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DESCRIPTION
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DESCRIPTION
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Type: Package
Package: ibdsim2
Title: Simulation of Chromosomal Regions Shared by Family Members
Version: 2.1.2
Authors@R:
person("Magnus Dehli", "Vigeland", , "m.d.vigeland@medisin.uio.no", role = c("aut", "cre"),
comment = c(ORCID = "0000-0002-9134-4962"))
Description: Simulation of segments shared identical-by-descent (IBD) by
pedigree members. Using sex specific recombination rates along the
human genome (Halldorsson et al. (2019)
<doi:10.1126/science.aau1043>), phased chromosomes are simulated for
all pedigree members. Applications include calculation of realised
relatedness coefficients and IBD segment distributions. 'ibdsim2' is
part of the 'pedsuite' collection of packages for pedigree analysis.
A detailed presentation of the 'pedsuite', including a separate
chapter on 'ibdsim2', is available in the book 'Pedigree analysis in
R' (Vigeland, 2021, ISBN:9780128244302). A 'Shiny' app for visualising
and comparing IBD distributions is available at
<https://magnusdv.shinyapps.io/ibdsim2-shiny/>.
License: GPL-3
URL: https://github.com/magnusdv/ibdsim2,
https://magnusdv.github.io/pedsuite/,
https://magnusdv.shinyapps.io/ibdsim2-shiny/
Depends:
R (>= 4.1.0),
pedtools (>= 2.7.1)
Imports:
Rcpp,
ggplot2,
glue,
ribd (>= 1.6.1),
Suggests:
testthat,
shiny,
shinyjs,
lubridate,
patchwork,
zip
LinkingTo:
Rcpp
Encoding: UTF-8
Language: en-GB
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2