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A one-sided variant matching portal to support rare disease research

The One-Sided Matching Portal (OSMP) enables researchers to query patient variant and phenotype data from many different sources simultaneously. Acting as a hub connecting disparate data sources, the portal processes user queries, routes them to their respective endpoints with appropriate authorization, and amalgamates their results into a single, easily-searchable collection displayed in a user-friendly interface. By allowing researchers to search patient data from several research institutions with a single query, the OSMP can significantly speed up the process of rare disease “matching” across institutions and datasets.

The instructions for setting up the local development environment and a description of the staging and production instance can be found in the docs folder.