Multiple image analysis issues

[genemark2000]

We sometimes encounter issues where if we do multiple image analysis with the original image plus label images in the folder, the "area" doesn't get calculated correctly. We found out that depends on which software we exported the images to be analyzed (before Cellpose). If we just perform the label images "single" without using the original image, the area calculation is fine.
We've always exported the images in Tiff so not sure why it works sometimes and but not other times and it only gives us problem when we try to do 'original' plus "label" images. Have you seen this problem before?