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<p><strong>Title:</strong> Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis</p>
<p><strong>Year Published:</strong> 2009</p>
<p><strong>Observation:</strong> GWAS study of 2,323 patients and 9,013 controls. 3 SNPs reached genome wide significance, one in UNC13A, and 2 in chr 9021.2 (closest genes: MOBKL2B, C9ORF72)</p>
<p><strong>Comment:</strong> Identified UNC13A as subceptible gene in ALS</p>
<p><strong>Citation:</strong> Van Es, M. a, Veldink, J. H., Saris, C. G. J., Blauw, H. M., van Vught, P. W. J., Birve, A., … van den Berg, L. H. (2009). Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nature Genetics, 41(10), 1083–7. doi:10.1038/ng.442</p>
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