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Update Information for New Centers page
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adamjtaylor authored Nov 11, 2024
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Expand Up @@ -9,9 +9,9 @@ Welcome to the Human Tumor Atlas Network! Please see the [Onboarding Checklist](
## General Information
The [Goverance and Policy page](../addtnl_info/governance.md) of this manual provides documentation and applicable policies detailing the requirements for publications, data sharing, and data use.

All HTAN centers must have an executed Human Tumor Atlas Network DMSA (Internal Data and Materials Sharing Agreement) [(HTAN DMSA)](https://docs.google.com/document/d/1RPFm9MBJv8DjZmYZyIv0jbjtNJ8fnwGjYDjlK4lL4nc/edit) with Sage Bionetworks prior to contributing data to the HTAN Data Coordinating Center [(DCC)](https://humantumoratlas.org/htan-dcc). See also [HTAN Checklist for Acceptance of Data](../data_submission/checklist.html). Sean Hanlon from the NCI will be reaching out to new Centers to coordinate collection of DMSA signatures.
All HTAN Institutions must have an executed Human Tumor Atlas Network DMSA (Internal Data and Materials Sharing Agreement) [(HTAN DMSA)](https://docs.google.com/document/d/1RPFm9MBJv8DjZmYZyIv0jbjtNJ8fnwGjYDjlK4lL4nc/edit) with Sage Bionetworks prior to contributing data to the HTAN Data Coordinating Center [(DCC)](https://humantumoratlas.org/htan-dcc). See also [HTAN Checklist for Acceptance of Data](../data_submission/checklist.html). Sean Hanlon from the NCI will be reaching out to new Institutions to coordinate collection of DMSA signatures.

HTAN centers are assigned a [data liaison](../data_submission/Data_Liaisons.md) from the [(DCC)](https://humantumoratlas.org/htan-dcc). Trans-Network Projects (TNPs) are also assigned liaisons. Your liaison will help guide you through setting up a new atlas or project, [creating HTAN identifiers](../data_submission/creating_ids.md), and [submitting metadata and data files](../data_submission/clin_biospec_assay/). Please keep your liaison informed of publications timelines and new data submissions.
HTAN Centers are assigned a [data liaison](../data_submission/Data_Liaisons.md) from the [(DCC)](https://humantumoratlas.org/htan-dcc). Trans-Network Projects (TNPs) are also assigned liaisons. Your liaison will help guide you through onboarding to work with the DCC, [creating HTAN identifiers](../data_submission/creating_ids.md), and [submitting metadata and data files](../data_submission/clin_biospec_assay/). Please keep your DCC Data Liaison informed of publications timelines and new data submissions.

Please see the appropriate page of this manual for additional details about HTAN center responsibilities for [data de-identification](../data_submission/data_deidentification/), including submitting a data de-identification plan, and specific instructions regarding how to submit data. Clinical, biospecimen, and assay data submitted to the DCC are distributed to repositories based on access levels. Information regarding how data are accessed by external users is described more in [other parts of this manual](../overview/data_levels.md).

Expand All @@ -32,28 +32,29 @@ Step 2
Step 3
: Sign the Internal Data and Materials Sharing Agreement ([HTAN DMSA](https://docs.google.com/document/d/1RPFm9MBJv8DjZmYZyIv0jbjtNJ8fnwGjYDjlK4lL4nc/edit)).

> Sean Hanlon from the NCI will be reaching out to new Centers to coordinate collection of DMSA signatures. Please contact the [HTAN Help Desk](https://sagebionetworks.jira.com/servicedesk/customer/portal/1) with any DMSA-related questions and the Sage Bionetworks governance team will be available to assist you or your institution’s representatives.
> Sean Hanlon from the NCI will be reaching out to new Institutions to coordinate collection of DMSA signatures. Your DCC Data Liason will be able to direct you to Lisa Pasquale, Privacy and Data Protection Analyst at Sage Bionetworks who will be avaliable to assist you amd your institutions' representatives with DMSA-related questions.
Step 4
: Review the [HTAN Checklist for Acceptance of Data](../data_submission/checklist.md).

Step 5
: Review your Center’s responsibilities for [Data De-identification](https://docs.humantumoratlas.org/data_submission/data_deidentification/).
: Review your Center’s responsibilities for [Data De-identification](https://docs.humantumoratlas.org/data_submission/data_deidentification/).
> Please make sure to have a discussion with your data liason on this topic.
Step 6
: Instruct all Center members who will need to contribute or view data to create a [Synapse account](https://accounts.synapse.org/register1?appId=synapse.org).
: Instruct all indviduals who will need to contribute or view data to create a [Synapse account](https://accounts.synapse.org/register1?appId=synapse.org).

> Center Data Wranglers and any of a Center’s member(s) who will be submitting data must also become [Synapse Certified Users](https://www.synapse.org/#!Quiz:Certification). Certified Users have access to full Synapse functionality, including the ability to upload files and tables as well as create folders. To become certified, take a [short quiz](https://www.synapse.org/#!Quiz:Certification) about the [“Synapse Commons Data Use Procedure”](https://s3.amazonaws.com/static.synapse.org/governance/SynapseCommonsDataUseProcedure.pdf?v=4). This activity ensures that you understand the rules and policies that govern data sharing on Synapse. The quiz is 15 questions and should take approximately 15-20 minutes to complete. If you have any issues becoming a Synapse Certified User please contact the [HTAN Help Desk](https://sagebionetworks.jira.com/servicedesk/customer/portal/1).
> Center Data Wranglers and any of a Center’s member(s) who will be submitting data must also become [Synapse Certified Users](https://www.synapse.org/#!Quiz:Certification). Certified Users have access to full Synapse functionality, including the ability to upload files and tables as well as create folders. To become Certified, take a [short quiz](https://www.synapse.org/#!Quiz:Certification) about the [“Synapse Commons Data Use Procedure”](https://s3.amazonaws.com/static.synapse.org/governance/SynapseCommonsDataUseProcedure.pdf?v=4). This activity ensures that you understand the rules and policies that govern data sharing on Synapse. The quiz is 15 questions and should take approximately 15-20 minutes to complete. If you have any issues becoming a Synapse Certified User please contact the [HTAN Help Desk](https://sagebionetworks.jira.com/servicedesk/customer/portal/1).
Step 7
: Once each Center member has created a Synapse account, please complete the [HTAN Master Contact Form](https://airtable.com/apptQ3yP7le2ZvLjH/pag4Zop9o7mUuLPIm/form) for that member.
: Submit Center Personnel Details

> This form may only be submitted by the Member PI or Member Administrator to add a new contact with which they are affiliated. If a new contact is associated with multiple Centers or Atlases, a separate form must be submitted for each affiliation.
> The DCC will soon send you a form to submit the names, contact details, and HTAN roles of each individual in your Center. This form may only be submitted by the Center PI or Center Administrator to add an individual with which they are affiliated. If an individual is associated with multiple Centers or Atlases, a separate form must be submitted for each affiliation by that Center’s PI or Center Administrator.
Step 8
: Attend [DCC Information Sessions](#coming-soon-dcc-information-sessions)

> Once all atlases have been on-boarded, the DCC will organize a series of information sessions. All Center Data Wranglers and data submitters will be required to attend information sessions. For those unable to attend, the event will be recorded and posted to the Synapse wiki.
> Once all Centers have been on-boarded, the DCC will organize a series of information sessions. All Center Data Wranglers and data submitters will be required to attend information sessions. For those unable to attend, the event will be recorded and posted to the Synapse wiki.

## Coming Soon!: DCC Information Sessions
Expand All @@ -62,7 +63,7 @@ The following DCC Information Sessions are being planned.

|Session | Topics |
|--------|:-------|
|1| Getting Started: HTAN Identifiers, Basic Demographics, Biospecimens, and the HTAN Data Curator App|
|1| Getting Started: HTAN Identifiers, Basic Demographics, Biospecimens, uploading data to Synapse |
|2| Deeper Dive on Clinical Data, including how to encode longitudinal clinical data |
|3| Submitting Assay Data: Organizing Synapse Projects and Transferring Data |
|4| Submitting Assay Data: Single Cell Sequencing Data |
Expand All @@ -76,9 +77,5 @@ To prepare for the first information meeting, all Atlas Wranglers and data submi

- [ ] Review the **Biospecimen data model**. Biospecimen data is required, and is usually the second metadata file submitted to the DCC. For details, go to the [Biospecimen Data Model](https://data.humantumoratlas.org/standard/biospecimen), scroll to the Manifest tab, and select Biospecimens. You can also see an [example biospecimen file](https://www.synapse.org/Synapse:syn39256250) from Phase 1 of HTAN.

- [ ] Familiarize yourself with the [Data Curator App](https://dca.app.sagebionetworks.org/). Try selecting your Project and selecting 1) Clinical Demographics and 2) Biospecimens. This will generate sample manifests that you can subsequently upload via the Data Curator app. Note that you will not have access to the “HTAN Phase 2 All Projects” section of the DCA until your Data Liaison has authorized your Synapse user name.





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