diff --git a/conda/environments/all_cuda-118_arch-x86_64.yaml b/conda/environments/all_cuda-118_arch-x86_64.yaml
index 554fa9416..ffde5c912 100644
--- a/conda/environments/all_cuda-118_arch-x86_64.yaml
+++ b/conda/environments/all_cuda-118_arch-x86_64.yaml
@@ -10,13 +10,18 @@ dependencies:
 - c-compiler
 - click
 - cmake>=3.23.1,!=3.25.0
-- cudatoolkit=11.8
+- cuda-version=11.8
+- cudatoolkit
 - cupy >=12.0.0
 - cxx-compiler
 - gcc_linux-64=11.*
 - imagecodecs>=2021.6.8
 - ipython
 - jbig
+- libcufile-dev=1.4.0.31
+- libcufile=1.4.0.31
+- libnvjpeg-dev=11.6.0.55
+- libnvjpeg=11.6.0.55
 - libwebp-base
 - nbsphinx
 - ninja
diff --git a/conda/environments/all_cuda-120_arch-x86_64.yaml b/conda/environments/all_cuda-120_arch-x86_64.yaml
new file mode 100644
index 000000000..ae0339e39
--- /dev/null
+++ b/conda/environments/all_cuda-120_arch-x86_64.yaml
@@ -0,0 +1,52 @@
+# This file is generated by `rapids-dependency-file-generator`.
+# To make changes, edit ../../dependencies.yaml and run `rapids-dependency-file-generator`.
+channels:
+- rapidsai
+- rapidsai-nightly
+- conda-forge
+- nvidia
+dependencies:
+- GPUtil>=1.4.0
+- c-compiler
+- click
+- cmake>=3.23.1,!=3.25.0
+- cuda-cudart-dev
+- cuda-nvcc
+- cuda-version=12.0
+- cupy >=12.0.0
+- cxx-compiler
+- gcc_linux-64=11.*
+- imagecodecs>=2021.6.8
+- ipython
+- jbig
+- libcufile-dev
+- libnvjpeg-dev
+- libnvjpeg-static
+- libwebp-base
+- nbsphinx
+- ninja
+- numpy >=1.21.3
+- numpydoc
+- openslide-python>=1.1.2
+- pip
+- pre-commit
+- psutil>=5.8.0
+- pydata-sphinx-theme
+- pytest-cov>=2.12.1
+- pytest-lazy-fixture>=0.6.3
+- pytest-xdist
+- pytest>=6.2.4
+- python>=3.8,<3.11
+- recommonmark
+- scikit-image >=0.19.0,<0.22.0a0
+- scipy
+- sphinx<6
+- sysroot_linux-64==2.17
+- tifffile>=2022.7.28
+- xz
+- yasm
+- zlib
+- zstd
+- pip:
+  - opencv-python-headless>=4.6
+name: all_cuda-120_arch-x86_64
diff --git a/conda/recipes/cucim/conda_build_config.yaml b/conda/recipes/cucim/conda_build_config.yaml
index ccc49851a..fb04ce5c8 100644
--- a/conda/recipes/cucim/conda_build_config.yaml
+++ b/conda/recipes/cucim/conda_build_config.yaml
@@ -4,5 +4,11 @@ c_compiler_version:
 cxx_compiler_version:
   - 11
 
+cuda_compiler:
+  - cuda-nvcc
+
+cuda11_compiler:
+  - nvcc
+
 sysroot_version:
   - "2.17"
diff --git a/conda/recipes/cucim/meta.yaml b/conda/recipes/cucim/meta.yaml
index 3947862b8..653e1bc6d 100644
--- a/conda/recipes/cucim/meta.yaml
+++ b/conda/recipes/cucim/meta.yaml
@@ -1,12 +1,12 @@
 # Copyright (c) 2021-2023, NVIDIA CORPORATION.
 
 {% set version = environ.get('GIT_DESCRIBE_TAG', '0.0.0.dev').lstrip('v') %}
-{% set minor_version = version.split('.')[0] + '.' + version.split('.')[2] %}
 {% set py_version = environ['CONDA_PY'] %}
 {% set cuda_version = '.'.join(environ['RAPIDS_CUDA_VERSION'].split('.')[:2]) %}
 {% set cuda_major = cuda_version.split('.')[0] %}
 {% set date_string = environ['RAPIDS_DATE_STRING'] %}
 
+
 package:
   name: cucim
   version: {{ version }}
@@ -38,13 +38,19 @@ requirements:
   build:
     - {{ compiler("c") }}
     - {{ compiler("cxx") }}
+    {% if cuda_major == "11" %}
+    - {{ compiler('cuda11') }} ={{ cuda_version }}
+    {% else %}
+    - {{ compiler('cuda') }}
+    {% endif %}
+    - cuda-version ={{ cuda_version }}
     - cmake >=3.23.1,!=3.25.0
     - make
     - ninja
     - sysroot_{{ target_platform }} {{ sysroot_version }}
   host:
     - click
-    - cudatoolkit ={{ cuda_version }}
+    - cuda-version ={{ cuda_version }}
     - cupy >=12.0.0
     - libcucim ={{ version }}
     - numpy 1.21
@@ -52,7 +58,7 @@ requirements:
     - scikit-image >=0.19.0,<0.22.0a0
     - scipy
   run:
-    - {{ pin_compatible('cudatoolkit', max_pin='x', min_pin='x') }}
+    - {{ pin_compatible('cuda-version', max_pin='x', min_pin='x') }}
     - {{ pin_compatible('numpy') }}
     - click
     - cupy >=12.0.0
@@ -64,7 +70,7 @@ requirements:
 
 tests:
   requirements:
-    - cudatoolkit ={{ cuda_version }}
+    - cuda-version ={{ cuda_version }}
   imports:
     - cucim
 
diff --git a/conda/recipes/libcucim/build.sh b/conda/recipes/libcucim/build.sh
index 7d21aebe3..d9da2e18d 100644
--- a/conda/recipes/libcucim/build.sh
+++ b/conda/recipes/libcucim/build.sh
@@ -4,7 +4,6 @@ CUCIM_BUILD_TYPE=${CUCIM_BUILD_TYPE:-release}
 
 echo "CC          : ${CC}"
 echo "CXX         : ${CXX}"
-echo "CUDA        : ${CUDA}"
 
 # CUDA needs to include $PREFIX/include as system include path
 export CUDAFLAGS="-isystem $BUILD_PREFIX/include -isystem $PREFIX/include "
diff --git a/conda/recipes/libcucim/conda_build_config.yaml b/conda/recipes/libcucim/conda_build_config.yaml
index 6c2368ed8..4f3ea2a0b 100644
--- a/conda/recipes/libcucim/conda_build_config.yaml
+++ b/conda/recipes/libcucim/conda_build_config.yaml
@@ -4,8 +4,27 @@ c_compiler_version:
 cxx_compiler_version:
   - 11
 
+cuda_compiler:
+  - cuda-nvcc
+
+cuda11_compiler:
+  - nvcc
+
 sysroot_version:
   - "2.17"
 
 libwebp_base_version:
   - "<1.3a0"
+
+# The CTK libraries below are missing from the conda-forge::cudatoolkit package
+# for CUDA 11. The "*_host_*" version specifiers correspond to `11.8` packages
+# and the "*_run_*" version specifiers correspond to `11.x` packages.
+
+cuda11_libcufile_host_version:
+  - "1.4.0.31"
+
+cuda11_libcufile_run_version:
+  - ">=1.0.0.82,<=1.4.0.31"
+
+cuda11_libnvjpeg_host_version:
+  - "11.6.0.55"
diff --git a/conda/recipes/libcucim/meta.yaml b/conda/recipes/libcucim/meta.yaml
index 3e610efb6..c372f822b 100644
--- a/conda/recipes/libcucim/meta.yaml
+++ b/conda/recipes/libcucim/meta.yaml
@@ -1,11 +1,11 @@
 # Copyright (c) 2021-2023, NVIDIA CORPORATION.
 
 {% set version = environ.get('GIT_DESCRIBE_TAG', '0.0.0.dev').lstrip('v') %}
-{% set minor_version = version.split('.')[0] + '.' + version.split('.')[1] %}
 {% set cuda_version = '.'.join(environ['RAPIDS_CUDA_VERSION'].split('.')[:2]) %}
 {% set cuda_major = cuda_version.split('.')[0] %}
 {% set date_string = environ['RAPIDS_DATE_STRING'] %}
 
+
 package:
   name: libcucim
   version: {{ version }}
@@ -39,6 +39,12 @@ requirements:
   build:
     - {{ compiler("c") }}
     - {{ compiler("cxx") }}
+    {% if cuda_major == "11" %}
+    - {{ compiler('cuda11') }} ={{ cuda_version }}
+    {% else %}
+    - {{ compiler('cuda') }}
+    {% endif %}
+    - cuda-version ={{ cuda_version }}
     - binutils
     - cmake >=3.23.1,!=3.25.0
     - make
@@ -46,15 +52,30 @@ requirements:
     - sysroot_{{ target_platform }} {{ sysroot_version }}
     - yasm # [x86_64]
   host:
-    - cudatoolkit ={{ cuda_version }}
+    - cuda-version ={{ cuda_version }}
+    {% if cuda_major == "11" %}
+    - libcufile {{ cuda11_libcufile_host_version }}         # [linux64]
+    - libcufile-dev {{ cuda11_libcufile_host_version }}     # [linux64]
+    - libnvjpeg {{ cuda11_libnvjpeg_host_version }}
+    - libnvjpeg-dev {{ cuda11_libnvjpeg_host_version }}
+    {% else %}
+    - libcufile-dev     # [linux64]
+    - libnvjpeg-dev
+    - libnvjpeg-static
+    {% endif %}
     - jbig
     - libwebp-base {{ libwebp_base_version }}
+    - nvtx-c >=3.1.0
     - openslide
     - xz
     - zlib
     - zstd
   run:
-    - {{ pin_compatible('cudatoolkit', max_pin='x', min_pin='x') }}
+    - {{ pin_compatible('cuda-version', max_pin='x', min_pin='x') }}
+    {% if cuda_major == "11" %}
+    - cudatoolkit
+    - libcufile {{ cuda11_libcufile_run_version }}      # [linux64]
+    {% endif %}
     - {{ pin_compatible('libwebp-base', max_pin='x.x') }}
     - jbig
     # - openslide # skipping here but benchmark binary would need openslide library
diff --git a/dependencies.yaml b/dependencies.yaml
index c2c429532..54a355aad 100644
--- a/dependencies.yaml
+++ b/dependencies.yaml
@@ -3,7 +3,7 @@ files:
   all:
     output: conda
     matrix:
-      cuda: ["11.8"]
+      cuda: ["11.8", "12.0"]
       arch: [x86_64]
     includes:
       - build
@@ -66,12 +66,28 @@ dependencies:
               arch: x86_64
               cuda: "11.8"
             packages:
+              - cuda-version=11.8
               - nvcc_linux-64=11.8
+              - libcufile=1.4.0.31
+              - libcufile-dev=1.4.0.31
+              - libnvjpeg=11.6.0.55
+              - libnvjpeg-dev=11.6.0.55
           - matrix:
               arch: aarch64
               cuda: "11.8"
             packages:
+              - cuda-version=11.8
               - nvcc_linux-aarch64=11.8
+              - libnvjpeg=11.6.0.55
+              - libnvjpeg-dev=11.6.0.55
+          - matrix:
+              cuda: "12.0"
+            packages:
+              - cuda-version=12.0
+              - cuda-nvcc
+              - libcufile-dev
+              - libnvjpeg-dev
+              - libnvjpeg-static
   checks:
     common:
       - output_types: [conda, requirements]
@@ -84,19 +100,30 @@ dependencies:
           - matrix:
               cuda: "11.2"
             packages:
-              - cudatoolkit=11.2
+              - cuda-version=11.2
+              - cudatoolkit
           - matrix:
               cuda: "11.4"
             packages:
-              - cudatoolkit=11.4
+              - cuda-version=11.4
+              - cudatoolkit
           - matrix:
               cuda: "11.5"
             packages:
-              - cudatoolkit=11.5
+              - cuda-version=11.5
+              - cudatoolkit
           - matrix:
               cuda: "11.8"
             packages:
-              - cudatoolkit=11.8
+              - cuda-version=11.8
+              - cudatoolkit
+          - matrix:
+              cuda: "12.0"
+            packages:
+              - cuda-version=12.0
+              - cuda-cudart-dev
+              - libnvjpeg-dev
+              - libcufile-dev
   docs:
     common:
       - output_types: [conda, requirements]
diff --git a/run b/run
index 35a2e6674..7f8ac5188 100755
--- a/run
+++ b/run
@@ -432,7 +432,26 @@ build_local() {
 
 copy_gds_files_() {
     local root_folder=${1:-${TOP}}
-    local cufile_search="${root_folder}/temp/cuda/include:${root_folder}/temp/cuda/lib64"  #"/usr/local/cuda/include:/usr/local/cuda/lib64 ${PREFIX:-}/include:${PREFIX:-}/lib ${CONDA_PREFIX:-}/include:${CONDA_PREFIX:-}/lib ${root_folder}/temp/cuda/include:${root_folder}/temp/cuda/lib64"
+    local cufile_search="${root_folder}/temp/cuda/include:${root_folder}/temp/cuda/lib64"
+    local targets_dir=""
+    if [[ "$(arch)" == "x86_64" ]]
+    then
+      targets_dir="targets/x86_64-linux"
+    elif [[ "$(arch)" == "aarch64" ]]
+    then
+      targets_dir="targets/sbsa-linux"
+    else
+      echo "Unknown architecture"
+      exit 1
+    fi
+    if [[ ! -z "${CONDA_PREFIX+x}" ]]
+    then
+      cufile_search="${CONDA_PREFIX:-}/include:${CONDA_PREFIX:-}/lib ${CONDA_PREFIX:-}/${targets_dir}/include:${CONDA_PREFIX:-}/${targets_dir}/lib ${cufile_search}"
+    fi
+    if [[ ! -z "${PREFIX+x}" ]]
+    then
+      cufile_search="${PREFIX:-}/include:${PREFIX:-}/lib ${PREFIX:-}/${targets_dir}/include:${PREFIX:-}/${targets_dir}/lib ${cufile_search}"
+    fi
     local gds_version=1.0.0
     local candidate
     local cufile_include
@@ -486,6 +505,25 @@ copy_nvjpeg_files_() {
     local root_folder=${1:-${TOP}}
     local arch_name="$(get_arch_name_)"
     local nvjpeg_search="${root_folder}/temp/cuda/include:${root_folder}/temp/cuda/lib64"
+    local targets_dir=""
+    if [[ "$(arch)" == "x86_64" ]]
+    then
+      targets_dir="targets/x86_64-linux"
+    elif [[ "$(arch)" == "aarch64" ]]
+    then
+      targets_dir="targets/sbsa-linux"
+    else
+      echo "Unknown architecture"
+      exit 1
+    fi
+    if [[ ! -z "${CONDA_PREFIX+x}" ]]
+    then
+      nvjpeg_search="${CONDA_PREFIX:-}/include:${CONDA_PREFIX:-}/lib ${CONDA_PREFIX:-}/${targets_dir}/include:${CONDA_PREFIX:-}/${targets_dir}/lib ${nvjpeg_search}"
+    fi
+    if [[ ! -z "${PREFIX+x}" ]]
+    then
+      nvjpeg_search="${PREFIX:-}/include:${PREFIX:-}/lib ${PREFIX:-}/${targets_dir}/include:${PREFIX:-}/${targets_dir}/lib ${nvjpeg_search}"
+    fi
     local cuda_version="11.6"
     local nvjpeg_version="11-6_11.6.0.55-1"
     local candidate