diff --git a/src/pdm/cli/commands/fix/__init__.py b/src/pdm/cli/commands/fix/__init__.py
index 3f86cc7472..7dfa8e1f51 100644
--- a/src/pdm/cli/commands/fix/__init__.py
+++ b/src/pdm/cli/commands/fix/__init__.py
@@ -3,7 +3,7 @@
 import argparse
 
 from pdm.cli.commands.base import BaseCommand
-from pdm.cli.commands.fix.fixers import BaseFixer, PackageTypeFixer, ProjectConfigFixer
+from pdm.cli.commands.fix.fixers import BaseFixer, LockStrategyFixer, PackageTypeFixer, ProjectConfigFixer
 from pdm.exceptions import PdmUsageError
 from pdm.project import Project
 from pdm.termui import Emoji
@@ -49,7 +49,7 @@ def check_problems(project: Project, strict: bool = True) -> None:
     @staticmethod
     def get_fixers(project: Project) -> list[BaseFixer]:
         """Return a list of fixers to check, the order matters"""
-        return [ProjectConfigFixer(project), PackageTypeFixer(project)]
+        return [ProjectConfigFixer(project), PackageTypeFixer(project), LockStrategyFixer(project)]
 
     def handle(self, project: Project, options: argparse.Namespace) -> None:
         if options.dry_run:
diff --git a/src/pdm/cli/commands/fix/fixers.py b/src/pdm/cli/commands/fix/fixers.py
index 0c853844ad..46bcd87126 100644
--- a/src/pdm/cli/commands/fix/fixers.py
+++ b/src/pdm/cli/commands/fix/fixers.py
@@ -2,7 +2,9 @@
 import re
 
 from pdm.project import Config, Project
+from pdm.project.lockfile import FLAG_CROSS_PLATFORM
 from pdm.termui import Verbosity
+from pdm.utils import parse_version
 
 
 class BaseFixer(abc.ABC):
@@ -97,3 +99,22 @@ def fix(self) -> None:
 
         # Write the updated settings back to the project
         self.project.pyproject.write(False)
+
+
+class LockStrategyFixer(BaseFixer):
+    identifier = "deprecated-cross-platform"
+
+    def get_message(self) -> str:
+        return "Lock strategy [success]`cross_platform`[/] has been deprecated in favor of lock targets."
+
+    def check(self) -> bool:
+        lockfile_version = self.project.lockfile.file_version
+        if not lockfile_version or parse_version(lockfile_version) < parse_version("4.5.0"):
+            return False
+        return FLAG_CROSS_PLATFORM in self.project.lockfile.strategy
+
+    def fix(self) -> None:
+        strategies = self.project.lockfile.strategy - {FLAG_CROSS_PLATFORM}
+        self.project.lockfile._data["metadata"]["strategy"] = sorted(strategies)
+        self.project.lockfile.write(False)
+        self.log("Lock strategy [success]`cross_platform` has been removed.", verbosity=Verbosity.DETAIL)