Dereplicator+ Adducts in negative mode

[froz9]

Hi,

I am running Dereplicator+ on an .MGF file derived from negative mode data. The input file contains negative charges, however, the results only show positive ion mode adducts.

I have reviewed the Dereplicator+ paper, which states:
"To assess the capability of DEREPLICATOR+ in identifying compounds in the negative ionization modes, we analyzed 341 additional spectra in the GNPS spectral library collected in the ESI (-) mode. DEREPLICATOR+ search correctly identified 88 (26%) of these compounds as top predictions (Supplementary Data 9)."

This statement suggests that Dereplicator+ is capable of analyzing data in negative ionization mode (ESI-).

Could you please provide guidance on how to address this issue and obtain correct adduct predictions for my negative mode data?

Thank you in advance.