diff --git a/CMakeLists.txt b/CMakeLists.txt
index b02d42746..4d384fa03 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -25,6 +25,11 @@ if(BUILD_MQT_QMAP_BINDINGS)
       ON
       CACHE BOOL "Prevent multiple searches for Python and instead cache the results.")
 
+  if(DISABLE_GIL)
+    message(STATUS "Disabling Python GIL")
+    add_compile_definitions(Py_GIL_DISABLED)
+  endif()
+
   # top-level call to find Python
   find_package(
     Python 3.8 REQUIRED
diff --git a/pyproject.toml b/pyproject.toml
index b5d558f25..9f35fcb07 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -128,6 +128,13 @@ sdist.exclude = [
 BUILD_MQT_QMAP_TESTS = "OFF"
 BUILD_MQT_QMAP_BINDINGS = "ON"
 
+[[tool.scikit-build.overrides]]
+if.python-version = ">=3.13"
+if.abi-flags = "t"
+if.platform-system = "win32"
+inherit.cmake.define = "append"
+cmake.define.DISABLE_GIL = "1"
+
 
 [tool.check-sdist]
 sdist-only = ["src/mqt/qmap/_version.py"]