README.md

Recombination between heterologous human acrocentric chromosomes

Citation

Guarracino et al., 2023. Recombination between heterologous human acrocentric chromosomes, Nature, https://doi.org/10.1038/s41586-023-05976-y

Workflows

• Data and tools preparation

• Chromosome community detection

• Pangenome graph untangling:

  • Acrocentric community
  • Sex community

• Entropy and concordance computation

• Linkage Disequilibrium