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Virstrain build sites cutoff default value. #18

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MTDouglas opened this issue Jul 26, 2024 · 1 comment
Open

Virstrain build sites cutoff default value. #18

MTDouglas opened this issue Jul 26, 2024 · 1 comment

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@MTDouglas
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Hello,

I'm just curious as to what the default value being used in Virstrain_build --sites_cutoff is when no value is specified?

Thanks

@liaoherui
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liaoherui commented Jul 26, 2024

Hi, thanks for using VirStrain!

By default, VirStrain applies "greedy covering algorithm" to find the minimum sites that can distinguish different viral strains automatically (more details can be found in the manuscript). So, this parameter is not used. This parameter may be needed/added when the sequencing depth or quality is low and we want more sites be covered for strain identification.

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