Re-organize the child term of extracellular matrix (GO:0031012)

[DaiqingChen]

Change parent term

The 4 direct child terms of extracellular matrix (GO:0031012) are:

• Basement membrane (GO:0005604)
• Interstitial matrix (GO:0005614)
• Basement membrane/interstitial matrix interface (NTR Add term Basement membrane/interstitial matrix interface #29456)
• Specialized extracellular matrix (NTR Add term Specialized extracellular matrix #29265)

Reason for changing parent term:
To better describe the current understanding of ECM components and compartments.
We propose to keep the extracellular matrix parent term currently referring to the metazoan ECM as the generic physiological "cellular compartment" based on GO's terminology. The extracellular matrix exists in three forms, each form is comprised of different molecules: the Interstitial matrix (GO:0005614), the Basement membrane (GO:0005604), and a compartment that is located at the interface of the interstitial matrix and the basement membrane.

Reference, in format PMID:
PMID: 39223427, PMID: 33605520

Add new terms as child terms

Add new child terms for Basement membrane (GO: 0005604)

• Collagenous component of basement membrane(NTR: Add term Collagenous component of basement membrane #29472)
  Child term: Chicken-wire-like collagen trimer (NTR Add term Chicken-wire-like collagen network  #29401), Basement membrane hexagonal collagen network (NTR Add term Hexagonal collagen network of basement membrane #29402), Multiplexin collagen trimer (NTR Add term multiplexin collagen trimer #29469), Collagen type XXVIII trimer (GO:19990326)

• Non-collagenous component of basement membrane(NTR Add term Non-collagenous component of basement membrane #29491)
  Child term: Gel phase of basement membrane(NTR Add term Gel phase of basement membrane #29268), Solid phase of basement membrane (To be built)

Add new child term of Interstitial matrix (GO:0005614)

• Collagenous component of interstitial matrix (NTR: Add term Collagenous component of interstitial matrix #29473)
  Child terms: Interstitial hexagonal network collagen (Term name and definition update: collagen sheet (GO:0098646) to interstitial hexagonal collagen network #29415), Fibrillar collagen trimer (Textual name update: banded collagen fibril (GO:0098643) to Fibrillar collagen complex #29474), FACIT collagen complex (NTR Add term FACIT collagen complex #29466), Collagen type XXVI trimer (GO:1990324)

• Non-collagenous component of interstitial matrix (NTR Add term Non-collagenous component of interstitial matrix #29492)
  child term: Interstitial matrix gel phase(NTR Add term Gel phase of interstitial matrix #29269), Interstitial matrix solid phase(To be build)

Reason for adding new terms

To reflect the different compartments found within the ECM and align with the GO CC terminology.
The collagenous and non-collagenous compartments of ECMs have distinct function and components. We kept the original idea of separating these compartments but propose to add more systematic annotations of the different compartments of the different types of ECMs. We are also obsoleting the term Collagen-containing extracellular matrix (GO:0062023) (#29475)

Other information

See slide 1: https://docs.google.com/presentation/d/1zxL0gt5vOynmJsS8BP-Xqs_0sTaEB8Zo/edit?usp=sharing&ouid=109267399050361021326&rtpof=true&sd=true

Slide screenshot