diff --git a/.github/workflows/package.yml b/.github/workflows/package.yml
index 9549dc8b..33e900af 100644
--- a/.github/workflows/package.yml
+++ b/.github/workflows/package.yml
@@ -62,7 +62,7 @@ jobs:
         - 3.7
         - 3.8
         - 3.9
-        - pypy-3.6
+        # - pypy-3.6
         - pypy-3.7
     steps:
     - name: Checkout code
diff --git a/CHANGELOG.md b/CHANGELOG.md
index d567365d..d1418259 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -6,7 +6,22 @@ and this project adheres to [Semantic Versioning](http://semver.org/spec/v2.0.0.
 
 
 ## [Unreleased]
-[Unreleased]: https://github.com/althonos/pyhmmer/compare/v0.4.9...HEAD
+[Unreleased]: https://github.com/althonos/pyhmmer/compare/v0.4.10...HEAD
+
+
+## [v0.4.10] - 2021-12-06
+[v0.4.10]: https://github.com/althonos/pyhmmer/compare/v0.4.9...v0.4.10
+
+### Added
+- `entropy` and `relative_entropy` methods to `easel.VectorF` to compute the Shannon entropy of a vector and the Kullback-Leibler divergence of two vectors.
+- `mean_match_entropy`, `mean_match_information` and `mean_match_relative_entropy` methods to `plan7.HMM` to get information statistics of an HMM model.
+- `match_occupancy` method to `plan7.HMM` to compute the occupancy for each match state as an `easel.VectorF`.
+
+### Fixed
+- `plan7.Builder.build_msa` using the gap-open and gap-extend probabilities instead of the MSA itself to compute the transition probabilities for the new HMM.
+
+### Changed
+- `plan7.Builder.build` will now only load the score system once and reuse it unless a different score system is requested between calls.
 
 
 ## [v0.4.9] - 2021-11-11
diff --git a/pyhmmer/__init__.py b/pyhmmer/__init__.py
index dc9566fb..26bbf8b6 100644
--- a/pyhmmer/__init__.py
+++ b/pyhmmer/__init__.py
@@ -25,7 +25,7 @@
 
 __author__ = "Martin Larralde <martin.larralde@embl.de>"
 __license__ = "MIT"
-__version__ = "0.4.9"
+__version__ = "0.4.10"
 __all__ = [
     errors.__name__,
     easel.__name__,