diff --git a/src/Microsoft.TestPlatform.Client/TestPlatform.cs b/src/Microsoft.TestPlatform.Client/TestPlatform.cs
index 89c3d9d8bf..45ee1303a1 100644
--- a/src/Microsoft.TestPlatform.Client/TestPlatform.cs
+++ b/src/Microsoft.TestPlatform.Client/TestPlatform.cs
@@ -87,7 +87,7 @@ public IDiscoveryRequest CreateDiscoveryRequest(
         loggerManager.Initialize(discoveryCriteria.RunSettings);
 
         IProxyDiscoveryManager discoveryManager = _testEngine.GetDiscoveryManager(requestData, discoveryCriteria, sourceToSourceDetailMap, warningLogger);
-        discoveryManager.Initialize(options?.SkipDefaultAdapters ?? false);
+        discoveryManager.Initialize(GetSkipDefaultAdapters(options, discoveryCriteria.RunSettings));
 
         return new DiscoveryRequest(requestData, discoveryCriteria, discoveryManager, loggerManager);
     }
@@ -110,11 +110,31 @@ public ITestRunRequest CreateTestRunRequest(
         loggerManager.Initialize(testRunCriteria.TestRunSettings);
 
         IProxyExecutionManager executionManager = _testEngine.GetExecutionManager(requestData, testRunCriteria, sourceToSourceDetailMap, warningLogger);
-        executionManager.Initialize(options?.SkipDefaultAdapters ?? false);
+        executionManager.Initialize(GetSkipDefaultAdapters(options, testRunCriteria.TestRunSettings));
 
         return new TestRunRequest(requestData, testRunCriteria, executionManager, loggerManager);
     }
 
+    private static bool GetSkipDefaultAdapters(TestPlatformOptions? options, string? runSettings)
+    {
+        if (options?.SkipDefaultAdapters ?? false)
+        {
+            EqtTrace.Verbose($"TestPlatform.GetSkipDefaultAdapters: Skipping default adapters because of TestPlatform options SkipDefaultAdapters.");
+            return true;
+        }
+
+        RunConfiguration runConfiguration = XmlRunSettingsUtilities.GetRunConfigurationNode(runSettings);
+        var skipping = runConfiguration.SkipDefaultAdapters;
+        if (skipping)
+        {
+            EqtTrace.Verbose($"TestPlatform.GetSkipDefaultAdapters: Skipping default adapters because of RunConfiguration SkipDefaultAdapters.");
+            return true;
+        }
+
+        EqtTrace.Verbose($"TestPlatform.GetSkipDefaultAdapters: Not skipping default adapters SkipDefaultAdapters was false.");
+        return false;
+    }
+
     /// <inheritdoc/>
     public bool StartTestSession(
         IRequestData requestData,
diff --git a/src/Microsoft.TestPlatform.CoreUtilities/FeatureFlag/FeatureFlag.cs b/src/Microsoft.TestPlatform.CoreUtilities/FeatureFlag/FeatureFlag.cs
index 86a7f4c85b..76f8ec1546 100644
--- a/src/Microsoft.TestPlatform.CoreUtilities/FeatureFlag/FeatureFlag.cs
+++ b/src/Microsoft.TestPlatform.CoreUtilities/FeatureFlag/FeatureFlag.cs
@@ -69,6 +69,10 @@ private FeatureFlag() { }
     // Disable forwarding standard output of testhost.
     public const string VSTEST_DISABLE_STANDARD_OUTPUT_FORWARDING = nameof(VSTEST_DISABLE_STANDARD_OUTPUT_FORWARDING);
 
+    // Disable not sharing .NET Framework testhosts. Which will return behavior to sharing testhosts when they are running .NET Framework dlls, and are not disabling appdomains or running in parallel.
+    public const string VSTEST_DISABLE_SHARING_NETFRAMEWORK_TESTHOST = nameof(VSTEST_DISABLE_SHARING_NETFRAMEWORK_TESTHOST);
+
+
     [Obsolete("Only use this in tests.")]
     internal static void Reset()
     {
diff --git a/src/Microsoft.TestPlatform.ObjectModel/PublicAPI/PublicAPI.Shipped.txt b/src/Microsoft.TestPlatform.ObjectModel/PublicAPI/PublicAPI.Shipped.txt
index 74364fb56a..221f78d7d1 100644
--- a/src/Microsoft.TestPlatform.ObjectModel/PublicAPI/PublicAPI.Shipped.txt
+++ b/src/Microsoft.TestPlatform.ObjectModel/PublicAPI/PublicAPI.Shipped.txt
@@ -974,3 +974,5 @@ virtual Microsoft.VisualStudio.TestPlatform.ObjectModel.ValidateValueCallback.In
 Microsoft.VisualStudio.TestPlatform.ObjectModel.Architecture.RiscV64 = 8 -> Microsoft.VisualStudio.TestPlatform.ObjectModel.Architecture
 Microsoft.VisualStudio.TestPlatform.ObjectModel.RunConfiguration.CaptureStandardOutput.get -> bool
 Microsoft.VisualStudio.TestPlatform.ObjectModel.RunConfiguration.ForwardStandardOutput.get -> bool
+Microsoft.VisualStudio.TestPlatform.ObjectModel.RunConfiguration.DisableSharedTestHost.get -> bool
+Microsoft.VisualStudio.TestPlatform.ObjectModel.RunConfiguration.SkipDefaultAdapters.get -> bool
diff --git a/src/Microsoft.TestPlatform.ObjectModel/RunSettings/RunConfiguration.cs b/src/Microsoft.TestPlatform.ObjectModel/RunSettings/RunConfiguration.cs
index 57f198202e..1de0786730 100644
--- a/src/Microsoft.TestPlatform.ObjectModel/RunSettings/RunConfiguration.cs
+++ b/src/Microsoft.TestPlatform.ObjectModel/RunSettings/RunConfiguration.cs
@@ -95,6 +95,7 @@ public RunConfiguration() : base(Constants.RunConfigurationSettingsName)
         ExecutionThreadApartmentState = Constants.DefaultExecutionThreadApartmentState;
         CaptureStandardOutput = !FeatureFlag.Instance.IsSet(FeatureFlag.VSTEST_DISABLE_STANDARD_OUTPUT_CAPTURING);
         ForwardStandardOutput = !FeatureFlag.Instance.IsSet(FeatureFlag.VSTEST_DISABLE_STANDARD_OUTPUT_FORWARDING);
+        DisableSharedTestHost = FeatureFlag.Instance.IsSet(FeatureFlag.VSTEST_DISABLE_SHARING_NETFRAMEWORK_TESTHOST);
     }
 
     /// <summary>
@@ -455,6 +456,16 @@ public bool ResultsDirectorySet
     /// </summary>
     public bool ForwardStandardOutput { get; private set; }
 
+    /// <summary>
+    /// Disables sharing of .NET Framework testhosts.
+    /// </summary>
+    public bool DisableSharedTestHost { get; private set; }
+
+    /// <summary>
+    /// Skips passing VisualStudio built in adapters to the project.
+    /// </summary>
+    public bool SkipDefaultAdapters { get; private set; }
+
     /// <inheritdoc/>
     public override XmlElement ToXml()
     {
@@ -578,6 +589,14 @@ public override XmlElement ToXml()
         forwardStandardOutput.InnerXml = ForwardStandardOutput.ToString();
         root.AppendChild(forwardStandardOutput);
 
+        XmlElement disableSharedTesthost = doc.CreateElement(nameof(DisableSharedTestHost));
+        disableSharedTesthost.InnerXml = DisableSharedTestHost.ToString();
+        root.AppendChild(disableSharedTesthost);
+
+        XmlElement skipDefaultAdapters = doc.CreateElement(nameof(SkipDefaultAdapters));
+        skipDefaultAdapters.InnerXml = SkipDefaultAdapters.ToString();
+        root.AppendChild(skipDefaultAdapters);
+
         return root;
     }
 
@@ -964,6 +983,38 @@ public static RunConfiguration FromXml(XmlReader reader)
                         runConfiguration.ForwardStandardOutput = bForwardStandardOutput;
                         break;
 
+                    case nameof(DisableSharedTestHost):
+                        {
+                            XmlRunSettingsUtilities.ThrowOnHasAttributes(reader);
+                            string element = reader.ReadElementContentAsString();
+
+                            bool boolValue;
+                            if (!bool.TryParse(element, out boolValue))
+                            {
+                                throw new SettingsException(string.Format(CultureInfo.CurrentCulture,
+                                    Resources.Resources.InvalidSettingsIncorrectValue, Constants.RunConfigurationSettingsName, boolValue, elementName));
+                            }
+
+                            runConfiguration.DisableSharedTestHost = boolValue;
+                            break;
+                        }
+
+                    case nameof(SkipDefaultAdapters):
+                        {
+                            XmlRunSettingsUtilities.ThrowOnHasAttributes(reader);
+                            string element = reader.ReadElementContentAsString();
+
+                            bool boolValue;
+                            if (!bool.TryParse(element, out boolValue))
+                            {
+                                throw new SettingsException(string.Format(CultureInfo.CurrentCulture,
+                                    Resources.Resources.InvalidSettingsIncorrectValue, Constants.RunConfigurationSettingsName, boolValue, elementName));
+                            }
+
+                            runConfiguration.SkipDefaultAdapters = boolValue;
+                            break;
+                        }
+
                     default:
                         // Ignore a runsettings element that we don't understand. It could occur in the case
                         // the test runner is of a newer version, but the test host is of an earlier version.
diff --git a/src/Microsoft.TestPlatform.TestHostProvider/Hosting/DefaultTestHostManager.cs b/src/Microsoft.TestPlatform.TestHostProvider/Hosting/DefaultTestHostManager.cs
index ca4e20243e..9d5fd5e4ef 100644
--- a/src/Microsoft.TestPlatform.TestHostProvider/Hosting/DefaultTestHostManager.cs
+++ b/src/Microsoft.TestPlatform.TestHostProvider/Hosting/DefaultTestHostManager.cs
@@ -58,7 +58,7 @@ public class DefaultTestHostManager : ITestRuntimeProvider2
     private readonly IEnvironment _environment;
     private readonly IDotnetHostHelper _dotnetHostHelper;
     private readonly IEnvironmentVariableHelper _environmentVariableHelper;
-
+    private bool _disableAppDomain;
     private Architecture _architecture;
     private Framework? _targetFramework;
     private ITestHostLauncher? _customTestHostLauncher;
@@ -199,10 +199,10 @@ public virtual TestProcessStartInfo GetTestHostProcessStartInfo(
             testhostProcessPath = Path.Combine(currentWorkingDirectory, "..", testHostProcessName);
         }
 
-        if (!Shared)
+        if (_disableAppDomain)
         {
-            // Not sharing the host which means we need to pass the test assembly path as argument
-            // so that the test host can create an appdomain on startup (Main method) and set appbase
+            // When host appdomains are disabled (in that case host is not shared) we need to pass the test assembly path as argument
+            // so that the test host can create one appdomain on startup (Main method) and set appbase.
             argumentsString += " --testsourcepath " + sources.FirstOrDefault()?.AddDoubleQuote();
         }
 
@@ -379,7 +379,13 @@ public void Initialize(IMessageLogger? logger, string runsettingsXml)
         _targetFramework = runConfiguration.TargetFramework;
         _testHostProcess = null;
 
-        Shared = !runConfiguration.DisableAppDomain;
+        _disableAppDomain = runConfiguration.DisableAppDomain;
+        // If appdomains are disabled the host cannot be shared, because sharing means loading multiple assemblies
+        // into the same process, and without appdomains we cannot safely do that.
+        //
+        // The OPPOSITE is not true though, disabling testhost sharing does not mean that we should not load the
+        // dll into a separate appdomain in the host. It just means that we wish to run each dll in separate exe.
+        Shared = !_disableAppDomain && !runConfiguration.DisableSharedTestHost;
         _hostExitedEventRaised = false;
 
         IsInitialized = true;
diff --git a/test/Microsoft.TestPlatform.Acceptance.IntegrationTests/DifferentTestFrameworkSimpleTests.cs b/test/Microsoft.TestPlatform.Acceptance.IntegrationTests/DifferentTestFrameworkSimpleTests.cs
index 0ab5326a1f..cde8909ee8 100644
--- a/test/Microsoft.TestPlatform.Acceptance.IntegrationTests/DifferentTestFrameworkSimpleTests.cs
+++ b/test/Microsoft.TestPlatform.Acceptance.IntegrationTests/DifferentTestFrameworkSimpleTests.cs
@@ -163,7 +163,7 @@ public void NUnitRunAllTestExecution(RunnerInfo runnerInfo)
 
         var arguments = PrepareArguments(
             GetAssetFullPath("NUTestProject.dll"),
-            GetTestAdapterPath(UnitTestFramework.NUnit),
+            null, // GetTestAdapterPath(UnitTestFramework.NUnit),
             string.Empty, FrameworkArgValue,
             runnerInfo.InIsolationValue, TempDirectory.Path);
         InvokeVsTest(arguments);
diff --git a/test/Microsoft.TestPlatform.TestHostProvider.UnitTests/Hosting/DefaultTestHostManagerTests.cs b/test/Microsoft.TestPlatform.TestHostProvider.UnitTests/Hosting/DefaultTestHostManagerTests.cs
index c38169246a..9b36182524 100644
--- a/test/Microsoft.TestPlatform.TestHostProvider.UnitTests/Hosting/DefaultTestHostManagerTests.cs
+++ b/test/Microsoft.TestPlatform.TestHostProvider.UnitTests/Hosting/DefaultTestHostManagerTests.cs
@@ -394,6 +394,20 @@ public void PropertiesShouldReturnEmptyDictionary()
         Assert.AreEqual(0, _testHostManager.Properties.Count);
     }
 
+    [TestMethod]
+    public void DefaultTestHostManagerShouldNotBeSharedWhenOptedIn()
+    {
+        _testHostManager.Initialize(_mockMessageLogger.Object, $"""
+            <?xml version="1.0" encoding="utf-8"?>
+            <RunSettings>
+            <RunConfiguration>
+                <DisableSharedTestHost>{true}</DisableSharedTestHost>
+            </RunConfiguration>
+            </RunSettings>
+            """);
+        Assert.IsFalse(_testHostManager.Shared);
+    }
+
     [TestMethod]
     public void DefaultTestHostManagerShouldBeShared()
     {