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This sounds like a reasonable idea. It can normally be possible to access the underlying numpy array so might not need new code in Innotater, just a bit of thought about how to instantiate the Innotater object.
As a starting point, would you be able to provide some example code for construction of a Pandas dataframe, and then making it clear how you would expect the Innotater to be invoked in that case (which presumably isn't quite working at the moment)?
Pandas is a common library used for data management. It would be very useful to support dataframes on top of numpy arrays.
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