diff --git a/newsfragments/742.bugfix b/newsfragments/742.bugfix
new file mode 100644
index 000000000..dfcb2b06e
--- /dev/null
+++ b/newsfragments/742.bugfix
@@ -0,0 +1,2 @@
+``FormatCBFMini``: when parsing header lines for a timestamp, avoid clashes with Windows paths.
+
diff --git a/src/dxtbx/format/FormatCBFMini.py b/src/dxtbx/format/FormatCBFMini.py
index 8e24f1808..4947fecd3 100644
--- a/src/dxtbx/format/FormatCBFMini.py
+++ b/src/dxtbx/format/FormatCBFMini.py
@@ -82,7 +82,11 @@ def _get_timestamp_from_raw_header(
             header = header.splitlines()
         timestamp = None
         for record in header:
-            if len(record[1:].split()) <= 2 and record.count(":") == 2:
+            if (
+                len(record[1:].split()) <= 2
+                and record.count(":") == 2
+                and "Image_path" not in record
+            ):
                 timestamp = datetime.datetime.fromisoformat(record[1:].strip())
                 break
         return timestamp
@@ -100,7 +104,11 @@ def _start(self):
             if record[:1] != "#":
                 continue
 
-            if len(record[1:].split()) <= 2 and record.count(":") == 2:
+            if (
+                len(record[1:].split()) <= 2
+                and record.count(":") == 2
+                and "Image_path" not in record
+            ):
                 self._cif_header_dictionary["timestamp"] = record[1:].strip()
                 continue