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TODO.md

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call

  • define INFO:tier based on code in report
  • add CRAM support

normalise

  • migrate to pyvcf where possible
  • Should document how we combine variants

merge

  • migrate to pyvcf where possible (started in dev/merge2.py)
  • force the same sample names in the same order in mity and HC?
  • are there any VCF format 4.1 vs 4.2 fields that clash. eg the type of the variable changes?

report

  • mity report fails if mity normalise hasn't been run, so consider making this mandatory & dropping mity normalise
  • Check if report works with multiple VCFs
  • update mitomap annotations

misc

  • use logging.info, logging.debug, logging.warning, logging.error where possible
  • hg19 support: after running BLAST, there are more sequence differences than initially appreciated. This is scheduled for deprecation

DNAnexus

  • migrate app code to use the latest mity. either via an asset, or Docker image.