diff --git a/cwltool/factory.py b/cwltool/factory.py
index eaf98e3cf..7bc320462 100644
--- a/cwltool/factory.py
+++ b/cwltool/factory.py
@@ -1,12 +1,21 @@
+"""Wrap a CWL document as a callable Python object."""
+
+import argparse
+import functools
 import os
+import sys
 from typing import Any, Optional, Union
 
 from . import load_tool
-from .context import LoadingContext, RuntimeContext
+from .argparser import arg_parser
+from .context import LoadingContext, RuntimeContext, getdefault
 from .errors import WorkflowException
 from .executors import JobExecutor, SingleJobExecutor
+from .main import find_default_container
 from .process import Process
-from .utils import CWLObjectType
+from .resolver import tool_resolver
+from .secrets import SecretStore
+from .utils import DEFAULT_TMP_PREFIX, CWLObjectType
 
 
 class WorkflowStatus(Exception):
@@ -25,11 +34,15 @@ def __init__(self, t: Process, factory: "Factory") -> None:
         self.t = t
         self.factory = factory
 
-    def __call__(self, **kwargs):
-        # type: (**Any) -> Union[str, Optional[CWLObjectType]]
-        runtime_context = self.factory.runtime_context.copy()
-        runtime_context.basedir = os.getcwd()
-        out, status = self.factory.executor(self.t, kwargs, runtime_context)
+    def __call__(self, **kwargs: Any) -> Union[str, Optional[CWLObjectType]]:
+        """
+        Execute the process.
+
+        :raise WorkflowStatus: If the result is not a success.
+        """
+        if not self.factory.runtime_context.basedir:
+            self.factory.runtime_context.basedir = os.getcwd()
+        out, status = self.factory.executor(self.t, kwargs, self.factory.runtime_context)
         if status != "success":
             raise WorkflowStatus(out, status)
         else:
@@ -47,18 +60,24 @@ def __init__(
         executor: Optional[JobExecutor] = None,
         loading_context: Optional[LoadingContext] = None,
         runtime_context: Optional[RuntimeContext] = None,
+        argsl: Optional[list[str]] = None,
+        args: Optional[argparse.Namespace] = None,
     ) -> None:
+        """Create a CWL Process factory from a CWL document."""
+        if argsl is not None:
+            args = arg_parser().parse_args(argsl)
         if executor is None:
-            executor = SingleJobExecutor()
-        self.executor = executor
+            self.executor: JobExecutor = SingleJobExecutor()
+        else:
+            self.executor = executor
         if runtime_context is None:
-            self.runtime_context = RuntimeContext()
+            self.runtime_context = RuntimeContext(vars(args) if args else {})
+            self._fix_runtime_context()
         else:
             self.runtime_context = runtime_context
         if loading_context is None:
-            self.loading_context = LoadingContext()
-            self.loading_context.singularity = self.runtime_context.singularity
-            self.loading_context.podman = self.runtime_context.podman
+            self.loading_context = LoadingContext(vars(args) if args else {})
+            self._fix_loading_context(self.runtime_context)
         else:
             self.loading_context = loading_context
 
@@ -68,3 +87,45 @@ def make(self, cwl: Union[str, dict[str, Any]]) -> Callable:
         if isinstance(load, int):
             raise WorkflowException("Error loading tool")
         return Callable(load, self)
+
+    def _fix_loading_context(self, runtime_context: RuntimeContext) -> None:
+        self.loading_context.resolver = getdefault(self.loading_context.resolver, tool_resolver)
+        self.loading_context.singularity = runtime_context.singularity
+        self.loading_context.podman = runtime_context.podman
+
+    def _fix_runtime_context(self) -> None:
+        self.runtime_context.basedir = os.getcwd()
+        self.runtime_context.find_default_container = functools.partial(
+            find_default_container, default_container=None, use_biocontainers=None
+        )
+
+        if sys.platform == "darwin":
+            default_mac_path = "/private/tmp/docker_tmp"
+            if self.runtime_context.tmp_outdir_prefix == DEFAULT_TMP_PREFIX:
+                self.runtime_context.tmp_outdir_prefix = default_mac_path
+
+        for dirprefix in ("tmpdir_prefix", "tmp_outdir_prefix", "cachedir"):
+            if (
+                getattr(self.runtime_context, dirprefix)
+                and getattr(self.runtime_context, dirprefix) != DEFAULT_TMP_PREFIX
+            ):
+                sl = (
+                    "/"
+                    if getattr(self.runtime_context, dirprefix).endswith("/")
+                    or dirprefix == "cachedir"
+                    else ""
+                )
+                setattr(
+                    self.runtime_context,
+                    dirprefix,
+                    os.path.abspath(getattr(self.runtime_context, dirprefix)) + sl,
+                )
+                if not os.path.exists(os.path.dirname(getattr(self.runtime_context, dirprefix))):
+                    try:
+                        os.makedirs(os.path.dirname(getattr(self.runtime_context, dirprefix)))
+                    except Exception as e:
+                        print("Failed to create directory: %s", e)
+
+        self.runtime_context.secret_store = getdefault(
+            self.runtime_context.secret_store, SecretStore()
+        )