diff --git a/.github/workflows/starfish-prod-ci.yml b/.github/workflows/starfish-prod-ci.yml
index 22aa76dbb..13d1ae552 100644
--- a/.github/workflows/starfish-prod-ci.yml
+++ b/.github/workflows/starfish-prod-ci.yml
@@ -17,10 +17,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
@@ -41,7 +41,7 @@ jobs:
     strategy:
       matrix:
         os: ["windows-latest", "ubuntu-latest"]
-        python-version: ["3.8", "3.9", "3.10"]
+        python-version: ["3.9", "3.10", "3.11"]
       fail-fast: false
     runs-on: ${{ matrix.os }}
     steps:
@@ -71,7 +71,7 @@ jobs:
     strategy:
       matrix:
         os: ["windows-latest", "ubuntu-latest"]
-        python-version: ["3.8", "3.9", "3.10"]
+        python-version: ["3.9", "3.10", "3.11"]
       fail-fast: false
     runs-on: ${{ matrix.os }}
     steps:
@@ -164,10 +164,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
@@ -189,10 +189,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
@@ -214,10 +214,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
@@ -239,10 +239,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
@@ -264,10 +264,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
@@ -289,10 +289,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
@@ -314,10 +314,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
@@ -339,10 +339,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
@@ -364,10 +364,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setpu Python 3.8
+      - name: Setpu Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
       
       - uses: actions/cache@v2
         with:
@@ -389,10 +389,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
@@ -414,10 +414,10 @@ jobs:
     steps:
       - uses: actions/checkout@v2
 
-      - name: Setup Python 3.8
+      - name: Setup Python 3.9
         uses: actions/setup-python@v2
         with:
-          python-version: 3.8
+          python-version: 3.9
 
       - uses: actions/cache@v2
         with:
diff --git a/Makefile b/Makefile
index 02c4cbc87..d9c359659 100644
--- a/Makefile
+++ b/Makefile
@@ -12,7 +12,7 @@ DOCKER_BUILD?=1
 
 VERSION=$(shell sh -c "git describe --exact --dirty 2> /dev/null")
 # if you update this, you will need to update the version pin for the "Install Napari & Test napari (pinned)" test in .travis.yml
-PIP_VERSION=24.0
+PIP_VERSION=24.2
 
 define print_help
     @printf "    %-28s   $(2)\n" $(1)
@@ -102,7 +102,7 @@ pin-all-requirements:
 starfish/REQUIREMENTS-STRICT.txt : REQUIREMENTS.txt
 	[ ! -e .$<-env ] || exit 1
 	$(call create_venv, .$<-env)
-	.$<-env/bin/pip install --upgrade pip==$(PIP_VERSION)
+	.$<-env/bin/pip install --upgrade --no-cache-dir pip==$(PIP_VERSION) setuptools
 	.$<-env/bin/pip install -r $<
 	echo "# You should not edit this file directly.  Instead, you should edit one of the following files ($^) and run make $@" >| $@
 	.$<-env/bin/pip freeze --all | grep -v "pip==$(PIP_VERSION)" >> $@
@@ -111,7 +111,7 @@ starfish/REQUIREMENTS-STRICT.txt : REQUIREMENTS.txt
 requirements/REQUIREMENTS-%.txt : requirements/REQUIREMENTS-%.txt.in REQUIREMENTS.txt
 	[ ! -e .$<-env ] || exit 1
 	$(call create_venv, .$<-env)
-	.$<-env/bin/pip install --upgrade pip==$(PIP_VERSION)
+	.$<-env/bin/pip install --upgrade --no-cache-dir pip==$(PIP_VERSION) setuptools
 	for src in $^; do \
 		.$<-env/bin/pip install -r $$src; \
 	done
diff --git a/README.rst b/README.rst
index e77682757..07ff1d07f 100644
--- a/README.rst
+++ b/README.rst
@@ -47,7 +47,7 @@ See `spacetx-starfish.readthedocs.io <https://spacetx-starfish.readthedocs.io/en
 Installation
 ------------
 
-starfish supports python 3.8-11 and can easily be installed from PyPI:
+starfish supports python 3.9-11 and can easily be installed from PyPI:
 
 .. code-block:: bash
 
@@ -58,8 +58,8 @@ starfish supports python 3.8-11 and can easily be installed from PyPI:
 Python Version Notice
 ---------------------
 
-starfish will be dropping support for python 3.8 in the next release due to
-minimum python=3.9 version requirements in upstream dependencies.
+starfish will be dropping support for python 3.9 in future release when
+upstream dependencies will require a minimum python=3.10 version.
 
 Contributing
 ------------
diff --git a/docker/Dockerfile b/docker/Dockerfile
index 8f563fb1c..7d1b22493 100644
--- a/docker/Dockerfile
+++ b/docker/Dockerfile
@@ -36,7 +36,7 @@
 ##
 ##   $ docker run -e TEST_ISS_KEEP_DATA=true --entrypoint=pytest spacetx/starfish -vsxk TestWithIssData
 ##
-FROM python:3.8-slim-buster
+FROM python:3.9-slim-buster
 
 RUN useradd -m starfish
 USER starfish
diff --git a/docs/source/installation/index.rst b/docs/source/installation/index.rst
index e211eaaae..91f0e929d 100644
--- a/docs/source/installation/index.rst
+++ b/docs/source/installation/index.rst
@@ -3,7 +3,7 @@
 Installation
 ============
 
-Starfish supports python 3.8-11. To install the starfish package,
+Starfish supports python 3.9-11. To install the starfish package,
 first verify that your python version is compatible. You can check this by running :code:`python
 --version`.
 
@@ -12,7 +12,7 @@ The output should look similar to this:
 .. code-block:: bash
 
    $ python --version
-   Python 3.8.18
+   Python 3.9.18
 
 .. warning::
     While starfish itself should work on any operating system, some napari dependencies might not be
@@ -44,7 +44,7 @@ Conda_ users can set one up like so:
 
 .. code-block:: bash
 
-    $ conda create -n starfish "python=3.8"
+    $ conda create -n starfish "python=3.9"
     $ conda activate starfish
 
 Installing *starfish*
@@ -73,7 +73,7 @@ Installing *starfish* on Windows
 --------------------------------
 
 Windows (cmd.exe) users can install starfish in the same way. Again, we recommend using a conda or virtual
-environment with python 3.8+. Here is how you would install starfish in a virtual environment
+environment with python 3.9+. Here is how you would install starfish in a virtual environment
 created with python's ``venv`` module:
 
 .. code-block:: bat
diff --git a/examples/quick_start/plot_quick_start.py b/examples/quick_start/plot_quick_start.py
index aa8c2b028..407ce9065 100644
--- a/examples/quick_start/plot_quick_start.py
+++ b/examples/quick_start/plot_quick_start.py
@@ -13,13 +13,11 @@
 Prerequisites
 -------------
 
-* Python 3.6+ installed (Python 3.7 recommended)
+* Python 3.9+ installed (Python 3.10 recommended)
 * Some basic knowledge of scientific computing in Python_
 * :ref:`Starfish library installed <installation>`
-* seaborn_ is installed: :code:`pip install seaborn`
 
 .. _Python: https://docs.scipy.org/doc/numpy/user/quickstart.html
-.. _seaborn: https://seaborn.pydata.org/
 
 Starfish Pipeline
 -----------------
diff --git a/examples/tutorials/transforms_list.json b/examples/tutorials/transforms_list.json
index f3091fb21..107dc7145 100644
--- a/examples/tutorials/transforms_list.json
+++ b/examples/tutorials/transforms_list.json
@@ -1 +1 @@
-{"transforms_list": [[{"r": 0}, "similarity", [[1.0, -0.0, -22.926], [0.0, 1.0, 5.673], [0.0, 0.0, 1.0]]], [{"r": 1}, "similarity", [[1.0, -0.0, -22.301], [0.0, 1.0, 1.6440000000000001], [0.0, 0.0, 1.0]]], [{"r": 2}, "similarity", [[1.0, -0.0, -22.124], [0.0, 1.0, -3.278], [0.0, 0.0, 1.0]]], [{"r": 3}, "similarity", [[1.0, -0.0, -14.998], [0.0, 1.0, -4.397], [0.0, 0.0, 1.0]]]], "version": "0.0.0"}
\ No newline at end of file
+{"transforms_list": [[{"r": 0}, "similarity", [[1.0, -0.0, -22.868999481201172], [0.0, 1.0, 5.85699987411499], [0.0, 0.0, 1.0]]], [{"r": 1}, "similarity", [[1.0, -0.0, -22.13599967956543], [0.0, 1.0, 1.871999979019165], [0.0, 0.0, 1.0]]], [{"r": 2}, "similarity", [[1.0, -0.0, -21.957000732421875], [0.0, 1.0, -3.5799999237060547], [0.0, 0.0, 1.0]]], [{"r": 3}, "similarity", [[1.0, -0.0, -14.98799991607666], [0.0, 1.0, -4.414999961853027], [0.0, 0.0, 1.0]]]], "version": "0.0.0"}
\ No newline at end of file
diff --git a/requirements/REQUIREMENTS-CI.txt b/requirements/REQUIREMENTS-CI.txt
index c7b48e931..2c5905e59 100644
--- a/requirements/REQUIREMENTS-CI.txt
+++ b/requirements/REQUIREMENTS-CI.txt
@@ -1,22 +1,21 @@
 # You should not edit this file directly.  Instead, you should edit one of the following files (requirements/REQUIREMENTS-CI.txt.in) and run make requirements/REQUIREMENTS-CI.txt
-alabaster==0.7.13
+alabaster==0.7.16
 asttokens==2.4.1
 attrs==24.2.0
-Babel==2.15.0
-backcall==0.2.0
+babel==2.16.0
 backports.tarfile==1.2.0
 beautifulsoup4==4.12.3
 bleach==6.1.0
-boto3==1.34.156
-botocore==1.34.156
-certifi==2024.7.4
-cffi==1.17.0
+boto3==1.35.13
+botocore==1.35.13
+certifi==2024.8.30
+cffi==1.17.1
 charset-normalizer==3.3.2
 click==8.1.7
 commonmark==0.9.1
-contourpy==1.1.1
+contourpy==1.3.0
 coverage==7.6.1
-cryptography==43.0.0
+cryptography==43.0.1
 cycler==0.12.1
 decorator==5.1.1
 defusedxml==0.7.1
@@ -25,21 +24,21 @@ docutils==0.20.1
 entrypoints==0.4
 exceptiongroup==1.2.2
 execnet==2.1.1
-executing==2.0.1
+executing==2.1.0
 fastjsonschema==2.20.0
 flake8==7.1.1
 flake8-import-order==0.18.2
 fonttools==4.53.1
 h5py==3.11.0
-idna==3.7
-imageio==2.34.2
+idna==3.8
+imageio==2.35.1
 imagesize==1.4.1
-importlib_metadata==8.2.0
-importlib_resources==6.4.0
+importlib_metadata==8.4.0
+importlib_resources==6.4.4
 iniconfig==2.0.0
-ipython==8.12.3
+ipython==8.18.1
 jaraco.classes==3.4.0
-jaraco.context==5.3.0
+jaraco.context==6.0.1
 jaraco.functools==4.0.2
 jedi==0.19.1
 jeepney==0.8.0
@@ -51,11 +50,11 @@ jupyter_client==8.6.2
 jupyter_core==5.7.2
 jupyterlab_pygments==0.3.0
 keyring==25.3.0
-kiwisolver==1.4.5
+kiwisolver==1.4.7
 lazy_loader==0.4
 looseversion==1.3.0
-lxml==5.2.2
-lxml_html_clean==0.2.0
+lxml==5.3.0
+lxml_html_clean==0.2.2
 m2r2==0.3.3.post2
 markdown-it-py==3.0.0
 MarkupSafe==2.1.5
@@ -64,7 +63,7 @@ matplotlib-inline==0.1.7
 mccabe==0.7.0
 mdurl==0.1.2
 mistune==0.8.4
-more-itertools==10.4.0
+more-itertools==10.5.0
 mpmath==1.3.0
 mypy==1.10.1
 mypy-extensions==1.0.0
@@ -72,19 +71,17 @@ nbclient==0.10.0
 nbconvert==6.5.4
 nbencdec==0.0.10
 nbformat==5.10.4
-networkx==3.1
+networkx==3.2.1
 nh3==0.2.18
 numpy==1.24.4
-numpydoc==1.7.0
+numpydoc==1.8.0
 packaging==24.1
-pandas==2.0.3
+pandas==2.2.2
 pandocfilters==1.5.1
 parso==0.8.4
 pexpect==4.9.0
-pickleshare==0.7.5
 pillow==10.4.0
 pkginfo==1.10.0
-pkgutil_resolve_name==1.3.10
 platformdirs==4.2.2
 pluggy==1.5.0
 prompt_toolkit==3.0.47
@@ -94,16 +91,16 @@ pycodestyle==2.12.1
 pycparser==2.22
 pyflakes==3.2.0
 Pygments==2.18.0
-pyparsing==3.1.2
+pyparsing==3.1.4
 pyrsistent==0.20.0
 pytest==8.3.2
 pytest-cov==5.0.0
 pytest-xdist==3.6.1
 python-dateutil==2.9.0.post0
 pytz==2024.1
-PyWavelets==1.4.1
+PyWavelets==1.6.0
 PyYAML==6.0.2
-pyzmq==26.1.0
+pyzmq==26.2.0
 read-roi==1.6.0
 readme_renderer==43.0
 recommonmark==0.7.1
@@ -111,38 +108,38 @@ regional==1.1.2
 requests==2.32.3
 requests-toolbelt==1.0.0
 rfc3986==2.0.0
-rich==13.7.1
+rich==13.8.0
 s3transfer==0.10.2
 scikit-image==0.21.0
-scikit-learn==1.3.2
-scipy==1.10.1
+scikit-learn==1.5.1
+scipy==1.13.1
 seaborn==0.13.2
 SecretStorage==3.3.3
 semantic-version==2.10.0
-setuptools==56.0.0
+setuptools==74.1.2
 showit==1.1.4
 six==1.16.0
 slicedimage==4.1.1
 snowballstemmer==2.2.0
-soupsieve==2.5
-Sphinx==7.1.2
-sphinx-autodoc-typehints==2.0.1
+soupsieve==2.6
+Sphinx==7.4.7
+sphinx-autodoc-typehints==2.3.0
 sphinx-bootstrap-theme==0.8.1
 sphinx-gallery==0.17.1
 sphinx-rtd-theme==2.0.0
-sphinxcontrib-applehelp==1.0.4
-sphinxcontrib-devhelp==1.0.2
-sphinxcontrib-htmlhelp==2.0.1
+sphinxcontrib-applehelp==2.0.0
+sphinxcontrib-devhelp==2.0.0
+sphinxcontrib-htmlhelp==2.1.0
 sphinxcontrib-jquery==4.1
 sphinxcontrib-jsmath==1.0.1
 sphinxcontrib-programoutput==0.17
-sphinxcontrib-qthelp==1.0.3
-sphinxcontrib-serializinghtml==1.1.5
+sphinxcontrib-qthelp==2.0.0
+sphinxcontrib-serializinghtml==2.0.0
 stack-data==0.6.3
-sympy==1.13.1
+sympy==1.13.2
 tabulate==0.9.0
 threadpoolctl==3.5.0
-tifffile==2023.7.10
+tifffile==2024.8.30
 tinycss2==1.3.0
 tomli==2.0.1
 tornado==6.4.1
@@ -152,13 +149,13 @@ traitlets==5.14.3
 twine==5.1.1
 types-PyYAML==6.0.12.20240808
 types-requests==2.31.0.6
-types-setuptools==71.1.0.20240806
+types-setuptools==74.1.0.20240906
 types-urllib3==1.26.25.14
 typing_extensions==4.12.2
 tzdata==2024.1
-urllib3==1.26.19
-validators==0.33.0
+urllib3==1.26.20
+validators==0.34.0
 wcwidth==0.2.13
 webencodings==0.5.1
-xarray==2023.1.0
-zipp==3.19.2
+xarray==2023.8.0
+zipp==3.20.1
diff --git a/requirements/REQUIREMENTS-CI.txt.in b/requirements/REQUIREMENTS-CI.txt.in
index 59a5d6e77..1f8ca3fa9 100644
--- a/requirements/REQUIREMENTS-CI.txt.in
+++ b/requirements/REQUIREMENTS-CI.txt.in
@@ -6,9 +6,10 @@ flake8-import-order
 lxml_html_clean
 # pin m2r2: https://github.com/CrossNox/m2r2/issues/52
 m2r2>=0.3.3
-mypy != 0.740
+# temporarily limiting mypy as 1.11 introduces errors
+mypy<1.11
 numpydoc
-nbencdec >= 0.0.5
+nbencdec>=0.0.5
 pycodestyle
 pytest>=4.4.0
 pytest-cov>=2.5.1
diff --git a/requirements/REQUIREMENTS-JUPYTER.txt b/requirements/REQUIREMENTS-JUPYTER.txt
index 712b34197..bfa50197f 100644
--- a/requirements/REQUIREMENTS-JUPYTER.txt
+++ b/requirements/REQUIREMENTS-JUPYTER.txt
@@ -6,18 +6,17 @@ arrow==1.3.0
 asttokens==2.4.1
 async-lru==2.0.4
 attrs==24.2.0
-Babel==2.15.0
-backcall==0.2.0
+babel==2.16.0
 beautifulsoup4==4.12.3
 bleach==6.1.0
-boto3==1.34.156
-botocore==1.34.156
-certifi==2024.7.4
-cffi==1.17.0
+boto3==1.35.13
+botocore==1.35.13
+certifi==2024.8.30
+cffi==1.17.1
 charset-normalizer==3.3.2
 click==8.1.7
 comm==0.2.2
-contourpy==1.1.1
+contourpy==1.3.0
 cycler==0.12.1
 debugpy==1.8.5
 decorator==5.1.1
@@ -26,21 +25,21 @@ diskcache==5.6.3
 docutils==0.20.1
 entrypoints==0.4
 exceptiongroup==1.2.2
-executing==2.0.1
+executing==2.1.0
 fastjsonschema==2.20.0
 fonttools==4.53.1
 fqdn==1.5.1
 h11==0.14.0
 h5py==3.11.0
 httpcore==1.0.5
-httpx==0.27.0
-idna==3.7
-imageio==2.34.2
-importlib_metadata==8.2.0
-importlib_resources==6.4.0
+httpx==0.27.2
+idna==3.8
+imageio==2.35.1
+importlib_metadata==8.4.0
+importlib_resources==6.4.4
 ipykernel==6.29.5
-ipython==8.12.3
-ipywidgets==8.1.3
+ipython==8.18.1
+ipywidgets==8.1.5
 isoduration==20.11.0
 jedi==0.19.1
 Jinja2==3.1.4
@@ -49,7 +48,7 @@ joblib==1.4.2
 json5==0.9.25
 jsonpointer==3.0.0
 jsonschema==4.17.3
-jupyter==1.0.0
+jupyter==1.1.1
 jupyter-console==6.6.3
 jupyter-events==0.6.3
 jupyter-lsp==2.2.5
@@ -60,11 +59,11 @@ jupyter_server_terminals==0.5.3
 jupyterlab==4.1.6
 jupyterlab_pygments==0.3.0
 jupyterlab_server==2.24.0
-jupyterlab_widgets==3.0.11
-kiwisolver==1.4.5
+jupyterlab_widgets==3.0.13
+kiwisolver==1.4.7
 lazy_loader==0.4
 looseversion==1.3.0
-lxml==5.2.2
+lxml==5.3.0
 MarkupSafe==2.1.5
 matplotlib==3.7.5
 matplotlib-inline==0.1.7
@@ -74,19 +73,17 @@ nbclient==0.10.0
 nbconvert==6.5.4
 nbformat==5.10.4
 nest-asyncio==1.6.0
-networkx==3.1
+networkx==3.2.1
 notebook==7.1.3
 notebook_shim==0.2.4
 numpy==1.24.4
 overrides==7.7.0
 packaging==24.1
-pandas==2.0.3
+pandas==2.2.2
 pandocfilters==1.5.1
 parso==0.8.4
 pexpect==4.9.0
-pickleshare==0.7.5
 pillow==10.4.0
-pkgutil_resolve_name==1.3.10
 platformdirs==4.2.2
 prometheus_client==0.20.0
 prompt_toolkit==3.0.47
@@ -95,16 +92,14 @@ ptyprocess==0.7.0
 pure_eval==0.2.3
 pycparser==2.22
 Pygments==2.18.0
-pyparsing==3.1.2
+pyparsing==3.1.4
 pyrsistent==0.20.0
 python-dateutil==2.9.0.post0
 python-json-logger==2.0.7
 pytz==2024.1
-PyWavelets==1.4.1
+PyWavelets==1.6.0
 PyYAML==6.0.2
-pyzmq==26.1.0
-qtconsole==5.5.2
-QtPy==2.4.1
+pyzmq==26.2.0
 read-roi==1.6.0
 regional==1.1.2
 requests==2.32.3
@@ -112,38 +107,38 @@ rfc3339-validator==0.1.4
 rfc3986-validator==0.1.1
 s3transfer==0.10.2
 scikit-image==0.21.0
-scikit-learn==1.3.2
-scipy==1.10.1
+scikit-learn==1.5.1
+scipy==1.13.1
 seaborn==0.13.2
 semantic-version==2.10.0
 Send2Trash==1.8.3
-setuptools==56.0.0
+setuptools==74.1.2
 showit==1.1.4
 six==1.16.0
 slicedimage==4.1.1
 sniffio==1.3.1
-soupsieve==2.5
+soupsieve==2.6
 stack-data==0.6.3
-sympy==1.13.1
+sympy==1.13.2
 terminado==0.18.1
 threadpoolctl==3.5.0
-tifffile==2023.7.10
+tifffile==2024.8.30
 tinycss2==1.3.0
 tomli==2.0.1
 tornado==6.4.1
 tqdm==4.66.5
 trackpy==0.6.4
 traitlets==5.14.3
-types-python-dateutil==2.9.0.20240316
+types-python-dateutil==2.9.0.20240906
 typing_extensions==4.12.2
 tzdata==2024.1
 uri-template==1.3.0
-urllib3==1.26.19
-validators==0.33.0
+urllib3==1.26.20
+validators==0.34.0
 wcwidth==0.2.13
-webcolors==24.6.0
+webcolors==24.8.0
 webencodings==0.5.1
 websocket-client==1.8.0
-widgetsnbextension==4.0.11
-xarray==2023.1.0
-zipp==3.19.2
+widgetsnbextension==4.0.13
+xarray==2023.8.0
+zipp==3.20.1
diff --git a/requirements/REQUIREMENTS-JUPYTER.txt.in b/requirements/REQUIREMENTS-JUPYTER.txt.in
index ca487d08a..10b6182a7 100644
--- a/requirements/REQUIREMENTS-JUPYTER.txt.in
+++ b/requirements/REQUIREMENTS-JUPYTER.txt.in
@@ -1,4 +1,4 @@
 # requirements to run jupyter
-# constrain the requirements to packages already in REQUIREMENTS-STRICT.txt
--r ../starfish/REQUIREMENTS-STRICT.txt
+# constrain the requirements to packages already in REQUIREMENTS.txt
+-r ../REQUIREMENTS.txt
 jupyter
diff --git a/requirements/REQUIREMENTS-NAPARI-CI.txt b/requirements/REQUIREMENTS-NAPARI-CI.txt
index 91263fabb..901b3b016 100644
--- a/requirements/REQUIREMENTS-NAPARI-CI.txt
+++ b/requirements/REQUIREMENTS-NAPARI-CI.txt
@@ -1,46 +1,49 @@
 # You should not edit this file directly.  Instead, you should edit one of the following files (requirements/REQUIREMENTS-NAPARI-CI.txt.in) and run make requirements/REQUIREMENTS-NAPARI-CI.txt
-alabaster==0.7.13
+alabaster==0.7.16
 annotated-types==0.7.0
 app-model==0.2.8
 appdirs==1.4.4
+asciitree==0.3.3
 asttokens==2.4.1
 attrs==24.2.0
-Babel==2.15.0
-backcall==0.2.0
-boto3==1.34.156
-botocore==1.34.156
+babel==2.16.0
+boto3==1.35.13
+botocore==1.35.13
 build==1.2.1
 cachey==0.2.1
-certifi==2024.7.4
+certifi==2024.8.30
 charset-normalizer==3.3.2
 click==8.1.7
 cloudpickle==3.0.0
 comm==0.2.2
-contourpy==1.1.1
+contourpy==1.3.0
 cycler==0.12.1
-dask==2023.5.0
+dask==2024.8.0
 debugpy==1.8.5
 decorator==5.1.1
 diskcache==5.6.3
 docstring_parser==0.16
 docutils==0.20.1
 exceptiongroup==1.2.2
-executing==2.0.1
+executing==2.1.0
+fasteners==0.19
+flexcache==0.3
+flexparser==0.3.1
 fonttools==4.53.1
-freetype-py==2.4.0
-fsspec==2024.6.1
+freetype-py==2.5.1
+fsspec==2024.9.0
 h5py==3.11.0
 HeapDict==1.0.1
 hsluv==5.0.4
-idna==3.7
-imageio==2.34.2
+idna==3.8
+imageio==2.35.1
 imagesize==1.4.1
-importlib_metadata==8.2.0
-importlib_resources==6.4.0
+importlib_metadata==8.4.0
+importlib_resources==6.4.4
 in-n-out==0.2.1
 iniconfig==2.0.0
 ipykernel==6.29.5
-ipython==8.12.3
+ipython==8.18.1
 jedi==0.19.1
 Jinja2==3.1.4
 jmespath==1.0.1
@@ -48,9 +51,9 @@ joblib==1.4.2
 jsonschema==4.17.3
 jupyter_client==8.6.2
 jupyter_core==5.7.2
-kiwisolver==1.4.5
+kiwisolver==1.4.7
 lazy_loader==0.4
-llvmlite==0.41.1
+llvmlite==0.43.0
 locket==1.0.0
 looseversion==1.3.0
 magicgui==0.9.1
@@ -61,26 +64,25 @@ matplotlib-inline==0.1.7
 mdurl==0.1.2
 mistune==0.8.4
 mpmath==1.3.0
-napari==0.4.19.post1
+napari==0.5.3
 napari-console==0.0.9
 napari-plugin-engine==0.2.0
 napari-plugin-manager==0.1.0
-napari-svg==0.1.10
+napari-svg==0.2.0
 nest-asyncio==1.6.0
-networkx==3.1
+networkx==3.2.1
 npe2==0.7.7
-numba==0.58.1
+numba==0.60.0
+numcodecs==0.12.1
 numpy==1.24.4
-numpydoc==1.7.0
+numpydoc==1.8.0
 packaging==24.1
-pandas==2.0.3
+pandas==2.2.2
 parso==0.8.4
-partd==1.4.1
+partd==1.4.2
 pexpect==4.9.0
-pickleshare==0.7.5
 pillow==10.4.0
-Pint==0.21.1
-pkgutil_resolve_name==1.3.10
+Pint==0.24.3
 platformdirs==4.2.2
 pluggy==1.5.0
 pooch==1.8.2
@@ -90,12 +92,12 @@ psygnal==0.11.1
 ptyprocess==0.7.0
 pure_eval==0.2.3
 pyconify==0.1.6
-pydantic==2.8.2
+pydantic==2.9.0
 pydantic-compat==0.1.2
-pydantic_core==2.20.1
+pydantic_core==2.23.2
 Pygments==2.18.0
 PyOpenGL==3.1.7
-pyparsing==3.1.2
+pyparsing==3.1.4
 pyproject_hooks==1.1.0
 PyQt5==5.15.11
 PyQt5-Qt5==5.15.14
@@ -105,40 +107,40 @@ pytest==8.3.2
 pytest-qt==4.4.0
 python-dateutil==2.9.0.post0
 pytz==2024.1
-PyWavelets==1.4.1
+PyWavelets==1.6.0
 PyYAML==6.0.2
-pyzmq==26.1.0
-qtconsole==5.5.2
+pyzmq==26.2.0
+qtconsole==5.6.0
 QtPy==2.4.1
 read-roi==1.6.0
 regional==1.1.2
 requests==2.32.3
-rich==13.7.1
+rich==13.8.0
 s3transfer==0.10.2
 scikit-image==0.21.0
-scikit-learn==1.3.2
-scipy==1.10.1
+scikit-learn==1.5.1
+scipy==1.13.1
 seaborn==0.13.2
 semantic-version==2.10.0
-setuptools==56.0.0
+setuptools==74.1.2
 shellingham==1.5.4
 showit==1.1.4
 six==1.16.0
 slicedimage==4.1.1
 snowballstemmer==2.2.0
-Sphinx==7.1.2
-sphinxcontrib-applehelp==1.0.4
-sphinxcontrib-devhelp==1.0.2
-sphinxcontrib-htmlhelp==2.0.1
+Sphinx==7.4.7
+sphinxcontrib-applehelp==2.0.0
+sphinxcontrib-devhelp==2.0.0
+sphinxcontrib-htmlhelp==2.1.0
 sphinxcontrib-jsmath==1.0.1
-sphinxcontrib-qthelp==1.0.3
-sphinxcontrib-serializinghtml==1.1.5
+sphinxcontrib-qthelp==2.0.0
+sphinxcontrib-serializinghtml==2.0.0
 stack-data==0.6.3
 superqt==0.6.7
-sympy==1.13.1
+sympy==1.13.2
 tabulate==0.9.0
 threadpoolctl==3.5.0
-tifffile==2023.7.10
+tifffile==2024.8.30
 tomli==2.0.1
 tomli_w==1.0.0
 toolz==0.12.1
@@ -147,13 +149,14 @@ tqdm==4.66.5
 trackpy==0.6.4
 traitlets==5.14.3
 triangle==20230923
-typer==0.12.3
+typer==0.12.5
 typing_extensions==4.12.2
 tzdata==2024.1
-urllib3==1.26.19
-validators==0.33.0
-vispy==0.14.2
+urllib3==1.26.20
+validators==0.34.0
+vispy==0.14.3
 wcwidth==0.2.13
 wrapt==1.16.0
-xarray==2023.1.0
-zipp==3.19.2
+xarray==2023.8.0
+zarr==2.18.2
+zipp==3.20.1
diff --git a/requirements/REQUIREMENTS-NAPARI-CI.txt.in b/requirements/REQUIREMENTS-NAPARI-CI.txt.in
index 8030df5c4..3221f2457 100644
--- a/requirements/REQUIREMENTS-NAPARI-CI.txt.in
+++ b/requirements/REQUIREMENTS-NAPARI-CI.txt.in
@@ -1,6 +1,6 @@
 # requirements to run napari and CI for napari
-# constrain the CI requirements to packages already in REQUIREMENTS-STRICT.txt
--r ../starfish/REQUIREMENTS-STRICT.txt
+# constrain the CI requirements to packages already in REQUIREMENTS.txt
+-r ../REQUIREMENTS.txt
 # napari 0.4.18 made point sizes only isotropic: https://forum.image.sc/t/anisotropic-point-sizes/83388
 napari[all]>0.4.17
 pytest-qt
diff --git a/setup.cfg b/setup.cfg
index e35e6fe30..557e7c35c 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -28,7 +28,6 @@ classifier =
     Operating System :: Windows
     License :: OSI Approved :: MIT License
     Programming Language :: Python :: 3
-    Programming Language :: Python :: 3.8
     Programming Language :: Python :: 3.9
     Programming Language :: Python :: 3.10
     Programming Language :: Python :: 3.11
diff --git a/setup.py b/setup.py
index 2bf5eefbc..a6920aa50 100644
--- a/setup.py
+++ b/setup.py
@@ -30,5 +30,5 @@
     include_package_data=True,
     version=versioneer.get_version(),
     cmdclass=versioneer.get_cmdclass(),
-    python_requires='>=3.8, <3.12'
+    python_requires='>=3.9, <3.12'
 )
diff --git a/starfish/REQUIREMENTS-STRICT.txt b/starfish/REQUIREMENTS-STRICT.txt
index b8abce074..1044ae28a 100644
--- a/starfish/REQUIREMENTS-STRICT.txt
+++ b/starfish/REQUIREMENTS-STRICT.txt
@@ -1,60 +1,59 @@
 # You should not edit this file directly.  Instead, you should edit one of the following files (REQUIREMENTS.txt) and run make starfish/REQUIREMENTS-STRICT.txt
 attrs==24.2.0
-boto3==1.34.156
-botocore==1.34.156
-certifi==2024.7.4
+boto3==1.35.13
+botocore==1.35.13
+certifi==2024.8.30
 charset-normalizer==3.3.2
 click==8.1.7
-contourpy==1.1.1
+contourpy==1.3.0
 cycler==0.12.1
 diskcache==5.6.3
 docutils==0.20.1
 fonttools==4.53.1
 h5py==3.11.0
-idna==3.7
-imageio==2.34.2
-importlib_resources==6.4.0
+idna==3.8
+imageio==2.35.1
+importlib_resources==6.4.4
 jmespath==1.0.1
 joblib==1.4.2
 jsonschema==4.17.3
-kiwisolver==1.4.5
+kiwisolver==1.4.7
 lazy_loader==0.4
 looseversion==1.3.0
 matplotlib==3.7.5
 mistune==0.8.4
 mpmath==1.3.0
-networkx==3.1
+networkx==3.2.1
 numpy==1.24.4
 packaging==24.1
-pandas==2.0.3
+pandas==2.2.2
 pillow==10.4.0
-pkgutil_resolve_name==1.3.10
-pyparsing==3.1.2
+pyparsing==3.1.4
 pyrsistent==0.20.0
 python-dateutil==2.9.0.post0
 pytz==2024.1
-PyWavelets==1.4.1
+PyWavelets==1.6.0
 PyYAML==6.0.2
 read-roi==1.6.0
 regional==1.1.2
 requests==2.32.3
 s3transfer==0.10.2
 scikit-image==0.21.0
-scikit-learn==1.3.2
-scipy==1.10.1
+scikit-learn==1.5.1
+scipy==1.13.1
 seaborn==0.13.2
 semantic-version==2.10.0
-setuptools==56.0.0
+setuptools==74.1.2
 showit==1.1.4
 six==1.16.0
 slicedimage==4.1.1
-sympy==1.13.1
+sympy==1.13.2
 threadpoolctl==3.5.0
-tifffile==2023.7.10
+tifffile==2024.8.30
 tqdm==4.66.5
 trackpy==0.6.4
 tzdata==2024.1
-urllib3==1.26.19
-validators==0.33.0
-xarray==2023.1.0
-zipp==3.19.2
+urllib3==1.26.20
+validators==0.34.0
+xarray==2023.8.0
+zipp==3.20.1