diff --git a/CHANGES/10119.bugfix.rst b/CHANGES/10119.bugfix.rst
new file mode 100644
index 00000000000..86d2511f5b5
--- /dev/null
+++ b/CHANGES/10119.bugfix.rst
@@ -0,0 +1 @@
+Response is now always True, instead of using MutableMapping behaviour (False when map is empty)
diff --git a/aiohttp/web_response.py b/aiohttp/web_response.py
index 2feffba9e68..88a1d145da0 100644
--- a/aiohttp/web_response.py
+++ b/aiohttp/web_response.py
@@ -504,6 +504,9 @@ def __hash__(self) -> int:
     def __eq__(self, other: object) -> bool:
         return self is other
 
+    def __bool__(self) -> bool:
+        return True
+
 
 class Response(StreamResponse):
 
diff --git a/tests/test_web_request.py b/tests/test_web_request.py
index 0086d9b1688..932e3efd02d 100644
--- a/tests/test_web_request.py
+++ b/tests/test_web_request.py
@@ -287,6 +287,7 @@ def test_match_info() -> None:
 def test_request_is_mutable_mapping() -> None:
     req = make_mocked_request("GET", "/")
     assert isinstance(req, MutableMapping)
+    assert req  # even when the MutableMapping is empty, request should always be True
     req["key"] = "value"
     assert "value" == req["key"]
 
diff --git a/tests/test_web_response.py b/tests/test_web_response.py
index dff883d4570..f8cf233e148 100644
--- a/tests/test_web_response.py
+++ b/tests/test_web_response.py
@@ -93,6 +93,7 @@ def test_stream_response_eq() -> None:
 def test_stream_response_is_mutable_mapping() -> None:
     resp = web.StreamResponse()
     assert isinstance(resp, collections.abc.MutableMapping)
+    assert resp  # even when the MutableMapping is empty, response should always be True
     resp["key"] = "value"
     assert "value" == resp["key"]