diff --git a/crates/bevy_ui/src/focus.rs b/crates/bevy_ui/src/focus.rs
index 08d488de34bb9..7dd4defc1eefb 100644
--- a/crates/bevy_ui/src/focus.rs
+++ b/crates/bevy_ui/src/focus.rs
@@ -252,9 +252,13 @@ pub fn ui_focus_system(
             // The mouse position relative to the node
             // (0., 0.) is the top-left corner, (1., 1.) is the bottom-right corner
             // Coordinates are relative to the entire node, not just the visible region.
-            let relative_cursor_position = camera_cursor_positions
-                .get(&camera_entity)
-                .map(|cursor_position| (*cursor_position - node_rect.min) / node_rect.size());
+            let relative_cursor_position =
+                camera_cursor_positions
+                    .get(&camera_entity)
+                    .and_then(|cursor_position| {
+                        (node_rect.size().cmpgt(Vec2::ZERO).all())
+                            .then_some((*cursor_position - node_rect.min) / node_rect.size())
+                    });
 
             // If the current cursor position is within the bounds of the node's visible area, consider it for
             // clicking