README.md

Global HTA Evidence Open

This repository contains code and analysis made open source from Global HTA Evidence.

Rpackages

flexsurvPlus

This package facilitates performing survival analysis to support the creation of Excel based economic models by providing helper functions to use alongside the flexsurv package.

installation code

devtools::install_github(
  "roche/Global-HTA-Evidence-Open", 
  subdir = "/Rpackages/flexsurvPlus"
  )

documentation

https://roche.github.io/Global-HTA-Evidence-Open/Rpackages/flexsurvPlus/docs/index.html

gemtcPlus

This package implements some convinience functions for perfoming Bayesian NMA using the gemtc package for standard models (binary data, hazard ratio data). It also contains some more advanced models for time-to-event data with time varying hazard ratios, such as fractional polynomial NMAs and piecewise exponential NMA models.

Documentation

https://roche.github.io/Global-HTA-Evidence-Open/Rpackages/gemtcPlus/docs/index.html

Installation code

First ensure you have installed from CRAN gemtc package and rjags package and that you also have JAGS installed.

devtools::install_github(
  "roche/Global-HTA-Evidence-Open", 
  subdir = "Rpackages/gemtcPlus"
  )

MAIC

This package facilitates performing matching-adjusted indirect comparison (MAIC) anaylsis for a disconnected treatment network where the endpoint of interest is either time-to-event (e.g. overall survival) or binary (e.g. objective tumor response).

Documentation

https://roche.github.io/Global-HTA-Evidence-Open/Rpackages/MAIC/docs/index.html

Installation code

devtools::install_github(
  "roche/Global-HTA-Evidence-Open", 
  subdir = "Rpackages/MAIC"
  )

rpsftmPlus

This package implements some convinience functions for working with the rpsftm package and general analysis of trials affected by treatment switching.

Documentation

https://roche.github.io/Global-HTA-Evidence-Open/Rpackages/rpsftmPlus/docs/index.html

Installation code

devtools::install_github(
  "roche/Global-HTA-Evidence-Open", 
  subdir = "Rpackages/rpsftmPlus"
  )