diff --git a/CHT/README.md b/CHT/README.md index 03c6b68..8c324ad 100644 --- a/CHT/README.md +++ b/CHT/README.md @@ -166,7 +166,7 @@ For example, if the goal is to identify histone-mark QTLs, the target regions should be ChIP-seq peaks, and the test SNPs should be SNPs that are near-to or within the ChIP-seq peaks. -Note (added 4/25/2016): the target regions for a single test regions should be +*Note (added 4/25/2016):* the target regions for a single test regions should be non-overlapping. Overlapping target regions can cause some reads to be counted multiple times in a single test and inflate the test statistic. We plan to add a check for this to the extract haplotype