Low expression TFs in top regulons and reducing NES. #468
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DominicShayler
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* General SCENIC questions
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Hello,
I've been recently manipulating the NES threshold in my runs to see if some major expected TFs in my tissue would appear in my results with slightly lower threshholds. How problematic is a NES of 2 vs 3? Second part is one of my "top 5' regulons for a given cell cluster seems to be based on a gene that's barely expressed in 2 cells. What would make this shake out and not get removed in the filtering?
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