + - "J683" + - "J684" + - "J688" + - "J689" + - "J69" + - "J690" + - "J691" + - "J698" + - "J70" + - "J700" + - "J701" + - "J702" + - "J703" + - "J704" + - "J708" + - "J709" + - name: "K50 Crohn's disease [regional enteritis]" + codings: + - "K501" + - "K508" + - "K509" + - "K500" + - name: "E78 Disorders of lipoprotein metabolism and other lipidaemias" + codings: + - "E780" + - "E781" + - "E782" + - "E783" + - "E784" + - "E785" + - "E786" + - "E788" + - "E789" + - name: "G70-G73 Diseases of myoneural junction and muscle" + codings: + - "G701" + - "G702" + - "G708" + - "G709" + - "G71" + - "G710" + - "G711" + - "G712" + - "G713" + - "G718" + - "G719" + - "G72" + - "G720" + - "G721" + - "G722" + - "G723" + - "G724" + - "G728" + - "G729" + - "G73" + - "G730" + - "G731" + - "G732" + - "G733" + - "G734" + - "G735" + - "G736" + - "G737" + - "G70" + - "G700" + - name: "N10-N16 Renal tubulo-interstitial diseases" + codings: + - "N10" + - "N11" + - "N110" + - "N111" + - "N118" + - "N119" + - "N12" + - "N13" + - "N130" + - "N131" + - "N132" + - "N133" + - "N134" + - "N135" + - "N136" + - "N137" + - "N138" + - "N139" + - "N14" + - "N140" + - "N141" + - "N142" + - "N143" + - "N144" + - "N15" + - "N150" + - "N151" + - "N158" + - "N159" + - "N16" + - "N160" + - "N161" + - "N162" + - "N163" + - "N164" + - "N165" + - "N168" + - name: "N85 Other noninflammatory disorders of uterus, except cervix" + codings: + - "N850" + - "N851" + - "N852" + - "N853" + - "N854" + - "N855" + - "N856" + - "N857" + - "N858" + - "N859" + - name: "N84 Polyp of female genital tract" + codings: + - "N843" + - "N848" + - "N849" + - "N840" + - "N841" + - "N842" + - name: "N87 Dysplasia of cervix uteri" + codings: + - "N870" + - "N871" + - "N872" + - "N879" + - name: "N86 Erosion and ectropion of cervix uteri" + codings: + - "N86" + - name: "N81 Female genital prolapse" + codings: + - "N811" + - "N812" + - "N813" + - "N814" + - "N815" + - "N816" + - "N818" + - "N819" + - "N810" + - name: "N80 Endometriosis" + codings: + - "N800" + - "N801" + - "N802" + - "N803" + - "N804" + - "N805" + - "N806" + - "N808" + - "N809" + - name: "N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament" + codings: + - "N830" + - "N831" + - "N832" + - "N833" + - "N834" + - "N835" + - "N836" + - "N837" + - "N838" + - "N839" + - name: "N89 Other noninflammatory disorders of vagina" + codings: + - "N893" + - "N894" + - "N895" + - "N896" + - "N897" + - "N898" + - "N899" + - "N890" + - "N891" + - "N892" + - name: "N88 Other noninflammatory disorders of cervix uteri" + codings: + - "N880" + - "N881" + - "N882" + - "N883" + - "N884" + - "N888" + - "N889" + - name: "H53-H54 Visual disturbances and blindness" + codings: + - "H53" + - "H530" + - "H531" + - "H532" + - "H533" + - "H534" + - "H535" + - "H536" + - "H538" + - "H539" + - "H54" + - "H540" + - "H541" + - "H542" + - "H543" + - "H544" + - "H545" + - "H546" + - "H547" + - "H549" + - name: "F31 Bipolar affective disorder" + codings: + - "F310" + - "F311" + - "F312" + - "F313" + - "F314" + - "F315" + - "F316" + - "F317" + - "F318" + - "F319" + - name: "F32 Depressive episode" + codings: + - "F320" + - "F321" + - "F322" + - "F323" + - "F328" + - "F329" + - name: "F33 Recurrent depressive disorder" + codings: + - "F330" + - "F331" + - "F332" + - "F333" + - "F334" + - "F338" + - "F339" + - name: "D69 Purpura and other haemorrhagic conditions" + codings: + - "D698" + - "D699" + - "D690" + - "D691" + - "D692" + - "D693" + - "D694" + - "D695" + - "D696" + - name: "D68 Other coagulation defects" + codings: + - "D680" + - "D681" + - "D682" + - "D683" + - "D684" + - "D685" + - "D686" + - "D688" + - "D689" + - name: "D64 Other anaemias" + codings: + - "D640" + - "D641" + - "D642" + - "D643" + - "D644" + - "D648" + - "D649" + - name: "D63 Anaemia in chronic diseases classified elsewhere" + codings: + - "D630" + - "D631" + - "D638" + - name: "N00-N08 Glomerular diseases" + codings: + - "N069" + - "N07" + - "N070" + - "N071" + - "N072" + - "N073" + - "N074" + - "N075" + - "N076" + - "N077" + - "N078" + - "N079" + - "N08" + - "N080" + - "N081" + - "N082" + - "N083" + - "N084" + - "N085" + - "N088" + - "N00" + - "N000" + - "N001" + - "N002" + - "N003" + - "N004" + - "N005" + - "N006" + - "N007" + - "N008" + - "N009" + - "N01" + - "N010" + - "N011" + - "N012" + - "N013" + - "N014" + - "N015" + - "N016" + - "N017" + - "N018" + - "N019" + - "N02" + - "N020" + - "N021" + - "N022" + - "N023" + - "N024" + - "N025" + - "N026" + - "N027" + - "N028" + - "N029" + - "N03" + - "N030" + - "N031" + - "N032" + - "N033" + - "N034" + - "N035" + - "N036" + - "N037" + - "N038" + - "N039" + - "N04" + - "N040" + - "N041" + - "N042" + - "N043" + - "N044" + - "N045" + - "N046" + - "N047" + - "N048" + - "N049" + - "N05" + - "N050" + - "N051" + - "N052" + - "N053" + - "N054" + - "N055" + - "N056" + - "N057" + - "N058" + - "N059" + - "N06" + - "N060" + - "N061" + - "N062" + - "N063" + - "N064" + - "N065" + - "N066" + - "N067" + - "N068" + - name: "I64 Stroke, not specified as haemorrhage or infarction" + codings: + - "I64" + - name: "N39 Other disorders of urinary system" + codings: + - "N390" + - "N391" + - "N392" + - "N393" + - "N394" + - "N398" + - "N399" + - name: "I67 Other cerebrovascular diseases" + codings: + - "I672" + - "I673" + - "I674" + - "I675" + - "I676" + - "I677" + - "I678" + - "I679" + - "I670" + - "I671" + - name: "B00-B09 Viral infections characterized by skin and mucous membrane lesions" + codings: + - "B02" + - "B020" + - "B021" + - "B022" + - "B023" + - "B027" + - "B028" + - "B029" + - "B03" + - "B04" + - "B05" + - "B050" + - "B051" + - "B052" + - "B053" + - "B054" + - "B058" + - "B059" + - "B06" + - "B060" + - "B068" + - "B069" + - "B07" + - "B08" + - "B080" + - "B081" + - "B082" + - "B083" + - "B084" + - "B085" + - "B088" + - "B09" + - "B00" + - "B000" + - "B001" + - "B002" + - "B003" + - "B004" + - "B005" + - "B007" + - "B008" + - "B009" + - "B01" + - "B010" + - "B011" + - "B012" + - "B018" + - "B019" + - name: "I61 Intracerebral haemorrhage" + codings: + - "I610" + - "I611" + - "I612" + - "I613" + - "I614" + - "I615" + - "I616" + - "I618" + - "I619" + - name: "I63 Cerebral infarction" + codings: + - "I630" + - "I631" + - "I632" + - "I633" + - "I634" + - "I635" + - "I636" + - "I638" + - "I639" + - name: "N30 Cystitis" + codings: + - "N300" + - "N301" + - "N302" + - "N303" + - "N304" + - "N308" + - "N309" + - name: "N31 Neuromuscular dysfunction of bladder, not elsewhere classified" + codings: + - "N310" + - "N311" + - "N312" + - "N318" + - "N319" + - name: "N32 Other disorders of bladder" + codings: + - "N320" + - "N321" + - "N322" + - "N323" + - "N324" + - "N328" + - "N329" + - name: "O80-O84 Delivery" + codings: + - "O80" + - "O800" + - "O801" + - "O808" + - "O809" + - "O81" + - "O810" + - "O811" + - "O812" + - "O813" + - "O814" + - "O815" + - "O82" + - "O820" + - "O821" + - "O822" + - "O828" + - "O829" + - "O83" + - "O830" + - "O831" + - "O832" + - "O833" + - "O834" + - "O838" + - "O839" + - "O84" + - "O840" + - "O841" + - "O842" + - "O848" + - "O849" + - name: "N36 Other disorders of urethra" + codings: + - "N360" + - "N361" + - "N362" + - "N363" + - "N368" + - "N369" + - name: "N20-N23 Urolithiasis" + codings: + - "N20" + - "N200" + - "N201" + - "N202" + - "N209" + - "N21" + - "N210" + - "N211" + - "N218" + - "N219" + - "N22" + - "N220" + - "N228" + - "N23" + - name: "H02 Other disorders of eyelid" + codings: + - "H028" + - "H029" + - "H020" + - "H021" + - "H022" + - "H023" + - "H024" + - "H025" + - "H026" + - "H027" + - name: "H01 Other inflammation of eyelid" + codings: + - "H010" + - "H011" + - "H018" + - "H019" + - name: "H00 Hordeolum and chalazion" + codings: + - "H000" + - "H001" + - name: "M31 Other necrotising vasculopathies" + codings: + - "M310" + - "M311" + - "M312" + - "M313" + - "M314" + - "M315" + - "M316" + - "M317" + - "M318" + - "M319" + - name: "H04 Disorders of lachrymal system" + codings: + - "H040" + - "H041" + - "H042" + - "H043" + - "H044" + - "H045" + - "H046" + - "H048" + - "H049" + - name: "M00-M03 Infectious arthropathies" + codings: + - "M00" + - "M000" + - "M0000" + - "M0001" + - "M0002" + - "M0003" + - "M0004" + - "M0005" + - "M0006" + - "M0007" + - "M0008" + - "M0009" + - "M001" + - "M0010" + - "M0011" + - "M0012" + - "M0013" + - "M0014" + - "M0015" + - "M0016" + - "M0017" + - "M0018" + - "M0019" + - "M002" + - "M0020" + - "M0021" + - "M0022" + - "M0023" + - "M0024" + - "M0025" + - "M0026" + - "M0027" + - "M0028" + - "M0029" + - "M008" + - "M0080" + - "M0081" + - "M0082" + - "M0083" + - "M0084" + - "M0085" + - "M0086" + - "M0087" + - "M0088" + - "M0089" + - "M009" + - "M0090" + - "M0091" + - "M0092" + - "M0093" + - "M0094" + - "M0095" + - "M0096" + - "M0097" + - "M0098" + - "M0099" + - "M01" + - "M010" + - "M0100" + - "M0101" + - "M0102" + - "M0103" + - "M0104" + - "M0105" + - "M0106" + - "M0107" + - "M0108" + - "M0109" + - "M011" + - "M0110" + - "M0111" + - "M0112" + - "M0113" + - "M0114" + - "M0115" + - "M0116" + - "M0117" + - "M0118" + - "M0119" + - "M012" + - "M0120" + - "M0121" + - "M0122" + - "M0123" + - "M0124" + - "M0125" + - "M0126" + - "M0127" + - "M0128" + - "M0129" + - "M013" + - "M0130" + - "M0131" + - "M0132" + - "M0133" + - "M0134" + - "M0135" + - "M0136" + - "M0137" + - "M0138" + - "M0139" + - "M014" + - "M0140" + - "M0141" + - "M0142" + - "M0143" + - "M0144" + - "M0145" + - "M0146" + - "M0147" + - "M0148" + - "M0149" + - "M015" + - "M0150" + - "M0151" + - "M0152" + - "M0153" + - "M0154" + - "M0155" + - "M0156" + - "M0157" + - "M0158" + - "M0159" + - "M016" + - "M0160" + - "M0161" + - "M0162" + - "M0163" + - "M0164" + - "M0165" + - "M0166" + - "M0167" + - "M0168" + - "M0169" + - "M018" + - "M0180" + - "M0181" + - "M0182" + - "M0183" + - "M0184" + - "M0185" + - "M0186" + - "M0187" + - "M0188" + - "M0189" + - "M02" + - "M020" + - "M0200" + - "M0201" + - "M0202" + - "M0203" + - "M0204" + - "M0205" + - "M0206" + - "M0207" + - "M0208" + - "M0209" + - "M021" + - "M0210" + - "M0211" + - "M0212" + - "M0213" + - "M0214" + - "M0215" + - "M0216" + - "M0217" + - "M0218" + - "M0219" + - "M022" + - "M0220" + - "M0221" + - "M0222" + - "M0223" + - "M0224" + - "M0225" + - "M0226" + - "M0227" + - "M0228" + - "M0229" + - "M023" + - "M0230" + - "M0231" + - "M0232" + - "M0233" + - "M0234" + - "M0235" + - "M0236" + - "M0237" + - "M0238" + - "M0239" + - "M028" + - "M0280" + - "M0281" + - "M0282" + - "M0283" + - "M0284" + - "M0285" + - "M0286" + - "M0287" + - "M0288" + - "M0289" + - "M029" + - "M0290" + - "M0291" + - "M0292" + - "M0293" + - "M0294" + - "M0295" + - "M0296" + - "M0297" + - "M0298" + - "M0299" + - "M03" + - "M030" + - "M0300" + - "M0301" + - "M0302" + - "M0303" + - "M0304" + - "M0305" + - "M0306" + - "M0307" + - "M0308" + - "M0309" + - "M031" + - "M0310" + - "M0311" + - "M0312" + - "M0313" + - "M0314" + - "M0315" + - "M0316" + - "M0317" + - "M0318" + - "M0319" + - "M032" + - "M0320" + - "M0321" + - "M0322" + - "M0323" + - "M0324" + - "M0325" + - "M0326" + - "M0327" + - "M0328" + - "M0329" + - "M036" + - "M0360" + - "M0361" + - "M0362" + - "M0363" + - "M0364" + - "M0365" + - "M0366" + - "M0367" + - "M0368" + - "M0369" + - name: "O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems" + codings: + - "O30" + - "O300" + - "O301" + - "O302" + - "O308" + - "O309" + - "O31" + - "O310" + - "O311" + - "O312" + - "O318" + - "O32" + - "O320" + - "O321" + - "O322" + - "O323" + - "O324" + - "O325" + - "O326" + - "O328" + - "O329" + - "O33" + - "O330" + - "O331" + - "O332" + - "O333" + - "O334" + - "O335" + - "O336" + - "O337" + - "O338" + - "O339" + - "O34" + - "O340" + - "O341" + - "O342" + - "O343" + - "O344" + - "O345" + - "O346" + - "O347" + - "O348" + - "O349" + - "O35" + - "O350" + - "O351" + - "O352" + - "O353" + - "O354" + - "O355" + - "O356" + - "O357" + - "O358" + - "O359" + - "O36" + - "O360" + - "O361" + - "O362" + - "O363" + - "O364" + - "O365" + - "O366" + - "O367" + - "O368" + - "O369" + - "O40" + - "O41" + - "O410" + - "O411" + - "O418" + - "O419" + - "O42" + - "O420" + - "O421" + - "O422" + - "O429" + - "O43" + - "O430" + - "O431" + - "O432" + - "O438" + - "O439" + - "O44" + - "O440" + - "O441" + - "O45" + - "O450" + - "O458" + - "O459" + - "O46" + - "O460" + - "O468" + - "O469" + - "O47" + - "O470" + - "O471" + - "O479" + - "O48" + - name: "N80-N98 Noninflammatory disorders of female genital tract" + codings: + - "N80" + - "N800" + - "N801" + - "N802" + - "N803" + - "N804" + - "N805" + - "N806" + - "N808" + - "N809" + - "N81" + - "N810" + - "N811" + - "N812" + - "N813" + - "N814" + - "N815" + - "N816" + - "N818" + - "N819" + - "N82" + - "N820" + - "N821" + - "N822" + - "N823" + - "N824" + - "N825" + - "N828" + - "N829" + - "N83" + - "N830" + - "N831" + - "N832" + - "N833" + - "N834" + - "N835" + - "N836" + - "N837" + - "N838" + - "N839" + - "N84" + - "N840" + - "N841" + - "N842" + - "N843" + - "N848" + - "N849" + - "N85" + - "N850" + - "N851" + - "N852" + - "N853" + - "N854" + - "N855" + - "N856" + - "N857" + - "N858" + - "N859" + - "N86" + - "N87" + - "N870" + - "N871" + - "N872" + - "N879" + - "N88" + - "N880" + - "N881" + - "N882" + - "N883" + - "N884" + - "N888" + - "N889" + - "N89" + - "N890" + - "N891" + - "N892" + - "N893" + - "N894" + - "N895" + - "N896" + - "N897" + - "N898" + - "N899" + - "N90" + - "N900" + - "N901" + - "N902" + - "N903" + - "N904" + - "N905" + - "N906" + - "N907" + - "N908" + - "N909" + - "N91" + - "N910" + - "N911" + - "N912" + - "N913" + - "N914" + - "N915" + - "N92" + - "N920" + - "N921" + - "N922" + - "N923" + - "N924" + - "N925" + - "N926" + - "N93" + - "N930" + - "N938" + - "N939" + - "N94" + - "N940" + - "N941" + - "N942" + - "N943" + - "N944" + - "N945" + - "N946" + - "N948" + - "N949" + - "N95" + - "N950" + - "N951" + - "N952" + - "N953" + - "N958" + - "N959" + - "N96" + - "N97" + - "N970" + - "N971" + - "N972" + - "N973" + - "N974" + - "N978" + - "N979" + - "N98" + - "N980" + - "N981" + - "N982" + - "N983" + - "N988" + - "N989" + - name: "I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction" + codings: + - "I650" + - "I651" + - "I652" + - "I653" + - "I658" + - "I659" + - name: "L40 Psoriasis" + codings: + - "L400" + - "L401" + - "L402" + - "L403" + - "L404" + - "L405" + - "L408" + - "L409" + - name: "I60 Subarachnoid haemorrhage" + codings: + - "I600" + - "I601" + - "I602" + - "I603" + - "I604" + - "I605" + - "I606" + - "I607" + - "I608" + - "I609" + - name: "H72 Perforation of tympanic membrane" + codings: + - "H729" + - "H720" + - "H721" + - "H722" + - "H728" + - name: "M45-M49 Spondylopathies" + codings: + - "M4913" + - "M4914" + - "M4915" + - "M4916" + - "M4917" + - "M4918" + - "M4919" + - "M492" + - "M4920" + - "M4921" + - "M4922" + - "M4923" + - "M4924" + - "M4925" + - "M4926" + - "M4927" + - "M4928" + - "M4929" + - "M493" + - "M4930" + - "M4931" + - "M4932" + - "M4933" + - "M4934" + - "M4935" + - "M4936" + - "M4937" + - "M4938" + - "M4939" + - "M494" + - "M4940" + - "M4941" + - "M4942" + - "M4943" + - "M4944" + - "M4945" + - "M4946" + - "M4947" + - "M4948" + - "M4949" + - "M495" + - "M4950" + - "M4951" + - "M4952" + - "M4953" + - "M4954" + - "M4955" + - "M4956" + - "M4957" + - "M4958" + - "M4959" + - "M498" + - "M4980" + - "M4981" + - "M4982" + - "M4983" + - "M4984" + - "M4985" + - "M4986" + - "M4987" + - "M4988" + - "M4989" + - "M45" + - "M45X0" + - "M45X1" + - "M45X2" + - "M45X3" + - "M45X4" + - "M45X5" + - "M45X6" + - "M45X7" + - "M45X8" + - "M45X9" + - "M46" + - "M460" + - "M4600" + - "M4601" + - "M4602" + - "M4603" + - "M4604" + - "M4605" + - "M4606" + - "M4607" + - "M4608" + - "M4609" + - "M461" + - "M4610" + - "M4611" + - "M4612" + - "M4613" + - "M4614" + - "M4615" + - "M4616" + - "M4617" + - "M4618" + - "M4619" + - "M462" + - "M4620" + - "M4621" + - "M4622" + - "M4623" + - "M4624" + - "M4625" + - "M4626" + - "M4627" + - "M4628" + - "M4629" + - "M463" + - "M4630" + - "M4631" + - "M4632" + - "M4633" + - "M4634" + - "M4635" + - "M4636" + - "M4637" + - "M4638" + - "M4639" + - "M464" + - "M4640" + - "M4641" + - "M4642" + - "M4643" + - "M4644" + - "M4645" + - "M4646" + - "M4647" + - "M4648" + - "M4649" + - "M465" + - "M4650" + - "M4651" + - "M4652" + - "M4653" + - "M4654" + - "M4655" + - "M4656" + - "M4657" + - "M4658" + - "M4659" + - "M468" + - "M4680" + - "M4681" + - "M4682" + - "M4683" + - "M4684" + - "M4685" + - "M4686" + - "M4687" + - "M4688" + - "M4689" + - "M469" + - "M4690" + - "M4691" + - "M4692" + - "M4693" + - "M4694" + - "M4695" + - "M4696" + - "M4697" + - "M4698" + - "M4699" + - "M47" + - "M470" + - "M4700" + - "M4701" + - "M4702" + - "M4703" + - "M4704" + - "M4705" + - "M4706" + - "M4707" + - "M4708" + - "M4709" + - "M471" + - "M4710" + - "M4711" + - "M4712" + - "M4713" + - "M4714" + - "M4715" + - "M4716" + - "M4717" + - "M4718" + - "M4719" + - "M472" + - "M4720" + - "M4721" + - "M4722" + - "M4723" + - "M4724" + - "M4725" + - "M4726" + - "M4727" + - "M4728" + - "M4729" + - "M478" + - "M4780" + - "M4781" + - "M4782" + - "M4783" + - "M4784" + - "M4785" + - "M4786" + - "M4787" + - "M4788" + - "M4789" + - "M479" + - "M4790" + - "M4791" + - "M4792" + - "M4793" + - "M4794" + - "M4795" + - "M4796" + - "M4797" + - "M4798" + - "M4799" + - "M48" + - "M480" + - "M4800" + - "M4801" + - "M4802" + - "M4803" + - "M4804" + - "M4805" + - "M4806" + - "M4807" + - "M4808" + - "M4809" + - "M481" + - "M4810" + - "M4811" + - "M4812" + - "M4813" + - "M4814" + - "M4815" + - "M4816" + - "M4817" + - "M4818" + - "M4819" + - "M482" + - "M4820" + - "M4821" + - "M4822" + - "M4823" + - "M4824" + - "M4825" + - "M4826" + - "M4827" + - "M4828" + - "M4829" + - "M483" + - "M4830" + - "M4831" + - "M4832" + - "M4833" + - "M4834" + - "M4835" + - "M4836" + - "M4837" + - "M4838" + - "M4839" + - "M484" + - "M4840" + - "M4841" + - "M4842" + - "M4843" + - "M4844" + - "M4845" + - "M4846" + - "M4847" + - "M4848" + - "M4849" + - "M485" + - "M4850" + - "M4851" + - "M4852" + - "M4853" + - "M4854" + - "M4855" + - "M4856" + - "M4857" + - "M4858" + - "M4859" + - "M488" + - "M4880" + - "M4881" + - "M4882" + - "M4883" + - "M4884" + - "M4885" + - "M4886" + - "M4887" + - "M4888" + - "M4889" + - "M489" + - "M4890" + - "M4891" + - "M4892" + - "M4893" + - "M4894" + - "M4895" + - "M4896" + - "M4897" + - "M4898" + - "M4899" + - "M49" + - "M490" + - "M4900" + - "M4901" + - "M4902" + - "M4903" + - "M4904" + - "M4905" + - "M4906" + - "M4907" + - "M4908" + - "M4909" + - "M491" + - "M4910" + - "M4911" + - "M4912" + - name: "K21 Gastro-oesophageal reflux disease" + codings: + - "K210" + - "K219" + - name: "H90 Conductive and sensorineural hearing loss" + codings: + - "H900" + - "H901" + - "H902" + - "H903" + - "H904" + - "H905" + - "H906" + - "H907" + - "H908" + - name: "H91 Other hearing loss" + codings: + - "H910" + - "H911" + - "H912" + - "H913" + - "H918" + - "H919" + - name: "H92 Otalgia and effusion of ear" + codings: + - "H920" + - "H921" + - "H922" + - name: "H93 Other disorders of ear, not elsewhere classified" + codings: + - "H933" + - "H938" + - "H939" + - "H930" + - "H931" + - "H932" + - name: "J80-J84 Other respiratory diseases principally affecting the interstitium" + codings: + - "J80" + - "J81" + - "J82" + - "J84" + - "J840" + - "J841" + - "J848" + - "J849" + - name: "I95-I99 Other and unspecified disorders of the circulatory system" + codings: + - "I980" + - "I981" + - "I982" + - "I983" + - "I988" + - "I99" + - "I95" + - "I950" + - "I951" + - "I952" + - "I958" + - "I959" + - "I97" + - "I970" + - "I971" + - "I972" + - "I978" + - "I979" + - "I98" + - name: "L97 Ulcer of lower limb, not elsewhere classified" + codings: + - "L97" + - name: "L90 Atrophic disorders of skin" + codings: + - "L901" + - "L902" + - "L903" + - "L904" + - "L905" + - "L906" + - "L908" + - "L909" + - "L900" + - name: "L91 Hypertrophic disorders of skin" + codings: + - "L910" + - "L918" + - "L919" + - name: "L92 Granulomatous disorders of skin and subcutaneous tissue" + codings: + - "L920" + - "L921" + - "L922" + - "L923" + - "L928" + - "L929" + - name: "L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified" + codings: + - "L980" + - "L981" + - "L982" + - "L983" + - "L984" + - "L985" + - "L986" + - "L987" + - "L988" + - "L989" + - name: "N17-N19 Renal failure" + codings: + - "N180" + - "N181" + - "N182" + - "N183" + - "N184" + - "N185" + - "N188" + - "N189" + - "N19" + - "N17" + - "N170" + - "N171" + - "N172" + - "N178" + - "N179" + - "N18" + - name: "M20-M25 Other joint disorders" + codings: + - "M20" + - "M200" + - "M201" + - "M202" + - "M203" + - "M204" + - "M205" + - "M206" + - "M21" + - "M210" + - "M2100" + - "M2101" + - "M2102" + - "M2103" + - "M2104" + - "M2105" + - "M2106" + - "M2107" + - "M2108" + - "M2109" + - "M211" + - "M2110" + - "M2111" + - "M2112" + - "M2113" + - "M2114" + - "M2115" + - "M2116" + - "M2117" + - "M2118" + - "M2119" + - "M212" + - "M2120" + - "M2121" + - "M2122" + - "M2123" + - "M2124" + - "M2125" + - "M2126" + - "M2127" + - "M2128" + - "M2129" + - "M213" + - "M2130" + - "M2131" + - "M2132" + - "M2133" + - "M2134" + - "M2135" + - "M2136" + - "M2137" + - "M2138" + - "M2139" + - "M214" + - "M2140" + - "M2141" + - "M2142" + - "M2143" + - "M2144" + - "M2145" + - "M2146" + - "M2147" + - "M2148" + - "M2149" + - "M215" + - "M2150" + - "M2151" + - "M2152" + - "M2153" + - "M2154" + - "M2155" + - "M2156" + - "M2157" + - "M2158" + - "M2159" + - "M216" + - "M2160" + - "M2161" + - "M2162" + - "M2163" + - "M2164" + - "M2165" + - "M2166" + - "M2167" + - "M2168" + - "M2169" + - "M217" + - "M2170" + - "M2171" + - "M2172" + - "M2173" + - "M2174" + - "M2175" + - "M2176" + - "M2177" + - "M2178" + - "M2179" + - "M218" + - "M2180" + - "M2181" + - "M2182" + - "M2183" + - "M2184" + - "M2185" + - "M2186" + - "M2187" + - "M2188" + - "M2189" + - "M219" + - "M2190" + - "M2191" + - "M2192" + - "M2193" + - "M2194" + - "M2195" + - "M2196" + - "M2197" + - "M2198" + - "M2199" + - "M22" + - "M220" + - "M221" + - "M2210" + - "M222" + - "M223" + - "M224" + - "M228" + - "M229" + - "M23" + - "M230" + - "M2300" + - "M2301" + - "M2302" + - "M2303" + - "M2304" + - "M2305" + - "M2306" + - "M2307" + - "M2309" + - "M231" + - "M2310" + - "M2311" + - "M2312" + - "M2313" + - "M2314" + - "M2315" + - "M2316" + - "M2317" + - "M2319" + - "M232" + - "M2320" + - "M2321" + - "M2322" + - "M2323" + - "M2324" + - "M2325" + - "M2326" + - "M2327" + - "M2329" + - "M233" + - "M2330" + - "M2331" + - "M2332" + - "M2333" + - "M2334" + - "M2335" + - "M2336" + - "M2337" + - "M2339" + - "M234" + - "M2340" + - "M2341" + - "M2342" + - "M2343" + - "M2344" + - "M2345" + - "M2346" + - "M2347" + - "M2349" + - "M235" + - "M2350" + - "M2351" + - "M2352" + - "M2353" + - "M2354" + - "M2355" + - "M2356" + - "M2357" + - "M2359" + - "M236" + - "M2360" + - "M2361" + - "M2362" + - "M2363" + - "M2364" + - "M2365" + - "M2366" + - "M2367" + - "M2369" + - "M238" + - "M2380" + - "M2381" + - "M2382" + - "M2383" + - "M2384" + - "M2385" + - "M2386" + - "M2387" + - "M2389" + - "M239" + - "M2390" + - "M2391" + - "M2392" + - "M2393" + - "M2394" + - "M2395" + - "M2396" + - "M2397" + - "M2399" + - "M24" + - "M240" + - "M2400" + - "M2401" + - "M2402" + - "M2403" + - "M2404" + - "M2405" + - "M2406" + - "M2407" + - "M2408" + - "M2409" + - "M241" + - "M2410" + - "M2411" + - "M2412" + - "M2413" + - "M2414" + - "M2415" + - "M2416" + - "M2417" + - "M2418" + - "M2419" + - "M242" + - "M2420" + - "M2421" + - "M2422" + - "M2423" + - "M2424" + - "M2425" + - "M2426" + - "M2427" + - "M2428" + - "M2429" + - "M243" + - "M2430" + - "M2431" + - "M2432" + - "M2433" + - "M2434" + - "M2435" + - "M2436" + - "M2437" + - "M2438" + - "M2439" + - "M244" + - "M2440" + - "M2441" + - "M2442" + - "M2443" + - "M2444" + - "M2445" + - "M2446" + - "M2447" + - "M2448" + - "M2449" + - "M245" + - "M2450" + - "M2451" + - "M2452" + - "M2453" + - "M2454" + - "M2455" + - "M2456" + - "M2457" + - "M2458" + - "M2459" + - "M246" + - "M2460" + - "M2461" + - "M2462" + - "M2463" + - "M2464" + - "M2465" + - "M2466" + - "M2467" + - "M2468" + - "M2469" + - "M247" + - "M2470" + - "M2471" + - "M2472" + - "M2473" + - "M2474" + - "M2475" + - "M2476" + - "M2477" + - "M2478" + - "M2479" + - "M248" + - "M2480" + - "M2481" + - "M2482" + - "M2483" + - "M2484" + - "M2485" + - "M2486" + - "M2487" + - "M2488" + - "M2489" + - "M249" + - "M2490" + - "M2491" + - "M2492" + - "M2493" + - "M2494" + - "M2495" + - "M2496" + - "M2497" + - "M2498" + - "M2499" + - "M25" + - "M250" + - "M2500" + - "M2501" + - "M2502" + - "M2503" + - "M2504" + - "M2505" + - "M2506" + - "M2507" + - "M2508" + - "M2509" + - "M251" + - "M2510" + - "M2511" + - "M2512" + - "M2513" + - "M2514" + - "M2515" + - "M2516" + - "M2517" + - "M2518" + - "M2519" + - "M252" + - "M2520" + - "M2521" + - "M2522" + - "M2523" + - "M2524" + - "M2525" + - "M2526" + - "M2527" + - "M2528" + - "M2529" + - "M253" + - "M2530" + - "M2531" + - "M2532" + - "M2533" + - "M2534" + - "M2535" + - "M2536" + - "M2537" + - "M2538" + - "M2539" + - "M254" + - "M2540" + - "M2541" + - "M2542" + - "M2543" + - "M2544" + - "M2545" + - "M2546" + - "M2547" + - "M2548" + - "M2549" + - "M255" + - "M2550" + - "M2551" + - "M2552" + - "M2553" + - "M2554" + - "M2555" + - "M2556" + - "M2557" + - "M2558" + - "M2559" + - "M256" + - "M2560" + - "M2561" + - "M2562" + - "M2563" + - "M2564" + - "M2565" + - "M2566" + - "M2567" + - "M2568" + - "M2569" + - "M257" + - "M2570" + - "M2571" + - "M2572" + - "M2573" + - "M2574" + - "M2575" + - "M2576" + - "M2577" + - "M2578" + - "M2579" + - "M258" + - "M2580" + - "M2581" + - "M2582" + - "M2583" + - "M2584" + - "M2585" + - "M2586" + - "M2587" + - "M2588" + - "M2589" + - "M259" + - "M2590" + - "M2591" + - "M2592" + - "M2593" + - "M2594" + - "M2595" + - "M2596" + - "M2597" + - "M2598" + - "M2599" + - "M30" + - "M300" + - "M301" + - "M302" + - "M303" + - "M308" + - "M31" + - "M310" + - "M311" + - "M312" + - "M313" + - "M314" + - "M315" + - "M316" + - "M317" + - "M318" + - "M319" + - "M32" + - "M320" + - "M321" + - "M328" + - "M329" + - "M3290" + - "M33" + - "M330" + - "M331" + - "M332" + - "M339" + - "M34" + - "M340" + - "M341" + - "M342" + - "M348" + - "M349" + - "M35" + - "M350" + - "M351" + - "M352" + - "M353" + - "M354" + - "M355" + - "M356" + - "M357" + - "M358" + - "M359" + - "M3599" + - "M36" + - "M360" + - "M361" + - "M362" + - "M363" + - "M364" + - "M368" + - name: "E70-E90 Metabolic disorders" + codings: + - "E70" + - "E700" + - "E701" + - "E702" + - "E703" + - "E708" + - "E709" + - "E71" + - "E710" + - "E711" + - "E712" + - "E713" + - "E72" + - "E720" + - "E721" + - "E722" + - "E723" + - "E724" + - "E725" + - "E728" + - "E729" + - "E73" + - "E730" + - "E731" + - "E738" + - "E739" + - "E74" + - "E740" + - "E741" + - "E742" + - "E743" + - "E744" + - "E748" + - "E749" + - "E75" + - "E750" + - "E751" + - "E752" + - "E753" + - "E754" + - "E755" + - "E756" + - "E76" + - "E760" + - "E761" + - "E762" + - "E763" + - "E768" + - "E769" + - "E77" + - "E770" + - "E771" + - "E778" + - "E779" + - "E78" + - "E780" + - "E781" + - "E782" + - "E783" + - "E784" + - "E785" + - "E786" + - "E788" + - "E789" + - "E79" + - "E790" + - "E791" + - "E798" + - "E799" + - "E80" + - "E800" + - "E801" + - "E802" + - "E803" + - "E804" + - "E805" + - "E806" + - "E807" + - "E83" + - "E830" + - "E831" + - "E832" + - "E833" + - "E834" + - "E835" + - "E838" + - "E839" + - "E84" + - "E840" + - "E841" + - "E848" + - "E849" + - "E85" + - "E850" + - "E851" + - "E852" + - "E853" + - "E854" + - "E858" + - "E859" + - "E86" + - "E87" + - "E870" + - "E871" + - "E872" + - "E873" + - "E874" + - "E875" + - "E876" + - "E877" + - "E878" + - "E88" + - "E880" + - "E881" + - "E882" + - "E883" + - "E888" + - "E889" + - "E89" + - "E890" + - "E891" + - "E892" + - "E893" + - "E894" + - "E895" + - "E896" + - "E898" + - "E899" + - "E90" + - name: "J69 Pneumonitis due to solids and liquids" + codings: + - "J691" + - "J698" + - "J690" + - name: "O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium" + codings: + - "O995" + - "O996" + - "O997" + - "O998" + - "O990" + - "O991" + - "O992" + - "O993" + - "O994" + - name: "G62 Other polyneuropathies" + codings: + - "G621" + - "G622" + - "G628" + - "G629" + - "G620" + - name: "O63 Long labour" + codings: + - "O632" + - "O639" + - "O630" + - "O631" + - name: "O68 Labour and delivery complicated by foetal stress [distress]" + codings: + - "O680" + - "O681" + - "O682" + - "O683" + - "O688" + - "O689" + - name: "O69 Labour and delivery complicated by umbilical cord complications" + codings: + - "O699" + - "O690" + - "O691" + - "O692" + - "O693" + - "O694" + - "O695" + - "O698" + - name: "K65 Peritonitis" + codings: + - "K650" + - "K658" + - "K659" + - name: "J18 Pneumonia, organism unspecified" + codings: + - "J180" + - "J181" + - "J182" + - "J188" + - "J189" + - name: "L29 Pruritus" + codings: + - "L290" + - "L291" + - "L292" + - "L293" + - "L298" + - "L299" + - name: "M35 Other systemic involvement of connective tissue" + codings: + - "M350" + - "M351" + - "M352" + - "M353" + - "M354" + - "M355" + - "M356" + - "M357" + - "M358" + - "M359" + - "M3599" + - name: "F10-F19 Mental and behavioural disorders due to psychoactive substance use" + codings: + - "F10" + - "F100" + - "F101" + - "F102" + - "F103" + - "F104" + - "F105" + - "F106" + - "F107" + - "F108" + - "F109" + - "F11" + - "F110" + - "F111" + - "F112" + - "F113" + - "F114" + - "F115" + - "F116" + - "F117" + - "F118" + - "F119" + - "F12" + - "F120" + - "F121" + - "F122" + - "F123" + - "F124" + - "F125" + - "F126" + - "F127" + - "F128" + - "F129" + - "F13" + - "F130" + - "F131" + - "F132" + - "F133" + - "F134" + - "F135" + - "F136" + - "F137" + - "F138" + - "F139" + - "F14" + - "F140" + - "F141" + - "F142" + - "F143" + - "F144" + - "F145" + - "F146" + - "F147" + - "F148" + - "F149" + - "F15" + - "F150" + - "F151" + - "F152" + - "F153" + - "F154" + - "F155" + - "F156" + - "F157" + - "F158" + - "F159" + - "F16" + - "F160" + - "F161" + - "F162" + - "F163" + - "F164" + - "F165" + - "F166" + - "F167" + - "F168" + - "F169" + - "F17" + - "F170" + - "F171" + - "F172" + - "F173" + - "F174" + - "F175" + - "F176" + - "F177" + - "F178" + - "F179" + - "F18" + - "F180" + - "F181" + - "F182" + - "F183" + - "F184" + - "F185" + - "F186" + - "F187" + - "F188" + - "F189" + - "F19" + - "F190" + - "F191" + - "F192" + - "F193" + - "F194" + - "F195" + - "F196" + - "F197" + - "F198" + - "F199" + - name: "K01 Embedded and impacted teeth" + codings: + - "K010" + - "K011" + - name: "K02 Dental caries" + codings: + - "K020" + - "K021" + - "K022" + - "K023" + - "K024" + - "K025" + - "K028" + - "K029" + - name: "K04 Diseases of pulp and periapical tissues" + codings: + - "K040" + - "K041" + - "K042" + - "K043" + - "K044" + - "K045" + - "K046" + - "K047" + - "K048" + - "K049" + - name: "K05 Gingivitis and periodontal diseases" + codings: + - "K050" + - "K051" + - "K052" + - "K0522" + - "K053" + - "K054" + - "K055" + - "K056" + - name: "K07 Dentofacial anomalies [including malocclusion]" + codings: + - "K070" + - "K071" + - "K072" + - "K073" + - "K074" + - "K075" + - "K076" + - "K078" + - "K079" + - name: "K08 Other disorders of teeth and supporting structures" + codings: + - "K080" + - "K081" + - "K082" + - "K083" + - "K088" + - "K089" + - name: "K61 Abscess of anal and rectal regions" + codings: + - "K612" + - "K613" + - "K614" + - "K610" + - "K611" + - name: "I10 Essential (primary) hypertension" + codings: + - "I10" + - name: "I12 Hypertensive renal disease" + codings: + - "I120" + - "I129" + - name: "G60-G64 Polyneuropathies and other disorders of the peripheral nervous system" + codings: + - "G60" + - "G600" + - "G601" + - "G602" + - "G603" + - "G608" + - "G609" + - "G61" + - "G610" + - "G611" + - "G618" + - "G619" + - "G62" + - "G620" + - "G621" + - "G622" + - "G628" + - "G629" + - "G63" + - "G630" + - "G631" + - "G632" + - "G633" + - "G634" + - "G635" + - "G636" + - "G638" + - "G64" + - name: "N75 Diseases of Bartholin's gland" + codings: + - "N750" + - "N751" + - "N758" + - "N759" + - name: "N76 Other inflammation of vagina and vulva" + codings: + - "N760" + - "N761" + - "N762" + - "N763" + - "N764" + - "N765" + - "N766" + - "N768" + - name: "N70 Salpingitis and oophoritis" + codings: + - "N700" + - "N701" + - "N709" + - name: "N72 Inflammatory disease of cervix uteri" + codings: + - "N72" + - name: "N73 Other female pelvic inflammatory diseases" + codings: + - "N730" + - "N731" + - "N732" + - "N733" + - "N734" + - "N735" + - "N736" + - "N738" + - "N739" + - name: "I70-I79 Diseases of arteries, arterioles and capillaries" + codings: + - "I7081" + - "I709" + - "I7090" + - "I7091" + - "I71" + - "I710" + - "I711" + - "I712" + - "I713" + - "I714" + - "I715" + - "I716" + - "I718" + - "I719" + - "I72" + - "I720" + - "I721" + - "I722" + - "I723" + - "I724" + - "I725" + - "I726" + - "I728" + - "I729" + - "I73" + - "I730" + - "I731" + - "I738" + - "I739" + - "I74" + - "I740" + - "I741" + - "I742" + - "I743" + - "I744" + - "I745" + - "I748" + - "I749" + - "I77" + - "I770" + - "I771" + - "I772" + - "I773" + - "I774" + - "I775" + - "I776" + - "I778" + - "I779" + - "I78" + - "I780" + - "I781" + - "I788" + - "I789" + - "I79" + - "I790" + - "I791" + - "I792" + - "I798" + - "I70" + - "I700" + - "I7000" + - "I7001" + - "I701" + - "I7010" + - "I7011" + - "I702" + - "I7020" + - "I7021" + - "I708" + - "I7080" + - name: "K92 Other diseases of digestive system" + codings: + - "K920" + - "K921" + - "K922" + - "K928" + - "K929" + - name: "K91 Postprocedural disorders of digestive system, not elsewhere classified" + codings: + - "K910" + - "K911" + - "K912" + - "K913" + - "K914" + - "K915" + - "K918" + - "K919" + - name: "K90 Intestinal malabsorption" + codings: + - "K900" + - "K901" + - "K902" + - "K903" + - "K904" + - "K908" + - "K909" + - name: "L55-L59 Radiation-related disorders of the skin and subcutaneous tissue" + codings: + - "L598" + - "L599" + - "L55" + - "L550" + - "L551" + - "L552" + - "L558" + - "L559" + - "L56" + - "L560" + - "L561" + - "L562" + - "L563" + - "L564" + - "L568" + - "L569" + - "L57" + - "L570" + - "L571" + - "L572" + - "L573" + - "L574" + - "L575" + - "L578" + - "L579" + - "L58" + - "L580" + - "L581" + - "L589" + - "L59" + - "L590" + - name: "H60-H62 Diseases of external ear" + codings: + - "H60" + - "H600" + - "H601" + - "H602" + - "H603" + - "H604" + - "H605" + - "H608" + - "H609" + - "H61" + - "H610" + - "H611" + - "H612" + - "H613" + - "H618" + - "H619" + - "H62" + - "H620" + - "H621" + - "H622" + - "H623" + - "H624" + - "H628" + - name: "H30-H36 Disorders of choroid and retina" + codings: + - "H30" + - "H300" + - "H301" + - "H302" + - "H308" + - "H309" + - "H31" + - "H310" + - "H311" + - "H312" + - "H313" + - "H314" + - "H318" + - "H319" + - "H32" + - "H320" + - "H328" + - "H33" + - "H330" + - "H331" + - "H332" + - "H333" + - "H334" + - "H335" + - "H34" + - "H340" + - "H341" + - "H342" + - "H348" + - "H349" + - "H35" + - "H350" + - "H351" + - "H352" + - "H353" + - "H354" + - "H355" + - "H356" + - "H357" + - "H358" + - "H359" + - "H36" + - "H360" + - "H368" + - name: "I89 Other non-infective disorders of lymphatic vessels and lymph nodes" + codings: + - "I891" + - "I898" + - "I899" + - "I890" + - name: "K35-K38 Diseases of appendix" + codings: + - "K380" + - "K381" + - "K382" + - "K383" + - "K388" + - "K389" + - "K35" + - "K350" + - "K351" + - "K352" + - "K353" + - "K358" + - "K359" + - "K36" + - "K37" + - "K38" + - name: "I83 Varicose veins of lower extremities" + codings: + - "I830" + - "I831" + - "I832" + - "I839" + - name: "I80 Phlebitis and thrombophlebitis" + codings: + - "I809" + - "I800" + - "I801" + - "I802" + - "I803" + - "I808" + - name: "I20-I25 Ischaemic heart diseases" + codings: + - "I238" + - "I24" + - "I240" + - "I241" + - "I248" + - "I249" + - "I25" + - "I250" + - "I251" + - "I252" + - "I253" + - "I254" + - "I255" + - "I256" + - "I258" + - "I259" + - "I20" + - "I200" + - "I201" + - "I208" + - "I209" + - "I21" + - "I210" + - "I211" + - "I212" + - "I213" + - "I214" + - "I219" + - "I21X" + - "I22" + - "I220" + - "I221" + - "I228" + - "I229" + - "I23" + - "I230" + - "I231" + - "I232" + - "I233" + - "I234" + - "I235" + - "I236" + - name: "I84 Haemorrhoids" + codings: + - "I840" + - "I841" + - "I842" + - "I843" + - "I844" + - "I845" + - "I846" + - "I847" + - "I848" + - "I849" + - name: "I85 Oesophageal varices" + codings: + - "I850" + - "I859" + - name: "M89 Other disorders of bone" + codings: + - "M8947" + - "M8948" + - "M8949" + - "M895" + - "M8950" + - "M8951" + - "M8952" + - "M8953" + - "M8954" + - "M8955" + - "M8956" + - "M8957" + - "M8958" + - "M8959" + - "M896" + - "M8960" + - "M8961" + - "M8962" + - "M8963" + - "M8964" + - "M8965" + - "M8966" + - "M8967" + - "M8968" + - "M8969" + - "M898" + - "M8980" + - "M8981" + - "M8982" + - "M8983" + - "M8984" + - "M8985" + - "M8986" + - "M8987" + - "M8988" + - "M8989" + - "M899" + - "M8990" + - "M8991" + - "M8992" + - "M8993" + - "M8994" + - "M8995" + - "M8996" + - "M8997" + - "M8998" + - "M8999" + - "M890" + - "M8900" + - "M8901" + - "M8902" + - "M8903" + - "M8904" + - "M8905" + - "M8906" + - "M8907" + - "M8908" + - "M8909" + - "M891" + - "M8910" + - "M8911" + - "M8912" + - "M8913" + - "M8914" + - "M8915" + - "M8916" + - "M8917" + - "M8918" + - "M8919" + - "M892" + - "M8920" + - "M8921" + - "M8922" + - "M8923" + - "M8924" + - "M8925" + - "M8926" + - "M8927" + - "M8928" + - "M8929" + - "M893" + - "M8930" + - "M8931" + - "M8932" + - "M8933" + - "M8934" + - "M8935" + - "M8936" + - "M8937" + - "M8938" + - "M8939" + - "M894" + - "M8940" + - "M8941" + - "M8942" + - "M8943" + - "M8944" + - "M8945" + - "M8946" + - name: "M86 Osteomyelitis" + codings: + - "M860" + - "M8600" + - "M8601" + - "M8602" + - "M8603" + - "M8604" + - "M8605" + - "M8606" + - "M8607" + - "M8608" + - "M8609" + - "M861" + - "M8610" + - "M8611" + - "M8612" + - "M8613" + - "M8614" + - "M8615" + - "M8616" + - "M8617" + - "M8618" + - "M8619" + - "M862" + - "M8620" + - "M8621" + - "M8622" + - "M8623" + - "M8624" + - "M8625" + - "M8626" + - "M8627" + - "M8628" + - "M8629" + - "M863" + - "M8630" + - "M8631" + - "M8632" + - "M8633" + - "M8634" + - "M8635" + - "M8636" + - "M8637" + - "M8638" + - "M8639" + - "M864" + - "M8640" + - "M8641" + - "M8642" + - "M8643" + - "M8644" + - "M8645" + - "M8646" + - "M8647" + - "M8648" + - "M8649" + - "M865" + - "M8650" + - "M8651" + - "M8652" + - "M8653" + - "M8654" + - "M8655" + - "M8656" + - "M8657" + - "M8658" + - "M8659" + - "M866" + - "M8660" + - "M8661" + - "M8662" + - "M8663" + - "M8664" + - "M8665" + - "M8666" + - "M8667" + - "M8668" + - "M8669" + - "M868" + - "M8680" + - "M8681" + - "M8682" + - "M8683" + - "M8684" + - "M8685" + - "M8686" + - "M8687" + - "M8688" + - "M8689" + - "M869" + - "M8690" + - "M8691" + - "M8692" + - "M8693" + - "M8694" + - "M8695" + - "M8696" + - "M8697" + - "M8698" + - "M8699" + - name: "M87 Osteonecrosis" + codings: + - "M8722" + - "M8723" + - "M8724" + - "M8725" + - "M8726" + - "M8727" + - "M8728" + - "M8729" + - "M873" + - "M8730" + - "M8731" + - "M8732" + - "M8733" + - "M8734" + - "M8735" + - "M8736" + - "M8737" + - "M8738" + - "M8739" + - "M878" + - "M8780" + - "M8781" + - "M8782" + - "M8783" + - "M8784" + - "M8785" + - "M8786" + - "M8787" + - "M8788" + - "M8789" + - "M879" + - "M8790" + - "M8791" + - "M8792" + - "M8793" + - "M8794" + - "M8795" + - "M8796" + - "M8797" + - "M8798" + - "M8799" + - "M870" + - "M8700" + - "M8701" + - "M8702" + - "M8703" + - "M8704" + - "M8705" + - "M8706" + - "M8707" + - "M8708" + - "M8709" + - "M871" + - "M8710" + - "M8711" + - "M8712" + - "M8713" + - "M8714" + - "M8715" + - "M8716" + - "M8717" + - "M8718" + - "M8719" + - "M872" + - "M8720" + - "M8721" + - name: "M84 Disorders of continuity of bone" + codings: + - "M8442" + - "M8443" + - "M8444" + - "M8445" + - "M8446" + - "M8447" + - "M8448" + - "M8449" + - "M848" + - "M8480" + - "M8481" + - "M8482" + - "M8483" + - "M8484" + - "M8485" + - "M8486" + - "M8487" + - "M8488" + - "M8489" + - "M849" + - "M8490" + - "M8491" + - "M8492" + - "M8493" + - "M8494" + - "M8495" + - "M8496" + - "M8497" + - "M8498" + - "M8499" + - "M840" + - "M8400" + - "M8401" + - "M8402" + - "M8403" + - "M8404" + - "M8405" + - "M8406" + - "M8407" + - "M8408" + - "M8409" + - "M841" + - "M8410" + - "M8411" + - "M8412" + - "M8413" + - "M8414" + - "M8415" + - "M8416" + - "M8417" + - "M8418" + - "M8419" + - "M842" + - "M8420" + - "M8421" + - "M8422" + - "M8423" + - "M8424" + - "M8425" + - "M8426" + - "M8427" + - "M8428" + - "M8429" + - "M843" + - "M8430" + - "M8431" + - "M8432" + - "M8433" + - "M8434" + - "M8435" + - "M8436" + - "M8437" + - "M8438" + - "M8439" + - "M844" + - "M8440" + - "M8441" + - name: "M85 Other disorders of bone density and structure" + codings: + - "M850" + - "M8500" + - "M8501" + - "M8502" + - "M8503" + - "M8504" + - "M8505" + - "M8506" + - "M8507" + - "M8508" + - "M8509" + - "M851" + - "M8510" + - "M8511" + - "M8512" + - "M8513" + - "M8514" + - "M8515" + - "M8516" + - "M8517" + - "M8518" + - "M8519" + - "M852" + - "M8520" + - "M8521" + - "M8522" + - "M8523" + - "M8524" + - "M8525" + - "M8526" + - "M8527" + - "M8528" + - "M8529" + - "M853" + - "M8530" + - "M8531" + - "M8532" + - "M8533" + - "M8534" + - "M8535" + - "M8536" + - "M8537" + - "M8538" + - "M8539" + - "M854" + - "M8540" + - "M8541" + - "M8542" + - "M8543" + - "M8544" + - "M8545" + - "M8546" + - "M8547" + - "M8548" + - "M8549" + - "M855" + - "M8550" + - "M8551" + - "M8552" + - "M8553" + - "M8554" + - "M8555" + - "M8556" + - "M8557" + - "M8558" + - "M8559" + - "M856" + - "M8560" + - "M8561" + - "M8562" + - "M8563" + - "M8564" + - "M8565" + - "M8566" + - "M8567" + - "M8568" + - "M8569" + - "M858" + - "M8580" + - "M8581" + - "M8582" + - "M8583" + - "M8584" + - "M8585" + - "M8586" + - "M8587" + - "M8588" + - "M8589" + - "M859" + - "M8590" + - "M8591" + - "M8592" + - "M8593" + - "M8594" + - "M8595" + - "M8596" + - "M8597" + - "M8598" + - "M8599" + - name: "M80 Osteoporosis with pathological fracture" + codings: + - "M800" + - "M8000" + - "M8001" + - "M8002" + - "M8003" + - "M8004" + - "M8005" + - "M8006" + - "M8007" + - "M8008" + - "M8009" + - "M801" + - "M8010" + - "M8011" + - "M8012" + - "M8013" + - "M8014" + - "M8015" + - "M8016" + - "M8017" + - "M8018" + - "M8019" + - "M802" + - "M8020" + - "M8021" + - "M8022" + - "M8023" + - "M8024" + - "M8025" + - "M8026" + - "M8027" + - "M8028" + - "M8029" + - "M803" + - "M8030" + - "M8031" + - "M8032" + - "M8033" + - "M8034" + - "M8035" + - "M8036" + - "M8037" + - "M8038" + - "M8039" + - "M804" + - "M8040" + - "M8041" + - "M8042" + - "M8043" + - "M8044" + - "M8045" + - "M8046" + - "M8047" + - "M8048" + - "M8049" + - "M805" + - "M8050" + - "M8051" + - "M8052" + - "M8053" + - "M8054" + - "M8055" + - "M8056" + - "M8057" + - "M8058" + - "M8059" + - "M808" + - "M8080" + - "M8081" + - "M8082" + - "M8083" + - "M8084" + - "M8085" + - "M8086" + - "M8087" + - "M8088" + - "M8089" + - "M809" + - "M8090" + - "M8091" + - "M8092" + - "M8093" + - "M8094" + - "M8095" + - "M8096" + - "M8097" + - "M8098" + - "M8099" + - name: "M81 Osteoporosis without pathological fracture" + codings: + - "M810" + - "M8100" + - "M8101" + - "M8102" + - "M8103" + - "M8104" + - "M8105" + - "M8106" + - "M8107" + - "M8108" + - "M8109" + - "M811" + - "M8110" + - "M8111" + - "M8112" + - "M8113" + - "M8114" + - "M8115" + - "M8116" + - "M8117" + - "M8118" + - "M8119" + - "M812" + - "M8120" + - "M8121" + - "M8122" + - "M8123" + - "M8124" + - "M8125" + - "M8126" + - "M8127" + - "M8128" + - "M8129" + - "M813" + - "M8130" + - "M8131" + - "M8132" + - "M8133" + - "M8134" + - "M8135" + - "M8136" + - "M8137" + - "M8138" + - "M8139" + - "M814" + - "M8140" + - "M8141" + - "M8142" + - "M8143" + - "M8144" + - "M8145" + - "M8146" + - "M8147" + - "M8148" + - "M8149" + - "M815" + - "M8150" + - "M8151" + - "M8152" + - "M8153" + - "M8154" + - "M8155" + - "M8156" + - "M8157" + - "M8158" + - "M8159" + - "M816" + - "M8160" + - "M8161" + - "M8162" + - "M8163" + - "M8164" + - "M8165" + - "M8166" + - "M8167" + - "M8168" + - "M8169" + - "M818" + - "M8180" + - "M8181" + - "M8182" + - "M8183" + - "M8184" + - "M8185" + - "M8186" + - "M8187" + - "M8188" + - "M8189" + - "M819" + - "M8190" + - "M8191" + - "M8192" + - "M8193" + - "M8194" + - "M8195" + - "M8196" + - "M8197" + - "M8198" + - "M8199" + - name: "B15-B19 Viral hepatitis" + codings: + - "B15" + - "B150" + - "B159" + - "B16" + - "B160" + - "B161" + - "B162" + - "B169" + - "B17" + - "B170" + - "B171" + - "B172" + - "B178" + - "B179" + - "B18" + - "B180" + - "B181" + - "B182" + - "B188" + - "B189" + - "B19" + - "B190" + - "B199" + - name: "M62 Other disorders of muscle" + codings: + - "M620" + - "M6200" + - "M6201" + - "M6202" + - "M6203" + - "M6204" + - "M6205" + - "M6206" + - "M6207" + - "M6208" + - "M6209" + - "M621" + - "M6210" + - "M6211" + - "M6212" + - "M6213" + - "M6214" + - "M6215" + - "M6216" + - "M6217" + - "M6218" + - "M6219" + - "M622" + - "M6220" + - "M6221" + - "M6222" + - "M6223" + - "M6224" + - "M6225" + - "M6226" + - "M6227" + - "M6228" + - "M6229" + - "M623" + - "M6230" + - "M6231" + - "M6232" + - "M6233" + - "M6234" + - "M6235" + - "M6236" + - "M6237" + - "M6238" + - "M6239" + - "M624" + - "M6240" + - "M6241" + - "M6242" + - "M6243" + - "M6244" + - "M6245" + - "M6246" + - "M6247" + - "M6248" + - "M6249" + - "M625" + - "M6250" + - "M6251" + - "M6252" + - "M6253" + - "M6254" + - "M6255" + - "M6256" + - "M6257" + - "M6258" + - "M6259" + - "M626" + - "M6260" + - "M6261" + - "M6262" + - "M6263" + - "M6264" + - "M6265" + - "M6266" + - "M6267" + - "M6268" + - "M6269" + - "M628" + - "M6280" + - "M6281" + - "M6282" + - "M6283" + - "M6284" + - "M6285" + - "M6286" + - "M6287" + - "M6288" + - "M6289" + - "M629" + - "M6290" + - "M6291" + - "M6292" + - "M6293" + - "M6294" + - "M6295" + - "M6296" + - "M6297" + - "M6298" + - "M6299" + - name: "M65 Synovitis and tenosynovitis" + codings: + - "M6521" + - "M6522" + - "M6523" + - "M6524" + - "M6525" + - "M6526" + - "M6527" + - "M6528" + - "M6529" + - "M653" + - "M6530" + - "M6531" + - "M6532" + - "M6533" + - "M6534" + - "M6535" + - "M6536" + - "M6537" + - "M6538" + - "M6539" + - "M654" + - "M6540" + - "M6541" + - "M6542" + - "M6543" + - "M6544" + - "M6545" + - "M6546" + - "M6547" + - "M6548" + - "M6549" + - "M658" + - "M6580" + - "M6581" + - "M6582" + - "M6583" + - "M6584" + - "M6585" + - "M6586" + - "M6587" + - "M6588" + - "M6589" + - "M659" + - "M6590" + - "M6591" + - "M6592" + - "M6593" + - "M6594" + - "M6595" + - "M6596" + - "M6597" + - "M6598" + - "M6599" + - "M650" + - "M6500" + - "M6501" + - "M6502" + - "M6503" + - "M6504" + - "M6505" + - "M6506" + - "M6507" + - "M6508" + - "M6509" + - "M651" + - "M6510" + - "M6511" + - "M6512" + - "M6513" + - "M6514" + - "M6515" + - "M6516" + - "M6517" + - "M6518" + - "M6519" + - "M652" + - "M6520" + - name: "M66 Spontaneous rupture of synovium and tendon" + codings: + - "M660" + - "M6600" + - "M6601" + - "M6602" + - "M6603" + - "M6604" + - "M6605" + - "M6606" + - "M6607" + - "M6608" + - "M6609" + - "M661" + - "M6610" + - "M6611" + - "M6612" + - "M6613" + - "M6614" + - "M6615" + - "M6616" + - "M6617" + - "M6618" + - "M6619" + - "M662" + - "M6620" + - "M6621" + - "M6622" + - "M6623" + - "M6624" + - "M6625" + - "M6626" + - "M6627" + - "M6628" + - "M6629" + - "M663" + - "M6630" + - "M6631" + - "M6632" + - "M6633" + - "M6634" + - "M6635" + - "M6636" + - "M6637" + - "M6638" + - "M6639" + - "M664" + - "M6640" + - "M6641" + - "M6642" + - "M6643" + - "M6644" + - "M6645" + - "M6646" + - "M6647" + - "M6648" + - "M6649" + - "M665" + - "M6650" + - "M6651" + - "M6652" + - "M6653" + - "M6654" + - "M6655" + - "M6656" + - "M6657" + - "M6658" + - "M6659" + - name: "M67 Other disorders of synovium and tendon" + codings: + - "M6747" + - "M6749" + - "M678" + - "M679" + - "M6796" + - "M670" + - "M671" + - "M672" + - "M673" + - "M674" + - "M6743" + - "M6745" + - name: "H80-H83 Diseases of inner ear" + codings: + - "H83" + - "H830" + - "H831" + - "H832" + - "H833" + - "H838" + - "H839" + - "H80" + - "H800" + - "H801" + - "H802" + - "H808" + - "H809" + - "H81" + - "H810" + - "H811" + - "H812" + - "H813" + - "H814" + - "H818" + - "H819" + - "H82" + - name: "M50-M54 Other dorsopathies" + codings: + - "M50" + - "M500" + - "M501" + - "M502" + - "M503" + - "M508" + - "M509" + - "M51" + - "M510" + - "M511" + - "M5116" + - "M5119" + - "M512" + - "M513" + - "M5137" + - "M514" + - "M518" + - "M519" + - "M53" + - "M530" + - "M5300" + - "M5301" + - "M5302" + - "M5303" + - "M5304" + - "M5305" + - "M5306" + - "M5307" + - "M5308" + - "M5309" + - "M531" + - "M5310" + - "M5311" + - "M5312" + - "M5313" + - "M5314" + - "M5315" + - "M5316" + - "M5317" + - "M5318" + - "M5319" + - "M532" + - "M5320" + - "M5321" + - "M5322" + - "M5323" + - "M5324" + - "M5325" + - "M5326" + - "M5327" + - "M5328" + - "M5329" + - "M533" + - "M5330" + - "M5331" + - "M5332" + - "M5333" + - "M5334" + - "M5335" + - "M5336" + - "M5337" + - "M5338" + - "M5339" + - "M538" + - "M5380" + - "M5381" + - "M5382" + - "M5383" + - "M5384" + - "M5385" + - "M5386" + - "M5387" + - "M5388" + - "M5389" + - "M539" + - "M5390" + - "M5391" + - "M5392" + - "M5393" + - "M5394" + - "M5395" + - "M5396" + - "M5397" + - "M5398" + - "M5399" + - "M54" + - "M540" + - "M5400" + - "M5401" + - "M5402" + - "M5403" + - "M5404" + - "M5405" + - "M5406" + - "M5407" + - "M5408" + - "M5409" + - "M541" + - "M5410" + - "M5411" + - "M5412" + - "M5413" + - "M5414" + - "M5415" + - "M5416" + - "M5417" + - "M5418" + - "M5419" + - "M542" + - "M5420" + - "M5421" + - "M5422" + - "M5423" + - "M5424" + - "M5425" + - "M5426" + - "M5427" + - "M5428" + - "M5429" + - "M543" + - "M5430" + - "M5431" + - "M5432" + - "M5433" + - "M5434" + - "M5435" + - "M5436" + - "M5437" + - "M5438" + - "M5439" + - "M544" + - "M5440" + - "M5441" + - "M5442" + - "M5443" + - "M5444" + - "M5445" + - "M5446" + - "M5447" + - "M5448" + - "M5449" + - "M545" + - "M5450" + - "M5451" + - "M5452" + - "M5453" + - "M5454" + - "M5455" + - "M5456" + - "M5457" + - "M5458" + - "M5459" + - "M546" + - "M5460" + - "M5461" + - "M5462" + - "M5463" + - "M5464" + - "M5465" + - "M5466" + - "M5467" + - "M5468" + - "M5469" + - "M548" + - "M5480" + - "M5481" + - "M5482" + - "M5483" + - "M5484" + - "M5485" + - "M5486" + - "M5487" + - "M5488" + - "M5489" + - "M549" + - "M5490" + - "M5491" + - "M5492" + - "M5493" + - "M5494" + - "M5495" + - "M5496" + - "M5497" + - "M5498" + - "M5499" + - name: "N70-N77 Inflammatory diseases of female pelvic organs" + codings: + - "N744" + - "N748" + - "N75" + - "N750" + - "N751" + - "N758" + - "N759" + - "N76" + - "N760" + - "N761" + - "N762" + - "N763" + - "N764" + - "N765" + - "N766" + - "N768" + - "N77" + - "N770" + - "N771" + - "N778" + - "N70" + - "N700" + - "N701" + - "N709" + - "N71" + - "N710" + - "N711" + - "N719" + - "N72" + - "N73" + - "N730" + - "N731" + - "N732" + - "N733" + - "N734" + - "N735" + - "N736" + - "N738" + - "N739" + - "N74" + - "N740" + - "N741" + - "N742" + - "N743" + - name: "H43 Disorders of vitreous body" + codings: + - "H433" + - "H438" + - "H439" + - "H430" + - "H431" + - "H432" + - name: "H40 Glaucoma" + codings: + - "H400" + - "H401" + - "H402" + - "H403" + - "H404" + - "H405" + - "H406" + - "H408" + - "H409" + - name: "H00-H06 Disorders of eyelid, lacrimal system and orbit" + codings: + - "H028" + - "H029" + - "H03" + - "H030" + - "H031" + - "H038" + - "H04" + - "H040" + - "H041" + - "H042" + - "H043" + - "H044" + - "H045" + - "H046" + - "H048" + - "H049" + - "H05" + - "H050" + - "H051" + - "H052" + - "H053" + - "H054" + - "H055" + - "H058" + - "H059" + - "H06" + - "H060" + - "H061" + - "H062" + - "H063" + - "H00" + - "H000" + - "H001" + - "H01" + - "H010" + - "H011" + - "H018" + - "H019" + - "H02" + - "H020" + - "H021" + - "H022" + - "H023" + - "H024" + - "H025" + - "H026" + - "H027" + - fields: + - "20002" + phenotypes: + - name: "oesophageal disorder" + codings: + - "1134" + - "1139" + - "1140" + - "1141" + - "1138" + - "1474" + - name: "bacterial infection" + codings: + - "1442" + - "1440" + - "1574" + - "1572" + - "1677" + - "1678" + - "1566" + - name: "psychological/psychiatric problem" + codings: + - "1243" + - "1286" + - "1287" + - "1288" + - "1289" + - "1290" + - "1291" + - "1614" + - "1615" + - "1408" + - "1409" + - "1410" + - "1616" + - "1469" + - "1470" + - "1531" + - name: "heart valve problem/heart murmur" + codings: + - "1078" + - "1488" + - "1489" + - "1490" + - "1584" + - "1585" + - "1586" + - "1587" + - name: "other fractures" + codings: + - "1644" + - "1645" + - "1646" + - name: "glaucoma" + codings: + - "1277" + - name: "gastric/stomach ulcers" + codings: + - "1142" + - name: "mumps / epidemic parotitis" + codings: + - "1569" + - name: "other renal/kidney problem" + codings: + - "1405" + - "1427" + - "1607" + - "1608" + - "1609" + - "1519" + - "1520" + - name: "hypothyroidism/myxoedema" + codings: + - "1226" + - name: "epilepsy" + codings: + - "1264" + - name: "hiatus hernia" + codings: + - "1474" + - name: "eczema/dermatitis" + codings: + - "1452" + - name: "other neurological problem" + codings: + - "1434" + - "1659" + - "1436" + - "1437" + - "1526" + - "1683" + - "1525" + - name: "gastritis/gastric erosions" + codings: + - "1143" + - name: "kidney stone/ureter stone/bladder stone" + codings: + - "1197" + - name: "carpal tunnel syndrome" + codings: + - "1541" + - name: "breast disease (not cancer)" + codings: + - "1364" + - "1560" + - "1366" + - "1367" + - "1666" + - name: "gynaecological disorder (not cancer)" + codings: + - "1348" + - "1350" + - "1402" + - "1681" + - "1554" + - "1662" + - "1663" + - "1664" + - "1665" + - "1403" + - "1555" + - "1551" + - "1552" + - "1553" + - "1351" + - "1352" + - "1556" + - "1557" + - "1353" + - "1349" + - name: "depression" + codings: + - "1286" + - "1531" + - name: "pleurisy" + codings: + - "1125" + - name: "gestational hypertension/pre-eclampsia" + codings: + - "1073" + - name: "cerebrovascular disease" + codings: + - "1425" + - "1081" + - "1082" + - "1083" + - "1086" + - "1583" + - "1491" + - name: "disc problem" + codings: + - "1532" + - "1533" + - "1312" + - name: "mania/bipolar disorder/manic depression" + codings: + - "1291" + - name: "angina" + codings: + - "1074" + - name: "measles / morbillivirus" + codings: + - "1568" + - name: "urinary tract infection/kidney infection" + codings: + - "1196" + - "1514" + - "1515" + - name: "other respiratory problems" + codings: + - "1117" + - "1125" + - "1123" + - "1124" + - "1497" + - "1126" + - "1595" + - "1596" + - name: "appendicitis" + codings: + - "1502" + - name: "allergy/hypersensitivity/anaphylaxis" + codings: + - "1374" + - "1668" + - "1669" + - "1670" + - "1671" + - "1385" + - "1386" + - "1387" + - "1562" + - "1563" + - name: "other abdominal problem" + codings: + - "1137" + - "1509" + - "1400" + - "1511" + - "1512" + - "1513" + - "1605" + - "1606" + - "1190" + - "1191" + - "1510" + - name: "allergy or anaphylactic reaction to food" + codings: + - "1385" + - name: "heart arrhythmia" + codings: + - "1077" + - "1483" + - "1484" + - "1485" + - "1486" + - "1487" + - "1471" + - name: "sarcoidosis" + codings: + - "1371" + - name: "ankylosing spondylitis" + codings: + - "1313" + - name: "viral infection" + codings: + - "1439" + - "1568" + - "1570" + - "1674" + - "1571" + - "1573" + - "1575" + - "1567" + - "1569" + - name: "vasculitis" + codings: + - "1372" + - "1376" + - "1377" + - "1378" + - "1379" + - "1380" + - name: "cervical spondylosis" + codings: + - "1478" + - name: "soft tissue inflammation" + codings: + - "1618" + - "1619" + - "1620" + - "1621" + - "1622" + - "1623" + - "1624" + - name: "essential hypertension" + codings: + - "1072" + - name: "fracture head & neck" + codings: + - "1626" + - "1627" + - "1628" + - "1629" + - "1630" + - name: "anal problem" + codings: + - "1503" + - "1505" + - "1504" + - name: "colitis/not crohns or ulcerative colitis" + codings: + - "1459" + - name: "ent disorder/not cancer" + codings: + - "1418" + - "1419" + - "1420" + - "1421" + - "1598" + - "1500" + - "1499" + - "1597" + - "1413" + - "1414" + - "1415" + - "1416" + - "1417" + - name: "sciatica" + codings: + - "1476" + - name: "duodenal ulcer" + codings: + - "1457" + - name: "joint disorder" + codings: + - "1295" + - "1537" + - "1538" + - "1477" + - "1464" + - "1465" + - "1466" + - "1467" + - name: "bone disorder" + codings: + - "1293" + - "1308" + - "1309" + - "1310" + - "1617" + - name: "haematology" + codings: + - "1446" + - "1447" + - "1448" + - "1449" + - "1450" + - "1451" + - "1546" + - "1339" + - "1340" + - "1438" + - "1327" + - "1328" + - "1658" + - "1331" + - "1332" + - "1330" + - "1445" + - name: "rheumatic fever" + codings: + - "1479" + - name: "liver/biliary/pancreas problem" + codings: + - "1136" + - "1163" + - "1164" + - "1507" + - "1508" + - "1506" + - "1604" + - "1578" + - "1579" + - "1580" + - "1165" + - "1582" + - "1581" + - "1475" + - "1155" + - "1156" + - "1157" + - "1158" + - "1159" + - "1160" + - "1161" + - "1162" + - name: "diabetic eye disease" + codings: + - "1276" + - name: "tuberculosis (tb)" + codings: + - "1440" + - name: "eye/eyelid problem" + codings: + - "1242" + - "1527" + - "1282" + - "1528" + - "1613" + - "1435" + - "1274" + - "1275" + - "1276" + - "1277" + - "1529" + - "1530" + - "1281" + - "1279" + - "1278" + - name: "peripheral vascular disease" + codings: + - "1067" + - "1087" + - "1088" + - "1592" + - "1492" + - "1591" + - name: "pancreatic disease" + codings: + - "1164" + - "1165" + - name: "bowel problem" + codings: + - "1505" + - "1599" + - "1600" + - "1601" + - "1602" + - "1603" + - "1456" + - "1457" + - "1458" + - "1459" + - "1460" + - "1461" + - "1462" + - "1463" + - "1154" + - "1502" + - "1503" + - "1504" + - name: "hayfever/allergic rhinitis" + codings: + - "1387" + - name: "anaemia" + codings: + - "1446" + - "1330" + - "1331" + - "1332" + - name: "irritable bowel syndrome" + codings: + - "1154" + - name: "obstetric problem" + codings: + - "1558" + - "1559" + - name: "back pain" + codings: + - "1534" + - name: "transient ischaemic attack (tia)" + codings: + - "1082" + - name: "psoriasis" + codings: + - "1453" + - name: "blistering/desquamating skin disorder" + codings: + - "1454" + - "1344" + - "1345" + - name: "abdominal hernia" + codings: + - "1511" + - "1513" + - "1605" + - "1606" + - "1512" + - name: "neck problem/injury" + codings: + - "1545" + - "1478" + - name: "deep venous thrombosis (dvt)" + codings: + - "1094" + - name: "other urological problem (male)" + codings: + - "1396" + - "1516" + - "1517" + - "1404" + - "1679" + - "1207" + - "1210" + - "1214" + - "1518" + - name: "stomach disorder" + codings: + - "1135" + - "1143" + - "1142" + - "1501" + - name: "osteoarthritis" + codings: + - "1465" + - name: "hepatitis" + codings: + - "1155" + - "1578" + - "1579" + - "1580" + - "1581" + - "1582" + - "1156" + - "1157" + - name: "hypertension" + codings: + - "1065" + - "1072" + - "1073" + - name: "muscle or soft tissue injuries" + codings: + - "1406" + - name: "other joint disorder" + codings: + - "1467" + - "1537" + - name: "malabsorption/coeliac disease" + codings: + - "1456" + - name: "stroke" + codings: + - "1081" + - "1583" + - "1491" + - "1086" + - name: "dermatology" + codings: + - "1345" + - "1660" + - "1452" + - "1453" + - "1454" + - "1455" + - "1548" + - "1549" + - "1550" + - "1661" + - "1667" + - "1680" + - "1344" + - "1625" + - name: "head injury" + codings: + - "1266" + - name: "heart attack/myocardial infarction" + codings: + - "1075" + - name: "chronic obstructive airways disease/copd" + codings: + - "1112" + - name: "diverticular disease/diverticulitis" + codings: + - "1458" + - name: "peripheral nerve disorder" + codings: + - "1254" + - "1468" + - "1255" + - "1256" + - "1257" + - name: "prostate problem (not cancer)" + codings: + - "1207" + - "1396" + - "1516" + - "1517" + - name: "sleep apnoea" + codings: + - "1123" + - name: "helicobacter pylori" + codings: + - "1442" + - name: "allergy or anaphylactic reaction to drug" + codings: + - "1386" + - name: "osteomyelitis" + codings: + - "1308" + - name: "pulmonary embolism +/- dvt" + codings: + - "1093" + - name: "retinal problem" + codings: + - "1275" + - "1281" + - "1282" + - "1527" + - "1528" + - name: "heart/cardiac problem" + codings: + - "1066" + - "1479" + - "1483" + - "1484" + - "1485" + - "1486" + - "1487" + - "1488" + - "1489" + - "1490" + - "1426" + - "1074" + - "1075" + - "1076" + - "1077" + - "1078" + - "1079" + - "1080" + - "1584" + - "1585" + - "1586" + - "1587" + - "1588" + - "1589" + - "1590" + - "1471" + - name: "fracture pelvis & lower limb" + codings: + - "1654" + - "1655" + - "1656" + - "1647" + - "1648" + - "1649" + - "1650" + - "1651" + - "1652" + - "1653" + - name: "fracture upper limb & shoulder" + codings: + - "1631" + - "1632" + - "1633" + - "1634" + - "1635" + - "1636" + - "1637" + - "1638" + - "1639" + - "1640" + - name: "hyperthyroidism/thyrotoxicosis" + codings: + - "1225" + - name: "benign breast lump" + codings: + - "1666" + - name: "varicose veins" + codings: + - "1494" + - name: "back problem" + codings: + - "1294" + - "1476" + - "1311" + - "1312" + - "1313" + - "1532" + - "1533" + - "1534" + - "1535" + - "1536" + - name: "dyspepsia / indigestion" + codings: + - "1510" + - name: "bladder problem (not cancer)" + codings: + - "1201" + - "1202" + - name: "renal/kidney failure" + codings: + - "1192" + - "1193" + - "1194" + - name: "urinary frequency / incontinence" + codings: + - "1202" + - name: "spine arthritis/spondylitis" + codings: + - "1311" + - name: "rectal or colon adenoma/polyps" + codings: + - "1460" + - name: "substance abuse/dependency" + codings: + - "1408" + - "1409" + - "1410" + - name: "ovarian problem" + codings: + - "1551" + - "1350" + - "1681" + - "1349" + - name: "bronchiectasis" + codings: + - "1114" + - name: "bronchitis" + codings: + - "1412" + - name: "eye trauma" + codings: + - "1279" + - name: "migraine" + codings: + - "1265" + - name: "high cholesterol" + codings: + - "1473" + - name: "osteoporosis" + codings: + - "1309" + - name: "fracture" + codings: + - "1626" + - "1627" + - "1628" + - "1629" + - "1630" + - "1631" + - "1632" + - "1633" + - "1634" + - "1635" + - "1636" + - "1637" + - "1638" + - "1639" + - "1640" + - "1644" + - "1645" + - "1646" + - "1647" + - "1648" + - "1649" + - "1650" + - "1651" + - "1652" + - "1653" + - "1654" + - "1655" + - "1656" + - name: "ear/vestibular disorder" + codings: + - "1415" + - "1597" + - "1420" + - "1500" + - "1499" + - "1421" + - name: "oesophagitis/barretts oesophagus" + codings: + - "1139" + - name: "tropical & travel-related infections" + codings: + - "1441" + - "1443" + - "1576" + - "1577" + - "1675" + - "1676" + - name: "connective tissue disorder" + codings: + - "1373" + - "1376" + - "1372" + - "1481" + - "1480" + - "1377" + - "1378" + - "1379" + - "1380" + - "1381" + - "1382" + - "1383" + - "1384" + - "1561" + - name: "gall bladder disease" + codings: + - "1161" + - "1163" + - "1162" + - name: "thyroid problem (not cancer)" + codings: + - "1224" + - "1225" + - "1226" + - "1228" + - "1428" + - "1610" + - "1522" + - name: "fibromyalgia" + codings: + - "1542" + - name: "neurology" + codings: + - "1254" + - "1255" + - "1256" + - "1257" + - "1258" + - "1259" + - "1260" + - "1261" + - "1262" + - "1263" + - "1264" + - "1265" + - "1397" + - "1523" + - "1524" + - "1525" + - "1526" + - "1659" + - "1433" + - "1434" + - "1436" + - "1437" + - "1468" + - "1683" + - "1244" + - "1245" + - "1246" + - "1247" + - "1248" + - "1249" + - "1250" + - "1251" + - "1252" + - name: "diabetes" + codings: + - "1220" + - "1223" + - "1521" + - "1221" + - "1222" + - name: "respiratory infection" + codings: + - "1594" + - "1411" + - "1498" + - "1398" + - name: "cervical problem" + codings: + - "1553" + - "1662" + - "1554" + - "1555" + - "1663" + - name: "venous thromboembolic disease" + codings: + - "1068" + - "1094" + - "1093" + - name: "clotting disorder/excessive bleeding" + codings: + - "1445" + - "1546" + - "1327" + - "1328" + - name: "rosacea" + codings: + - "1660" + - name: "miscarriage" + codings: + - "1559" + - name: "varicella zoster virus" + codings: + - "1674" + - "1571" + - "1573" + - name: "emphysema/chronic bronchitis" + codings: + - "1113" + - "1412" + - "1472" + - "1496" + - name: "asthma" + codings: + - "1111" + - name: "cataract" + codings: + - "1278" + - name: "breast cysts" + codings: + - "1367" + - name: "muscle/soft tissue problem" + codings: + - "1297" + - "1540" + - "1541" + - "1542" + - "1544" + - "1619" + - "1322" + - "1618" + - "1406" + - "1620" + - "1621" + - "1622" + - "1623" + - "1624" + - name: "uterine problem" + codings: + - "1552" + - "1351" + - "1352" + - "1353" + - "1402" + - name: "rheumatoid arthritis" + codings: + - "1464" + - name: "spinal injury" + codings: + - "1267" + - name: "throat or larynx disorder" + codings: + - "1414" + - "1418" + - "1419" + - "1598" + - name: "peritonitis" + codings: + - "1190" + - name: "osteopenia" + codings: + - "1617" + - name: "nasal/sinus disorder" + codings: + - "1413" + - "1416" + - "1417" + - name: "inflammatory bowel disease" + codings: + - "1461" + - "1462" + - "1463" + - name: "disorder or pituitary gland" + codings: + - "1237" + - "1429" + - "1430" + - "1431" + - "1238" + - name: "dry eyes" + codings: + - "1529" + - name: "other venous/lymphatic disease" + codings: + - "1493" + - "1593" + - "1494" + - "1495" + - name: "infection of nervous system" + codings: + - "1244" + - "1246" + - "1247" + - "1248" + - "1245" + - name: "cranial nerve problem/palsy" + codings: + - "1249" + - "1523" + - "1250" + - name: "arthritis (nos)" + codings: + - "1538" + - name: "chronic fatigue syndrome" + codings: + - "1482" + - name: "pneumonia" + codings: + - "1398" + - name: "psoriatic arthropathy" + codings: + - "1477" + - name: "anxiety/panic attacks" + codings: + - "1287" + - name: "chronic/degenerative neurological problem" + codings: + - "1258" + - "1397" + - "1259" + - "1260" + - "1261" + - "1262" + - "1263" + - name: "type 2 diabetes" + codings: + - "1223" + - name: "gastro-oesophageal reflux (gord) / gastric reflux" + codings: + - "1138" + - name: "pneumothorax" + codings: + - "1497" + - "1126" + - name: "neurological injury/trauma" + codings: + - "1240" + - "1266" + - "1267" + - "1394" + - name: "gout" + codings: + - "1466" + - name: "testicular problems (not cancer)" + codings: + - "1214" + - name: "nervous breakdown" + codings: + - "1288" + - name: "menorrhagia (unknown cause)" + codings: + - "1556" + - fields: + - "40006" + phenotypes: + - name: "C43 Malignant melanoma of skin" + codings: + - "C430" + - "C431" + - "C432" + - "C433" + - "C434" + - "C435" + - "C436" + - "C437" + - "C438" + - "C439" + - name: "D37-D48 Neoplasms of uncertain or unknown behaviour" + codings: + - "D419" + - "D42" + - "D420" + - "D421" + - "D429" + - "D43" + - "D430" + - "D431" + - "D432" + - "D433" + - "D434" + - "D437" + - "D439" + - "D44" + - "D440" + - "D441" + - "D442" + - "D443" + - "D444" + - "D445" + - "D446" + - "D447" + - "D448" + - "D449" + - "D45" + - "D46" + - "D460" + - "D461" + - "D462" + - "D463" + - "D464" + - "D465" + - "D466" + - "D467" + - "D469" + - "D47" + - "D470" + - "D471" + - "D472" + - "D473" + - "D474" + - "D475" + - "D477" + - "D479" + - "D48" + - "D480" + - "D481" + - "D482" + - "D483" + - "D484" + - "D485" + - "D486" + - "D487" + - "D489" + - "D37" + - "D370" + - "D371" + - "D372" + - "D373" + - "D374" + - "D375" + - "D376" + - "D377" + - "D379" + - "D38" + - "D380" + - "D381" + - "D382" + - "D383" + - "D384" + - "D385" + - "D386" + - "D39" + - "D390" + - "D391" + - "D392" + - "D397" + - "D399" + - "D40" + - "D400" + - "D401" + - "D407" + - "D409" + - "D41" + - "D410" + - "D411" + - "D412" + - "D413" + - "D414" + - "D417" + - name: "D41 Neoplasm of uncertain or unknown behaviour of urinary organs" + codings: + - "D419" + - "D410" + - "D411" + - "D412" + - "D413" + - "D414" + - "D417" + - name: "C34 Malignant neoplasm of bronchus and lung" + codings: + - "C341" + - "C342" + - "C343" + - "C348" + - "C349" + - "C340" + - name: "D06 Carcinoma in situ of cervix uteri" + codings: + - "D069" + - "D060" + - "D061" + - "D067" + - name: "D05 Carcinoma in situ of breast" + codings: + - "D050" + - "D051" + - "D057" + - "D059" + - name: "D04 Carcinoma in situ of skin" + codings: + - "D040" + - "D041" + - "D042" + - "D043" + - "D044" + - "D045" + - "D046" + - "D047" + - "D048" + - "D049" + - name: "D03 Melanoma in situ" + codings: + - "D036" + - "D037" + - "D038" + - "D039" + - "D030" + - "D031" + - "D032" + - "D033" + - "D034" + - "D035" + - name: "C50-C50 Malignant neoplasm of breast" + codings: + - "C50" + - "C500" + - "C501" + - "C502" + - "C503" + - "C504" + - "C505" + - "C506" + - "C508" + - "C509" + - name: "C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue" + codings: + - "C81" + - "C810" + - "C811" + - "C812" + - "C813" + - "C814" + - "C817" + - "C819" + - "C82" + - "C820" + - "C821" + - "C822" + - "C823" + - "C824" + - "C825" + - "C826" + - "C827" + - "C829" + - "C83" + - "C830" + - "C831" + - "C832" + - "C833" + - "C834" + - "C835" + - "C836" + - "C837" + - "C838" + - "C839" + - "C84" + - "C840" + - "C841" + - "C842" + - "C843" + - "C844" + - "C845" + - "C846" + - "C847" + - "C848" + - "C849" + - "C85" + - "C850" + - "C851" + - "C852" + - "C857" + - "C859" + - "C86" + - "C860" + - "C861" + - "C862" + - "C863" + - "C864" + - "C865" + - "C866" + - "C88" + - "C880" + - "C881" + - "C882" + - "C883" + - "C884" + - "C887" + - "C889" + - "C90" + - "C900" + - "C901" + - "C902" + - "C903" + - "C91" + - "C910" + - "C911" + - "C912" + - "C913" + - "C914" + - "C915" + - "C916" + - "C917" + - "C918" + - "C919" + - "C92" + - "C920" + - "C921" + - "C922" + - "C923" + - "C924" + - "C925" + - "C926" + - "C927" + - "C928" + - "C929" + - "C93" + - "C930" + - "C931" + - "C932" + - "C933" + - "C937" + - "C939" + - "C94" + - "C940" + - "C941" + - "C942" + - "C943" + - "C944" + - "C945" + - "C946" + - "C947" + - "C95" + - "C950" + - "C951" + - "C952" + - "C957" + - "C959" + - "C96" + - "C960" + - "C961" + - "C962" + - "C963" + - "C964" + - "C965" + - "C966" + - "C967" + - "C968" + - "C969" + - name: "C20 Malignant neoplasm of rectum" + codings: + - "C20" + - name: "C43-C44 Melanoma and other malignant neoplasms of skin" + codings: + - "C43" + - "C430" + - "C431" + - "C432" + - "C433" + - "C434" + - "C435" + - "C436" + - "C437" + - "C438" + - "C439" + - "C44" + - "C440" + - "C441" + - "C442" + - "C443" + - "C444" + - "C445" + - "C446" + - "C447" + - "C448" + - "C449" + - name: "C44 Other malignant neoplasms of skin" + codings: + - "C440" + - "C441" + - "C442" + - "C443" + - "C444" + - "C445" + - "C446" + - "C447" + - "C448" + - "C449" + - name: "C64-C68 Malignant neoplasms of urinary tract" + codings: + - "C66" + - "C67" + - "C670" + - "C671" + - "C672" + - "C673" + - "C674" + - "C675" + - "C676" + - "C677" + - "C678" + - "C679" + - "C68" + - "C680" + - "C681" + - "C688" + - "C689" + - "C64" + - "C65" + - name: "D00-D09 In situ neoplasms" + codings: + - "D036" + - "D037" + - "D038" + - "D039" + - "D04" + - "D040" + - "D041" + - "D042" + - "D043" + - "D044" + - "D045" + - "D046" + - "D047" + - "D048" + - "D049" + - "D05" + - "D050" + - "D051" + - "D057" + - "D059" + - "D06" + - "D060" + - "D061" + - "D067" + - "D069" + - "D07" + - "D070" + - "D071" + - "D072" + - "D073" + - "D074" + - "D075" + - "D076" + - "D09" + - "D090" + - "D091" + - "D092" + - "D093" + - "D097" + - "D099" + - "D00" + - "D000" + - "D001" + - "D002" + - "D01" + - "D010" + - "D011" + - "D012" + - "D013" + - "D014" + - "D015" + - "D017" + - "D019" + - "D02" + - "D020" + - "D021" + - "D022" + - "D023" + - "D024" + - "D03" + - "D030" + - "D031" + - "D032" + - "D033" + - "D034" + - "D035" + - name: "C15-C26 Malignant neoplasms of digestive organs" + codings: + - "C15" + - "C150" + - "C151" + - "C152" + - "C153" + - "C154" + - "C155" + - "C158" + - "C159" + - "C16" + - "C160" + - "C161" + - "C162" + - "C163" + - "C164" + - "C165" + - "C166" + - "C168" + - "C169" + - "C17" + - "C170" + - "C171" + - "C172" + - "C173" + - "C178" + - "C179" + - "C18" + - "C180" + - "C181" + - "C182" + - "C183" + - "C184" + - "C185" + - "C186" + - "C187" + - "C188" + - "C189" + - "C19" + - "C20" + - "C21" + - "C210" + - "C211" + - "C212" + - "C218" + - "C22" + - "C220" + - "C221" + - "C222" + - "C223" + - "C224" + - "C227" + - "C229" + - "C23" + - "C24" + - "C240" + - "C241" + - "C248" + - "C249" + - "C25" + - "C250" + - "C251" + - "C252" + - "C253" + - "C254" + - "C257" + - "C258" + - "C259" + - "C26" + - "C260" + - "C261" + - "C268" + - "C269" + - name: "C67 Malignant neoplasm of bladder" + codings: + - "C670" + - "C671" + - "C672" + - "C673" + - "C674" + - "C675" + - "C676" + - "C677" + - "C678" + - "C679" + - name: "C64 Malignant neoplasm of kidney, except renal pelvis" + codings: + - "C64" + - name: "C61 Malignant neoplasm of prostate" + codings: + - "C61" + - name: "C18 Malignant neoplasm of colon" + codings: + - "C181" + - "C182" + - "C183" + - "C184" + - "C185" + - "C186" + - "C187" + - "C188" + - "C189" + - "C180" + - name: "C83 Diffuse non-Hodgkin's lymphoma" + codings: + - "C832" + - "C833" + - "C834" + - "C835" + - "C836" + - "C837" + - "C838" + - "C839" + - "C830" + - "C831" + - name: "C30-C39 Malignant neoplasms of respiratory and intrathoracic organs" + codings: + - "C30" + - "C300" + - "C301" + - "C31" + - "C310" + - "C311" + - "C312" + - "C313" + - "C318" + - "C319" + - "C32" + - "C320" + - "C321" + - "C322" + - "C323" + - "C328" + - "C329" + - "C33" + - "C34" + - "C340" + - "C341" + - "C342" + - "C343" + - "C348" + - "C349" + - "C37" + - "C38" + - "C380" + - "C381" + - "C382" + - "C383" + - "C384" + - "C388" + - "C39" + - "C390" + - "C398" + - "C399" + - name: "C56 Malignant neoplasm of ovary" + codings: + - "C56" + - name: "C54 Malignant neoplasm of corpus uteri" + codings: + - "C540" + - "C541" + - "C542" + - "C543" + - "C548" + - "C549" + - name: "C50 Malignant neoplasm of breast" + codings: + - "C500" + - "C501" + - "C502" + - "C503" + - "C504" + - "C505" + - "C506" + - "C508" + - "C509" + - name: "C00-C14 Malignant neoplasms of lip, oral cavity and pharynx" + codings: + - "C14" + - "C140" + - "C142" + - "C148" + - "C00" + - "C000" + - "C001" + - "C002" + - "C003" + - "C004" + - "C005" + - "C006" + - "C008" + - "C009" + - "C01" + - "C02" + - "C020" + - "C021" + - "C022" + - "C023" + - "C024" + - "C028" + - "C029" + - "C03" + - "C030" + - "C031" + - "C039" + - "C04" + - "C040" + - "C041" + - "C048" + - "C049" + - "C05" + - "C050" + - "C051" + - "C052" + - "C058" + - "C059" + - "C06" + - "C060" + - "C061" + - "C062" + - "C068" + - "C069" + - "C07" + - "C08" + - "C080" + - "C081" + - "C088" + - "C089" + - "C09" + - "C090" + - "C091" + - "C098" + - "C099" + - "C10" + - "C100" + - "C101" + - "C102" + - "C103" + - "C104" + - "C108" + - "C109" + - "C11" + - "C110" + - "C111" + - "C112" + - "C113" + - "C118" + - "C119" + - "C12" + - "C13" + - "C130" + - "C131" + - "C132" + - "C138" + - "C139" + - name: "C51-C58 Malignant neoplasms of female genital organs" + codings: + - "C51" + - "C510" + - "C511" + - "C512" + - "C518" + - "C519" + - "C52" + - "C53" + - "C530" + - "C531" + - "C538" + - "C539" + - "C54" + - "C540" + - "C541" + - "C542" + - "C543" + - "C548" + - "C549" + - "C55" + - "C56" + - "C57" + - "C570" + - "C571" + - "C572" + - "C573" + - "C574" + - "C577" + - "C578" + - "C579" + - "C58" + - name: "C60-C63 Malignant neoplasms of male genital organs" + codings: + - "C60" + - "C600" + - "C601" + - "C602" + - "C608" + - "C609" + - "C61" + - "C62" + - "C620" + - "C621" + - "C629" + - "C63" + - "C630" + - "C631" + - "C632" + - "C637" + - "C638" + - "C639" + - name: "D10-D36 Benign neoplasms" + codings: + - "D10" + - "D100" + - "D101" + - "D102" + - "D103" + - "D104" + - "D105" + - "D106" + - "D107" + - "D109" + - "D11" + - "D110" + - "D117" + - "D119" + - "D12" + - "D120" + - "D121" + - "D122" + - "D123" + - "D124" + - "D125" + - "D126" + - "D127" + - "D128" + - "D129" + - "D13" + - "D130" + - "D131" + - "D132" + - "D133" + - "D134" + - "D135" + - "D136" + - "D137" + - "D139" + - "D14" + - "D140" + - "D141" + - "D142" + - "D143" + - "D144" + - "D15" + - "D150" + - "D151" + - "D152" + - "D157" + - "D159" + - "D16" + - "D160" + - "D161" + - "D162" + - "D163" + - "D164" + - "D165" + - "D166" + - "D167" + - "D168" + - "D169" + - "D17" + - "D170" + - "D171" + - "D172" + - "D173" + - "D174" + - "D175" + - "D176" + - "D177" + - "D179" + - "D18" + - "D180" + - "D181" + - "D19" + - "D190" + - "D191" + - "D197" + - "D199" + - "D20" + - "D200" + - "D201" + - "D21" + - "D210" + - "D211" + - "D212" + - "D213" + - "D214" + - "D215" + - "D216" + - "D219" + - "D22" + - "D220" + - "D221" + - "D222" + - "D223" + - "D224" + - "D225" + - "D226" + - "D227" + - "D229" + - "D23" + - "D230" + - "D231" + - "D232" + - "D233" + - "D234" + - "D235" + - "D236" + - "D237" + - "D239" + - "D24" + - "D25" + - "D250" + - "D251" + - "D252" + - "D259" + - "D26" + - "D260" + - "D261" + - "D267" + - "D269" + - "D27" + - "D28" + - "D280" + - "D281" + - "D282" + - "D287" + - "D289" + - "D29" + - "D290" + - "D291" + - "D292" + - "D293" + - "D294" + - "D297" + - "D299" + - "D30" + - "D300" + - "D301" + - "D302" + - "D303" + - "D304" + - "D307" + - "D309" + - "D31" + - "D310" + - "D311" + - "D312" + - "D313" + - "D314" + - "D315" + - "D316" + - "D319" + - "D32" + - "D320" + - "D321" + - "D329" + - "D33" + - "D330" + - "D331" + - "D332" + - "D333" + - "D334" + - "D337" + - "D339" + - "D34" + - "D35" + - "D350" + - "D351" + - "D352" + - "D353" + - "D354" + - "D355" + - "D356" + - "D357" + - "D358" + - "D359" + - "D36" + - "D360" + - "D361" + - "D367" + - "D369" + - fields: + - "1408" + phenotypes: + - name: "Cheese intake" + - fields: + - "1777" + phenotypes: + - name: "Part of a multiple birth" + - fields: + - "1727" + phenotypes: + - name: "Ease of skin tanning" + - fields: + - "1548" + phenotypes: + - name: "Variation in diet" + - fields: + - "728" + phenotypes: + - name: "Number of vehicles in household" + - fields: + - "1717" + phenotypes: + - name: "Skin colour" + - fields: + - "1389" + phenotypes: + - name: "Pork intake" + - fields: + - "1478" + phenotypes: + - name: "Salt added to food" + - fields: + - "1518" + phenotypes: + - name: "Hot drink temperature" + - fields: + - "1558" + phenotypes: + - name: "Alcohol intake frequency." + - fields: + - "20117" + phenotypes: + - name: "Alcohol drinker status" + - fields: + - "1349" + phenotypes: + - name: "Processed meat intake" + - fields: + - "1359" + phenotypes: + - name: "Poultry intake" + - fields: + - "1369" + phenotypes: + - name: "Beef intake" + - fields: + - "1379" + phenotypes: + - name: "Lamb/mutton intake" + - fields: + - "1329" + phenotypes: + - name: "Oily fish intake" + - fields: + - "1339" + phenotypes: + - name: "Non-oily fish intake" + - fields: + - "20116" + phenotypes: + - name: "Smoking status" + - fields: + - "1239" + phenotypes: + - name: "Current tobacco smoking" + - fields: + - "1687" + phenotypes: + - name: "Comparative body size at age 10" + - fields: + - "1697" + phenotypes: + - name: "Comparative height size at age 10" + - fields: + - "1707" + phenotypes: + - name: "Handedness (chirality/laterality)" + - fields: + - "30260" + phenotypes: + - name: "Mean reticulocyte volume" + - fields: + - "30280" + phenotypes: + - name: "Immature reticulocyte fraction" + - fields: + - "30240" + phenotypes: + - name: "Reticulocyte percentage" + - fields: + - "30250" + phenotypes: + - name: "Reticulocyte count" + - fields: + - "30300" + phenotypes: + - name: "High light scatter reticulocyte count" + - fields: + - "30270" + phenotypes: + - name: "Mean sphered cell volume" + - fields: + - "30290" + phenotypes: + - name: "High light scatter reticulocyte percentage" + - fields: + - "30230" + phenotypes: + - name: "Nucleated red blood cell percentage" + - fields: + - "30170" + phenotypes: + - name: "Nucleated red blood cell count" + - fields: + - "30120" + phenotypes: + - name: "Lymphocyte count" + - fields: + - "30130" + phenotypes: + - name: "Monocyte count" + - fields: + - "30140" + phenotypes: + - name: "Neutrophill count" + - fields: + - "30150" + phenotypes: + - name: "Eosinophill count" + - fields: + - "30160" + phenotypes: + - name: "Basophill count" + - fields: + - "30180" + phenotypes: + - name: "Lymphocyte percentage" + - fields: + - "30190" + phenotypes: + - name: "Monocyte percentage" + - fields: + - "30200" + phenotypes: + - name: "Neutrophill percentage" + - fields: + - "30210" + phenotypes: + - name: "Eosinophill percentage" + - fields: + - "30220" + phenotypes: + - name: "Basophill percentage" + - fields: + - "30100" + phenotypes: + - name: "Mean platelet (thrombocyte) volume" + - fields: + - "30110" + phenotypes: + - name: "Platelet distribution width" + - fields: + - "30060" + phenotypes: + - name: "Mean corpuscular haemoglobin concentration" + - fields: + - "30090" + phenotypes: + - name: "Platelet crit" + - fields: + - "30000" + phenotypes: + - name: "White blood cell (leukocyte) count" + - fields: + - "30050" + phenotypes: + - name: "Mean corpuscular haemoglobin" + - fields: + - "30080" + phenotypes: + - name: "Platelet count" + - fields: + - "30040" + phenotypes: + - name: "Mean corpuscular volume" + - fields: + - "30070" + phenotypes: + - name: "Red blood cell (erythrocyte) distribution width" + - fields: + - "30010" + phenotypes: + - name: "Red blood cell (erythrocyte) count" + - fields: + - "30020" + phenotypes: + - name: "Haemoglobin concentration" + - fields: + - "30030" + phenotypes: + - name: "Haematocrit percentage" + - fields: + - "23100" + phenotypes: + - name: "Whole body fat mass" + - fields: + - "23130" + phenotypes: + - name: "Trunk predicted mass" + - fields: + - "23129" + phenotypes: + - name: "Trunk fat-free mass" + - fields: + - "23128" + phenotypes: + - name: "Trunk fat mass" + - fields: + - "23127" + phenotypes: + - name: "Trunk fat percentage" + - fields: + - "23099" + phenotypes: + - name: "Body fat percentage" + - fields: + - "23126" + phenotypes: + - name: "Arm predicted mass (left)" + - fields: + - "23125" + phenotypes: + - name: "Arm fat-free mass (left)" + - fields: + - "23124" + phenotypes: + - name: "Arm fat mass (left)" + - fields: + - "23123" + phenotypes: + - name: "Arm fat percentage (left)" + - fields: + - "23122" + phenotypes: + - name: "Arm predicted mass (right)" + - fields: + - "23121" + phenotypes: + - name: "Arm fat-free mass (right)" + - fields: + - "23120" + phenotypes: + - name: "Arm fat mass (right)" + - fields: + - "23119" + phenotypes: + - name: "Arm fat percentage (right)" + - fields: + - "23118" + phenotypes: + - name: "Leg predicted mass (left)" + - fields: + - "23117" + phenotypes: + - name: "Leg fat-free mass (left)" + - fields: + - "23116" + phenotypes: + - name: "Leg fat mass (left)" + - fields: + - "23115" + phenotypes: + - name: "Leg fat percentage (left)" + - fields: + - "23109" + phenotypes: + - name: "Impedance of arm (right)" + - fields: + - "23114" + phenotypes: + - name: "Leg predicted mass (right)" + - fields: + - "23113" + phenotypes: + - name: "Leg fat-free mass (right)" + - fields: + - "23106" + phenotypes: + - name: "Impedance of whole body" + - fields: + - "23101" + phenotypes: + - name: "Whole body fat-free mass" + - fields: + - "23112" + phenotypes: + - name: "Leg fat mass (right)" + - fields: + - "23110" + phenotypes: + - name: "Impedance of arm (left)" + - fields: + - "23111" + phenotypes: + - name: "Leg fat percentage (right)" + - fields: + - "23108" + phenotypes: + - name: "Impedance of leg (left)" + - fields: + - "23107" + phenotypes: + - name: "Impedance of leg (right)" + - fields: + - "23105" + phenotypes: + - name: "Basal metabolic rate" + - fields: + - "23102" + phenotypes: + - name: "Whole body water mass" + - fields: + - "20015" + phenotypes: + - name: "Sitting height" + - fields: + - "21001" + phenotypes: + - name: "Body mass index (BMI)" + - fields: + - "21002" + phenotypes: + - name: "Weight" + - fields: + - "50" + phenotypes: + - name: "Standing height" + - fields: + - "49" + phenotypes: + - name: "Hip circumference" + - fields: + - "48" + phenotypes: + - name: "Waist circumference" + - fields: + - "1319" + phenotypes: + - name: "Dried fruit intake" + - fields: + - "1498" + phenotypes: + - name: "Coffee intake" + - fields: + - "1528" + phenotypes: + - name: "Water intake" + - fields: + - "2277" + phenotypes: + - name: "Frequency of solarium/sunlamp use" + - fields: + - "1299" + phenotypes: + - name: "Salad / raw vegetable intake" + - fields: + - "1458" + phenotypes: + - name: "Cereal intake" + - fields: + - "1309" + phenotypes: + - name: "Fresh fruit intake" + - fields: + - "1488" + phenotypes: + - name: "Tea intake" + - fields: + - "1289" + phenotypes: + - name: "Cooked vegetable intake" + - fields: + - "1438" + phenotypes: + - name: "Bread intake" + - fields: + - "1873" + phenotypes: + - name: "Number of full brothers" + - fields: + - "1883" + phenotypes: + - name: "Number of full sisters" + - fields: + - "709" + phenotypes: + - name: "Number in household" + - fields: + - "46" + phenotypes: + - name: "Hand grip strength (left)" + - fields: + - "47" + phenotypes: + - name: "Hand grip strength (right)" + - fields: + - "134" + phenotypes: + - name: "Number of self-reported cancers" + - fields: + - "135" + phenotypes: + - name: "Number of self-reported non-cancer illnesses" + - fields: + - "136" + phenotypes: + - name: "Number of operations, self-reported" + - fields: + - "137" + phenotypes: + - name: "Number of treatments/medications taken" + - fields: + - "1160" + phenotypes: + - name: "Sleep duration" + - fields: + - "20023" + phenotypes: + - name: "Mean time to correctly identify matches" + - fields: + - "3079" + phenotypes: + - name: "Pace-maker" + - fields: + - "21003" + phenotypes: + - name: "Age-Assessment" + - fields: + - "22001" + phenotypes: + - name: "Genetic-Sex" + +subset: + - fields: + - "21000" + phenotypes: + - name: "White" + codings: + - "1001" + - "1002" + - "1003" + - "1" \ No newline at end of file diff --git a/modules/extract_traits.nf b/modules/extract_traits.nf new file mode 100644 index 0000000..242156a --- /dev/null +++ b/modules/extract_traits.nf @@ -0,0 +1,55 @@ +process UKBFieldsList { + label 'ukb_image' + + input: + path ukb_config + + output: + path "fields_list.txt" + + script: + ukb_config = ukb_config.getName() != 'NO_UKB_TRAIT_CONFIG' ? "--conf $ukb_config" : '' + """ + TEMPD=\$(mktemp -d) + JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/UKBMain.jl --startup-file=no /UKBMain.jl/scripts/build_fields_list.jl $ukb_config + """ +} + +process UKBConv { + label 'ukb_image' + + input: + path fields_list + path encrypted_dataset + path encoding_file + + output: + path "ukb_dataset.csv" + + script: + "ukbconv $encrypted_dataset csv -i$fields_list -e$encoding_file -oukb_dataset" +} + +process TraitsFromUKB { + publishDir "$params.OUTDIR/traits", mode: 'symlink' + label 'ukb_image' + label "bigmem" + label "multithreaded" + + input: + path dataset + path ukbconfig + path withdrawal_list + + output: + path 'traits.csv' + + script: + ukbconfig = ukbconfig.getName() != 'NO_UKB_TRAIT_CONFIG' ? "--conf $ukbconfig" : '' + withdrawal_list = withdrawal_list.getName() != 'NO_WITHDRAWAL_LIST' ? "--withdrawal-list $withdrawal_list" : '' + """ + TEMPD=\$(mktemp -d) + JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/UKBMain.jl --startup-file=no --threads $task.cpus /UKBMain.jl/scripts/process_main_dataset.jl \ + $dataset $ukbconfig $withdrawal_list + """ +} \ No newline at end of file diff --git a/modules/ldblocks.nf b/modules/ldblocks.nf new file mode 100644 index 0000000..ee66dc1 --- /dev/null +++ b/modules/ldblocks.nf @@ -0,0 +1,72 @@ +include { longest_prefix } from './utils.nf' + +process pull_ld { + label 'qctool_image' + + input: + tuple val(RSID), val(CHR), val(POS), path(BGEN_FILES) + + output: + tuple val(RSID), val(CHR), val(POS), path("*.sqlite") + + script: + PREFIX = longest_prefix(BGEN_FILES) + """ + if [[ "${params.COHORT}" == "UKBB" ]]; then + CHR_FORMAT=\$(echo ${CHR} | xargs printf "%02d" ) + elif [[ "${params.COHORT}" == "GENOMICC" ]]; then + CHR_FORMAT=\$(echo chr${CHR} ) + fi + + BGEN_FILE="${PREFIX}${CHR}.bgen" + SAMPLE_FILE="${PREFIX}${CHR}.sample" + + # Define lower and upper bounds to scan for LD + LOWER=\$((${POS} - 10000000)) + UPPER=\$((${POS} + 10000000)) + + # Account for the possibility that the scan range becomes negative. + if [ \$LOWER -lt 0 ] + then + LOWER="0" + fi + + if [ \$UPPER -lt 0 ] + then + UPPER="0" + fi + + OUTNAME=\$( echo ${RSID} | sed 's/:/_/g' ) + + # Use bgenix to create a new .bgen file with the info for just the SNP of interest + index file + bgenix -g \$BGEN_FILE -incl-rsids ${RSID} > "\$OUTNAME.bgen" + bgenix -g "\$OUTNAME.bgen" -index + + bgenix -g \$BGEN_FILE -incl-range "\$CHR_FORMAT:\$LOWER-\$UPPER" | qctool -g - -filetype bgen \ + -s \$SAMPLE_FILE -compute-ld-with "\$OUTNAME.bgen" \$SAMPLE_FILE -old "sqlite://\$OUTNAME.sqlite:LD" \ + -min-r2 0.05 + """ + +} + +process compile_ld_information { + label 'r_python_image' + publishDir("$params.OUTDIR/ld_blocks/", mode: "copy", pattern: "*LD_block*") + + input: + path sqlite_files + path csv + path script + + output: + path "LD_for_PCA.csv", emit: ld_pca + path "*_with_LD_blocks.csv" + path "LD_block_length_histogram.png" + + script: + """ + python ${script} --input ${csv} + """ + +} + diff --git a/modules/utils.nf b/modules/utils.nf new file mode 100644 index 0000000..0eb502c --- /dev/null +++ b/modules/utils.nf @@ -0,0 +1,27 @@ +def longest_prefix(files){ + // Only one file, strangely it is not passed as a list + if (files instanceof Collection == false) { + return files.getName() + } + // More than one file + def index = 0 + while(true){ + def current_prefix = files[0].getName()[0..index] + for (file in files){ + if(file.getName()[0..index] != current_prefix){ + return current_prefix[0..-2] + } + } + index++ + } +} + +def filepath_matches_chr_prefix(fp, chr_prefix){ + def fp_string = fp.normalize().toString() + return fp_string.contains(chr_prefix.normalize().toString() + ".") +} + +def leave_chr_out(chr_prefix, bed_files){ + def bed_files_not_matching_chr_prefix = bed_files.findAll{ fp -> !filepath_matches_chr_prefix(fp, chr_prefix) } + return [chr_prefix, bed_files_not_matching_chr_prefix] +} \ No newline at end of file diff --git a/subworkflows/confounders.nf b/subworkflows/confounders.nf new file mode 100644 index 0000000..f250a7d --- /dev/null +++ b/subworkflows/confounders.nf @@ -0,0 +1,26 @@ +include { filterBED; thinByLD; mergeBEDS; SampleQCFilter; FlashPCA; ScreePlot } from '../modules/confounders.nf' +include { leave_chr_out } from '../modules/utils.nf' + +workflow IIDGenotypes{ + take: + flashpca_excl_reg + ld_blocks + bed_files + qc_file + traits + + main: + bed_files_tuple = bed_files + .combine(qc_file) + .combine(ld_blocks) + .combine(traits) + filtered_bedfiles = filterBED(bed_files_tuple) + ld_pruned = thinByLD(filtered_bedfiles.combine(flashpca_excl_reg)) + bedfiles_to_be_merged = ld_pruned.collect() + .map{it -> ["all_genotypes", it]} + mergeBEDS(bedfiles_to_be_merged) + SampleQCFilter(mergeBEDS.out.collect()) + + emit: + SampleQCFilter.out +} diff --git a/subworkflows/extract_traits.nf b/subworkflows/extract_traits.nf new file mode 100644 index 0000000..56775b2 --- /dev/null +++ b/subworkflows/extract_traits.nf @@ -0,0 +1,31 @@ +include { UKBConv; TraitsFromUKB; UKBFieldsList } from '../modules/extract_traits.nf' + +workflow ExtractTraits { + take: + traits_dataset + ukb_config + ukb_withdrawal_list + ukb_encoding_file + + main: + if (params.COHORT == "UKB") { + if (ukb_encoding_file != "NO_UKB_ENCODING_FILE") { + UKBFieldsList(ukb_config) + decrypted_dataset = UKBConv( + UKBFieldsList.out, + traits_dataset, + Channel.value(file("${ukb_encoding_file}", checkIfExists: true)) + ) + } + else { + decrypted_dataset = traits_dataset + } + extracted_traits = TraitsFromUKB(decrypted_dataset, ukb_config, ukb_withdrawal_list) + } + else { + extracted_traits = traits_dataset + } + + emit: + extracted_traits +} \ No newline at end of file diff --git a/subworkflows/ldblocks.nf b/subworkflows/ldblocks.nf new file mode 100644 index 0000000..58b7292 --- /dev/null +++ b/subworkflows/ldblocks.nf @@ -0,0 +1,37 @@ +include { pull_ld; compile_ld_information } from '../modules/ldblocks.nf' + +workflow ImportSNPs { + take: + bgen_files + main: + Channel + .fromPath(params.INPUT_SNPS, checkIfExists: true) + .splitCsv(header:true) + .map { + row -> tuple(row.RSID, row.CHR, row.POS) + } + .combine(bgen_files) + .set { snps_bgen_ch } + + emit: + snps_bgen_ch +} + +workflow ComputeLD { + take: + snps_bgen + + main: + ld_ch = pull_ld(snps_bgen) + // filter for just sqlite files and collect + ld_ch.map{ snp, chr, pos, sqlite_files -> sqlite_files } + .collect() + .set { sqlite_ch } + + // compile LD_block information + csv_ch = Channel.fromPath(params.INPUT_SNPS, checkIfExists: true) + script_ch = Channel.fromPath("$projectDir/py/convert_sqlite.py") + qtls_ch = compile_ld_information(sqlite_ch, csv_ch, script_ch) + emit: + ld_blocks = qtls_ch.ld_pca +} \ No newline at end of file diff --git a/test/bed/ukb_chr1.bed b/test/bed/ukb_chr1.bed new file mode 100644 index 0000000..be218a2 --- /dev/null +++ b/test/bed/ukb_chr1.bed @@ -0,0 +1,81 @@ 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z3%?@{xZ;B%LXjt+O#{{uuI2WRv$29kN-nRUT}C2BYsmv;%J3<-Zv`4fV{oxv**0)ffRVC5hxM)oXh+UTi~L}yRRd;fs*-T0gYn7rZma)Ao}K95eb^#=|KJF1LckaP+u(44$JhlRwlQ%S+tbXVd+o%^ToWQ$4DL{sxxp=AdYXou1XHnG*4Ij24` zcHA`tGEoWBg^BN`t?F{5Tw>%K=o+cE0e65B<(A?(x0i`4*L_MLlkiJrYFnA#}VZ2fp$SCnDlFU2*QtDg5znv1qx zAS&d-4|8YM Date: Tue, 1 Oct 2024 11:23:19 +0100 Subject: [PATCH 09/33] add missing containers & rename --- conf/local_container.config | 7 +++++-- 1 file changed, 5 insertions(+), 2 deletions(-) diff --git a/conf/local_container.config b/conf/local_container.config index df41369..4496a81 100644 --- a/conf/local_container.config +++ b/conf/local_container.config @@ -1,11 +1,14 @@ process { - withLabel: flashpca_image { + withLabel: ukb_image { + container = "/path/to/ukb_image" + } + withLabel: pca_image { container = "/path/to/flashpca_image" } withLabel: tl_core_image { container = "/path/to/tl_core_image" } - withLabel: bgen_python_image { + withLabel: r_python_image { container = "/path/to/bgen_python_image" } withLabel: qctool_image { From de9ad31bf208a88fa06ad41c3a774dd1a3ac75d3 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Tue, 1 Oct 2024 12:14:50 +0100 Subject: [PATCH 10/33] change UKBB cohort name to UKB --- modules/ldblocks.nf | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/modules/ldblocks.nf b/modules/ldblocks.nf index ee66dc1..03c865d 100644 --- a/modules/ldblocks.nf +++ b/modules/ldblocks.nf @@ -12,7 +12,7 @@ process pull_ld { script: PREFIX = longest_prefix(BGEN_FILES) """ - if [[ "${params.COHORT}" == "UKBB" ]]; then + if [[ "${params.COHORT}" == "UKB" ]]; then CHR_FORMAT=\$(echo ${CHR} | xargs printf "%02d" ) elif [[ "${params.COHORT}" == "GENOMICC" ]]; then CHR_FORMAT=\$(echo chr${CHR} ) From aeac47b45fe6e251bd4067840d913bd140b20cb3 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Tue, 1 Oct 2024 12:23:25 +0100 Subject: [PATCH 11/33] update default UKB_CONFIG specification --- modules/extract_traits.nf | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) diff --git a/modules/extract_traits.nf b/modules/extract_traits.nf index 242156a..e241013 100644 --- a/modules/extract_traits.nf +++ b/modules/extract_traits.nf @@ -8,7 +8,7 @@ process UKBFieldsList { path "fields_list.txt" script: - ukb_config = ukb_config.getName() != 'NO_UKB_TRAIT_CONFIG' ? "--conf $ukb_config" : '' + ukb_config = ukb_config.getName() != 'NO_UKB_CONFIG' ? "--conf $ukb_config" : '' """ TEMPD=\$(mktemp -d) JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/UKBMain.jl --startup-file=no /UKBMain.jl/scripts/build_fields_list.jl $ukb_config @@ -45,7 +45,7 @@ process TraitsFromUKB { path 'traits.csv' script: - ukbconfig = ukbconfig.getName() != 'NO_UKB_TRAIT_CONFIG' ? "--conf $ukbconfig" : '' + ukbconfig = ukbconfig.getName() != 'NO_UKB_CONFIG' ? "--conf $ukbconfig" : '' withdrawal_list = withdrawal_list.getName() != 'NO_WITHDRAWAL_LIST' ? "--withdrawal-list $withdrawal_list" : '' """ TEMPD=\$(mktemp -d) From 632d0c565f2ae118f73b16ac30c6310a889e1ee9 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Wed, 2 Oct 2024 08:52:57 +0100 Subject: [PATCH 12/33] update to most recent resource specifications --- conf/base.config | 8 ++++---- 1 file changed, 4 insertions(+), 4 deletions(-) diff --git a/conf/base.config b/conf/base.config index 67c9b35..1d37a02 100644 --- a/conf/base.config +++ b/conf/base.config @@ -1,17 +1,17 @@ process { memory = { 8.GB * task.attempt } - time = { 48.hour * task.attempt } + time = { 48.hour } cpus = 1 withLabel: multithreaded { memory = { 8.GB * task.attempt } - time = { 48.hour * task.attempt } + time = { 48.hour } cpus = 2 } withLabel: bigmem { - memory = { 16.GB * task.attempt } - time = { 48.hour * task.attempt } + memory = { 32.GB * task.attempt } + time = { 48.hour } cpus = 1 } } \ No newline at end of file From a6717cc1d655479c2514c49dd2d8ff8b05eb8439 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Wed, 2 Oct 2024 10:14:19 +0100 Subject: [PATCH 13/33] add exit status 135 & revert back to old clusterOptions --- conf/eddie.config | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) diff --git a/conf/eddie.config b/conf/eddie.config index 0ea579a..8aad65b 100644 --- a/conf/eddie.config +++ b/conf/eddie.config @@ -6,13 +6,13 @@ executor { } process { - clusterOptions = { task.memory ? "-l rl9=false,h_vmem=${task.memory.bytes/task.cpus}" : "-l rl9=false" } + clusterOptions = { task.memory ? "-l h_vmem=${task.memory.bytes/task.cpus}" : null } stageInMode = 'symlink' scratch = 'false' penv = { task.cpus > 1 ? "sharedmem" : null } // common SGE error statuses - errorStrategy = {task.exitStatus in [143,137,104,134,139,140] ? 'retry' : 'finish'} + errorStrategy = {task.exitStatus in [143,137,104,134,135,139,140] ? 'retry' : 'finish'} maxErrors = '-1' maxRetries = 3 From cf703a4ff4ab68bf4f3453e535363eec302606e6 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Wed, 2 Oct 2024 13:06:12 +0100 Subject: [PATCH 14/33] fix bug where task couldn't re-submit on retries --- modules/confounders.nf | 10 +++++----- modules/extract_traits.nf | 14 +++++++------- 2 files changed, 12 insertions(+), 12 deletions(-) diff --git a/modules/confounders.nf b/modules/confounders.nf index 3d7ce82..fe300e6 100644 --- a/modules/confounders.nf +++ b/modules/confounders.nf @@ -13,15 +13,15 @@ process filterBED { script: input_prefix = bedfiles[0].toString().minus('.bed') - qc_file = qcfile.getName() != 'NO_QC_FILE' ? "--qc-file ${qcfile}" : '' - ld_blocks = ld_blocks.getName() != 'NO_LD_BLOCKS' ? "--ld-blocks-file ${ld_blocks}" : '' + qc_file_flag = qcfile.getName() != 'NO_QC_FILE' ? "--qc-file ${qcfile}" : '' + ld_blocks_flag = ld_blocks.getName() != 'NO_LD_BLOCKS' ? "--ld-blocks-file ${ld_blocks}" : '' """ TEMPD=\$(mktemp -d) JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/TargeneCore.jl --startup-file=no /TargeneCore.jl/targenecore.jl \ filter-chromosome ${input_prefix} filtered.${input_prefix} ${traits} \ - ${qc_file} \ + ${qc_file_flag} \ --maf-threshold=${params.MAF_THRESHOLD} \ - ${ld_blocks} + ${ld_blocks_flag} """ } @@ -116,7 +116,7 @@ process ScreePlot { #!/usr/bin/env Rscript library(ggplot2) - pve <- read.table("$pve") + pve <- read.table("${pve}") pve[['PC']] <- 1:nrow(pve) colnames(pve)[1] <- "pve" diff --git a/modules/extract_traits.nf b/modules/extract_traits.nf index e241013..ec6d445 100644 --- a/modules/extract_traits.nf +++ b/modules/extract_traits.nf @@ -8,10 +8,10 @@ process UKBFieldsList { path "fields_list.txt" script: - ukb_config = ukb_config.getName() != 'NO_UKB_CONFIG' ? "--conf $ukb_config" : '' + ukb_config_flag = ukb_config.getName() != 'NO_UKB_CONFIG' ? "--conf $ukb_config" : '' """ TEMPD=\$(mktemp -d) - JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/UKBMain.jl --startup-file=no /UKBMain.jl/scripts/build_fields_list.jl $ukb_config + JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/UKBMain.jl --startup-file=no /UKBMain.jl/scripts/build_fields_list.jl ${ukb_config_flag} """ } @@ -27,7 +27,7 @@ process UKBConv { path "ukb_dataset.csv" script: - "ukbconv $encrypted_dataset csv -i$fields_list -e$encoding_file -oukb_dataset" + "ukbconv ${encrypted_dataset} csv -i${fields_list} -e${encoding_file} -oukb_dataset" } process TraitsFromUKB { @@ -45,11 +45,11 @@ process TraitsFromUKB { path 'traits.csv' script: - ukbconfig = ukbconfig.getName() != 'NO_UKB_CONFIG' ? "--conf $ukbconfig" : '' - withdrawal_list = withdrawal_list.getName() != 'NO_WITHDRAWAL_LIST' ? "--withdrawal-list $withdrawal_list" : '' + ukbconfig_flag = ukbconfig.getName() != 'NO_UKB_CONFIG' ? "--conf ${ukbconfig}" : '' + withdrawal_list_flag = withdrawal_list.getName() != 'NO_WITHDRAWAL_LIST' ? "--withdrawal-list ${withdrawal_list}" : '' """ TEMPD=\$(mktemp -d) - JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/UKBMain.jl --startup-file=no --threads $task.cpus /UKBMain.jl/scripts/process_main_dataset.jl \ - $dataset $ukbconfig $withdrawal_list + JULIA_DEPOT_PATH=\$TEMPD:/opt julia --project=/UKBMain.jl --startup-file=no --threads ${task.cpus} /UKBMain.jl/scripts/process_main_dataset.jl \ + ${dataset} ${ukbconfig_flag} ${withdrawal_list_flag} """ } \ No newline at end of file From 173ceaf66221b4f8979e6fb2721e2dd799e4b106 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 10:26:54 +0100 Subject: [PATCH 15/33] add old cluster options back in --- conf/eddie.config | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/conf/eddie.config b/conf/eddie.config index 8aad65b..86eb55b 100644 --- a/conf/eddie.config +++ b/conf/eddie.config @@ -6,7 +6,7 @@ executor { } process { - clusterOptions = { task.memory ? "-l h_vmem=${task.memory.bytes/task.cpus}" : null } + clusterOptions = { task.memory ? "-l rl9=false,h_vmem=${task.memory.bytes/task.cpus}" : "-l rl9=false" } stageInMode = 'symlink' scratch = 'false' penv = { task.cpus > 1 ? "sharedmem" : null } From 25107d70727ddd091240e2bae880fd619075c855 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 11:26:01 +0100 Subject: [PATCH 16/33] add run_type default --- main.nf | 1 + 1 file changed, 1 insertion(+) diff --git a/main.nf b/main.nf index 35a6f94..651b851 100644 --- a/main.nf +++ b/main.nf @@ -6,6 +6,7 @@ params.TRAITS_DATASET = "You need to provide a Traits dataset." params.UKB_ENCODING_FILE = "NO_UKB_ENCODING_FILE" params.MAF_THRESHOLD = 0.01 params.COHORT = "UKB" +params.RUN_TYPE = "DISCOVERY" params.UKB_CONFIG = "${projectDir}/assets/ukbconfig.yaml" params.UKB_WITHDRAWAL_LIST = "${projectDir}/assets/NO_WITHDRAWAL_LIST" params.OUTDIR = "${launchDir}/results" From 762dc543601a28cc7bae5e0780e3a055535959c6 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 11:26:24 +0100 Subject: [PATCH 17/33] update CHR_FORMAT for ld block removal range --- modules/ldblocks.nf | 8 ++++++-- 1 file changed, 6 insertions(+), 2 deletions(-) diff --git a/modules/ldblocks.nf b/modules/ldblocks.nf index 03c865d..d597bf3 100644 --- a/modules/ldblocks.nf +++ b/modules/ldblocks.nf @@ -13,9 +13,13 @@ process pull_ld { PREFIX = longest_prefix(BGEN_FILES) """ if [[ "${params.COHORT}" == "UKB" ]]; then - CHR_FORMAT=\$(echo ${CHR} | xargs printf "%02d" ) + if [[ "${params.RUN_TYPE}" == "TEST" ]]; then + CHR_FORMAT=\$( echo ${CHR} ) + else + CHR_FORMAT=\$( echo ${CHR} | xargs printf "%02d" ) + fi elif [[ "${params.COHORT}" == "GENOMICC" ]]; then - CHR_FORMAT=\$(echo chr${CHR} ) + CHR_FORMAT=\$( echo chr${CHR} ) fi BGEN_FILE="${PREFIX}${CHR}.bgen" From c11d95bb46ca2cc06896dc6299bf2b84cb6ca1cd Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 11:26:46 +0100 Subject: [PATCH 18/33] fix file configuration --- test/bgen/ukb_chr1.sample | 6404 ++++++++++++++++++------------------- test/bgen/ukb_chr2.sample | 6404 ++++++++++++++++++------------------- test/bgen/ukb_chr3.sample | 6404 ++++++++++++++++++------------------- 3 files changed, 9606 insertions(+), 9606 deletions(-) diff --git a/test/bgen/ukb_chr1.sample b/test/bgen/ukb_chr1.sample index bf69d4b..752c794 100644 --- a/test/bgen/ukb_chr1.sample +++ b/test/bgen/ukb_chr1.sample @@ -1,3204 +1,3204 @@ ID_1 ID_2 missing sex 0 0 0 D -0 HG00096 0 NA -0 HG00097 0 NA -0 HG00099 0 NA -0 HG00100 0 NA -0 HG00101 0 NA -0 HG00102 0 NA -0 HG00103 0 NA -0 HG00105 0 NA -0 HG00106 0 NA -0 HG00107 0 NA -0 HG00108 0 NA -0 HG00109 0 NA -0 HG00110 0 NA -0 HG00111 0 NA -0 HG00112 0 NA -0 HG00113 0 NA -0 HG00114 0 NA -0 HG00115 0 NA -0 HG00116 0 NA -0 HG00117 0 NA -0 HG00118 0 NA -0 HG00119 0 NA -0 HG00120 0 NA -0 HG00121 0 NA -0 HG00122 0 NA -0 HG00123 0 NA -0 HG00125 0 NA -0 HG00126 0 NA -0 HG00127 0 NA -0 HG00128 0 NA -0 HG00129 0 NA -0 HG00130 0 NA -0 HG00131 0 NA -0 HG00132 0 NA -0 HG00133 0 NA -0 HG00136 0 NA -0 HG00137 0 NA -0 HG00138 0 NA -0 HG00139 0 NA -0 HG00140 0 NA -0 HG00141 0 NA -0 HG00142 0 NA -0 HG00143 0 NA -0 HG00145 0 NA -0 HG00146 0 NA -0 HG00148 0 NA -0 HG00149 0 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NA +NA21126 NA21126 0 NA +NA21127 NA21127 0 NA +NA21128 NA21128 0 NA +NA21129 NA21129 0 NA +NA21130 NA21130 0 NA +NA21133 NA21133 0 NA +NA21135 NA21135 0 NA +NA21137 NA21137 0 NA +NA21141 NA21141 0 NA +NA21142 NA21142 0 NA +NA21143 NA21143 0 NA +NA21144 NA21144 0 NA From 44162d2be679b02b0faab482595d92af7e31b04e Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 11:27:02 +0100 Subject: [PATCH 19/33] update SNPs to match targene-pipeline --- test/snps.csv | 6 +++--- 1 file changed, 3 insertions(+), 3 deletions(-) diff --git a/test/snps.csv b/test/snps.csv index 3e9efce..716a3bb 100644 --- a/test/snps.csv +++ b/test/snps.csv @@ -1,4 +1,4 @@ RSID,CHR,POS -1:9295582:A:G,1,9295582 -2:14042743:A:G,2,14042743 -3:194089945:G:A,3,194089945 +1:238411180:T:C,1,238411180 +2:14983:G:A,2,14983 +3:3502414:T:C,3,3502414 From 8de3019dca177598a1166f6d4408bd1e69d003de Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 11:27:12 +0100 Subject: [PATCH 20/33] add RUN_TYPE --- test/test.config | 1 + 1 file changed, 1 insertion(+) diff --git a/test/test.config b/test/test.config index e19c3fa..eb6b487 100644 --- a/test/test.config +++ b/test/test.config @@ -1,5 +1,6 @@ params { COHORT = "UKB" + RUN_TYPE = "TEST" INPUT_SNPS = "${projectDir}/test/snps.csv" BGEN_FILES = "${projectDir}/test/bgen/ukb_chr*.{bgen,sample,bgen.bgi}" BED_FILES = "${projectDir}/test/bed/ukb_chr*.{bed,bim,fam}" From d44e14fbc2d3ce299f7fd860054f53b429c8dd7c Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 12:10:21 +0100 Subject: [PATCH 21/33] add new profiles --- nextflow.config | 12 ++++++++++++ 1 file changed, 12 insertions(+) diff --git a/nextflow.config b/nextflow.config index a113f1e..3f91c79 100644 --- a/nextflow.config +++ b/nextflow.config @@ -10,6 +10,18 @@ profiles { eddie { includeConfig 'conf/eddie.config' } + ci { + includeConfig 'conf/ci.config' + } + local { + includeConfig 'conf/local.config' + } + docker { + includeConfig 'conf/docker.config' + } + singularity { + includeConfig 'conf/singularity.config' + } } trace { From 480e9929911afafe811cc5290ebfcf41c023ca66 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 12:11:09 +0100 Subject: [PATCH 22/33] add first try CI yaml --- .github/workflows/CI.yaml | 32 ++++++++++++++++++++++++++++++++ 1 file changed, 32 insertions(+) create mode 100644 .github/workflows/CI.yaml diff --git a/.github/workflows/CI.yaml b/.github/workflows/CI.yaml new file mode 100644 index 0000000..8a2d997 --- /dev/null +++ b/.github/workflows/CI.yaml @@ -0,0 +1,32 @@ +name: CI +on: + - push + - pull_request +concurrency: + # Skip intermediate builds: always. + # Cancel intermediate builds: only if it is a pull request build. + group: ${{ github.workflow }}-${{ github.ref }} + cancel-in-progress: ${{ startsWith(github.ref, 'refs/pull/') }} +jobs: + test: + name: Test ${{ matrix.testrun }} -- ${{ github.event_name }} + runs-on: ubuntu-latest + strategy: + fail-fast: false + matrix: + testrun: + - "test/test1.py" + steps: + - uses: actions/checkout@v3 + - name: Set up Python + uses: actions/setup-python@v3 + with: + python-version: '3.11' + - name: Install Python dependencies + run: | + python -m pip install --upgrade pip + pip install -r test/requirements.txt + - name: Set up nextflow + uses: nf-core/setup-nextflow@v1.2.0 + - name: Run tests + run: python test/${{ matrix.testrun }} From ae9cf2ebcba2d4b509df40dd7c3fde6e979f68c0 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 12:11:43 +0100 Subject: [PATCH 23/33] add CI config --- conf/ci.config | 17 +++++++++++++++++ 1 file changed, 17 insertions(+) create mode 100644 conf/ci.config diff --git a/conf/ci.config b/conf/ci.config new file mode 100644 index 0000000..abb91a7 --- /dev/null +++ b/conf/ci.config @@ -0,0 +1,17 @@ +docker { + runOptions = '-u $(id -u):$(id -g)' +} + +includeConfig 'docker.config' + +process { + memory = '4G' + + withLabel: bigmem { + memory = '4G' + } + + withLabel: multithreaded { + cpus = 1 + } +} From af0b75f185279f5e46642f45f4fa4c16df72b093 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 12:11:54 +0100 Subject: [PATCH 24/33] add docker config --- conf/docker.config | 8 ++++++++ 1 file changed, 8 insertions(+) create mode 100644 conf/docker.config diff --git a/conf/docker.config b/conf/docker.config new file mode 100644 index 0000000..9458671 --- /dev/null +++ b/conf/docker.config @@ -0,0 +1,8 @@ +includeConfig 'container.config' + +docker { + enabled = true + pullTimeout = '1h' + envWhitelist = 'TMPDIR' + fixOwnership = true +} \ No newline at end of file From de37810dd3c3fbf2bf6ba3299eed8b527ddeee9e Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 12:12:01 +0100 Subject: [PATCH 25/33] add local config --- conf/local.config | 17 +++++++++++++++++ 1 file changed, 17 insertions(+) create mode 100644 conf/local.config diff --git a/conf/local.config b/conf/local.config new file mode 100644 index 0000000..d474157 --- /dev/null +++ b/conf/local.config @@ -0,0 +1,17 @@ +process { + // Use $TMPDIR for process execution + scratch = true +} + +env { + // Required for Java processes + MALLOC_ARENA_MAX = 1 +} + +singularity { + runOptions = '-p -B "$TMPDIR"' +} + +includeConfig 'singularity.config' +includeConfig 'container.config' +includeConfig 'base.config' \ No newline at end of file From 1e760c6ed7966dea62dd9ac06e62a20e987409e2 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 12:12:14 +0100 Subject: [PATCH 26/33] python requirements for tests --- test/requirements.txt | 6 ++++++ 1 file changed, 6 insertions(+) create mode 100644 test/requirements.txt diff --git a/test/requirements.txt b/test/requirements.txt new file mode 100644 index 0000000..21f3049 --- /dev/null +++ b/test/requirements.txt @@ -0,0 +1,6 @@ +numpy==2.1.1 +pandas==2.2.3 +python-dateutil==2.9.0.post0 +pytz==2024.2 +six==1.16.0 +tzdata==2024.2 From fac12d81cd84a5bcccd64b87d8721c2cca9f096e Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 12:12:27 +0100 Subject: [PATCH 27/33] first end-to-end test script --- test/test1.py | 17 +++++++++++++++++ 1 file changed, 17 insertions(+) create mode 100644 test/test1.py diff --git a/test/test1.py b/test/test1.py new file mode 100644 index 0000000..8514b37 --- /dev/null +++ b/test/test1.py @@ -0,0 +1,17 @@ +import subprocess +import pandas as pd +import numpy as np + +# Define the command to run as a list +command = ["nextflow","run","main.nf","-c","test/test.config","-profile","ci"] + +# Run the command and capture the output +result = subprocess.run(command, capture_output=True, text=True) + +# Check if the command was successful +if result.returncode == 0: + # Print the standard output from the command + print("Command output:\n", result.stdout) +else: + # Print the error if the command failed + print("Command failed with error:\n", result.stderr) From 2d56faf36c30ac4b75f1659d733437d1006507f0 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 12:22:35 +0100 Subject: [PATCH 28/33] update path --- .github/workflows/CI.yaml | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/.github/workflows/CI.yaml b/.github/workflows/CI.yaml index 8a2d997..cf60fda 100644 --- a/.github/workflows/CI.yaml +++ b/.github/workflows/CI.yaml @@ -15,7 +15,7 @@ jobs: fail-fast: false matrix: testrun: - - "test/test1.py" + - "test1.py" steps: - uses: actions/checkout@v3 - name: Set up Python From c8f2b2d0e66472c8d703446d781bdcb79349b88f Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 13:10:29 +0100 Subject: [PATCH 29/33] update command-line argument to pytest --- .github/workflows/CI.yaml | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/.github/workflows/CI.yaml b/.github/workflows/CI.yaml index cf60fda..201380b 100644 --- a/.github/workflows/CI.yaml +++ b/.github/workflows/CI.yaml @@ -29,4 +29,4 @@ jobs: - name: Set up nextflow uses: nf-core/setup-nextflow@v1.2.0 - name: Run tests - run: python test/${{ matrix.testrun }} + run: pytest test/${{ matrix.testrun }} From 5364b9c1141f51cdd6efddb772c10ee652ea20f8 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 13:10:36 +0100 Subject: [PATCH 30/33] add pytest --- test/requirements.txt | 4 ++++ 1 file changed, 4 insertions(+) diff --git a/test/requirements.txt b/test/requirements.txt index 21f3049..1843881 100644 --- a/test/requirements.txt +++ b/test/requirements.txt @@ -1,5 +1,9 @@ +iniconfig==2.0.0 numpy==2.1.1 +packaging==24.1 pandas==2.2.3 +pluggy==1.5.0 +pytest==8.3.3 python-dateutil==2.9.0.post0 pytz==2024.2 six==1.16.0 From e44b5cd11155f6883dafef08af3837ca91de54f4 Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 13:10:47 +0100 Subject: [PATCH 31/33] add additional teste using pytest --- test/test1.py | 26 +++++++++++++++++--------- 1 file changed, 17 insertions(+), 9 deletions(-) diff --git a/test/test1.py b/test/test1.py index 8514b37..151e48c 100644 --- a/test/test1.py +++ b/test/test1.py @@ -1,17 +1,25 @@ import subprocess import pandas as pd -import numpy as np +import pytest +import os # Define the command to run as a list command = ["nextflow","run","main.nf","-c","test/test.config","-profile","ci"] -# Run the command and capture the output -result = subprocess.run(command, capture_output=True, text=True) +# Run command to generate results first +@pytest.fixture(scope="module", autouse=True) +def generate_results(command): + result = subprocess.run(command, capture_output=True, text=True) + return result # Check if the command was successful -if result.returncode == 0: - # Print the standard output from the command - print("Command output:\n", result.stdout) -else: - # Print the error if the command failed - print("Command failed with error:\n", result.stderr) +def test_run_completed(generate_results): + assert generate_results.returncode == 0 + +def test_ld_block_output(generate_results): + ld_blocks = pd.read_csv("results/ld_blocks/snps_with_LD_blocks.csv") + assert len(ld_blocks.RSID)==3, "Expected 3 SNPs in output LD blocks file." + assert ld_blocks.columns == ['RSID','CHR','POS','LDblock_lower','LDblock_upper','LDblock_length','lower_bound','upper_bound'], "Column names do not match expected names in LD blocks file." + +def test_screeplot_exists(generate_results): + assert os.path.exists("results/pca/ScreePlot.pdf"), "Expected output ScreePlot from pipeline run." From d54701e1112f49f4edaf84edd8f30f213feacd4b Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 13:15:00 +0100 Subject: [PATCH 32/33] move command declaration into function --- test/test1.py | 6 ++---- 1 file changed, 2 insertions(+), 4 deletions(-) diff --git a/test/test1.py b/test/test1.py index 151e48c..fa14537 100644 --- a/test/test1.py +++ b/test/test1.py @@ -3,12 +3,10 @@ import pytest import os -# Define the command to run as a list -command = ["nextflow","run","main.nf","-c","test/test.config","-profile","ci"] - # Run command to generate results first @pytest.fixture(scope="module", autouse=True) -def generate_results(command): +def generate_results(): + command = ["nextflow","run","main.nf","-c","test/test.config","-profile","ci"] result = subprocess.run(command, capture_output=True, text=True) return result From c3e1bf0d7789d38449e882174f584b47f7a2a7de Mon Sep 17 00:00:00 2001 From: roskamsh Date: Thu, 3 Oct 2024 13:25:44 +0100 Subject: [PATCH 33/33] update tests --- test/test1.py | 10 +++++++--- 1 file changed, 7 insertions(+), 3 deletions(-) diff --git a/test/test1.py b/test/test1.py index fa14537..2e52352 100644 --- a/test/test1.py +++ b/test/test1.py @@ -8,6 +8,9 @@ def generate_results(): command = ["nextflow","run","main.nf","-c","test/test.config","-profile","ci"] result = subprocess.run(command, capture_output=True, text=True) + print(result.stdout) + if result.stderr: + print(result.stderr) return result # Check if the command was successful @@ -16,8 +19,9 @@ def test_run_completed(generate_results): def test_ld_block_output(generate_results): ld_blocks = pd.read_csv("results/ld_blocks/snps_with_LD_blocks.csv") - assert len(ld_blocks.RSID)==3, "Expected 3 SNPs in output LD blocks file." - assert ld_blocks.columns == ['RSID','CHR','POS','LDblock_lower','LDblock_upper','LDblock_length','lower_bound','upper_bound'], "Column names do not match expected names in LD blocks file." + assert len(ld_blocks.RSID) == 3, "Expected 3 SNPs in output LD blocks file." + assert len(ld_blocks.columns) == 8, "Expected 8 columns in LD blocks file." + assert ld_blocks.columns.tolist() == ['RSID','CHR','POS','LDblock_lower','LDblock_upper','LDblock_length','lower_bound','upper_bound'], "Column names do not match expected in LD blocks file." def test_screeplot_exists(generate_results): - assert os.path.exists("results/pca/ScreePlot.pdf"), "Expected output ScreePlot from pipeline run." + assert os.path.exists("results/pca/ScreePlot.pdf"), "Expected file ScreePlot.pdf from pipeline run."