diff --git a/README.md b/README.md
index a71f5ef..060b1d3 100644
--- a/README.md
+++ b/README.md
@@ -20,8 +20,8 @@ Dependencies:
 
 - `gjs (>= 1.70)`
 - `gtk4`
-- `libadwaita`
-- `webkit2gtk4`/`webkit2gtk-5.0`
+- `libadwaita (>= 1.4)`
+- `webkitgtk-6.0`
 
 To install, run `meson builddir && sudo meson install -C builddir`
 
diff --git a/com.github.johnfactotum.QuickLookup.appdata.xml b/com.github.johnfactotum.QuickLookup.appdata.xml
index c28b9b7..fdd1c27 100644
--- a/com.github.johnfactotum.QuickLookup.appdata.xml
+++ b/com.github.johnfactotum.QuickLookup.appdata.xml
@@ -26,6 +26,11 @@
         </screenshot>
     </screenshots>
     <releases>
+        <release version="2.1.0" date="2023-11-12">
+            <description>
+                <p>Upgraded to GNOME 45</p>
+            </description>
+        </release>
         <release version="2.0.0" date="2021-11-14">
             <description>
                 <p>Ported to GTK 4</p>
diff --git a/meson.build b/meson.build
index db62f0d..e44c22e 100644
--- a/meson.build
+++ b/meson.build
@@ -1,5 +1,5 @@
 project('com.github.johnfactotum.QuickLookup',
-    version: '2.0.0',
+    version: '2.1.0',
     meson_version: '>=0.49'
 )
 
@@ -16,8 +16,8 @@ glib2_dep = dependency('glib-2.0')
 gio2_dep = dependency('gio-2.0')
 gjs_dep = dependency('gjs-1.0', version: '>=1.70')
 gtk4_dep = dependency('gtk4')
-webkit_dep = dependency('webkit2gtk-5.0')
-libadwaita_dep = dependency('libadwaita-1')
+webkit_dep = dependency('webkitgtk-6.0')
+libadwaita_dep = dependency('libadwaita-1', version: '>=1.4')
 
 bin_conf = configuration_data()
 bin_conf.set('PACKAGE_VERSION', meson.project_version())
diff --git a/quick-lookup.js b/quick-lookup.js
index 3c54425..c1ec463 100644
--- a/quick-lookup.js
+++ b/quick-lookup.js
@@ -16,9 +16,9 @@
 
 imports.gi.versions.Gio = '2.0'
 imports.gi.versions.Gtk = '4.0'
-imports.gi.versions.WebKit2 = '5.0'
+imports.gi.versions.WebKit = '6.0'
 imports.gi.versions.Adw = '1'
-const { GLib, Gio, Gtk, Gdk, WebKit2, Adw } = imports.gi
+const { GLib, Gio, Gtk, Gdk, WebKit, Adw } = imports.gi
 const System = imports.system
 
 const pkg = {
@@ -72,10 +72,10 @@ const scriptRunner = webView => {
     }
     const manager = webView.get_user_content_manager()
     manager.connect(`script-message-received::handler`, (_, result) => {
-        try { handler(JSON.parse(result.get_js_value().to_string())) }
+        try { handler(JSON.parse(result.to_string())) }
         catch (e) { log(e) }
     })
-    const success = manager.register_script_message_handler('handler')
+    const success = manager.register_script_message_handler('handler', null)
     if (!success) throw new Error('failed to register message handler')
 
     const exec = (func, params) => {
@@ -88,14 +88,14 @@ const scriptRunner = webView => {
             .catch(e => globalThis.webkit.messageHandlers.handler.postMessage(
                 JSON.stringify({ token: "${token}", ok: false, payload: e.message })))`
         const promise = makePromise(token)
-        webView.run_javascript(script, null, () => {})
+        webView.evaluate_javascript(script, -1, null, null, null, () => {})
         return promise
     }
     const eval = exp => new Promise((resolve, reject) =>
-        webView.run_javascript(`JSON.stringify(${exp})`, null, (_, result) => {
+        webView.evaluate_javascript(`JSON.stringify(${exp})`, -1, null, null, null, (_, result) => {
             try {
-                const jsResult = webView.run_javascript_finish(result)
-                const str = jsResult.get_js_value().to_string()
+                const jscValue = webView.evaluate_javascript_finish(result)
+                const str = jscValue.to_string()
                 const value = str !== 'undefined' ? JSON.parse(str) : null
                 resolve(value)
             } catch (e) {
@@ -159,8 +159,8 @@ const wiktionary = ({ word, language }) => fetch('${apiURL}' + word)
 globalThis.wiktionary = wiktionary
 })()`
 
-const webView = new WebKit2.WebView({
-    settings: new WebKit2.Settings({
+const webView = new WebKit.WebView({
+    settings: new WebKit.Settings({
         enable_javascript_markup: false,
         enable_write_console_messages_to_stdout: true,
         allow_universal_access_from_file_urls: true,
@@ -300,9 +300,8 @@ const applicationWindowXml = `<?xml version="1.0" encoding="UTF-8"?><interface>
   <property name="default-width">480</property>
   <property name="title">Quick Lookup</property>
   <property name="content">
-    <object class="GtkBox">
-      <property name="orientation">vertical</property>
-      <child>
+    <object class="AdwToolbarView">
+      <child type="top">
         <object class="AdwHeaderBar">
           <property name="title-widget">
             <object class="GtkSearchEntry" id="query-entry">
@@ -313,7 +312,7 @@ const applicationWindowXml = `<?xml version="1.0" encoding="UTF-8"?><interface>
           <child type="start">
             <object class="GtkButton">
               <property name="icon-name">go-previous-symbolic</property>
-              <property name="tooltip-text">Go back</property>
+              <property name="tooltip-text">Back</property>
               <property name="action-name">win.go-back</property>
             </object>
           </child>
@@ -372,7 +371,7 @@ const applicationWindowXml = `<?xml version="1.0" encoding="UTF-8"?><interface>
           </child>
         </object>
       </child>
-      <child>
+      <child type="bottom">
         <object class="GtkActionBar">
           <child type="center">
             <object class="GtkComboBoxText" id="lang-combo">
diff --git a/screenshot.png b/screenshot.png
index e9dc5de..55b4a3b 100644
Binary files a/screenshot.png and b/screenshot.png differ