diff --git a/.changeset/warm-bikes-carry.md b/.changeset/warm-bikes-carry.md
new file mode 100644
index 00000000..dee8c9a5
--- /dev/null
+++ b/.changeset/warm-bikes-carry.md
@@ -0,0 +1,6 @@
+---
+'@tus/server': minor
+---
+
+- Add `allowedCredentials` option for the Access-Control-Allow-Credentials header
+- Add `allowedOrigins` option for setting domains in Access-Control-Allow-Origin
diff --git a/packages/server/README.md b/packages/server/README.md
index 491d72d1..9335d75e 100644
--- a/packages/server/README.md
+++ b/packages/server/README.md
@@ -69,6 +69,16 @@ Max file size (in bytes) allowed when uploading (`number` |
 (`(req, id: string | null) => Promise<number> | number`)). When providing a function
 during the OPTIONS request the id will be `null`.
 
+#### `options.allowedCredentials`
+
+Sets `Access-Control-Allow-Credentials` (`boolean`, default: `false`).
+
+#### `options.allowedOrigins`
+
+Trusted origins (`string[]`).
+
+Sends the client's origin back in `Access-Control-Allow-Origin` if it matches.
+
 #### `options.postReceiveInterval`
 
 Interval in milliseconds for sending progress of an upload over
diff --git a/packages/server/src/server.ts b/packages/server/src/server.ts
index d644341e..dd06d376 100644
--- a/packages/server/src/server.ts
+++ b/packages/server/src/server.ts
@@ -219,9 +219,11 @@ export class Server extends EventEmitter {
     }
 
     // Enable CORS
+    res.setHeader('Access-Control-Allow-Origin', this.getCorsOrigin(req))
     res.setHeader('Access-Control-Expose-Headers', EXPOSED_HEADERS)
-    if (req.headers.origin) {
-      res.setHeader('Access-Control-Allow-Origin', req.headers.origin)
+
+    if (this.options.allowedCredentials === true) {
+      res.setHeader('Access-Control-Allow-Credentials', 'true')
     }
 
     // Invoke the handler for the method requested
@@ -233,6 +235,23 @@ export class Server extends EventEmitter {
     return this.write(context, req, res, 404, 'Not found\n')
   }
 
+  private getCorsOrigin(req: http.IncomingMessage): string {
+    const origin = req.headers.origin
+    const isOriginAllowed =
+      this.options.allowedOrigins?.some((allowedOrigin) => allowedOrigin === origin) ??
+      true
+
+    if (origin && isOriginAllowed) {
+      return origin
+    }
+
+    if (this.options.allowedOrigins && this.options.allowedOrigins.length > 0) {
+      return this.options.allowedOrigins[0]
+    }
+
+    return '*'
+  }
+
   write(
     context: CancellationContext,
     req: http.IncomingMessage,
diff --git a/packages/server/src/types.ts b/packages/server/src/types.ts
index 0ec93009..b1a816ff 100644
--- a/packages/server/src/types.ts
+++ b/packages/server/src/types.ts
@@ -34,6 +34,16 @@ export type ServerOptions = {
    */
   allowedHeaders?: string[]
 
+  /**
+   * Set `Access-Control-Allow-Credentials` to true or false (the default)
+   */
+  allowedCredentials?: boolean
+
+  /**
+   * Add trusted origins to `Access-Control-Allow-Origin`.
+   */
+  allowedOrigins?: string[]
+
   /**
    * Interval in milliseconds for sending progress of an upload over `EVENTS.POST_RECEIVE_V2`
    */
diff --git a/packages/server/test/Server.test.ts b/packages/server/test/Server.test.ts
index 6094b1eb..c29da467 100644
--- a/packages/server/test/Server.test.ts
+++ b/packages/server/test/Server.test.ts
@@ -165,6 +165,19 @@ describe('Server', () => {
         })
     })
 
+    it('OPTIONS should return returns custom headers in Access-Control-Allow-Credentials', (done) => {
+      server.options.allowedCredentials = true
+
+      request(listener)
+        .options('/')
+        .expect(204, '', (err, res) => {
+          res.headers.should.have.property('access-control-allow-credentials')
+          res.headers['access-control-allow-credentials'].should.containEql('true')
+          server.options.allowedCredentials = undefined
+          done(err)
+        })
+    })
+
     it('HEAD should 404 non files', (done) => {
       request(listener)
         .head('/')
@@ -252,8 +265,37 @@ describe('Server', () => {
       done()
     })
 
-    it('should allow overriding the HTTP method', async () => {
+    it('should allow overriding the HTTP origin', async () => {
+      const origin = 'vimeo.com'
+      const req = httpMocks.createRequest({
+        headers: {origin},
+        method: 'OPTIONS',
+        url: '/',
+      })
+      // @ts-expect-error todo
+      const res = new http.ServerResponse({method: 'OPTIONS'})
+      await server.handle(req, res)
+      assert.equal(res.hasHeader('Access-Control-Allow-Origin'), true)
+    })
+
+    it('should allow overriding the HTTP origin only if match allowedOrigins', async () => {
+      const origin = 'vimeo.com'
+      server.options.allowedOrigins = ['vimeo.com']
+      const req = httpMocks.createRequest({
+        headers: {origin},
+        method: 'OPTIONS',
+        url: '/',
+      })
+      // @ts-expect-error todo
+      const res = new http.ServerResponse({method: 'OPTIONS'})
+      await server.handle(req, res)
+      assert.equal(res.hasHeader('Access-Control-Allow-Origin'), true)
+      assert.equal(res.getHeader('Access-Control-Allow-Origin'), 'vimeo.com')
+    })
+
+    it('should allow overriding the HTTP origin only if match allowedOrigins with multiple allowed domains', async () => {
       const origin = 'vimeo.com'
+      server.options.allowedOrigins = ['google.com', 'vimeo.com']
       const req = httpMocks.createRequest({
         headers: {origin},
         method: 'OPTIONS',
@@ -263,6 +305,35 @@ describe('Server', () => {
       const res = new http.ServerResponse({method: 'OPTIONS'})
       await server.handle(req, res)
       assert.equal(res.hasHeader('Access-Control-Allow-Origin'), true)
+      assert.equal(res.getHeader('Access-Control-Allow-Origin'), 'vimeo.com')
+    })
+
+    it(`should now allow overriding the HTTP origin if doesn't match allowedOrigins`, async () => {
+      const origin = 'vimeo.com'
+      server.options.allowedOrigins = ['google.com']
+      const req = httpMocks.createRequest({
+        headers: {origin},
+        method: 'OPTIONS',
+        url: '/',
+      })
+      // @ts-expect-error todo
+      const res = new http.ServerResponse({method: 'OPTIONS'})
+      await server.handle(req, res)
+      assert.equal(res.hasHeader('Access-Control-Allow-Origin'), true)
+      assert.equal(res.getHeader('Access-Control-Allow-Origin'), 'google.com')
+    })
+
+    it('should return Access-Control-Allow-Origin if no origin header', async () => {
+      server.options.allowedOrigins = ['google.com']
+      const req = httpMocks.createRequest({
+        method: 'OPTIONS',
+        url: '/',
+      })
+      // @ts-expect-error todo
+      const res = new http.ServerResponse({method: 'OPTIONS'})
+      await server.handle(req, res)
+      assert.equal(res.hasHeader('Access-Control-Allow-Origin'), true)
+      assert.equal(res.getHeader('Access-Control-Allow-Origin'), 'google.com')
     })
 
     it('should not invoke handlers if onIncomingRequest throws', (done) => {