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<p><strong>Title:</strong> Store-operated cyclic AMP signalling mediated by STIM1</p>
<p><strong>Year Published:</strong> 2009</p>
<p><strong>Observation:</strong> Chelation of ER Ca2+ enhances cAMP production independent of cytosolic Ca2+. Release of Ca2+ enhances cAMP signaling. STIM1 expression is necessary for store-operated cAMP signaling</p>
<p><strong>Comment:</strong> propose the existence of a pathway in which the content of internal Ca(2+) stores is directly connected to cAMP signalling through a process that involves STIM1.</p>
<p><strong>Citation:</strong> Lefkimmiatis, K., Srikanthan, M., Maiellaro, I., Moyer, M. P., Curci, S., & Hofer, A. M. (2009). Store-operated cyclic AMP signalling mediated by STIM1. Nature Cell Biology, 11(4), 433–42. doi:10.1038/ncb1850</p>
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