From 67368d6763a59930bd845b5a9ff4c38834cef458 Mon Sep 17 00:00:00 2001 From: Maria Koval Date: Mon, 22 Jul 2024 12:35:40 -0300 Subject: [PATCH] changes about prs module --- how_it_works.html | 2 +- index.html | 3 ++- 2 files changed, 3 insertions(+), 2 deletions(-) diff --git a/how_it_works.html b/how_it_works.html index 9105af2..b2903a0 100644 --- a/how_it_works.html +++ b/how_it_works.html @@ -85,7 +85,7 @@

How it works

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The Just DNA-Seq platform consists of OakVar (Open-source Genomic Variant Analysis Platform) modules, bioinformatics pipelines, and additional libraries. One can realign and annotate the genome of interest employing Just DNA-Seq tools to retrieve polygenic risk scores (PRS), information about variants associated with age-related diseases or major life threatening risks and longevity-associated variants present in genome.

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The Just DNA-Seq platform consists of OakVar (Open-source Genomic Variant Analysis Platform) modules, bioinformatics pipelines, and additional libraries. One can realign and annotate the genome of interest employing Just DNA-Seq tools to retrieve information about variants associated with age-related diseases or major life threatening risks and longevity-associated variants present in genome.

diff --git a/index.html b/index.html index 7ad15b8..d511dd1 100644 --- a/index.html +++ b/index.html @@ -186,6 +186,7 @@

At the moment we have the following modules i
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(Currently depricated and removed)

Longevity PRS report is based on existing longevity polygenic scores. At the moment, our best performing PRS is implements the score presented in [PMC8087277] and comprises 330 variants. This PRS was shown to be significantly associated with cognitively healthy aging and with prolonged survival. While it is not enough to have “centenarian” genes to become one, they are still needed to cut down major health risks and therefore gain longevity escape velocity.
Github repository: just_prs
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At the moment we have the following modules i
- Genetics plays an important role in lipid metabolism and the development of heart disease. Genes control the production, transport, and metabolism of cholesterol and other lipids. Lipid metabolism plays an important role in the development of heart disease, and this risk increases with age. This report contains data of the PRS of Coronary atherosclerosis development (PGS001839), and the list with genes, associated with an increased risk of CAD. + Genetics plays an important role in lipid metabolism and the development of heart disease. Genes control the production, transport, and metabolism of cholesterol and other lipids. Lipid metabolism plays an important role in the development of heart disease, and this risk increases with age. This report contains the list with genes, associated with an increased risk of CAD.
Github repository: just_lipidmetabolism