DESCRIPTION

Package: nlmixr2extra
Title: Nonlinear Mixed Effects Models in Population PK/PD, Extra Support
    Functions
Version: 3.0.1.9000
Authors@R: c(
    person("Matthew", "Fidler", email="matthew.fidler@gmail.com", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0001-8538-6691")),
    person("Vipul", "Mann",email="vm2583@columbia.edu", role = "aut"),
    person("Vishal", "Sarsani", email="vsarsani@umass.edu", comment=c(ORCID = "0000-0002-9272-3438"), role="aut"),
    person("Christian", "Bartels", email="christian.bartels@novartis.com", role="ctb"),
    person("Bill", "Denney", email="wdenney@humanpredictions.com", role="aut", comment=c(ORCID="0000-0002-5759-428X"))
  )
Maintainer: Matthew Fidler <matthew.fidler@gmail.com>
Description: Fit and compare nonlinear mixed-effects models in
    differential equations with flexible dosing information commonly seen
    in pharmacokinetics and pharmacodynamics (Almquist, Leander, and
    Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation
    solving is by compiled C code provided in the 'rxode2' package (Wang,
    Hallow, and James 2015 <doi:10.1002/psp4.12052>). This package is for
    support functions like preconditioned fits
    <doi:10.1208/s12248-016-9866-5>, boostrap and stepwise covariate
    selection.
Depends:
    R (>= 4.0)
License: GPL (>= 3)
URL: https://nlmixr2.github.io/nlmixr2extra/,
    https://github.com/nlmixr2/nlmixr2extra/
BugReports: https://github.com/nlmixr2/nlmixr2extra/issues/
Imports:
    checkmate,
    cli (>= 3.4.0),
    crayon,
    data.table,
    digest,
    dplyr,
    ggplot2,
    ggtext,
    knitr,
    lotri,
    methods,
    nlme,
    nlmixr2est (>= 2.1.1),
    Rcpp,
    rxode2 (>= 2.0.10),
    stats,
    symengine,
    utils
Suggests:
    brms,
    nlmixr2data,
    testthat (>= 3.0.0),
    withr,
    devtools
LinkingTo:
    Rcpp,
    RcppArmadillo
Biarch: true
Config/testthat/edition: 3
Encoding: UTF-8
NeedsCompilation: yes
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
LazyData: true