diff --git a/.github/workflows/deployment.yaml b/.github/workflows/deployment.yaml
new file mode 100644
index 00000000..74529b1b
--- /dev/null
+++ b/.github/workflows/deployment.yaml
@@ -0,0 +1,77 @@
+name: Deployment tests
+
+on:
+  schedule:
+    - cron: "10 */12 * * *"
+  workflow_dispatch:
+defaults:
+  run:
+    shell: bash -l {0}
+
+jobs:
+  test:
+
+    name: ${{ matrix.os }}, 🐍=${{ matrix.python-version }}, 👁️=${{ matrix.openeye }}, ∫=${{ matrix.integration }}
+    runs-on: ${{ matrix.os }}
+
+    strategy:
+      fail-fast: false
+      matrix:
+        os: [ubuntu-latest, macos-latest]
+        python-version: ["3.11"]
+        openeye: [true, false]
+        integration: [true]
+
+    env:
+      OE_LICENSE: ${{ github.workspace }}/oe_license.txt
+
+    steps:
+      - uses: actions/checkout@v4
+
+      - name: Install latest release from conda with OpenEye Toolkits
+        if: ${{ matrix.openeye == true }}
+        uses: mamba-org/setup-micromamba@v2
+        with:
+          environment-file: devtools/conda-envs/deployment_openeye.yaml
+          create-args: >-
+            python=${{ matrix.python-version }}
+
+      - name: Install latest release from conda without OpenEye Toolkits
+        if: ${{ matrix.openeye == false }}
+        uses: mamba-org/setup-micromamba@v2
+        with:
+          environment-file: devtools/conda-envs/deployment.yaml
+          create-args: >-
+            python=${{ matrix.python-version }}
+
+      - name: License OpenEye
+        if: ${{ matrix.openeye == true }}
+        run: |
+          echo "${SECRET_OE_LICENSE}" > ${OE_LICENSE}
+          python -c "from openeye import oechem; assert oechem.OEChemIsLicensed()"
+        env:
+          SECRET_OE_LICENSE: ${{ secrets.OE_LICENSE }}
+
+      - name: Checkout most recent tag
+        id: vars
+        run: |
+          echo "PULL_REQUEST_HEAD=$(git log -1 --format=%H)" >> $GITHUB_OUTPUT
+
+          git fetch --all
+          git checkout $(git describe --tags $(git rev-list --tags --max-count=1))
+
+      - name: Run tests
+        run: |
+          python -m pytest --durations=0 openff/bespokefit/_tests
+
+      - name: Run Integration Tests
+        if: ${{ matrix.integration == true }}
+        run: |
+          openff-bespoke executor run --smiles                 'CC'               \
+                                      --workflow               'default'          \
+                                      --default-qc-spec        xtb gfn2xtb none   \
+                                      --target-torsion         '[C:1]-[C:2]'
+
+      - name: Go back to pull request HEAD
+        # setup-micromamba needs the environment file to exist, which it might not on the most recent tag
+        run: git checkout ${{ steps.vars.outputs.PULL_REQUEST_HEAD }}
diff --git a/devtools/conda-envs/deployment.yaml b/devtools/conda-envs/deployment.yaml
new file mode 100644
index 00000000..10ef4851
--- /dev/null
+++ b/devtools/conda-envs/deployment.yaml
@@ -0,0 +1,12 @@
+name: latest-deployment
+channels:
+  - conda-forge
+dependencies:
+  - openff-bespokefit
+  - ambertools
+  - xtb-python
+  - pytest
+  - pytest-cov
+  - pytest-asyncio
+  - pytest-celery
+  - requests-mock
diff --git a/devtools/conda-envs/deployment_openeye.yaml b/devtools/conda-envs/deployment_openeye.yaml
new file mode 100644
index 00000000..a282e73b
--- /dev/null
+++ b/devtools/conda-envs/deployment_openeye.yaml
@@ -0,0 +1,13 @@
+name: latest-deployment-openeye
+channels:
+  - conda-forge
+  - openeye
+dependencies:
+  - openff-bespokefit
+  - openeye-toolkits
+  - xtb-python
+  - pytest
+  - pytest-cov
+  - pytest-asyncio
+  - pytest-celery
+  - requests-mock
diff --git a/devtools/conda-envs/docs-env.yaml b/devtools/conda-envs/docs-env.yaml
index c51b37e9..49e43239 100644
--- a/devtools/conda-envs/docs-env.yaml
+++ b/devtools/conda-envs/docs-env.yaml
@@ -18,8 +18,7 @@ dependencies:
   - click-option-group
   - rdkit =2024.03.5
   - openff-utilities
-  - openff-toolkit-base =0.15
-  - openff-interchange  # only needed because openff-toolkit-base
+  - openff-toolkit >=0.15
   - openff-forcefields >=2024.04.0
   - openff-qcsubmit >=0.50
   - openmm >=7.6.0
diff --git a/devtools/conda-envs/no_openeye.yaml b/devtools/conda-envs/no_openeye.yaml
index ab97952d..7369e46f 100644
--- a/devtools/conda-envs/no_openeye.yaml
+++ b/devtools/conda-envs/no_openeye.yaml
@@ -22,7 +22,6 @@ dependencies:
   - ambertools >=22
   - openff-utilities
   - openff-toolkit >=0.15
-  - openff-interchange  # only needed because openff-toolkit-base
   - openff-forcefields >=2024.04.0
   - openff-qcsubmit >=0.50
   - openmm >=7.6.0
diff --git a/devtools/conda-envs/test-env.yaml b/devtools/conda-envs/test-env.yaml
index 53d9b74a..4ade6fd4 100644
--- a/devtools/conda-envs/test-env.yaml
+++ b/devtools/conda-envs/test-env.yaml
@@ -22,7 +22,6 @@ dependencies:
   - rdkit =2024.03.5
   - openff-utilities
   - openff-toolkit >=0.15
-  - openff-interchange  # only needed because openff-toolkit-base
   - openff-forcefields >=2024.04.0
   - openff-units
   - openff-qcsubmit >=0.50
diff --git a/docs/releasehistory.md b/docs/releasehistory.md
index c6783249..e5090772 100644
--- a/docs/releasehistory.md
+++ b/docs/releasehistory.md
@@ -8,7 +8,12 @@ Releases follow the ``major.minor.micro`` scheme recommended by
 * `micro` increments represent bugfix releases or improvements in documentation
 
 <!-- ## Since last release -->
-## Current Development
+## Current development
+
+### Tests updated
+* [#207] - Adds deployment tests [@mattwthompson @jthorton @Yoshanuikabundi]
+
+## 0.4.1 / 07-11-2024
 ### Bug fixes
 * [#370] - Check that the `extras` field on QCArchive records is not `None` before accessing it to avoid crashes [@ntBre]