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Cross-sectional study that analyzed retrospective data from pregnant and postpartum women diagnosed with Severe Acute Respiratory Syndrome (SARS) between January 2016 and November 2021.

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Unveiling the Hidden Burden of COVID-19 in Brazil's obstetric population with Severe Acute Respiratory Syndrome: a machine learning model

This cross-sectional study analyzed retrospective data of pregnant and postpartum women diagnosed with Severe Acute Respiratory Syndrome (SARS) between January 2016 and November 2021. Patients were divided into two groups (COVID-19 and non-COVID-19) for comparative analysis, and a XGBoost predictive model was constructed to classify cases without a defined causative agent. The results suggest that the number of COVID-19 cases and deaths in the obstetric population was much higher than documented by authorities, indicating a significant impact on the maternal mortality ratio during this period.

Funding: Bill & Melinda Gates Foundation, CNPq and FAPES.


Data

SINASC - 01.data/sinasc/

SIVEP-Gripe - 01.data/sivep-gripe/

Script

Data processing, descriptive analysis, modeling and interpretability - 02.script/

Results

Tables - 03.results/tabs/

Figures - 03.results/figs/

Supplementary material - 03.results/supplementary/

Software

R, version 4.3.3, under IDE RStudio

Operating System

macOS Sonoma 14.5, with Processor M3 Max 14-core and 36GB RAM

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Cross-sectional study that analyzed retrospective data from pregnant and postpartum women diagnosed with Severe Acute Respiratory Syndrome (SARS) between January 2016 and November 2021.

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