From 6fbb25d595c61a32e7b40b4340b5059b3949dad0 Mon Sep 17 00:00:00 2001
From: matthew-phelps <ma.phelps@gmail.com>
Date: Thu, 11 Apr 2024 06:36:24 +0000
Subject: [PATCH] =?UTF-8?q?Deploying=20to=20gh-pages=20from=20@=20hta-phar?=
 =?UTF-8?q?ma/ramnog@323252f41b5a02338ccad937b3c564fae04b63ec=20?=
 =?UTF-8?q?=F0=9F=9A=80?=
MIME-Version: 1.0
Content-Type: text/plain; charset=UTF-8
Content-Transfer-Encoding: 8bit

---
 404.html                               |   48 +-
 LICENSE-text.html                      |   46 +-
 LICENSE.html                           |   48 +-
 apple-touch-icon-120x120.png           |  Bin 27640 -> 27640 bytes
 apple-touch-icon-152x152.png           |  Bin 41317 -> 41317 bytes
 apple-touch-icon-180x180.png           |  Bin 55272 -> 55272 bytes
 apple-touch-icon-60x60.png             |  Bin 8514 -> 8514 bytes
 apple-touch-icon-76x76.png             |  Bin 12684 -> 12684 bytes
 apple-touch-icon.png                   |  Bin 55272 -> 55272 bytes
 articles/debugging.html                |   50 +-
 articles/dev_contribute.html           |  208 ++++
 articles/dev_devops.html               |  393 +++++++
 articles/ep_overview.html              |   50 +-
 articles/ep_spec_adam_data.html        |   50 +-
 articles/ep_spec_event_def.html        |   50 +-
 articles/ep_spec_label.html            |   52 +-
 articles/ep_spec_population_def.html   |   50 +-
 articles/ep_spec_strata_def.html       |   50 +-
 articles/ep_spec_treatment_arms.html   |   50 +-
 articles/example_ep_spec.html          |   50 +-
 articles/index.html                    |  113 +-
 articles/methods_criteria.html         |   50 +-
 articles/methods_stat.html             |   58 +-
 articles/qc.html                       |  352 ++++++
 articles/ramnog.html                   |  141 +--
 articles/results_datamodel.html        |   52 +-
 articles/results_datamodel2tfl.html    |   52 +-
 authors.html                           |   68 +-
 deps/bootstrap-5.3.1/bootstrap.min.css |    4 +-
 deps/bootstrap-5.3.1/font.css          | 1426 +-----------------------
 extra.css                              |    8 +
 favicon-16x16.png                      |  Bin 1446 -> 1446 bytes
 favicon-32x32.png                      |  Bin 3183 -> 3183 bytes
 index.html                             |   85 +-
 logo.png                               |  Bin 119790 -> 119790 bytes
 pkgdown.yml                            |    7 +-
 reference/dummy_fn.html                |   48 +-
 reference/figures/logo.png             |  Bin 119790 -> 119790 bytes
 reference/index.html                   |   46 +-
 search.json                            |    2 +-
 sitemap.xml                            |   11 +-
 41 files changed, 1682 insertions(+), 2036 deletions(-)
 create mode 100644 articles/dev_contribute.html
 create mode 100644 articles/dev_devops.html
 create mode 100644 articles/qc.html
 create mode 100644 extra.css

diff --git a/404.html b/404.html
index 6175ced..78130c1 100644
--- a/404.html
+++ b/404.html
@@ -16,7 +16,8 @@
 <link href="https://hta-pharma.github.io/ramnog/deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="https://hta-pharma.github.io/ramnog/deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="https://hta-pharma.github.io/ramnog/pkgdown.js"></script><meta property="og:title" content="Page not found (404)">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="https://hta-pharma.github.io/ramnog/pkgdown.js"></script><link href="https://hta-pharma.github.io/ramnog/extra.css" rel="stylesheet">
+<meta property="og:title" content="Page not found (404)">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
 <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script>
@@ -27,11 +28,11 @@
     <a href="https://hta-pharma.github.io/ramnog/#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="https://hta-pharma.github.io/ramnog/index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -41,42 +42,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="https://hta-pharma.github.io/ramnog/articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="https://hta-pharma.github.io/ramnog/reference/index.html">Reference</a>
+  <a class="nav-link" href="https://hta-pharma.github.io/ramnog/articles/ramnog.html">Quick start</a>
 </li>
 <li class="nav-item dropdown">
   <a href="https://hta-pharma.github.io/ramnog/#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="https://hta-pharma.github.io/ramnog/#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="https://hta-pharma.github.io/ramnog/articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -84,7 +81,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -104,7 +108,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/LICENSE-text.html b/LICENSE-text.html
index 59fd3aa..14ce243 100644
--- a/LICENSE-text.html
+++ b/LICENSE-text.html
@@ -1,16 +1,16 @@
 <!DOCTYPE html>
-<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><title>License • ramnog</title><!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="favicon-16x16.png"><link rel="icon" type="image/png" sizes="32x32" href="favicon-32x32.png"><link rel="apple-touch-icon" type="image/png" sizes="180x180" href="apple-touch-icon.png"><link rel="apple-touch-icon" type="image/png" sizes="120x120" href="apple-touch-icon-120x120.png"><link rel="apple-touch-icon" type="image/png" sizes="76x76" href="apple-touch-icon-76x76.png"><link rel="apple-touch-icon" type="image/png" sizes="60x60" href="apple-touch-icon-60x60.png"><script src="deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet"><script src="deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="pkgdown.js"></script><meta property="og:title" content="License"><meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
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 <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script>
 <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script>
 <![endif]--></head><body>
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -19,48 +19,50 @@
 
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto"><li class="nav-item">
-  <a class="nav-link" href="articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="reference/index.html">Reference</a>
+  <a class="nav-link" href="articles/ramnog.html">Quick start</a>
 </li>
 <li class="nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul><form class="form-inline my-2 my-lg-0" role="search">
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="search.json" id="search-input" placeholder="Search for" autocomplete="off"></form>
 
-      <ul class="navbar-nav"></ul></div>
+      <ul class="navbar-nav"><li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul></div>
 
     
   </div>
@@ -98,7 +100,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
 
 
     <footer><div class="pkgdown-footer-left">
-  <p></p><p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+  <p></p><p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/LICENSE.html b/LICENSE.html
index 9c1225f..b629de4 100644
--- a/LICENSE.html
+++ b/LICENSE.html
@@ -1,16 +1,16 @@
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-<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><title>MIT License • ramnog</title><!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="favicon-16x16.png"><link rel="icon" type="image/png" sizes="32x32" href="favicon-32x32.png"><link rel="apple-touch-icon" type="image/png" sizes="180x180" href="apple-touch-icon.png"><link rel="apple-touch-icon" type="image/png" sizes="120x120" href="apple-touch-icon-120x120.png"><link rel="apple-touch-icon" type="image/png" sizes="76x76" href="apple-touch-icon-76x76.png"><link rel="apple-touch-icon" type="image/png" sizes="60x60" href="apple-touch-icon-60x60.png"><script src="deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet"><script src="deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="pkgdown.js"></script><meta property="og:title" content="MIT License"><meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
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 <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script>
 <![endif]--></head><body>
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -19,48 +19,50 @@
 
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto"><li class="nav-item">
-  <a class="nav-link" href="articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="reference/index.html">Reference</a>
+  <a class="nav-link" href="articles/ramnog.html">Quick start</a>
 </li>
 <li class="nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul><form class="form-inline my-2 my-lg-0" role="search">
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="search.json" id="search-input" placeholder="Search for" autocomplete="off"></form>
 
-      <ul class="navbar-nav"></ul></div>
+      <ul class="navbar-nav"><li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul></div>
 
     
   </div>
@@ -68,7 +70,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
 <div class="row">
   <main id="main" class="col-md-9"><div class="page-header">
       <img src="logo.png" class="logo" alt=""><h1>MIT License</h1>
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/LICENSE.md" class="external-link"><code>LICENSE.md</code></a></small>
     </div>
 
 <div id="mit-license" class="section level1">
@@ -83,7 +85,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
 
 
     <footer><div class="pkgdown-footer-left">
-  <p></p><p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+  <p></p><p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/apple-touch-icon-120x120.png b/apple-touch-icon-120x120.png
index 0fe5e5e55c4047fa6651938ccfb0b3763becd906..f3685fa679b171ee87fe3df83609db9f0256df33 100644
GIT binary patch
delta 73
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M#XBsT+?kyZ08_jcb^rhX

delta 73
zcmexyo$<$Y#tBs%9BgJ%Wh^W2ZfrW3C2C+1Vqj)vYGP$%rfpzgWnf_Zs_pOOh-?{5
N8K>=bj*~mH^8vri7%>0<

diff --git a/apple-touch-icon-152x152.png b/apple-touch-icon-152x152.png
index 44aa055af4b0604cbb87546624b6a7f587dba959..aa56a5569109296e735df1d2515c91f977ce8475 100644
GIT binary patch
delta 96
zcmaEQi0SDerU_LX+-%A!lT!coY;4k7;AUtTVqj)vY-(j}rfpzgWni%A)uUzx1_sp<
m*NBpo#FA92-29Zxv`Pje10xe%0~1{g4VSk^*-!qqARhob)E~?M

delta 96
zcmaEQi0SDerU_LX9BgLNjLb8=H#X@la5Jz7F)*_-HL)@>*ETS)GBB7rx7U+_fkCyz
lHKHUXu_V<hH$Npat&+jWz{o_`0Eo~vJUL+cb@I0b`2dfW9t!{f

diff --git a/apple-touch-icon-180x180.png b/apple-touch-icon-180x180.png
index e0042233a14edead7c152c168bd97142fb9c74a1..3ae0cc01b26b4b0072eb443bfe626baed88f0d27 100644
GIT binary patch
delta 73
zcmaE{p83Uk<_T3C+-%CKPm|6{ZEV_jP1MjZ#K6qT*wo6{T-(6F%D{kS?o0E@9@k|s
OWl9eOc2BOno(}-ADj2c=

delta 73
zcmaE{p83Uk<_T3C9BgJX^V4}=Y;4+iP1L|5#K6qT)WpijLfgQ=%D^D`>fZ&EJ+8}O
O$_RD1%1o}jo(}-SwiuBB

diff --git a/apple-touch-icon-60x60.png b/apple-touch-icon-60x60.png
index f92c3ef4e0ade6a68ac570ec5e1cba22352792f9..21985af307ba9e016f708259100b940638a00547 100644
GIT binary patch
delta 94
zcmX@)bjWE!6$dw)vQjl$#LkUP+zM`nh9L%KR>r1Q#wOYZ237_Jrlp@(F)%QwmbgZg
jq$HN4TIJ@aWTsUz7#SFu=o*;lVrX#D@D`hVSs@<)5iA-=

delta 94
zcmX@)bjWE!6$b~KndE!kAL$#LxE0(CEJ6&-tV~U;j7+r+46F<cn3(1yFfcHvmbgZg
jq$HN4TIJ@aWTsUz7#SFu=o$bKx`yI-l{=F!E93(J78Dxf

diff --git a/apple-touch-icon-76x76.png b/apple-touch-icon-76x76.png
index 10690ab0e1c65a0dd3c291f7c8463dc3eba49c87..a3f03863356f5feb18c6ce8d18faf1515bc5171e 100644
GIT binary patch
delta 71
zcmeB4?n$0d#lg*{tW?bwv2$ZnsDY@VVTgg5m9eRnv5B^Uft7)QY3b)xliwJ~V9K~?
Lc#BPzHOvP9`FRua

delta 71
zcmeB4?n$0d#lgX5CRN6=^6ti_Py<l|ix2}dD^n9IBQtFS11kdq<5z8eC%-X}!IW{@
LZs#~z)-WFcCI}UL

diff --git a/apple-touch-icon.png b/apple-touch-icon.png
index e0042233a14edead7c152c168bd97142fb9c74a1..0c0b2f87d48f5d112c32baa7a7ca2165d0c79d51 100644
GIT binary patch
delta 73
zcmaE{p83Uk<_T3C+-%BfHQ93(Y;4+iP1MjZ#K6qT*wo6{LfgQ=%D~{$)tUDudt8^n
OlxglzOqyJIJs$wu+8Lw(

delta 73
zcmaE{p83Uk<_T3C9BgJX^V4}=Y;4+iP1L|5#K6qT)WpijLfgQ=%D^D`>fZ&EJ+8}O
O$_RD1%1o}jo(}-SwiuBB

diff --git a/articles/debugging.html b/articles/debugging.html
index 3fd4cb2..15ee508 100644
--- a/articles/debugging.html
+++ b/articles/debugging.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
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-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Debugging">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Debugging">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="active nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Debugging</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/debugging.Rmd" class="external-link"><code>vignettes/debugging.Rmd</code></a></small>
       <div class="d-none name"><code>debugging.Rmd</code></div>
     </div>
 
@@ -361,7 +365,7 @@ <h2 id="targets-style-debugging">Targets style debugging<a class="anchor" aria-l
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/dev_contribute.html b/articles/dev_contribute.html
new file mode 100644
index 0000000..c9bce2c
--- /dev/null
+++ b/articles/dev_contribute.html
@@ -0,0 +1,208 @@
+<!DOCTYPE html>
+<!-- Generated by pkgdown: do not edit by hand --><html lang="en">
+<head>
+<meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
+<meta charset="utf-8">
+<meta http-equiv="X-UA-Compatible" content="IE=edge">
+<meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no">
+<meta name="description" content="ramnog">
+<title>Contributing • ramnog</title>
+<!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="../favicon-16x16.png">
+<link rel="icon" type="image/png" sizes="32x32" href="../favicon-32x32.png">
+<link rel="apple-touch-icon" type="image/png" sizes="180x180" href="../apple-touch-icon.png">
+<link rel="apple-touch-icon" type="image/png" sizes="120x120" href="../apple-touch-icon-120x120.png">
+<link rel="apple-touch-icon" type="image/png" sizes="76x76" href="../apple-touch-icon-76x76.png">
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+<meta property="og:title" content="Contributing">
+<meta property="og:description" content="ramnog">
+<meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
+<!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
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+    
+
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
+    
+    <a class="navbar-brand me-2" href="../index.html">ramnog</a>
+
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
+
+    
+    <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
+      <span class="navbar-toggler-icon"></span>
+    </button>
+
+    <div id="navbar" class="collapse navbar-collapse ms-3">
+      <ul class="navbar-nav me-auto">
+<li class="nav-item">
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-articles">
+    <h6 class="dropdown-header" data-toc-skip>Overview</h6>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
+    <div class="dropdown-divider"></div>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
+    <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
+    <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
+    <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
+    <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
+    <div class="dropdown-divider"></div>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
+    <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
+    <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
+    <div class="dropdown-divider"></div>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
+    <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
+    <div class="dropdown-divider"></div>
+    <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
+    <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
+  </div>
+</li>
+<li class="active nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
+  </div>
+</li>
+      </ul>
+<form class="form-inline my-2 my-lg-0" role="search">
+        <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
+</form>
+
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
+</div>
+
+    
+  </div>
+</nav><div class="container template-article">
+
+
+
+
+<div class="row">
+  <main id="main" class="col-md-9"><div class="page-header">
+      <img src="../logo.png" class="logo" alt=""><h1>Contributing</h1>
+            
+      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/dev_contribute.Rmd" class="external-link"><code>vignettes/dev_contribute.Rmd</code></a></small>
+      <div class="d-none name"><code>dev_contribute.Rmd</code></div>
+    </div>
+
+    
+    
+<div class="section level2">
+<h2 id="gitflow">Gitflow<a class="anchor" aria-label="anchor" href="#gitflow"></a>
+</h2>
+<p>All packages use <a href="https://www.atlassian.com/git/tutorials/comparing-workflows/gitflow-workflow" class="external-link">Gitflow</a>
+way of working. Please see the linked to resource for details on how to
+work in this style.</p>
+<p>Specifically each package always has the <code>main</code> branch
+that is functioning and deployable.</p>
+<div class="section level4">
+<h4 id="how-to-add-a-feature-bugfix">How to add a feature / bugfix<a class="anchor" aria-label="anchor" href="#how-to-add-a-feature-bugfix"></a>
+</h4>
+<ol style="list-style-type: decimal">
+<li>Create new branch from main, lets say we call it
+<code>feature_A</code>
+</li>
+<li>Develop, commit, and push to <code>feature_A</code>
+</li>
+<li>When you are <a href="#dod">done</a>, make a draft PR from
+<code>feature_A</code> into <code>main</code>. This will trigger the
+CI/CD pipelines and checks to run.</li>
+<li>Check the output of the CI/CD checks and make any requisit changes
+to <code>feature_A</code>
+</li>
+<li>Once the pipeline runs wihout any errors, mark your draft PR as
+ready for review and assign a reviewer</li>
+<li>When the PR is approved, chose the option to <strong>squash and
+merge</strong> your commits. Here you will have the option to summarize
+the changes that your feature/bug fix address.</li>
+<li>Delete the source branch (<code>feature_A</code>)</li>
+</ol>
+</div>
+</div>
+<div class="section level2">
+<h2 id="dod">Definition of done<a class="anchor" aria-label="anchor" href="#dod"></a>
+</h2>
+<p>A feature branch is defined as done and ready for a PR (pull request)
+into main branch only once it has been properly tested. Please see the
+<a href="qc.html">Quality Control</a> vignette for more detailed
+information on what this entails. Briefly, testing consists of:</p>
+<ol style="list-style-type: decimal">
+<li>Unit-tests to test the basic functionality</li>
+<li>Integration testing to ensure all features work together</li>
+<li>Passing the CI/CD</li>
+</ol>
+<p>If you are developing, for example, a new statistical function for
+{chefStats} then it must be checked with unit tests.</p>
+<p>Additionally, all previous unit-tests and integration tests need to
+pass. You can check this by running <code>devtools::test()</code> in the
+respective packages.</p>
+<p><strong>Note:</strong> Integration testing mostly resides in the
+ramnog package, so you will need to run <code>devtools::test()</code>
+there as well</p>
+</div>
+<div class="section level2">
+<h2 id="devops-pre-commit-and-git-actions">DevOps: Pre-commit and Git-actions<a class="anchor" aria-label="anchor" href="#devops-pre-commit-and-git-actions"></a>
+</h2>
+<p>The ramnog ecosystem uses both pre-commit hooks and Git-Actions to
+ensure code quality and consistency.</p>
+<p>Configuration for Pre-commit as well as Git-action workflows are
+hosted in the {ramnog} package and consumed by the other packages.
+Idealy, the DevOps configuration should be hosted in a seperate
+repository, but for now it is in the {ramnog} package.</p>
+<div class="section level4">
+<h4 id="pre-commit">Pre-commit<a class="anchor" aria-label="anchor" href="#pre-commit"></a>
+</h4>
+<p>Pre-commit is a tool that runs checks on the code before it is
+commited. It is configured in the <code>.pre-commit-config.yaml</code>
+file in the root of the repository.</p>
+</div>
+</div>
+  </main><aside class="col-md-3"><nav id="toc"><h2>On this page</h2>
+    </nav></aside>
+</div>
+
+
+
+    <footer><div class="pkgdown-footer-left">
+  <p></p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
+</div>
+
+<div class="pkgdown-footer-right">
+  <p></p>
+<p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.7.</p>
+</div>
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+</div>
+
+  
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+
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diff --git a/articles/dev_devops.html b/articles/dev_devops.html
new file mode 100644
index 0000000..970686e
--- /dev/null
+++ b/articles/dev_devops.html
@@ -0,0 +1,393 @@
+<!DOCTYPE html>
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+<meta property="og:title" content="DevOps">
+<meta property="og:description" content="ramnog">
+<meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
+<!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
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+<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script>
+<![endif]-->
+</head>
+<body>
+    <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
+    
+
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
+    
+    <a class="navbar-brand me-2" href="../index.html">ramnog</a>
+
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
+
+    
+    <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
+      <span class="navbar-toggler-icon"></span>
+    </button>
+
+    <div id="navbar" class="collapse navbar-collapse ms-3">
+      <ul class="navbar-nav me-auto">
+<li class="nav-item">
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-articles">
+    <h6 class="dropdown-header" data-toc-skip>Overview</h6>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
+    <div class="dropdown-divider"></div>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
+    <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
+    <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
+    <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
+    <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
+    <div class="dropdown-divider"></div>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
+    <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
+    <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
+    <div class="dropdown-divider"></div>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
+    <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
+    <div class="dropdown-divider"></div>
+    <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
+    <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
+  </div>
+</li>
+<li class="active nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
+  </div>
+</li>
+      </ul>
+<form class="form-inline my-2 my-lg-0" role="search">
+        <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
+</form>
+
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
+</div>
+
+    
+  </div>
+</nav><div class="container template-article">
+
+
+
+
+<div class="row">
+  <main id="main" class="col-md-9"><div class="page-header">
+      <img src="../logo.png" class="logo" alt=""><h1>DevOps</h1>
+            
+      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/dev_devops.Rmd" class="external-link"><code>vignettes/dev_devops.Rmd</code></a></small>
+      <div class="d-none name"><code>dev_devops.Rmd</code></div>
+    </div>
+
+    
+    
+<p>This vignette describes the <strong>git actions</strong> and
+<strong>pre-commit</strong> hooks that are used to ensure a consistent
+and high-quality codebase.</p>
+<p>These two concepts have different purposes:</p>
+<ul>
+<li><p><strong>github actions</strong> are the heart of the CI/CD
+process for the ramnog ecosystem. On each package they run anytime a
+draft pull-request to the main branch is made. They are run using GitHub
+runners.</p></li>
+<li><p><strong>pre-commit</strong> hooks are run on the developer’s
+local machine on every commit. <strong>NB</strong>. the pre-commit hooks
+are only run if the pre-commit package is installed.</p></li>
+</ul>
+<p>The configuration for both Git-Actions as well as pre-commit hooks is
+stored in the ramnog repository and consumed by the remainder of the
+ecosystem.</p>
+<div class="section level2">
+<h2 id="github-actions">GitHub Actions<a class="anchor" aria-label="anchor" href="#github-actions"></a>
+</h2>
+<p>GitHub Actions are a set of automated workflows that are
+automatically triggered on specific events in a repository.</p>
+<p>In the ramnog ecosystem, the git actions are used to run tests, check
+test coverage, check package dependencies and build the documentation
+site.</p>
+<p><strong>There are two major flows setup for the
+ecosystem.</strong></p>
+<ol style="list-style-type: decimal">
+<li>Check Package 📦
+<ul>
+<li>Check Package Dependencies</li>
+<li>License check</li>
+<li>R-CMD check</li>
+<li>Test (unittest and their coverage)</li>
+<li>Git-leaks (Check for secrets)</li>
+</ul>
+</li>
+<li>Release Package 🚀
+<ul>
+<li>Build and check pkg. tarball</li>
+<li>Build and deploy documentation site
+<ul>
+<li>For Pull-requests into <code>main</code> a new sub-site is created
+for github pages.</li>
+</ul>
+</li>
+<li>Create a release on github
+<ul>
+<li>Is only run if a tag is created on the <code>main</code>
+branch.</li>
+</ul>
+</li>
+</ul>
+</li>
+</ol>
+<div class="section level3">
+<h3 id="system-setup">System setup<a class="anchor" aria-label="anchor" href="#system-setup"></a>
+</h3>
+<p>The workflows are shared across the {ramnog} ecosystem and the flows
+are hosted in the <code>ramnog</code> repository and referenced by the
+{Chef*} repositories.</p>
+<p>The only logic that is stored in the consumer repositories is the
+trigger for the workflows.</p>
+<details><summary><em>chef*/.github/workflows/check-package.yaml</em>
+</summary><div class="sourceCode" id="cb1"><pre class="sourceCode yaml"><code class="sourceCode yaml"><span id="cb1-1"><a href="#cb1-1" tabindex="-1"></a><span class="fu">on</span><span class="kw">:</span></span>
+<span id="cb1-2"><a href="#cb1-2" tabindex="-1"></a><span class="at">  </span><span class="fu">push</span><span class="kw">:</span></span>
+<span id="cb1-3"><a href="#cb1-3" tabindex="-1"></a><span class="at">    </span><span class="fu">branches</span><span class="kw">:</span><span class="at"> </span><span class="kw">[</span><span class="at">main</span><span class="kw">,</span><span class="at"> stage</span><span class="kw">,</span><span class="at"> dev</span><span class="kw">]</span></span>
+<span id="cb1-4"><a href="#cb1-4" tabindex="-1"></a><span class="at">  </span><span class="fu">pull_request</span><span class="kw">:</span></span>
+<span id="cb1-5"><a href="#cb1-5" tabindex="-1"></a><span class="at">    </span><span class="fu">branches</span><span class="kw">:</span><span class="at"> </span><span class="kw">[</span><span class="at">main</span><span class="kw">,</span><span class="at"> stage</span><span class="kw">,</span><span class="at"> dev</span><span class="kw">]</span></span>
+<span id="cb1-6"><a href="#cb1-6" tabindex="-1"></a><span class="at">  </span><span class="fu">workflow_dispatch</span><span class="kw">:</span></span>
+<span id="cb1-7"><a href="#cb1-7" tabindex="-1"></a></span>
+<span id="cb1-8"><a href="#cb1-8" tabindex="-1"></a><span class="fu">name</span><span class="kw">:</span><span class="at"> Check Package 📦</span></span>
+<span id="cb1-9"><a href="#cb1-9" tabindex="-1"></a></span>
+<span id="cb1-10"><a href="#cb1-10" tabindex="-1"></a><span class="fu">jobs</span><span class="kw">:</span></span>
+<span id="cb1-11"><a href="#cb1-11" tabindex="-1"></a><span class="at">  </span><span class="fu">check</span><span class="kw">:</span></span>
+<span id="cb1-12"><a href="#cb1-12" tabindex="-1"></a><span class="at">    </span><span class="fu">name</span><span class="kw">:</span><span class="at"> Checks (from ramnog)</span></span>
+<span id="cb1-13"><a href="#cb1-13" tabindex="-1"></a><span class="at">    </span><span class="fu">uses</span><span class="kw">:</span><span class="at"> hta-pharma/ramnog/.github/workflows/Check-package.yaml@main</span></span></code></pre></div>
+</details><p>The actual workflow is then stored in the <code>ramnog</code>
+repository in the <code>.github/workflows</code> folder. The workflow
+references multiple subflows both local and from external
+repositories.</p>
+<details><summary><em>ramnog/.github/workflows/Check-package.yaml</em>
+</summary><div class="sourceCode" id="cb2"><pre class="sourceCode yaml"><code class="sourceCode yaml"><span id="cb2-1"><a href="#cb2-1" tabindex="-1"></a><span class="fu">on</span><span class="kw">:</span></span>
+<span id="cb2-2"><a href="#cb2-2" tabindex="-1"></a><span class="at">  </span><span class="fu">push</span><span class="kw">:</span></span>
+<span id="cb2-3"><a href="#cb2-3" tabindex="-1"></a><span class="at">    </span><span class="fu">branches</span><span class="kw">:</span><span class="at"> </span><span class="kw">[</span><span class="at">main</span><span class="kw">,</span><span class="at"> stage</span><span class="kw">,</span><span class="at"> dev</span><span class="kw">]</span></span>
+<span id="cb2-4"><a href="#cb2-4" tabindex="-1"></a><span class="at">  </span><span class="fu">pull_request</span><span class="kw">:</span></span>
+<span id="cb2-5"><a href="#cb2-5" tabindex="-1"></a><span class="at">    </span><span class="fu">branches</span><span class="kw">:</span><span class="at"> </span><span class="kw">[</span><span class="at">main</span><span class="kw">,</span><span class="at"> stage</span><span class="kw">,</span><span class="at"> dev</span><span class="kw">]</span></span>
+<span id="cb2-6"><a href="#cb2-6" tabindex="-1"></a><span class="at">  </span><span class="fu">workflow_dispatch</span><span class="kw">:</span></span>
+<span id="cb2-7"><a href="#cb2-7" tabindex="-1"></a><span class="at">  </span><span class="fu">workflow_call</span><span class="kw">:</span></span>
+<span id="cb2-8"><a href="#cb2-8" tabindex="-1"></a></span>
+<span id="cb2-9"><a href="#cb2-9" tabindex="-1"></a><span class="fu">name</span><span class="kw">:</span><span class="at"> Check Package 📦</span></span>
+<span id="cb2-10"><a href="#cb2-10" tabindex="-1"></a></span>
+<span id="cb2-11"><a href="#cb2-11" tabindex="-1"></a><span class="fu">jobs</span><span class="kw">:</span></span>
+<span id="cb2-12"><a href="#cb2-12" tabindex="-1"></a><span class="at">  </span><span class="fu">audit</span><span class="kw">:</span></span>
+<span id="cb2-13"><a href="#cb2-13" tabindex="-1"></a><span class="at">    </span><span class="fu">name</span><span class="kw">:</span><span class="at"> Audit Dependencies 🕵️‍♂️</span></span>
+<span id="cb2-14"><a href="#cb2-14" tabindex="-1"></a><span class="at">    </span><span class="fu">uses</span><span class="kw">:</span><span class="at"> insightsengineering/r.pkg.template/.github/workflows/audit.yaml@main</span></span>
+<span id="cb2-15"><a href="#cb2-15" tabindex="-1"></a></span>
+<span id="cb2-16"><a href="#cb2-16" tabindex="-1"></a><span class="at">  </span><span class="fu">licenses</span><span class="kw">:</span></span>
+<span id="cb2-17"><a href="#cb2-17" tabindex="-1"></a><span class="at">    </span><span class="fu">name</span><span class="kw">:</span><span class="at"> License Check 🃏</span></span>
+<span id="cb2-18"><a href="#cb2-18" tabindex="-1"></a><span class="at">    </span><span class="fu">uses</span><span class="kw">:</span><span class="at"> insightsengineering/r.pkg.template/.github/workflows/licenses.yaml@main</span></span>
+<span id="cb2-19"><a href="#cb2-19" tabindex="-1"></a></span>
+<span id="cb2-20"><a href="#cb2-20" tabindex="-1"></a><span class="at">  </span><span class="fu">check</span><span class="kw">:</span></span>
+<span id="cb2-21"><a href="#cb2-21" tabindex="-1"></a><span class="at">    </span><span class="fu">name</span><span class="kw">:</span><span class="at"> RMD check 📦</span></span>
+<span id="cb2-22"><a href="#cb2-22" tabindex="-1"></a><span class="at">    </span><span class="fu">uses</span><span class="kw">:</span><span class="at"> ./.github/workflows/R-CMD-check.yaml</span></span>
+<span id="cb2-23"><a href="#cb2-23" tabindex="-1"></a></span>
+<span id="cb2-24"><a href="#cb2-24" tabindex="-1"></a><span class="at">  </span><span class="fu">test</span><span class="kw">:</span></span>
+<span id="cb2-25"><a href="#cb2-25" tabindex="-1"></a><span class="at">    </span><span class="fu">name</span><span class="kw">:</span><span class="at"> Test 🧪</span></span>
+<span id="cb2-26"><a href="#cb2-26" tabindex="-1"></a><span class="at">    </span><span class="fu">uses</span><span class="kw">:</span><span class="at"> ./.github/workflows/Test.yaml</span></span>
+<span id="cb2-27"><a href="#cb2-27" tabindex="-1"></a></span>
+<span id="cb2-28"><a href="#cb2-28" tabindex="-1"></a><span class="at">  </span><span class="fu">gitleaks</span><span class="kw">:</span></span>
+<span id="cb2-29"><a href="#cb2-29" tabindex="-1"></a><span class="at">    </span><span class="fu">name</span><span class="kw">:</span><span class="at"> gitleaks 💧</span></span>
+<span id="cb2-30"><a href="#cb2-30" tabindex="-1"></a><span class="at">    </span><span class="fu">uses</span><span class="kw">:</span><span class="at"> insightsengineering/r.pkg.template/.github/workflows/gitleaks.yaml@main</span></span>
+<span id="cb2-31"><a href="#cb2-31" tabindex="-1"></a><span class="at">    </span><span class="fu">with</span><span class="kw">:</span></span>
+<span id="cb2-32"><a href="#cb2-32" tabindex="-1"></a><span class="at">      </span><span class="fu">check-for-pii</span><span class="kw">:</span><span class="at"> </span><span class="ch">false</span><span class="co"> #Currently fails on R packages (not that the test check fails, but that the test fails to run.)</span></span></code></pre></div>
+</details><div class="section level4">
+<h4 id="updating-the-workflows">Updating the workflows<a class="anchor" aria-label="anchor" href="#updating-the-workflows"></a>
+</h4>
+<p>The workflows should be updated in the <code>ramnog</code>
+repository. The workflows in the consumer repositories simply consume
+the workflows from the <code>ramnog</code> repository main branch.</p>
+<p>If possible, keep any updates to workflows within the two main
+workflows (<code>Check Package</code> and <code>Release Package</code>).
+Thus, no updates to the consumer repositories are needed. - Remember
+that you can use conditions inside workflows to run different steps
+based on the event-type.</p>
+<p>Note: When testing an update you may want to create a new branch in
+the <code>ramnog</code> repository and update the workflows in the
+consumer repositories to point to the new branch. This will allow you to
+test the changes without affecting the main branch.</p>
+<details><summary><em>chef*/.github/workflows/check-package.yaml</em> WHILE TESTING
+</summary><div class="sourceCode" id="cb3"><pre class="sourceCode yaml"><code class="sourceCode yaml"><span id="cb3-1"><a href="#cb3-1" tabindex="-1"></a><span class="fu">on</span><span class="kw">:</span></span>
+<span id="cb3-2"><a href="#cb3-2" tabindex="-1"></a><span class="at">  </span><span class="fu">push</span><span class="kw">:</span></span>
+<span id="cb3-3"><a href="#cb3-3" tabindex="-1"></a><span class="at">    </span><span class="fu">branches</span><span class="kw">:</span><span class="at"> </span><span class="kw">[</span><span class="at">main</span><span class="kw">,</span><span class="at"> stage</span><span class="kw">,</span><span class="at"> dev</span><span class="kw">]</span></span>
+<span id="cb3-4"><a href="#cb3-4" tabindex="-1"></a><span class="at">  </span><span class="fu">pull_request</span><span class="kw">:</span></span>
+<span id="cb3-5"><a href="#cb3-5" tabindex="-1"></a><span class="at">    </span><span class="fu">branches</span><span class="kw">:</span><span class="at"> </span><span class="kw">[</span><span class="at">main</span><span class="kw">,</span><span class="at"> stage</span><span class="kw">,</span><span class="at"> dev</span><span class="kw">]</span></span>
+<span id="cb3-6"><a href="#cb3-6" tabindex="-1"></a><span class="at">  </span><span class="fu">workflow_dispatch</span><span class="kw">:</span></span>
+<span id="cb3-7"><a href="#cb3-7" tabindex="-1"></a></span>
+<span id="cb3-8"><a href="#cb3-8" tabindex="-1"></a><span class="fu">name</span><span class="kw">:</span><span class="at"> Check Package 📦</span></span>
+<span id="cb3-9"><a href="#cb3-9" tabindex="-1"></a></span>
+<span id="cb3-10"><a href="#cb3-10" tabindex="-1"></a><span class="fu">jobs</span><span class="kw">:</span></span>
+<span id="cb3-11"><a href="#cb3-11" tabindex="-1"></a><span class="at">  </span><span class="fu">check</span><span class="kw">:</span></span>
+<span id="cb3-12"><a href="#cb3-12" tabindex="-1"></a><span class="at">    </span><span class="fu">name</span><span class="kw">:</span><span class="at"> Checks (from ramnog)</span></span>
+<span id="cb3-13"><a href="#cb3-13" tabindex="-1"></a><span class="at">    </span><span class="fu">uses</span><span class="kw">:</span><span class="at"> hta-pharma/ramnog/.github/workflows/Check-package.yaml@feature/new-workflow</span><span class="co"> # &lt;-- new branch</span></span></code></pre></div>
+</details>
+</div>
+</div>
+</div>
+<div class="section level2">
+<h2 id="pre-commit-hooks">Pre-commit hooks<a class="anchor" aria-label="anchor" href="#pre-commit-hooks"></a>
+</h2>
+<p>Pre-commit hooks is a tool that allows you to run a set of checks on
+your code before you commit it. These are built on the standard git
+hooks, but are easier to manage and share across projects.</p>
+<p>The pre-commit hooks are run on every commit. If the hooks fail, the
+commit will be aborted. The only downside is that you need to install
+the pre-commit package on your machine and activate it for a given
+repository.</p>
+<p>Individual setup of pre-commit hooks is described in the <a href="https://pre-commit.com/" class="external-link">pre-commit documentation</a>.</p>
+<details><summary>
+Quickstart
+</summary><ol style="list-style-type: decimal">
+<li>Install pre-commit in the Individual user space (use pip if pipx is
+not installed)</li>
+</ol>
+<div class="sourceCode" id="cb4"><pre class="sourceCode yaml"><code class="sourceCode yaml"><span id="cb4-1"><a href="#cb4-1" tabindex="-1"></a><span class="at">pipx install pre-commit </span></span></code></pre></div>
+<ol start="2" style="list-style-type: decimal">
+<li>Install the pre-commit hooks in the repository.
+<strong>NOTE:</strong> this needs to be run in the root of the
+repository</li>
+</ol>
+<div class="sourceCode" id="cb5"><pre class="sourceCode yaml"><code class="sourceCode yaml"><span id="cb5-1"><a href="#cb5-1" tabindex="-1"></a><span class="at">pre-commit install </span></span></code></pre></div>
+<ol start="3" style="list-style-type: decimal">
+<li>Run on all files to check it works:</li>
+</ol>
+<div class="sourceCode" id="cb6"><pre class="sourceCode yaml"><code class="sourceCode yaml"><span id="cb6-1"><a href="#cb6-1" tabindex="-1"></a><span class="at">pre-commit run --all-files </span></span></code></pre></div>
+</details><details><summary>
+Troubleshooting: <code>Error: Python not available</code>
+</summary><p>The pre-commit hook requires a python environment. If you do not have
+python installed, you can install it using <code>conda</code> or
+<code>pyenv</code>.</p>
+<p>if you have python3 installed and you get an error that python is not
+available you may need to specify that <code>python3</code> should be
+used. This can be done with either of the following (asumming linux
+environment):</p>
+<div class="sourceCode" id="cb7"><pre class="sourceCode bash"><code class="sourceCode bash"><span id="cb7-1"><a href="#cb7-1" tabindex="-1"></a><span class="co"># Create a symlink for python3 in the python bin</span></span>
+<span id="cb7-2"><a href="#cb7-2" tabindex="-1"></a><span class="fu">sudo</span> ln <span class="at">-s</span> /usr/bin/python3 /usr/bin/python</span>
+<span id="cb7-3"><a href="#cb7-3" tabindex="-1"></a><span class="co"># Install the python-is-python3 package</span></span>
+<span id="cb7-4"><a href="#cb7-4" tabindex="-1"></a><span class="fu">sudo</span> apt-get install python-is-python3</span></code></pre></div>
+</details><div class="section level3">
+<h3 id="usage">Usage<a class="anchor" aria-label="anchor" href="#usage"></a>
+</h3>
+<p>The hooks are run whenever you create a commit. If the hooks fail,
+the commit will be aborted. Some of the hooks will automatically fix the
+issues, others will only report the issues.</p>
+<p>Even if the hooks automatically fix the issues, you will still need
+to add the changes to the commit and commit them again.</p>
+</div>
+<div class="section level3">
+<h3 id="system-setup-1">System setup<a class="anchor" aria-label="anchor" href="#system-setup-1"></a>
+</h3>
+<p>The pre-commits to be run are defined by the
+<code>.pre-commit-config.yaml</code> file in the root of the repository.
+Such a file exists in each of the repositories in the ramnog
+ecosystem.</p>
+<p>For {chef}, {chefStats}, and {chefCriteria} the pre-commit configs
+are identical and points to the <code>org-hook</code> in ramnog.</p>
+<details><summary><em>chef*/.pre-commit-config.yaml</em>
+</summary><div class="sourceCode" id="cb8"><pre class="sourceCode yaml"><code class="sourceCode yaml"><span id="cb8-1"><a href="#cb8-1" tabindex="-1"></a><span class="fu">repos</span><span class="kw">:</span></span>
+<span id="cb8-2"><a href="#cb8-2" tabindex="-1"></a><span class="kw">-</span><span class="at">   </span><span class="fu">repo</span><span class="kw">:</span><span class="at"> https://github.com/hta-pharma/ramnog</span></span>
+<span id="cb8-3"><a href="#cb8-3" tabindex="-1"></a><span class="at">    </span><span class="fu">rev</span><span class="kw">:</span><span class="at"> v0.1.1</span></span>
+<span id="cb8-4"><a href="#cb8-4" tabindex="-1"></a><span class="at">    </span><span class="fu">hooks</span><span class="kw">:</span></span>
+<span id="cb8-5"><a href="#cb8-5" tabindex="-1"></a><span class="at">    </span><span class="kw">-</span><span class="at">   </span><span class="fu">id</span><span class="kw">:</span><span class="at"> org-hook </span></span></code></pre></div>
+</details><p>The <code>org-hook</code> is a custom hook that is defined in the
+ramnog repository. The hook is defined in the <code>hooks</code> folder
+in the ramnog repository.</p>
+<details><summary><em>ramnog/.pre-commit-hooks.yaml</em>
+</summary><div class="sourceCode" id="cb9"><pre class="sourceCode yaml"><code class="sourceCode yaml"><span id="cb9-1"><a href="#cb9-1" tabindex="-1"></a><span class="kw">-</span><span class="at">   </span><span class="fu">id</span><span class="kw">:</span><span class="at"> org-hook</span></span>
+<span id="cb9-2"><a href="#cb9-2" tabindex="-1"></a><span class="at">    </span><span class="fu">name</span><span class="kw">:</span><span class="at"> org-wide hooks</span></span>
+<span id="cb9-3"><a href="#cb9-3" tabindex="-1"></a><span class="at">    </span><span class="fu">language</span><span class="kw">:</span><span class="at"> script</span></span>
+<span id="cb9-4"><a href="#cb9-4" tabindex="-1"></a><span class="at">    </span><span class="fu">entry</span><span class="kw">:</span><span class="at"> ./run-org-hooks</span></span>
+<span id="cb9-5"><a href="#cb9-5" tabindex="-1"></a><span class="at">    </span><span class="fu">verbose</span><span class="kw">:</span><span class="at"> </span><span class="ch">true</span></span>
+<span id="cb9-6"><a href="#cb9-6" tabindex="-1"></a><span class="at">    </span><span class="fu">require_serial</span><span class="kw">:</span><span class="at"> </span><span class="ch">true</span></span></code></pre></div>
+</details><p>The <code>org-hook</code> points to a script that runs pre-commit
+using a standard pre-commit config template. The template is likewise
+stored in the ramnog repository.</p>
+<details><summary><em>ramnog/shared-pre-commit-config.yaml</em>
+</summary><div class="sourceCode" id="cb10"><pre class="sourceCode yaml"><code class="sourceCode yaml"><span id="cb10-1"><a href="#cb10-1" tabindex="-1"></a><span class="fu">repos</span><span class="kw">:</span></span>
+<span id="cb10-2"><a href="#cb10-2" tabindex="-1"></a><span class="kw">-</span><span class="at">   </span><span class="fu">repo</span><span class="kw">:</span><span class="at"> https://github.com/lorenzwalthert/precommit</span></span>
+<span id="cb10-3"><a href="#cb10-3" tabindex="-1"></a><span class="at">    </span><span class="fu">rev</span><span class="kw">:</span><span class="at"> v0.4.0</span></span>
+<span id="cb10-4"><a href="#cb10-4" tabindex="-1"></a><span class="at">    </span><span class="fu">hooks</span><span class="kw">:</span><span class="at"> </span></span>
+<span id="cb10-5"><a href="#cb10-5" tabindex="-1"></a><span class="at">    </span><span class="kw">-</span><span class="at">   </span><span class="fu">id</span><span class="kw">:</span><span class="at"> readme-rmd-rendered</span></span>
+<span id="cb10-6"><a href="#cb10-6" tabindex="-1"></a><span class="at">    </span><span class="kw">-</span><span class="at">   </span><span class="fu">id</span><span class="kw">:</span><span class="at"> parsable-R</span></span>
+<span id="cb10-7"><a href="#cb10-7" tabindex="-1"></a><span class="at">    </span><span class="kw">-</span><span class="at">   </span><span class="fu">id</span><span class="kw">:</span><span class="at"> no-browser-statement</span></span>
+<span id="cb10-8"><a href="#cb10-8" tabindex="-1"></a><span class="at">    (...)</span></span></code></pre></div>
+</details><div class="section level4">
+<h4 id="updating-the-run-hooks">Updating the run hooks:<a class="anchor" aria-label="anchor" href="#updating-the-run-hooks"></a>
+</h4>
+<p>In order to update the hooks, you need to update the
+<code>shared-pre-commit-config.yaml</code> file in the ramnog
+repository. Furthemore, the hooks in the consumer repos (chef*) needs to
+be updated with the version hosted in ramnog.</p>
+<p>You will need to either tag a the ramnog repository following changes
+and update the <code>rev</code> in the
+<code>chef*/.pre-commit-config.yaml</code> files to the new tag.</p>
+<ul>
+<li>Updating the rev in the <code>chef*/.pre-commit-config.yaml</code>
+file will trigger the pre-commit hooks to update the hooks on the next
+commit.</li>
+<li>the command <code>pre-commit auto-update</code> can be used to
+update the consumer hooks.</li>
+</ul>
+<p>Alternatively you can update the consumer <code>rev</code> with the
+latest commit hash in the ramnog repository.</p>
+</div>
+</div>
+</div>
+  </main><aside class="col-md-3"><nav id="toc"><h2>On this page</h2>
+    </nav></aside>
+</div>
+
+
+
+    <footer><div class="pkgdown-footer-left">
+  <p></p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
+</div>
+
+<div class="pkgdown-footer-right">
+  <p></p>
+<p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.7.</p>
+</div>
+
+    </footer>
+</div>
+
+  
+
+  
+
+  </body>
+</html>
diff --git a/articles/ep_overview.html b/articles/ep_overview.html
index e5485ab..979ad52 100644
--- a/articles/ep_overview.html
+++ b/articles/ep_overview.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Endpoint Specification">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Endpoint Specification">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="active nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Endpoint Specification</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/ep_overview.Rmd" class="external-link"><code>vignettes/ep_overview.Rmd</code></a></small>
       <div class="d-none name"><code>ep_overview.Rmd</code></div>
     </div>
 
@@ -310,7 +314,7 @@ <h2 id="components">Components<a class="anchor" aria-label="anchor" href="#compo
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/ep_spec_adam_data.html b/articles/ep_spec_adam_data.html
index 5f33638..2e347c3 100644
--- a/articles/ep_spec_adam_data.html
+++ b/articles/ep_spec_adam_data.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="ADaM Data">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="ADaM Data">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="active nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>ADaM Data</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/ep_spec_adam_data.Rmd" class="external-link"><code>vignettes/ep_spec_adam_data.Rmd</code></a></small>
       <div class="d-none name"><code>ep_spec_adam_data.Rmd</code></div>
     </div>
 
@@ -252,7 +256,7 @@ <h5 id="ex-1-3">Ex 1.3<a class="anchor" aria-label="anchor" href="#ex-1-3"></a>
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/ep_spec_event_def.html b/articles/ep_spec_event_def.html
index 3204300..fd2d578 100644
--- a/articles/ep_spec_event_def.html
+++ b/articles/ep_spec_event_def.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Endpoint Events">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Endpoint Events">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="active nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Endpoint Events</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/ep_spec_event_def.Rmd" class="external-link"><code>vignettes/ep_spec_event_def.Rmd</code></a></small>
       <div class="d-none name"><code>ep_spec_event_def.Rmd</code></div>
     </div>
 
@@ -255,7 +259,7 @@ <h6 id="ex-4-4">Ex 4.4<a class="anchor" aria-label="anchor" href="#ex-4-4"></a>
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/ep_spec_label.html b/articles/ep_spec_label.html
index 5d53ac7..119fa42 100644
--- a/articles/ep_spec_label.html
+++ b/articles/ep_spec_label.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Endpoint Label">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Endpoint Label">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
-</li>
-<li class="active nav-item dropdown">
+<li class="nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Endpoint Label</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/ep_spec_label.Rmd" class="external-link"><code>vignettes/ep_spec_label.Rmd</code></a></small>
       <div class="d-none name"><code>ep_spec_label.Rmd</code></div>
     </div>
 
@@ -210,7 +214,7 @@ <h6 id="ex-6-3">Ex 6.3<a class="anchor" aria-label="anchor" href="#ex-6-3"></a>
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/ep_spec_population_def.html b/articles/ep_spec_population_def.html
index fb6274d..e26c9b8 100644
--- a/articles/ep_spec_population_def.html
+++ b/articles/ep_spec_population_def.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Analysis Population">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Analysis Population">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="active nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Analysis Population</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/ep_spec_population_def.Rmd" class="external-link"><code>vignettes/ep_spec_population_def.Rmd</code></a></small>
       <div class="d-none name"><code>ep_spec_population_def.Rmd</code></div>
     </div>
 
@@ -173,7 +177,7 @@ <h6 id="ex-3-2">Ex 3.2<a class="anchor" aria-label="anchor" href="#ex-3-2"></a>
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/ep_spec_strata_def.html b/articles/ep_spec_strata_def.html
index cd564c7..51014d1 100644
--- a/articles/ep_spec_strata_def.html
+++ b/articles/ep_spec_strata_def.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Strata">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Strata">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="active nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Strata</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/ep_spec_strata_def.Rmd" class="external-link"><code>vignettes/ep_spec_strata_def.Rmd</code></a></small>
       <div class="d-none name"><code>ep_spec_strata_def.Rmd</code></div>
     </div>
 
@@ -185,7 +189,7 @@ <h6 id="ex-5-3">Ex 5.3<a class="anchor" aria-label="anchor" href="#ex-5-3"></a>
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/ep_spec_treatment_arms.html b/articles/ep_spec_treatment_arms.html
index cd90f02..157f647 100644
--- a/articles/ep_spec_treatment_arms.html
+++ b/articles/ep_spec_treatment_arms.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Treatment Arms">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Treatment Arms">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="active nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Treatment Arms</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/ep_spec_treatment_arms.Rmd" class="external-link"><code>vignettes/ep_spec_treatment_arms.Rmd</code></a></small>
       <div class="d-none name"><code>ep_spec_treatment_arms.Rmd</code></div>
     </div>
 
@@ -150,7 +154,7 @@ <h6 id="ex-2-1">Ex 2.1<a class="anchor" aria-label="anchor" href="#ex-2-1"></a>
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/example_ep_spec.html b/articles/example_ep_spec.html
index e8d97bd..39dcd1c 100644
--- a/articles/example_ep_spec.html
+++ b/articles/example_ep_spec.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Endpoint Catalog">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Endpoint Catalog">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="active nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Endpoint Catalog</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/example_ep_spec.Rmd" class="external-link"><code>vignettes/example_ep_spec.Rmd</code></a></small>
       <div class="d-none name"><code>example_ep_spec.Rmd</code></div>
     </div>
 
@@ -591,7 +595,7 @@ <h5 id="case-2-baseline-characteristics-of-analysis-population-categorical-varia
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/index.html b/articles/index.html
index 9e58599..aade8d0 100644
--- a/articles/index.html
+++ b/articles/index.html
@@ -1,16 +1,16 @@
 <!DOCTYPE html>
-<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><title>Articles • ramnog</title><!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="../favicon-16x16.png"><link rel="icon" type="image/png" sizes="32x32" href="../favicon-32x32.png"><link rel="apple-touch-icon" type="image/png" sizes="180x180" href="../apple-touch-icon.png"><link rel="apple-touch-icon" type="image/png" sizes="120x120" href="../apple-touch-icon-120x120.png"><link rel="apple-touch-icon" type="image/png" sizes="76x76" href="../apple-touch-icon-76x76.png"><link rel="apple-touch-icon" type="image/png" sizes="60x60" href="../apple-touch-icon-60x60.png"><script src="../deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet"><script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Articles"><meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
+<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><title>Articles • ramnog</title><!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="../favicon-16x16.png"><link rel="icon" type="image/png" sizes="32x32" href="../favicon-32x32.png"><link rel="apple-touch-icon" type="image/png" sizes="180x180" href="../apple-touch-icon.png"><link rel="apple-touch-icon" type="image/png" sizes="120x120" href="../apple-touch-icon-120x120.png"><link rel="apple-touch-icon" type="image/png" sizes="76x76" href="../apple-touch-icon-76x76.png"><link rel="apple-touch-icon" type="image/png" sizes="60x60" href="../apple-touch-icon-60x60.png"><script src="../deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet"><script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet"><meta property="og:title" content="Articles"><meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
 <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script>
 <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script>
 <![endif]--></head><body>
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -19,48 +19,50 @@
 
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto"><li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul><form class="form-inline my-2 my-lg-0" role="search">
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off"></form>
 
-      <ul class="navbar-nav"></ul></div>
+      <ul class="navbar-nav"><li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul></div>
 
     
   </div>
@@ -71,76 +73,49 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
     </div>
 
     <div class="section ">
-      <h3>Overview</h3>
+      <h3>All vignettes</h3>
       <p class="section-desc"></p>
 
-      <dl><dt><a href="ep_overview.html">Endpoint Specification</a></dt>
+      <dl><dt><a href="debugging.html">Debugging</a></dt>
         <dd>
-      </dd></dl></div>
-    <div class="section ">
-      <h3>Endpoint Population and Outcome Specification</h3>
-      <p class="section-desc"></p>
-
-      <dl><dt><a href="ep_spec_adam_data.html">ADaM Data</a></dt>
+        </dd><dt><a href="dev_contribute.html">Contributing</a></dt>
         <dd>
-        </dd><dt><a href="ep_spec_treatment_arms.html">Treatment Arms</a></dt>
+        </dd><dt><a href="dev_devops.html">DevOps</a></dt>
         <dd>
-        </dd><dt><a href="ep_spec_population_def.html">Analysis Population</a></dt>
+        </dd><dt><a href="ep_overview.html">Endpoint Specification</a></dt>
         <dd>
-        </dd><dt><a href="ep_spec_event_def.html">Endpoint Events</a></dt>
+        </dd><dt><a href="ep_spec_adam_data.html">ADaM Data</a></dt>
         <dd>
-        </dd><dt><a href="ep_spec_strata_def.html">Strata</a></dt>
+        </dd><dt><a href="ep_spec_event_def.html">Endpoint Events</a></dt>
         <dd>
         </dd><dt><a href="ep_spec_label.html">Endpoint Label</a></dt>
         <dd>
-      </dd></dl></div>
-    <div class="section ">
-      <h3>Endpoint Statistics</h3>
-      <p class="section-desc"></p>
-
-      <dl><dt><a href="methods_criteria.html">Criteria Methods</a></dt>
+        </dd><dt><a href="ep_spec_population_def.html">Analysis Population</a></dt>
         <dd>
-        </dd><dt><a href="methods_stat.html">Statistical Methods</a></dt>
+        </dd><dt><a href="ep_spec_strata_def.html">Strata</a></dt>
         <dd>
-      </dd></dl></div>
-    <div class="section ">
-      <h3>Endpoint Results</h3>
-      <p class="section-desc"></p>
-
-      <dl><dt><a href="results_datamodel.html">Result Data Model</a></dt>
+        </dd><dt><a href="ep_spec_treatment_arms.html">Treatment Arms</a></dt>
         <dd>
-        </dd><dt><a href="results_datamodel2tfl.html">Mapping Results to TFLs</a></dt>
+        </dd><dt><a href="example_ep_spec.html">Endpoint Catalog</a></dt>
         <dd>
-      </dd></dl></div>
-    <div class="section ">
-      <h3>Endpoint Examples</h3>
-      <p class="section-desc"></p>
-
-      <dl><dt><a href="example_ep_spec.html">Endpoint Catalog</a></dt>
+        </dd><dt><a href="methods_criteria.html">Criteria Methods</a></dt>
         <dd>
-      </dd></dl></div>
-    <div class="section ">
-      <h3>Debugging</h3>
-      <p class="section-desc"></p>
-
-      <dl><dt><a href="debugging.html">Debugging</a></dt>
+        </dd><dt><a href="methods_stat.html">Statistical Methods</a></dt>
         <dd>
-      </dd></dl></div>
-    <div class="section ">
-      <h3>Development</h3>
-      <p class="section-desc"></p>
-
-      <dl><dt><a href="dev_git.html">Contributing</a></dt>
+        </dd><dt><a href="qc.html">Quality control for ramnog ecosystem</a></dt>
+        <dd>
+        </dd><dt><a href="ramnog.html">Quick Start</a></dt>
         <dd>
-        </dd><dt><a href="validation.html">Quality control for ramnog ecosystem</a></dt>
+        </dd><dt><a href="results_datamodel.html">Result Data Model</a></dt>
+        <dd>
+        </dd><dt><a href="results_datamodel2tfl.html">Mapping Results to TFLs</a></dt>
         <dd>
       </dd></dl></div>
-  </main><aside class="col-md-3"><nav id="toc"><h2>On this page</h2>
-    </nav></aside></div>
+  </main></div>
 
 
     <footer><div class="pkgdown-footer-left">
-  <p></p><p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+  <p></p><p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/methods_criteria.html b/articles/methods_criteria.html
index 24f017d..c47e9fe 100644
--- a/articles/methods_criteria.html
+++ b/articles/methods_criteria.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
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-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Criteria Methods">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Criteria Methods">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="active nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Criteria Methods</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/methods_criteria.Rmd" class="external-link"><code>vignettes/methods_criteria.Rmd</code></a></small>
       <div class="d-none name"><code>methods_criteria.Rmd</code></div>
     </div>
 
@@ -724,7 +728,7 @@ <h3 id="applying-criteria-functions">Applying criteria functions<a class="anchor
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/methods_stat.html b/articles/methods_stat.html
index 5a3697a..46247a2 100644
--- a/articles/methods_stat.html
+++ b/articles/methods_stat.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Statistical Methods">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Statistical Methods">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="active nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Statistical Methods</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/methods_stat.Rmd" class="external-link"><code>vignettes/methods_stat.Rmd</code></a></small>
       <div class="d-none name"><code>methods_stat.Rmd</code></div>
     </div>
 
@@ -130,16 +134,16 @@ <h2 id="statistical-method-types">Statistical method types<a class="anchor" aria
 Table 1
 </caption>
 <thead><tr>
-<th style="text-align:left;background-color: lightblue !important;">
+<th style="text-align:left;color: white !important;background-color: rgba(44, 62, 80, 255) !important;">
 Name
 </th>
-<th style="text-align:left;background-color: lightblue !important;">
+<th style="text-align:left;color: white !important;background-color: rgba(44, 62, 80, 255) !important;">
 Description
 </th>
-<th style="text-align:left;background-color: lightblue !important;">
+<th style="text-align:left;color: white !important;background-color: rgba(44, 62, 80, 255) !important;">
 Example function
 </th>
-<th style="text-align:left;background-color: lightblue !important;">
+<th style="text-align:left;color: white !important;background-color: rgba(44, 62, 80, 255) !important;">
 Example application
 </th>
 </tr></thead>
@@ -257,7 +261,7 @@ <h2 id="project-specific-statistical-functions">Project-specific statistical fun
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/qc.html b/articles/qc.html
new file mode 100644
index 0000000..1f9a851
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@@ -0,0 +1,352 @@
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+
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+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
+    <div class="dropdown-divider"></div>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
+    <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
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+
+
+
+<div class="row">
+  <main id="main" class="col-md-9"><div class="page-header">
+      <img src="../logo.png" class="logo" alt=""><h1>Quality control for ramnog ecosystem</h1>
+            
+      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/qc.Rmd" class="external-link"><code>vignettes/qc.Rmd</code></a></small>
+      <div class="d-none name"><code>qc.Rmd</code></div>
+    </div>
+
+    
+    
+<p>The validity of the {ramnog} framework is ensured on several
+levels:</p>
+<ul>
+<li>Unit test individual functions/modules in all packages</li>
+<li>Integration/end-to-end testing to ensure the interactions between
+individual functions/modules (that have been unit tested) are as
+expected</li>
+<li>CI/CD to ensure changes are properly tested and deployed to the
+users</li>
+</ul>
+<div class="section level2">
+<h2 id="unit-testing">Unit testing<a class="anchor" aria-label="anchor" href="#unit-testing"></a>
+</h2>
+<p>Each package contains the unit tests for the functionality that
+package is responsible for. This means, for example, it is the
+responsibility of the unit-tests in {chefStats} to ensure that the
+statistical functions written in chefStats produce the result they are
+supposed to produce.</p>
+</div>
+<div class="section level2">
+<h2 id="integration-testing">Integration testing<a class="anchor" aria-label="anchor" href="#integration-testing"></a>
+</h2>
+<p>Integration testing verifies the framework produces the expected
+results</p>
+<p>The integration testing is done via the {testthat} framework, and are
+essentially unit-tests that cover many different units</p>
+<p>The goal is to compare the results of an analysis run via ramnog with
+the expected results done from a manual calculation of the same
+analysis.</p>
+<p>For example, below is the unit test to ensure the results of an
+endpoint definition defined and run via chef match those calculated
+manually</p>
+<details><summary>
+Example of integration test using {testthat} framework
+</summary><div class="sourceCode" id="cb1"><pre class="downlit sourceCode r">
+<code class="sourceCode R"><span><span class="fu">testthat</span><span class="fu">::</span><span class="fu"><a href="https://testthat.r-lib.org/reference/test_that.html" class="external-link">test_that</a></span><span class="op">(</span><span class="st">"Valide stats when one strata level is not found"</span>,</span>
+<span>          <span class="op">{</span></span>
+<span>            <span class="co"># SETUP -------------------------------------------------------------------</span></span>
+<span>            <span class="fu">testr</span><span class="fu">::</span><span class="fu"><a href="https://rdrr.io/pkg/testr/man/create_local_project.html" class="external-link">create_local_project</a></span><span class="op">(</span><span class="op">)</span></span>
+<span>            <span class="va">mk_adae</span> <span class="op">&lt;-</span> <span class="kw">function</span><span class="op">(</span><span class="va">study_metadata</span><span class="op">)</span> <span class="op">{</span></span>
+<span>              <span class="va">adsl</span> <span class="op">&lt;-</span> <span class="fu">pharmaverseadam</span><span class="fu">::</span><span class="va"><a href="https://pharmaverse.github.io/pharmaverseadam/main/reference/adsl.html" class="external-link">adsl</a></span> <span class="op">|&gt;</span> <span class="fu">data.table</span><span class="fu">::</span><span class="fu"><a href="https://rdatatable.gitlab.io/data.table/reference/setDT.html" class="external-link">setDT</a></span><span class="op">(</span><span class="op">)</span></span>
+<span>              <span class="va">adae</span> <span class="op">&lt;-</span> <span class="fu">pharmaverseadam</span><span class="fu">::</span><span class="va"><a href="https://pharmaverse.github.io/pharmaverseadam/main/reference/adae.html" class="external-link">adae</a></span> <span class="op">|&gt;</span> <span class="fu">data.table</span><span class="fu">::</span><span class="fu"><a href="https://rdatatable.gitlab.io/data.table/reference/setDT.html" class="external-link">setDT</a></span><span class="op">(</span><span class="op">)</span></span>
+<span>              <span class="va">adae_out</span> <span class="op">&lt;-</span></span>
+<span>                <span class="fu"><a href="https://rdrr.io/r/base/merge.html" class="external-link">merge</a></span><span class="op">(</span><span class="va">adsl</span>, <span class="va">adae</span><span class="op">[</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/sets.html" class="external-link">setdiff</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">adae</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">adsl</span><span class="op">)</span><span class="op">)</span>, <span class="st">"USUBJID"</span><span class="op">)</span>, with <span class="op">=</span></span>
+<span>                                   <span class="cn">F</span><span class="op">]</span>, by <span class="op">=</span> <span class="st">"USUBJID"</span>, all <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span>
+<span>              <span class="va">adae_out</span><span class="op">[</span><span class="va">TRT01A</span> <span class="op"><a href="https://rdrr.io/r/base/match.html" class="external-link">%in%</a></span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">'Placebo'</span>, <span class="st">'Xanomeline High Dose'</span><span class="op">)</span>,<span class="op">]</span></span>
+<span>            <span class="op">}</span></span>
+<span>            <span class="va">mk_ep_def</span> <span class="op">&lt;-</span> <span class="kw">function</span><span class="op">(</span><span class="op">)</span> <span class="op">{</span></span>
+<span>              <span class="fu">chef</span><span class="fu">::</span><span class="fu"><a href="https://hta-pharma.github.io/chef/reference/mk_endpoint_str.html" class="external-link">mk_endpoint_str</a></span><span class="op">(</span></span>
+<span>                study_metadata <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="op">)</span>,</span>
+<span>                pop_var <span class="op">=</span> <span class="st">"SAFFL"</span>,</span>
+<span>                pop_value <span class="op">=</span> <span class="st">"Y"</span>,</span>
+<span>                treatment_var <span class="op">=</span> <span class="st">"TRT01A"</span>,</span>
+<span>                treatment_refval <span class="op">=</span> <span class="st">"Xanomeline High Dose"</span>,</span>
+<span>                stratify_by <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="st">"SEX"</span><span class="op">)</span><span class="op">)</span>,</span>
+<span>                data_prepare <span class="op">=</span> <span class="va">mk_adae</span>,</span>
+<span>                endpoint_label <span class="op">=</span> <span class="st">"A"</span>,</span>
+<span>                custom_pop_filter <span class="op">=</span> <span class="st">"SEX == 'F'"</span>,</span>
+<span>                group_by <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span>AESEV <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="op">)</span><span class="op">)</span><span class="op">)</span>,</span>
+<span>                stat_by_strata_by_trt <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span></span>
+<span>                  <span class="st">"N"</span> <span class="op">=</span> <span class="fu">chefStats</span><span class="fu">::</span><span class="va"><a href="https://hta-pharma.github.io/chefStats/reference/n_subj.html" class="external-link">n_subj</a></span>,</span>
+<span>                  <span class="st">"E"</span> <span class="op">=</span> <span class="fu">chefStats</span><span class="fu">::</span><span class="va"><a href="https://hta-pharma.github.io/chefStats/reference/n_event.html" class="external-link">n_event</a></span>,</span>
+<span>                  <span class="st">"N subj E"</span> <span class="op">=</span> <span class="fu">chefStats</span><span class="fu">::</span><span class="va"><a href="https://hta-pharma.github.io/chefStats/reference/n_subj_event.html" class="external-link">n_subj_event</a></span></span>
+<span>                <span class="op">)</span>,</span>
+<span>                stat_by_strata_across_trt <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"RR"</span> <span class="op">=</span> <span class="fu">chefStats</span><span class="fu">::</span><span class="va"><a href="https://hta-pharma.github.io/chefStats/reference/RR.html" class="external-link">RR</a></span>,</span>
+<span>                                                 <span class="st">"OR"</span> <span class="op">=</span> <span class="fu">chefStats</span><span class="fu">::</span><span class="va"><a href="https://hta-pharma.github.io/chefStats/reference/OR.html" class="external-link">OR</a></span><span class="op">)</span>,</span>
+<span>                stat_across_strata_across_trt <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="st">"P-interaction"</span> <span class="op">=</span> <span class="fu">chefStats</span><span class="fu">::</span><span class="va"><a href="https://hta-pharma.github.io/chefStats/reference/p_val_interaction.html" class="external-link">p_val_interaction</a></span><span class="op">)</span></span>
+<span>              <span class="op">)</span></span>
+<span>            <span class="op">}</span></span>
+<span></span>
+<span>            <span class="fu">chef</span><span class="fu">::</span><span class="fu"><a href="https://hta-pharma.github.io/chef/reference/use_chef.html" class="external-link">use_chef</a></span><span class="op">(</span></span>
+<span>              pipeline_dir <span class="op">=</span> <span class="st">"pipeline"</span>,</span>
+<span>              r_functions_dir <span class="op">=</span> <span class="st">"R/"</span>,</span>
+<span>              pipeline_id <span class="op">=</span> <span class="st">"01"</span>,</span>
+<span>              mk_endpoint_def_fn <span class="op">=</span> <span class="va">mk_ep_def</span>,</span>
+<span>              mk_adam_fn <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/list.html" class="external-link">list</a></span><span class="op">(</span><span class="va">mk_adae</span><span class="op">)</span></span>
+<span>            <span class="op">)</span></span>
+<span>            <span class="co"># ACT ---------------------------------------------------------------------</span></span>
+<span>            <span class="fu">targets</span><span class="fu">::</span><span class="fu"><a href="https://docs.ropensci.org/targets/reference/tar_make.html" class="external-link">tar_make</a></span><span class="op">(</span><span class="op">)</span></span>
+<span>            <span class="fu">targets</span><span class="fu">::</span><span class="fu"><a href="https://docs.ropensci.org/targets/reference/tar_load.html" class="external-link">tar_load</a></span><span class="op">(</span><span class="va">ep_stat</span><span class="op">)</span></span>
+<span>            <span class="co"># EXPECT ------------------------------------------------------------------</span></span>
+<span>            <span class="co"># Manually calculated expected results</span></span>
+<span>            <span class="va">x</span> <span class="op">&lt;-</span> <span class="fu">mk_adae</span><span class="op">(</span>study_metadata <span class="op">=</span> <span class="cn">NULL</span><span class="op">)</span></span>
+<span>            <span class="co"># Relative Risk</span></span>
+<span>            <span class="va">actual</span> <span class="op">&lt;-</span></span>
+<span>              <span class="va">ep_stat</span><span class="op">[</span><span class="va">endpoint_group_filter</span> <span class="op">==</span> <span class="st">"AESEV == \"SEVERE\""</span> <span class="op">&amp;</span></span>
+<span>                        <span class="va">fn_name</span> <span class="op">==</span> <span class="st">"RR"</span> <span class="op">&amp;</span></span>
+<span>                        <span class="va">stat_filter</span> <span class="op">==</span> <span class="st">"SEX == \"F\""</span> <span class="op">&amp;</span> <span class="va">stat_result_label</span> <span class="op">==</span> <span class="st">"RR"</span>, <span class="va">stat_result_value</span><span class="op">]</span></span>
+<span>            <span class="va">x1</span> <span class="op">&lt;-</span> <span class="va">x</span><span class="op">[</span><span class="va">SEX</span> <span class="op">==</span> <span class="st">"F"</span> <span class="op">&amp;</span> <span class="va">SAFFL</span> <span class="op">==</span> <span class="st">"Y"</span><span class="op">]</span></span>
+<span>            <span class="va">x1</span><span class="op">[</span>, <span class="va">event</span> <span class="op">:=</span> <span class="cn">FALSE</span><span class="op">]</span></span>
+<span>            <span class="va">x1</span><span class="op">[</span><span class="va">AESEV</span> <span class="op">==</span> <span class="st">"SEVERE"</span>, <span class="va">event</span> <span class="op">:=</span> <span class="cn">TRUE</span><span class="op">]</span> <span class="op">|&gt;</span> <span class="fu">data.table</span><span class="fu">::</span><span class="fu"><a href="https://rdatatable.gitlab.io/data.table/reference/setorder.html" class="external-link">setorder</a></span><span class="op">(</span><span class="op">-</span><span class="va">event</span><span class="op">)</span></span>
+<span>            <span class="va">x1_unique</span> <span class="op">&lt;-</span></span>
+<span>              <span class="fu"><a href="https://rdrr.io/r/base/unique.html" class="external-link">unique</a></span><span class="op">(</span><span class="va">x1</span>, by <span class="op">=</span> <span class="st">"USUBJID"</span>, fromLast <span class="op">=</span> <span class="cn">FALSE</span><span class="op">)</span></span>
+<span>            <span class="va">two_by_two</span> <span class="op">&lt;-</span></span>
+<span>              <span class="va">x1_unique</span><span class="op">[</span>, <span class="va">.N</span>, by <span class="op">=</span> <span class="fu">.</span><span class="op">(</span><span class="va">TRT01A</span>, <span class="va">event</span><span class="op">)</span><span class="op">]</span><span class="op">[</span><span class="fu"><a href="https://rdrr.io/r/base/order.html" class="external-link">order</a></span><span class="op">(</span><span class="va">TRT01A</span>, <span class="va">event</span><span class="op">)</span><span class="op">]</span></span>
+<span>            </span>
+<span>            <span class="co"># Outcome, exposed</span></span>
+<span>            <span class="va">a</span> <span class="op">&lt;-</span></span>
+<span>              <span class="va">two_by_two</span><span class="op">[</span><span class="va">TRT01A</span> <span class="op">==</span> <span class="st">"Xanomeline High Dose"</span> <span class="op">&amp;</span></span>
+<span>                           <span class="op">(</span><span class="va">event</span><span class="op">)</span>, <span class="va">N</span><span class="op">]</span> </span>
+<span>            </span>
+<span>            <span class="co"># No outcome, exposed</span></span>
+<span>            <span class="va">b</span> <span class="op">&lt;-</span></span>
+<span>              <span class="va">two_by_two</span><span class="op">[</span><span class="va">TRT01A</span> <span class="op">==</span> <span class="st">"Xanomeline High Dose"</span> <span class="op">&amp;</span></span>
+<span>                           <span class="op">!</span><span class="op">(</span><span class="va">event</span><span class="op">)</span>, <span class="va">N</span><span class="op">]</span> </span>
+<span>             </span>
+<span>            <span class="co"># Outcome, not exposed</span></span>
+<span>            <span class="va">c</span> <span class="op">&lt;-</span></span>
+<span>              <span class="va">two_by_two</span><span class="op">[</span><span class="va">TRT01A</span> <span class="op">==</span> <span class="st">"Placebo"</span> <span class="op">&amp;</span></span>
+<span>                           <span class="op">(</span><span class="va">event</span><span class="op">)</span>, <span class="va">N</span><span class="op">]</span></span>
+<span>            </span>
+<span>            <span class="co"># No outcome, not exposed</span></span>
+<span>            <span class="va">d</span> <span class="op">&lt;-</span></span>
+<span>              <span class="va">two_by_two</span><span class="op">[</span><span class="va">TRT01A</span> <span class="op">==</span> <span class="st">"Placebo"</span> <span class="op">&amp;</span></span>
+<span>                           <span class="op">!</span><span class="op">(</span><span class="va">event</span><span class="op">)</span>, <span class="va">N</span><span class="op">]</span> </span>
+<span>            </span>
+<span>            <span class="va">expected</span> <span class="op">&lt;-</span> <span class="op">(</span><span class="va">a</span> <span class="op">/</span> <span class="fu"><a href="https://rdrr.io/r/base/sum.html" class="external-link">sum</a></span><span class="op">(</span><span class="va">a</span>, <span class="va">b</span><span class="op">)</span><span class="op">)</span> <span class="op">/</span> <span class="op">(</span><span class="va">c</span> <span class="op">/</span> <span class="fu"><a href="https://rdrr.io/r/base/sum.html" class="external-link">sum</a></span><span class="op">(</span><span class="va">c</span>, <span class="va">d</span><span class="op">)</span><span class="op">)</span></span>
+<span>            <span class="fu">expect_identical</span><span class="op">(</span><span class="va">actual</span>, <span class="va">expected</span><span class="op">)</span></span>
+<span></span>
+<span>            <span class="co"># Number of Events</span></span>
+<span>            <span class="va">actual</span> <span class="op">&lt;-</span></span>
+<span>              <span class="va">ep_stat</span><span class="op">[</span><span class="va">endpoint_group_filter</span> <span class="op">==</span> <span class="st">"AESEV == \"SEVERE\""</span> <span class="op">&amp;</span></span>
+<span>                        <span class="va">fn_name</span> <span class="op">==</span> <span class="st">"E"</span> <span class="op">&amp;</span></span>
+<span>                        <span class="va">strata_var</span> <span class="op">==</span> <span class="st">"SEX"</span><span class="op">]</span></span>
+<span>            <span class="va">expected</span> <span class="op">&lt;-</span></span>
+<span>              <span class="va">x1</span><span class="op">[</span><span class="op">(</span><span class="va">event</span><span class="op">)</span>, <span class="va">.N</span>, by <span class="op">=</span> <span class="fu">.</span><span class="op">(</span><span class="va">TRT01A</span><span class="op">)</span><span class="op">]</span><span class="op">[</span><span class="fu"><a href="https://rdrr.io/r/base/order.html" class="external-link">order</a></span><span class="op">(</span><span class="va">TRT01A</span><span class="op">)</span><span class="op">]</span><span class="op">[</span>, <span class="fu"><a href="https://rdrr.io/r/base/double.html" class="external-link">as.double</a></span><span class="op">(</span><span class="va">N</span><span class="op">)</span><span class="op">]</span></span>
+<span>            <span class="fu">expect_identical</span><span class="op">(</span><span class="va">actual</span><span class="op">$</span><span class="va">stat_result_value</span>, <span class="va">expected</span><span class="op">)</span></span>
+<span>          <span class="op">}</span><span class="op">)</span></span>
+<span><span class="co">#&gt; v Setting active project to '/tmp/RtmpmDDHCp/testproj1c7a4756a670'</span></span>
+<span><span class="co">#&gt; v Writing 'R/packages.R'</span></span>
+<span><span class="co">#&gt; v Writing 'pipeline/pipeline_01.R'</span></span>
+<span><span class="co">#&gt; * Edit 'pipeline/pipeline_01.R'</span></span>
+<span><span class="co">#&gt; * Edit 'R/mk_adae.R'</span></span>
+<span><span class="co">#&gt; i Renaming "mk_ep_def" to "mk_endpoint_def.R"</span></span>
+<span><span class="co">#&gt; </span></span>
+<span><span class="co">#&gt; * Edit 'R/mk_endpoint_def.R'</span></span>
+<span><span class="co">#&gt; Loading required package: targets</span></span>
+<span><span class="co">#&gt; ▶ dispatched target ep</span></span>
+<span><span class="co">#&gt; ● completed target ep [0.03 seconds]</span></span>
+<span><span class="co">#&gt; ▶ dispatched target ep_id</span></span>
+<span><span class="co">#&gt; ● completed target ep_id [0.009 seconds]</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_fn_map_a9f94f07</span></span>
+<span><span class="co">#&gt; ● completed branch ep_fn_map_a9f94f07 [0.032 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_fn_map</span></span>
+<span><span class="co">#&gt; ▶ dispatched target user_def_fn</span></span>
+<span><span class="co">#&gt; ● completed target user_def_fn [0.003 seconds]</span></span>
+<span><span class="co">#&gt; ▶ dispatched target study_data</span></span>
+<span><span class="co">#&gt; ● completed target study_data [0.038 seconds]</span></span>
+<span><span class="co">#&gt; ▶ dispatched target fn_map_tibble</span></span>
+<span><span class="co">#&gt; ● completed target fn_map_tibble [0.005 seconds]</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_and_data_a9f94f07</span></span>
+<span><span class="co">#&gt; ● completed branch ep_and_data_a9f94f07 [0.008 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_and_data</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch fn_map_f5f06580</span></span>
+<span><span class="co">#&gt; ● completed branch fn_map_f5f06580 [0.001 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern fn_map</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch analysis_data_container_5d792ea5</span></span>
+<span><span class="co">#&gt; ● completed branch analysis_data_container_5d792ea5 [0 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern analysis_data_container</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_with_data_key_5d792ea5</span></span>
+<span><span class="co">#&gt; ● completed branch ep_with_data_key_5d792ea5 [0 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_with_data_key</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_expanded_0ccac0a6</span></span>
+<span><span class="co">#&gt; ● completed branch ep_expanded_0ccac0a6 [0.035 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_expanded</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_event_index_74b91187</span></span>
+<span><span class="co">#&gt; ● completed branch ep_event_index_74b91187 [0.009 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_event_index</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_crit_endpoint_fafa2a2e</span></span>
+<span><span class="co">#&gt; ● completed branch ep_crit_endpoint_fafa2a2e [0.003 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_crit_endpoint</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_crit_by_strata_by_trt_8436637b</span></span>
+<span><span class="co">#&gt; ● completed branch ep_crit_by_strata_by_trt_8436637b [0.009 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_crit_by_strata_by_trt</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_crit_by_strata_across_trt_821fa7bd</span></span>
+<span><span class="co">#&gt; ● completed branch ep_crit_by_strata_across_trt_821fa7bd [0.004 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_crit_by_strata_across_trt</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_prep_by_strata_across_trt_71db754a</span></span>
+<span><span class="co">#&gt; ● completed branch ep_prep_by_strata_across_trt_71db754a [0.038 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_prep_by_strata_across_trt</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_prep_across_strata_across_trt_71db754a</span></span>
+<span><span class="co">#&gt; ● completed branch ep_prep_across_strata_across_trt_71db754a [0.016 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_prep_across_strata_across_trt</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_prep_by_strata_by_trt_71db754a</span></span>
+<span><span class="co">#&gt; ● completed branch ep_prep_by_strata_by_trt_71db754a [0.064 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_prep_by_strata_by_trt</span></span>
+<span><span class="co">#&gt; ▶ dispatched target ep_rejected</span></span>
+<span><span class="co">#&gt; ● completed target ep_rejected [0.001 seconds]</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_stat_by_strata_across_trt_c1669b51</span></span>
+<span><span class="co">#&gt; ● completed branch ep_stat_by_strata_across_trt_c1669b51 [0.124 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_stat_by_strata_across_trt</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_stat_across_strata_across_trt_81193129</span></span>
+<span><span class="co">#&gt; ● completed branch ep_stat_across_strata_across_trt_81193129 [0.032 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_stat_across_strata_across_trt</span></span>
+<span><span class="co">#&gt; ▶ dispatched branch ep_stat_by_strata_by_trt_2f3f8ab5</span></span>
+<span><span class="co">#&gt; ● completed branch ep_stat_by_strata_by_trt_2f3f8ab5 [0.045 seconds]</span></span>
+<span><span class="co">#&gt; ● completed pattern ep_stat_by_strata_by_trt</span></span>
+<span><span class="co">#&gt; ▶ dispatched target ep_stat_nested</span></span>
+<span><span class="co">#&gt; ● completed target ep_stat_nested [0 seconds]</span></span>
+<span><span class="co">#&gt; ▶ dispatched target ep_stat</span></span>
+<span><span class="co">#&gt; ● completed target ep_stat [0.013 seconds]</span></span>
+<span><span class="co">#&gt; ▶ ended pipeline [0.762 seconds]</span></span>
+<span><span class="co">#&gt; v Restoring original working directory: '/home/runner/work/ramnog/ramnog/vignettes/'</span></span>
+<span><span class="co">#&gt; v Setting active project to '&lt;no active project&gt;'</span></span>
+<span><span class="co">#&gt; v Deleting temporary project: '/tmp/RtmpmDDHCp/testproj1c7a4756a670/'</span></span>
+<span><span class="co">#&gt; Test passed</span></span></code></pre></div>
+</details>
+</div>
+<div class="section level2">
+<h2 id="cicd">CI/CD<a class="anchor" aria-label="anchor" href="#cicd"></a>
+</h2>
+<p>Please see the <a href="dev_devops.html">DevOps</a> vignette for
+details on the CI/CD infrastructure.</p>
+</div>
+  </main><aside class="col-md-3"><nav id="toc"><h2>On this page</h2>
+    </nav></aside>
+</div>
+
+
+
+    <footer><div class="pkgdown-footer-left">
+  <p></p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
+</div>
+
+<div class="pkgdown-footer-right">
+  <p></p>
+<p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.7.</p>
+</div>
+
+    </footer>
+</div>
+
+  
+
+  
+
+  </body>
+</html>
diff --git a/articles/ramnog.html b/articles/ramnog.html
index bdddb03..e8cdf9b 100644
--- a/articles/ramnog.html
+++ b/articles/ramnog.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Quick Start">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Quick Start">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="active nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,17 +105,24 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Quick Start</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/ramnog.Rmd" class="external-link"><code>vignettes/ramnog.Rmd</code></a></small>
       <div class="d-none name"><code>ramnog.Rmd</code></div>
     </div>
 
     
     
-<p>Here we start with an empty R project and walk through a full working
-example analysis. Our goal for this example analysis is to report the
-number of subjects experiencing a mild adverse event in each treatment
-arm stratified by a custom age grouping. For this example we use the
-ADAE dataset provided in the {pharmaverseadam} package.</p>
+<p>In this vignette we start with an empty R project and walk through a
+full working example analysis.</p>
+<p>Our goal for this example analysis is to report the number of
+subjects experiencing a mild adverse event in each treatment arm
+stratified by a custom age grouping. For this example we use the ADAE
+dataset provided in the {pharmaverseadam} package. To run this example
+you will need the following packages installed:</p>
+<ul>
+<li><a href="https://github.com/hta-pharma/chef" class="external-link">chef</a></li>
+<li><a href="https://github.com/hta-pharma/chefStats" class="external-link">chefStats</a></li>
+<li><a href="https://github.com/pharmaverse/pharmaverseadam" class="external-link">pharmaverseadam</a></li>
+</ul>
 <p>The outline of the workflow will be:</p>
 <ol style="list-style-type: decimal">
 <li>Set up our project infrastructure by running
@@ -160,10 +171,10 @@ <h2 id="set-up-project-infrastructure">1. Set up project infrastructure<a class=
 <p>{chef} has a convenience function to set up this infrastructure for
 you:</p>
 <div class="sourceCode" id="cb2"><pre class="downlit sourceCode r">
-<code class="sourceCode R"><span>    <span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">library</a></span><span class="op">(</span><span class="va"><a href="https://hta-pharma.github.io/chef/" class="external-link">chef</a></span><span class="op">)</span></span>
-<span>    <span class="fu">chef</span><span class="fu">::</span><span class="fu"><a href="https://hta-pharma.github.io/chef/reference/use_chef.html" class="external-link">use_chef</a></span><span class="op">(</span></span>
-<span>      pipeline_id <span class="op">=</span> <span class="st">"01"</span></span>
-<span>    <span class="op">)</span></span></code></pre></div>
+<code class="sourceCode R"><span><span class="kw"><a href="https://rdrr.io/r/base/library.html" class="external-link">library</a></span><span class="op">(</span><span class="va"><a href="https://hta-pharma.github.io/chef/" class="external-link">chef</a></span><span class="op">)</span></span>
+<span><span class="fu">chef</span><span class="fu">::</span><span class="fu"><a href="https://hta-pharma.github.io/chef/reference/use_chef.html" class="external-link">use_chef</a></span><span class="op">(</span></span>
+<span>  pipeline_id <span class="op">=</span> <span class="st">"01"</span></span>
+<span><span class="op">)</span></span></code></pre></div>
 <p>This sets up the following file structure:</p>
 <p>For now we need to know what the file in <code>R/</code> do. For the
 <code>_targets.yml</code> and <code>pipeline_01.R</code> explanation,
@@ -230,11 +241,15 @@ <h2 id="define-the-input-dataset">2. Define the input dataset<a class="anchor" a
 <code class="sourceCode R"><span><span class="va">mk_adae</span> <span class="op">&lt;-</span> <span class="kw">function</span><span class="op">(</span><span class="va">study_metadata</span><span class="op">)</span> <span class="op">{</span></span>
 <span>  <span class="va">adae</span> <span class="op">&lt;-</span> <span class="fu">data.table</span><span class="fu">::</span><span class="fu"><a href="https://rdatatable.gitlab.io/data.table/reference/as.data.table.html" class="external-link">as.data.table</a></span><span class="op">(</span><span class="fu">pharmaverseadam</span><span class="fu">::</span><span class="va"><a href="https://pharmaverse.github.io/pharmaverseadam/main/reference/adae.html" class="external-link">adae</a></span><span class="op">)</span></span>
 <span>  <span class="va">adsl</span> <span class="op">&lt;-</span> <span class="fu">data.table</span><span class="fu">::</span><span class="fu"><a href="https://rdatatable.gitlab.io/data.table/reference/as.data.table.html" class="external-link">as.data.table</a></span><span class="op">(</span><span class="fu">pharmaverseadam</span><span class="fu">::</span><span class="va"><a href="https://pharmaverse.github.io/pharmaverseadam/main/reference/adsl.html" class="external-link">adsl</a></span><span class="op">)</span></span>
-<span>  <span class="va">adsl</span><span class="op">[</span>, <span class="va">AGEGR2</span> <span class="op">:=</span> <span class="fu">data.table</span><span class="fu">::</span><span class="fu"><a href="https://rdatatable.gitlab.io/data.table/reference/fcase.html" class="external-link">fcase</a></span><span class="op">(</span><span class="va">AGE</span> <span class="op">&lt;</span> <span class="fl">70</span>, <span class="st">"AGE &lt; 70"</span>,</span>
-<span>                                     <span class="va">AGE</span> <span class="op">&gt;=</span> <span class="fl">70</span>, <span class="st">"AGE &gt;= 70"</span><span class="op">)</span><span class="op">]</span></span>
+<span>  <span class="va">adsl</span><span class="op">[</span>, <span class="va">AGEGR2</span> <span class="op">:=</span> <span class="fu">data.table</span><span class="fu">::</span><span class="fu"><a href="https://rdatatable.gitlab.io/data.table/reference/fcase.html" class="external-link">fcase</a></span><span class="op">(</span></span>
+<span>    <span class="va">AGE</span> <span class="op">&lt;</span> <span class="fl">70</span>, <span class="st">"AGE &lt; 70"</span>,</span>
+<span>    <span class="va">AGE</span> <span class="op">&gt;=</span> <span class="fl">70</span>, <span class="st">"AGE &gt;= 70"</span></span>
+<span>  <span class="op">)</span><span class="op">]</span></span>
 <span>  <span class="va">adae_out</span> <span class="op">&lt;-</span></span>
-<span>    <span class="fu"><a href="https://rdrr.io/r/base/merge.html" class="external-link">merge</a></span><span class="op">(</span><span class="va">adsl</span>, <span class="va">adae</span><span class="op">[</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/sets.html" class="external-link">setdiff</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">adae</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">adsl</span><span class="op">)</span><span class="op">)</span>, <span class="st">"USUBJID"</span><span class="op">)</span>, with <span class="op">=</span></span>
-<span>                       <span class="cn">F</span><span class="op">]</span>, by <span class="op">=</span> <span class="st">"USUBJID"</span>, all <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span>
+<span>    <span class="fu"><a href="https://rdrr.io/r/base/merge.html" class="external-link">merge</a></span><span class="op">(</span><span class="va">adsl</span>, <span class="va">adae</span><span class="op">[</span>, <span class="fu"><a href="https://rdrr.io/r/base/c.html" class="external-link">c</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/sets.html" class="external-link">setdiff</a></span><span class="op">(</span><span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">adae</span><span class="op">)</span>, <span class="fu"><a href="https://rdrr.io/r/base/names.html" class="external-link">names</a></span><span class="op">(</span><span class="va">adsl</span><span class="op">)</span><span class="op">)</span>, <span class="st">"USUBJID"</span><span class="op">)</span>,</span>
+<span>      with <span class="op">=</span></span>
+<span>        <span class="cn">F</span></span>
+<span>    <span class="op">]</span>, by <span class="op">=</span> <span class="st">"USUBJID"</span>, all <span class="op">=</span> <span class="cn">TRUE</span><span class="op">)</span></span>
 <span>  <span class="va">adae_out</span><span class="op">[</span><span class="op">]</span></span>
 <span><span class="op">}</span></span></code></pre></div>
 </div>
@@ -267,7 +282,7 @@ <h2 id="run-the-analysis-pipeline">4. Run the analysis pipeline<a class="anchor"
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched target ep</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed target ep [0.03 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched target ep_id</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed target ep_id [0.009 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed target ep_id [0.01 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_fn_map_c85cfecb</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_fn_map_c85cfecb [0.032 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_fn_map</span></span></span>
@@ -276,59 +291,59 @@ <h2 id="run-the-analysis-pipeline">4. Run the analysis pipeline<a class="anchor"
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched target study_data</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed target study_data [0.035 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched target fn_map_tibble</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed target fn_map_tibble [0.004 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed target fn_map_tibble [0.005 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_and_data_c85cfecb</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_and_data_c85cfecb [0.01 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_and_data_c85cfecb [0.009 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_and_data</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch fn_map_ddcbeaef</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch fn_map_ddcbeaef [0.001 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch fn_map_9cf81814</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch fn_map_9cf81814 [0.001 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern fn_map</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch analysis_data_container_a4b422b1</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed branch analysis_data_container_a4b422b1 [0 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern analysis_data_container</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_with_data_key_a4b422b1</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_with_data_key_a4b422b1 [0.001 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_with_data_key_a4b422b1 [0 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_with_data_key</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_expanded_e741f3f8</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_expanded_e741f3f8 [0.02 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_expanded_e741f3f8 [0.019 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_expanded</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_event_index_5f7976c8</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_event_index_5f7976c8 [0.003 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_event_index</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_crit_endpoint_ebe3bbc0</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_crit_endpoint_ebe3bbc0 [0.004 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_crit_endpoint_3da7fd1e</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_crit_endpoint_3da7fd1e [0.004 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_crit_endpoint</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_crit_by_strata_by_trt_d8af90e8</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_crit_by_strata_by_trt_d8af90e8 [0.012 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_crit_by_strata_by_trt_1786b781</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_crit_by_strata_by_trt_1786b781 [0.008 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_crit_by_strata_by_trt</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_crit_by_strata_across_trt_843ad8b9</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_crit_by_strata_across_trt_843ad8b9 [0.003 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_crit_by_strata_across_trt_6a441418</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_crit_by_strata_across_trt_6a441418 [0.004 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_crit_by_strata_across_trt</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_prep_by_strata_across_trt_eb25bb25</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_prep_by_strata_across_trt_eb25bb25 [0.001 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_prep_by_strata_across_trt_89480a2b</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_prep_by_strata_across_trt_89480a2b [0.001 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_prep_by_strata_across_trt</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_prep_across_strata_across_trt_eb25bb25</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_prep_across_strata_across_trt_eb25bb25 [0.002 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_prep_across_strata_across_trt_89480a2b</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_prep_across_strata_across_trt_89480a2b [0.002 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_prep_across_strata_across_trt</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_prep_by_strata_by_trt_eb25bb25</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_prep_by_strata_by_trt_eb25bb25 [0.035 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_prep_by_strata_by_trt_89480a2b</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_prep_by_strata_by_trt_89480a2b [0.034 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_prep_by_strata_by_trt</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched target ep_rejected</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed target ep_rejected [0 seconds]</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_stat_by_strata_across_trt_0a80cb2c</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_stat_by_strata_across_trt_0a80cb2c [0 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_stat_by_strata_across_trt_a72d712a</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_stat_by_strata_across_trt_a72d712a [0.001 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_stat_by_strata_across_trt</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_stat_across_strata_across_trt_a619c1df</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_stat_across_strata_across_trt_a619c1df [0 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_stat_across_strata_across_trt_b2713725</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_stat_across_strata_across_trt_b2713725 [0 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_stat_across_strata_across_trt</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_stat_by_strata_by_trt_acada2e0</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_stat_by_strata_by_trt_acada2e0 [0.015 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ dispatched branch ep_stat_by_strata_by_trt_9535dd36</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed branch ep_stat_by_strata_by_trt_9535dd36 [0.01 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed pattern ep_stat_by_strata_by_trt</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched target ep_stat_nested</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ● completed target ep_stat_nested [0 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ● completed target ep_stat_nested [0.001 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ▶ dispatched target ep_stat</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## ● completed target ep_stat [0.004 seconds]</span></span></span>
-<span><span class="co"><span style="color: #BB0000;">## ▶ ended pipeline [0.441 seconds]</span></span></span>
+<span><span class="co"><span style="color: #BB0000;">## ▶ ended pipeline [0.44 seconds]</span></span></span>
 <span><span class="co"><span style="color: #BB0000;">## </span></span></span></code></pre>
 <p>Then, to see the results, you load the cached step of the pipeline
 corresponding to the results. In our case it will be
@@ -391,7 +406,7 @@ <h2 id="pass-the-data-on-to-tfl-formatting">5. Pass the data on to TFL formattin
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/results_datamodel.html b/articles/results_datamodel.html
index 29809e9..8de86e6 100644
--- a/articles/results_datamodel.html
+++ b/articles/results_datamodel.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Result Data Model">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Result Data Model">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
-</li>
-<li class="active nav-item dropdown">
+<li class="nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Result Data Model</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/results_datamodel.Rmd" class="external-link"><code>vignettes/results_datamodel.Rmd</code></a></small>
       <div class="d-none name"><code>results_datamodel.Rmd</code></div>
     </div>
 
@@ -607,7 +611,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/articles/results_datamodel2tfl.html b/articles/results_datamodel2tfl.html
index 77d5eb2..f5a2d0a 100644
--- a/articles/results_datamodel2tfl.html
+++ b/articles/results_datamodel2tfl.html
@@ -17,7 +17,8 @@
 <link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Mapping Results to TFLs">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
+<meta property="og:title" content="Mapping Results to TFLs">
 <meta property="og:description" content="ramnog">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
-<li class="nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
-</li>
-<li class="active nav-item dropdown">
+<li class="nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -101,7 +105,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <img src="../logo.png" class="logo" alt=""><h1>Mapping Results to TFLs</h1>
             
       
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/vignettes/results_datamodel2tfl.Rmd" class="external-link"><code>vignettes/results_datamodel2tfl.Rmd</code></a></small>
       <div class="d-none name"><code>results_datamodel2tfl.Rmd</code></div>
     </div>
 
@@ -115,7 +119,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/authors.html b/authors.html
index d7a7847..86c868d 100644
--- a/authors.html
+++ b/authors.html
@@ -1,16 +1,16 @@
 <!DOCTYPE html>
-<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><title>Authors and Citation • ramnog</title><!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="favicon-16x16.png"><link rel="icon" type="image/png" sizes="32x32" href="favicon-32x32.png"><link rel="apple-touch-icon" type="image/png" sizes="180x180" href="apple-touch-icon.png"><link rel="apple-touch-icon" type="image/png" sizes="120x120" href="apple-touch-icon-120x120.png"><link rel="apple-touch-icon" type="image/png" sizes="76x76" href="apple-touch-icon-76x76.png"><link rel="apple-touch-icon" type="image/png" sizes="60x60" href="apple-touch-icon-60x60.png"><script src="deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet"><script src="deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="pkgdown.js"></script><meta property="og:title" content="Authors and Citation"><meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
+<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><title>Authors and Citation • ramnog</title><!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="favicon-16x16.png"><link rel="icon" type="image/png" sizes="32x32" href="favicon-32x32.png"><link rel="apple-touch-icon" type="image/png" sizes="180x180" href="apple-touch-icon.png"><link rel="apple-touch-icon" type="image/png" sizes="120x120" href="apple-touch-icon-120x120.png"><link rel="apple-touch-icon" type="image/png" sizes="76x76" href="apple-touch-icon-76x76.png"><link rel="apple-touch-icon" type="image/png" sizes="60x60" href="apple-touch-icon-60x60.png"><script src="deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet"><script src="deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="pkgdown.js"></script><link href="extra.css" rel="stylesheet"><meta property="og:title" content="Authors and Citation"><meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
 <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script>
 <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script>
 <![endif]--></head><body>
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -19,48 +19,50 @@
 
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto"><li class="nav-item">
-  <a class="nav-link" href="articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="reference/index.html">Reference</a>
+  <a class="nav-link" href="articles/ramnog.html">Quick start</a>
 </li>
 <li class="nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul><form class="form-inline my-2 my-lg-0" role="search">
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="search.json" id="search-input" placeholder="Search for" autocomplete="off"></form>
 
-      <ul class="navbar-nav"></ul></div>
+      <ul class="navbar-nav"><li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul></div>
 
     
   </div>
@@ -74,36 +76,40 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
       <h2>Authors</h2>
       
       <ul class="list-unstyled"><li>
-          <p><strong>MEWP (Matthew David Phelps)</strong>. Author. 
+          <p><strong>Matthew David Phelps</strong>. Author. 
           </p>
         </li>
         <li>
-          <p><strong>NOSJ (Nicolai Skov Johnsen)</strong>. Author. 
+          <p><strong>Nicolai Skov Johnsen</strong>. Author. 
           </p>
         </li>
         <li>
-          <p><strong>HSPU (Henrik Sparre Spiegelhauer)</strong>. Author. 
+          <p><strong>Henrik Sparre Spiegelhauer</strong>. Author. 
           </p>
         </li>
         <li>
-          <p><strong>CINO (Christian Haargaard Olsen)</strong>. Author, maintainer. 
+          <p><strong>Christian Haargaard Olsen</strong>. Author, maintainer. 
           </p>
         </li>
       </ul></div>
 
     <div class="section level2 citation">
       <h2 id="citation">Citation</h2>
-      <p></p>
+      <p><small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/DESCRIPTION" class="external-link"><code>DESCRIPTION</code></a></small></p>
 
-      <p>MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen) (2024).
+      <p>Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen (2024).
 <em>ramnog: Facilitating AMNOG style analysis pipelines</em>.
-R package version 0.1.1, <a href="https://hta-pharma.github.io/ramnog/">https://hta-pharma.github.io/ramnog/</a>. 
+R package version 0.1.2, 
+https://github.com/hta-pharma/ramnog,
+https://app.codecov.io/gh/hta-pharma/ramnog, <a href="https://hta-pharma.github.io/ramnog/">https://hta-pharma.github.io/ramnog/</a>. 
 </p>
       <pre>@Manual{,
   title = {ramnog: Facilitating AMNOG style analysis pipelines},
-  author = {{MEWP (Matthew David Phelps)} and {NOSJ (Nicolai Skov Johnsen)} and {HSPU (Henrik Sparre Spiegelhauer)} and {CINO (Christian Haargaard Olsen)}},
+  author = {{Matthew David Phelps} and {Nicolai Skov Johnsen} and {Henrik Sparre Spiegelhauer} and {Christian Haargaard Olsen}},
   year = {2024},
-  note = {R package version 0.1.1},
+  note = {R package version 0.1.2, 
+https://github.com/hta-pharma/ramnog,
+https://app.codecov.io/gh/hta-pharma/ramnog},
   url = {https://hta-pharma.github.io/ramnog/},
 }</pre>
     </div>
@@ -112,7 +118,7 @@ <h2 id="citation">Citation</h2>
 
 
     <footer><div class="pkgdown-footer-left">
-  <p></p><p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+  <p></p><p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/deps/bootstrap-5.3.1/bootstrap.min.css b/deps/bootstrap-5.3.1/bootstrap.min.css
index b174f93..0425572 100644
--- a/deps/bootstrap-5.3.1/bootstrap.min.css
+++ b/deps/bootstrap-5.3.1/bootstrap.min.css
@@ -1,5 +1,5 @@
-@import url("font.css");:root{--bslib-bootstrap-version: 5;--bslib-preset-name: shiny;--bslib-preset-type: builtin}/*!
+@import url("font.css");:root{--bslib-bootstrap-version: 5;--bslib-preset-name: flatly;--bslib-preset-type: bootswatch}/*!
    * Bootstrap  v5.3.1 (https://getbootstrap.com/)
    * Copyright 2011-2023 The Bootstrap Authors
    * Licensed under MIT (https://github.com/twbs/bootstrap/blob/main/LICENSE)
-   */:root,[data-bs-theme="light"]{--bs-blue: #007bc2;--bs-indigo: #4b00c1;--bs-purple: #74149c;--bs-pink: #bf007f;--bs-red: #c10000;--bs-orange: #f45100;--bs-yellow: #f9b928;--bs-green: #00891a;--bs-teal: #00bf7f;--bs-cyan: #03c7e8;--bs-black: #000;--bs-white: #fff;--bs-gray: #707782;--bs-gray-dark: #343A46;--bs-gray-100: #f8f8f8;--bs-gray-200: #e9ecef;--bs-gray-300: #dee2e6;--bs-gray-400: #cdd4da;--bs-gray-500: #8D959E;--bs-gray-600: #707782;--bs-gray-700: #48505F;--bs-gray-800: #343A46;--bs-gray-900: #1D1F21;--bs-default: #dee2e6;--bs-primary: #007bc2;--bs-secondary: #404040;--bs-success: #00891a;--bs-info: #03c7e8;--bs-warning: #f9b928;--bs-danger: #c10000;--bs-light: #f8f8f8;--bs-dark: #202020;--bs-default-rgb: 222,226,230;--bs-primary-rgb: 0,123,194;--bs-secondary-rgb: 64,64,64;--bs-success-rgb: 0,137,26;--bs-info-rgb: 3,199,232;--bs-warning-rgb: 249,185,40;--bs-danger-rgb: 193,0,0;--bs-light-rgb: 248,248,248;--bs-dark-rgb: 32,32,32;--bs-primary-text-emphasis: 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auto}.btn-group>.btn-check:checked+.btn,.btn-group>.btn-check:focus+.btn,.btn-group>.btn:hover,.btn-group>.btn:focus,.btn-group>.btn:active,.btn-group>.btn.active,.btn-group-vertical>.btn-check:checked+.btn,.btn-group-vertical>.btn-check:focus+.btn,.btn-group-vertical>.btn:hover,.btn-group-vertical>.btn:focus,.btn-group-vertical>.btn:active,.btn-group-vertical>.btn.active{z-index:1}.btn-toolbar{display:flex;display:-webkit-flex;flex-wrap:wrap;-webkit-flex-wrap:wrap;justify-content:flex-start;-webkit-justify-content:flex-start}.btn-toolbar .input-group{width:auto}.btn-group{border-radius:var(--bs-border-radius)}.btn-group>:not(.btn-check:first-child)+.btn,.btn-group>.btn-group:not(:first-child){margin-left:calc(var(--bs-border-width) * -1)}.btn-group>.btn:not(:last-child):not(.dropdown-toggle),.btn-group>.btn.dropdown-toggle-split:first-child,.btn-group>.btn-group:not(:last-child)>.btn{border-top-right-radius:0;border-bottom-right-radius:0}.btn-group>.btn:nth-child(n + 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-1)}.btn-group-vertical>.btn:not(:last-child):not(.dropdown-toggle),.btn-group-vertical>.btn-group:not(:last-child)>.btn{border-bottom-right-radius:0;border-bottom-left-radius:0}.btn-group-vertical>.btn~.btn,.btn-group-vertical>.btn-group:not(:first-child)>.btn{border-top-left-radius:0;border-top-right-radius:0}.nav{--bs-nav-link-padding-x: 1rem;--bs-nav-link-padding-y: .5rem;--bs-nav-link-font-weight: ;--bs-nav-link-color: var(--bs-link-color);--bs-nav-link-hover-color: var(--bs-link-hover-color);--bs-nav-link-disabled-color: var(--bs-secondary-color);display:flex;display:-webkit-flex;flex-wrap:wrap;-webkit-flex-wrap:wrap;padding-left:0;margin-bottom:0;list-style:none}.nav-link{display:block;padding:var(--bs-nav-link-padding-y) var(--bs-nav-link-padding-x);font-size:var(--bs-nav-link-font-size);font-weight:var(--bs-nav-link-font-weight);color:var(--bs-nav-link-color);text-decoration:none;-webkit-text-decoration:none;-moz-text-decoration:none;-ms-text-decoration:none;-o-text-decoration:none;background:none;border:0;transition:color 0.15s ease-in-out,background-color 0.15s ease-in-out,border-color 0.15s ease-in-out}@media (prefers-reduced-motion: reduce){.nav-link{transition:none}}.nav-link:hover,.nav-link:focus{color:var(--bs-nav-link-hover-color)}.nav-link:focus-visible{outline:0;box-shadow:0 0 0 .25rem rgba(0,123,194,0.25)}.nav-link.disabled,.nav-link:disabled{color:var(--bs-nav-link-disabled-color);pointer-events:none;cursor:default}.nav-tabs{--bs-nav-tabs-border-width: var(--bs-border-width);--bs-nav-tabs-border-color: var(--bs-border-color);--bs-nav-tabs-border-radius: var(--bs-border-radius);--bs-nav-tabs-link-hover-border-color: var(--bs-secondary-bg) var(--bs-secondary-bg) var(--bs-border-color);--bs-nav-tabs-link-active-color: var(--bs-emphasis-color);--bs-nav-tabs-link-active-bg: var(--bs-body-bg);--bs-nav-tabs-link-active-border-color: var(--bs-border-color) var(--bs-border-color) var(--bs-body-bg);border-bottom:var(--bs-nav-tabs-border-width) solid var(--bs-nav-tabs-border-color)}.nav-tabs .nav-link{margin-bottom:calc(-1 * var(--bs-nav-tabs-border-width));border:var(--bs-nav-tabs-border-width) solid transparent;border-top-left-radius:var(--bs-nav-tabs-border-radius);border-top-right-radius:var(--bs-nav-tabs-border-radius)}.nav-tabs .nav-link:hover,.nav-tabs .nav-link:focus{isolation:isolate;border-color:var(--bs-nav-tabs-link-hover-border-color)}.nav-tabs .nav-link.active,.nav-tabs .nav-item.show .nav-link{color:var(--bs-nav-tabs-link-active-color);background-color:var(--bs-nav-tabs-link-active-bg);border-color:var(--bs-nav-tabs-link-active-border-color)}.nav-tabs .dropdown-menu{margin-top:calc(-1 * 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.show>.nav-link{font-weight:700;color:var(--bs-nav-underline-link-active-color);border-bottom-color:currentcolor}.nav-fill>.nav-link,.nav-fill .nav-item{flex:1 1 auto;-webkit-flex:1 1 auto;text-align:center}.nav-justified>.nav-link,.nav-justified .nav-item{flex-basis:0;-webkit-flex-basis:0;flex-grow:1;-webkit-flex-grow:1;text-align:center}.nav-fill .nav-item .nav-link,.nav-justified .nav-item .nav-link{width:100%}.tab-content>.tab-pane{display:none}.tab-content>.active{display:block}.navbar{--bs-navbar-padding-x: .66rem;--bs-navbar-padding-y: .5rem;--bs-navbar-color: rgba(var(--bs-emphasis-color-rgb), 0.65);--bs-navbar-hover-color: rgba(var(--bs-emphasis-color-rgb), 0.8);--bs-navbar-disabled-color: rgba(var(--bs-emphasis-color-rgb), 0.3);--bs-navbar-active-color: rgba(var(--bs-emphasis-color-rgb), 1);--bs-navbar-brand-padding-y: .3125rem;--bs-navbar-brand-margin-end: 1rem;--bs-navbar-brand-font-size: 1.25rem;--bs-navbar-brand-color: rgba(var(--bs-emphasis-color-rgb), 1);--bs-navbar-brand-hover-color: rgba(var(--bs-emphasis-color-rgb), 1);--bs-navbar-nav-link-padding-x: .5rem;--bs-navbar-toggler-padding-y: .25rem;--bs-navbar-toggler-padding-x: .75rem;--bs-navbar-toggler-font-size: 1.25rem;--bs-navbar-toggler-icon-bg: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 30 30'%3e%3cpath stroke='rgba%2829,31,33,0.75%29' stroke-linecap='round' stroke-miterlimit='10' stroke-width='2' d='M4 7h22M4 15h22M4 23h22'/%3e%3c/svg%3e");--bs-navbar-toggler-border-color: rgba(var(--bs-emphasis-color-rgb), 0.15);--bs-navbar-toggler-border-radius: var(--bs-border-radius);--bs-navbar-toggler-focus-width: .25rem;--bs-navbar-toggler-transition: box-shadow 0.15s ease-in-out;position:relative;display:flex;display:-webkit-flex;flex-wrap:wrap;-webkit-flex-wrap:wrap;align-items:center;-webkit-align-items:center;justify-content:space-between;-webkit-justify-content:space-between;padding:var(--bs-navbar-padding-y) 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.navbar-nav{flex-direction:row;-webkit-flex-direction:row}.navbar-expand-md .navbar-nav .dropdown-menu{position:absolute}.navbar-expand-md .navbar-nav .nav-link{padding-right:var(--bs-navbar-nav-link-padding-x);padding-left:var(--bs-navbar-nav-link-padding-x)}.navbar-expand-md .navbar-nav-scroll{overflow:visible}.navbar-expand-md .navbar-collapse{display:flex !important;display:-webkit-flex !important;flex-basis:auto;-webkit-flex-basis:auto}.navbar-expand-md .navbar-toggler{display:none}.navbar-expand-md .offcanvas{position:static;z-index:auto;flex-grow:1;-webkit-flex-grow:1;width:auto !important;height:auto !important;visibility:visible !important;background-color:transparent !important;border:0 !important;transform:none !important;transition:none}.navbar-expand-md .offcanvas .offcanvas-header{display:none}.navbar-expand-md .offcanvas .offcanvas-body{display:flex;display:-webkit-flex;flex-grow:0;-webkit-flex-grow:0;padding:0;overflow-y:visible}}@media (min-width: 992px){.navbar-expand-lg{flex-wrap:nowrap;-webkit-flex-wrap:nowrap;justify-content:flex-start;-webkit-justify-content:flex-start}.navbar-expand-lg .navbar-nav{flex-direction:row;-webkit-flex-direction:row}.navbar-expand-lg .navbar-nav .dropdown-menu{position:absolute}.navbar-expand-lg .navbar-nav .nav-link{padding-right:var(--bs-navbar-nav-link-padding-x);padding-left:var(--bs-navbar-nav-link-padding-x)}.navbar-expand-lg .navbar-nav-scroll{overflow:visible}.navbar-expand-lg .navbar-collapse{display:flex !important;display:-webkit-flex !important;flex-basis:auto;-webkit-flex-basis:auto}.navbar-expand-lg .navbar-toggler{display:none}.navbar-expand-lg .offcanvas{position:static;z-index:auto;flex-grow:1;-webkit-flex-grow:1;width:auto !important;height:auto !important;visibility:visible !important;background-color:transparent !important;border:0 !important;transform:none !important;transition:none}.navbar-expand-lg .offcanvas .offcanvas-header{display:none}.navbar-expand-lg .offcanvas 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.offcanvas{position:static;z-index:auto;flex-grow:1;-webkit-flex-grow:1;width:auto !important;height:auto !important;visibility:visible !important;background-color:transparent !important;border:0 !important;transform:none !important;transition:none}.navbar-expand-xxl .offcanvas .offcanvas-header{display:none}.navbar-expand-xxl .offcanvas .offcanvas-body{display:flex;display:-webkit-flex;flex-grow:0;-webkit-flex-grow:0;padding:0;overflow-y:visible}}.navbar-expand{flex-wrap:nowrap;-webkit-flex-wrap:nowrap;justify-content:flex-start;-webkit-justify-content:flex-start}.navbar-expand .navbar-nav{flex-direction:row;-webkit-flex-direction:row}.navbar-expand .navbar-nav .dropdown-menu{position:absolute}.navbar-expand .navbar-nav .nav-link{padding-right:var(--bs-navbar-nav-link-padding-x);padding-left:var(--bs-navbar-nav-link-padding-x)}.navbar-expand .navbar-nav-scroll{overflow:visible}.navbar-expand .navbar-collapse{display:flex !important;display:-webkit-flex 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ease-in-out,border-color 0.15s ease-in-out,box-shadow 0.15s ease-in-out,border-radius 0.15s ease;--bs-accordion-border-color: var(--bs-border-color);--bs-accordion-border-width: var(--bs-border-width);--bs-accordion-border-radius: var(--bs-border-radius);--bs-accordion-inner-border-radius: calc(var(--bs-border-radius) - (var(--bs-border-width)));--bs-accordion-btn-padding-x: 1.25rem;--bs-accordion-btn-padding-y: 1rem;--bs-accordion-btn-color: var(--bs-body-color);--bs-accordion-btn-bg: var(--bs-accordion-bg);--bs-accordion-btn-icon: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 16 16' fill='%231D1F21'%3e%3cpath fill-rule='evenodd' d='M1.646 4.646a.5.5 0 0 1 .708 0L8 10.293l5.646-5.647a.5.5 0 0 1 .708.708l-6 6a.5.5 0 0 1-.708 0l-6-6a.5.5 0 0 1 0-.708z'/%3e%3c/svg%3e");--bs-accordion-btn-icon-width: 1.25rem;--bs-accordion-btn-icon-transform: rotate(-180deg);--bs-accordion-btn-icon-transition: transform 0.2s ease-in-out;--bs-accordion-btn-active-icon: 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.accordion-button.collapsed{border-bottom-right-radius:var(--bs-accordion-inner-border-radius);border-bottom-left-radius:var(--bs-accordion-inner-border-radius)}.accordion-item:last-of-type .accordion-collapse{border-bottom-right-radius:var(--bs-accordion-border-radius);border-bottom-left-radius:var(--bs-accordion-border-radius)}.accordion-body{padding:var(--bs-accordion-body-padding-y) var(--bs-accordion-body-padding-x)}.accordion-flush .accordion-collapse{border-width:0}.accordion-flush .accordion-item{border-right:0;border-left:0;border-radius:0}.accordion-flush .accordion-item:first-child{border-top:0}.accordion-flush .accordion-item:last-child{border-bottom:0}.accordion-flush .accordion-item .accordion-button,.accordion-flush .accordion-item .accordion-button.collapsed{border-radius:0}[data-bs-theme="dark"] .accordion-button::after{--bs-accordion-btn-icon: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 16 16' fill='%2366b0da'%3e%3cpath 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var(--bs-breadcrumb-padding-x);margin-bottom:var(--bs-breadcrumb-margin-bottom);font-size:var(--bs-breadcrumb-font-size);list-style:none;background-color:var(--bs-breadcrumb-bg);border-radius:var(--bs-breadcrumb-border-radius)}.breadcrumb-item+.breadcrumb-item{padding-left:var(--bs-breadcrumb-item-padding-x)}.breadcrumb-item+.breadcrumb-item::before{float:left;padding-right:var(--bs-breadcrumb-item-padding-x);color:var(--bs-breadcrumb-divider-color);content:var(--bs-breadcrumb-divider, "/") /* rtl: var(--bs-breadcrumb-divider, "/") */}.breadcrumb-item.active{color:var(--bs-breadcrumb-item-active-color)}.pagination{--bs-pagination-padding-x: .75rem;--bs-pagination-padding-y: .375rem;--bs-pagination-font-size:1rem;--bs-pagination-color: var(--bs-link-color);--bs-pagination-bg: var(--bs-body-bg);--bs-pagination-border-width: var(--bs-border-width);--bs-pagination-border-color: var(--bs-border-color);--bs-pagination-border-radius: var(--bs-border-radius);--bs-pagination-hover-color: 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reduce){.page-link{transition:none}}.page-link:hover{z-index:2;color:var(--bs-pagination-hover-color);background-color:var(--bs-pagination-hover-bg);border-color:var(--bs-pagination-hover-border-color)}.page-link:focus{z-index:3;color:var(--bs-pagination-focus-color);background-color:var(--bs-pagination-focus-bg);outline:0;box-shadow:var(--bs-pagination-focus-box-shadow)}.page-link.active,.active>.page-link{z-index:3;color:var(--bs-pagination-active-color);background-color:var(--bs-pagination-active-bg);border-color:var(--bs-pagination-active-border-color)}.page-link.disabled,.disabled>.page-link{color:var(--bs-pagination-disabled-color);pointer-events:none;background-color:var(--bs-pagination-disabled-bg);border-color:var(--bs-pagination-disabled-border-color)}.page-item:not(:first-child) .page-link{margin-left:calc(var(--bs-border-width) * -1)}.page-item:first-child .page-link{border-top-left-radius:var(--bs-pagination-border-radius);border-bottom-left-radius:var(--bs-pagination-border-radius)}.page-item:last-child .page-link{border-top-right-radius:var(--bs-pagination-border-radius);border-bottom-right-radius:var(--bs-pagination-border-radius)}.pagination-lg{--bs-pagination-padding-x: 1.5rem;--bs-pagination-padding-y: .75rem;--bs-pagination-font-size:1.25rem;--bs-pagination-border-radius: var(--bs-border-radius-lg)}.pagination-sm{--bs-pagination-padding-x: .5rem;--bs-pagination-padding-y: .25rem;--bs-pagination-font-size:.875rem;--bs-pagination-border-radius: var(--bs-border-radius-sm)}.badge{--bs-badge-padding-x: .65em;--bs-badge-padding-y: .35em;--bs-badge-font-size:.75em;--bs-badge-font-weight: 700;--bs-badge-color: #fff;--bs-badge-border-radius: var(--bs-border-radius);display:inline-block;padding:var(--bs-badge-padding-y) var(--bs-badge-padding-x);font-size:var(--bs-badge-font-size);font-weight:var(--bs-badge-font-weight);line-height:1;color:var(--bs-badge-color);text-align:center;white-space:nowrap;vertical-align:baseline;border-radius:var(--bs-badge-border-radius)}.badge:empty{display:none}.btn .badge{position:relative;top:-1px}.alert{--bs-alert-bg: transparent;--bs-alert-padding-x: 1rem;--bs-alert-padding-y: 1rem;--bs-alert-margin-bottom: 1rem;--bs-alert-color: inherit;--bs-alert-border-color: transparent;--bs-alert-border: var(--bs-border-width) solid var(--bs-alert-border-color);--bs-alert-border-radius: var(--bs-border-radius);--bs-alert-link-color: inherit;position:relative;padding:var(--bs-alert-padding-y) var(--bs-alert-padding-x);margin-bottom:var(--bs-alert-margin-bottom);color:var(--bs-alert-color);background-color:var(--bs-alert-bg);border:var(--bs-alert-border);border-radius:var(--bs-alert-border-radius)}.alert-heading{color:inherit}.alert-link{font-weight:700;color:var(--bs-alert-link-color)}.alert-dismissible{padding-right:3rem}.alert-dismissible .btn-close{position:absolute;top:0;right:0;z-index:2;padding:1.25rem 1rem}.alert-default{--bs-alert-color: var(--bs-default-text-emphasis);--bs-alert-bg: var(--bs-default-bg-subtle);--bs-alert-border-color: var(--bs-default-border-subtle);--bs-alert-link-color: var(--bs-default-text-emphasis)}.alert-primary{--bs-alert-color: var(--bs-primary-text-emphasis);--bs-alert-bg: var(--bs-primary-bg-subtle);--bs-alert-border-color: var(--bs-primary-border-subtle);--bs-alert-link-color: var(--bs-primary-text-emphasis)}.alert-secondary{--bs-alert-color: var(--bs-secondary-text-emphasis);--bs-alert-bg: var(--bs-secondary-bg-subtle);--bs-alert-border-color: var(--bs-secondary-border-subtle);--bs-alert-link-color: var(--bs-secondary-text-emphasis)}.alert-success{--bs-alert-color: var(--bs-success-text-emphasis);--bs-alert-bg: var(--bs-success-bg-subtle);--bs-alert-border-color: var(--bs-success-border-subtle);--bs-alert-link-color: var(--bs-success-text-emphasis)}.alert-info{--bs-alert-color: var(--bs-info-text-emphasis);--bs-alert-bg: var(--bs-info-bg-subtle);--bs-alert-border-color: var(--bs-info-border-subtle);--bs-alert-link-color: var(--bs-info-text-emphasis)}.alert-warning{--bs-alert-color: var(--bs-warning-text-emphasis);--bs-alert-bg: var(--bs-warning-bg-subtle);--bs-alert-border-color: var(--bs-warning-border-subtle);--bs-alert-link-color: var(--bs-warning-text-emphasis)}.alert-danger{--bs-alert-color: var(--bs-danger-text-emphasis);--bs-alert-bg: var(--bs-danger-bg-subtle);--bs-alert-border-color: var(--bs-danger-border-subtle);--bs-alert-link-color: var(--bs-danger-text-emphasis)}.alert-light{--bs-alert-color: var(--bs-light-text-emphasis);--bs-alert-bg: var(--bs-light-bg-subtle);--bs-alert-border-color: var(--bs-light-border-subtle);--bs-alert-link-color: var(--bs-light-text-emphasis)}.alert-dark{--bs-alert-color: var(--bs-dark-text-emphasis);--bs-alert-bg: var(--bs-dark-bg-subtle);--bs-alert-border-color: var(--bs-dark-border-subtle);--bs-alert-link-color: var(--bs-dark-text-emphasis)}@keyframes progress-bar-stripes{0%{background-position-x:1rem}}.progress,.progress-stacked{--bs-progress-height: 1rem;--bs-progress-font-size:.75rem;--bs-progress-bg: var(--bs-secondary-bg);--bs-progress-border-radius: var(--bs-border-radius);--bs-progress-box-shadow: var(--bs-box-shadow-inset);--bs-progress-bar-color: #fff;--bs-progress-bar-bg: #007bc2;--bs-progress-bar-transition: width 0.6s ease;display:flex;display:-webkit-flex;height:var(--bs-progress-height);overflow:hidden;font-size:var(--bs-progress-font-size);background-color:var(--bs-progress-bg);border-radius:var(--bs-progress-border-radius)}.progress-bar{display:flex;display:-webkit-flex;flex-direction:column;-webkit-flex-direction:column;justify-content:center;-webkit-justify-content:center;overflow:hidden;color:var(--bs-progress-bar-color);text-align:center;white-space:nowrap;background-color:var(--bs-progress-bar-bg);transition:var(--bs-progress-bar-transition)}@media (prefers-reduced-motion: reduce){.progress-bar{transition:none}}.progress-bar-striped{background-image:linear-gradient(45deg, rgba(255,255,255,0.15) 25%, transparent 25%, transparent 50%, rgba(255,255,255,0.15) 50%, rgba(255,255,255,0.15) 75%, transparent 75%, transparent);background-size:var(--bs-progress-height) var(--bs-progress-height)}.progress-stacked>.progress{overflow:visible}.progress-stacked>.progress>.progress-bar{width:100%}.progress-bar-animated{animation:1s linear infinite progress-bar-stripes}@media (prefers-reduced-motion: reduce){.progress-bar-animated{animation:none}}.list-group{--bs-list-group-color: var(--bs-body-color);--bs-list-group-bg: var(--bs-body-bg);--bs-list-group-border-color: var(--bs-border-color);--bs-list-group-border-width: var(--bs-border-width);--bs-list-group-border-radius: var(--bs-border-radius);--bs-list-group-item-padding-x: 1rem;--bs-list-group-item-padding-y: .5rem;--bs-list-group-action-color: var(--bs-secondary-color);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-tertiary-bg);--bs-list-group-action-active-color: var(--bs-body-color);--bs-list-group-action-active-bg: var(--bs-secondary-bg);--bs-list-group-disabled-color: var(--bs-secondary-color);--bs-list-group-disabled-bg: 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";counter-increment:section}.list-group-item-action{width:100%;color:var(--bs-list-group-action-color);text-align:inherit}.list-group-item-action:hover,.list-group-item-action:focus{z-index:1;color:var(--bs-list-group-action-hover-color);text-decoration:none;background-color:var(--bs-list-group-action-hover-bg)}.list-group-item-action:active{color:var(--bs-list-group-action-active-color);background-color:var(--bs-list-group-action-active-bg)}.list-group-item{position:relative;display:block;padding:var(--bs-list-group-item-padding-y) var(--bs-list-group-item-padding-x);color:var(--bs-list-group-color);text-decoration:none;-webkit-text-decoration:none;-moz-text-decoration:none;-ms-text-decoration:none;-o-text-decoration:none;background-color:var(--bs-list-group-bg);border:var(--bs-list-group-border-width) solid 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var(--bs-list-group-border-width));border-top-width:var(--bs-list-group-border-width)}.list-group-horizontal{flex-direction:row;-webkit-flex-direction:row}.list-group-horizontal>.list-group-item:first-child:not(:last-child){border-bottom-left-radius:var(--bs-list-group-border-radius);border-top-right-radius:0}.list-group-horizontal>.list-group-item:last-child:not(:first-child){border-top-right-radius:var(--bs-list-group-border-radius);border-bottom-left-radius:0}.list-group-horizontal>.list-group-item.active{margin-top:0}.list-group-horizontal>.list-group-item+.list-group-item{border-top-width:var(--bs-list-group-border-width);border-left-width:0}.list-group-horizontal>.list-group-item+.list-group-item.active{margin-left:calc(-1 * var(--bs-list-group-border-width));border-left-width:var(--bs-list-group-border-width)}@media (min-width: 576px){.list-group-horizontal-sm{flex-direction:row;-webkit-flex-direction:row}.list-group-horizontal-sm>.list-group-item:first-child:not(:last-child){border-bottom-left-radius:var(--bs-list-group-border-radius);border-top-right-radius:0}.list-group-horizontal-sm>.list-group-item:last-child:not(:first-child){border-top-right-radius:var(--bs-list-group-border-radius);border-bottom-left-radius:0}.list-group-horizontal-sm>.list-group-item.active{margin-top:0}.list-group-horizontal-sm>.list-group-item+.list-group-item{border-top-width:var(--bs-list-group-border-width);border-left-width:0}.list-group-horizontal-sm>.list-group-item+.list-group-item.active{margin-left:calc(-1 * var(--bs-list-group-border-width));border-left-width:var(--bs-list-group-border-width)}}@media (min-width: 768px){.list-group-horizontal-md{flex-direction:row;-webkit-flex-direction:row}.list-group-horizontal-md>.list-group-item:first-child:not(:last-child){border-bottom-left-radius:var(--bs-list-group-border-radius);border-top-right-radius:0}.list-group-horizontal-md>.list-group-item:last-child:not(:first-child){border-top-right-radius:var(--bs-list-group-border-radius);border-bottom-left-radius:0}.list-group-horizontal-md>.list-group-item.active{margin-top:0}.list-group-horizontal-md>.list-group-item+.list-group-item{border-top-width:var(--bs-list-group-border-width);border-left-width:0}.list-group-horizontal-md>.list-group-item+.list-group-item.active{margin-left:calc(-1 * var(--bs-list-group-border-width));border-left-width:var(--bs-list-group-border-width)}}@media (min-width: 992px){.list-group-horizontal-lg{flex-direction:row;-webkit-flex-direction:row}.list-group-horizontal-lg>.list-group-item:first-child:not(:last-child){border-bottom-left-radius:var(--bs-list-group-border-radius);border-top-right-radius:0}.list-group-horizontal-lg>.list-group-item:last-child:not(:first-child){border-top-right-radius:var(--bs-list-group-border-radius);border-bottom-left-radius:0}.list-group-horizontal-lg>.list-group-item.active{margin-top:0}.list-group-horizontal-lg>.list-group-item+.list-group-item{border-top-width:var(--bs-list-group-border-width);border-left-width:0}.list-group-horizontal-lg>.list-group-item+.list-group-item.active{margin-left:calc(-1 * var(--bs-list-group-border-width));border-left-width:var(--bs-list-group-border-width)}}@media (min-width: 1200px){.list-group-horizontal-xl{flex-direction:row;-webkit-flex-direction:row}.list-group-horizontal-xl>.list-group-item:first-child:not(:last-child){border-bottom-left-radius:var(--bs-list-group-border-radius);border-top-right-radius:0}.list-group-horizontal-xl>.list-group-item:last-child:not(:first-child){border-top-right-radius:var(--bs-list-group-border-radius);border-bottom-left-radius:0}.list-group-horizontal-xl>.list-group-item.active{margin-top:0}.list-group-horizontal-xl>.list-group-item+.list-group-item{border-top-width:var(--bs-list-group-border-width);border-left-width:0}.list-group-horizontal-xl>.list-group-item+.list-group-item.active{margin-left:calc(-1 * var(--bs-list-group-border-width));border-left-width:var(--bs-list-group-border-width)}}@media (min-width: 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var(--bs-secondary-text-emphasis);--bs-list-group-active-border-color: var(--bs-secondary-text-emphasis)}.list-group-item-success{--bs-list-group-color: var(--bs-success-text-emphasis);--bs-list-group-bg: var(--bs-success-bg-subtle);--bs-list-group-border-color: var(--bs-success-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-success-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-success-border-subtle);--bs-list-group-active-color: var(--bs-success-bg-subtle);--bs-list-group-active-bg: var(--bs-success-text-emphasis);--bs-list-group-active-border-color: var(--bs-success-text-emphasis)}.list-group-item-info{--bs-list-group-color: var(--bs-info-text-emphasis);--bs-list-group-bg: var(--bs-info-bg-subtle);--bs-list-group-border-color: var(--bs-info-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-info-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-info-border-subtle);--bs-list-group-active-color: var(--bs-info-bg-subtle);--bs-list-group-active-bg: var(--bs-info-text-emphasis);--bs-list-group-active-border-color: var(--bs-info-text-emphasis)}.list-group-item-warning{--bs-list-group-color: var(--bs-warning-text-emphasis);--bs-list-group-bg: var(--bs-warning-bg-subtle);--bs-list-group-border-color: var(--bs-warning-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-warning-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-warning-border-subtle);--bs-list-group-active-color: var(--bs-warning-bg-subtle);--bs-list-group-active-bg: var(--bs-warning-text-emphasis);--bs-list-group-active-border-color: var(--bs-warning-text-emphasis)}.list-group-item-danger{--bs-list-group-color: var(--bs-danger-text-emphasis);--bs-list-group-bg: var(--bs-danger-bg-subtle);--bs-list-group-border-color: var(--bs-danger-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-danger-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-danger-border-subtle);--bs-list-group-active-color: var(--bs-danger-bg-subtle);--bs-list-group-active-bg: var(--bs-danger-text-emphasis);--bs-list-group-active-border-color: var(--bs-danger-text-emphasis)}.list-group-item-light{--bs-list-group-color: var(--bs-light-text-emphasis);--bs-list-group-bg: var(--bs-light-bg-subtle);--bs-list-group-border-color: var(--bs-light-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-light-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-light-border-subtle);--bs-list-group-active-color: var(--bs-light-bg-subtle);--bs-list-group-active-bg: var(--bs-light-text-emphasis);--bs-list-group-active-border-color: var(--bs-light-text-emphasis)}.list-group-item-dark{--bs-list-group-color: var(--bs-dark-text-emphasis);--bs-list-group-bg: var(--bs-dark-bg-subtle);--bs-list-group-border-color: var(--bs-dark-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-dark-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-dark-border-subtle);--bs-list-group-active-color: var(--bs-dark-bg-subtle);--bs-list-group-active-bg: var(--bs-dark-text-emphasis);--bs-list-group-active-border-color: var(--bs-dark-text-emphasis)}.btn-close{--bs-btn-close-color: #000;--bs-btn-close-bg: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' 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.375rem)}.was-validated .form-select:invalid:focus,.form-select.is-invalid:focus{border-color:var(--bs-form-invalid-border-color);box-shadow:0 0 0 .25rem rgba(var(--bs-danger-rgb), 0.25)}.was-validated .form-control-color:invalid,.form-control-color.is-invalid{width:calc(3rem + calc(1.5em + .75rem))}.was-validated .form-check-input:invalid,.form-check-input.is-invalid{border-color:var(--bs-form-invalid-border-color)}.was-validated .form-check-input:invalid:checked,.form-check-input.is-invalid:checked{background-color:var(--bs-form-invalid-color)}.was-validated .form-check-input:invalid:focus,.form-check-input.is-invalid:focus{box-shadow:0 0 0 .25rem rgba(var(--bs-danger-rgb), 0.25)}.was-validated .form-check-input:invalid~.form-check-label,.form-check-input.is-invalid~.form-check-label{color:var(--bs-form-invalid-color)}.form-check-inline .form-check-input~.invalid-feedback{margin-left:.5em}.was-validated .input-group>.form-control:not(:focus):invalid,.input-group>.form-control:not(:focus).is-invalid,.was-validated .input-group>.form-select:not(:focus):invalid,.input-group>.form-select:not(:focus).is-invalid,.was-validated .input-group>.form-floating:not(:focus-within):invalid,.input-group>.form-floating:not(:focus-within).is-invalid{z-index:4}.btn{--bs-btn-padding-x: .75rem;--bs-btn-padding-y: .375rem;--bs-btn-font-family: ;--bs-btn-font-size:1rem;--bs-btn-font-weight: 400;--bs-btn-line-height: 1.5;--bs-btn-color: var(--bs-body-color);--bs-btn-bg: transparent;--bs-btn-border-width: var(--bs-border-width);--bs-btn-border-color: transparent;--bs-btn-border-radius: var(--bs-border-radius);--bs-btn-hover-border-color: transparent;--bs-btn-box-shadow: inset 0 1px 0 rgba(255,255,255,0.15),0 1px 1px rgba(0,0,0,0.075);--bs-btn-disabled-opacity: .65;--bs-btn-focus-box-shadow: 0 0 0 .25rem rgba(var(--bs-btn-focus-shadow-rgb), .5);display:inline-block;padding:var(--bs-btn-padding-y) 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reduce){.btn{transition:none}}.btn:hover{color:var(--bs-btn-hover-color);background-color:var(--bs-btn-hover-bg);border-color:var(--bs-btn-hover-border-color)}.btn-check+.btn:hover{color:var(--bs-btn-color);background-color:var(--bs-btn-bg);border-color:var(--bs-btn-border-color)}.btn:focus-visible{color:var(--bs-btn-hover-color);background-color:var(--bs-btn-hover-bg);border-color:var(--bs-btn-hover-border-color);outline:0;box-shadow:var(--bs-btn-focus-box-shadow)}.btn-check:focus-visible+.btn{border-color:var(--bs-btn-hover-border-color);outline:0;box-shadow:var(--bs-btn-focus-box-shadow)}.btn-check:checked+.btn,:not(.btn-check)+.btn:active,.btn:first-child:active,.btn.active,.btn.show{color:var(--bs-btn-active-color);background-color:var(--bs-btn-active-bg);border-color:var(--bs-btn-active-border-color)}.btn-check:checked+.btn:focus-visible,:not(.btn-check)+.btn:active:focus-visible,.btn:first-child:active:focus-visible,.btn.active:focus-visible,.btn.show:focus-visible{box-shadow:var(--bs-btn-focus-box-shadow)}.btn:disabled,.btn.disabled,fieldset:disabled .btn{color:var(--bs-btn-disabled-color);pointer-events:none;background-color:var(--bs-btn-disabled-bg);border-color:var(--bs-btn-disabled-border-color);opacity:var(--bs-btn-disabled-opacity)}.btn-default{--bs-btn-color: #fff;--bs-btn-bg: #95a5a6;--bs-btn-border-color: #95a5a6;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #7f8c8d;--bs-btn-hover-border-color: #778485;--bs-btn-focus-shadow-rgb: 165,179,179;--bs-btn-active-color: #fff;--bs-btn-active-bg: #778485;--bs-btn-active-border-color: #707c7d;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #fff;--bs-btn-disabled-bg: #95a5a6;--bs-btn-disabled-border-color: #95a5a6}.btn-primary{--bs-btn-color: #fff;--bs-btn-bg: #2c3e50;--bs-btn-border-color: #2c3e50;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #253544;--bs-btn-hover-border-color: #233240;--bs-btn-focus-shadow-rgb: 76,91,106;--bs-btn-active-color: #fff;--bs-btn-active-bg: #233240;--bs-btn-active-border-color: #212f3c;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #fff;--bs-btn-disabled-bg: #2c3e50;--bs-btn-disabled-border-color: #2c3e50}.btn-secondary,.btn-default:not(.btn-primary):not(.btn-info):not(.btn-success):not(.btn-warning):not(.btn-danger):not(.btn-dark):not(.btn-light):not([class*='btn-outline-']){--bs-btn-color: #fff;--bs-btn-bg: #95a5a6;--bs-btn-border-color: #95a5a6;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #7f8c8d;--bs-btn-hover-border-color: #778485;--bs-btn-focus-shadow-rgb: 165,179,179;--bs-btn-active-color: #fff;--bs-btn-active-bg: #778485;--bs-btn-active-border-color: #707c7d;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #fff;--bs-btn-disabled-bg: #95a5a6;--bs-btn-disabled-border-color: #95a5a6}.btn-success{--bs-btn-color: #fff;--bs-btn-bg: #18bc9c;--bs-btn-border-color: #18bc9c;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #14a085;--bs-btn-hover-border-color: #13967d;--bs-btn-focus-shadow-rgb: 59,198,171;--bs-btn-active-color: #fff;--bs-btn-active-bg: #13967d;--bs-btn-active-border-color: #128d75;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #fff;--bs-btn-disabled-bg: #18bc9c;--bs-btn-disabled-border-color: #18bc9c}.btn-info{--bs-btn-color: #fff;--bs-btn-bg: #3498db;--bs-btn-border-color: #3498db;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #2c81ba;--bs-btn-hover-border-color: #2a7aaf;--bs-btn-focus-shadow-rgb: 82,167,224;--bs-btn-active-color: #fff;--bs-btn-active-bg: #2a7aaf;--bs-btn-active-border-color: #2772a4;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #fff;--bs-btn-disabled-bg: #3498db;--bs-btn-disabled-border-color: #3498db}.btn-warning{--bs-btn-color: #fff;--bs-btn-bg: #f39c12;--bs-btn-border-color: #f39c12;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #cf850f;--bs-btn-hover-border-color: #c27d0e;--bs-btn-focus-shadow-rgb: 245,171,54;--bs-btn-active-color: #fff;--bs-btn-active-bg: #c27d0e;--bs-btn-active-border-color: #b6750e;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #fff;--bs-btn-disabled-bg: #f39c12;--bs-btn-disabled-border-color: #f39c12}.btn-danger{--bs-btn-color: #fff;--bs-btn-bg: #e74c3c;--bs-btn-border-color: #e74c3c;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #c44133;--bs-btn-hover-border-color: #b93d30;--bs-btn-focus-shadow-rgb: 235,103,89;--bs-btn-active-color: #fff;--bs-btn-active-bg: #b93d30;--bs-btn-active-border-color: #ad392d;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #fff;--bs-btn-disabled-bg: #e74c3c;--bs-btn-disabled-border-color: #e74c3c}.btn-light{--bs-btn-color: #000;--bs-btn-bg: #ecf0f1;--bs-btn-border-color: #ecf0f1;--bs-btn-hover-color: #000;--bs-btn-hover-bg: #c9cccd;--bs-btn-hover-border-color: #bdc0c1;--bs-btn-focus-shadow-rgb: 201,204,205;--bs-btn-active-color: #000;--bs-btn-active-bg: #bdc0c1;--bs-btn-active-border-color: #b1b4b5;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #000;--bs-btn-disabled-bg: #ecf0f1;--bs-btn-disabled-border-color: #ecf0f1}.btn-dark{--bs-btn-color: #fff;--bs-btn-bg: #7b8a8b;--bs-btn-border-color: #7b8a8b;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #8f9c9c;--bs-btn-hover-border-color: #889697;--bs-btn-focus-shadow-rgb: 143,156,156;--bs-btn-active-color: #fff;--bs-btn-active-bg: #95a1a2;--bs-btn-active-border-color: #889697;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #fff;--bs-btn-disabled-bg: #7b8a8b;--bs-btn-disabled-border-color: #7b8a8b}.btn-outline-default{--bs-btn-color: #95a5a6;--bs-btn-border-color: #95a5a6;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #95a5a6;--bs-btn-hover-border-color: #95a5a6;--bs-btn-focus-shadow-rgb: 149,165,166;--bs-btn-active-color: #fff;--bs-btn-active-bg: #95a5a6;--bs-btn-active-border-color: #95a5a6;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #95a5a6;--bs-btn-disabled-bg: transparent;--bs-btn-disabled-border-color: #95a5a6;--bs-btn-bg: transparent;--bs-gradient: none}.btn-outline-primary{--bs-btn-color: #2c3e50;--bs-btn-border-color: #2c3e50;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #2c3e50;--bs-btn-hover-border-color: #2c3e50;--bs-btn-focus-shadow-rgb: 44,62,80;--bs-btn-active-color: #fff;--bs-btn-active-bg: #2c3e50;--bs-btn-active-border-color: #2c3e50;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #2c3e50;--bs-btn-disabled-bg: transparent;--bs-btn-disabled-border-color: #2c3e50;--bs-btn-bg: transparent;--bs-gradient: none}.btn-outline-secondary{--bs-btn-color: #95a5a6;--bs-btn-border-color: #95a5a6;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #95a5a6;--bs-btn-hover-border-color: #95a5a6;--bs-btn-focus-shadow-rgb: 149,165,166;--bs-btn-active-color: #fff;--bs-btn-active-bg: #95a5a6;--bs-btn-active-border-color: #95a5a6;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #95a5a6;--bs-btn-disabled-bg: transparent;--bs-btn-disabled-border-color: #95a5a6;--bs-btn-bg: transparent;--bs-gradient: none}.btn-outline-success{--bs-btn-color: #18bc9c;--bs-btn-border-color: #18bc9c;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #18bc9c;--bs-btn-hover-border-color: #18bc9c;--bs-btn-focus-shadow-rgb: 24,188,156;--bs-btn-active-color: #fff;--bs-btn-active-bg: #18bc9c;--bs-btn-active-border-color: #18bc9c;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #18bc9c;--bs-btn-disabled-bg: transparent;--bs-btn-disabled-border-color: #18bc9c;--bs-btn-bg: transparent;--bs-gradient: none}.btn-outline-info{--bs-btn-color: #3498db;--bs-btn-border-color: #3498db;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #3498db;--bs-btn-hover-border-color: #3498db;--bs-btn-focus-shadow-rgb: 52,152,219;--bs-btn-active-color: #fff;--bs-btn-active-bg: #3498db;--bs-btn-active-border-color: #3498db;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #3498db;--bs-btn-disabled-bg: transparent;--bs-btn-disabled-border-color: #3498db;--bs-btn-bg: transparent;--bs-gradient: none}.btn-outline-warning{--bs-btn-color: #f39c12;--bs-btn-border-color: #f39c12;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #f39c12;--bs-btn-hover-border-color: #f39c12;--bs-btn-focus-shadow-rgb: 243,156,18;--bs-btn-active-color: #fff;--bs-btn-active-bg: #f39c12;--bs-btn-active-border-color: #f39c12;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #f39c12;--bs-btn-disabled-bg: transparent;--bs-btn-disabled-border-color: #f39c12;--bs-btn-bg: transparent;--bs-gradient: none}.btn-outline-danger{--bs-btn-color: #e74c3c;--bs-btn-border-color: #e74c3c;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #e74c3c;--bs-btn-hover-border-color: #e74c3c;--bs-btn-focus-shadow-rgb: 231,76,60;--bs-btn-active-color: #fff;--bs-btn-active-bg: #e74c3c;--bs-btn-active-border-color: #e74c3c;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #e74c3c;--bs-btn-disabled-bg: transparent;--bs-btn-disabled-border-color: #e74c3c;--bs-btn-bg: transparent;--bs-gradient: none}.btn-outline-light{--bs-btn-color: #ecf0f1;--bs-btn-border-color: #ecf0f1;--bs-btn-hover-color: #000;--bs-btn-hover-bg: #ecf0f1;--bs-btn-hover-border-color: #ecf0f1;--bs-btn-focus-shadow-rgb: 236,240,241;--bs-btn-active-color: #000;--bs-btn-active-bg: #ecf0f1;--bs-btn-active-border-color: #ecf0f1;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #ecf0f1;--bs-btn-disabled-bg: transparent;--bs-btn-disabled-border-color: #ecf0f1;--bs-btn-bg: transparent;--bs-gradient: none}.btn-outline-dark{--bs-btn-color: #7b8a8b;--bs-btn-border-color: #7b8a8b;--bs-btn-hover-color: #fff;--bs-btn-hover-bg: #7b8a8b;--bs-btn-hover-border-color: #7b8a8b;--bs-btn-focus-shadow-rgb: 123,138,139;--bs-btn-active-color: #fff;--bs-btn-active-bg: #7b8a8b;--bs-btn-active-border-color: #7b8a8b;--bs-btn-active-shadow: inset 0 3px 5px rgba(0,0,0,0.125);--bs-btn-disabled-color: #7b8a8b;--bs-btn-disabled-bg: transparent;--bs-btn-disabled-border-color: #7b8a8b;--bs-btn-bg: transparent;--bs-gradient: none}.btn-link{--bs-btn-font-weight: 400;--bs-btn-color: var(--bs-link-color);--bs-btn-bg: transparent;--bs-btn-border-color: transparent;--bs-btn-hover-color: var(--bs-link-hover-color);--bs-btn-hover-border-color: transparent;--bs-btn-active-color: var(--bs-link-hover-color);--bs-btn-active-border-color: transparent;--bs-btn-disabled-color: #95a5a6;--bs-btn-disabled-border-color: transparent;--bs-btn-box-shadow: 0 0 0 #000;--bs-btn-focus-shadow-rgb: 59,198,171;text-decoration:underline;-webkit-text-decoration:underline;-moz-text-decoration:underline;-ms-text-decoration:underline;-o-text-decoration:underline}.btn-link:focus-visible{color:var(--bs-btn-color)}.btn-link:hover{color:var(--bs-btn-hover-color)}.btn-lg,.btn-group-lg>.btn{--bs-btn-padding-y: .5rem;--bs-btn-padding-x: 1rem;--bs-btn-font-size:1.25rem;--bs-btn-border-radius: var(--bs-border-radius-lg)}.btn-sm,.btn-group-sm>.btn{--bs-btn-padding-y: .25rem;--bs-btn-padding-x: .5rem;--bs-btn-font-size:.875rem;--bs-btn-border-radius: var(--bs-border-radius-sm)}.fade{transition:opacity 0.15s linear}@media (prefers-reduced-motion: reduce){.fade{transition:none}}.fade:not(.show){opacity:0}.collapse:not(.show){display:none}.collapsing{height:0;overflow:hidden;transition:height 0.35s ease}@media (prefers-reduced-motion: reduce){.collapsing{transition:none}}.collapsing.collapse-horizontal{width:0;height:auto;transition:width 0.35s ease}@media (prefers-reduced-motion: reduce){.collapsing.collapse-horizontal{transition:none}}.dropup,.dropend,.dropdown,.dropstart,.dropup-center,.dropdown-center{position:relative}.dropdown-toggle{white-space:nowrap}.dropdown-toggle::after{display:inline-block;margin-left:.255em;vertical-align:.255em;content:"";border-top:.3em solid;border-right:.3em solid transparent;border-bottom:0;border-left:.3em solid transparent}.dropdown-toggle:empty::after{margin-left:0}.dropdown-menu{--bs-dropdown-zindex: 1000;--bs-dropdown-min-width: 10rem;--bs-dropdown-padding-x: 0;--bs-dropdown-padding-y: .5rem;--bs-dropdown-spacer: .125rem;--bs-dropdown-font-size:1rem;--bs-dropdown-color: var(--bs-body-color);--bs-dropdown-bg: var(--bs-body-bg);--bs-dropdown-border-color: var(--bs-border-color-translucent);--bs-dropdown-border-radius: var(--bs-border-radius);--bs-dropdown-border-width: var(--bs-border-width);--bs-dropdown-inner-border-radius: calc(var(--bs-border-radius) - var(--bs-border-width));--bs-dropdown-divider-bg: var(--bs-border-color-translucent);--bs-dropdown-divider-margin-y: .5rem;--bs-dropdown-box-shadow: 0 0.5rem 1rem rgba(0,0,0,0.15);--bs-dropdown-link-color: #7b8a8b;--bs-dropdown-link-hover-color: #fff;--bs-dropdown-link-hover-bg: #2c3e50;--bs-dropdown-link-active-color: #fff;--bs-dropdown-link-active-bg: #2c3e50;--bs-dropdown-link-disabled-color: var(--bs-tertiary-color);--bs-dropdown-item-padding-x: 1rem;--bs-dropdown-item-padding-y: .25rem;--bs-dropdown-header-color: #95a5a6;--bs-dropdown-header-padding-x: 1rem;--bs-dropdown-header-padding-y: .5rem;position:absolute;z-index:var(--bs-dropdown-zindex);display:none;min-width:var(--bs-dropdown-min-width);padding:var(--bs-dropdown-padding-y) var(--bs-dropdown-padding-x);margin:0;font-size:var(--bs-dropdown-font-size);color:var(--bs-dropdown-color);text-align:left;list-style:none;background-color:var(--bs-dropdown-bg);background-clip:padding-box;border:var(--bs-dropdown-border-width) solid var(--bs-dropdown-border-color);border-radius:var(--bs-dropdown-border-radius)}.dropdown-menu[data-bs-popper]{top:100%;left:0;margin-top:var(--bs-dropdown-spacer)}.dropdown-menu-start{--bs-position: start}.dropdown-menu-start[data-bs-popper]{right:auto;left:0}.dropdown-menu-end{--bs-position: end}.dropdown-menu-end[data-bs-popper]{right:0;left:auto}@media (min-width: 576px){.dropdown-menu-sm-start{--bs-position: start}.dropdown-menu-sm-start[data-bs-popper]{right:auto;left:0}.dropdown-menu-sm-end{--bs-position: end}.dropdown-menu-sm-end[data-bs-popper]{right:0;left:auto}}@media (min-width: 768px){.dropdown-menu-md-start{--bs-position: start}.dropdown-menu-md-start[data-bs-popper]{right:auto;left:0}.dropdown-menu-md-end{--bs-position: end}.dropdown-menu-md-end[data-bs-popper]{right:0;left:auto}}@media (min-width: 992px){.dropdown-menu-lg-start{--bs-position: start}.dropdown-menu-lg-start[data-bs-popper]{right:auto;left:0}.dropdown-menu-lg-end{--bs-position: end}.dropdown-menu-lg-end[data-bs-popper]{right:0;left:auto}}@media (min-width: 1200px){.dropdown-menu-xl-start{--bs-position: start}.dropdown-menu-xl-start[data-bs-popper]{right:auto;left:0}.dropdown-menu-xl-end{--bs-position: end}.dropdown-menu-xl-end[data-bs-popper]{right:0;left:auto}}@media (min-width: 1400px){.dropdown-menu-xxl-start{--bs-position: start}.dropdown-menu-xxl-start[data-bs-popper]{right:auto;left:0}.dropdown-menu-xxl-end{--bs-position: end}.dropdown-menu-xxl-end[data-bs-popper]{right:0;left:auto}}.dropup .dropdown-menu[data-bs-popper]{top:auto;bottom:100%;margin-top:0;margin-bottom:var(--bs-dropdown-spacer)}.dropup .dropdown-toggle::after{display:inline-block;margin-left:.255em;vertical-align:.255em;content:"";border-top:0;border-right:.3em solid transparent;border-bottom:.3em solid;border-left:.3em solid transparent}.dropup .dropdown-toggle:empty::after{margin-left:0}.dropend .dropdown-menu[data-bs-popper]{top:0;right:auto;left:100%;margin-top:0;margin-left:var(--bs-dropdown-spacer)}.dropend .dropdown-toggle::after{display:inline-block;margin-left:.255em;vertical-align:.255em;content:"";border-top:.3em solid transparent;border-right:0;border-bottom:.3em solid transparent;border-left:.3em solid}.dropend .dropdown-toggle:empty::after{margin-left:0}.dropend 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auto}.btn-group>.btn-check:checked+.btn,.btn-group>.btn-check:focus+.btn,.btn-group>.btn:hover,.btn-group>.btn:focus,.btn-group>.btn:active,.btn-group>.btn.active,.btn-group-vertical>.btn-check:checked+.btn,.btn-group-vertical>.btn-check:focus+.btn,.btn-group-vertical>.btn:hover,.btn-group-vertical>.btn:focus,.btn-group-vertical>.btn:active,.btn-group-vertical>.btn.active{z-index:1}.btn-toolbar{display:flex;display:-webkit-flex;flex-wrap:wrap;-webkit-flex-wrap:wrap;justify-content:flex-start;-webkit-justify-content:flex-start}.btn-toolbar .input-group{width:auto}.btn-group{border-radius:var(--bs-border-radius)}.btn-group>:not(.btn-check:first-child)+.btn,.btn-group>.btn-group:not(:first-child){margin-left:calc(var(--bs-border-width) * -1)}.btn-group>.btn:not(:last-child):not(.dropdown-toggle),.btn-group>.btn.dropdown-toggle-split:first-child,.btn-group>.btn-group:not(:last-child)>.btn{border-top-right-radius:0;border-bottom-right-radius:0}.btn-group>.btn:nth-child(n + 3),.btn-group>:not(.btn-check)+.btn,.btn-group>.btn-group:not(:first-child)>.btn{border-top-left-radius:0;border-bottom-left-radius:0}.dropdown-toggle-split{padding-right:.5625rem;padding-left:.5625rem}.dropdown-toggle-split::after,.dropup .dropdown-toggle-split::after,.dropend .dropdown-toggle-split::after{margin-left:0}.dropstart .dropdown-toggle-split::before{margin-right:0}.btn-sm+.dropdown-toggle-split,.btn-group-sm>.btn+.dropdown-toggle-split{padding-right:.375rem;padding-left:.375rem}.btn-lg+.dropdown-toggle-split,.btn-group-lg>.btn+.dropdown-toggle-split{padding-right:.75rem;padding-left:.75rem}.btn-group-vertical{flex-direction:column;-webkit-flex-direction:column;align-items:flex-start;-webkit-align-items:flex-start;justify-content:center;-webkit-justify-content:center}.btn-group-vertical>.btn,.btn-group-vertical>.btn-group{width:100%}.btn-group-vertical>.btn:not(:first-child),.btn-group-vertical>.btn-group:not(:first-child){margin-top:calc(var(--bs-border-width) * 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.offcanvas{position:static;z-index:auto;flex-grow:1;-webkit-flex-grow:1;width:auto !important;height:auto !important;visibility:visible !important;background-color:transparent !important;border:0 !important;transform:none !important;transition:none}.navbar-expand-xxl .offcanvas .offcanvas-header{display:none}.navbar-expand-xxl .offcanvas .offcanvas-body{display:flex;display:-webkit-flex;flex-grow:0;-webkit-flex-grow:0;padding:0;overflow-y:visible}}.navbar-expand{flex-wrap:nowrap;-webkit-flex-wrap:nowrap;justify-content:flex-start;-webkit-justify-content:flex-start}.navbar-expand .navbar-nav{flex-direction:row;-webkit-flex-direction:row}.navbar-expand .navbar-nav .dropdown-menu{position:absolute}.navbar-expand .navbar-nav .nav-link{padding-right:var(--bs-navbar-nav-link-padding-x);padding-left:var(--bs-navbar-nav-link-padding-x)}.navbar-expand .navbar-nav-scroll{overflow:visible}.navbar-expand .navbar-collapse{display:flex !important;display:-webkit-flex !important;flex-basis:auto;-webkit-flex-basis:auto}.navbar-expand .navbar-toggler{display:none}.navbar-expand .offcanvas{position:static;z-index:auto;flex-grow:1;-webkit-flex-grow:1;width:auto !important;height:auto !important;visibility:visible !important;background-color:transparent !important;border:0 !important;transform:none !important;transition:none}.navbar-expand .offcanvas .offcanvas-header{display:none}.navbar-expand .offcanvas .offcanvas-body{display:flex;display:-webkit-flex;flex-grow:0;-webkit-flex-grow:0;padding:0;overflow-y:visible}.navbar-dark,.navbar[data-bs-theme="dark"]{--bs-navbar-color: #fff;--bs-navbar-hover-color: #2c3e50;--bs-navbar-disabled-color: rgba(255,255,255,0.25);--bs-navbar-active-color: #2c3e50;--bs-navbar-brand-color: #fff;--bs-navbar-brand-hover-color: #fff;--bs-navbar-toggler-border-color: rgba(255,255,255,0.1);--bs-navbar-toggler-icon-bg: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 30 30'%3e%3cpath stroke='rgba%28255,255,255,0.75%29' stroke-linecap='round' stroke-miterlimit='10' stroke-width='2' d='M4 7h22M4 15h22M4 23h22'/%3e%3c/svg%3e")}[data-bs-theme="dark"] .navbar-toggler-icon{--bs-navbar-toggler-icon-bg: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 30 30'%3e%3cpath stroke='rgba%28255,255,255,0.75%29' stroke-linecap='round' stroke-miterlimit='10' stroke-width='2' d='M4 7h22M4 15h22M4 23h22'/%3e%3c/svg%3e")}.card{--bs-card-spacer-y: 1rem;--bs-card-spacer-x: 1rem;--bs-card-title-spacer-y: .5rem;--bs-card-title-color: ;--bs-card-subtitle-color: ;--bs-card-border-width: var(--bs-border-width);--bs-card-border-color: var(--bs-border-color-translucent);--bs-card-border-radius: var(--bs-border-radius);--bs-card-box-shadow: ;--bs-card-inner-border-radius: calc(var(--bs-border-radius) - (var(--bs-border-width)));--bs-card-cap-padding-y: .5rem;--bs-card-cap-padding-x: 1rem;--bs-card-cap-bg: rgba(var(--bs-body-color-rgb), 0.03);--bs-card-cap-color: ;--bs-card-height: ;--bs-card-color: ;--bs-card-bg: var(--bs-body-bg);--bs-card-img-overlay-padding: 1rem;--bs-card-group-margin: .75rem;position:relative;display:flex;display:-webkit-flex;flex-direction:column;-webkit-flex-direction:column;min-width:0;height:var(--bs-card-height);color:var(--bs-body-color);word-wrap:break-word;background-color:var(--bs-card-bg);background-clip:border-box;border:var(--bs-card-border-width) solid var(--bs-card-border-color);border-radius:var(--bs-card-border-radius)}.card>hr{margin-right:0;margin-left:0}.card>.list-group{border-top:inherit;border-bottom:inherit}.card>.list-group:first-child{border-top-width:0;border-top-left-radius:var(--bs-card-inner-border-radius);border-top-right-radius:var(--bs-card-inner-border-radius)}.card>.list-group:last-child{border-bottom-width:0;border-bottom-right-radius:var(--bs-card-inner-border-radius);border-bottom-left-radius:var(--bs-card-inner-border-radius)}.card>.card-header+.list-group,.card>.list-group+.card-footer{border-top:0}.card-body{flex:1 1 auto;-webkit-flex:1 1 auto;padding:var(--bs-card-spacer-y) var(--bs-card-spacer-x);color:var(--bs-card-color)}.card-title{margin-bottom:var(--bs-card-title-spacer-y);color:var(--bs-card-title-color)}.card-subtitle{margin-top:calc(-.5 * var(--bs-card-title-spacer-y));margin-bottom:0;color:var(--bs-card-subtitle-color)}.card-text:last-child{margin-bottom:0}.card-link+.card-link{margin-left:var(--bs-card-spacer-x)}.card-header{padding:var(--bs-card-cap-padding-y) var(--bs-card-cap-padding-x);margin-bottom:0;color:var(--bs-card-cap-color);background-color:var(--bs-card-cap-bg);border-bottom:var(--bs-card-border-width) solid var(--bs-card-border-color)}.card-header:first-child{border-radius:var(--bs-card-inner-border-radius) var(--bs-card-inner-border-radius) 0 0}.card-footer{padding:var(--bs-card-cap-padding-y) var(--bs-card-cap-padding-x);color:var(--bs-card-cap-color);background-color:var(--bs-card-cap-bg);border-top:var(--bs-card-border-width) solid var(--bs-card-border-color)}.card-footer:last-child{border-radius:0 0 var(--bs-card-inner-border-radius) var(--bs-card-inner-border-radius)}.card-header-tabs{margin-right:calc(-.5 * var(--bs-card-cap-padding-x));margin-bottom:calc(-1 * var(--bs-card-cap-padding-y));margin-left:calc(-.5 * var(--bs-card-cap-padding-x));border-bottom:0}.card-header-tabs .nav-link.active{background-color:var(--bs-card-bg);border-bottom-color:var(--bs-card-bg)}.card-header-pills{margin-right:calc(-.5 * var(--bs-card-cap-padding-x));margin-left:calc(-.5 * var(--bs-card-cap-padding-x))}.card-img-overlay{position:absolute;top:0;right:0;bottom:0;left:0;padding:var(--bs-card-img-overlay-padding);border-radius:var(--bs-card-inner-border-radius)}.card-img,.card-img-top,.card-img-bottom{width:100%}.card-img,.card-img-top{border-top-left-radius:var(--bs-card-inner-border-radius);border-top-right-radius:var(--bs-card-inner-border-radius)}.card-img,.card-img-bottom{border-bottom-right-radius:var(--bs-card-inner-border-radius);border-bottom-left-radius:var(--bs-card-inner-border-radius)}.card-group>.card{margin-bottom:var(--bs-card-group-margin)}@media (min-width: 576px){.card-group{display:flex;display:-webkit-flex;flex-flow:row wrap;-webkit-flex-flow:row wrap}.card-group>.card{flex:1 0 0%;-webkit-flex:1 0 0%;margin-bottom:0}.card-group>.card+.card{margin-left:0;border-left:0}.card-group>.card:not(:last-child){border-top-right-radius:0;border-bottom-right-radius:0}.card-group>.card:not(:last-child) .card-img-top,.card-group>.card:not(:last-child) .card-header{border-top-right-radius:0}.card-group>.card:not(:last-child) .card-img-bottom,.card-group>.card:not(:last-child) .card-footer{border-bottom-right-radius:0}.card-group>.card:not(:first-child){border-top-left-radius:0;border-bottom-left-radius:0}.card-group>.card:not(:first-child) .card-img-top,.card-group>.card:not(:first-child) .card-header{border-top-left-radius:0}.card-group>.card:not(:first-child) .card-img-bottom,.card-group>.card:not(:first-child) .card-footer{border-bottom-left-radius:0}}.accordion{--bs-accordion-color: var(--bs-body-color);--bs-accordion-bg: var(--bs-body-bg);--bs-accordion-transition: color 0.15s ease-in-out,background-color 0.15s ease-in-out,border-color 0.15s ease-in-out,box-shadow 0.15s ease-in-out,border-radius 0.15s ease;--bs-accordion-border-color: var(--bs-border-color);--bs-accordion-border-width: var(--bs-border-width);--bs-accordion-border-radius: var(--bs-border-radius);--bs-accordion-inner-border-radius: calc(var(--bs-border-radius) - (var(--bs-border-width)));--bs-accordion-btn-padding-x: 1.25rem;--bs-accordion-btn-padding-y: 1rem;--bs-accordion-btn-color: var(--bs-body-color);--bs-accordion-btn-bg: var(--bs-accordion-bg);--bs-accordion-btn-icon: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 16 16' fill='%23212529'%3e%3cpath fill-rule='evenodd' d='M1.646 4.646a.5.5 0 0 1 .708 0L8 10.293l5.646-5.647a.5.5 0 0 1 .708.708l-6 6a.5.5 0 0 1-.708 0l-6-6a.5.5 0 0 1 0-.708z'/%3e%3c/svg%3e");--bs-accordion-btn-icon-width: 1.25rem;--bs-accordion-btn-icon-transform: rotate(-180deg);--bs-accordion-btn-icon-transition: transform 0.2s ease-in-out;--bs-accordion-btn-active-icon: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 16 16' fill='%23121920'%3e%3cpath fill-rule='evenodd' d='M1.646 4.646a.5.5 0 0 1 .708 0L8 10.293l5.646-5.647a.5.5 0 0 1 .708.708l-6 6a.5.5 0 0 1-.708 0l-6-6a.5.5 0 0 1 0-.708z'/%3e%3c/svg%3e");--bs-accordion-btn-focus-border-color: #969fa8;--bs-accordion-btn-focus-box-shadow: 0 0 0 .25rem rgba(44,62,80,0.25);--bs-accordion-body-padding-x: 1.25rem;--bs-accordion-body-padding-y: 1rem;--bs-accordion-active-color: var(--bs-primary-text-emphasis);--bs-accordion-active-bg: var(--bs-primary-bg-subtle)}.accordion-button{position:relative;display:flex;display:-webkit-flex;align-items:center;-webkit-align-items:center;width:100%;padding:var(--bs-accordion-btn-padding-y) var(--bs-accordion-btn-padding-x);font-size:1rem;color:var(--bs-accordion-btn-color);text-align:left;background-color:var(--bs-accordion-btn-bg);border:0;border-radius:0;overflow-anchor:none;transition:var(--bs-accordion-transition)}@media (prefers-reduced-motion: reduce){.accordion-button{transition:none}}.accordion-button:not(.collapsed){color:var(--bs-accordion-active-color);background-color:var(--bs-accordion-active-bg);box-shadow:inset 0 calc(-1 * var(--bs-accordion-border-width)) 0 var(--bs-accordion-border-color)}.accordion-button:not(.collapsed)::after{background-image:var(--bs-accordion-btn-active-icon);transform:var(--bs-accordion-btn-icon-transform)}.accordion-button::after{flex-shrink:0;-webkit-flex-shrink:0;width:var(--bs-accordion-btn-icon-width);height:var(--bs-accordion-btn-icon-width);margin-left:auto;content:"";background-image:var(--bs-accordion-btn-icon);background-repeat:no-repeat;background-size:var(--bs-accordion-btn-icon-width);transition:var(--bs-accordion-btn-icon-transition)}@media (prefers-reduced-motion: reduce){.accordion-button::after{transition:none}}.accordion-button:hover{z-index:2}.accordion-button:focus{z-index:3;border-color:var(--bs-accordion-btn-focus-border-color);outline:0;box-shadow:var(--bs-accordion-btn-focus-box-shadow)}.accordion-header{margin-bottom:0}.accordion-item{color:var(--bs-accordion-color);background-color:var(--bs-accordion-bg);border:var(--bs-accordion-border-width) solid var(--bs-accordion-border-color)}.accordion-item:first-of-type{border-top-left-radius:var(--bs-accordion-border-radius);border-top-right-radius:var(--bs-accordion-border-radius)}.accordion-item:first-of-type .accordion-button{border-top-left-radius:var(--bs-accordion-inner-border-radius);border-top-right-radius:var(--bs-accordion-inner-border-radius)}.accordion-item:not(:first-of-type){border-top:0}.accordion-item:last-of-type{border-bottom-right-radius:var(--bs-accordion-border-radius);border-bottom-left-radius:var(--bs-accordion-border-radius)}.accordion-item:last-of-type .accordion-button.collapsed{border-bottom-right-radius:var(--bs-accordion-inner-border-radius);border-bottom-left-radius:var(--bs-accordion-inner-border-radius)}.accordion-item:last-of-type .accordion-collapse{border-bottom-right-radius:var(--bs-accordion-border-radius);border-bottom-left-radius:var(--bs-accordion-border-radius)}.accordion-body{padding:var(--bs-accordion-body-padding-y) var(--bs-accordion-body-padding-x)}.accordion-flush .accordion-collapse{border-width:0}.accordion-flush .accordion-item{border-right:0;border-left:0;border-radius:0}.accordion-flush .accordion-item:first-child{border-top:0}.accordion-flush .accordion-item:last-child{border-bottom:0}.accordion-flush .accordion-item .accordion-button,.accordion-flush .accordion-item .accordion-button.collapsed{border-radius:0}[data-bs-theme="dark"] .accordion-button::after{--bs-accordion-btn-icon: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 16 16' fill='%23808b96'%3e%3cpath fill-rule='evenodd' d='M1.646 4.646a.5.5 0 0 1 .708 0L8 10.293l5.646-5.647a.5.5 0 0 1 .708.708l-6 6a.5.5 0 0 1-.708 0l-6-6a.5.5 0 0 1 0-.708z'/%3e%3c/svg%3e");--bs-accordion-btn-active-icon: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 16 16' fill='%23808b96'%3e%3cpath fill-rule='evenodd' d='M1.646 4.646a.5.5 0 0 1 .708 0L8 10.293l5.646-5.647a.5.5 0 0 1 .708.708l-6 6a.5.5 0 0 1-.708 0l-6-6a.5.5 0 0 1 0-.708z'/%3e%3c/svg%3e")}.breadcrumb{--bs-breadcrumb-padding-x: .75rem;--bs-breadcrumb-padding-y: .375rem;--bs-breadcrumb-margin-bottom: 1rem;--bs-breadcrumb-bg: ;--bs-breadcrumb-border-radius: .25rem;--bs-breadcrumb-divider-color: var(--bs-secondary-color);--bs-breadcrumb-item-padding-x: .5rem;--bs-breadcrumb-item-active-color: var(--bs-secondary-color);display:flex;display:-webkit-flex;flex-wrap:wrap;-webkit-flex-wrap:wrap;padding:var(--bs-breadcrumb-padding-y) var(--bs-breadcrumb-padding-x);margin-bottom:var(--bs-breadcrumb-margin-bottom);font-size:var(--bs-breadcrumb-font-size);list-style:none;background-color:var(--bs-breadcrumb-bg);border-radius:var(--bs-breadcrumb-border-radius)}.breadcrumb-item+.breadcrumb-item{padding-left:var(--bs-breadcrumb-item-padding-x)}.breadcrumb-item+.breadcrumb-item::before{float:left;padding-right:var(--bs-breadcrumb-item-padding-x);color:var(--bs-breadcrumb-divider-color);content:var(--bs-breadcrumb-divider, "/") /* rtl: var(--bs-breadcrumb-divider, "/") */}.breadcrumb-item.active{color:var(--bs-breadcrumb-item-active-color)}.pagination{--bs-pagination-padding-x: .75rem;--bs-pagination-padding-y: .375rem;--bs-pagination-font-size:1rem;--bs-pagination-color: #fff;--bs-pagination-bg: #18bc9c;--bs-pagination-border-width: 0;--bs-pagination-border-color: rgba(0,0,0,0);--bs-pagination-border-radius: var(--bs-border-radius);--bs-pagination-hover-color: #fff;--bs-pagination-hover-bg: #0f7864;--bs-pagination-hover-border-color: rgba(0,0,0,0);--bs-pagination-focus-color: var(--bs-link-hover-color);--bs-pagination-focus-bg: var(--bs-secondary-bg);--bs-pagination-focus-box-shadow: 0 0 0 .25rem rgba(44,62,80,0.25);--bs-pagination-active-color: #fff;--bs-pagination-active-bg: #0f7864;--bs-pagination-active-border-color: rgba(0,0,0,0);--bs-pagination-disabled-color: #ecf0f1;--bs-pagination-disabled-bg: #3be6c4;--bs-pagination-disabled-border-color: rgba(0,0,0,0);display:flex;display:-webkit-flex;padding-left:0;list-style:none}.page-link{position:relative;display:block;padding:var(--bs-pagination-padding-y) var(--bs-pagination-padding-x);font-size:var(--bs-pagination-font-size);color:var(--bs-pagination-color);text-decoration:none;-webkit-text-decoration:none;-moz-text-decoration:none;-ms-text-decoration:none;-o-text-decoration:none;background-color:var(--bs-pagination-bg);border:var(--bs-pagination-border-width) solid var(--bs-pagination-border-color);transition:color 0.15s ease-in-out,background-color 0.15s ease-in-out,border-color 0.15s ease-in-out,box-shadow 0.15s ease-in-out}@media (prefers-reduced-motion: reduce){.page-link{transition:none}}.page-link:hover{z-index:2;color:var(--bs-pagination-hover-color);background-color:var(--bs-pagination-hover-bg);border-color:var(--bs-pagination-hover-border-color)}.page-link:focus{z-index:3;color:var(--bs-pagination-focus-color);background-color:var(--bs-pagination-focus-bg);outline:0;box-shadow:var(--bs-pagination-focus-box-shadow)}.page-link.active,.active>.page-link{z-index:3;color:var(--bs-pagination-active-color);background-color:var(--bs-pagination-active-bg);border-color:var(--bs-pagination-active-border-color)}.page-link.disabled,.disabled>.page-link{color:var(--bs-pagination-disabled-color);pointer-events:none;background-color:var(--bs-pagination-disabled-bg);border-color:var(--bs-pagination-disabled-border-color)}.page-item:not(:first-child) .page-link{margin-left:calc(0 * -1)}.page-item:first-child .page-link{border-top-left-radius:var(--bs-pagination-border-radius);border-bottom-left-radius:var(--bs-pagination-border-radius)}.page-item:last-child .page-link{border-top-right-radius:var(--bs-pagination-border-radius);border-bottom-right-radius:var(--bs-pagination-border-radius)}.pagination-lg{--bs-pagination-padding-x: 1.5rem;--bs-pagination-padding-y: .75rem;--bs-pagination-font-size:1.25rem;--bs-pagination-border-radius: var(--bs-border-radius-lg)}.pagination-sm{--bs-pagination-padding-x: .5rem;--bs-pagination-padding-y: .25rem;--bs-pagination-font-size:.875rem;--bs-pagination-border-radius: var(--bs-border-radius-sm)}.badge{--bs-badge-padding-x: .65em;--bs-badge-padding-y: .35em;--bs-badge-font-size:.75em;--bs-badge-font-weight: 700;--bs-badge-color: #fff;--bs-badge-border-radius: var(--bs-border-radius);display:inline-block;padding:var(--bs-badge-padding-y) var(--bs-badge-padding-x);font-size:var(--bs-badge-font-size);font-weight:var(--bs-badge-font-weight);line-height:1;color:var(--bs-badge-color);text-align:center;white-space:nowrap;vertical-align:baseline;border-radius:var(--bs-badge-border-radius)}.badge:empty{display:none}.btn .badge{position:relative;top:-1px}.alert{--bs-alert-bg: transparent;--bs-alert-padding-x: 1rem;--bs-alert-padding-y: 1rem;--bs-alert-margin-bottom: 1rem;--bs-alert-color: inherit;--bs-alert-border-color: transparent;--bs-alert-border: var(--bs-border-width) solid var(--bs-alert-border-color);--bs-alert-border-radius: var(--bs-border-radius);--bs-alert-link-color: inherit;position:relative;padding:var(--bs-alert-padding-y) var(--bs-alert-padding-x);margin-bottom:var(--bs-alert-margin-bottom);color:var(--bs-alert-color);background-color:var(--bs-alert-bg);border:var(--bs-alert-border);border-radius:var(--bs-alert-border-radius)}.alert-heading{color:inherit}.alert-link{font-weight:700;color:var(--bs-alert-link-color)}.alert-dismissible{padding-right:3rem}.alert-dismissible .btn-close{position:absolute;top:0;right:0;z-index:2;padding:1.25rem 1rem}.alert-default{--bs-alert-color: var(--bs-default-text-emphasis);--bs-alert-bg: var(--bs-default-bg-subtle);--bs-alert-border-color: var(--bs-default-border-subtle);--bs-alert-link-color: var(--bs-default-text-emphasis)}.alert-primary{--bs-alert-color: var(--bs-primary-text-emphasis);--bs-alert-bg: var(--bs-primary-bg-subtle);--bs-alert-border-color: var(--bs-primary-border-subtle);--bs-alert-link-color: var(--bs-primary-text-emphasis)}.alert-secondary{--bs-alert-color: var(--bs-secondary-text-emphasis);--bs-alert-bg: var(--bs-secondary-bg-subtle);--bs-alert-border-color: var(--bs-secondary-border-subtle);--bs-alert-link-color: var(--bs-secondary-text-emphasis)}.alert-success{--bs-alert-color: var(--bs-success-text-emphasis);--bs-alert-bg: var(--bs-success-bg-subtle);--bs-alert-border-color: var(--bs-success-border-subtle);--bs-alert-link-color: var(--bs-success-text-emphasis)}.alert-info{--bs-alert-color: var(--bs-info-text-emphasis);--bs-alert-bg: var(--bs-info-bg-subtle);--bs-alert-border-color: var(--bs-info-border-subtle);--bs-alert-link-color: var(--bs-info-text-emphasis)}.alert-warning{--bs-alert-color: var(--bs-warning-text-emphasis);--bs-alert-bg: var(--bs-warning-bg-subtle);--bs-alert-border-color: var(--bs-warning-border-subtle);--bs-alert-link-color: var(--bs-warning-text-emphasis)}.alert-danger{--bs-alert-color: var(--bs-danger-text-emphasis);--bs-alert-bg: var(--bs-danger-bg-subtle);--bs-alert-border-color: var(--bs-danger-border-subtle);--bs-alert-link-color: var(--bs-danger-text-emphasis)}.alert-light{--bs-alert-color: var(--bs-light-text-emphasis);--bs-alert-bg: var(--bs-light-bg-subtle);--bs-alert-border-color: var(--bs-light-border-subtle);--bs-alert-link-color: var(--bs-light-text-emphasis)}.alert-dark{--bs-alert-color: var(--bs-dark-text-emphasis);--bs-alert-bg: var(--bs-dark-bg-subtle);--bs-alert-border-color: var(--bs-dark-border-subtle);--bs-alert-link-color: var(--bs-dark-text-emphasis)}@keyframes progress-bar-stripes{0%{background-position-x:1rem}}.progress,.progress-stacked{--bs-progress-height: 1rem;--bs-progress-font-size:.75rem;--bs-progress-bg: var(--bs-secondary-bg);--bs-progress-border-radius: var(--bs-border-radius);--bs-progress-box-shadow: var(--bs-box-shadow-inset);--bs-progress-bar-color: #fff;--bs-progress-bar-bg: #2c3e50;--bs-progress-bar-transition: width 0.6s ease;display:flex;display:-webkit-flex;height:var(--bs-progress-height);overflow:hidden;font-size:var(--bs-progress-font-size);background-color:var(--bs-progress-bg);border-radius:var(--bs-progress-border-radius)}.progress-bar{display:flex;display:-webkit-flex;flex-direction:column;-webkit-flex-direction:column;justify-content:center;-webkit-justify-content:center;overflow:hidden;color:var(--bs-progress-bar-color);text-align:center;white-space:nowrap;background-color:var(--bs-progress-bar-bg);transition:var(--bs-progress-bar-transition)}@media (prefers-reduced-motion: reduce){.progress-bar{transition:none}}.progress-bar-striped{background-image:linear-gradient(45deg, rgba(255,255,255,0.15) 25%, transparent 25%, transparent 50%, rgba(255,255,255,0.15) 50%, rgba(255,255,255,0.15) 75%, transparent 75%, transparent);background-size:var(--bs-progress-height) var(--bs-progress-height)}.progress-stacked>.progress{overflow:visible}.progress-stacked>.progress>.progress-bar{width:100%}.progress-bar-animated{animation:1s linear infinite progress-bar-stripes}@media (prefers-reduced-motion: reduce){.progress-bar-animated{animation:none}}.list-group{--bs-list-group-color: var(--bs-body-color);--bs-list-group-bg: var(--bs-body-bg);--bs-list-group-border-color: var(--bs-border-color);--bs-list-group-border-width: var(--bs-border-width);--bs-list-group-border-radius: var(--bs-border-radius);--bs-list-group-item-padding-x: 1rem;--bs-list-group-item-padding-y: .5rem;--bs-list-group-action-color: var(--bs-secondary-color);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: #ecf0f1;--bs-list-group-action-active-color: var(--bs-body-color);--bs-list-group-action-active-bg: var(--bs-secondary-bg);--bs-list-group-disabled-color: var(--bs-secondary-color);--bs-list-group-disabled-bg: 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576px){.list-group-horizontal-sm{flex-direction:row;-webkit-flex-direction:row}.list-group-horizontal-sm>.list-group-item:first-child:not(:last-child){border-bottom-left-radius:var(--bs-list-group-border-radius);border-top-right-radius:0}.list-group-horizontal-sm>.list-group-item:last-child:not(:first-child){border-top-right-radius:var(--bs-list-group-border-radius);border-bottom-left-radius:0}.list-group-horizontal-sm>.list-group-item.active{margin-top:0}.list-group-horizontal-sm>.list-group-item+.list-group-item{border-top-width:var(--bs-list-group-border-width);border-left-width:0}.list-group-horizontal-sm>.list-group-item+.list-group-item.active{margin-left:calc(-1 * var(--bs-list-group-border-width));border-left-width:var(--bs-list-group-border-width)}}@media (min-width: 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992px){.list-group-horizontal-lg{flex-direction:row;-webkit-flex-direction:row}.list-group-horizontal-lg>.list-group-item:first-child:not(:last-child){border-bottom-left-radius:var(--bs-list-group-border-radius);border-top-right-radius:0}.list-group-horizontal-lg>.list-group-item:last-child:not(:first-child){border-top-right-radius:var(--bs-list-group-border-radius);border-bottom-left-radius:0}.list-group-horizontal-lg>.list-group-item.active{margin-top:0}.list-group-horizontal-lg>.list-group-item+.list-group-item{border-top-width:var(--bs-list-group-border-width);border-left-width:0}.list-group-horizontal-lg>.list-group-item+.list-group-item.active{margin-left:calc(-1 * var(--bs-list-group-border-width));border-left-width:var(--bs-list-group-border-width)}}@media (min-width: 1200px){.list-group-horizontal-xl{flex-direction:row;-webkit-flex-direction:row}.list-group-horizontal-xl>.list-group-item:first-child:not(:last-child){border-bottom-left-radius:var(--bs-list-group-border-radius);border-top-right-radius:0}.list-group-horizontal-xl>.list-group-item:last-child:not(:first-child){border-top-right-radius:var(--bs-list-group-border-radius);border-bottom-left-radius:0}.list-group-horizontal-xl>.list-group-item.active{margin-top:0}.list-group-horizontal-xl>.list-group-item+.list-group-item{border-top-width:var(--bs-list-group-border-width);border-left-width:0}.list-group-horizontal-xl>.list-group-item+.list-group-item.active{margin-left:calc(-1 * var(--bs-list-group-border-width));border-left-width:var(--bs-list-group-border-width)}}@media (min-width: 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var(--bs-list-group-border-width)}.list-group-flush>.list-group-item:last-child{border-bottom-width:0}.list-group-item-default{--bs-list-group-color: var(--bs-default-text-emphasis);--bs-list-group-bg: var(--bs-default-bg-subtle);--bs-list-group-border-color: var(--bs-default-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-default-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-default-border-subtle);--bs-list-group-active-color: var(--bs-default-bg-subtle);--bs-list-group-active-bg: var(--bs-default-text-emphasis);--bs-list-group-active-border-color: var(--bs-default-text-emphasis)}.list-group-item-primary{--bs-list-group-color: var(--bs-primary-text-emphasis);--bs-list-group-bg: var(--bs-primary-bg-subtle);--bs-list-group-border-color: var(--bs-primary-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-primary-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-primary-border-subtle);--bs-list-group-active-color: var(--bs-primary-bg-subtle);--bs-list-group-active-bg: var(--bs-primary-text-emphasis);--bs-list-group-active-border-color: var(--bs-primary-text-emphasis)}.list-group-item-secondary{--bs-list-group-color: var(--bs-secondary-text-emphasis);--bs-list-group-bg: var(--bs-secondary-bg-subtle);--bs-list-group-border-color: var(--bs-secondary-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-secondary-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-secondary-border-subtle);--bs-list-group-active-color: var(--bs-secondary-bg-subtle);--bs-list-group-active-bg: var(--bs-secondary-text-emphasis);--bs-list-group-active-border-color: var(--bs-secondary-text-emphasis)}.list-group-item-success{--bs-list-group-color: var(--bs-success-text-emphasis);--bs-list-group-bg: var(--bs-success-bg-subtle);--bs-list-group-border-color: var(--bs-success-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-success-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-success-border-subtle);--bs-list-group-active-color: var(--bs-success-bg-subtle);--bs-list-group-active-bg: var(--bs-success-text-emphasis);--bs-list-group-active-border-color: var(--bs-success-text-emphasis)}.list-group-item-info{--bs-list-group-color: var(--bs-info-text-emphasis);--bs-list-group-bg: var(--bs-info-bg-subtle);--bs-list-group-border-color: var(--bs-info-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-info-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-info-border-subtle);--bs-list-group-active-color: var(--bs-info-bg-subtle);--bs-list-group-active-bg: var(--bs-info-text-emphasis);--bs-list-group-active-border-color: var(--bs-info-text-emphasis)}.list-group-item-warning{--bs-list-group-color: var(--bs-warning-text-emphasis);--bs-list-group-bg: var(--bs-warning-bg-subtle);--bs-list-group-border-color: var(--bs-warning-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-warning-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-warning-border-subtle);--bs-list-group-active-color: var(--bs-warning-bg-subtle);--bs-list-group-active-bg: var(--bs-warning-text-emphasis);--bs-list-group-active-border-color: var(--bs-warning-text-emphasis)}.list-group-item-danger{--bs-list-group-color: var(--bs-danger-text-emphasis);--bs-list-group-bg: var(--bs-danger-bg-subtle);--bs-list-group-border-color: var(--bs-danger-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-danger-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-danger-border-subtle);--bs-list-group-active-color: var(--bs-danger-bg-subtle);--bs-list-group-active-bg: var(--bs-danger-text-emphasis);--bs-list-group-active-border-color: var(--bs-danger-text-emphasis)}.list-group-item-light{--bs-list-group-color: var(--bs-light-text-emphasis);--bs-list-group-bg: var(--bs-light-bg-subtle);--bs-list-group-border-color: var(--bs-light-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-light-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-light-border-subtle);--bs-list-group-active-color: var(--bs-light-bg-subtle);--bs-list-group-active-bg: var(--bs-light-text-emphasis);--bs-list-group-active-border-color: var(--bs-light-text-emphasis)}.list-group-item-dark{--bs-list-group-color: var(--bs-dark-text-emphasis);--bs-list-group-bg: var(--bs-dark-bg-subtle);--bs-list-group-border-color: var(--bs-dark-border-subtle);--bs-list-group-action-hover-color: var(--bs-emphasis-color);--bs-list-group-action-hover-bg: var(--bs-dark-border-subtle);--bs-list-group-action-active-color: var(--bs-emphasis-color);--bs-list-group-action-active-bg: var(--bs-dark-border-subtle);--bs-list-group-active-color: var(--bs-dark-bg-subtle);--bs-list-group-active-bg: var(--bs-dark-text-emphasis);--bs-list-group-active-border-color: var(--bs-dark-text-emphasis)}.btn-close{--bs-btn-close-color: #fff;--bs-btn-close-bg: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 16 16' fill='%23fff'%3e%3cpath d='M.293.293a1 1 0 0 1 1.414 0L8 6.586 14.293.293a1 1 0 1 1 1.414 1.414L9.414 8l6.293 6.293a1 1 0 0 1-1.414 1.414L8 9.414l-6.293 6.293a1 1 0 0 1-1.414-1.414L6.586 8 .293 1.707a1 1 0 0 1 0-1.414z'/%3e%3c/svg%3e");--bs-btn-close-opacity: .4;--bs-btn-close-hover-opacity: 1;--bs-btn-close-focus-shadow: 0 0 0 .25rem rgba(44,62,80,0.25);--bs-btn-close-focus-opacity: 1;--bs-btn-close-disabled-opacity: .25;--bs-btn-close-white-filter: invert(1) grayscale(100%) brightness(200%);box-sizing:content-box;width:1em;height:1em;padding:.25em .25em;color:var(--bs-btn-close-color);background:transparent var(--bs-btn-close-bg) center/1em auto no-repeat;border:0;border-radius:.375rem;opacity:var(--bs-btn-close-opacity)}.btn-close:hover{color:var(--bs-btn-close-color);text-decoration:none;opacity:var(--bs-btn-close-hover-opacity)}.btn-close:focus{outline:0;box-shadow:var(--bs-btn-close-focus-shadow);opacity:var(--bs-btn-close-focus-opacity)}.btn-close:disabled,.btn-close.disabled{pointer-events:none;user-select:none;-webkit-user-select:none;-moz-user-select:none;-ms-user-select:none;-o-user-select:none;opacity:var(--bs-btn-close-disabled-opacity)}.btn-close-white{filter:var(--bs-btn-close-white-filter)}[data-bs-theme="dark"] .btn-close{filter:var(--bs-btn-close-white-filter)}.toast{--bs-toast-zindex: 1090;--bs-toast-padding-x: .75rem;--bs-toast-padding-y: .5rem;--bs-toast-spacing: 1.5rem;--bs-toast-max-width: 350px;--bs-toast-font-size:.875rem;--bs-toast-color: ;--bs-toast-bg: rgba(var(--bs-body-bg-rgb), 0.85);--bs-toast-border-width: var(--bs-border-width);--bs-toast-border-color: var(--bs-border-color-translucent);--bs-toast-border-radius: var(--bs-border-radius);--bs-toast-box-shadow: var(--bs-box-shadow);--bs-toast-header-color: var(--bs-secondary-color);--bs-toast-header-bg: rgba(var(--bs-body-bg-rgb), 0.85);--bs-toast-header-border-color: var(--bs-border-color-translucent);width:var(--bs-toast-max-width);max-width:100%;font-size:var(--bs-toast-font-size);color:var(--bs-toast-color);pointer-events:auto;background-color:var(--bs-toast-bg);background-clip:padding-box;border:var(--bs-toast-border-width) solid var(--bs-toast-border-color);box-shadow:var(--bs-toast-box-shadow);border-radius:var(--bs-toast-border-radius)}.toast.showing{opacity:0}.toast:not(.show){display:none}.toast-container{--bs-toast-zindex: 1090;position:absolute;z-index:var(--bs-toast-zindex);width:max-content;width:-webkit-max-content;width:-moz-max-content;width:-ms-max-content;width:-o-max-content;max-width:100%;pointer-events:none}.toast-container>:not(:last-child){margin-bottom:var(--bs-toast-spacing)}.toast-header{display:flex;display:-webkit-flex;align-items:center;-webkit-align-items:center;padding:var(--bs-toast-padding-y) var(--bs-toast-padding-x);color:var(--bs-toast-header-color);background-color:var(--bs-toast-header-bg);background-clip:padding-box;border-bottom:var(--bs-toast-border-width) solid var(--bs-toast-header-border-color);border-top-left-radius:calc(var(--bs-toast-border-radius) - var(--bs-toast-border-width));border-top-right-radius:calc(var(--bs-toast-border-radius) - var(--bs-toast-border-width))}.toast-header .btn-close{margin-right:calc(-.5 * var(--bs-toast-padding-x));margin-left:var(--bs-toast-padding-x)}.toast-body{padding:var(--bs-toast-padding-x);word-wrap:break-word}.modal{--bs-modal-zindex: 1055;--bs-modal-width: 500px;--bs-modal-padding: 1rem;--bs-modal-margin: .5rem;--bs-modal-color: ;--bs-modal-bg: var(--bs-body-bg);--bs-modal-border-color: var(--bs-border-color-translucent);--bs-modal-border-width: var(--bs-border-width);--bs-modal-border-radius: var(--bs-border-radius-lg);--bs-modal-box-shadow: 0 0.125rem 0.25rem rgba(0,0,0,0.075);--bs-modal-inner-border-radius: calc(var(--bs-border-radius-lg) - (var(--bs-border-width)));--bs-modal-header-padding-x: 1rem;--bs-modal-header-padding-y: 1rem;--bs-modal-header-padding: 1rem 1rem;--bs-modal-header-border-color: var(--bs-border-color);--bs-modal-header-border-width: var(--bs-border-width);--bs-modal-title-line-height: 1.5;--bs-modal-footer-gap: .5rem;--bs-modal-footer-bg: ;--bs-modal-footer-border-color: var(--bs-border-color);--bs-modal-footer-border-width: 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a.nav-link.active{background-color:#e9e9ea;color:#000}#toc>.nav .nav a.nav-link{margin-left:0.5rem}#toc>.nav .nav{display:none !important}#toc>.nav a.active+.nav{display:flex !important}footer{margin:1rem 0 1rem 0;font-size:.875em;border-top:1px solid #dee2e6;background:rgba(0,0,0,0);color:#4d5154;display:flex;column-gap:1rem}@media (max-width: 575.98px){footer{flex-direction:column}}@media (min-width: 576px){footer .pkgdown-footer-right{text-align:right}}footer div{flex:1 1 auto}html,body{height:100%}body>.container{min-height:100%;display:flex;flex-direction:column}body>.container .row{flex:1 0 auto}::selection{background-color:#d5d8dc}main img{max-width:100%;height:auto}main table{display:block;overflow:auto}body{font-display:fallback}.page-header{border-bottom:1px solid #dee2e6;padding-bottom:0.5rem;margin-bottom:0.5rem;margin-top:1.5rem}dd{margin-left:1.5rem}summary{margin-bottom:0.5rem}details{margin-bottom:1rem}.html-widget{margin-bottom:1rem}a.anchor{display:none;margin-left:5px;width:Min(0.9em, 20px);height:Min(0.9em, 20px);background-image:url(../../link.svg);background-repeat:no-repeat;background-size:Min(0.9em, 20px) Min(0.9em, 20px);background-position:center center}h2:hover .anchor,.h2:hover .anchor,h3:hover .anchor,.h3:hover .anchor,h4:hover .anchor,.h4:hover .anchor,h5:hover .anchor,.h5:hover .anchor,h6:hover .anchor,.h6:hover .anchor{display:inline-block}.orcid{color:#A6CE39;margin-right:4px}.fab{font-family:"Font Awesome 5 Brands" !important}img.logo{float:right;width:100px;margin-left:30px}.template-home img.logo{width:120px}@media (max-width: 575.98px){img.logo{width:80px}}@media (min-width: 576px){.page-header{min-height:88px}.template-home .page-header{min-height:104px}}.line-block{margin-bottom:1rem}.template-reference-index dt{font-weight:normal}.template-reference-index code{word-wrap:normal}.icon{float:right}.icon img{width:40px}a.footnote-ref{cursor:pointer}.popover{width:Min(100vw, 32rem);font-size:0.9rem;box-shadow:4px 4px 8px rgba(0,0,0,0.3)}.popover-body{padding:0.75rem}.popover-body p:last-child{margin-bottom:0}.tab-content{padding:1rem}.tabset-pills .tab-content{border:solid 1px #e5e5e5}.tab-content{display:flex}.tab-content>.tab-pane{display:block;visibility:hidden;margin-right:-100%;width:100%}.tab-content>.active{visibility:visible}div.csl-entry{clear:both}.hanging-indent div.csl-entry{margin-left:2em;text-indent:-2em}div.csl-left-margin{min-width:2em;float:left}div.csl-right-inline{margin-left:2em;padding-left:1em}div.csl-indent{margin-left:2em}pre,pre code{word-wrap:normal}code{overflow-wrap:break-word}.hasCopyButton{position:relative}.btn-copy-ex{position:absolute;right:5px;top:5px;visibility:hidden}.hasCopyButton:hover button.btn-copy-ex{visibility:visible}pre{padding:1rem 0.5rem}@media (max-width: 575.98px){div>div>pre{margin-left:calc(var(--bs-gutter-x) * -.5);margin-right:calc(var(--bs-gutter-x) * -.5);border-radius:0;padding-left:1rem;padding-right:1rem}.btn-copy-ex{right:calc(var(--bs-gutter-x) * -.5 + 5px)}}code a:any-link{color:inherit;text-decoration-color:#95a5a6}pre code{padding:0;background:transparent}pre code .error,pre code .warning{font-weight:bolder}pre .img img,pre .r-plt img{margin:5px 0;background-color:#fff}@media print{code a:link:after,code a:visited:after{content:""}}a.sourceLine:hover{text-decoration:none}mark,.mark{background:linear-gradient(-100deg, rgba(52,152,219,0.2), rgba(52,152,219,0.7) 95%, rgba(52,152,219,0.1))}.algolia-autocomplete .aa-hint{color:#212529}.algolia-autocomplete .aa-dropdown-menu{width:Max(100%, 20rem);background-color:#fff;border:1px solid var(--bs-border-color);margin-top:2px;max-height:50vh;overflow-y:auto}.algolia-autocomplete .aa-dropdown-menu .aa-suggestion{cursor:pointer;padding:5px 4px;border-bottom:1px #ecf0f1 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diff --git a/deps/bootstrap-5.3.1/font.css b/deps/bootstrap-5.3.1/font.css
index fa85d55..02b33a1 100644
--- a/deps/bootstrap-5.3.1/font.css
+++ b/deps/bootstrap-5.3.1/font.css
@@ -1,1452 +1,54 @@
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtE6F15M.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWvU6F15M.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtU6F15M.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuk6F15M.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWu06F15M.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWxU6F15M.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqW106F15M.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtk6F15M.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWt06F15M.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuU6F.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtE6F15M.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWvU6F15M.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtU6F15M.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuk6F15M.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWu06F15M.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWxU6F15M.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqW106F15M.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtk6F15M.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWt06F15M.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuU6F.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtE6F15M.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWvU6F15M.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtU6F15M.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuk6F15M.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWu06F15M.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWxU6F15M.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqW106F15M.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtk6F15M.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWt06F15M.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuU6F.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtE6F15M.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWvU6F15M.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtU6F15M.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuk6F15M.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWu06F15M.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWxU6F15M.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqW106F15M.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtk6F15M.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWt06F15M.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuU6F.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtE6F15M.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWvU6F15M.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtU6F15M.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuk6F15M.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWu06F15M.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWxU6F15M.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqW106F15M.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtk6F15M.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWt06F15M.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuU6F.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtE6F15M.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWvU6F15M.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtU6F15M.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuk6F15M.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWu06F15M.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWxU6F15M.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqW106F15M.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWtk6F15M.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWt06F15M.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: italic;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memtYaGs126MiZpBA-UFUIcVXSCEkx2cmqvXlWqWuU6F.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSKmu1aB.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSumu1aB.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSOmu1aB.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSymu1aB.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS2mu1aB.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTVOmu1aB.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTUGmu1aB.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSCmu1aB.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSGmu1aB.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 300;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS-muw.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSKmu1aB.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSumu1aB.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSOmu1aB.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSymu1aB.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS2mu1aB.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTVOmu1aB.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTUGmu1aB.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSCmu1aB.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSGmu1aB.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 400;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS-muw.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSKmu1aB.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSumu1aB.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSOmu1aB.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSymu1aB.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS2mu1aB.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTVOmu1aB.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTUGmu1aB.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSCmu1aB.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSGmu1aB.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 500;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS-muw.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSKmu1aB.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSumu1aB.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSOmu1aB.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSymu1aB.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS2mu1aB.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTVOmu1aB.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTUGmu1aB.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSCmu1aB.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSGmu1aB.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 600;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS-muw.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSKmu1aB.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSumu1aB.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSOmu1aB.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSymu1aB.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS2mu1aB.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTVOmu1aB.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTUGmu1aB.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSCmu1aB.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSGmu1aB.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 700;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS-muw.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSKmu1aB.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSumu1aB.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSOmu1aB.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSymu1aB.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* hebrew */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS2mu1aB.woff2) format('woff2');
-  unicode-range: U+0590-05FF, U+200C-2010, U+20AA, U+25CC, U+FB1D-FB4F;
-}
-/* math */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTVOmu1aB.woff2) format('woff2');
-  unicode-range: U+0302-0303, U+0305, U+0307-0308, U+0330, U+0391-03A1, U+03A3-03A9, U+03B1-03C9, U+03D1, U+03D5-03D6, U+03F0-03F1, U+03F4-03F5, U+2034-2037, U+2057, U+20D0-20DC, U+20E1, U+20E5-20EF, U+2102, U+210A-210E, U+2110-2112, U+2115, U+2119-211D, U+2124, U+2128, U+212C-212D, U+212F-2131, U+2133-2138, U+213C-2140, U+2145-2149, U+2190, U+2192, U+2194-21AE, U+21B0-21E5, U+21F1-21F2, U+21F4-2211, U+2213-2214, U+2216-22FF, U+2308-230B, U+2310, U+2319, U+231C-2321, U+2336-237A, U+237C, U+2395, U+239B-23B6, U+23D0, U+23DC-23E1, U+2474-2475, U+25AF, U+25B3, U+25B7, U+25BD, U+25C1, U+25CA, U+25CC, U+25FB, U+266D-266F, U+27C0-27FF, U+2900-2AFF, U+2B0E-2B11, U+2B30-2B4C, U+2BFE, U+FF5B, U+FF5D, U+1D400-1D7FF, U+1EE00-1EEFF;
-}
-/* symbols */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTUGmu1aB.woff2) format('woff2');
-  unicode-range: U+0001-000C, U+000E-001F, U+007F-009F, U+20DD-20E0, U+20E2-20E4, U+2150-218F, U+2190, U+2192, U+2194-2199, U+21AF, U+21E6-21F0, U+21F3, U+2218-2219, U+2299, U+22C4-22C6, U+2300-243F, U+2440-244A, U+2460-24FF, U+25A0-27BF, U+2800-28FF, U+2921-2922, U+2981, U+29BF, U+29EB, U+2B00-2BFF, U+4DC0-4DFF, U+FFF9-FFFB, U+10140-1018E, U+10190-1019C, U+101A0, U+101D0-101FD, U+102E0-102FB, U+10E60-10E7E, U+1D2C0-1D2D3, U+1D2E0-1D37F, U+1F000-1F0FF, U+1F100-1F1AD, U+1F1E6-1F1FF, U+1F30D-1F30F, U+1F315, U+1F31C, U+1F31E, U+1F320-1F32C, U+1F336, U+1F378, U+1F37D, U+1F382, U+1F393-1F39F, U+1F3A7-1F3A8, U+1F3AC-1F3AF, U+1F3C2, U+1F3C4-1F3C6, U+1F3CA-1F3CE, U+1F3D4-1F3E0, U+1F3ED, U+1F3F1-1F3F3, U+1F3F5-1F3F7, U+1F408, U+1F415, U+1F41F, U+1F426, U+1F43F, U+1F441-1F442, U+1F444, U+1F446-1F449, U+1F44C-1F44E, U+1F453, U+1F46A, U+1F47D, U+1F4A3, U+1F4B0, U+1F4B3, U+1F4B9, U+1F4BB, U+1F4BF, U+1F4C8-1F4CB, U+1F4D6, U+1F4DA, U+1F4DF, U+1F4E3-1F4E6, U+1F4EA-1F4ED, U+1F4F7, U+1F4F9-1F4FB, U+1F4FD-1F4FE, U+1F503, U+1F507-1F50B, U+1F50D, U+1F512-1F513, U+1F53E-1F54A, U+1F54F-1F5FA, U+1F610, U+1F650-1F67F, U+1F687, U+1F68D, U+1F691, U+1F694, U+1F698, U+1F6AD, U+1F6B2, U+1F6B9-1F6BA, U+1F6BC, U+1F6C6-1F6CF, U+1F6D3-1F6D7, U+1F6E0-1F6EA, U+1F6F0-1F6F3, U+1F6F7-1F6FC, U+1F700-1F7FF, U+1F800-1F80B, U+1F810-1F847, U+1F850-1F859, U+1F860-1F887, U+1F890-1F8AD, U+1F8B0-1F8B1, U+1F900-1F90B, U+1F93B, U+1F946, U+1F984, U+1F996, U+1F9E9, U+1FA00-1FA6F, U+1FA70-1FA7C, U+1FA80-1FA88, U+1FA90-1FABD, U+1FABF-1FAC5, U+1FACE-1FADB, U+1FAE0-1FAE8, U+1FAF0-1FAF8, U+1FB00-1FBFF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSCmu1aB.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTSGmu1aB.woff2) format('woff2');
-  unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
-}
-/* latin */
-@font-face {
-  font-family: 'Open Sans';
-  font-style: normal;
-  font-weight: 800;
-  font-stretch: 100%;
-  font-display: swap;
-  src: url(fonts/memvYaGs126MiZpBA-UvWbX2vVnXBbObj2OVTS-muw.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 400;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvZlMIXxw.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 400;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvQlMIXxw.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 400;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvYlMIXxw.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 400;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvXlMIXxw.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 400;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvblMIXxw.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
 /* latin-ext */
 @font-face {
-  font-family: 'Source Code Pro';
+  font-family: 'Lato';
   font-style: italic;
   font-weight: 400;
   font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvalMIXxw.woff2) format('woff2');
+  src: url(fonts/S6u8w4BMUTPHjxsAUi-qJCY.woff2) format('woff2');
   unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
 }
 /* latin */
 @font-face {
-  font-family: 'Source Code Pro';
+  font-family: 'Lato';
   font-style: italic;
   font-weight: 400;
   font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvUlMI.woff2) format('woff2');
-  unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
-}
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvZlMIXxw.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvQlMIXxw.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvYlMIXxw.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvXlMIXxw.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvblMIXxw.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
-/* latin-ext */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvalMIXxw.woff2) format('woff2');
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-}
-/* latin */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: italic;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_QiYsKILxRpg3hIP6sJ7fM7PqlONvUlMI.woff2) format('woff2');
+  src: url(fonts/S6u8w4BMUTPHjxsAXC-q.woff2) format('woff2');
   unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
 }
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: normal;
-  font-weight: 400;
-  font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlMOvWjMY.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: normal;
-  font-weight: 400;
-  font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlOevWjMY.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: normal;
-  font-weight: 400;
-  font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlMevWjMY.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: normal;
-  font-weight: 400;
-  font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlPuvWjMY.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: normal;
-  font-weight: 400;
-  font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlMuvWjMY.woff2) format('woff2');
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-}
 /* latin-ext */
 @font-face {
-  font-family: 'Source Code Pro';
+  font-family: 'Lato';
   font-style: normal;
   font-weight: 400;
   font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlM-vWjMY.woff2) format('woff2');
+  src: url(fonts/S6uyw4BMUTPHjxAwXjeu.woff2) format('woff2');
   unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
 }
 /* latin */
 @font-face {
-  font-family: 'Source Code Pro';
+  font-family: 'Lato';
   font-style: normal;
   font-weight: 400;
   font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlPevW.woff2) format('woff2');
+  src: url(fonts/S6uyw4BMUTPHjx4wXg.woff2) format('woff2');
   unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
 }
-/* cyrillic-ext */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: normal;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlMOvWjMY.woff2) format('woff2');
-  unicode-range: U+0460-052F, U+1C80-1C88, U+20B4, U+2DE0-2DFF, U+A640-A69F, U+FE2E-FE2F;
-}
-/* cyrillic */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: normal;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlOevWjMY.woff2) format('woff2');
-  unicode-range: U+0301, U+0400-045F, U+0490-0491, U+04B0-04B1, U+2116;
-}
-/* greek-ext */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: normal;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlMevWjMY.woff2) format('woff2');
-  unicode-range: U+1F00-1FFF;
-}
-/* greek */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: normal;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlPuvWjMY.woff2) format('woff2');
-  unicode-range: U+0370-0377, U+037A-037F, U+0384-038A, U+038C, U+038E-03A1, U+03A3-03FF;
-}
-/* vietnamese */
-@font-face {
-  font-family: 'Source Code Pro';
-  font-style: normal;
-  font-weight: 600;
-  font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlMuvWjMY.woff2) format('woff2');
-  unicode-range: U+0102-0103, U+0110-0111, U+0128-0129, U+0168-0169, U+01A0-01A1, U+01AF-01B0, U+0300-0301, U+0303-0304, U+0308-0309, U+0323, U+0329, U+1EA0-1EF9, U+20AB;
-}
 /* latin-ext */
 @font-face {
-  font-family: 'Source Code Pro';
+  font-family: 'Lato';
   font-style: normal;
-  font-weight: 600;
+  font-weight: 700;
   font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlM-vWjMY.woff2) format('woff2');
+  src: url(fonts/S6u9w4BMUTPHh6UVSwaPGR_p.woff2) format('woff2');
   unicode-range: U+0100-02AF, U+0304, U+0308, U+0329, U+1E00-1E9F, U+1EF2-1EFF, U+2020, U+20A0-20AB, U+20AD-20C0, U+2113, U+2C60-2C7F, U+A720-A7FF;
 }
 /* latin */
 @font-face {
-  font-family: 'Source Code Pro';
+  font-family: 'Lato';
   font-style: normal;
-  font-weight: 600;
+  font-weight: 700;
   font-display: swap;
-  src: url(fonts/HI_SiYsKILxRpg3hIP6sJ7fM7PqlPevW.woff2) format('woff2');
+  src: url(fonts/S6u9w4BMUTPHh6UVSwiPGQ.woff2) format('woff2');
   unicode-range: U+0000-00FF, U+0131, U+0152-0153, U+02BB-02BC, U+02C6, U+02DA, U+02DC, U+0304, U+0308, U+0329, U+2000-206F, U+2074, U+20AC, U+2122, U+2191, U+2193, U+2212, U+2215, U+FEFF, U+FFFD;
 }
diff --git a/extra.css b/extra.css
new file mode 100644
index 0000000..8df263e
--- /dev/null
+++ b/extra.css
@@ -0,0 +1,8 @@
+.dropdown-header {
+  font-size: 1.2rem;
+  color: #494646;
+  font-weight: 700;
+}
+.text-muted {
+  color: var(--bs-navbar-brand-color) !important;
+}
diff --git a/favicon-16x16.png b/favicon-16x16.png
index 2452829a17f29c52ef7304b76a6f004ff502265f..ff1a90772103470563ce262d1b673d9c5880a05b 100644
GIT binary patch
delta 96
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l8c~vxSdwa$o1c=IR>@#wU}U0eV4{nmLFQ`iipl1z`2bEB8$JL4

delta 96
zcmZ3+y^MRqT4oLoHZys)yx5@4TbXSb-3%;349u)dO{|O!wG9lcfav*-w+svnswJ)w
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diff --git a/favicon-32x32.png b/favicon-32x32.png
index ca01c2dbf9ef1582795358f770fa77cd14eea0d1..40cf04405358d2ffeb3dfbb048d2d0e4a692eb32 100644
GIT binary patch
delta 70
zcmaDa@m^v=6$dw)vR3Kc3*8%=EVxAt4MPmftc*>qOpLS*46F<cViL}GPCm~qgDInH
KTW&guCm#SCrxcO^

delta 70
zcmaDa@m^v=6$b~KnZgE+g8Yq57Tlr+79j>^R;DIa#zxu(237_J-296QCZFe)!IY^A
Kk~%YqCm#UD$rC~V

diff --git a/index.html b/index.html
index 846edaa..a8c1e17 100644
--- a/index.html
+++ b/index.html
@@ -17,7 +17,8 @@
 <link href="deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet">
 <script src="deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous">
 <link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous">
-<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="pkgdown.js"></script><meta property="og:title" content="Facilitating AMNOG style analysis pipelines">
+<!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="pkgdown.js"></script><link href="extra.css" rel="stylesheet">
+<meta property="og:title" content="Facilitating AMNOG style analysis pipelines">
 <meta property="og:description" content="What the package does (one paragraph).">
 <meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png">
 <!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
@@ -29,11 +30,11 @@
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -43,42 +44,38 @@
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto">
 <li class="nav-item">
-  <a class="nav-link" href="articles/ramnog.html">Get started</a>
-</li>
-<li class="nav-item">
-  <a class="nav-link" href="reference/index.html">Reference</a>
+  <a class="nav-link" href="articles/ramnog.html">Quick start</a>
 </li>
 <li class="nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul>
@@ -86,7 +83,14 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="search.json" id="search-input" placeholder="Search for" autocomplete="off">
 </form>
 
-      <ul class="navbar-nav"></ul>
+      <ul class="navbar-nav">
+<li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul>
 </div>
 
     
@@ -99,17 +103,24 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
 <a class="anchor" aria-label="anchor" href="#ramnog-"></a>
 </h1>
 </div>
-<p>The {ramnog} package is a collection of packages for setting up pipelines for AMNOG-style HTA analyses. The aim of {ramnog} is to enable statisticians/programmers to set up an AMNOG-type analyses with minimal familiarity with <code>R</code>.</p>
+</div>
+<div class="section level1">
+<h1 id="r-packages-for-amnog-analyses-">R packages for AMNOG analyses 
+<a class="anchor" aria-label="anchor" href="#r-packages-for-amnog-analyses-"></a>
+</h1>
+<p>Ramnog is a collection of packages for setting up pipelines for AMNOG-style HTA analyses</p>
+<p>The aim of ramnog is that statistician/programmer can set up an AMNOG-type analyses with minimal familiarity with R.</p>
+<p>To get started, check out the <a href="ramnog.html">Quick Start</a> guide</p>
 </div>
 <div class="section level1">
 <h1 id="packages">Packages<a class="anchor" aria-label="anchor" href="#packages"></a>
 </h1>
-<table class="table table table-bordered table table-hover table-condensed table-responsive" style="margin-left: auto; margin-right: auto;">
+<table class="table table table-bordered table table-hover table-condensed table-responsive" style="color: black; margin-left: auto; margin-right: auto;">
 <thead><tr>
-<th style="text-align:left;background-color: lightblue !important;">
+<th style="text-align:left;color: white !important;background-color: rgba(44, 62, 80, 255) !important;">
 Package
 </th>
-<th style="text-align:left;background-color: lightblue !important;">
+<th style="text-align:left;color: white !important;background-color: rgba(44, 62, 80, 255) !important;">
 Description
 </th>
 </tr></thead>
@@ -152,7 +163,8 @@ <h1 id="packages">Packages<a class="anchor" aria-label="anchor" href="#packages"
 <div class="section level1">
 <h1 id="aim">Aim<a class="anchor" aria-label="anchor" href="#aim"></a>
 </h1>
-<p>The aim of {ramnog} is that a programmer has to write minimal code, and no programming to in order to set-up a new AMNOG-type analyses. For each study, the programmer will need to make, adjust, or check the following four types of code:</p>
+<p>The aim of {ramnog} is that a programmer has to write minimal code, and no programming, to set-up a new AMNOG-type analyses.</p>
+<p>For each study, the programmer will need to make, adjust, or check the following four types of code:</p>
 <ol style="list-style-type: decimal">
 <li>The definition of each endpoint (or group of endpoints).</li>
 <li>A set of ADaM functions that makes any modifications to existing ADaM datasets (e.g., new age grouping in ADSL), or makes new ADaM datasets if none exist for the required output.</li>
@@ -164,7 +176,7 @@ <h1 id="aim">Aim<a class="anchor" aria-label="anchor" href="#aim"></a>
 <div class="section level1">
 <h1 id="contributing">Contributing<a class="anchor" aria-label="anchor" href="#contributing"></a>
 </h1>
-<p>We welcome contributions to the code base. Please see the <a href="%22https://hta-pharma.github.io/chefCriteria/dev_git%22" class="external-link">contributing vignette</a> for more information on how to contribute.</p>
+<p>We welcome contributions to the code base. Please see the <a href="dev_contribute.html">contributing vignette</a> for more information on how to contribute.</p>
 </div>
 <div class="section level1">
 <h1 id="installation">Installation<a class="anchor" aria-label="anchor" href="#installation"></a>
@@ -174,7 +186,14 @@ <h1 id="installation">Installation<a class="anchor" aria-label="anchor" href="#i
 <code class="sourceCode R"><span><span class="fu">remotes</span><span class="fu">::</span><span class="fu">install_github</span><span class="op">(</span><span class="st">"hta-pharma/ramnog"</span><span class="op">)</span></span></code></pre></div>
 </div>
 
-  </main><aside class="col-md-3"><div class="license">
+  </main><aside class="col-md-3"><div class="links">
+<h2 data-toc-skip>Links</h2>
+<ul class="list-unstyled">
+<li><a href="https://github.com/hta-pharma/ramnog/" class="external-link">Browse source code</a></li>
+</ul>
+</div>
+
+<div class="license">
 <h2 data-toc-skip>License</h2>
 <ul class="list-unstyled">
 <li><a href="LICENSE.html">Full license</a></li>
@@ -193,10 +212,10 @@ <h2 data-toc-skip>Citation</h2>
 <div class="developers">
 <h2 data-toc-skip>Developers</h2>
 <ul class="list-unstyled">
-<li>MEWP (Matthew David Phelps) <br><small class="roles"> Author </small>  </li>
-<li>NOSJ (Nicolai Skov Johnsen) <br><small class="roles"> Author </small>  </li>
-<li>HSPU (Henrik Sparre Spiegelhauer) <br><small class="roles"> Author </small>  </li>
-<li>CINO (Christian Haargaard Olsen) <br><small class="roles"> Author, maintainer </small>  </li>
+<li>Matthew David Phelps <br><small class="roles"> Author </small>  </li>
+<li>Nicolai Skov Johnsen <br><small class="roles"> Author </small>  </li>
+<li>Henrik Sparre Spiegelhauer <br><small class="roles"> Author </small>  </li>
+<li>Christian Haargaard Olsen <br><small class="roles"> Author, maintainer </small>  </li>
 </ul>
 </div>
 
@@ -208,7 +227,7 @@ <h2 data-toc-skip>Developers</h2>
 
     <footer><div class="pkgdown-footer-left">
   <p></p>
-<p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+<p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/logo.png b/logo.png
index c367ba7c756d02b05fab6a02aa4f00bb4710adfd..d11a5a4c16e76de3d6960683b8923dfe1d4fd2b4 100644
GIT binary patch
delta 90
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delta 90
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diff --git a/pkgdown.yml b/pkgdown.yml
index 8f1a4ad..21bd330 100644
--- a/pkgdown.yml
+++ b/pkgdown.yml
@@ -3,7 +3,8 @@ pkgdown: 2.0.7
 pkgdown_sha: ~
 articles:
   debugging: debugging.html
-  dev_git: dev_git.html
+  dev_contribute: dev_contribute.html
+  dev_devops: dev_devops.html
   ep_overview: ep_overview.html
   ep_spec_adam_data: ep_spec_adam_data.html
   ep_spec_event_def: ep_spec_event_def.html
@@ -14,11 +15,11 @@ articles:
   example_ep_spec: example_ep_spec.html
   methods_criteria: methods_criteria.html
   methods_stat: methods_stat.html
+  qc: qc.html
   ramnog: ramnog.html
   results_datamodel: results_datamodel.html
   results_datamodel2tfl: results_datamodel2tfl.html
-  validation: validation.html
-last_built: 2024-04-08T06:54Z
+last_built: 2024-04-11T06:35Z
 urls:
   reference: https://hta-pharma.github.io/ramnog/reference
   article: https://hta-pharma.github.io/ramnog/articles
diff --git a/reference/dummy_fn.html b/reference/dummy_fn.html
index 97c7f58..e9a7003 100644
--- a/reference/dummy_fn.html
+++ b/reference/dummy_fn.html
@@ -1,16 +1,16 @@
 <!DOCTYPE html>
-<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><meta name="description" content="exists only to import data.table"><title>Title — dummy_fn • ramnog</title><!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="../favicon-16x16.png"><link rel="icon" type="image/png" sizes="32x32" href="../favicon-32x32.png"><link rel="apple-touch-icon" type="image/png" sizes="180x180" href="../apple-touch-icon.png"><link rel="apple-touch-icon" type="image/png" sizes="120x120" href="../apple-touch-icon-120x120.png"><link rel="apple-touch-icon" type="image/png" sizes="76x76" href="../apple-touch-icon-76x76.png"><link rel="apple-touch-icon" type="image/png" sizes="60x60" href="../apple-touch-icon-60x60.png"><script src="../deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet"><script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Title — dummy_fn"><meta property="og:description" content="exists only to import data.table"><meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
+<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><meta name="description" content="exists only to import data.table"><title>Title — dummy_fn • ramnog</title><!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="../favicon-16x16.png"><link rel="icon" type="image/png" sizes="32x32" href="../favicon-32x32.png"><link rel="apple-touch-icon" type="image/png" sizes="180x180" href="../apple-touch-icon.png"><link rel="apple-touch-icon" type="image/png" sizes="120x120" href="../apple-touch-icon-120x120.png"><link rel="apple-touch-icon" type="image/png" sizes="76x76" href="../apple-touch-icon-76x76.png"><link rel="apple-touch-icon" type="image/png" sizes="60x60" href="../apple-touch-icon-60x60.png"><script src="../deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet"><script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet"><meta property="og:title" content="Title — dummy_fn"><meta property="og:description" content="exists only to import data.table"><meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
 <script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script>
 <script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script>
 <![endif]--></head><body>
     <a href="#main" class="visually-hidden-focusable">Skip to contents</a>
     
 
-    <nav class="navbar fixed-top navbar-light navbar-expand-lg bg-light"><div class="container">
+    <nav class="navbar fixed-top navbar-dark navbar-expand-lg bg-primary"><div class="container">
     
     <a class="navbar-brand me-2" href="../index.html">ramnog</a>
 
-    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.1</small>
+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
     <button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@@ -19,48 +19,50 @@
 
     <div id="navbar" class="collapse navbar-collapse ms-3">
       <ul class="navbar-nav me-auto"><li class="nav-item">
-  <a class="nav-link" href="../articles/ramnog.html">Get started</a>
-</li>
-<li class="active nav-item">
-  <a class="nav-link" href="../reference/index.html">Reference</a>
+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
 <li class="nav-item dropdown">
   <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-articles">Articles</a>
   <div class="dropdown-menu" aria-labelledby="dropdown-articles">
     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
-    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint Specification</a>
+    <a class="dropdown-item" href="../articles/ep_overview.html">Endpoint specification overview</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
     <a class="dropdown-item" href="../articles/ep_spec_population_def.html">Analysis Population</a>
     <a class="dropdown-item" href="../articles/ep_spec_event_def.html">Endpoint Events</a>
     <a class="dropdown-item" href="../articles/ep_spec_strata_def.html">Strata</a>
-    <a class="dropdown-item" href="../articles/ep_spec_label.html">Endpoint Label</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Endpoint Statistics</h6>
     <a class="dropdown-item" href="../articles/methods_criteria.html">Criteria Methods</a>
     <a class="dropdown-item" href="../articles/methods_stat.html">Statistical Methods</a>
     <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
-    <a class="dropdown-item" href="../articles/results_datamodel.html">Result Data Model</a>
-    <a class="dropdown-item" href="../articles/results_datamodel2tfl.html">Mapping Results to TFLs</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Endpoint Examples</h6>
+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
     <a class="dropdown-item" href="../articles/example_ep_spec.html">Endpoint Catalog</a>
     <div class="dropdown-divider"></div>
     <h6 class="dropdown-header" data-toc-skip>Debugging</h6>
     <a class="dropdown-item" href="../articles/debugging.html">Debugging</a>
-    <div class="dropdown-divider"></div>
-    <h6 class="dropdown-header" data-toc-skip>Development</h6>
-    <a class="dropdown-item" href="../articles/dev_git.html">Contributing</a>
-    <a class="dropdown-item" href="../articles/validation.html">Quality control for ramnog ecosystem</a>
+  </div>
+</li>
+<li class="nav-item dropdown">
+  <a href="#" class="nav-link dropdown-toggle" data-bs-toggle="dropdown" role="button" aria-expanded="false" aria-haspopup="true" id="dropdown-contributing">Contributing</a>
+  <div class="dropdown-menu" aria-labelledby="dropdown-contributing">
+    <a class="dropdown-item" href="../articles/dev_contribute.html">Contributing overview</a>
+    <a class="dropdown-item" href="../articles/dev_devops.html">DevOps</a>
+    <a class="dropdown-item" href="../articles/qc.html">Quality control</a>
   </div>
 </li>
       </ul><form class="form-inline my-2 my-lg-0" role="search">
         <input type="search" class="form-control me-sm-2" aria-label="Toggle navigation" name="search-input" data-search-index="../search.json" id="search-input" placeholder="Search for" autocomplete="off"></form>
 
-      <ul class="navbar-nav"></ul></div>
+      <ul class="navbar-nav"><li class="nav-item">
+  <a class="external-link nav-link" href="https://github.com/hta-pharma/ramnog/" aria-label="github">
+    <span class="fab fa fab fa-github fa-lg"></span>
+     
+  </a>
+</li>
+      </ul></div>
 
     
   </div>
@@ -68,7 +70,7 @@ <h6 class="dropdown-header" data-toc-skip>Development</h6>
 <div class="row">
   <main id="main" class="col-md-9"><div class="page-header">
       <img src="../logo.png" class="logo" alt=""><h1>Title</h1>
-      
+      <small class="dont-index">Source: <a href="https://github.com/hta-pharma/ramnog/blob/HEAD/R/dummy_fn.R" class="external-link"><code>R/dummy_fn.R</code></a></small>
       <div class="d-none name"><code>dummy_fn.Rd</code></div>
     </div>
 
@@ -93,7 +95,7 @@ <h2 id="value">Value<a class="anchor" aria-label="anchor" href="#value"></a></h2
 
 
     <footer><div class="pkgdown-footer-left">
-  <p></p><p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+  <p></p><p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
 </div>
 
 <div class="pkgdown-footer-right">
diff --git a/reference/figures/logo.png b/reference/figures/logo.png
index c367ba7c756d02b05fab6a02aa4f00bb4710adfd..d11a5a4c16e76de3d6960683b8923dfe1d4fd2b4 100644
GIT binary patch
delta 90
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delta 90
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diff --git a/reference/index.html b/reference/index.html
index bf5da50..ba9070e 100644
--- a/reference/index.html
+++ b/reference/index.html
@@ -1,16 +1,16 @@
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-<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><title>Function reference • ramnog</title><!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="../favicon-16x16.png"><link rel="icon" type="image/png" sizes="32x32" href="../favicon-32x32.png"><link rel="apple-touch-icon" type="image/png" sizes="180x180" href="../apple-touch-icon.png"><link rel="apple-touch-icon" type="image/png" sizes="120x120" href="../apple-touch-icon-120x120.png"><link rel="apple-touch-icon" type="image/png" sizes="76x76" href="../apple-touch-icon-76x76.png"><link rel="apple-touch-icon" type="image/png" sizes="60x60" href="../apple-touch-icon-60x60.png"><script src="../deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet"><script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><meta property="og:title" content="Function reference"><meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
+<!-- Generated by pkgdown: do not edit by hand --><html lang="en"><head><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta charset="utf-8"><meta http-equiv="X-UA-Compatible" content="IE=edge"><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><title>Function reference • ramnog</title><!-- favicons --><link rel="icon" type="image/png" sizes="16x16" href="../favicon-16x16.png"><link rel="icon" type="image/png" sizes="32x32" href="../favicon-32x32.png"><link rel="apple-touch-icon" type="image/png" sizes="180x180" href="../apple-touch-icon.png"><link rel="apple-touch-icon" type="image/png" sizes="120x120" href="../apple-touch-icon-120x120.png"><link rel="apple-touch-icon" type="image/png" sizes="76x76" href="../apple-touch-icon-76x76.png"><link rel="apple-touch-icon" type="image/png" sizes="60x60" href="../apple-touch-icon-60x60.png"><script src="../deps/jquery-3.6.0/jquery-3.6.0.min.js"></script><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"><link href="../deps/bootstrap-5.3.1/bootstrap.min.css" rel="stylesheet"><script src="../deps/bootstrap-5.3.1/bootstrap.bundle.min.js"></script><!-- Font Awesome icons --><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/all.min.css" integrity="sha256-mmgLkCYLUQbXn0B1SRqzHar6dCnv9oZFPEC1g1cwlkk=" crossorigin="anonymous"><link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.12.1/css/v4-shims.min.css" integrity="sha256-wZjR52fzng1pJHwx4aV2AO3yyTOXrcDW7jBpJtTwVxw=" crossorigin="anonymous"><!-- bootstrap-toc --><script src="https://cdn.jsdelivr.net/gh/afeld/bootstrap-toc@v1.0.1/dist/bootstrap-toc.min.js" integrity="sha256-4veVQbu7//Lk5TSmc7YV48MxtMy98e26cf5MrgZYnwo=" crossorigin="anonymous"></script><!-- headroom.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/headroom.min.js" integrity="sha256-AsUX4SJE1+yuDu5+mAVzJbuYNPHj/WroHuZ8Ir/CkE0=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.11.0/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script><!-- clipboard.js --><script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.6/clipboard.min.js" integrity="sha256-inc5kl9MA1hkeYUt+EC3BhlIgyp/2jDIyBLS6k3UxPI=" crossorigin="anonymous"></script><!-- search --><script src="https://cdnjs.cloudflare.com/ajax/libs/fuse.js/6.4.6/fuse.js" integrity="sha512-zv6Ywkjyktsohkbp9bb45V6tEMoWhzFzXis+LrMehmJZZSys19Yxf1dopHx7WzIKxr5tK2dVcYmaCk2uqdjF4A==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/autocomplete.js/0.38.0/autocomplete.jquery.min.js" integrity="sha512-GU9ayf+66Xx2TmpxqJpliWbT5PiGYxpaG8rfnBEk1LL8l1KGkRShhngwdXK1UgqhAzWpZHSiYPc09/NwDQIGyg==" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/mark.min.js" integrity="sha512-5CYOlHXGh6QpOFA/TeTylKLWfB3ftPsde7AnmhuitiTX4K5SqCLBeKro6sPS8ilsz1Q4NRx3v8Ko2IBiszzdww==" crossorigin="anonymous"></script><!-- pkgdown --><script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet"><meta property="og:title" content="Function reference"><meta property="og:image" content="https://hta-pharma.github.io/ramnog/logo.png"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
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+    <small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">0.1.2</small>
 
     
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@@ -19,48 +19,50 @@
 
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+  <a class="nav-link" href="../articles/ramnog.html">Quick start</a>
 </li>
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     <h6 class="dropdown-header" data-toc-skip>Overview</h6>
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-    <h6 class="dropdown-header" data-toc-skip>Endpoint Population and Outcome Specification</h6>
-    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM Data</a>
+    <h6 class="dropdown-header" data-toc-skip>Endpoint population and outcome specification</h6>
+    <a class="dropdown-item" href="../articles/ep_spec_adam_data.html">ADaM specification</a>
     <a class="dropdown-item" href="../articles/ep_spec_treatment_arms.html">Treatment Arms</a>
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-    <h6 class="dropdown-header" data-toc-skip>Endpoint Results</h6>
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+    <h6 class="dropdown-header" data-toc-skip>Examples</h6>
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-      <ul class="navbar-nav"></ul></div>
+      <ul class="navbar-nav"><li class="nav-item">
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   </div>
@@ -91,7 +93,7 @@ <h2 id="all-functions">All functions<a class="anchor" aria-label="anchor" href="
 
 
     <footer><div class="pkgdown-footer-left">
-  <p></p><p>Developed by MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen).</p>
+  <p></p><p>Developed by Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen.</p>
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diff --git a/search.json b/search.json
index e1c177d..5944825 100644
--- a/search.json
+++ b/search.json
@@ -1 +1 @@
-[{"path":"https://hta-pharma.github.io/ramnog/LICENSE.html","id":null,"dir":"","previous_headings":"","what":"MIT License","title":"MIT License","text":"Copyright (c) 2024 Novo Nordisk /S, Danish company registration . 24256790 Permission hereby granted, free charge, person obtaining copy software associated documentation files (“Software”), deal Software without restriction, including without limitation rights use, copy, modify, merge, publish, distribute, sublicense, /sell copies Software, permit persons Software furnished , subject following conditions: copyright notice permission notice shall included copies substantial portions Software. SOFTWARE PROVIDED “”, WITHOUT WARRANTY KIND, EXPRESS IMPLIED, INCLUDING LIMITED WARRANTIES MERCHANTABILITY, FITNESS PARTICULAR PURPOSE NONINFRINGEMENT. EVENT SHALL AUTHORS COPYRIGHT HOLDERS LIABLE CLAIM, DAMAGES LIABILITY, WHETHER ACTION CONTRACT, TORT OTHERWISE, ARISING , CONNECTION SOFTWARE USE DEALINGS SOFTWARE.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"context---why-debugging-is-different","dir":"Articles","previous_headings":"","what":"Context - why debugging is different","title":"Debugging","text":"{chef} pipeline, execution environment managed {targets}, take place working environment. side-effect, straightforward reproduce errors trace back source. Specifically: target {targets} pipeline run new R session closes upon completion hitting error. means working environment clean every run, beneficial reproducibility can make harder debug state led error might readily accessible. {targets} uses caching mechanism avoid re-running successful tasks. feature enhances efficiency, can make debugging tricky. Understanding whether bug due current code cached results might straightforward Sometimes, error messages {targets} pipeline can cryptic informative, making harder figure ’s going wrong. Debugging often requires interactively running code inspect objects states. However, {targets} designed non-interactive batch (sometimes parallel) execution, can make interactive debugging less straightforward. example, just insert browser() function errored like interactive debugging.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"chef-style-debugging","dir":"Articles","previous_headings":"","what":"{chef} style debugging","title":"Debugging","text":"common errors due errors stemming improper user inputs (e.g. user-supplied functions generate input ADaM datasets, contain statistical methods). debug , easiest programmer access state program time errored-. Errors stemming user function split two types: Firstly, relating function formals specifically whether function inputs match supplied {chef}. Secondly, errors arise evaluation function validation output. errors can come bug functions causing crashing runtime, functions return invalid output.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"input-errors","dir":"Articles","previous_headings":"{chef} style debugging","what":"Input errors","title":"Debugging","text":"Input errors stems mismatch expected arguments function arguments {chef} supplies. Errors domain stem improperly defined statistical functions instance statistical functions applied wrong statistical types endpoint specification. function user can define {chef} supplies predefined set arguments (data, statistics, criteria). arguments always supplied, function must either exhaustive function definition, recommended include dots (…) function definition allow functions ignore arguments, required specific function.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"examples","dir":"Articles","previous_headings":"{chef} style debugging > Input errors","what":"Examples:","title":"Debugging","text":"-defined function function require arguments supplied. example, expect---supplied argument specific_arg clearly described well arguments {chef} supplies (study_metadata) full function argument specification. -defined function function explicitly require supplied arguments also doesn’t dots (…) included catch surplus arguments. -defined example function expect supplied study_metadata argument. example also shows optional arguments (default values) displayed.","code":"# Given a data_prepare function: my_data <- function(study_metadata, specific_arg){   #... }  # Would give rise to the following error:  Function (my_data) of type (data_prepare) expects argument(s) which is not supplied:     specific_arg Supplied arguments:     study_metadata Expected arguments: (required, [optional])     specific_arg, study_metadata [] # Given a data_prepare function: my_data <- function(arg_w_default=2){   #... }  # Would give rise to the following error:  Function (my_data) of type (data_prepare) is supplied arguments it does not expect:     study_metadata Supplied arguments:     study_metadata Expected arguments: (required, [optional])      [my_def_arg] Either state all supplied args explicitely or use dots (...) as a passthrough (recommended)."},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"evaluation-and-validation-errors","dir":"Articles","previous_headings":"{chef} style debugging","what":"Evaluation and validation errors","title":"Debugging","text":"{chef} built-helpers provide user state pipeline user-supplied function errors-. using helpers, programmer can access workspace (.e., objects functions) point error. can debug interactively like normal R debugging. broad terms {chef} supply user function input parameters lead erroneous evaluation. {chef} supply debugging sessions function crashes function output compliant. (Statistical output, Criterion output) failures evaluation error message contain keyword EVALUATE non-conforming outputs result errors VALIDATE keyword. Sample error messages can seen following.","code":"# Error message wrt. validation  Error during evaluation of: log(1) Failed to VALIDATE function output with error: Expected (data.table::data.table) Found: numeric  # Error message wrt. evaluation  Error during evaluation of: P-interaction Failed to EVALUATE function with error:  Error : argument \"cell_index\" is missing, with no default"},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"debugging-session","dir":"Articles","previous_headings":"{chef} style debugging > Evaluation and validation errors","what":"Debugging session:","title":"Debugging","text":"evaluation fails output non-compliant {chef} collect inputs function function write file new environment object. debugging environment written debugging subfolder current working directory .RDS file. problem can investigated using built-function chef::load_debug_session() loading directly session using readRDS().","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"debugging-example","dir":"Articles","previous_headings":"{chef} style debugging > Evaluation and validation errors","what":"Debugging example:","title":"Debugging","text":"example review debugging flow faulty stat method. define endpoint single statistic. setup pipeline described End--End examples. execute pipeline tar_make() can check output messages target run: ▶ indicates starting target evaluation ●, ✖ indicates successful failed evaluation respectably. Console output can see pipeline failed evaluation target-step ep_stat_by_strata_by_trt. Furthermore, can view Last error get meaningful error message. shows failed evaluate function aliased n_sub error message Calculation impossible can inspect problem running suggested command: - chef::load_debug_session('/tmp/RtmpCiXPPf/testproj275bcd76287e8d/debug/n_sub.Rdata')  can play around function, given supplied inputs. toy example simply function throws error - simple error fix. However, tool provides possiblity explore tinker functions context fail pipeline. NB. mentioned console message - remember update changes source code!","code":"mk_ep_def <- function() {               ep  <- chef::mk_endpoint_str(                 ..., # The rest of the input parameters.                 stat_by_strata_by_trt = list(\"n_sub\" = n_sub),               )             } tar_make() Loading required package: targets ▶ start target ep ● built target ep [0.038 seconds] ▶ start target ep_id ● built target ep_id [0.001 seconds] (...) # We ignore some other upstream target evaluations. ▶ start target ep_stat_by_strata_by_trt ✖ error target ep_stat_by_strata_by_trt ▶ end pipeline [3.556 seconds] Error: Error running targets::tar_make()   Error messages: targets::tar_meta(fields = error, complete_only = TRUE)   Debugging guide: https://books.ropensci.org/targets/debugging.html   How to ask for help: https://books.ropensci.org/targets/help.html   Last error:  Error during evaluation of: n_sub Failed to EVALUATE function with error:  Error in fn_callable[[1]](dat = dat[[1]], treatment_var = treatment_var,  :    Calculation impossible!  --- Debugging session created: Launch with:  chef::load_debug_session('/tmp/RtmpCiXPPf/testproj275bcd76287e8d/debug/n_sub.Rdata') ---"},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"targets-style-debugging","dir":"Articles","previous_headings":"","what":"Targets style debugging","title":"Debugging","text":"several approaches debugging pipeline erroring . Find much details targets manual: clean R session, load inputs target producing error via tar_load(names = c(<target_names)) debug function target interactively like debug R function Run tar_make(callr_function = NULL) instead usual tar_make. executes pipeline current R session rather seperate R process, can debug interactively using standard R debugging approaches.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_git.html","id":"definition-of-done","dir":"Articles","previous_headings":"","what":"Definition of done","title":"Contributing","text":"feature branch defined done ready PR (pull request) main branch properly tested. Testing consists : Unit-tests test basic functionality Integration testing ensure features work together Passing CI/CD Unit-testing ingegration testing done using testthat framework. New features usually, always require new tests. developing, example new statistical function {chefStats} must checked unit tests. Additionally, previous unit-tests integration tests need pass. can check running devtools::test() respective packages. Note: Integration testing mostly resides {ramnog}, need run devtools::test() well.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_overview.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Endpoint Specification","text":"endpoint specifications comprise central input {chef} contains instructions produce statistics endpoints. specifications contain instructions data use endpoint, statistics include, statistics calculated, group population, criteria must met include endpoint final dossier. specifications must organized data table row contains endpoint specification rows processed independently may represent one endpoints. One single specification may contain instructions produce multiple endpoints e.g. different severity levels system organ classes. result processing endpoint specifications {chef} set statistics, structured long-formatted data table can processed downstream modules e.g. format raw results endpoint tables. scope {chef}. Many components endpoint specifications consist references custom functions outside {chef}, provide high flexibility defining endpoints. endpoint specifications associated custom functions must supplied user inputs {chef} part package. endpoint definition created calling function mk_endpoint_str. endpoint parameters required others optional. Optional parameters default set empty calling mk_endpoint_str, user type endpoint parameters every time required relevant endpoint specification. summary, endpoint specifications can considered cooking recipe along set ingredients (trial data) cooking tools (custom functions) handed chef, {chef}, prepares endpoints. details internal steps {chef} see Getting Started Pipelines.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_adam_data.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"ADaM Data","text":"endpoint needs generated single analysis data set containing information one ADaM data sets. analysis data set created custom ADaM function written trial programmer referenced endpoint specification via data_prepare parameter. ADaM function contains instructions ADaM data sets join, join, custom variables e.g., new groupings, create (). three requirements ADaM function: must exactly one input argument study_metadata endpoint specification parameter, preferably 1-element list, contains relevant information study may used read ADaM data sets. information needed, leave study_metadata unused function set empty list() endpoint specification. must return data.table object. work data.table, can converting tibble data.frame object data.table object end function via data.table::.data.table(my_data_frame). returned table must contain ADAM variables (derived variables) mentioned endpoint specification also subject ID variable USUBJID. summary, analysis data set generation controlled following two parameters endpoint specification: data_prepare: Reference custom function returns single consolidated analysis table contains ADaM data needed endpoint. study_metadata: Object containing study specifics relevant reading ADAM data. Must parsed input ADaM ADSL functions. May empty needed.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_adam_data.html","id":"ex-1-1","dir":"Articles","previous_headings":"","what":"ADaM Data","title":"ADaM Data","text":"example ADAM function first reads ADSL data table {pharmaverseadam}, filters two treatment arms, enriches derived variable. merges enriched ADSL ADAE {pharmaverseadam} return single table ADaM information ADSL ADAE:","code":"# Example of ADaM function that merges information from ADSL and ADAE mk_adam_ex1_1 <- function(study_metadata) {    # Read ADSL from {pharmaverseadam}    adsl <- data.table::as.data.table(pharmaverseadam::adsl)      # Filter treatment arms   adsl <- adsl[adsl$TRT01A %in% c('Placebo', 'Xanomeline High Dose')]      # New derived ADSL variable    adsl[, AGEGR2 := data.table::fcase(AGE < 70, \"AGE < 70\",                                      AGE >= 70, \"AGE >= 70\")]      # Read ADAE from {pharmaverseadam}   adae <- data.table::as.data.table(pharmaverseadam::adae)      # Merge ADSL and ADAE   adae_out <-     merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"), with =                        F], by = \"USUBJID\", all = TRUE)   return(adae_out) }"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_adam_data.html","id":"ex-1-2","dir":"Articles","previous_headings":"","what":"ADaM Data","title":"ADaM Data","text":"might also cases information several ADAM tables required endpoint. example returns ADaM information example addition baseline body weight extracted ADVS. information three ADaM tables merged returned single analysis data set:","code":"# Example of ADaM function that merges information from three ADaM tables mk_adam_ex1_2 <- function(study_metadata) {      # Read ADSL from {pharmaverseadam}    adsl <- data.table::as.data.table(pharmaverseadam::adsl)      # Filter treatment arms   adsl <- adsl[adsl$TRT01A %in% c('Placebo', 'Xanomeline High Dose')]      # New derived ADSL variable    adsl[, AGEGR2 := data.table::fcase(AGE < 70, \"AGE < 70\",                                      AGE >= 70, \"AGE >= 70\")]      # Read ADAE from {pharmaverseadam}   adae <- data.table::as.data.table(pharmaverseadam::adae)    # Read ADVS from {pharmaverseadam}   advs <- data.table::as.data.table(pharmaverseadam::advs)      # Identify baseline body weight   advs_bw <- advs[advs$PARAMCD == \"WEIGHT\" & advs$VISIT == \"BASELINE\"]      # Create new variable bw_baseline   advs_bw[[\"bw_baseline\"]] <- advs_bw[[\"AVAL\"]]      # Merge ADSL, ADAE and baseline body weight from ADVS   ax_out <-     merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"), with = F],            by = \"USUBJID\", all.x = TRUE) |>      merge(x=_, advs_bw[, c(\"bw_baseline\", \"USUBJID\")], by = \"USUBJID\", all.x = TRUE)      return(ax_out) }"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_adam_data.html","id":"ex-1-3","dir":"Articles","previous_headings":"Examples","what":"Ex 1.3","title":"ADaM Data","text":"ADaM functions, defined, need linked corresponding endpoint specifications via data_prepare parameter. creation endpoint specification facilitated mk_endpoint_str function wherein data_prepare parameter established. following example, mk_adam_ex1_2 function utilized produce analysis data intended endpoint.","code":"# Example of endpoint specification of ADaM function. # The dots must be replaced with other required parameters. ep_spec_ex1_3  <- chef::mk_endpoint_str(   data_prepare = mk_adam_ex1_2,   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Endpoint Events","text":"Events records analysis data defined ‘positives’ context endpoint. example, adverse events certain type may events one endpoint, demographic endpoint subjects analysis data (comply period filter) events. Since events bounded rows analysis data, entity event fixed. depends analysis data. may e.g. set visits, measurements, subjects. endpoint definition event controlled via following endpoint specification parameters: period_var: Name flag variable analysis data set indicates record contained required time slot event. period_value: value period_var indicates record required time slot. endpoint_filter: optional parameter contains free text endpoint filter adds period filter defined period_var period_value. group_by: optional parameter splits analysis data exclusive groups injected endpoint. adds narrowing endpoint events disregards events outside group specific endpoint. Let us investigate parameters affect set events exposed endpoint. Initially, input data returned data_prepare filtered create analysis data using population filter c.f. Analysis population. Next, endpoint events analysis data identified according filters . Within endpoint , cell statistics also slices analysis data e.g. strata treatment arm combinations. strata work independently event definition, within strata may event non-events. See Strata details. illustrations depict four possible cases combining event specification parameters.    Case : period filter (period_value period_var) applied case analysis data records meet period filter events. Case B: period filter endpoint filter active. Case C: setup case addition endpoint grouping events restricted within group element. case illustrates setup one group levels (group 1). Case D: setup case B addition endpoint grouping events restricted within group element. case illustrates setup one group levels (group 1).","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html","id":"ex-4-1","dir":"Articles","previous_headings":"","what":"Endpoint Events","title":"Endpoint Events","text":"three examples syntax supplying period filter, endpoint filter endpoint grouping, respectively, endpoint specification.","code":"# Example of partial endpoint specification with period filter ep_spec_ex4_1_1  <- chef::mk_endpoint_str(   period_var = \"ANL01FL\"   period_value = \"Y\",   ...)  # Example of partial endpoint specification with endpoint filtering ep_spec_ex4_1_2  <- chef::mk_endpoint_str(   endpoint_filter = 'ASEV == \"MILD\"',   ...)  # Example of partial endpoint specification with endpoint grouping ep_spec_ex4_1_3  <- chef::mk_endpoint_str(   group_by = list(list(AESEV = c(\"MILD\", \"MODERATE\", \"SERVERE\"))),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html","id":"ex-4-2","dir":"Articles","previous_headings":"","what":"Endpoint Events","title":"Endpoint Events","text":"may also state group levels lazy manner case group levels analysis data set applied. useful group variable many levels e.g., system organ class (SOC), leave certain group levels. example supply lazy grouping SOC.","code":"# Example of partial endpoint specification with lazy endpoint grouping ep_spec_ex4_2  <- chef::mk_endpoint_str(   group_by = list(list(AESOC = c())),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html","id":"ex-4-3","dir":"Articles","previous_headings":"","what":"Endpoint Events","title":"Endpoint Events","text":"case want combine groups multiple variables can state dimension grouping group_by parameter. useful e.g., generating endpoint combination adverse event severity SOC exemplified lazy grouping:","code":"# Example of partial endpoint specification with lazy endpoint grouping on multiple variables ep_spec_ex4_3  <- chef::mk_endpoint_str(   group_by = list(list(AESEV = c(), AESOC = c())),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html","id":"ex-4-4","dir":"Articles","previous_headings":"","what":"Endpoint Events","title":"Endpoint Events","text":"continuation previews example, interested mild adverse events can replace grouping AESEV endpoint filter filters AESEV.","code":"# Example of partial endpoint specification with endpoint filter and lazy grouping ep_spec_ex4_4  <- chef::mk_endpoint_str(   endpoint_filter = 'ASEV == \"MILD\"',   group_by = list(list(AESOC = c())),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_label.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Endpoint Label","text":"endpoint user option specify label describes content endpoint. parsed string via endpoint_label parameter endpoint specification. string may contain references parameters endpoint specification encapsulated <>. references dynamically evaluated respective values parameters. endpoint label unique endpoint, references optional. Label referencing particularly useful endpoint grouping applied, resolves endpoint group level. case may dynamically refer group level present endpoints. dynamic labeling may also convenient way refer important parameters identifies endpoint e.g., pop_var, period_var endpoint_filter.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_label.html","id":"ex-6-1","dir":"Articles","previous_headings":"","what":"Endpoint Label","title":"Endpoint Label","text":"Suppose define endpoint specification endpoint safety analysis population (SAFFL = \"Y\") grouped adverse event severity AESEV three levels: MILD, MODERATE, SERVERE. Note assumes SAFFL AESEV variables analysis data set. setup may specify dynamic endpoint label refer population severity: resolve three endpoints following labels:","code":"# Example of partial endpoint specification of analysis population ep_spec_ex6_1  <- chef::mk_endpoint_str(   pop_var = \"SAFFL\",   pop_value = \"Y\",   group_by = list(list(AESEV = c())),   endpoint_label = \"Example: <pop_var> - <AESEV> adverse events\",   ...) \"Example: SAFFL - MILD adverse events\" \"Example: SAFFL - MODERATE adverse events\" \"Example: SAFFL - SERVERE adverse events\""},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_label.html","id":"ex-6-2","dir":"Articles","previous_headings":"","what":"Endpoint Label","title":"Endpoint Label","text":"extension previous example, suppose want consider subjects ages 18-64 years via age group variable AGEGR1 analysis data set. addition, want update endpoint label refer filter. look like : , resolve three endpoints now endpoint labels:","code":"# Example of partial endpoint specification of analysis population ep_spec_ex6_2  <- chef::mk_endpoint_str(   pop_var = \"SAFFL\",   pop_value = \"Y\",   endpoint_filter = \"AGEGR1 == '18-64'\",   group_by = list(list(AESEV = c())),   endpoint_label =     \"Example: <pop_var> - <AESEV> adverse events / <endpoint_filter>\",   ...) \"Example: SAFFL - MILD adverse events / AGEGR1 == '18-64'\" \"Example: SAFFL - MODERATE adverse events / AGEGR1 == '18-64'\" \"Example: SAFFL - SERVERE adverse events / AGEGR1 == '18-64'\""},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_label.html","id":"ex-6-3","dir":"Articles","previous_headings":"","what":"Endpoint Label","title":"Endpoint Label","text":"provide references endpoint label, simply returned static string. Hence, modify label previous example follows: get following endpoint labels:","code":"# Example of partial endpoint specification of analysis population ep_spec_ex6_3  <- chef::mk_endpoint_str(   pop_var = \"SAFFL\",   pop_value = \"Y\",   endpoint_filter = \"AGEGR1 == '18-64'\",   group_by = list(list(AESEV = c())),   endpoint_label = \"Example of a fixed endpoint label\",   ...) \"Example of a fixed endpoint label\" \"Example of a fixed endpoint label\" \"Example of a fixed endpoint label\""},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_population_def.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Analysis Population","text":"analysis data constitutes records input data set relevant statistics endpoint. can controlled via following endpoint specification parameters filters analysis data analysis population: pop_var: Name flag variable input data set indicates record eligible analysis endpoint. pop_value: value pop_var indicates record eligible. custom_pop_filter: optional parameter contains free text population filter adds filter formed pop_var pop_value. Recommended ad-hoc testing different sub populations. approach records irrelevant endpoint removed early stage, relevant analysis population exposed statistical functions criteria functions.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_population_def.html","id":"ex-3-1","dir":"Articles","previous_headings":"","what":"Analysis Population","title":"Analysis Population","text":"example specification analysis data using safety population flag (assumed present input data returned data_prepare:","code":"# Example of partial endpoint specification of population filter ep_spec_ex3_1  <- chef::mk_endpoint_str(   pop_var = \"SAFFL\",   pop_value = \"Y\",   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_population_def.html","id":"ex-3-2","dir":"Articles","previous_headings":"","what":"Analysis Population","title":"Analysis Population","text":"population may filtered adding custom filter. example, addition population filter example may add custom filter subjects aged least 55 years inlcuded population.","code":"# Example of partial endpoint specification of analysis population ep_spec_ex3_2  <- chef::mk_endpoint_str(   pop_var = \"SAFFL\",   pop_value = \"Y\",   custom_pop_filter = \"AGE >= 55\",   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_strata_def.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Strata","text":"stratify_by endpoint parameter specifies variables analysis data set population sliced endpoint granular comparison treatment arm effects. key properties stratify_by parameter: stratify_by list() object list may empty stratification needed. Regardless whether srtata specified (meet strata criteria c.f. Criteria methods) , endpoint statistics always derived total analysis population endpoint. total can considered special stratum one level. stratum values required stratify_by. relevant statistics applied stratum. strata variables applied independently, .e. strata combined. e.g. stratify age group gender, cross combination SEX=\"F\" & AGEGR=\"<65\". cross combinations two stratum variables B required, either: Create derived variable data_prepare combines B stratify new variable. Use endpoint_filter group_by group filter data stratify B within group level.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_strata_def.html","id":"ex-5-1","dir":"Articles","previous_headings":"","what":"Strata","title":"Strata","text":"","code":"# Example of partial endpoint specification with a strata definition ep_spec_ex5_2  <- chef::mk_endpoint_str(   stratify_by = list(c(\"SEX\")),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_strata_def.html","id":"ex-5-2","dir":"Articles","previous_headings":"","what":"Strata","title":"Strata","text":"Two strata set:","code":"# Example of partial endpoint specification with a strata definition ep_spec_ex5_2  <- chef::mk_endpoint_str(   stratify_by = list(c(\"SEX\", \"AGEGGR1\")),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_strata_def.html","id":"ex-5-3","dir":"Articles","previous_headings":"","what":"Strata","title":"Strata","text":"strata, case total present endpoint:","code":"# Example of partial endpoint specification with a strata definition ep_spec_ex5_3  <- chef::mk_endpoint_str(   stratify_by = list(),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_treatment_arms.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Treatment Arms","text":"treatment arm specifications used split analysis data separate treatment arm assessed compared endpoint. endpoint specification following two parameters must set: treatment_var: Name variable analysis data set contains treatment arms. treatment_refval: value treatment_var corresponds reference/intervention. may used asymmetric statistics compare treatment effects.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_treatment_arms.html","id":"ex-2-1","dir":"Articles","previous_headings":"","what":"Treatment Arms","title":"Treatment Arms","text":"example partial endpoint specification treatment arm specifications:","code":"# Example of endpoint specification of treatment arms. ep_spec_ex2_1  <- chef::mk_endpoint_str(   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"endpoint-types","dir":"Articles","previous_headings":"","what":"Endpoint types","title":"Endpoint Catalog","text":"Binary type 1 Binary type 2 Demographics Continuous outcomes  endpoints , note endpoint specification must contain statistics strata treatment arm (N, n, %), strata across treatment arms (RR, , P-value) across strata treatment arms (P-value interaction) must calculated two strata (Age, Sex). statistical functions come library statistical functions {chefStats}. assume endpoint concerns adverse events must applied full safety population set (SAFFL=\"Y\"). also need functions produce clinical data pass data_prepare. Since examlple analyses adverse events, need version ADAE dataset. exact nature clinical dataset differ project--project, library data prep functions can source . Instead define example functions : Let us consider different variations endpoint specification cases . examples demonstrate apply statistics either full population, grouping system organ class (SOCs) severity, filtered severity. Note set SOCs trimmed according endpoint criterion function (ep_crit_min_subev_by_trt), SOCs least 5 subjects events least one treatment arm included. criteria function come library criteria functions found {chefCriteria}.  get results match table , can group endpoints AESOC, within AESOC grouping, stratify AEDECOD. framing , can see need statistic (n number subjects event E number events) every combination endpoint group (AESOC) stratification level (AEDECOD). statistical functions come chefStats. assume endpoint concerns adverse events must applied full safety population set (SAFFL=\"Y\"). also need functions produce clinical data pass data_prepare. Since examlple analyses adverse events, need version ADAE dataset. exact nature clinical dataset differ project--project, library data prep functions can source . Instead define example functions :  table contains continuous variables (Age, Body Weight Baseline) categorical variables (Age Group, Sex) different statistics applied. endpoint split two endpoint specifications, one continuous variables (case 5), one categorical variables (case 6). categorical variables (Age Group Sex), see need statistic stratification level category (e.g. AGEGR1 < 65 AGEGR1 >= 65). clear get results need, need one statistic per stratification level treatment level. Thus supply statistical function stat_by_strata_by_trt argument endpoint specification. continuous variables less obvious. However, consider TOTAL stratification just like age sex, albeit single level, can see also need one statistic per strata level treatment level, use stat_by_strata_by_trt cases single statistical function applied, (chefStats::demographics_continuous() chefStats::demographics_categorical() respectively) compactly supplies required statistics one function call. Alternatively, can define separate functions statistics apply individually endpoint specification. also need functions produce clinical data pass data_prepare. Since example analyzes body weight, need version ADVS dataset. exact nature clinical dataset differ project--project, library data prep functions can source . Instead define example matches needs analysis: show define demographic endpoints continuous variables categorical variables  table contains statistics baseline characteristics, well change--baseline. observe mean SD calculated combination treatment arm, strata (total age), time (baseline, week 8 16). defining time (AVISIT) endpoint grouping can obtain statistics one endpoint specification. implies : mean SD calculated treatment strata levels (stat_by_strata_by_trt) analysis data columns containing baseline (VALUE_BASELINE) change baseline column (VALUE_CHANGE). Number subjects (N) also calculated treatment strata level (stat_by_strata_by_trt). endpoint grouping (AVISIT) Hedge’s G calculated strata level across treatment arms (stat_by_strata_across_trt). also need functions produce clinical data pass data_prepare. Since example analyses laboratory data, need version ADLB dataset. exact nature clinical dataset differ project--project, library data prep functions can source . Instead define example matches needs analysis: endpoint specification showing summary statistics baseline change baseline shown ","code":"# Merge ADSL and ADAE from {pharmaverseadam} mk_adae <- function(study_metadata) {    # Read ADSL   adsl <- data.table::as.data.table(pharmaverseadam::adsl)    # Filter treatment arms   adsl <- adsl[adsl$TRT01A %in% c(\"Placebo\", \"Xanomeline High Dose\")]    # New derived ADSL age group variable   adsl[, AGEGR2 := data.table::fcase(AGE < 65, \"AGE < 65\",     AGE >= 65, \"AGE >= 65\",     default = NA   )]    # Read ADAE   adae <- data.table::as.data.table(pharmaverseadam::adae)    # Merge ADSL and ADAE   adam_out <-     merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"),       with =         F     ], by = \"USUBJID\", all = TRUE)    return(adam_out) } # Merge ADSL and ADAE from {pharmaverseadam} mk_adae <- function(study_metadata) {    # Read ADSL   adsl <- data.table::as.data.table(pharmaverseadam::adsl)    # Filter treatment arms   adsl <- adsl[adsl$TRT01A %in% c(\"Placebo\", \"Xanomeline High Dose\")]    # New derived ADSL age group variable   adsl[, AGEGR2 := data.table::fcase(AGE < 65, \"AGE < 65\",     AGE >= 65, \"AGE >= 65\",     default = NA   )]    # Read ADAE   adae <- data.table::as.data.table(pharmaverseadam::adae)    # Merge ADSL and ADAE   adam_out <-     merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"),       with =         F     ], by = \"USUBJID\", all = TRUE)    return(adam_out) } ep_spec <- chef::mk_endpoint_str(     data_prepare = mk_adae,     pop_var = \"SAFFL\",     pop_value = \"Y\",     treatment_var = \"TRT01A\",     treatment_refval = \"Xanomeline High Dose\",     group_by = list(list(AESOC = c())),     stratify_by = list(c(\"AEDECOD\")),     stat_by_strata_by_trt = list(chefStats::n_subj_event,                                  chefStats::n_event)   ) # Merge ADSL and ADVS from {pharmaverseadam} mk_advs <- function(study_metadata) {    # Read ADSL   adsl <- data.table::as.data.table(pharmaverseadam::adsl)    # Filter treatment arms   adsl <- adsl[adsl$TRT01A %in% c(\"Placebo\", \"Xanomeline High Dose\")]    # New derived ADSL age group variable   adsl[, AGEGR2 := data.table::fcase(AGE < 65, \"AGE < 65\",     AGE >= 65, \"AGE >= 65\",     default = NA   )]   # Read ADVS   advs <- data.table::as.data.table(pharmaverseadam::advs)    # Identify baseline body weight   advs_bw <- advs[advs$PARAMCD == \"WEIGHT\" & advs$VISIT == \"BASELINE\"]    # Create new variable BW_BASELINE   advs_bw[[\"BW_BASELINE\"]] <- advs_bw[[\"AVAL\"]]    # Merge ADSL, ADAE and baseline body weight from ADVS   adam_out <-     merge(adsl, advs_bw[, c(\"BW_BASELINE\", \"USUBJID\")], by = \"USUBJID\", all.x = TRUE)    return(adam_out) } # Merge ADSL and ADLB from {pharmaverseadam} mk_adlb <- function(study_metadata) {   # Read ADSL   adsl <- data.table::as.data.table(pharmaverseadam::adsl)    # Filter treatment arms   adsl <-     adsl[adsl$TRT01A %in% c(\"Placebo\", \"Xanomeline High Dose\")]    # New derived ADSL age group variable   adsl[, AGEGR2 := data.table::fcase(AGE < 65, \"AGE < 65\",     AGE >= 65, \"AGE >= 65\",     default = NA   )]    # Read ADLB   adlb_0 <- data.table::as.data.table(pharmaverseadam::adlb)   adlb_1 <- adlb_0[adlb_0[[\"PARAMCD\"]] == \"SODIUM\" &       adlb_0[[\"AVISIT\"]] %in% c(\"Baseline\", \"Week 8\", \"Week 16\"), ]    adlb2 <-     merge(adlb_1,       adlb_1[adlb_1$AVISIT == \"Baseline\", c(\"USUBJID\", \"AVAL\")],       by = \"USUBJID\", all.x = TRUE     )    adlb2[[\"VALUE_BASELINE\"]] <- adlb2[[\"AVAL.y\"]]   adlb2[[\"VALUE_CHANGE\"]] <- adlb2[[\"AVAL.x\"]] - adlb2[[\"AVAL.y\"]]    # Merge ADSL and ADLB   adam_out <-     merge(adsl, adlb2[, c(       \"USUBJID\",       \"PARAMCD\",       \"AVISIT\",       \"VALUE_BASELINE\",       \"VALUE_CHANGE\",       \"ANL01FL\"     )], by = \"USUBJID\", all.x = TRUE)    return(adam_out) } chef::mk_endpoint_str(   data_prepare = mk_adlb,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_value = \"Y\",   group_by = list(list(AVISIT = c())),   stratify_by = list(c(\"AGEGR2\")),   stat_by_strata_by_trt = list(     \"n_sub\" = chefStats::n_subj,     \"mean: VALUE_BASELINE\" = c(chefStats::mean_value, var = \"VALUE_BASELINE\"),     \"mean: VALUE_CHANGE\" = c(chefStats::mean_value, var = \"VALUE_CHANGE\"),     \"sd: VALUE_BASELINE\" = c(chefStats::sd_value, var = \"VALUE_BASELINE\"),     \"sd: VALUE_CHANGE\" = c(chefStats::sd_value, var = \"VALUE_CHANGE\")   ),   stat_by_strata_across_trt = list(hedgesg),   endpoint_label = \"Baseline and change from baseline on SODIUM - <AVISIT>\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-1-adverse-events-base-form","dir":"Articles","previous_headings":"Endpoint types","what":"Case 1: Adverse events (base form)","title":"Endpoint Catalog","text":"","code":"ep_spec <- chef::mk_endpoint_str(   data_prepare = mk_adae,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   stratify_by = list(c(\"AGEGR2\", \"SEX\")),   stat_by_strata_by_trt = list(     chefStats::n_subj,     chefStats::n_subj_event,     cheStats::p_subj_event   ),   stat_by_strata_across_trt = list(     chefStats::RR,     chefStats::OR,     chefStats::p_val   ),   stat_across_strata_across_trt = list(chefStats::pval_interaction),   endpoint_label = \"Adverse events - <treatment_var>\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-2-adverse-events-grouped-by-system-organ-class","dir":"Articles","previous_headings":"Endpoint types","what":"Case 2: Adverse events grouped by system organ class","title":"Endpoint Catalog","text":"","code":"ep_spec <- chef::mk_endpoint_str(   data_prepare = mk_adae,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   group_by = list(list(AESOC = c())),   stratify_by = list(c(\"AGEGR2\", \"SEX\")),   stat_by_strata_by_trt = list(     chefStats::n_subj,     chefStats::n_subj_event,     cheStats::p_subj_event   ),   stat_by_strata_across_trt = list(     chefStats::RR,     chefStats::OR,     chefStats::p_val   ),   stat_across_strata_across_trt = list(chefStats::pval_interaction),   crit_endpoint = list(     c(       ep_crit_min_subev_by_trt,       min_n_subev = 5,       requirement_type = \"any\"     )   ),   endpoint_label = \"Adverse events - <AESOC> - <treatment_var>\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-3-mild-adverse-events-grouped-by-system-organ-class","dir":"Articles","previous_headings":"Endpoint types","what":"Case 3: Mild adverse events grouped by system organ class","title":"Endpoint Catalog","text":"","code":"ep_spec <- chef::mk_endpoint_str(   data_prepare = mk_adae,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   endpoint_filter = 'ASEV == \"MILD\"',   group_by = list(list(AESOC = c())),   stratify_by = list(c(\"AGEGR2\", \"SEX\")),   stat_by_strata_by_trt = list(     chefStats::n_subj,     chefStats::n_subj_event,     cheStats::p_subj_event   ),   stat_by_strata_across_trt = list(     chefStats::RR,     chefStats::OR,     chefStats::p_val   ),   stat_across_strata_across_trt = list(chefStats::pval_interaction),   crit_endpoint = list(     c(       ep_crit_min_subev_by_trt,       min_n_subev = 5,       requirement_type = \"any\"     )   ),   endpoint_label = \"Mild adverse events - <treatment_var>\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-4-adverse-events-grouped-by-severity-and-system-organ-class","dir":"Articles","previous_headings":"Endpoint types","what":"Case 4: Adverse events grouped by severity and system organ class","title":"Endpoint Catalog","text":"","code":"ep_spec <- chef::mk_endpoint_str(   data_prepare = mk_adae,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   group_by = list(list(ASEV = c(), AESOC = c())),   stratify_by = list(c(\"AGEGR2\", \"SEX\")),   stat_by_strata_by_trt = list(     chefStats::n_subj,     chefStats::n_subj_event,     cheStats::p_subj_event   ),   stat_by_strata_across_trt = list(     chefStats::RR,     chefStats::OR,     chefStats::p_val   ),   stat_across_strata_across_trt = list(chefStats::pval_interaction),   crit_endpoint = list(     c(       ep_crit_min_subev_by_trt,       min_n_subev = 5,       requirement_type = \"any\"     )   ),   endpoint_label = \"<ASEV> adverse events - <AESOC> - <treatment_var>\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-1-baseline-characteristics-of-analysis-population-continuous-variables","dir":"Articles","previous_headings":"Endpoint types","what":"Case 1: Baseline characteristics of analysis population (continuous variables)","title":"Endpoint Catalog","text":"","code":"chef::mk_endpoint_str(   data_prepare = mk_advs,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   stat_by_strata_by_trt = list(     c(demographics_continuous,       var = \"AGE\"     ),     c(demographics_continuous,       var = \"BW_BASELINE\"     )   ),   endpoint_label = \"Demographics endpoint (categorical measures)\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-2-baseline-characteristics-of-analysis-population-categorical-variables","dir":"Articles","previous_headings":"Endpoint types","what":"Case 2: Baseline characteristics of analysis population (categorical variables)","title":"Endpoint Catalog","text":"collect two endpoint specifications cover complete endpoint:","code":"chef::mk_endpoint_str(   data_prepare = mk_advs,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   stratify_by = list(c(\"AGEGR2\", \"SEX\")),   stat_by_strata_by_trt = list(c(demographics_counts)),   endpoint_label = \"Demographics endpoint (categorical measures)\" ) ep_spec <- rbind(ep_spec_pt1, ep_spec_pt2)"},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"introduction","dir":"Articles","previous_headings":"","what":"Introduction","title":"Criteria Methods","text":"vignette provides short introduction idea analysis criteria. analysis request authorities detail overall set endpoints, irrespective underlying study data. example, might request analysis serious adverse events system organ class, gender. analyses may contain many cells zeros, low counts. ensure analyses contain meaningfully amounts data included, request may additionally include certain criteria inclusion analysis, threshold minimum number records, events, subjects. logic analysis inclusion criteria handled functions supplied crit_endpoint, crit_by_strata_by_trt, crit_by_strata_across_trt arguments defining endpoint mk_endpoints_str().","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"criteria-levels","dir":"Articles","previous_headings":"","what":"Criteria levels","title":"Criteria Methods","text":"Currently, {chef} supports analysis inclusion criteria three parts analysis output, colors corresponding figure : entire endpoint stat_by_strata_by_trt stat_by_strata_across_trt stat_across_strata_across_trt  criteria functions hierarchical; failure meet criteria Level (Entire Endpoint) implies automatic failure Levels B C. Similarly, passing Level failing Level B results failure Level C. endpoint satisfy certain criterion, associated statistical functions execute reduce compute time. instance, endpoint meet criteria Level B, strata across treatment arms analyses performed. However, analyses Totals still proceed. important note criteria optional. every endpoint definition needs incorporate three levels criteria. analyses may criteria, others might require criteria endpoint strata. NOTE crit_by_strata_across_trt criterion gate-keep stat_by_strata_across_trt stat_across_strata_across_trt (stippled box). stat_across_strata_across_trt seen lower hierarchical criteria ladder stat_by_strata_across_trt - however seperate criterion time therefore included default.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"function-formals","dir":"Articles","previous_headings":"","what":"Function formals","title":"Criteria Methods","text":"Chef supplies number parameters criterion functions. parameters vary according statistical method. Note crit_by_strata_by_trt, crit_by_strata_across_trt formals functions identical.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"input-specifications","dir":"Articles","previous_headings":"Function formals","what":"Input specifications","title":"Criteria Methods","text":"criteria functions served broad set parameters. reflects need flexibility criteria functions. flexibility allows set criteria affect specific stratum based specific stratum information shared across multiple strata. allows create criteria functions target one stratum act across whole strata: Criteria1 requires endpoint strata GENDER must balanced. (ie approx 50/50 distribution.) (requires stratify_by parameter) Criteria2 requires endpoint strata (GENDER, AGE) must balanced. (requires stratify_by parameter) may also also design criteria endpoints, includes case enough subjects relevant strata. See Examples NB Similar stat methods require criteria function include ellipses (...) wildcard parameter. convenience, since need explicitly state used parameters function definition. However, importantly ensure criteria function define today also work tomorrow, {chef} may supply parameters criteria functions. Endpoint criteria functions Strata criteria functions","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"output-specifications","dir":"Articles","previous_headings":"Function formals","what":"Output specifications","title":"Criteria Methods","text":"output criteria function must simple boolean (TRUE FALSE)","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"example-functions","dir":"Articles","previous_headings":"Function formals","what":"Example functions","title":"Criteria Methods","text":"two examples showcasing write criteria functions. within scope {chef} package provide library criteria functions. Endpoint criteria functions Strata criteria functions Generic criteria function: Allows control endpoint inclusion based count subjects events arms. function generic can specified mk_endpoint_str curried beforehand (Stat methods-Currying) include across strata treatment arm analysis least X subjects events treatment arm. requirement_type==“” just single cell (stratum + treatment arm) needs included.","code":"ep_criteria.treatment_arms_minimum_unique_event_count <- function(     dat,     event_index,     treatment_var,     subjectid_var,     minimum_event_count,     requirement_type = c(\"any\", \"all\")     ...     )   # rows with events   dat_events <- dat[J(event_index),]    # Bolean of whether the count of unique subjects    # within each treatment arm is above the minimum count.     dat_lvl_above_threshold <- dat_events[     ,      list(\"is_above_minimum\" = data.table::uniqueN(subjectid_var)>=minimum_event_count),      by=treatment_var   ]      if requirement_type == \"any\":     return( any(dat_lvl_above_threshold$V1) )   return( all(dat_lvl_above_threshold$V1) ) ep_strata_criteria.strata_treatment_arm_minimum_unique_count <- function(     dat,     event_index,     treatment_var,     subjectid_var,     strata_var,     minimum_event_count,     requirement_type = c(\"any\", \"all\")     ...     )   # rows with events   dat_events <- dat[J(event_index),]    # Bolean of whether the count of unique subjects    # within each treatment arm is above the minimum count.     dat_lvl_above_threshold <- dat_events[     ,      list(\"is_above_minimum\" = data.table::uniqueN(subjectid_var)>=minimum_event_count),      by=c(treatment_var, strata_var)   ]      if requirement_type == \"any\":     return( any(dat_lvl_above_threshold$is_above_minimum) )   return( all(dat_lvl_above_threshold$is_above_minimum) )"},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"applying-criteria-functions","dir":"Articles","previous_headings":"Function formals","what":"Applying criteria functions","title":"Criteria Methods","text":"Criteria functions supplied mk_endpoint_str function used gatekeep statistical function run. example endpoint : look population event E_XYZ. interested endpoint see least 5 subjects arms event E_XYZ. interested getting descriptive statistic strata (say GENDER, AGEGRP) levels within least 1 subject. Finally, run across treatment arm statistics least 5 subject stratum treatment arm. requirements/gates implemented currying functions given Examples section.","code":"# R/project_criteria.R # Curry the general criteria functions from [Examples](#examples)  crit_accept_endpoint.5_subjects_any_treatment_arm <- purrr:partial(   ep_criteria.treatment_arms_minimum_unique_event_count,   minimum_event_count = 5,   requirement_type = \"any\" )  crit_strata.1_subject_all_treatment_strata <- purrr:partial(   ep_sg_criteria.sg_treatment_arm_minimum_unique_count,   minimum_event_count = 1,   requirement_type = \"all\" )  crit_strata.5_subject_all_treatment_strata <- purrr:partial(   ep_sg_criteria.sg_treatment_arm_minimum_unique_count,   minimum_event_count = 5,   requirement_type = \"all\" )  # R/project_endpoints.R  endpoint_XYZ  <- chef::mk_endpoint_str(   ..., # Setting the rest of the inputs   crit_endpoint = list(crit_accept_endpoint.5_subjects_any_treatment_arm),   crit_by_strata_by_trt = list(crit_strata.1_subject_all_treatment_strata),   crit_by_strata_across_trt = list(crit_strata.5_subject_all_treatment_strata) )"},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_stat.html","id":"statistical-method-types","dir":"Articles","previous_headings":"","what":"Statistical method types","title":"Statistical Methods","text":"{chef} framework categorizes statistical functions three main categories depending operate stratification levels treatment levels. Operations can either done per stratification level treatment level, can operate across levels. Figure 1 shows typical table safety analysis color codes result based function type creates : Figure 1 Table 1 provides description three function types, color coded outputs produce table 1 : Table 1 function type also determines function applied. example figure 1, stat_by_strata_by_trt function called combination stratification level treatment level, well TOTALS treatment level: SEX == “MALE” & TRT == “TreatmentA” SEX == “FEMALE” & TRT == “TreatmentA” SEX == “MALE” & TRT == “TreatmentB” SEX == “FEMALE” & TRT == “TreatmentB” AGE == “<65” & TRT == “TreatmentA” AGE == “>=65” & TRT == “TreatmentA” AGE == “<65” & TRT == “TreatmentB” AGE == “>=65” & TRT == “TreatmentB” TOTAL_ == “total” & TRT == “TreatmentA” TOTAL_ == “total” & TRT == “TreatmentB” Whereas stat_across_strata_across_trt called per stratification “group”, .e.: strata_var == “SEX” strata_var == “AGE”","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_stat.html","id":"project-specific-statistical-functions","dir":"Articles","previous_headings":"","what":"Project-specific statistical functions","title":"Statistical Methods","text":"need statistical function exist {chefStats}, writing adding chefStats package, way can used others - please see documentation chefStats package details. sometimes might make sense. case can always reference custom function endpoint specification stored R/ directory project folder. example want new function my_custom_stats_function type stat_by_strata_by_trt . first define function: ’s save R/, can reference endpoint specification just like chefStats functions: Important: custom function relies external packages, need add packages packages.R file R/.","code":"my_custom_function <- function(     # function arguments here   ){   # Function does something here } chef::mk_endpoint_str(   ..., # other arguments to mk_endpoint_str   stat_by_strata_by_trt = my_custom_function)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"set-up-project-infrastructure","dir":"Articles","previous_headings":"","what":"1. Set up project infrastructure","title":"Quick Start","text":"assumes set RStudio project (equivalent). done , first. setup chef project need: functions used make ADaM data ingested chef pipeline R function produces endpoint specification object analysis/statistical functions sourced R packages (like chefStats chefCriteria) script containing library() calls package needed pipeline run pipeline/ directory targets pipeline(s) /defined targets.yml file tracking different pipelines file file structure look like : {chef} convenience function set infrastructure : sets following file structure: now need know file R/ . _targets.yml pipeline_01.R explanation, see vignette(\"pipeline\").","code":"<R-project dir>/     |-- R/         |--- mk_endpoint_definition.R         |--- mk_adam.R         |--- packages.R     |-- pipeline/         |--- pipeline_01.R     |-- _targets.yaml library(chef)     chef::use_chef(       pipeline_id = \"01\"     )"},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"specify-an-endpoint","dir":"Articles","previous_headings":"","what":"1. Specify an endpoint","title":"Quick Start","text":"Endpoint specifications need created inside function, case function defined mk_endpoint_definition.R endpoint created using chef::mk_endpoint_str() function. explanation specify endpoints, see vignette(\"endpoint_definitions\"). specify minimal working endpoint based adae dataset supplied {pharmaverseadam}. modifying R/mk_endpoint_definition.R file looks like : might notice couple things specification: stratify_by field refer variable called AGEGR2, however ADAE dataset {pharmaverseadam} contain variable. derive variable inside mk_adae (see next section).","code":"mk_endpoint_def <- function() {   chef::mk_endpoint_str(     study_metadata = list(),     pop_var = \"SAFFL\",     pop_value = \"Y\",     treatment_var = \"TRT01A\",     treatment_refval = \"Xanomeline High Dose\",     stratify_by = list(c(\"AGEGR2\")),     data_prepare = mk_adae,     endpoint_label = \"A\",     custom_pop_filter = \"TRT01A %in% c('Placebo', 'Xanomeline High Dose')\",     stat_by_strata_by_trt = list(\"N_subj_event\" = c(chefStats::n_subj_event))   ) }"},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"define-the-input-dataset","dir":"Articles","previous_headings":"","what":"2. Define the input dataset","title":"Quick Start","text":"also need provide chef ADAE input data set corresponds endpoint specified . read make data sets, see vignette(\"mk_adam\"). can see strata based AGEGR2, can derived AGE variable ADSL. now, write simple ADaM function mk_adae merges ADSL data set (enriched AGEGR2) onto ADAE data set, thereby creating input data set.","code":"mk_adae <- function(study_metadata) {   adae <- data.table::as.data.table(pharmaverseadam::adae)   adsl <- data.table::as.data.table(pharmaverseadam::adsl)   adsl[, AGEGR2 := data.table::fcase(AGE < 70, \"AGE < 70\",                                      AGE >= 70, \"AGE >= 70\")]   adae_out <-     merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"), with =                        F], by = \"USUBJID\", all = TRUE)   adae_out[] }"},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"define-the-analysis-methods","dir":"Articles","previous_headings":"","what":"3. Define the analysis methods","title":"Quick Start","text":"Now specified endpoint analyzed, defined analysis data set {chef}, need define analysis . goal analysis count number events experiencing event. need define function makes calculations, give function chef. want result per treatment arm - strata combination, must provide function stat_by_strata_by_trt argument endpoint specification. already argument set chefStats::n_subj_event example endpoint specification ","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"run-the-analysis-pipeline","dir":"Articles","previous_headings":"","what":"4. Run the analysis pipeline","title":"Quick Start","text":"Now inputs defined, can run pipeline. achieved call tar_make() {targets} package. Targets show steps pipeline executed long step took: , see results, load cached step pipeline corresponding results. case ep_stat, load sessions object call Now ep_stat R object like . Thus can look results simply running However, lot extra data included object, lets look column subsection first 5 rows:","code":"targets::tar_make() ## Loading required package: targets ## ▶ dispatched target ep ## ● completed target ep [0.03 seconds] ## ▶ dispatched target ep_id ## ● completed target ep_id [0.009 seconds] ## ▶ dispatched branch ep_fn_map_c85cfecb ## ● completed branch ep_fn_map_c85cfecb [0.032 seconds] ## ● completed pattern ep_fn_map ## ▶ dispatched target user_def_fn ## ● completed target user_def_fn [0.003 seconds] ## ▶ dispatched target study_data ## ● completed target study_data [0.035 seconds] ## ▶ dispatched target fn_map_tibble ## ● completed target fn_map_tibble [0.004 seconds] ## ▶ dispatched branch ep_and_data_c85cfecb ## ● completed branch ep_and_data_c85cfecb [0.01 seconds] ## ● completed pattern ep_and_data ## ▶ dispatched branch fn_map_ddcbeaef ## ● completed branch fn_map_ddcbeaef [0.001 seconds] ## ● completed pattern fn_map ## ▶ dispatched branch analysis_data_container_a4b422b1 ## ● completed branch analysis_data_container_a4b422b1 [0 seconds] ## ● completed pattern analysis_data_container ## ▶ dispatched branch ep_with_data_key_a4b422b1 ## ● completed branch ep_with_data_key_a4b422b1 [0.001 seconds] ## ● completed pattern ep_with_data_key ## ▶ dispatched branch ep_expanded_e741f3f8 ## ● completed branch ep_expanded_e741f3f8 [0.02 seconds] ## ● completed pattern ep_expanded ## ▶ dispatched branch ep_event_index_5f7976c8 ## ● completed branch ep_event_index_5f7976c8 [0.003 seconds] ## ● completed pattern ep_event_index ## ▶ dispatched branch ep_crit_endpoint_ebe3bbc0 ## ● completed branch ep_crit_endpoint_ebe3bbc0 [0.004 seconds] ## ● completed pattern ep_crit_endpoint ## ▶ dispatched branch ep_crit_by_strata_by_trt_d8af90e8 ## ● completed branch ep_crit_by_strata_by_trt_d8af90e8 [0.012 seconds] ## ● completed pattern ep_crit_by_strata_by_trt ## ▶ dispatched branch ep_crit_by_strata_across_trt_843ad8b9 ## ● completed branch ep_crit_by_strata_across_trt_843ad8b9 [0.003 seconds] ## ● completed pattern ep_crit_by_strata_across_trt ## ▶ dispatched branch ep_prep_by_strata_across_trt_eb25bb25 ## ● completed branch ep_prep_by_strata_across_trt_eb25bb25 [0.001 seconds] ## ● completed pattern ep_prep_by_strata_across_trt ## ▶ dispatched branch ep_prep_across_strata_across_trt_eb25bb25 ## ● completed branch ep_prep_across_strata_across_trt_eb25bb25 [0.002 seconds] ## ● completed pattern ep_prep_across_strata_across_trt ## ▶ dispatched branch ep_prep_by_strata_by_trt_eb25bb25 ## ● completed branch ep_prep_by_strata_by_trt_eb25bb25 [0.035 seconds] ## ● completed pattern ep_prep_by_strata_by_trt ## ▶ dispatched target ep_rejected ## ● completed target ep_rejected [0 seconds] ## ▶ dispatched branch ep_stat_by_strata_across_trt_0a80cb2c ## ● completed branch ep_stat_by_strata_across_trt_0a80cb2c [0 seconds] ## ● completed pattern ep_stat_by_strata_across_trt ## ▶ dispatched branch ep_stat_across_strata_across_trt_a619c1df ## ● completed branch ep_stat_across_strata_across_trt_a619c1df [0 seconds] ## ● completed pattern ep_stat_across_strata_across_trt ## ▶ dispatched branch ep_stat_by_strata_by_trt_acada2e0 ## ● completed branch ep_stat_by_strata_by_trt_acada2e0 [0.015 seconds] ## ● completed pattern ep_stat_by_strata_by_trt ## ▶ dispatched target ep_stat_nested ## ● completed target ep_stat_nested [0 seconds] ## ▶ dispatched target ep_stat ## ● completed target ep_stat [0.004 seconds] ## ▶ ended pipeline [0.441 seconds] ## targets::tar_load(ep_stat) ep_stat ep_stat[, .(   treatment_var,   treatment_refval,   strata_var,   stat_filter,   stat_result_label,   stat_result_description,   stat_result_qualifiers,   stat_result_value )] |> head() ##    treatment_var     treatment_refval strata_var ##           <char>               <char>     <char> ## 1:        TRT01A Xanomeline High Dose     TOTAL_ ## 2:        TRT01A Xanomeline High Dose     TOTAL_ ## 3:        TRT01A Xanomeline High Dose     AGEGR2 ## 4:        TRT01A Xanomeline High Dose     AGEGR2 ## 5:        TRT01A Xanomeline High Dose     AGEGR2 ## 6:        TRT01A Xanomeline High Dose     AGEGR2 ##                                                 stat_filter stat_result_label ##                                                      <char>            <char> ## 1:                  TOTAL_ == \"total\" & TRT01A == \"Placebo\"                 n ## 2:     TOTAL_ == \"total\" & TRT01A == \"Xanomeline High Dose\"                 n ## 3:               AGEGR2 == \"AGE < 70\" & TRT01A == \"Placebo\"                 n ## 4:              AGEGR2 == \"AGE >= 70\" & TRT01A == \"Placebo\"                 n ## 5:  AGEGR2 == \"AGE < 70\" & TRT01A == \"Xanomeline High Dose\"                 n ## 6: AGEGR2 == \"AGE >= 70\" & TRT01A == \"Xanomeline High Dose\"                 n ##           stat_result_description stat_result_qualifiers stat_result_value ##                            <char>                 <char>             <num> ## 1: Number of subjects with events                   <NA>                86 ## 2: Number of subjects with events                   <NA>                72 ## 3: Number of subjects with events                   <NA>                22 ## 4: Number of subjects with events                   <NA>                64 ## 5: Number of subjects with events                   <NA>                18 ## 6: Number of subjects with events                   <NA>                54"},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"pass-the-data-on-to-tfl-formatting","dir":"Articles","previous_headings":"","what":"5. Pass the data on to TFL formatting","title":"Quick Start","text":"Now data produced, can pass TFL formatting (outside scope {chef}).","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/validation.html","id":"unit-testing","dir":"Articles","previous_headings":"","what":"Unit testing","title":"Quality control for ramnog ecosystem","text":"package contains unit tests functionality package responsible . means, example, responsibility unit-tests {chefStats} ensure statistical functions written chefStats produce result supposed produce.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/validation.html","id":"integration-testing","dir":"Articles","previous_headings":"","what":"Integration testing","title":"Quality control for ramnog ecosystem","text":"Integration testing verifies framework produces expected results integration testing done via {testthat} framework, essentially unit-tests cover many different units goal compare results analysis run via ramnog expected results done manual calculation analysis. example, unit test ensure results endpoint definition defined run via chef match calculated manually","code":"testthat::test_that(\"Valide stats when one strata level is not found\",           {             # SETUP -------------------------------------------------------------------             testr::create_local_project()             mk_adae <- function(study_metadata) {               adsl <- pharmaverseadam::adsl |> data.table::setDT()               adae <- pharmaverseadam::adae |> data.table::setDT()               adae_out <-                 merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"), with =                                    F], by = \"USUBJID\", all = TRUE)               adae_out[TRT01A %in% c('Placebo', 'Xanomeline High Dose'),]             }             mk_ep_def <- function() {               chef::mk_endpoint_str(                 study_metadata = list(),                 pop_var = \"SAFFL\",                 pop_value = \"Y\",                 treatment_var = \"TRT01A\",                 treatment_refval = \"Xanomeline High Dose\",                 stratify_by = list(c(\"SEX\")),                 data_prepare = mk_adae,                 endpoint_label = \"A\",                 custom_pop_filter = \"SEX == 'F'\",                 group_by = list(list(AESEV = c())),                 stat_by_strata_by_trt = list(                   \"N\" = chefStats::n_subj,                   \"E\" = chefStats::n_event,                   \"N subj E\" = chefStats::n_subj_event                 ),                 stat_by_strata_across_trt = list(\"RR\" = chefStats::RR,                                                  \"OR\" = chefStats::OR),                 stat_across_strata_across_trt = list(\"P-interaction\" = chefStats::p_val_interaction)               )             }              chef::use_chef(               pipeline_dir = \"pipeline\",               r_functions_dir = \"R/\",               pipeline_id = \"01\",               mk_endpoint_def_fn = mk_ep_def,               mk_adam_fn = list(mk_adae)             )             # ACT ---------------------------------------------------------------------             targets::tar_make()             targets::tar_load(ep_stat)             # EXPECT ------------------------------------------------------------------             # Manually calculated expected results             x <- mk_adae(study_metadata = NULL)             # Relative Risk             actual <-               ep_stat[endpoint_group_filter == \"AESEV == \\\"SEVERE\\\"\" &                         fn_name == \"RR\" &                         stat_filter == \"SEX == \\\"F\\\"\" & stat_result_label == \"RR\", stat_result_value]             x1 <- x[SEX == \"F\" & SAFFL == \"Y\"]             x1[, event := FALSE]             x1[AESEV == \"SEVERE\", event := TRUE] |> data.table::setorder(-event)             x1_unique <-               unique(x1, by = \"USUBJID\", fromLast = FALSE)             two_by_two <-               x1_unique[, .N, by = .(TRT01A, event)][order(TRT01A, event)]                          # Outcome, exposed             a <-               two_by_two[TRT01A == \"Xanomeline High Dose\" &                            (event), N]                           # No outcome, exposed             b <-               two_by_two[TRT01A == \"Xanomeline High Dose\" &                            !(event), N]                            # Outcome, not exposed             c <-               two_by_two[TRT01A == \"Placebo\" &                            (event), N]                          # No outcome, not exposed             d <-               two_by_two[TRT01A == \"Placebo\" &                            !(event), N]                           expected <- (a / sum(a, b)) / (c / sum(c, d))             expect_identical(actual, expected)              # Number of Events             actual <-               ep_stat[endpoint_group_filter == \"AESEV == \\\"SEVERE\\\"\" &                         fn_name == \"E\" &                         strata_var == \"SEX\"]             expected <-               x1[(event), .N, by = .(TRT01A)][order(TRT01A)][, as.double(N)]             expect_identical(actual$stat_result_value, expected)           }) #> v Setting active project to '/tmp/RtmpUJWI5T/testproj1d40f9007ce' #> v Writing 'R/packages.R' #> v Writing 'pipeline/pipeline_01.R' #> * Edit 'pipeline/pipeline_01.R' #> * Edit 'R/mk_adae.R' #> i Renaming \"mk_ep_def\" to \"mk_endpoint_def.R\" #>  #> * Edit 'R/mk_endpoint_def.R' #> Loading required package: targets #> ▶ dispatched target ep #> ● completed target ep [0.03 seconds] #> ▶ dispatched target ep_id #> ● completed target ep_id [0.009 seconds] #> ▶ dispatched branch ep_fn_map_a9f94f07 #> ● completed branch ep_fn_map_a9f94f07 [0.034 seconds] #> ● completed pattern ep_fn_map #> ▶ dispatched target user_def_fn #> ● completed target user_def_fn [0.004 seconds] #> ▶ dispatched target study_data #> ● completed target study_data [0.037 seconds] #> ▶ dispatched target fn_map_tibble #> ● completed target fn_map_tibble [0.005 seconds] #> ▶ dispatched branch ep_and_data_a9f94f07 #> ● completed branch ep_and_data_a9f94f07 [0.009 seconds] #> ● completed pattern ep_and_data #> ▶ dispatched branch fn_map_e395012c #> ● completed branch fn_map_e395012c [0 seconds] #> ● completed pattern fn_map #> ▶ dispatched branch analysis_data_container_5d792ea5 #> ● completed branch analysis_data_container_5d792ea5 [0 seconds] #> ● completed pattern analysis_data_container #> ▶ dispatched branch ep_with_data_key_5d792ea5 #> ● completed branch ep_with_data_key_5d792ea5 [0 seconds] #> ● completed pattern ep_with_data_key #> ▶ dispatched branch ep_expanded_0ccac0a6 #> ● completed branch ep_expanded_0ccac0a6 [0.041 seconds] #> ● completed pattern ep_expanded #> ▶ dispatched branch ep_event_index_74b91187 #> ● completed branch ep_event_index_74b91187 [0.006 seconds] #> ● completed pattern ep_event_index #> ▶ dispatched branch ep_crit_endpoint_808724c0 #> ● completed branch ep_crit_endpoint_808724c0 [0.004 seconds] #> ● completed pattern ep_crit_endpoint #> ▶ dispatched branch ep_crit_by_strata_by_trt_11e8f8cc #> ● completed branch ep_crit_by_strata_by_trt_11e8f8cc [0.009 seconds] #> ● completed pattern ep_crit_by_strata_by_trt #> ▶ dispatched branch ep_crit_by_strata_across_trt_499441a5 #> ● completed branch ep_crit_by_strata_across_trt_499441a5 [0.004 seconds] #> ● completed pattern ep_crit_by_strata_across_trt #> ▶ dispatched branch ep_prep_by_strata_across_trt_def62385 #> ● completed branch ep_prep_by_strata_across_trt_def62385 [0.035 seconds] #> ● completed pattern ep_prep_by_strata_across_trt #> ▶ dispatched branch ep_prep_across_strata_across_trt_def62385 #> ● completed branch ep_prep_across_strata_across_trt_def62385 [0.013 seconds] #> ● completed pattern ep_prep_across_strata_across_trt #> ▶ dispatched branch ep_prep_by_strata_by_trt_def62385 #> ● completed branch ep_prep_by_strata_by_trt_def62385 [0.098 seconds] #> ● completed pattern ep_prep_by_strata_by_trt #> ▶ dispatched target ep_rejected #> ● completed target ep_rejected [0.001 seconds] #> ▶ dispatched branch ep_stat_by_strata_across_trt_c10bbb71 #> ● completed branch ep_stat_by_strata_across_trt_c10bbb71 [0.1 seconds] #> ● completed pattern ep_stat_by_strata_across_trt #> ▶ dispatched branch ep_stat_across_strata_across_trt_dbe17584 #> ● completed branch ep_stat_across_strata_across_trt_dbe17584 [0.032 seconds] #> ● completed pattern ep_stat_across_strata_across_trt #> ▶ dispatched branch ep_stat_by_strata_by_trt_c21489be #> ● completed branch ep_stat_by_strata_by_trt_c21489be [0.042 seconds] #> ● completed pattern ep_stat_by_strata_by_trt #> ▶ dispatched target ep_stat_nested #> ● completed target ep_stat_nested [0 seconds] #> ▶ dispatched target ep_stat #> ● completed target ep_stat [0.013 seconds] #> ▶ ended pipeline [0.795 seconds] #> v Restoring original working directory: '/home/runner/work/ramnog/ramnog/vignettes/' #> v Setting active project to '<no active project>' #> v Deleting temporary project: '/tmp/RtmpUJWI5T/testproj1d40f9007ce/' #> Test passed"},{"path":"https://hta-pharma.github.io/ramnog/articles/validation.html","id":"cicd","dir":"Articles","previous_headings":"","what":"CI/CD","title":"Quality control for ramnog ecosystem","text":"added.","code":""},{"path":"https://hta-pharma.github.io/ramnog/authors.html","id":null,"dir":"","previous_headings":"","what":"Authors","title":"Authors and Citation","text":"MEWP (Matthew David Phelps). Author. NOSJ (Nicolai Skov Johnsen). Author. HSPU (Henrik Sparre Spiegelhauer). Author. CINO (Christian Haargaard Olsen). Author, maintainer.","code":""},{"path":"https://hta-pharma.github.io/ramnog/authors.html","id":"citation","dir":"","previous_headings":"","what":"Citation","title":"Authors and Citation","text":"MEWP (Matthew David Phelps), NOSJ (Nicolai Skov Johnsen), HSPU (Henrik Sparre Spiegelhauer), CINO (Christian Haargaard Olsen) (2024). ramnog: Facilitating AMNOG style analysis pipelines. R package version 0.1.1, https://hta-pharma.github.io/ramnog/.","code":"@Manual{,   title = {ramnog: Facilitating AMNOG style analysis pipelines},   author = {{MEWP (Matthew David Phelps)} and {NOSJ (Nicolai Skov Johnsen)} and {HSPU (Henrik Sparre Spiegelhauer)} and {CINO (Christian Haargaard Olsen)}},   year = {2024},   note = {R package version 0.1.1},   url = {https://hta-pharma.github.io/ramnog/}, }"},{"path":"https://hta-pharma.github.io/ramnog/index.html","id":"ramnog-","dir":"","previous_headings":"","what":"Facilitating AMNOG style analysis pipelines","title":"Facilitating AMNOG style analysis pipelines","text":"{ramnog} package collection packages setting pipelines AMNOG-style HTA analyses. aim {ramnog} enable statisticians/programmers set AMNOG-type analyses minimal familiarity R.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/index.html","id":"aim","dir":"","previous_headings":"","what":"Aim","title":"Facilitating AMNOG style analysis pipelines","text":"aim {ramnog} programmer write minimal code, programming order set-new AMNOG-type analyses. study, programmer need make, adjust, check following four types code: definition endpoint (group endpoints). set ADaM functions makes modifications existing ADaM datasets (e.g., new age grouping ADSL), makes new ADaM datasets none exist required output. (needed) Define set criteria endpoint included results. library criteria stored companion package {chefCriteria}. specification statistical functions used summarize/analyze data. library functions provided {chefStats} package. core principal frameworks design modularity. core functionality framework resides {chef} change slowly, functionality subject frequent changes sectioned packages ({chefStats} {chefCriteria}).","code":""},{"path":"https://hta-pharma.github.io/ramnog/index.html","id":"contributing","dir":"","previous_headings":"","what":"Contributing","title":"Facilitating AMNOG style analysis pipelines","text":"welcome contributions code base. Please see contributing vignette information contribute.","code":""},{"path":"https://hta-pharma.github.io/ramnog/index.html","id":"installation","dir":"","previous_headings":"","what":"Installation","title":"Facilitating AMNOG style analysis pipelines","text":"packages available install GitHub:","code":"remotes::install_github(\"hta-pharma/ramnog\")"},{"path":"https://hta-pharma.github.io/ramnog/reference/dummy_fn.html","id":null,"dir":"Reference","previous_headings":"","what":"Title — dummy_fn","title":"Title — dummy_fn","text":"exists import data.table","code":""},{"path":"https://hta-pharma.github.io/ramnog/reference/dummy_fn.html","id":"ref-usage","dir":"Reference","previous_headings":"","what":"Usage","title":"Title — dummy_fn","text":"","code":"dummy_fn()"},{"path":"https://hta-pharma.github.io/ramnog/reference/dummy_fn.html","id":"value","dir":"Reference","previous_headings":"","what":"Value","title":"Title — dummy_fn","text":"Nothing.","code":""}]
+[{"path":"https://hta-pharma.github.io/ramnog/LICENSE.html","id":null,"dir":"","previous_headings":"","what":"MIT License","title":"MIT License","text":"Copyright (c) 2024 Novo Nordisk /S, Danish company registration . 24256790 Permission hereby granted, free charge, person obtaining copy software associated documentation files (“Software”), deal Software without restriction, including without limitation rights use, copy, modify, merge, publish, distribute, sublicense, /sell copies Software, permit persons Software furnished , subject following conditions: copyright notice permission notice shall included copies substantial portions Software. SOFTWARE PROVIDED “”, WITHOUT WARRANTY KIND, EXPRESS IMPLIED, INCLUDING LIMITED WARRANTIES MERCHANTABILITY, FITNESS PARTICULAR PURPOSE NONINFRINGEMENT. EVENT SHALL AUTHORS COPYRIGHT HOLDERS LIABLE CLAIM, DAMAGES LIABILITY, WHETHER ACTION CONTRACT, TORT OTHERWISE, ARISING , CONNECTION SOFTWARE USE DEALINGS SOFTWARE.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"context---why-debugging-is-different","dir":"Articles","previous_headings":"","what":"Context - why debugging is different","title":"Debugging","text":"{chef} pipeline, execution environment managed {targets}, take place working environment. side-effect, straightforward reproduce errors trace back source. Specifically: target {targets} pipeline run new R session closes upon completion hitting error. means working environment clean every run, beneficial reproducibility can make harder debug state led error might readily accessible. {targets} uses caching mechanism avoid re-running successful tasks. feature enhances efficiency, can make debugging tricky. Understanding whether bug due current code cached results might straightforward Sometimes, error messages {targets} pipeline can cryptic informative, making harder figure ’s going wrong. Debugging often requires interactively running code inspect objects states. However, {targets} designed non-interactive batch (sometimes parallel) execution, can make interactive debugging less straightforward. example, just insert browser() function errored like interactive debugging.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"chef-style-debugging","dir":"Articles","previous_headings":"","what":"{chef} style debugging","title":"Debugging","text":"common errors due errors stemming improper user inputs (e.g. user-supplied functions generate input ADaM datasets, contain statistical methods). debug , easiest programmer access state program time errored-. Errors stemming user function split two types: Firstly, relating function formals specifically whether function inputs match supplied {chef}. Secondly, errors arise evaluation function validation output. errors can come bug functions causing crashing runtime, functions return invalid output.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"input-errors","dir":"Articles","previous_headings":"{chef} style debugging","what":"Input errors","title":"Debugging","text":"Input errors stems mismatch expected arguments function arguments {chef} supplies. Errors domain stem improperly defined statistical functions instance statistical functions applied wrong statistical types endpoint specification. function user can define {chef} supplies predefined set arguments (data, statistics, criteria). arguments always supplied, function must either exhaustive function definition, recommended include dots (…) function definition allow functions ignore arguments, required specific function.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"examples","dir":"Articles","previous_headings":"{chef} style debugging > Input errors","what":"Examples:","title":"Debugging","text":"-defined function function require arguments supplied. example, expect---supplied argument specific_arg clearly described well arguments {chef} supplies (study_metadata) full function argument specification. -defined function function explicitly require supplied arguments also doesn’t dots (…) included catch surplus arguments. -defined example function expect supplied study_metadata argument. example also shows optional arguments (default values) displayed.","code":"# Given a data_prepare function: my_data <- function(study_metadata, specific_arg){   #... }  # Would give rise to the following error:  Function (my_data) of type (data_prepare) expects argument(s) which is not supplied:     specific_arg Supplied arguments:     study_metadata Expected arguments: (required, [optional])     specific_arg, study_metadata [] # Given a data_prepare function: my_data <- function(arg_w_default=2){   #... }  # Would give rise to the following error:  Function (my_data) of type (data_prepare) is supplied arguments it does not expect:     study_metadata Supplied arguments:     study_metadata Expected arguments: (required, [optional])      [my_def_arg] Either state all supplied args explicitely or use dots (...) as a passthrough (recommended)."},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"evaluation-and-validation-errors","dir":"Articles","previous_headings":"{chef} style debugging","what":"Evaluation and validation errors","title":"Debugging","text":"{chef} built-helpers provide user state pipeline user-supplied function errors-. using helpers, programmer can access workspace (.e., objects functions) point error. can debug interactively like normal R debugging. broad terms {chef} supply user function input parameters lead erroneous evaluation. {chef} supply debugging sessions function crashes function output compliant. (Statistical output, Criterion output) failures evaluation error message contain keyword EVALUATE non-conforming outputs result errors VALIDATE keyword. Sample error messages can seen following.","code":"# Error message wrt. validation  Error during evaluation of: log(1) Failed to VALIDATE function output with error: Expected (data.table::data.table) Found: numeric  # Error message wrt. evaluation  Error during evaluation of: P-interaction Failed to EVALUATE function with error:  Error : argument \"cell_index\" is missing, with no default"},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"debugging-session","dir":"Articles","previous_headings":"{chef} style debugging > Evaluation and validation errors","what":"Debugging session:","title":"Debugging","text":"evaluation fails output non-compliant {chef} collect inputs function function write file new environment object. debugging environment written debugging subfolder current working directory .RDS file. problem can investigated using built-function chef::load_debug_session() loading directly session using readRDS().","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"debugging-example","dir":"Articles","previous_headings":"{chef} style debugging > Evaluation and validation errors","what":"Debugging example:","title":"Debugging","text":"example review debugging flow faulty stat method. define endpoint single statistic. setup pipeline described End--End examples. execute pipeline tar_make() can check output messages target run: ▶ indicates starting target evaluation ●, ✖ indicates successful failed evaluation respectably. Console output can see pipeline failed evaluation target-step ep_stat_by_strata_by_trt. Furthermore, can view Last error get meaningful error message. shows failed evaluate function aliased n_sub error message Calculation impossible can inspect problem running suggested command: - chef::load_debug_session('/tmp/RtmpCiXPPf/testproj275bcd76287e8d/debug/n_sub.Rdata')  can play around function, given supplied inputs. toy example simply function throws error - simple error fix. However, tool provides possiblity explore tinker functions context fail pipeline. NB. mentioned console message - remember update changes source code!","code":"mk_ep_def <- function() {               ep  <- chef::mk_endpoint_str(                 ..., # The rest of the input parameters.                 stat_by_strata_by_trt = list(\"n_sub\" = n_sub),               )             } tar_make() Loading required package: targets ▶ start target ep ● built target ep [0.038 seconds] ▶ start target ep_id ● built target ep_id [0.001 seconds] (...) # We ignore some other upstream target evaluations. ▶ start target ep_stat_by_strata_by_trt ✖ error target ep_stat_by_strata_by_trt ▶ end pipeline [3.556 seconds] Error: Error running targets::tar_make()   Error messages: targets::tar_meta(fields = error, complete_only = TRUE)   Debugging guide: https://books.ropensci.org/targets/debugging.html   How to ask for help: https://books.ropensci.org/targets/help.html   Last error:  Error during evaluation of: n_sub Failed to EVALUATE function with error:  Error in fn_callable[[1]](dat = dat[[1]], treatment_var = treatment_var,  :    Calculation impossible!  --- Debugging session created: Launch with:  chef::load_debug_session('/tmp/RtmpCiXPPf/testproj275bcd76287e8d/debug/n_sub.Rdata') ---"},{"path":"https://hta-pharma.github.io/ramnog/articles/debugging.html","id":"targets-style-debugging","dir":"Articles","previous_headings":"","what":"Targets style debugging","title":"Debugging","text":"several approaches debugging pipeline erroring . Find much details targets manual: clean R session, load inputs target producing error via tar_load(names = c(<target_names)) debug function target interactively like debug R function Run tar_make(callr_function = NULL) instead usual tar_make. executes pipeline current R session rather seperate R process, can debug interactively using standard R debugging approaches.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_contribute.html","id":"gitflow","dir":"Articles","previous_headings":"","what":"Gitflow","title":"Contributing","text":"packages use Gitflow way working. Please see linked resource details work style. Specifically package always main branch functioning deployable.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_contribute.html","id":"how-to-add-a-feature-bugfix","dir":"Articles","previous_headings":"Gitflow","what":"How to add a feature / bugfix","title":"Contributing","text":"Create new branch main, lets say call feature_A Develop, commit, push feature_A done, make draft PR feature_A main. trigger CI/CD pipelines checks run. Check output CI/CD checks make requisit changes feature_A pipeline runs wihout errors, mark draft PR ready review assign reviewer PR approved, chose option squash merge commits. option summarize changes feature/bug fix address. Delete source branch (feature_A)","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_contribute.html","id":"dod","dir":"Articles","previous_headings":"","what":"Definition of done","title":"Contributing","text":"feature branch defined done ready PR (pull request) main branch properly tested. Please see Quality Control vignette detailed information entails. Briefly, testing consists : Unit-tests test basic functionality Integration testing ensure features work together Passing CI/CD developing, example, new statistical function {chefStats} must checked unit tests. Additionally, previous unit-tests integration tests need pass. can check running devtools::test() respective packages. Note: Integration testing mostly resides ramnog package, need run devtools::test() well","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_contribute.html","id":"devops-pre-commit-and-git-actions","dir":"Articles","previous_headings":"","what":"DevOps: Pre-commit and Git-actions","title":"Contributing","text":"ramnog ecosystem uses pre-commit hooks Git-Actions ensure code quality consistency. Configuration Pre-commit well Git-action workflows hosted {ramnog} package consumed packages. Idealy, DevOps configuration hosted seperate repository, now {ramnog} package.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_contribute.html","id":"pre-commit","dir":"Articles","previous_headings":"DevOps: Pre-commit and Git-actions","what":"Pre-commit","title":"Contributing","text":"Pre-commit tool runs checks code commited. configured .pre-commit-config.yaml file root repository.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_devops.html","id":"github-actions","dir":"Articles","previous_headings":"","what":"GitHub Actions","title":"DevOps","text":"GitHub Actions set automated workflows automatically triggered specific events repository. ramnog ecosystem, git actions used run tests, check test coverage, check package dependencies build documentation site. two major flows setup ecosystem. Check Package Dependencies License check R-CMD check Test (unittest coverage) Git-leaks (Check secrets) Build check pkg. tarball Pull-requests main new sub-site created github pages. run tag created main branch.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_devops.html","id":"system-setup","dir":"Articles","previous_headings":"GitHub Actions","what":"System setup","title":"DevOps","text":"workflows shared across {ramnog} ecosystem flows hosted ramnog repository referenced {Chef*} repositories. logic stored consumer repositories trigger workflows. actual workflow stored ramnog repository .github/workflows folder. workflow references multiple subflows local external repositories.","code":"on:   push:     branches: [main, stage, dev]   pull_request:     branches: [main, stage, dev]   workflow_dispatch:  name: Check Package 📦  jobs:   check:     name: Checks (from ramnog)     uses: hta-pharma/ramnog/.github/workflows/Check-package.yaml@main on:   push:     branches: [main, stage, dev]   pull_request:     branches: [main, stage, dev]   workflow_dispatch:   workflow_call:  name: Check Package 📦  jobs:   audit:     name: Audit Dependencies 🕵️‍♂️     uses: insightsengineering/r.pkg.template/.github/workflows/audit.yaml@main    licenses:     name: License Check 🃏     uses: insightsengineering/r.pkg.template/.github/workflows/licenses.yaml@main    check:     name: RMD check 📦     uses: ./.github/workflows/R-CMD-check.yaml    test:     name: Test 🧪     uses: ./.github/workflows/Test.yaml    gitleaks:     name: gitleaks 💧     uses: insightsengineering/r.pkg.template/.github/workflows/gitleaks.yaml@main     with:       check-for-pii: false #Currently fails on R packages (not that the test check fails, but that the test fails to run.)"},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_devops.html","id":"updating-the-workflows","dir":"Articles","previous_headings":"GitHub Actions > System setup","what":"Updating the workflows","title":"DevOps","text":"workflows updated ramnog repository. workflows consumer repositories simply consume workflows ramnog repository main branch. possible, keep updates workflows within two main workflows (Check Package Release Package). Thus, updates consumer repositories needed. - Remember can use conditions inside workflows run different steps based event-type. Note: testing update may want create new branch ramnog repository update workflows consumer repositories point new branch. allow test changes without affecting main branch.","code":"on:   push:     branches: [main, stage, dev]   pull_request:     branches: [main, stage, dev]   workflow_dispatch:  name: Check Package 📦  jobs:   check:     name: Checks (from ramnog)     uses: hta-pharma/ramnog/.github/workflows/Check-package.yaml@feature/new-workflow # <-- new branch"},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_devops.html","id":"pre-commit-hooks","dir":"Articles","previous_headings":"","what":"Pre-commit hooks","title":"DevOps","text":"Pre-commit hooks tool allows run set checks code commit . built standard git hooks, easier manage share across projects. pre-commit hooks run every commit. hooks fail, commit aborted. downside need install pre-commit package machine activate given repository. Individual setup pre-commit hooks described pre-commit documentation. Install pre-commit Individual user space (use pip pipx installed) Install pre-commit hooks repository. NOTE: needs run root repository Run files check works: pre-commit hook requires python environment. python installed, can install using conda pyenv. python3 installed get error python available may need specify python3 used. can done either following (asumming linux environment):","code":"pipx install pre-commit pre-commit install pre-commit run --all-files # Create a symlink for python3 in the python bin sudo ln -s /usr/bin/python3 /usr/bin/python # Install the python-is-python3 package sudo apt-get install python-is-python3"},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_devops.html","id":"usage","dir":"Articles","previous_headings":"Pre-commit hooks","what":"Usage","title":"DevOps","text":"hooks run whenever create commit. hooks fail, commit aborted. hooks automatically fix issues, others report issues. Even hooks automatically fix issues, still need add changes commit commit .","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_devops.html","id":"system-setup-1","dir":"Articles","previous_headings":"Pre-commit hooks","what":"System setup","title":"DevOps","text":"pre-commits run defined .pre-commit-config.yaml file root repository. file exists repositories ramnog ecosystem. {chef}, {chefStats}, {chefCriteria} pre-commit configs identical points org-hook ramnog. org-hook custom hook defined ramnog repository. hook defined hooks folder ramnog repository. org-hook points script runs pre-commit using standard pre-commit config template. template likewise stored ramnog repository.","code":"repos: -   repo: https://github.com/hta-pharma/ramnog     rev: v0.1.1     hooks:     -   id: org-hook -   id: org-hook     name: org-wide hooks     language: script     entry: ./run-org-hooks     verbose: true     require_serial: true repos: -   repo: https://github.com/lorenzwalthert/precommit     rev: v0.4.0     hooks:      -   id: readme-rmd-rendered     -   id: parsable-R     -   id: no-browser-statement     (...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/dev_devops.html","id":"updating-the-run-hooks","dir":"Articles","previous_headings":"Pre-commit hooks > System setup","what":"Updating the run hooks:","title":"DevOps","text":"order update hooks, need update shared-pre-commit-config.yaml file ramnog repository. Furthemore, hooks consumer repos (chef*) needs updated version hosted ramnog. need either tag ramnog repository following changes update rev chef*/.pre-commit-config.yaml files new tag. Updating rev chef*/.pre-commit-config.yaml file trigger pre-commit hooks update hooks next commit. command pre-commit auto-update can used update consumer hooks. Alternatively can update consumer rev latest commit hash ramnog repository.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_overview.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Endpoint Specification","text":"endpoint specifications comprise central input {chef} contains instructions produce statistics endpoints. specifications contain instructions data use endpoint, statistics include, statistics calculated, group population, criteria must met include endpoint final dossier. specifications must organized data table row contains endpoint specification rows processed independently may represent one endpoints. One single specification may contain instructions produce multiple endpoints e.g. different severity levels system organ classes. result processing endpoint specifications {chef} set statistics, structured long-formatted data table can processed downstream modules e.g. format raw results endpoint tables. scope {chef}. Many components endpoint specifications consist references custom functions outside {chef}, provide high flexibility defining endpoints. endpoint specifications associated custom functions must supplied user inputs {chef} part package. endpoint definition created calling function mk_endpoint_str. endpoint parameters required others optional. Optional parameters default set empty calling mk_endpoint_str, user type endpoint parameters every time required relevant endpoint specification. summary, endpoint specifications can considered cooking recipe along set ingredients (trial data) cooking tools (custom functions) handed chef, {chef}, prepares endpoints. details internal steps {chef} see Getting Started Pipelines.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_adam_data.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"ADaM Data","text":"endpoint needs generated single analysis data set containing information one ADaM data sets. analysis data set created custom ADaM function written trial programmer referenced endpoint specification via data_prepare parameter. ADaM function contains instructions ADaM data sets join, join, custom variables e.g., new groupings, create (). three requirements ADaM function: must exactly one input argument study_metadata endpoint specification parameter, preferably 1-element list, contains relevant information study may used read ADaM data sets. information needed, leave study_metadata unused function set empty list() endpoint specification. must return data.table object. work data.table, can converting tibble data.frame object data.table object end function via data.table::.data.table(my_data_frame). returned table must contain ADAM variables (derived variables) mentioned endpoint specification also subject ID variable USUBJID. summary, analysis data set generation controlled following two parameters endpoint specification: data_prepare: Reference custom function returns single consolidated analysis table contains ADaM data needed endpoint. study_metadata: Object containing study specifics relevant reading ADAM data. Must parsed input ADaM ADSL functions. May empty needed.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_adam_data.html","id":"ex-1-1","dir":"Articles","previous_headings":"","what":"ADaM Data","title":"ADaM Data","text":"example ADAM function first reads ADSL data table {pharmaverseadam}, filters two treatment arms, enriches derived variable. merges enriched ADSL ADAE {pharmaverseadam} return single table ADaM information ADSL ADAE:","code":"# Example of ADaM function that merges information from ADSL and ADAE mk_adam_ex1_1 <- function(study_metadata) {    # Read ADSL from {pharmaverseadam}    adsl <- data.table::as.data.table(pharmaverseadam::adsl)      # Filter treatment arms   adsl <- adsl[adsl$TRT01A %in% c('Placebo', 'Xanomeline High Dose')]      # New derived ADSL variable    adsl[, AGEGR2 := data.table::fcase(AGE < 70, \"AGE < 70\",                                      AGE >= 70, \"AGE >= 70\")]      # Read ADAE from {pharmaverseadam}   adae <- data.table::as.data.table(pharmaverseadam::adae)      # Merge ADSL and ADAE   adae_out <-     merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"), with =                        F], by = \"USUBJID\", all = TRUE)   return(adae_out) }"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_adam_data.html","id":"ex-1-2","dir":"Articles","previous_headings":"","what":"ADaM Data","title":"ADaM Data","text":"might also cases information several ADAM tables required endpoint. example returns ADaM information example addition baseline body weight extracted ADVS. information three ADaM tables merged returned single analysis data set:","code":"# Example of ADaM function that merges information from three ADaM tables mk_adam_ex1_2 <- function(study_metadata) {      # Read ADSL from {pharmaverseadam}    adsl <- data.table::as.data.table(pharmaverseadam::adsl)      # Filter treatment arms   adsl <- adsl[adsl$TRT01A %in% c('Placebo', 'Xanomeline High Dose')]      # New derived ADSL variable    adsl[, AGEGR2 := data.table::fcase(AGE < 70, \"AGE < 70\",                                      AGE >= 70, \"AGE >= 70\")]      # Read ADAE from {pharmaverseadam}   adae <- data.table::as.data.table(pharmaverseadam::adae)    # Read ADVS from {pharmaverseadam}   advs <- data.table::as.data.table(pharmaverseadam::advs)      # Identify baseline body weight   advs_bw <- advs[advs$PARAMCD == \"WEIGHT\" & advs$VISIT == \"BASELINE\"]      # Create new variable bw_baseline   advs_bw[[\"bw_baseline\"]] <- advs_bw[[\"AVAL\"]]      # Merge ADSL, ADAE and baseline body weight from ADVS   ax_out <-     merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"), with = F],            by = \"USUBJID\", all.x = TRUE) |>      merge(x=_, advs_bw[, c(\"bw_baseline\", \"USUBJID\")], by = \"USUBJID\", all.x = TRUE)      return(ax_out) }"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_adam_data.html","id":"ex-1-3","dir":"Articles","previous_headings":"Examples","what":"Ex 1.3","title":"ADaM Data","text":"ADaM functions, defined, need linked corresponding endpoint specifications via data_prepare parameter. creation endpoint specification facilitated mk_endpoint_str function wherein data_prepare parameter established. following example, mk_adam_ex1_2 function utilized produce analysis data intended endpoint.","code":"# Example of endpoint specification of ADaM function. # The dots must be replaced with other required parameters. ep_spec_ex1_3  <- chef::mk_endpoint_str(   data_prepare = mk_adam_ex1_2,   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Endpoint Events","text":"Events records analysis data defined ‘positives’ context endpoint. example, adverse events certain type may events one endpoint, demographic endpoint subjects analysis data (comply period filter) events. Since events bounded rows analysis data, entity event fixed. depends analysis data. may e.g. set visits, measurements, subjects. endpoint definition event controlled via following endpoint specification parameters: period_var: Name flag variable analysis data set indicates record contained required time slot event. period_value: value period_var indicates record required time slot. endpoint_filter: optional parameter contains free text endpoint filter adds period filter defined period_var period_value. group_by: optional parameter splits analysis data exclusive groups injected endpoint. adds narrowing endpoint events disregards events outside group specific endpoint. Let us investigate parameters affect set events exposed endpoint. Initially, input data returned data_prepare filtered create analysis data using population filter c.f. Analysis population. Next, endpoint events analysis data identified according filters . Within endpoint , cell statistics also slices analysis data e.g. strata treatment arm combinations. strata work independently event definition, within strata may event non-events. See Strata details. illustrations depict four possible cases combining event specification parameters.    Case : period filter (period_value period_var) applied case analysis data records meet period filter events. Case B: period filter endpoint filter active. Case C: setup case addition endpoint grouping events restricted within group element. case illustrates setup one group levels (group 1). Case D: setup case B addition endpoint grouping events restricted within group element. case illustrates setup one group levels (group 1).","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html","id":"ex-4-1","dir":"Articles","previous_headings":"","what":"Endpoint Events","title":"Endpoint Events","text":"three examples syntax supplying period filter, endpoint filter endpoint grouping, respectively, endpoint specification.","code":"# Example of partial endpoint specification with period filter ep_spec_ex4_1_1  <- chef::mk_endpoint_str(   period_var = \"ANL01FL\"   period_value = \"Y\",   ...)  # Example of partial endpoint specification with endpoint filtering ep_spec_ex4_1_2  <- chef::mk_endpoint_str(   endpoint_filter = 'ASEV == \"MILD\"',   ...)  # Example of partial endpoint specification with endpoint grouping ep_spec_ex4_1_3  <- chef::mk_endpoint_str(   group_by = list(list(AESEV = c(\"MILD\", \"MODERATE\", \"SERVERE\"))),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html","id":"ex-4-2","dir":"Articles","previous_headings":"","what":"Endpoint Events","title":"Endpoint Events","text":"may also state group levels lazy manner case group levels analysis data set applied. useful group variable many levels e.g., system organ class (SOC), leave certain group levels. example supply lazy grouping SOC.","code":"# Example of partial endpoint specification with lazy endpoint grouping ep_spec_ex4_2  <- chef::mk_endpoint_str(   group_by = list(list(AESOC = c())),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html","id":"ex-4-3","dir":"Articles","previous_headings":"","what":"Endpoint Events","title":"Endpoint Events","text":"case want combine groups multiple variables can state dimension grouping group_by parameter. useful e.g., generating endpoint combination adverse event severity SOC exemplified lazy grouping:","code":"# Example of partial endpoint specification with lazy endpoint grouping on multiple variables ep_spec_ex4_3  <- chef::mk_endpoint_str(   group_by = list(list(AESEV = c(), AESOC = c())),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_event_def.html","id":"ex-4-4","dir":"Articles","previous_headings":"","what":"Endpoint Events","title":"Endpoint Events","text":"continuation previews example, interested mild adverse events can replace grouping AESEV endpoint filter filters AESEV.","code":"# Example of partial endpoint specification with endpoint filter and lazy grouping ep_spec_ex4_4  <- chef::mk_endpoint_str(   endpoint_filter = 'ASEV == \"MILD\"',   group_by = list(list(AESOC = c())),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_label.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Endpoint Label","text":"endpoint user option specify label describes content endpoint. parsed string via endpoint_label parameter endpoint specification. string may contain references parameters endpoint specification encapsulated <>. references dynamically evaluated respective values parameters. endpoint label unique endpoint, references optional. Label referencing particularly useful endpoint grouping applied, resolves endpoint group level. case may dynamically refer group level present endpoints. dynamic labeling may also convenient way refer important parameters identifies endpoint e.g., pop_var, period_var endpoint_filter.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_label.html","id":"ex-6-1","dir":"Articles","previous_headings":"","what":"Endpoint Label","title":"Endpoint Label","text":"Suppose define endpoint specification endpoint safety analysis population (SAFFL = \"Y\") grouped adverse event severity AESEV three levels: MILD, MODERATE, SERVERE. Note assumes SAFFL AESEV variables analysis data set. setup may specify dynamic endpoint label refer population severity: resolve three endpoints following labels:","code":"# Example of partial endpoint specification of analysis population ep_spec_ex6_1  <- chef::mk_endpoint_str(   pop_var = \"SAFFL\",   pop_value = \"Y\",   group_by = list(list(AESEV = c())),   endpoint_label = \"Example: <pop_var> - <AESEV> adverse events\",   ...) \"Example: SAFFL - MILD adverse events\" \"Example: SAFFL - MODERATE adverse events\" \"Example: SAFFL - SERVERE adverse events\""},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_label.html","id":"ex-6-2","dir":"Articles","previous_headings":"","what":"Endpoint Label","title":"Endpoint Label","text":"extension previous example, suppose want consider subjects ages 18-64 years via age group variable AGEGR1 analysis data set. addition, want update endpoint label refer filter. look like : , resolve three endpoints now endpoint labels:","code":"# Example of partial endpoint specification of analysis population ep_spec_ex6_2  <- chef::mk_endpoint_str(   pop_var = \"SAFFL\",   pop_value = \"Y\",   endpoint_filter = \"AGEGR1 == '18-64'\",   group_by = list(list(AESEV = c())),   endpoint_label =     \"Example: <pop_var> - <AESEV> adverse events / <endpoint_filter>\",   ...) \"Example: SAFFL - MILD adverse events / AGEGR1 == '18-64'\" \"Example: SAFFL - MODERATE adverse events / AGEGR1 == '18-64'\" \"Example: SAFFL - SERVERE adverse events / AGEGR1 == '18-64'\""},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_label.html","id":"ex-6-3","dir":"Articles","previous_headings":"","what":"Endpoint Label","title":"Endpoint Label","text":"provide references endpoint label, simply returned static string. Hence, modify label previous example follows: get following endpoint labels:","code":"# Example of partial endpoint specification of analysis population ep_spec_ex6_3  <- chef::mk_endpoint_str(   pop_var = \"SAFFL\",   pop_value = \"Y\",   endpoint_filter = \"AGEGR1 == '18-64'\",   group_by = list(list(AESEV = c())),   endpoint_label = \"Example of a fixed endpoint label\",   ...) \"Example of a fixed endpoint label\" \"Example of a fixed endpoint label\" \"Example of a fixed endpoint label\""},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_population_def.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Analysis Population","text":"analysis data constitutes records input data set relevant statistics endpoint. can controlled via following endpoint specification parameters filters analysis data analysis population: pop_var: Name flag variable input data set indicates record eligible analysis endpoint. pop_value: value pop_var indicates record eligible. custom_pop_filter: optional parameter contains free text population filter adds filter formed pop_var pop_value. Recommended ad-hoc testing different sub populations. approach records irrelevant endpoint removed early stage, relevant analysis population exposed statistical functions criteria functions.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_population_def.html","id":"ex-3-1","dir":"Articles","previous_headings":"","what":"Analysis Population","title":"Analysis Population","text":"example specification analysis data using safety population flag (assumed present input data returned data_prepare:","code":"# Example of partial endpoint specification of population filter ep_spec_ex3_1  <- chef::mk_endpoint_str(   pop_var = \"SAFFL\",   pop_value = \"Y\",   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_population_def.html","id":"ex-3-2","dir":"Articles","previous_headings":"","what":"Analysis Population","title":"Analysis Population","text":"population may filtered adding custom filter. example, addition population filter example may add custom filter subjects aged least 55 years inlcuded population.","code":"# Example of partial endpoint specification of analysis population ep_spec_ex3_2  <- chef::mk_endpoint_str(   pop_var = \"SAFFL\",   pop_value = \"Y\",   custom_pop_filter = \"AGE >= 55\",   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_strata_def.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Strata","text":"stratify_by endpoint parameter specifies variables analysis data set population sliced endpoint granular comparison treatment arm effects. key properties stratify_by parameter: stratify_by list() object list may empty stratification needed. Regardless whether srtata specified (meet strata criteria c.f. Criteria methods) , endpoint statistics always derived total analysis population endpoint. total can considered special stratum one level. stratum values required stratify_by. relevant statistics applied stratum. strata variables applied independently, .e. strata combined. e.g. stratify age group gender, cross combination SEX=\"F\" & AGEGR=\"<65\". cross combinations two stratum variables B required, either: Create derived variable data_prepare combines B stratify new variable. Use endpoint_filter group_by group filter data stratify B within group level.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_strata_def.html","id":"ex-5-1","dir":"Articles","previous_headings":"","what":"Strata","title":"Strata","text":"","code":"# Example of partial endpoint specification with a strata definition ep_spec_ex5_2  <- chef::mk_endpoint_str(   stratify_by = list(c(\"SEX\")),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_strata_def.html","id":"ex-5-2","dir":"Articles","previous_headings":"","what":"Strata","title":"Strata","text":"Two strata set:","code":"# Example of partial endpoint specification with a strata definition ep_spec_ex5_2  <- chef::mk_endpoint_str(   stratify_by = list(c(\"SEX\", \"AGEGGR1\")),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_strata_def.html","id":"ex-5-3","dir":"Articles","previous_headings":"","what":"Strata","title":"Strata","text":"strata, case total present endpoint:","code":"# Example of partial endpoint specification with a strata definition ep_spec_ex5_3  <- chef::mk_endpoint_str(   stratify_by = list(),   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_treatment_arms.html","id":"overview","dir":"Articles","previous_headings":"","what":"Overview","title":"Treatment Arms","text":"treatment arm specifications used split analysis data separate treatment arm assessed compared endpoint. endpoint specification following two parameters must set: treatment_var: Name variable analysis data set contains treatment arms. treatment_refval: value treatment_var corresponds reference/intervention. may used asymmetric statistics compare treatment effects.","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/articles/ep_spec_treatment_arms.html","id":"ex-2-1","dir":"Articles","previous_headings":"","what":"Treatment Arms","title":"Treatment Arms","text":"example partial endpoint specification treatment arm specifications:","code":"# Example of endpoint specification of treatment arms. ep_spec_ex2_1  <- chef::mk_endpoint_str(   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   ...)"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"endpoint-types","dir":"Articles","previous_headings":"","what":"Endpoint types","title":"Endpoint Catalog","text":"Binary type 1 Binary type 2 Demographics Continuous outcomes  endpoints , note endpoint specification must contain statistics strata treatment arm (N, n, %), strata across treatment arms (RR, , P-value) across strata treatment arms (P-value interaction) must calculated two strata (Age, Sex). statistical functions come library statistical functions {chefStats}. assume endpoint concerns adverse events must applied full safety population set (SAFFL=\"Y\"). also need functions produce clinical data pass data_prepare. Since examlple analyses adverse events, need version ADAE dataset. exact nature clinical dataset differ project--project, library data prep functions can source . Instead define example functions : Let us consider different variations endpoint specification cases . examples demonstrate apply statistics either full population, grouping system organ class (SOCs) severity, filtered severity. Note set SOCs trimmed according endpoint criterion function (ep_crit_min_subev_by_trt), SOCs least 5 subjects events least one treatment arm included. criteria function come library criteria functions found {chefCriteria}.  get results match table , can group endpoints AESOC, within AESOC grouping, stratify AEDECOD. framing , can see need statistic (n number subjects event E number events) every combination endpoint group (AESOC) stratification level (AEDECOD). statistical functions come chefStats. assume endpoint concerns adverse events must applied full safety population set (SAFFL=\"Y\"). also need functions produce clinical data pass data_prepare. Since examlple analyses adverse events, need version ADAE dataset. exact nature clinical dataset differ project--project, library data prep functions can source . Instead define example functions :  table contains continuous variables (Age, Body Weight Baseline) categorical variables (Age Group, Sex) different statistics applied. endpoint split two endpoint specifications, one continuous variables (case 5), one categorical variables (case 6). categorical variables (Age Group Sex), see need statistic stratification level category (e.g. AGEGR1 < 65 AGEGR1 >= 65). clear get results need, need one statistic per stratification level treatment level. Thus supply statistical function stat_by_strata_by_trt argument endpoint specification. continuous variables less obvious. However, consider TOTAL stratification just like age sex, albeit single level, can see also need one statistic per strata level treatment level, use stat_by_strata_by_trt cases single statistical function applied, (chefStats::demographics_continuous() chefStats::demographics_categorical() respectively) compactly supplies required statistics one function call. Alternatively, can define separate functions statistics apply individually endpoint specification. also need functions produce clinical data pass data_prepare. Since example analyzes body weight, need version ADVS dataset. exact nature clinical dataset differ project--project, library data prep functions can source . Instead define example matches needs analysis: show define demographic endpoints continuous variables categorical variables  table contains statistics baseline characteristics, well change--baseline. observe mean SD calculated combination treatment arm, strata (total age), time (baseline, week 8 16). defining time (AVISIT) endpoint grouping can obtain statistics one endpoint specification. implies : mean SD calculated treatment strata levels (stat_by_strata_by_trt) analysis data columns containing baseline (VALUE_BASELINE) change baseline column (VALUE_CHANGE). Number subjects (N) also calculated treatment strata level (stat_by_strata_by_trt). endpoint grouping (AVISIT) Hedge’s G calculated strata level across treatment arms (stat_by_strata_across_trt). also need functions produce clinical data pass data_prepare. Since example analyses laboratory data, need version ADLB dataset. exact nature clinical dataset differ project--project, library data prep functions can source . Instead define example matches needs analysis: endpoint specification showing summary statistics baseline change baseline shown ","code":"# Merge ADSL and ADAE from {pharmaverseadam} mk_adae <- function(study_metadata) {    # Read ADSL   adsl <- data.table::as.data.table(pharmaverseadam::adsl)    # Filter treatment arms   adsl <- adsl[adsl$TRT01A %in% c(\"Placebo\", \"Xanomeline High Dose\")]    # New derived ADSL age group variable   adsl[, AGEGR2 := data.table::fcase(AGE < 65, \"AGE < 65\",     AGE >= 65, \"AGE >= 65\",     default = NA   )]    # Read ADAE   adae <- data.table::as.data.table(pharmaverseadam::adae)    # Merge ADSL and ADAE   adam_out <-     merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"),       with =         F     ], by = \"USUBJID\", all = TRUE)    return(adam_out) } # Merge ADSL and ADAE from {pharmaverseadam} mk_adae <- function(study_metadata) {    # Read ADSL   adsl <- data.table::as.data.table(pharmaverseadam::adsl)    # Filter treatment arms   adsl <- adsl[adsl$TRT01A %in% c(\"Placebo\", \"Xanomeline High Dose\")]    # New derived ADSL age group variable   adsl[, AGEGR2 := data.table::fcase(AGE < 65, \"AGE < 65\",     AGE >= 65, \"AGE >= 65\",     default = NA   )]    # Read ADAE   adae <- data.table::as.data.table(pharmaverseadam::adae)    # Merge ADSL and ADAE   adam_out <-     merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"),       with =         F     ], by = \"USUBJID\", all = TRUE)    return(adam_out) } ep_spec <- chef::mk_endpoint_str(     data_prepare = mk_adae,     pop_var = \"SAFFL\",     pop_value = \"Y\",     treatment_var = \"TRT01A\",     treatment_refval = \"Xanomeline High Dose\",     group_by = list(list(AESOC = c())),     stratify_by = list(c(\"AEDECOD\")),     stat_by_strata_by_trt = list(chefStats::n_subj_event,                                  chefStats::n_event)   ) # Merge ADSL and ADVS from {pharmaverseadam} mk_advs <- function(study_metadata) {    # Read ADSL   adsl <- data.table::as.data.table(pharmaverseadam::adsl)    # Filter treatment arms   adsl <- adsl[adsl$TRT01A %in% c(\"Placebo\", \"Xanomeline High Dose\")]    # New derived ADSL age group variable   adsl[, AGEGR2 := data.table::fcase(AGE < 65, \"AGE < 65\",     AGE >= 65, \"AGE >= 65\",     default = NA   )]   # Read ADVS   advs <- data.table::as.data.table(pharmaverseadam::advs)    # Identify baseline body weight   advs_bw <- advs[advs$PARAMCD == \"WEIGHT\" & advs$VISIT == \"BASELINE\"]    # Create new variable BW_BASELINE   advs_bw[[\"BW_BASELINE\"]] <- advs_bw[[\"AVAL\"]]    # Merge ADSL, ADAE and baseline body weight from ADVS   adam_out <-     merge(adsl, advs_bw[, c(\"BW_BASELINE\", \"USUBJID\")], by = \"USUBJID\", all.x = TRUE)    return(adam_out) } # Merge ADSL and ADLB from {pharmaverseadam} mk_adlb <- function(study_metadata) {   # Read ADSL   adsl <- data.table::as.data.table(pharmaverseadam::adsl)    # Filter treatment arms   adsl <-     adsl[adsl$TRT01A %in% c(\"Placebo\", \"Xanomeline High Dose\")]    # New derived ADSL age group variable   adsl[, AGEGR2 := data.table::fcase(AGE < 65, \"AGE < 65\",     AGE >= 65, \"AGE >= 65\",     default = NA   )]    # Read ADLB   adlb_0 <- data.table::as.data.table(pharmaverseadam::adlb)   adlb_1 <- adlb_0[adlb_0[[\"PARAMCD\"]] == \"SODIUM\" &       adlb_0[[\"AVISIT\"]] %in% c(\"Baseline\", \"Week 8\", \"Week 16\"), ]    adlb2 <-     merge(adlb_1,       adlb_1[adlb_1$AVISIT == \"Baseline\", c(\"USUBJID\", \"AVAL\")],       by = \"USUBJID\", all.x = TRUE     )    adlb2[[\"VALUE_BASELINE\"]] <- adlb2[[\"AVAL.y\"]]   adlb2[[\"VALUE_CHANGE\"]] <- adlb2[[\"AVAL.x\"]] - adlb2[[\"AVAL.y\"]]    # Merge ADSL and ADLB   adam_out <-     merge(adsl, adlb2[, c(       \"USUBJID\",       \"PARAMCD\",       \"AVISIT\",       \"VALUE_BASELINE\",       \"VALUE_CHANGE\",       \"ANL01FL\"     )], by = \"USUBJID\", all.x = TRUE)    return(adam_out) } chef::mk_endpoint_str(   data_prepare = mk_adlb,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_value = \"Y\",   group_by = list(list(AVISIT = c())),   stratify_by = list(c(\"AGEGR2\")),   stat_by_strata_by_trt = list(     \"n_sub\" = chefStats::n_subj,     \"mean: VALUE_BASELINE\" = c(chefStats::mean_value, var = \"VALUE_BASELINE\"),     \"mean: VALUE_CHANGE\" = c(chefStats::mean_value, var = \"VALUE_CHANGE\"),     \"sd: VALUE_BASELINE\" = c(chefStats::sd_value, var = \"VALUE_BASELINE\"),     \"sd: VALUE_CHANGE\" = c(chefStats::sd_value, var = \"VALUE_CHANGE\")   ),   stat_by_strata_across_trt = list(hedgesg),   endpoint_label = \"Baseline and change from baseline on SODIUM - <AVISIT>\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-1-adverse-events-base-form","dir":"Articles","previous_headings":"Endpoint types","what":"Case 1: Adverse events (base form)","title":"Endpoint Catalog","text":"","code":"ep_spec <- chef::mk_endpoint_str(   data_prepare = mk_adae,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   stratify_by = list(c(\"AGEGR2\", \"SEX\")),   stat_by_strata_by_trt = list(     chefStats::n_subj,     chefStats::n_subj_event,     cheStats::p_subj_event   ),   stat_by_strata_across_trt = list(     chefStats::RR,     chefStats::OR,     chefStats::p_val   ),   stat_across_strata_across_trt = list(chefStats::pval_interaction),   endpoint_label = \"Adverse events - <treatment_var>\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-2-adverse-events-grouped-by-system-organ-class","dir":"Articles","previous_headings":"Endpoint types","what":"Case 2: Adverse events grouped by system organ class","title":"Endpoint Catalog","text":"","code":"ep_spec <- chef::mk_endpoint_str(   data_prepare = mk_adae,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   group_by = list(list(AESOC = c())),   stratify_by = list(c(\"AGEGR2\", \"SEX\")),   stat_by_strata_by_trt = list(     chefStats::n_subj,     chefStats::n_subj_event,     cheStats::p_subj_event   ),   stat_by_strata_across_trt = list(     chefStats::RR,     chefStats::OR,     chefStats::p_val   ),   stat_across_strata_across_trt = list(chefStats::pval_interaction),   crit_endpoint = list(     c(       ep_crit_min_subev_by_trt,       min_n_subev = 5,       requirement_type = \"any\"     )   ),   endpoint_label = \"Adverse events - <AESOC> - <treatment_var>\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-3-mild-adverse-events-grouped-by-system-organ-class","dir":"Articles","previous_headings":"Endpoint types","what":"Case 3: Mild adverse events grouped by system organ class","title":"Endpoint Catalog","text":"","code":"ep_spec <- chef::mk_endpoint_str(   data_prepare = mk_adae,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   endpoint_filter = 'ASEV == \"MILD\"',   group_by = list(list(AESOC = c())),   stratify_by = list(c(\"AGEGR2\", \"SEX\")),   stat_by_strata_by_trt = list(     chefStats::n_subj,     chefStats::n_subj_event,     cheStats::p_subj_event   ),   stat_by_strata_across_trt = list(     chefStats::RR,     chefStats::OR,     chefStats::p_val   ),   stat_across_strata_across_trt = list(chefStats::pval_interaction),   crit_endpoint = list(     c(       ep_crit_min_subev_by_trt,       min_n_subev = 5,       requirement_type = \"any\"     )   ),   endpoint_label = \"Mild adverse events - <treatment_var>\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-4-adverse-events-grouped-by-severity-and-system-organ-class","dir":"Articles","previous_headings":"Endpoint types","what":"Case 4: Adverse events grouped by severity and system organ class","title":"Endpoint Catalog","text":"","code":"ep_spec <- chef::mk_endpoint_str(   data_prepare = mk_adae,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   group_by = list(list(ASEV = c(), AESOC = c())),   stratify_by = list(c(\"AGEGR2\", \"SEX\")),   stat_by_strata_by_trt = list(     chefStats::n_subj,     chefStats::n_subj_event,     cheStats::p_subj_event   ),   stat_by_strata_across_trt = list(     chefStats::RR,     chefStats::OR,     chefStats::p_val   ),   stat_across_strata_across_trt = list(chefStats::pval_interaction),   crit_endpoint = list(     c(       ep_crit_min_subev_by_trt,       min_n_subev = 5,       requirement_type = \"any\"     )   ),   endpoint_label = \"<ASEV> adverse events - <AESOC> - <treatment_var>\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-1-baseline-characteristics-of-analysis-population-continuous-variables","dir":"Articles","previous_headings":"Endpoint types","what":"Case 1: Baseline characteristics of analysis population (continuous variables)","title":"Endpoint Catalog","text":"","code":"chef::mk_endpoint_str(   data_prepare = mk_advs,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   stat_by_strata_by_trt = list(     c(demographics_continuous,       var = \"AGE\"     ),     c(demographics_continuous,       var = \"BW_BASELINE\"     )   ),   endpoint_label = \"Demographics endpoint (categorical measures)\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/example_ep_spec.html","id":"case-2-baseline-characteristics-of-analysis-population-categorical-variables","dir":"Articles","previous_headings":"Endpoint types","what":"Case 2: Baseline characteristics of analysis population (categorical variables)","title":"Endpoint Catalog","text":"collect two endpoint specifications cover complete endpoint:","code":"chef::mk_endpoint_str(   data_prepare = mk_advs,   treatment_var = \"TRT01A\",   treatment_refval = \"Xanomeline High Dose\",   pop_var = \"SAFFL\",   pop_value = \"Y\",   stratify_by = list(c(\"AGEGR2\", \"SEX\")),   stat_by_strata_by_trt = list(c(demographics_counts)),   endpoint_label = \"Demographics endpoint (categorical measures)\" ) ep_spec <- rbind(ep_spec_pt1, ep_spec_pt2)"},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"introduction","dir":"Articles","previous_headings":"","what":"Introduction","title":"Criteria Methods","text":"vignette provides short introduction idea analysis criteria. analysis request authorities detail overall set endpoints, irrespective underlying study data. example, might request analysis serious adverse events system organ class, gender. analyses may contain many cells zeros, low counts. ensure analyses contain meaningfully amounts data included, request may additionally include certain criteria inclusion analysis, threshold minimum number records, events, subjects. logic analysis inclusion criteria handled functions supplied crit_endpoint, crit_by_strata_by_trt, crit_by_strata_across_trt arguments defining endpoint mk_endpoints_str().","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"criteria-levels","dir":"Articles","previous_headings":"","what":"Criteria levels","title":"Criteria Methods","text":"Currently, {chef} supports analysis inclusion criteria three parts analysis output, colors corresponding figure : entire endpoint stat_by_strata_by_trt stat_by_strata_across_trt stat_across_strata_across_trt  criteria functions hierarchical; failure meet criteria Level (Entire Endpoint) implies automatic failure Levels B C. Similarly, passing Level failing Level B results failure Level C. endpoint satisfy certain criterion, associated statistical functions execute reduce compute time. instance, endpoint meet criteria Level B, strata across treatment arms analyses performed. However, analyses Totals still proceed. important note criteria optional. every endpoint definition needs incorporate three levels criteria. analyses may criteria, others might require criteria endpoint strata. NOTE crit_by_strata_across_trt criterion gate-keep stat_by_strata_across_trt stat_across_strata_across_trt (stippled box). stat_across_strata_across_trt seen lower hierarchical criteria ladder stat_by_strata_across_trt - however seperate criterion time therefore included default.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"function-formals","dir":"Articles","previous_headings":"","what":"Function formals","title":"Criteria Methods","text":"Chef supplies number parameters criterion functions. parameters vary according statistical method. Note crit_by_strata_by_trt, crit_by_strata_across_trt formals functions identical.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"input-specifications","dir":"Articles","previous_headings":"Function formals","what":"Input specifications","title":"Criteria Methods","text":"criteria functions served broad set parameters. reflects need flexibility criteria functions. flexibility allows set criteria affect specific stratum based specific stratum information shared across multiple strata. allows create criteria functions target one stratum act across whole strata: Criteria1 requires endpoint strata GENDER must balanced. (ie approx 50/50 distribution.) (requires stratify_by parameter) Criteria2 requires endpoint strata (GENDER, AGE) must balanced. (requires stratify_by parameter) may also also design criteria endpoints, includes case enough subjects relevant strata. See Examples NB Similar stat methods require criteria function include ellipses (...) wildcard parameter. convenience, since need explicitly state used parameters function definition. However, importantly ensure criteria function define today also work tomorrow, {chef} may supply parameters criteria functions. Endpoint criteria functions Strata criteria functions","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"output-specifications","dir":"Articles","previous_headings":"Function formals","what":"Output specifications","title":"Criteria Methods","text":"output criteria function must simple boolean (TRUE FALSE)","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"example-functions","dir":"Articles","previous_headings":"Function formals","what":"Example functions","title":"Criteria Methods","text":"two examples showcasing write criteria functions. within scope {chef} package provide library criteria functions. Endpoint criteria functions Strata criteria functions Generic criteria function: Allows control endpoint inclusion based count subjects events arms. function generic can specified mk_endpoint_str curried beforehand (Stat methods-Currying) include across strata treatment arm analysis least X subjects events treatment arm. requirement_type==“” just single cell (stratum + treatment arm) needs included.","code":"ep_criteria.treatment_arms_minimum_unique_event_count <- function(     dat,     event_index,     treatment_var,     subjectid_var,     minimum_event_count,     requirement_type = c(\"any\", \"all\")     ...     )   # rows with events   dat_events <- dat[J(event_index),]    # Bolean of whether the count of unique subjects    # within each treatment arm is above the minimum count.     dat_lvl_above_threshold <- dat_events[     ,      list(\"is_above_minimum\" = data.table::uniqueN(subjectid_var)>=minimum_event_count),      by=treatment_var   ]      if requirement_type == \"any\":     return( any(dat_lvl_above_threshold$V1) )   return( all(dat_lvl_above_threshold$V1) ) ep_strata_criteria.strata_treatment_arm_minimum_unique_count <- function(     dat,     event_index,     treatment_var,     subjectid_var,     strata_var,     minimum_event_count,     requirement_type = c(\"any\", \"all\")     ...     )   # rows with events   dat_events <- dat[J(event_index),]    # Bolean of whether the count of unique subjects    # within each treatment arm is above the minimum count.     dat_lvl_above_threshold <- dat_events[     ,      list(\"is_above_minimum\" = data.table::uniqueN(subjectid_var)>=minimum_event_count),      by=c(treatment_var, strata_var)   ]      if requirement_type == \"any\":     return( any(dat_lvl_above_threshold$is_above_minimum) )   return( all(dat_lvl_above_threshold$is_above_minimum) )"},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_criteria.html","id":"applying-criteria-functions","dir":"Articles","previous_headings":"Function formals","what":"Applying criteria functions","title":"Criteria Methods","text":"Criteria functions supplied mk_endpoint_str function used gatekeep statistical function run. example endpoint : look population event E_XYZ. interested endpoint see least 5 subjects arms event E_XYZ. interested getting descriptive statistic strata (say GENDER, AGEGRP) levels within least 1 subject. Finally, run across treatment arm statistics least 5 subject stratum treatment arm. requirements/gates implemented currying functions given Examples section.","code":"# R/project_criteria.R # Curry the general criteria functions from [Examples](#examples)  crit_accept_endpoint.5_subjects_any_treatment_arm <- purrr:partial(   ep_criteria.treatment_arms_minimum_unique_event_count,   minimum_event_count = 5,   requirement_type = \"any\" )  crit_strata.1_subject_all_treatment_strata <- purrr:partial(   ep_sg_criteria.sg_treatment_arm_minimum_unique_count,   minimum_event_count = 1,   requirement_type = \"all\" )  crit_strata.5_subject_all_treatment_strata <- purrr:partial(   ep_sg_criteria.sg_treatment_arm_minimum_unique_count,   minimum_event_count = 5,   requirement_type = \"all\" )  # R/project_endpoints.R  endpoint_XYZ  <- chef::mk_endpoint_str(   ..., # Setting the rest of the inputs   crit_endpoint = list(crit_accept_endpoint.5_subjects_any_treatment_arm),   crit_by_strata_by_trt = list(crit_strata.1_subject_all_treatment_strata),   crit_by_strata_across_trt = list(crit_strata.5_subject_all_treatment_strata) )"},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_stat.html","id":"statistical-method-types","dir":"Articles","previous_headings":"","what":"Statistical method types","title":"Statistical Methods","text":"{chef} framework categorizes statistical functions three main categories depending operate stratification levels treatment levels. Operations can either done per stratification level treatment level, can operate across levels. Figure 1 shows typical table safety analysis color codes result based function type creates : Figure 1 Table 1 provides description three function types, color coded outputs produce table 1 : Table 1 function type also determines function applied. example figure 1, stat_by_strata_by_trt function called combination stratification level treatment level, well TOTALS treatment level: SEX == “MALE” & TRT == “TreatmentA” SEX == “FEMALE” & TRT == “TreatmentA” SEX == “MALE” & TRT == “TreatmentB” SEX == “FEMALE” & TRT == “TreatmentB” AGE == “<65” & TRT == “TreatmentA” AGE == “>=65” & TRT == “TreatmentA” AGE == “<65” & TRT == “TreatmentB” AGE == “>=65” & TRT == “TreatmentB” TOTAL_ == “total” & TRT == “TreatmentA” TOTAL_ == “total” & TRT == “TreatmentB” Whereas stat_across_strata_across_trt called per stratification “group”, .e.: strata_var == “SEX” strata_var == “AGE”","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/methods_stat.html","id":"project-specific-statistical-functions","dir":"Articles","previous_headings":"","what":"Project-specific statistical functions","title":"Statistical Methods","text":"need statistical function exist {chefStats}, writing adding chefStats package, way can used others - please see documentation chefStats package details. sometimes might make sense. case can always reference custom function endpoint specification stored R/ directory project folder. example want new function my_custom_stats_function type stat_by_strata_by_trt . first define function: ’s save R/, can reference endpoint specification just like chefStats functions: Important: custom function relies external packages, need add packages packages.R file R/.","code":"my_custom_function <- function(     # function arguments here   ){   # Function does something here } chef::mk_endpoint_str(   ..., # other arguments to mk_endpoint_str   stat_by_strata_by_trt = my_custom_function)"},{"path":"https://hta-pharma.github.io/ramnog/articles/qc.html","id":"unit-testing","dir":"Articles","previous_headings":"","what":"Unit testing","title":"Quality control for ramnog ecosystem","text":"package contains unit tests functionality package responsible . means, example, responsibility unit-tests {chefStats} ensure statistical functions written chefStats produce result supposed produce.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/qc.html","id":"integration-testing","dir":"Articles","previous_headings":"","what":"Integration testing","title":"Quality control for ramnog ecosystem","text":"Integration testing verifies framework produces expected results integration testing done via {testthat} framework, essentially unit-tests cover many different units goal compare results analysis run via ramnog expected results done manual calculation analysis. example, unit test ensure results endpoint definition defined run via chef match calculated manually","code":"testthat::test_that(\"Valide stats when one strata level is not found\",           {             # SETUP -------------------------------------------------------------------             testr::create_local_project()             mk_adae <- function(study_metadata) {               adsl <- pharmaverseadam::adsl |> data.table::setDT()               adae <- pharmaverseadam::adae |> data.table::setDT()               adae_out <-                 merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"), with =                                    F], by = \"USUBJID\", all = TRUE)               adae_out[TRT01A %in% c('Placebo', 'Xanomeline High Dose'),]             }             mk_ep_def <- function() {               chef::mk_endpoint_str(                 study_metadata = list(),                 pop_var = \"SAFFL\",                 pop_value = \"Y\",                 treatment_var = \"TRT01A\",                 treatment_refval = \"Xanomeline High Dose\",                 stratify_by = list(c(\"SEX\")),                 data_prepare = mk_adae,                 endpoint_label = \"A\",                 custom_pop_filter = \"SEX == 'F'\",                 group_by = list(list(AESEV = c())),                 stat_by_strata_by_trt = list(                   \"N\" = chefStats::n_subj,                   \"E\" = chefStats::n_event,                   \"N subj E\" = chefStats::n_subj_event                 ),                 stat_by_strata_across_trt = list(\"RR\" = chefStats::RR,                                                  \"OR\" = chefStats::OR),                 stat_across_strata_across_trt = list(\"P-interaction\" = chefStats::p_val_interaction)               )             }              chef::use_chef(               pipeline_dir = \"pipeline\",               r_functions_dir = \"R/\",               pipeline_id = \"01\",               mk_endpoint_def_fn = mk_ep_def,               mk_adam_fn = list(mk_adae)             )             # ACT ---------------------------------------------------------------------             targets::tar_make()             targets::tar_load(ep_stat)             # EXPECT ------------------------------------------------------------------             # Manually calculated expected results             x <- mk_adae(study_metadata = NULL)             # Relative Risk             actual <-               ep_stat[endpoint_group_filter == \"AESEV == \\\"SEVERE\\\"\" &                         fn_name == \"RR\" &                         stat_filter == \"SEX == \\\"F\\\"\" & stat_result_label == \"RR\", stat_result_value]             x1 <- x[SEX == \"F\" & SAFFL == \"Y\"]             x1[, event := FALSE]             x1[AESEV == \"SEVERE\", event := TRUE] |> data.table::setorder(-event)             x1_unique <-               unique(x1, by = \"USUBJID\", fromLast = FALSE)             two_by_two <-               x1_unique[, .N, by = .(TRT01A, event)][order(TRT01A, event)]                          # Outcome, exposed             a <-               two_by_two[TRT01A == \"Xanomeline High Dose\" &                            (event), N]                           # No outcome, exposed             b <-               two_by_two[TRT01A == \"Xanomeline High Dose\" &                            !(event), N]                            # Outcome, not exposed             c <-               two_by_two[TRT01A == \"Placebo\" &                            (event), N]                          # No outcome, not exposed             d <-               two_by_two[TRT01A == \"Placebo\" &                            !(event), N]                           expected <- (a / sum(a, b)) / (c / sum(c, d))             expect_identical(actual, expected)              # Number of Events             actual <-               ep_stat[endpoint_group_filter == \"AESEV == \\\"SEVERE\\\"\" &                         fn_name == \"E\" &                         strata_var == \"SEX\"]             expected <-               x1[(event), .N, by = .(TRT01A)][order(TRT01A)][, as.double(N)]             expect_identical(actual$stat_result_value, expected)           }) #> v Setting active project to '/tmp/RtmpmDDHCp/testproj1c7a4756a670' #> v Writing 'R/packages.R' #> v Writing 'pipeline/pipeline_01.R' #> * Edit 'pipeline/pipeline_01.R' #> * Edit 'R/mk_adae.R' #> i Renaming \"mk_ep_def\" to \"mk_endpoint_def.R\" #>  #> * Edit 'R/mk_endpoint_def.R' #> Loading required package: targets #> ▶ dispatched target ep #> ● completed target ep [0.03 seconds] #> ▶ dispatched target ep_id #> ● completed target ep_id [0.009 seconds] #> ▶ dispatched branch ep_fn_map_a9f94f07 #> ● completed branch ep_fn_map_a9f94f07 [0.032 seconds] #> ● completed pattern ep_fn_map #> ▶ dispatched target user_def_fn #> ● completed target user_def_fn [0.003 seconds] #> ▶ dispatched target study_data #> ● completed target study_data [0.038 seconds] #> ▶ dispatched target fn_map_tibble #> ● completed target fn_map_tibble [0.005 seconds] #> ▶ dispatched branch ep_and_data_a9f94f07 #> ● completed branch ep_and_data_a9f94f07 [0.008 seconds] #> ● completed pattern ep_and_data #> ▶ dispatched branch fn_map_f5f06580 #> ● completed branch fn_map_f5f06580 [0.001 seconds] #> ● completed pattern fn_map #> ▶ dispatched branch analysis_data_container_5d792ea5 #> ● completed branch analysis_data_container_5d792ea5 [0 seconds] #> ● completed pattern analysis_data_container #> ▶ dispatched branch ep_with_data_key_5d792ea5 #> ● completed branch ep_with_data_key_5d792ea5 [0 seconds] #> ● completed pattern ep_with_data_key #> ▶ dispatched branch ep_expanded_0ccac0a6 #> ● completed branch ep_expanded_0ccac0a6 [0.035 seconds] #> ● completed pattern ep_expanded #> ▶ dispatched branch ep_event_index_74b91187 #> ● completed branch ep_event_index_74b91187 [0.009 seconds] #> ● completed pattern ep_event_index #> ▶ dispatched branch ep_crit_endpoint_fafa2a2e #> ● completed branch ep_crit_endpoint_fafa2a2e [0.003 seconds] #> ● completed pattern ep_crit_endpoint #> ▶ dispatched branch ep_crit_by_strata_by_trt_8436637b #> ● completed branch ep_crit_by_strata_by_trt_8436637b [0.009 seconds] #> ● completed pattern ep_crit_by_strata_by_trt #> ▶ dispatched branch ep_crit_by_strata_across_trt_821fa7bd #> ● completed branch ep_crit_by_strata_across_trt_821fa7bd [0.004 seconds] #> ● completed pattern ep_crit_by_strata_across_trt #> ▶ dispatched branch ep_prep_by_strata_across_trt_71db754a #> ● completed branch ep_prep_by_strata_across_trt_71db754a [0.038 seconds] #> ● completed pattern ep_prep_by_strata_across_trt #> ▶ dispatched branch ep_prep_across_strata_across_trt_71db754a #> ● completed branch ep_prep_across_strata_across_trt_71db754a [0.016 seconds] #> ● completed pattern ep_prep_across_strata_across_trt #> ▶ dispatched branch ep_prep_by_strata_by_trt_71db754a #> ● completed branch ep_prep_by_strata_by_trt_71db754a [0.064 seconds] #> ● completed pattern ep_prep_by_strata_by_trt #> ▶ dispatched target ep_rejected #> ● completed target ep_rejected [0.001 seconds] #> ▶ dispatched branch ep_stat_by_strata_across_trt_c1669b51 #> ● completed branch ep_stat_by_strata_across_trt_c1669b51 [0.124 seconds] #> ● completed pattern ep_stat_by_strata_across_trt #> ▶ dispatched branch ep_stat_across_strata_across_trt_81193129 #> ● completed branch ep_stat_across_strata_across_trt_81193129 [0.032 seconds] #> ● completed pattern ep_stat_across_strata_across_trt #> ▶ dispatched branch ep_stat_by_strata_by_trt_2f3f8ab5 #> ● completed branch ep_stat_by_strata_by_trt_2f3f8ab5 [0.045 seconds] #> ● completed pattern ep_stat_by_strata_by_trt #> ▶ dispatched target ep_stat_nested #> ● completed target ep_stat_nested [0 seconds] #> ▶ dispatched target ep_stat #> ● completed target ep_stat [0.013 seconds] #> ▶ ended pipeline [0.762 seconds] #> v Restoring original working directory: '/home/runner/work/ramnog/ramnog/vignettes/' #> v Setting active project to '<no active project>' #> v Deleting temporary project: '/tmp/RtmpmDDHCp/testproj1c7a4756a670/' #> Test passed"},{"path":"https://hta-pharma.github.io/ramnog/articles/qc.html","id":"cicd","dir":"Articles","previous_headings":"","what":"CI/CD","title":"Quality control for ramnog ecosystem","text":"Please see DevOps vignette details CI/CD infrastructure.","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"set-up-project-infrastructure","dir":"Articles","previous_headings":"","what":"1. Set up project infrastructure","title":"Quick Start","text":"assumes set RStudio project (equivalent). done , first. setup chef project need: functions used make ADaM data ingested chef pipeline R function produces endpoint specification object analysis/statistical functions sourced R packages (like chefStats chefCriteria) script containing library() calls package needed pipeline run pipeline/ directory targets pipeline(s) /defined targets.yml file tracking different pipelines file file structure look like : {chef} convenience function set infrastructure : sets following file structure: now need know file R/ . _targets.yml pipeline_01.R explanation, see vignette(\"pipeline\").","code":"<R-project dir>/     |-- R/         |--- mk_endpoint_definition.R         |--- mk_adam.R         |--- packages.R     |-- pipeline/         |--- pipeline_01.R     |-- _targets.yaml library(chef) chef::use_chef(   pipeline_id = \"01\" )"},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"specify-an-endpoint","dir":"Articles","previous_headings":"","what":"1. Specify an endpoint","title":"Quick Start","text":"Endpoint specifications need created inside function, case function defined mk_endpoint_definition.R endpoint created using chef::mk_endpoint_str() function. explanation specify endpoints, see vignette(\"endpoint_definitions\"). specify minimal working endpoint based adae dataset supplied {pharmaverseadam}. modifying R/mk_endpoint_definition.R file looks like : might notice couple things specification: stratify_by field refer variable called AGEGR2, however ADAE dataset {pharmaverseadam} contain variable. derive variable inside mk_adae (see next section).","code":"mk_endpoint_def <- function() {   chef::mk_endpoint_str(     study_metadata = list(),     pop_var = \"SAFFL\",     pop_value = \"Y\",     treatment_var = \"TRT01A\",     treatment_refval = \"Xanomeline High Dose\",     stratify_by = list(c(\"AGEGR2\")),     data_prepare = mk_adae,     endpoint_label = \"A\",     custom_pop_filter = \"TRT01A %in% c('Placebo', 'Xanomeline High Dose')\",     stat_by_strata_by_trt = list(\"N_subj_event\" = c(chefStats::n_subj_event))   ) }"},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"define-the-input-dataset","dir":"Articles","previous_headings":"","what":"2. Define the input dataset","title":"Quick Start","text":"also need provide chef ADAE input data set corresponds endpoint specified . read make data sets, see vignette(\"mk_adam\"). can see strata based AGEGR2, can derived AGE variable ADSL. now, write simple ADaM function mk_adae merges ADSL data set (enriched AGEGR2) onto ADAE data set, thereby creating input data set.","code":"mk_adae <- function(study_metadata) {   adae <- data.table::as.data.table(pharmaverseadam::adae)   adsl <- data.table::as.data.table(pharmaverseadam::adsl)   adsl[, AGEGR2 := data.table::fcase(     AGE < 70, \"AGE < 70\",     AGE >= 70, \"AGE >= 70\"   )]   adae_out <-     merge(adsl, adae[, c(setdiff(names(adae), names(adsl)), \"USUBJID\"),       with =         F     ], by = \"USUBJID\", all = TRUE)   adae_out[] }"},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"define-the-analysis-methods","dir":"Articles","previous_headings":"","what":"3. Define the analysis methods","title":"Quick Start","text":"Now specified endpoint analyzed, defined analysis data set {chef}, need define analysis . goal analysis count number events experiencing event. need define function makes calculations, give function chef. want result per treatment arm - strata combination, must provide function stat_by_strata_by_trt argument endpoint specification. already argument set chefStats::n_subj_event example endpoint specification ","code":""},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"run-the-analysis-pipeline","dir":"Articles","previous_headings":"","what":"4. Run the analysis pipeline","title":"Quick Start","text":"Now inputs defined, can run pipeline. achieved call tar_make() {targets} package. Targets show steps pipeline executed long step took: , see results, load cached step pipeline corresponding results. case ep_stat, load sessions object call Now ep_stat R object like . Thus can look results simply running However, lot extra data included object, lets look column subsection first 5 rows:","code":"targets::tar_make() ## Loading required package: targets ## ▶ dispatched target ep ## ● completed target ep [0.03 seconds] ## ▶ dispatched target ep_id ## ● completed target ep_id [0.01 seconds] ## ▶ dispatched branch ep_fn_map_c85cfecb ## ● completed branch ep_fn_map_c85cfecb [0.032 seconds] ## ● completed pattern ep_fn_map ## ▶ dispatched target user_def_fn ## ● completed target user_def_fn [0.003 seconds] ## ▶ dispatched target study_data ## ● completed target study_data [0.035 seconds] ## ▶ dispatched target fn_map_tibble ## ● completed target fn_map_tibble [0.005 seconds] ## ▶ dispatched branch ep_and_data_c85cfecb ## ● completed branch ep_and_data_c85cfecb [0.009 seconds] ## ● completed pattern ep_and_data ## ▶ dispatched branch fn_map_9cf81814 ## ● completed branch fn_map_9cf81814 [0.001 seconds] ## ● completed pattern fn_map ## ▶ dispatched branch analysis_data_container_a4b422b1 ## ● completed branch analysis_data_container_a4b422b1 [0 seconds] ## ● completed pattern analysis_data_container ## ▶ dispatched branch ep_with_data_key_a4b422b1 ## ● completed branch ep_with_data_key_a4b422b1 [0 seconds] ## ● completed pattern ep_with_data_key ## ▶ dispatched branch ep_expanded_e741f3f8 ## ● completed branch ep_expanded_e741f3f8 [0.019 seconds] ## ● completed pattern ep_expanded ## ▶ dispatched branch ep_event_index_5f7976c8 ## ● completed branch ep_event_index_5f7976c8 [0.003 seconds] ## ● completed pattern ep_event_index ## ▶ dispatched branch ep_crit_endpoint_3da7fd1e ## ● completed branch ep_crit_endpoint_3da7fd1e [0.004 seconds] ## ● completed pattern ep_crit_endpoint ## ▶ dispatched branch ep_crit_by_strata_by_trt_1786b781 ## ● completed branch ep_crit_by_strata_by_trt_1786b781 [0.008 seconds] ## ● completed pattern ep_crit_by_strata_by_trt ## ▶ dispatched branch ep_crit_by_strata_across_trt_6a441418 ## ● completed branch ep_crit_by_strata_across_trt_6a441418 [0.004 seconds] ## ● completed pattern ep_crit_by_strata_across_trt ## ▶ dispatched branch ep_prep_by_strata_across_trt_89480a2b ## ● completed branch ep_prep_by_strata_across_trt_89480a2b [0.001 seconds] ## ● completed pattern ep_prep_by_strata_across_trt ## ▶ dispatched branch ep_prep_across_strata_across_trt_89480a2b ## ● completed branch ep_prep_across_strata_across_trt_89480a2b [0.002 seconds] ## ● completed pattern ep_prep_across_strata_across_trt ## ▶ dispatched branch ep_prep_by_strata_by_trt_89480a2b ## ● completed branch ep_prep_by_strata_by_trt_89480a2b [0.034 seconds] ## ● completed pattern ep_prep_by_strata_by_trt ## ▶ dispatched target ep_rejected ## ● completed target ep_rejected [0 seconds] ## ▶ dispatched branch ep_stat_by_strata_across_trt_a72d712a ## ● completed branch ep_stat_by_strata_across_trt_a72d712a [0.001 seconds] ## ● completed pattern ep_stat_by_strata_across_trt ## ▶ dispatched branch ep_stat_across_strata_across_trt_b2713725 ## ● completed branch ep_stat_across_strata_across_trt_b2713725 [0 seconds] ## ● completed pattern ep_stat_across_strata_across_trt ## ▶ dispatched branch ep_stat_by_strata_by_trt_9535dd36 ## ● completed branch ep_stat_by_strata_by_trt_9535dd36 [0.01 seconds] ## ● completed pattern ep_stat_by_strata_by_trt ## ▶ dispatched target ep_stat_nested ## ● completed target ep_stat_nested [0.001 seconds] ## ▶ dispatched target ep_stat ## ● completed target ep_stat [0.004 seconds] ## ▶ ended pipeline [0.44 seconds] ## targets::tar_load(ep_stat) ep_stat ep_stat[, .(   treatment_var,   treatment_refval,   strata_var,   stat_filter,   stat_result_label,   stat_result_description,   stat_result_qualifiers,   stat_result_value )] |> head() ##    treatment_var     treatment_refval strata_var ##           <char>               <char>     <char> ## 1:        TRT01A Xanomeline High Dose     TOTAL_ ## 2:        TRT01A Xanomeline High Dose     TOTAL_ ## 3:        TRT01A Xanomeline High Dose     AGEGR2 ## 4:        TRT01A Xanomeline High Dose     AGEGR2 ## 5:        TRT01A Xanomeline High Dose     AGEGR2 ## 6:        TRT01A Xanomeline High Dose     AGEGR2 ##                                                 stat_filter stat_result_label ##                                                      <char>            <char> ## 1:                  TOTAL_ == \"total\" & TRT01A == \"Placebo\"                 n ## 2:     TOTAL_ == \"total\" & TRT01A == \"Xanomeline High Dose\"                 n ## 3:               AGEGR2 == \"AGE < 70\" & TRT01A == \"Placebo\"                 n ## 4:              AGEGR2 == \"AGE >= 70\" & TRT01A == \"Placebo\"                 n ## 5:  AGEGR2 == \"AGE < 70\" & TRT01A == \"Xanomeline High Dose\"                 n ## 6: AGEGR2 == \"AGE >= 70\" & TRT01A == \"Xanomeline High Dose\"                 n ##           stat_result_description stat_result_qualifiers stat_result_value ##                            <char>                 <char>             <num> ## 1: Number of subjects with events                   <NA>                86 ## 2: Number of subjects with events                   <NA>                72 ## 3: Number of subjects with events                   <NA>                22 ## 4: Number of subjects with events                   <NA>                64 ## 5: Number of subjects with events                   <NA>                18 ## 6: Number of subjects with events                   <NA>                54"},{"path":"https://hta-pharma.github.io/ramnog/articles/ramnog.html","id":"pass-the-data-on-to-tfl-formatting","dir":"Articles","previous_headings":"","what":"5. Pass the data on to TFL formatting","title":"Quick Start","text":"Now data produced, can pass TFL formatting (outside scope {chef}).","code":""},{"path":"https://hta-pharma.github.io/ramnog/authors.html","id":null,"dir":"","previous_headings":"","what":"Authors","title":"Authors and Citation","text":"Matthew David Phelps. Author. Nicolai Skov Johnsen. Author. Henrik Sparre Spiegelhauer. Author. Christian Haargaard Olsen. Author, maintainer.","code":""},{"path":"https://hta-pharma.github.io/ramnog/authors.html","id":"citation","dir":"","previous_headings":"","what":"Citation","title":"Authors and Citation","text":"Matthew David Phelps, Nicolai Skov Johnsen, Henrik Sparre Spiegelhauer, Christian Haargaard Olsen (2024). ramnog: Facilitating AMNOG style analysis pipelines. R package version 0.1.2,  https://github.com/hta-pharma/ramnog, https://app.codecov.io/gh/hta-pharma/ramnog, https://hta-pharma.github.io/ramnog/.","code":"@Manual{,   title = {ramnog: Facilitating AMNOG style analysis pipelines},   author = {{Matthew David Phelps} and {Nicolai Skov Johnsen} and {Henrik Sparre Spiegelhauer} and {Christian Haargaard Olsen}},   year = {2024},   note = {R package version 0.1.2,  https://github.com/hta-pharma/ramnog, https://app.codecov.io/gh/hta-pharma/ramnog},   url = {https://hta-pharma.github.io/ramnog/}, }"},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/index.html","id":"r-packages-for-amnog-analyses-","dir":"","previous_headings":"","what":"R packages for AMNOG analyses","title":"Facilitating AMNOG style analysis pipelines","text":"Ramnog collection packages setting pipelines AMNOG-style HTA analyses aim ramnog statistician/programmer can set AMNOG-type analyses minimal familiarity R. get started, check Quick Start guide","code":""},{"path":[]},{"path":"https://hta-pharma.github.io/ramnog/index.html","id":"aim","dir":"","previous_headings":"","what":"Aim","title":"Facilitating AMNOG style analysis pipelines","text":"aim {ramnog} programmer write minimal code, programming, set-new AMNOG-type analyses. study, programmer need make, adjust, check following four types code: definition endpoint (group endpoints). set ADaM functions makes modifications existing ADaM datasets (e.g., new age grouping ADSL), makes new ADaM datasets none exist required output. (needed) Define set criteria endpoint included results. library criteria stored companion package {chefCriteria}. specification statistical functions used summarize/analyze data. library functions provided {chefStats} package. core principal frameworks design modularity. core functionality framework resides {chef} change slowly, functionality subject frequent changes sectioned packages ({chefStats} {chefCriteria}).","code":""},{"path":"https://hta-pharma.github.io/ramnog/index.html","id":"contributing","dir":"","previous_headings":"","what":"Contributing","title":"Facilitating AMNOG style analysis pipelines","text":"welcome contributions code base. Please see contributing vignette information contribute.","code":""},{"path":"https://hta-pharma.github.io/ramnog/index.html","id":"installation","dir":"","previous_headings":"","what":"Installation","title":"Facilitating AMNOG style analysis pipelines","text":"packages available install GitHub:","code":"remotes::install_github(\"hta-pharma/ramnog\")"},{"path":"https://hta-pharma.github.io/ramnog/reference/dummy_fn.html","id":null,"dir":"Reference","previous_headings":"","what":"Title — dummy_fn","title":"Title — dummy_fn","text":"exists import data.table","code":""},{"path":"https://hta-pharma.github.io/ramnog/reference/dummy_fn.html","id":"ref-usage","dir":"Reference","previous_headings":"","what":"Usage","title":"Title — dummy_fn","text":"","code":"dummy_fn()"},{"path":"https://hta-pharma.github.io/ramnog/reference/dummy_fn.html","id":"value","dir":"Reference","previous_headings":"","what":"Value","title":"Title — dummy_fn","text":"Nothing.","code":""}]
diff --git a/sitemap.xml b/sitemap.xml
index 9827445..7affd25 100644
--- a/sitemap.xml
+++ b/sitemap.xml
@@ -13,7 +13,10 @@
     <loc>https://hta-pharma.github.io/ramnog/articles/debugging.html</loc>
   </url>
   <url>
-    <loc>https://hta-pharma.github.io/ramnog/articles/dev_git.html</loc>
+    <loc>https://hta-pharma.github.io/ramnog/articles/dev_contribute.html</loc>
+  </url>
+  <url>
+    <loc>https://hta-pharma.github.io/ramnog/articles/dev_devops.html</loc>
   </url>
   <url>
     <loc>https://hta-pharma.github.io/ramnog/articles/ep_overview.html</loc>
@@ -48,6 +51,9 @@
   <url>
     <loc>https://hta-pharma.github.io/ramnog/articles/methods_stat.html</loc>
   </url>
+  <url>
+    <loc>https://hta-pharma.github.io/ramnog/articles/qc.html</loc>
+  </url>
   <url>
     <loc>https://hta-pharma.github.io/ramnog/articles/ramnog.html</loc>
   </url>
@@ -57,9 +63,6 @@
   <url>
     <loc>https://hta-pharma.github.io/ramnog/articles/results_datamodel2tfl.html</loc>
   </url>
-  <url>
-    <loc>https://hta-pharma.github.io/ramnog/articles/validation.html</loc>
-  </url>
   <url>
     <loc>https://hta-pharma.github.io/ramnog/authors.html</loc>
   </url>