sample_geneset2.txt

GS	GeneList	Qvalues	Direction
AMIT_SERUM_RESPONSE_40_MCF10A	FOS FOSB EGR1 NR4A2 ATF3 NR4A1 RGS2 DUSP1 DCN JUN SLC16A4 ZFP36 CXCL2 CLIC4 FPR1 TP63 GM2A MCL1 GLUL KLF6 WEE1 CXCL3 TCTN2 PVR IL1A LGMN CITED2 THBS1 TOMM22 ADM NAMPT	0	UP
ANASTASSIOU_CANCER_MESENCHYMAL_TRANSITION_SIGNATURE	ASPN GREM1 MFAP5 THBS2 TIMP3 SULF1 EDNRA ACTA2 SPOCK1 TMEM158 FN1 AEBP1 COL5A2 GLT8D2 DCN RAB31 PRRX1 FBN1 LGALS1 COL6A3 CRISPLD2 OLFML2B SERPINF1 COL1A1 PCOLCE NUAK1 COPZ2 COL6A2 THY1 COL1A2 SPARC NTM C1QTNF3 CTSK LUM PDGFRB BGN FAP SFRP4 CDH11 ITGBL1 COL5A1 TNFAIP6 MMP2 INHBA COL3A1 LRRC15 MXRA5 LOXL2 PLAU SNAI2 COMP COL10A1 RCN3 COL11A1 VCAN NOX4 MMP11 ADAM12 NID2 EPYC LOX POSTN	0	UP
BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN	FABP4 ADIPOQ TUBB6 SFRP1 DPT CAV1 TNXB MFAP4 ELN OMD SPARCL1 EMCN PECAM1 IGF1 VWF RBP4 TEK ADCY2 PIK3CD NGFR ERG CD34 TNFRSF1B TGFBR2 ABCA6 ADAM11 POU2F2 TXNIP MMP3 MARCH7 RPL31 CCDC82 FOXN3 PDK4 RPL34 TF CIDEC ALDH1A1 F2R ALDH1L1 GDPD2	0	UP
BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN	MYL9 KCNMB1 TPM2 ACTG2 TAGLN AOC3 FERMT2 TIMP3 TGFB1I1 DDR2 MYH10 ZCCHC24 PTRF DLC1 EPHA3 EDNRA CAV1 ACTA2 THBS4 FLNA NAV3 SPOCK1 FHL1 KANK2 CALD1 MXRA7 FLNC SPEG OBSL1 FSTL1 SMTN CADM1 PTPRZ1 LIMS2 MYLK RGS5 SLIT3 COPZ2 CD81 MXRA8 NPR3 SNRPN ACTN1 LAMA2 TUBG2 AQP1 EXTL2 RGS4 BGN TTC28 FAP CX3CR1 PDE5A PARVA ZNF385D NPR2 SAV1 CTNND2 GPC1 HSPG2 CNN2 ACVR1 NME7 PTPN14 C9orf3 CNIH3 SLC4A3 RABGAP1 MPRIP GSTA1 SH3PXD2A AHNAK PLSCR3 DAAM1 ANO1 SNAI2 MDFI STARD13 CNPY4 NCOA1 APBA1 ERBB4 CCDC15 ADAMTS12 LIN28A ADAM12 SRPX2 COPS8 MTSS1 EFR3B TTC3 CEP41 MAPK7 LGALSL COL8A1 MYH9 KIDINS220 RTN4 C11orf80 FKBP9 ZBTB43 ITGB5 PICALM EFNA3 PTPN21 MBOAT2 RUNX1 ACSL3 KLHDC10 TMEM134 SPRED2 FBXW2 TLN2 RCAN1 VSNL1 NDUFV1 ENDOD1 CAPN2 CHMP3 PDGFD EDN2 AGPAT2 DDAH1 RIT1 SEMA5A SORT1 HIST1H2AC CAPN5 ENPP1 PERP HIST1H2AE HIST1H4H C1orf116	0	UP
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN	FOSB OGN FABP4 C7 ADH1B APOD DPT TPPP3 CFD ITIH5 C3 OMD SPARCL1 MYOC IGF1 CHL1 WISP2 PDGFRL PPL CPVL SOCS3 NAALAD2 SERPINA5 NTRK2 WNT11 APOE CD14 PTGER4 CXCL14 TMEM176B	0	UP
BROWNE_HCMV_INFECTION_2HR_UP	FOS EGR1 CHRDL1 ATP1A2 NR4A2 ATF3 ADH1B NR4A1 ECM2 RGS2 COL21A1 CFD NR4A3 MFAP4 PTGDS SNED1 SLC29A1 ICAM1 RARRES2 N4BP2L1 APOE NFKBIA MAP3K8 FYB DAZL ELANE SRCAP CXCL3 ADCY1 KIAA0368 SFPQ DHRS3 IRF1 ERP44 GCH1 ADH1A VWA5A ADH1C	0	UP
BURTON_ADIPOGENESIS_PEAK_AT_2HR	CYR61 FOS FOSB PTGS2 CTGF NR4A2 NR4A1 RHOB RGS2 DUSP1 PPP1R15A JUNB ZFP36 BTG2 CDR2L IER3 IL6 DNAJB4 CEBPD CXCL1 TNFRSF1B TNFAIP6 MYC SERPINE1 PIM1 PHLDA1 EMD BAG3 FOXC2 WEE1 MAP2K3 CDR2 LONP1 ID2 ETS2 GADD45G VEGFA THBS1 DNAJB6 ID1 DNAJB1 ADM ID3 SEMA3C KLF4 CAPN1 SLC20A1 HK2	0	UP
CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN	ADAMTS1 EGR1 MYL9 ASPN RGS1 SRPX VNN1 GEM C7 THBS2 AMIGO2 SULF1 EGR2 CCL21 GPR183 LOXL1 CXCL12 EFEMP1 PMP22 CCL19 GPNMB ISLR MOXD1 PLTP AEBP1 PTGDS SEPT6 RCAN2 MMP9 RFTN1 SERPINB9 COL6A3 COL1A1 ACSL4 BASP1 CP EVI2A COL1A2 CHST11 MYOM1 TPST1 VNN2 KCTD12 TMEM45A MAD1L1 POU2AF1 RASGRP1 TIMP1 AIM2 CD52 TNFAIP8 LUM CYTIP BGN CD2 IL7R SERPINE2 COLEC11 SLC17A9 SOCS3 HOMER1 COL5A1 MMD CYFIP2 DUSP5 ATP2B2 CCL20 SERPINE1 KLRB1 DCPS COL3A1 SPHK1 NAV2 ZNF83 MXRA5 TIMP2 INHBE ACP5 GLDC STAT4 GLS2 C9 HABP2 FURIN MCC SLC15A1 GPR88 VCAN SLC7A2 HAL CRP MAP3K5 UGCG RAB27B PRG4 NCALD S100P TNFSF4 ETS2 CYBA SLC2A9 PELI1 RAB27A EPHA1 SEL1L3 SEMA6A CAPG MGLL ASRGL1 MUC13 LGALS3 BACE2 GCH1 PLBD1 CD24 SLPI FGFR2 LSR F3 BMP2 GOT1 SLC12A2 WWC1 LGALS4 MYO1E FBP1 LXN GALNT7 CDA HPGD CDH1 GATA6 XK CNGA1 HSD17B2	0	UP
COLDREN_GEFITINIB_RESISTANCE_DN	EHF OCLN ITGB6 GRAMD1C FOXA1 C1orf116 GALNT3 SMAGP MYO1D RAB25 TMEM30B MFSD6 SLC35A3 S100A14 ERBB3 AP1M2 EXPH5 PRR15L AGR2 PTK6 SLC1A1 CYP2J2 MPZL2 MAPK13 CLDN7 FGFBP1 VAV3 TMPRSS4 TMC5 OVOL2 ELMO3 SMPDL3B CDS1 TJP2 OVOL1 RBM47 STAP2 CDH1 TSPAN1 IRF6 MYO6 SERPINB5 TBC1D8B GRHL2 CLDN4 KRT19 FXYD3 TJP3 STK39 PRSS8 SPINT1 TTC22 LAD1 SH3YL1 HMGCL LAMC2 GCNT2 ENPP4 EPPK1 LGALS9 AIM1 ZNF468 PRRG4 VAMP8 ST14 LSR LIMA1 ESRP2 BSPRY CNKSR1 MST1R DDR1 RNF141 MYH14 ELF3 REPS2 RIPK4 B3GNT3 EPN3 ENDOD1 LMO7 GCA PRKCD ATP2C2 ATPIF1 CAB39 ZNF91 CCNG2 BLNK RNF114 EPS8L2 ADK CDC42 EPHA1 BIK GPR87 ARAP2 GAB1 SCAMP2 FRMD4B ADAP1 GUK1 ACPP PRRG2 ANXA9 COBLL1 PLEKHF2 SPINK2 RAB38 TACSTD2 AKTIP ADAM28 WLS KALRN PRSS22 EPS8L1 SCEL TMEM123 RAB11FIP4 IKZF2 RHOD ZMYM6 SRPX2 TMEM40 WEE1 ZNF43 SRCAP CST6 GNAS PSD4 ZNF506 COMT AIM1L DST KRT15 HSD17B7 KLK6 CCDC57 HS3ST1 PITPNM3 FAM3C CLDN9 SPTLC3 CDH3 PIK3IP1 C1orf21 KIAA0040 DAPP1 SVIL PDE5A KCNMB4 ALDH1A3 PPL ARHGDIB PEG10 GUCY1B3	0	DOWN
COWLING_MYCN_TARGETS	MYL9 GREM1 CNN1 CRYAB TAGLN IGFBP5 COX7A1 FBLN5 STMN2 SPP1 PBX3 LBH HSPB2 TUBB2A COPZ2 CPEB1 SLC16A2 MFGE8 RND2 APH1B PVALB SYNC TK2 MMP3 COL11A1 GRIA3 NLRX1 MMP10 MYL5 SHOX2 B4GALT4 DDAH2 PRR5L	0	UP
CROONQUIST_STROMAL_STIMULATION_UP	FOS FOSB CTGF RGS1 TPM2 NR4A2 THBS2 NNMT SULF1 TSC22D3 RGS2 LOXL1 ACTA2 NOTCH3 DUSP1 SMARCD3 PPP1R15A TGM2 LAMA4 COL6A3 CCL3 OLFM1 BASP1 COL1A2 IGFBP7 SPARC CXCL2 LUM COL6A1 FSCN1 IER3 IL6 CCL4 IER2 CXCL1 IGFBP4 SERPINE1 TGFBI IGFBP3 TPM1 PIM2 NFKBIA NUPR1 GABRA5 GABBR2 VCAN SLC25A4 CXCL3 MYOF GUCY1A2 SPTBN1 TMSB4X HIST2H2AA3 ID1 SFTPB MICAL2 LOX RPS4Y1	0	UP
EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION	DES CRYAB TAGLN CASQ2 PALMD SMPX ACTA2 HBEGF FHL1 LDB3 AEBP1 COL6A3 PDLIM7 SGCD MYOM1 ITGB1BP2 MACF1 CTF1 ABLIM3 MRAS MYBPC2 MYL6B BIN1 SGCG MEF2C DTX3 TPM1 MEF2D UTRN MYH3 TNNT3 TNNI2 MYBPH MYL4 MYLPF MYL1 BCAN MYH8 MTSS1 TNNC1 CXCL10 MYBPC1 SYNGR2 TNNI1 MYH1 NEBL TNNC2 PDLIM5 MYO10	0	UP
FARMER_BREAST_CANCER_CLUSTER_2	ESRP1 ASPM MAD2L1 KIF15 PRC1 CENPA KIF4A NEK2 KIF11 CCNA2 CEP55 MELK KIF20A CCNB2 TPX2 NDC80 BUB1B CENPE NUSAP1 MRPL15 MCM4 MTFR1 NCAPG PTTG1 RB1CC1 PRKDC BUB1 RAD54B ARMC1 ATAD2 RRS1 SLC25A32	0	DOWN
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP	CXCR4 LTF CFD MOXD1 RASSF2 RBMS1 MMP9 RAB31 S100A4 CSTA RHOH COL6A3 IL10RA S100A8 CORO1A ENTPD1 CD48 RGS10 KIAA0922 HCLS1 ITGB2 PTPRC LAPTM5 GMFG LY86 LCP1 DOCK2 TYROBP CD52 LCK CD27 INPP5D CD53 CD2 PRKCB RAC2 APOC1 FCN1 CELF2 C1QB VSIG4 LST1 CD3D TNFRSF1B CD163 SLA AIF1 FCER1G CD8A UBE2L6 ALDOC PIM2 WARS CCND3 CD14 TYMP IFI30 GBP2 GLUL LILRB4 ISG20 PDE6D IFITM1 ACTB CCL5 POLR2A IL4R UBC EIF2AK2 STAT1 ADAM15 USP9X FCGR1A GAPDH SFN HLA-F AOAH RAB27A PSMB8 GZMA LCN2 FABP5 LGALS9 IL10RB	0	UP
IGLESIAS_E2F_TARGETS_UP	OGN SCG2 ADIPOQ IGFBP5 RHOB ANXA1 CXCL13 ACTA2 NID1 CDKN1C CFD CDH5 PMP22 TUBA1A CDO1 ANGPTL2 LPL FBLN2 C3 PKD2 CADM1 COL5A2 ELN DCN LAMA4 LGALS1 COL15A1 COL6A3 SERPINF1 TUBB2A COL4A1 COL1A1 COL6A2 EVL COL1A2 C1QA SPARC LAPTM5 TMEM45A CSRP1 LCP1 TYROBP ITM2A LUM MRC1 CD53 COL18A1 GNAI2 CRTAP CD34 FMO1 C1QB DAB2 RBP1 CD74 LYL1 SERPINH1 IGFBP4 GJA1 GSN TUBB LIMS1 ENPP2 COL3A1 CCND2 SEPT7 APOE NFKBIA S100A13 MFAP2 AKIRIN2 S100A11 AP4S1 ZFAND5 MCM3 ALAS2 TUBA1B ACADL DSTN GAS6 MCM5 NFIB SLC25A4 RBBP7 GADD45B ITGB1 CACYBP TIMM22 MORF4L1 LMNA LAPTM4A NID2 HSP90AA1 GNB1 HNRNPA2B1 SEPT2 ARSA C6orf25 CD47 TANK ID2 CLK1 CTSE NPTN MCM7 ITM2B KITLG ADH5 B2M ACTG1 CNN3 SKP1 DNAJA1 TMSB4X CALM2 SS18 CTSZ PCNA CA3 THBS1 SERPINB6 EED S100A6 APLP2 BZW1 CCNG1 CDC42 CRIP1 SAT1 S100A10 ANXA2 BAX CAPZA2 SMAD1 SMC2 CD9 CKS1B CYFIP1 CDC6 CTSS SCD ACADM KRT19 POSTN UGDH EMP1 AGR2 ANXA3	0	UP
JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP	GAS1 CCL2 TNC DDR2 CFH HTRA1 SDC2 CYP1B1 PMP22 TNXB DCN PHGDH PCOLCE S100A8 COL6A2 SPARC VIM COL6A1 PDGFRB SRM FMO1 DAB2 RRAS CXCL1 CDH2 SNAI1 ADA PTHLH HSPG2 MMP2 PTGS1 SERPINH1 IFITM3 GALK1 PLA2G7 MTHFD2 INHBA COL3A1 IFIT1 CDH15 ISG15 SLC3A2 IL11 PTPN22 RNASET2 CSN3 IRF7 MMP13 ASNS CCK PROCR CD68 HIF1A LAMB1 MMP12 CTSB BCL3 STAT1 B2M PDGFRA IFIT3 CTSZ CXCL6 PPIC SLPI VLDLR UPP1 SDC1	0	UP
KEEN_RESPONSE_TO_ROSIGLITAZONE_DN	OGN MGP PTGIS ATF3 IGFBP5 CLU MYH11 RGS2 ANXA1 ACTA2 SERPING1 PMP22 SERPINA3 DUSP1 SPP1 GPX3 EMP3 BHLHE40 ELN MMP9 FXYD5 CCL3 MYLK CPE COL1A2 CXCL2 CSRP1 GMFG LCP1 ENAH CYTIP BGN CD53 GNAI2 SRGN CD34 IL11RA SYN1 C1QB CXCL1 RBP1 CD74 HDC LPP COL3A1 TPM1 BNIP2 BTG3 S100A9 IL1B ARG1 TPM4 TES CD14 NUPR1 S100A11 BPGM PON1 ORM1 ALAS2 DSTN MATR3 MEF2A GADD45B ACTB HIF1A RPL18 GNB1 CAPZB CAPZA1 DNAJB2 PKP4 DYNLL1 ALDH1A1 PTGES3 MAT2B PTEN CYBA SERPINB6 S100A6 RCN2 CGGBP1 DAZAP2 ARG2 CRIP1 SAT1 TMEM59 CD9 LITAF CTSS TXN CLCN3 IL10RB SLC25A1 IL1R2 ANXA3	0	UP
KEGG_ASCORBATE_AND_ALDARATE_METABOLISM	UGT2B17 UGT1A8 UGT2A3 UGT1A3 UGT2B15 UGT1A6 UGT1A1 UGT1A9 UGDH ALDH7A1 UGT2B28 ALDH3A2 ALDH2 UGT2B4 ALDH9A1 ALDH1B1 UGT2A1	0	DOWN
KEGG_BUTANOATE_METABOLISM	EHHADH AKR1B10 ACSM3 HMGCS2 BDH1 ABAT HADH ACADS HMGCS1 ALDH7A1 ACAT1 HMGCL AACS HADHA ECHS1 ALDH3A2 ALDH5A1 PDHA1 ALDH2 ACAT2 BDH2 ALDH9A1 GAD2 PDHA2 ACSM1 L2HGDH PDHB GAD1 ALDH1B1 OXCT2 OXCT1 ACSM5	0	DOWN
KEGG_DRUG_METABOLISM_OTHER_ENZYMES	UGT2B17 UGT1A8 UGT2A3 UGT1A3 UGT2B15 UGT1A6 UGT1A1 UGT1A9 NAT2 NAT1 XDH UPP1 CDA UCK2 TPMT UGT2B28 CES2 CYP3A5 CYP3A43 GUSB UMPS HPRT1 CYP3A4 CYP3A7 UGT2B4 TK1 ITPA UCKL1 DPYS IMPDH2 CYP2A7 UGT2A1 CYP2A6 TK2 TYMP GMPS CYP2A13 UPB1 IMPDH1 DPYD CES1	0	DOWN
KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450	UGT2B17 UGT1A8 UGT2A3 CYP2B6 UGT1A3 UGT2B15 UGT1A6 UGT1A1 ADH1C UGT1A9 AKR1C3 CYP2C18 ADH6 GSTM4 GSTA2 CYP2C9 GSTZ1 ADH1A UGT2B28 AKR1C2 MGST3 AKR1C1 MGST2 GSTK1 CYP3A5 CYP3A43 AKR1C4 CYP3A4 CYP3A7 UGT2B4 ALDH3A1 EPHX1 CYP2C8 ALDH3B2 GSTP1 GSTO1 GSTM1 ADH5 ADH7 CYP2F1 GSTM2 CYP2C19 GSTA3 ALDH3B1 CYP2E1 UGT2A1 GSTA4 CYP1A2 CYP1A1 GSTM3 GSTT1 GSTA1 GSTT2 ALDH1A3 GSTM5 CYP1B1 ADH1B	0	DOWN
KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS	UGT2B17 UGT1A8 UGT2A3 UGT1A3 UGT2B15 UGT1A6 UGT1A1 UGT1A9 CRYL1 UGDH DCXR UGT2B28 UGP2 RPE GUSB UGT2B4 XYLB UGT2A1 AKR1B1	0	DOWN
KEGG_PEROXISOME	EHHADH ACOX1 AMACR FAR2 SLC27A2 PXMP2 AGPS PEX7 EPHX2 PHYH XDH ABCD3 PEX26 PEX11A PECR IDH1 ECI2 ACOT8 HMGCL ACSL5 PEX13 PEX11B ACAA1 MLYCD PEX2 PEX1 CAT HSD17B4 CROT PXMP4 GSTK1 SCP2 ACOX3 PEX19 DHRS4 PEX12 ECH1 SOD2 DECR2 DAO SOD1 ACSL3 IDH2 SLC25A17 PRDX1 GNPAT DDO ABCD4 CRAT ACOX2 ACSL1 PMVK PEX5 PEX10 NOS2 PEX16 PEX14 PEX3 MVK HAO2 BAAT PEX6 PAOX ACSL6 ABCD2 HAO1 AGXT MPV17 ABCD1 PIPOX ACSL4	0	DOWN
KEGG_PROPANOATE_METABOLISM	EHHADH PCCA HIBCH ABAT PCCB SUCLA2 SUCLG2 ALDH7A1 ACADM ACAT1 ALDH6A1 MUT HADHA ECHS1 MLYCD SUCLG1 ALDH3A2 ALDH2 ACAT2 LDHA ALDH9A1 LDHC LDHAL6B ALDH1B1 ACACA LDHB ACACB ACSS3	0	DOWN
KEGG_RETINOL_METABOLISM	UGT2B17 UGT1A8 UGT2A3 CYP2B6 UGT1A3 UGT2B15 UGT1A6 UGT1A1 ADH1C UGT1A9 CYP2C18 ADH6 DHRS9 RETSAT CYP2C9 PNPLA4 ADH1A UGT2B28 DGAT1 CYP3A5 RDH5 CYP3A43 DHRS4 CYP3A4 CYP3A7 UGT2B4 DHRS3 ALDH1A1 CYP2C8 RDH11 ADH5 RPE65 RDH8 ADH7 CYP2A7 CYP4A11 CYP2C19 UGT2A1 CYP2A6 CYP1A2 CYP1A1 RDH16 CYP2A13 ALDH1A2 CYP26B1 LRAT CYP26A1 ADH1B	0	DOWN
KEGG_STARCH_AND_SUCROSE_METABOLISM	UGT2B17 GBA3 UGT1A8 UGT2A3 UGT1A3 UGT2B15 UGT1A6 UGT1A1 UGT1A9 SI ENPP1 UGDH G6PC HK2 PGM1 UGT2B28 GBE1 UGP2 MGAM AGL GYS2 GUSB PYGB GPI UGT2B4 TREH GAA GYS1 HK3 UXS1 UGT2A1 AMY1A HK1 G6PC2 GCK ENPP3 PYGL PYGM	0	DOWN
KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION	EHHADH HMGCS2 ACADSB PCCA ACAD8 BCKDHB AUH HIBCH ABAT PCCB HADH ACAA2 ACADS HMGCS1 ALDH7A1 ACADM ACAT1 MCCC2 HMGCL ALDH6A1 ACAA1 MUT HADHA IVD DLD ECHS1 ALDH3A2 HADHB ALDH2 MCCC1 ACAT2 BCAT2 ALDH9A1 HSD17B10 BCKDHA ALDH1B1 BCAT1 DBT OXCT2 OXCT1 AOX1	0	DOWN
KHETCHOUMIAN_TRIM24_TARGETS_UP	FOS EGR1 BEX1 IGF2 HBEGF SAMD4A SPP1 TGM2 TGFB1 LGALS1 VCAM1 COL4A1 COL1A1 JUNB CP COL1A2 SPARC VIM LAPTM5 BTG2 COL4A2 UCP2 ITGAL ICAM1 CD44 CYBB TGFBR2 RBP1 SERPINE1 HCK CD38 TP53 AFP STAT1 ITGAV PDGFA RAI14 APP CDKN2B CDKN1A LGALS3 CASP1 FGFR2 KRT18 CDH1 EMP1	0	UP
KIM_GLIS2_TARGETS_UP	OGN MGP CTGF CCL2 COL14A1 DPT CCL21 CFH NID1 CXCL12 C3 MFAP4 EFEMP2 DCN S100A4 FBN1 COL15A1 VCAM1 SPARCL1 COL4A1 COL1A1 COL1A2 SPARC VIM CX3CL1 OSMR HLA-DQB1 LUM HLA-DQA1 LTB HLA-DRA PDGFRL COL18A1 HLA-DMA ICAM1 HLA-DRB1 LTBP2 SOCS3 LSP1 CCR2 HLA-DMB TGFBR2 CD74 ANGPTL4 AIF1 IFITM3 SERPINE1 ADAMTS2 MATN2 FCER1G TGFBI COL3A1 BBC3 ADAM8 MFAP2 ISG15 FCGR2A CASP4 MMP14 TLR2 CCL5 SYCP1 CXCL10 PSMB9 TSC22D1 CDCA3 PDGFRA CIDEC CXCL14 HLA-G PF4 S100A6 IRF1 PSMB8 SPON1 IGFBP2 LAD1 PYCARD POSTN	0	UP
LEE_DIFFERENTIATING_T_LYMPHOCYTE	CXCR4 MAL SELL SEPT6 ARHGAP15 RHOH FGFR1 CORO1A EVL CD48 EVI2A KIAA0922 HCLS1 ITGB2 PTPRC FLI1 LAPTM5 ARHGAP25 BTG2 ICAM2 GMFG SASH3 ARHGEF6 HDAC4 PVRIG DOCK2 PRKCH RASGRP1 ARHGDIB ITM2A EVI2B CD52 FNBP1 LCK ITK VAMP1 TNFAIP8 LTB UCP2 CD53 INPP4A GATA3 UBASH3A ITGAL CD2 IL7R TRAT1 ICOS PRKCB RAC2 DLGAP4 MAP4K1 IPCEF1 MR1 CECR1 CELF2 TCF7 CD3D SEMA4D LPXN SH2D1A HAUS2 MYCBP2 SLA CYFIP2 TRAF3IP3 AIF1 VAV1 CD247 PRKCQ IKZF1 ALMS1 FBXW12 SP110 LEF1 NUP210 FKBP5 ZNF721 GTF3A ZNF266 SATB1 TMC6 UBQLN4 CD96 ZNF160 FYB SELPLG APBB1IP CBX4 LAX1 IFNAR2 C2orf68 ZFP36L2 AQP3 DCLRE1C CCND3 ZC3H7B BRD2 AKAP13 TXNIP BTG1 ZNF148 CYTH1 RNASET2 BCL11B SRSF6 KDM5A DGKA PNISR SRRM2 USP34 ATF7IP2 DICER1 MZT2B STX16 FUBP1 SEC31B EIF4A1 ZNF586 PSMB9 SRSF7 NFATC2IP CEP350 ATP8B1 ING3 RYBP EPB41 CD3G UBE2G2 MTF2 MDM4 AP1G2 NDUFS8 SFPQ ZNF207 CDK13 PCGF3 BCL2L11 TARP TMBIM4 LNPEP SORL1 TRAPPC6A MPHOSPH9 ATP8A1 SP1 ALDH5A1 KLF13 TRIM14 SLC9A3R1 SLC46A3 MGAT4A	0	UP
LEE_LIVER_CANCER_DENA_DN	NETO2 REG1A EHHADH HSD3B2 ACSM3 ACADSB ACOX1 CYP4F2 LACTB2 CPT2 OTC SLC25A13 PCK1 EPHX2 DMBT1 PHYH ABCD3 G6PC C4BPA SELENBP1 PEX11A LIPC DCXR FABP1 HOXA5 ALDH3A2 AKR1C1 NR1H3 ME1 GCDH NDRG2 OAT TNNC2 CA3 ALDH1A1 ACSL1 MYH1 GSTO1 DPYS IL1RAP MAT1A CYP2F1 PAH KRT4 PLA2G1B MCM10 RORC CSAD PNLIP BHMT SLC1A2 CYP2E1 GLYAT BAAT PNLIPRP1 CYP7A1 HPD PRODH AASS PON1 ELANE CTRC CYP7B1 TNNI2 TNNT3 CA5A WNT10B SLC2A2 SLC27A5 PADI4 ALOX12B GPR37 RGN TRPV2	0	DOWN
LEE_NEURAL_CREST_STEM_CELL_UP	BCHE ATP1A2 CDH19 NEFL IGFBP5 NFASC ZCCHC24 COL14A1 RHOB GAP43 DLC1 PHOX2B ZEB2 INA EDNRA ANXA1 AP1S2 RASL12 SCN3A RUNX1T1 PMP22 NEFM SCRG1 TAGLN3 MOXD1 STMN2 SPP1 MITF ELK3 ROR1 DCN SERPINB9 SORBS1 LGALS1 GYPC NRXN1 TMEM204 STMN4 SGCD HOXB2 COL1A2 IGFBP7 PODXL CNR1 SNAP25 NPR3 IFI16 ALCAM CDH6 LUM CRABP1 BGN ITGA4 NGFR NNAT FAP SST CEBPD NR2F2 PCBP4 CRABP2 DPYD RBP1 EEF1A2 MSTN LRRN3 NRP2 NR2F1 KCNN2 GSN DACT1 TGFBI MEF2C TFAP2B L1CAM CYP26A1 FAM89B COL3A1 TRIM62 PCDH8 PHLDA1 PAX3 SCG3 SLIT1 SNAI2 MDFI FST NHLH1 SOX10 CELF3 S100A11 DCX STRA6 POU4F1 CHGA SLN NAGK NHLH2 TFAP2A MSX1 LZTS1 LPAR6 LIN28A LAMB1 ENC1 ST7 ARHGDIA SHC1 ARL6IP5 COMMD9 HOXA2 PDGFRA TRIL COBLL1 ST18 SLC17A6 RRBP1 DNAJC1 SH3BGRL3 GRN HMGA1 TNNC2 CRYZ NRIP1 LDLRAP1 GNRH1 S100A10 SEMA3C HAPLN1 LITAF AKR1C1 CHN2 QPRT POSTN KCNK5 C3orf52 CDH1 BMP5 L1TD1 ERBB3 PITX2	0	UP
LEIN_NEURON_MARKERS	EGR1 SYT1 RTN1 UCHL1 NEFL GAP43 SYNGR3 NDRG4 C16orf45 DPP6 HMP19 CHN1 CHGB MYO5A SNAP25 SNRPN SLC22A17 FAM49A CX3CL1 ALCAM ATP6V1G2 CYFIP2 GPR162 RYR2 CLSTN3 GABARAPL1 FAIM2 SYP PRKAR1B GRIA4 GRIA2 PTPRN PRKACA SMARCA2 CAMK2B GABBR2 CHST1 ADD2 CAMK2A GRIN2B MADD GRIA3 TUBA4A MAP2K1 NDFIP1 CALM2 SH3GL2 RAB6A MAP2K4 TRANK1 REPS2	0	UP
LIM_MAMMARY_LUMINAL_MATURE_DN	CRYAB MEIS2 TUBB6 TMEM47 SFRP1 CCL2 TGFBR3 RASL12 PDZRN3 HTRA1 CALD1 ITPKB LPL MOXD1 AEBP1 PKD2 GPX7 FSTL1 HEY2 DPYSL2 SORBS1 SPARCL1 AKAP2 GYPC COL4A1 COL6A2 TPST1 VIM COL16A1 KCTD12 FAM49A COL4A2 NES COL6A1 MAP4K4 NRTN TSPAN2 TFAP2C SLC1A3 JAG2 DAB2 LMO4 RECK SERPINH1 LTBP4 BCL11A LAMA1 IGFBP3 NTRK2 ETS1 MERTK APOE TSHZ2 FRMD4A SNAI2 SLC6A15 B4GALT6 TLE4 FOXO1 SOX10 RASA3 FZD1 EPB41L2 PCF11 GAS6 NFIB FOXN3 RAP2B EMILIN2 TINAGL1 IRS2 CCL7 TIAM2 DAPK2 AQP9 EGFR C1QBP FAS FAM171A1 FABP5 BACE2 MOB3B FAM13A CASP1	0	UP
LINDGREN_BLADDER_CANCER_HIGH_RECURRENCE	MGP MYL9 NR4A1 AEBP1 ANXA6 ADAM19 COL5A2 MCAM LAMA4 PRRX1 LGALS1 VCAM1 MYLK FYN MSN COL1A2 SPARC CSRP1 COL4A2 PTMS COL18A1 IL7R PELO SERPINH1 NRP2 PAPPA NAV2 CA6 BIRC3 RHBG VCAN ICAM3 NID2 ABI3BP UBR4 DNMT3B H1F0 IL32 NDRG2 CRIP1 MICAL2 DCAF7 PLCB4	0	UP
LINDVALL_IMMORTALIZED_BY_TERT_DN	CYR61 EGR1 AKAP12 TMEM47 NFASC ENO2 NNMT DPT MAP1B CRIP2 FN1 ISLR PER3 ELN LAMA4 AKAP2 SLC43A3 SLIT3 ARL4C ARL4D CTSK TRPV2 LMCD1 LRRC32 FAP PDPN IL6 LTBP2 CELF2 CXCL1 HSPG2 FMOD PTGES COL3A1 PAPPA MMP7 PTK7 LRRC15 SELPLG MDFI DCT EIF2B3 MMP3 CDON BLM VCAN ANTXR1 ADAM12 NAA10 CREG1 SLC7A1 KRT34 ITGB5 LHFPL2 CFB ADM CUL5 CRIP1 SAT1 COPA CYP20A1 ARHGAP5 LGALS3BP AKR1C1 AIMP2 PLOD2 CAPN5	0	UP
NABA_ECM_GLYCOPROTEINS	CYR61 MGP CTGF SRPX ADIPOQ LGI1 MFAP5 THBS2 IGFBP5 MMRN1 TNC PCOLCE2 DPT CILP ECM2 FBLN1 NID1 THBS4 FN1 EFEMP1 SLIT2 IGFBP6 FBLN2 FBLN5 SPP1 TNXB MFAP4 AEBP1 EFEMP2 LAMB2 SNED1 ELN LAMA4 FBN1 LAMC1 SPARCL1 CRISPLD2 EMILIN1 LTBP3 RELN PCOLCE SLIT3 SPON2 MMRN2 IGFBP7 SPARC SVEP1 LAMA2 VWF WISP2 LAMA5 BGLAP COCH LTBP2 MFGE8 VWA1 FGL2 TNFAIP6 NOV NDNF NELL2 THBS3 LTBP4 IGFBP4 MATN2 LGI2 TGFBI LAMA1 FGB IGFBP3 LAMB4 LTBP1 PXDN NTN3 EDIL3 MXRA5 SLIT1 MATN4 MFAP2 WISP3 NELL1 COMP IBSP AMBN FNDC8 NTN1 ECM1 AGRN IGFALS CRELD1 MEPE DMP1 TNN WISP1 GAS6 SBSPON FGA COLQ VWA7 POMZP3 TNR CRIM1 MATN3 MATN1 FRAS1 SRPX2 NTNG1 LAMB1 NID2 EMID1 ABI3BP EMILIN2 CRELD2 TINAGL1 DSPP VTN ELSPBP1 LAMC3 FGG USH2A FGL1 AMELX IGFBP1 THSD4 ZP2 AMELY TECTA THBS1 MFAP1 VWA9 MFAP3 TSKU SPON1 FBN2 IGFBP2 LAMC2 VWA5A POSTN LAMA3 LAMB3 DMBT1	0	UP
NAGASHIMA_EGF_SIGNALING_UP	CYR61 FOS FOSB EGR1 CTGF NR4A2 GEM ATF3 EGR3 NR4A1 EGR2 HBEGF NR4A3 DUSP1 BHLHE40 JUN MAFF JUNB ZFP36 DUSP2 PLEKHO2 IER3 NAB2 IER2 EPHA2 TRIB1 AEN MYC DUSP5 AREG KLF10 TNFRSF12A ARC PHLDA1 FOSL1 KBTBD2 MCL1 DLX2 KDM6B KLF6 EGR4 LIF TIPARP RYBP ETS2 ID1 DNAJB1 BCL10 ID3 HES1 SPRED2 TNFRSF11B EDN1 NEDD9 F2RL1	0	UP
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP	THBS2 CCL2 NNMT CFH EFEMP1 GPNMB GZMK PLTP C3 F13A1 DCN S100A4 ARHGAP15 MS4A4A LY96 ITGAM FCGR2B SLC15A3 C1QA CSF1R KYNU C1S DOCK2 NCKAP1L IFI44L TIMP1 WISP2 HLA-DQB1 CD52 LUM MRC1 HLA-DRA HLA-DPA1 NCF4 FAP HSPA6 C1QB VSIG4 ITGBL1 CD163 HLA-DRB4 CD44 TNFAIP6 SLA AIF1 SERPINE1 MME BIN2 SLAMF8 LILRB1 SIGLEC1 CD14 APOL1 ECM1 IFI30 CXCL9 FCGR2C ISG20 LYZ SRPX2 CCL5 IL4R CXCL10 THBS1 CFB S100A6 CTSC TMEM176B PDE4DIP FHL2 GZMA SERPINA1 CCL13	0	UP
PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP	BAG2 CRYAB MEIS2 C8orf4 CAV2 HDGFRP3 PRKCDBP NID1 ENOX1 PLTP FBLN5 CDK14 EMP3 FSTL1 LBH WIPF1 TGM2 RFTN1 SERPINB9 EMILIN1 TMEM204 PRUNE2 RGS5 NUAK1 RBMS3 EHD2 CCDC85B C1QA LAPTM5 GMFG LCP1 PLXDC1 TNFAIP8 PKIA EFS ZNF423 TCF4 NFATC1 CACNA1C NR3C1 CELF2 APBB2 ZFP36L1 MMP2 RBP1 CADM4 CLEC7A MATN2 LRIG1 GSN BMP7 TGFBI TYRO3 ETS1 EYA4 AR GLI1 ZHX3 PTPN12 TP63 FGD1 SEPT4 CSDC2 GNA14 APOA1 GMPR IL2RG SARDH RPL14 IARS DOC2B PTPN1 RPL22 ART3 ALDH1B1 NFIX MCF2L GSTO1 TMSB4X SIPA1L1 SMAD5 LRRK1 TAOK3 LASP1 CAMKMT PCBD1 PAICS SPIN1 SEPT11 LITAF NEDD9 SNX24 MVP CPD ZG16 HMGA2 TTC39A	0	UP
PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN	KCNMB1 LMOD1 FAM129A PTGIS TNS1 ID4 MYH11 LHFP MAP1B RASL12 CSRP2 MXRA7 PKD2 PRELP SUSD5 JAM3 MYLK ACTC1 PAM SOD3 TPD52L1 MAGED2 GRK5 PMEPA1 NOV GJA1 FMOD EID1 RABGAP1 PFKM TPM1 HSPB1 PKIG DSTN CRIM1 MYLIP EGFR ADCY9 EMP2	0	UP
PETRETTO_CARDIAC_HYPERTROPHY	OGN ASPN TAGLN MFAP5 PDLIM3 ANXA1 LOXL1 ACTA2 NID1 FN1 EFEMP1 LPL FSTL1 COL5A2 FBN1 LTBP3 ARID5B OSBPL8 ST3GAL6 CD44 ENPP2 IGFBP3 TM4SF1 TUBA1B CRIM1 TUBA1C ACTB DDX3X CPNE3 RTN4 SNAP23 ANXA4 ABAT	0	UP
PETROVA_PROX1_TARGETS_DN	AHNAK2 SRPX MLLT11 CAP2 CCL2 NNMT AXL FAM107A ITGA5 ANXA6 EMP3 NRP1 PRNP NUAK1 ICAM2 ARHGDIB RGS4 ARHGAP22 TRIM22 SRGN FAP SELP RAC2 IL6 LTBP2 APBB2 RRAS CDH2 CD44 LPXN LYL1 SERPINE1 TFEC PFKM TPM1 RNASE1 PLAU LDHB IGF2BP3 PLA2G4A PDLIM4 GBP2 MMP14 VCAN PROCR NRCAM TANK ARL6IP5 STAT6 KRT7 BMP6 CD59 TCN2 SMURF2 MAPKAPK3 TRAM2 IL32 SLC38A6 PRKACB TNFRSF21 LY75 GLCE	0	UP
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP	ADAMTS1 MYL9 ANK2 TAGLN GUCY1A3 GUCY1B3 C7 FERMT2 IGFBP5 CLU TNS1 DPYSL3 HSPB8 FLRT2 ARHGAP29 CCL2 NNMT TNC DDR2 IL33 C8orf4 SULF1 CAV2 PTRF RBPMS CCL21 WWTR1 LOXL1 ACTA2 SERPING1 FAM107A CXCL12 COX7A1 FN1 CDH5 CYP1B1 PMP22 DCLK1 CCL19 CSRP2 CALD1 GPNMB KCNMA1 C3 MFAP4 PTGDS FSTL1 CD93 MMP9 P2RY13 LAMA4 PRRX1 FBN1 C1R LAMC1 COL15A1 VCAM1 SPARCL1 EMILIN1 COL4A1 GPRC5B MYLK COL1A1 PCOLCE EMCN RGS5 C10orf10 RGL1 CP THY1 TDO2 COL1A2 IGFBP7 C1QA SPARC KCTD12 C1S ARHGEF10 VWF COL4A2 OSMR DOCK4 LUM COL6A1 ENG PLA2G4C IRAK3 COL8A2 PDPN APOC1 LIFR SLC1A3 NR2F2 PARVA GJC1 C1QB A2M DAB2 RRAS CDH11 RARRES2 RASSF4 CYBRD1 HSPG2 LPAR1 ADAMTS9 SERPINH1 ITGA9 CETP GJA1 PLA2G2D ENPP2 FAM198B COL3A1 TPM1 APOE CYP26B1 MXRA5 SLAMF8 C2 CMKLR1 RAB13 PGF CCDC102B CHI3L1 WISP1 TLR4 CXCL9 ATOX1 KCNJ10 NAGK NFIB ANTXR1 SLCO2B1 LAMB1 ACVRL1 ABI3BP CXCL10 WLS CD63 PDGFRA RND3 ZNF226 FAM114A1 EPHX1 TMEM176A RAI14 TJP1 TNS3 CFB CTSC PDLIM5 CXCL11 TMEM176B ADAMDEC1 CYP27A1 SEPT10 NPL WDFY3 PPIC RPE MARCKS FUCA1 YAP1 CYFIP1 NR1H3 RHOBTB3 ABCC3 IFI27 PAPSS2 IDH1 DHRS7B HNMT ADRA2A PLD1 IL18 ASPM	0	UP
PID_INTEGRIN1_PATHWAY	THBS2 TNC ITGA7 NID1 FN1 SPP1 ITGA5 LAMB2 F13A1 COL5A2 TGM2 LAMA4 ITGA1 JAM2 FBN1 LAMC1 VCAM1 COL6A3 COL4A1 COL1A1 COL6A2 COL1A2 CSPG4 CD81 LAMA2 COL6A1 LAMA5 ITGA4 COL18A1 COL5A1 ITGA9 COL7A1 TGFBI LAMA1 FGB COL3A1 PLAU CD14 COL11A2 COL2A1 MDK PLAUR COL4A4 FGA ITGA8 COL11A1 ITGA10 ITGB1 LAMB1 COL4A5 VTN ITGA3 FGG ITGAV COL4A3 VEGFA COL4A6 THBS1 ITGA6 LAMC2 ITGA2 LAMA3 LAMB3	0	UP
REACTOME_MUSCLE_CONTRACTION	MYL9 LMOD1 DES TPM2 ACTG2 DMD MYH11 ACTA2 CALD1 ITGA1 SORBS1 MYLK VIM TLN1 MYBPC2 MYL6B TNNT2 TNNT1 TCAP TPM1 VCL MYL3 ACTN2 TPM4 MYH3 TNNI3 MYL2 SORBS3 TNNI2 MYL4 MYL1 TPM3 MYH8 TNNC1 MYH6 MYBPC1 CALM1 MYL6 CALM3 NEB TNNI1 CALM2 ITGB5 TNNC2 MYL12B TMOD1	0	UP
REACTOME_RESPIRATORY_ELECTRON_TRANSPORT	ETFDH ETFA NDUFS1 SDHB SDHC COX5A SDHD NDUFS2 NDUFB7 CYC1 NDUFA10 NDUFA9 NDUFS4 SDHA NDUFB3 NDUFS3 NDUFS7 UQCRFS1 UQCRC1 UQCRC2 CYCS COX5B NDUFV1 NDUFA8 NDUFB6 NDUFC2 NDUFA6 UQCRQ ETFB NDUFC1 COX6A1 NDUFB5 COX7B NDUFB2 NDUFA5 NDUFA7 NDUFAB1 COX8A COX6B1 NDUFS6 NDUFA2 UQCR11 COX6C NDUFA1 NDUFV2 UQCRH COX4I1 NDUFB4 COX7C NDUFB1 NDUFS5 NDUFA13 NDUFB8 NDUFS8 NDUFA3 COX7A2L UQCRB NDUFA4	0	DOWN
REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_	ETFDH ETFA NDUFS1 SDHB SDHC COX5A SDHD NDUFS2 NDUFB7 CYC1 NDUFA10 NDUFA9 NDUFS4 SDHA NDUFB3 ATP5D NDUFS3 ATP5B NDUFS7 UQCRFS1 UQCRC1 UQCRC2 ATP5G1 CYCS COX5B NDUFV1 NDUFA8 NDUFB6 NDUFC2 NDUFA6 ATP5F1 UQCRQ ETFB NDUFC1 COX6A1 NDUFB5 COX7B ATP5A1 ATP5C1 NDUFB2 ATP5J2 NDUFA5 NDUFA7 NDUFAB1 COX8A COX6B1 NDUFS6 NDUFA2 UQCR11 COX6C ATP5O ATP5J ATP5H NDUFA1 NDUFV2 UQCRH COX4I1 NDUFB4 COX7C ATP5L NDUFB1 NDUFS5 ATP5I NDUFA13 NDUFB8 NDUFS8 NDUFA3 COX7A2L UQCRB ATP5E NDUFA4 UCP1 UCP3 UCP2	0	DOWN
REACTOME_SMOOTH_MUSCLE_CONTRACTION	MYL9 LMOD1 TPM2 ACTG2 MYH11 ACTA2 CALD1 ITGA1 SORBS1 MYLK TLN1 MYL6B TPM1 VCL TPM4 SORBS3 TPM3 CALM1 MYL6 CALM3 CALM2 ITGB5 MYL12B	0	UP
REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT	ETFDH BSG SLC16A1 SUCLA2 ETFA SUCLG2 IDH1 NDUFS1 DLAT IDH3A PDK3 SDHB SDHC COX5A PDHX SDHD NDUFS2 NDUFB7 MDH2 DLD CYC1 NDUFA10 SUCLG1 NDUFA9 ACO2 NDUFS4 SDHA NDUFB3 ATP5D NDUFS3 ATP5B PDHA1 NDUFS7 UQCRFS1 UQCRC1 FH UQCRC2 ATP5G1 CYCS NNT COX5B NDUFV1 PDK2 NDUFA8 NDUFB6 NDUFC2 DLST NDUFA6 ATP5F1 UQCRQ ETFB IDH3B IDH3G NDUFC1 COX6A1 NDUFB5 COX7B ATP5A1 ATP5C1 NDUFB2 ATP5J2 CS NDUFA5 NDUFA7 SLC16A3 NDUFAB1 COX8A COX6B1 NDUFS6 NDUFA2 LDHA UQCR11 PDK1 COX6C ATP5O ATP5J IDH2 ATP5H NDUFA1 NDUFV2 UQCRH COX4I1 NDUFB4 COX7C ATP5L NDUFB1 PDPR NDUFS5 ATP5I NDUFA13 NDUFB8 NDUFS8 NDUFA3 L2HGDH PDHB COX7A2L OGDH UQCRB ATP5E PDK4 NDUFA4 UCP1 SLC16A8 UCP3 LDHB UCP2 PDP1	0	DOWN
RICKMAN_HEAD_AND_NECK_CANCER_F	CHRDL1 DES ZFPM2 TPM2 ANK2 PTGIS CASQ2 SMPX APOD THBS4 FHL1 CYP1B1 DCLK1 MYOT CHGB ACTC1 IGF1 ABCA8 PKIA MYBPC2 EEF1A2 ENO3 ACTA1 TPM1 CST1 ACTN2 CKM MYL2 TNNI2 MYLPF MYL1 SLN TPM3 CSRP3 TTN TNNC1 PDK4 MYBPC1 MYH2 NEB TNNI1 MYH1 PLA2G2A TNNC2 MB HSPB3	0	UP
ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER	NETO2 PBK APOBEC3B GGH ASPM PLEK2 ECT2 E2F8 MAD2L1 KIF15 MAPK13 HMMR CA2 PRC1 CENPA KIF4A TTK NEK2 DSG2 GMNN KIF11 CCNA2 CEP55 AURKA MELK CCNB1 DLGAP5 OIP5 GINS1 TOP2A DTL SLC25A15 KIF20A ZWINT CHEK1 STIL DPP3 CDC20 RAD51AP1 CCNB2 EBP HN1 MKI67 FOXM1 DHFR TPX2 CKS2 CDC6 EZH2 NDC80 BUB1B CENPF HELLS KIF18B SMC2 FBXO5 COMMD8 CENPE KIF23 LMNB1 NUSAP1 TMPO KIF2C RACGAP1 CCNE2 ESPL1 ASF1B KIAA0101 MCM4 LSM4 CDCA8 SAC3D1 MCM2 CDK1 SMC4 BRCA1 TYMS TK1 KIF14 NCAPG BIRC5 NCAPH RPA3 UBE2C HMGA1 SPAG5 AURKB PTTG1 SLC38A1 KPNA2 BID PCNA HJURP MRPS15 CENPM H2AFX POLQ DNMT3B BUB1 FANCI PAFAH1B3 HSPB11 RRM2 TMSB10 CDCA3 DBF4 DTYMK HMGB2 PLK1 ATAD2 DNA2 ERCC6L ACACA FEN1 H2AFZ CHAF1B GINS4 MCM10 KIF20B UBE2S TRIP13 CCNF CDKN2A EIF4EBP1 KIFC1 CELSR3 E2F1 GTSE1 PAQR4 MYBL2 LRP8 TACC3 POLA2 ANP32E SHCBP1	0	DOWN
SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION	ADAMTS1 CTGF TAGLN TGFB1I1 ID4 CAV1 CXCL12 SDC2 FBLN2 FBLN5 LAMB2 FSTL1 AMOTL2 COL5A2 FBN1 COL1A1 PCOLCE JUNB RGS10 CSRP1 WISP2 TGFB3 PDGFRB BGN ST3GAL5 SLC16A7 CEBPD LTBP2 CDKN2C IL6ST COL5A3 GJB3 MMP11 ABCB6 IL1RL1 TNFRSF1A QSOX1 IFNGR1 CACNB3 APP IRF1 ID3 TNFRSF11B ATP1B1 EDN1 DDR1 VLDLR PLOD2	0	UP
SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_DN	SFRP1 PRPH FXYD6 ELAVL4 GAP43 CXCL12 NEFM TAGLN3 MXRA7 FBLN5 HMP19 PRRX1 LIMS2 OLFM1 NUAK1 BASP1 SPON2 NNAT AMPH WNT5B CALCB CRMP1 HIC1 IGFBP4 CHD3 INHBA TGFBI NTRK2 PCDH8 ELAVL3 PRMT1 HMX1 LYPD1 TUBB3 GNA14 RASA3 HTR3B STMN1 TUBA3C AMHR2 TUBA1C ENC1 COL8A1 CALCA TUBA4A MTCH1 HSPA8 KPNA2 PLAT SUMO3 ZWINT	0	UP
SCHOEN_NFKB_SIGNALING	CYR61 PTGS2 CTGF IGFBP5 CCL2 SULF1 FN1 PMP22 SERPINA3 C3 MMP9 BCL6 CXCL2 TPST1 TNFRSF9 HHEX IGFBP3 NFKBIA IL1B BIRC3 CSF2 GADD45B PTGER4 CDKN1B JAG1 IL1A THBS1 PTX3 KLF4 EDN1 CTSS NUAK2	0	UP
SENESE_HDAC2_TARGETS_DN	MYL9 CRYAB TAGLN BEX1 NEFL MFAP5 SDPR TIMP3 CLU CAP2 ID4 ZCCHC24 SYT11 OLFML3 LOXL1 NRXN3 SDC2 TMEM100 IGFBP6 GPNMB SPP1 TCEA2 EFEMP2 BNC2 COL5A2 LBH S100A4 COL1A1 IGFBP7 LUM PPP2R2B AQP1 SSBP2 ZBTB20 DTNA FADS2 SCARA3 CDH11 LSP1 BCAM MSLN MATN2 DACT1 TNNT2 COL3A1 TPM1 RASA4 SEMA3B NPTXR KRT81 MYL2 KRT17 RHOBTB1 INSIG1 GSG1 ZNF362 COL11A1 NFIB ALDH3B1 TNNC1 PTCH1 SCEL SQLE JPH3 THUMPD1 UNKL NPPB KRT14 JAG1 HDAC2 PSPH ETAA1 PDE1C GALNT2 FKBP9 CXCL14 TNS3 MMP24 SORL1 EGF LOX PDLIM1 EDN1 DEPDC1 WNT5A MGAM EDN2 JUP TRIM2 PLCE1 SCD PLAC8 GSTM4 PKP2	0	UP
SERVITJA_ISLET_HNF1A_TARGETS_UP	VIP UCHL1 MEIS2 FGF13 NEFL GUCY1A3 AKAP12 ATF3 THBS2 EGR3 TMEM47 CCL2 ID4 EGR2 DPT GAP43 PHOX2B ITGA7 ANXA1 CXCL13 HTRA1 CXCL12 EFEMP1 CYP1B1 PMP22 DCLK1 DKK3 STMN2 HMP19 AEBP1 EFEMP2 COL5A2 MCAM SV2B TGM2 FBN1 LGALS1 VCAM1 SPARCL1 DNM1 PCOLCE SLC15A3 RBMS3 MSN THY1 CNR1 ITGB2 ZFHX4 VIM LAPTM5 TNFAIP2 C1S NTM CHL1 ARHGDIB HLA-DQA1 COL6A1 TGFB3 BGN RAB6B COL18A1 SERPINE2 PLXND1 SCARA3 MAP4 ADCY7 C1QB FADS3 CDH11 PTN LY6H DNM3 FGF14 SERPINH1 IFITM3 GALK1 KCND2 CNN2 NR2F1 CACNA2D3 MAF NOL3 COL3A1 DUSP26 SNCG GRM7 PTPRO STXBP5L APOE SEPT4 MICAL1 TIMP2 RNASE1 SNAI2 SEMA4F NOTCH2 TGFB2 SNCA SLC6A15 EPHA5 SOX2 FST RBFOX1 CSF1 PLA2G4A CACNG5 REST GSTA4 MMP14 AMY1A WISP1 EPB41L2 ADCYAP1 ADCYAP1R1 PROCR CAMK4 IFITM1 FABP7 CIDEA RAB38 ELAVL2 SMAD3 HPS1 OPLAH NEBL PARP3 CYBA STK17B ASS1 NDRG2 CTSC GAB1 BLVRB CAPG ANXA2 PYGB ACOT7 IFIT2 LGALS3 PNLIPRP2 ABCC3 PRKG2 SERPINB1 POSTN PLCB4 SLC16A1 SDC1 SPINK1	0	UP
SMID_BREAST_CANCER_LUMINAL_A_UP	FOSB OGN CHRDL1 ASPN ATP1A2 ZBTB16 RTN1 LMOD1 FABP4 ADIPOQ HLF ADH1B PTGER3 MYH11 COL14A1 DPT CILP ITGA7 FBLN1 CFD FHL1 LEPR ITIH5 DUSP1 MFAP4 G0S2 F13A1 HBB OMD RAI2 PNMA2 HOXB2 SVEP1 PLIN1 LRRC17 BTG2 LAMA2 IGF1 ABCA8 ATRNL1 WISP2 RBP4 SFRP4 PTN PTHLH AREG LEP CYP4B1 C1orf21 STC2 ENPP2 LIPE GFRA1 TIMP4 CPA3 GPD1 DHRS2 SPTAN1 TNN MAP3K12 PGR PCSK5 ESR1 NKX3-1 ELOVL2 CIDEC CXCL14 TAT RUNX1 PDCD4 SCUBE2 SLC26A3 MAOA ADRA2A MYB HOXB6 NAT1 PSD3 PPARG HMGCS2	0	UP
SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP	APOBEC3B PDSS1 ASPM ECT2 E2F8 MAD2L1 KIF15 HMMR PRC1 CENPA KIF4A TTK NEK2 KIF11 CCNA2 CEP55 AURKA MELK HMGB3 CCNB1 DLGAP5 HCCS OIP5 GINS1 TOP2A TXN KIF20A ZWINT CHEK1 STIL QPRT CDC20 CCNB2 HN1 MKI67 ITCH MIS18A FOXM1 TPX2 ORMDL2 CKS2 EZH2 NDC80 BUB1B CENPF KIF18B FBXO5 CDKN3 CENPE MRPL12 LMNB1 RAD51 NUSAP1 TXNRD1 CENPN TMPO MRPL15 KIF2C RACGAP1 CCNE2 RNASEH2A ESPL1 MCM4 COX7B CDCA8 HIST1H4B MCM2 CDK1 KIF14 C20orf24 NCAPG BIRC5 NCAPG2 NCAPH UBE2C TIMM10 DSN1 DNAJC9 SPAG5 NUTF2 AURKB PTTG1 CCT5 KPNA2 FAM64A HJURP POLQ PSMA7 BUB1 TIMELESS PFDN6 SNRPF RRM2 CDCA3 RAD54B PSMD12 SNRPC H2AFV VRK1 NME1 PLK1 POLR2K SNRPG FEN1 GTPBP4 H2AFZ TCEB1 TROAP MCM10 CDC45 TUBA1C UBE2N NUP93 CDK2 SHMT2 BYSL PKMYT1 MCM6 UBE2S DSCC1 EXO1 MARS LAGE3 JMJD6 DDX39A BLM DONSON STMN1 TUBA1B TRIP13 MCM3 KIFC1 STIP1 E2F1 GMPS NUDT1 XPOT CENPI CDC25A GTSE1 MYBL2 RFC4 TACC3 SLC7A5	0	DOWN
TOMLINS_PROSTATE_CANCER_DN	GAS1 TPM2 CNN1 MEIS2 PCP4 AKAP12 C7 CLU TGFB1I1 SGCE PTRF RBPMS MEIS1 FHL1 PMP22 SPG20 SCRN1 DAAM2 PPP1R12B ATP2B4 SMTN LAMA4 MYLK GATM SVIL TACC1 ST5 GSN LPIN1 BTG3 VCL DST CYLD HMGN4 MYOF ZNF516 CALM1 ITGB4 LGALS3 SEC23A	0	UP
TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN	FOS FOSB SYNM MGP ATP1A2 ZBTB16 ACTG2 CNN1 CRYAB TAGLN ATF3 ADH1B GPM6B SFRP1 ID4 MYH11 ANXA1 BACH2 CAV1 ACTA2 CFD CADM1 SORBS1 MYLK CX3CL1 GHR PTN AK5 CYB5R2 PDZK1 NTRK2 MMP7 PI15 ATP10D KRT17 HIVEP3 NFIB KRT5 GABRP ZNF573 IQCA1 CSNK1A1 KRT14 SCGB2A2 SENP6 ELF5 RCAN1 ELF3 MAOA OXR1 SERPINB5 PIGR PROM1	0	UP
TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP	ASPN RGS1 THBS2 SULF1 CILP ZEB1 CD69 EDNRA CXCR4 TIE1 FN1 AEBP1 COL5A2 WIPF1 PRRX1 FBN1 COL6A3 COL1A1 THY1 ASAP1 COL1A2 SPARC IGF1 PLXDC1 IFI44 PLXNC1 BGN C5AR1 HSPA6 COL5A1 INHBA COL3A1 LRRC15 MXRA5 COMP AGTPBP1 WISP1 UXS1 LYZ COL11A1 VCAN ADAM12 RAP2C LAMB1 SSR1 COL8A1 ZNF117 DOCK1 FBXO28 NAA15 SMCHD1 MICAL2 LOX POSTN ENPEP SPAG9 PRC1 GNA13	0	UP
UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN	CYR61 ADAMTS1 EGR1 PTGS2 APOLD1 NR4A2 GEM ATF3 EGR3 NR4A1 EGR2 RGS2 HBEGF NR4A3 DUSP1 KLF2 HLX ZFP36 CXCL2 CREM ARID5B SELE MAP3K8 ELL2 MCL1 PDK4 CITED2 FOSL2 KLF4 RCAN1 NEDD9 F3 BMP2 NDRG1 KCNJ2	0	UP
VANHARANTA_UTERINE_FIBROID_DN	EGR1 NR4A2 ATF3 ADH1B TFPI PTGER3 LEPR KLF2 MOXD1 EFHD1 DFNA5 TNXB SOX17 BCL6 C1R MS4A4A JUN GSTM5 WFS1 MAFF C1S ABCA8 FAM65B CBX7 GIMAP6 GATA2 DAPK1 NR3C1 APOL3 IER2 HIVEP2 RARRES2 MDFIC TRIB1 RBP1 PHYHIP LTBP1 RASA4 ODC1 BIRC3 RARRES3 MSX1 NFIB GADD45B PTCH1 MAP3K5 KLHL2 ABLIM1 CITED2 RTN3 SMAD7 EZR ADD3 PAWR KLF4 PDLIM1 HOXA5 ERAP1 NDRG1 NAMPT PLCE1 CXADR KLF5	0	UP
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_DN	REG1A ABCG2 ADH1C AKR1C3 NAT2 HSD17B2 KIAA1324 NAT1 DHRS11 OTC SLC4A4 CAPN9 HMMR CA2 TFF3 CALML4 ETHE1 TMC5 GOLM1 GMDS GPA33 REG3A ATP10B ADRA2A PIP5K1B HGD TMPRSS2 CFTR GCNT3 VILL GCNT1 FXYD3 GSDMB PRSS3 BTNL8 SERPINB1 LGALS4 DDT DPP3 GOT1 LPCAT4 SULT1A1 CES2 ALDOB PRSS2 TPD52 TM4SF20 SLPI CYC1 XRCC4 BTD AKR1C1 HRASLS2 EPN3 RER1 MLPH POLD4 ABCG5 KCNK10 IFT57 BLNK PCBD1 CLDN15 CRIP1 NDUFA7 BLVRB DERL1 COX8A VPS28 ALDH3A1 MUC1 AADAC DOT1L SYBU AK1 S100P RPS27L SNRNP25 RBM19 CLDN18 SSNA1 SSTR1 ZBTB7B ISG20 NMU CPS1 PTPRN2 GP2 GATA4 TFF2 ODAM SST SULT1C2 ENTPD3 HBB	0	DOWN
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP	GAS1 MGP GUCY1A3 THBS2 TIMP3 AMIGO2 DDR2 ARMCX1 MYH10 SULF1 CAV2 HDGFRP3 EDNRA WWTR1 THBS4 AXL SPOCK1 TRPC1 FN1 EFEMP1 CYP1B1 CALD1 SLIT2 LPL GPNMB MOXD1 CDK14 AKT3 QKI SPP1 DFNA5 FSTL1 RBMS1 PRELP COL5A2 CEP170 RAB31 PRRX1 BCL6 FBN1 COL15A1 COL4A1 GFPT2 TIAM1 CPE NUAK1 FMO2 COL1A2 SPARC CHST11 MAGEH1 TMEM45A ARL4C LAMA2 NTM ZNF532 SNX10 TWIST1 CDH6 DSE HLA-DQB1 BGN ZNF423 MAFB FAP APOC1 IL6 SLC1A3 SLC2A3 SFRP4 LTBP2 DAB2 CDH11 ITGBL1 CD163 TNFAIP6 PDGFC ST3GAL1 ADAMTS2 PLA2G7 C3AR1 STC2 INHBA EPHA4 IGFBP3 COL3A1 ALOX5 BICD1 PLAU SNAI2 IBSP IGF2BP3 SOHLH2 ESM1 ANGPT2 IL24 COL10A1 FKBP14 TMEM132A TLR2 GDAP1 CCDC88A WNT2 WISP1 BCAT1 ADAMTS12 COL11A1 VCAN NOX4 MMP11 MSR1 ACTL8 PIK3R5 BMPR1B ANTXR1 ADAM12 HEY1 NID2 GIGYF2 COL8A1 NIPBL CST4 EGFL6 IL1RAP PLXDC2 THBS1 SNF8 HES2 NT5E AUTS2 SOD2 LOX SEPT11 PLOD2 RARRES1	0	UP
WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN	GAS1 TCEAL2 FLRT2 ID4 ARMCX1 SULF1 CAV1 SERPING1 SLIT2 IGFBP6 C3 ATP2B4 HBB BNIP3 ELOVL5 RHOQ TIAM1 CPE RGL1 BASP1 PODXL SH3BP5 SPRY1 DOCK4 TTC28 IFITM2 CELF2 DAB2 MNDA RUFY3 CLIP4 DPYD PTGS1 NISCH TMX4 PLSCR3 SNCA CFI WT1 SRSF5 KDR PARP6 PROCR ST13 WSB1 IL1R1 EEF1A1 N4BP2L2 SSBP3 IFT52 FRMD4B PLSCR4 CTDSP2 PDGFD LGALS8 CLIC5 RARRES1	0	UP
WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP	ETNK1 ESRP1 DSC2 RNF128 GALNT3 MAP7 NQO1 ECT2 TMEM30B SLC35A3 TOX3 S100A14 ERBB3 FZD5 NUDT15 PDZD8 CEBPG GFPT1 PERP GALNT4 PBLD CA2 EDEM3 IQGAP2 KLF5 SLC35A2 CYP51A1 RALA ABCD3 PLS1 GMDS MYO10 SYTL2 ELOVL6 SAR1B F11R SFXN1 MYO6 KCNK1 C3orf52 LLGL2 SLC39A14 GALNT7 SLC35D2 SH2D4A PLAC8 STK39 TSPAN8 CPD EPCAM DDAH1 ABHD2 HN1 ABCC3 HIGD1A DOK4 ITGA6 TPD52 CASK CD24 TM9SF3 HEPH MECOM PHLDA2 ARHGAP12 ATP1B1 FDFT1 VSIG10 CMPK1 ETFB PDIA4 LRRC8B SGSM3 SEC24A COX7A2 NET1 KDELR2 TMEM62 CD164 BAG1 PDIA3 GGT1 SYT13 BZW2 SFN MUC1 SEC22B PDIA5 ATP5I TSTA3 RPS27L GOLPH3 ARPC5L CTSE ATP8B1 PIK3R2 CTBP2 LYZ GRTP1 ARSD GPATCH4 ELL2 TNPO1 EPHB4 CISD3 NME7	0	DOWN
WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN	GAS1 ZFPM2 REEP1 FGF13 FERMT2 TIMP3 DPYSL3 CAP2 FLRT2 DDR2 ARMCX1 MYH10 SULF1 CAV1 AP1S2 HTRA1 SDC2 RUNX1T1 EFEMP1 WASF3 PMP22 CALD1 SLIT2 IGFBP6 GPNMB FZD7 FLNC DFNA5 PNMAL1 PKD2 RBMS1 FBXL7 BNC2 HBB GPRASP1 DCN LAMA4 PRNP SPOCK2 TCEAL1 TIAM1 CPE RGL1 BASP1 SH3BP5 OLFML1 TMEM45A SIRPA CSGALNACT2 IFI16 SPRY1 C1S ZNF532 PSIP1 HDAC4 CTSK DSE EXTL2 BEX4 TTC28 TCF4 PROS1 PRPS1 CPVL RAB11FIP2 KPNA5 GLI3 CELF2 DAB2 MNDA CLIP4 NDN DPYD CRYBG3 PTGS1 PDGFC NELL2 ANP32E NR2F1 ACSS3 MAF RAB11FIP3 REC8 DOK5 BNIP2 RBFOX2 PTPN12 TMX4 FAM13B MAP3K8 PLSCR3 S100PBP TGFB2 WT1 PRKAR1A HNRNPD DCBLD2 ST7L KDR NUCKS1 DDX5 FER CDON OSTM1 EPB41L5 CRIM1 XPO1 TAOK1 NFIB HSP90AB1 PROCR FRAS1 ST13 WRB ZNF652 UFSP2 NKX3-1 ARNT KAT2B COL8A1 MCOLN3 TSPYL1 ANKRD10 ADH5 RNF146 FBXO21 CERK EFHC1 SEC11A PREPL SOCS5 C11orf80 C6orf62 CANX IFT52 ZNF330 PTPN21 AASDHPPT PPP2R5E PLSCR4 ATF1 SOD2 WDFY3 SLC30A4 GABPA GCA TOB1 WNT5A PDGFD LGALS8 RCHY1 PLA2G12A UGP2 ATP2B1 LXN KIF1B CBR4 SPAG9	0	UP
WONG_ENDMETRIUM_CANCER_DN	OGN PEG3 LMOD1 OSR2 SRPX FLRT2 P2RY14 COL14A1 ECM2 ZEB1 NID1 VGLL3 CXCL12 LDB2 TRPC1 RUNX1T1 COX7A1 EFEMP1 RAMP1 ADAMTS5 IGFBP6 DPP6 SLC24A3 GLT8D2 DCN FBN1 CRISPLD2 EMILIN1 OLFM1 EHD2 ATP8A2 CD248 EFS TRO F10 PAK3 SFRP4 NDN HIC1 LTBP4 MME COL3A1 PAPPA HGF ALDH1A2 SIN3B FOXL2 WT1 MASP1 WNT4 RORB GNLY GAS6 CTSW SLC18A2 PDGFRA TBX3 EDNRB XYLT1 PARM1 PID1 KLRC2	0	UP
WONG_MITOCHONDRIA_GENE_MODULE	GPD2 HMGCS2 ACADSB SLC9A2 NQO1 AGMAT SLC16A5 AUH WARS2 PCCB GSR PCK2 SUCLA2 MRPL13 SLC25A1 HCCS AIFM1 GSTZ1 MIPEP ACAT1 MCCC2 DECR1 ECI1 AK2 MRPS28 ALDH6A1 PDK3 SDHB ATP13A3 COX5A MAOA PDHX NDUFS2 SCO2 MCAT MRPS30 TSPO MRPS16 DLD ECHS1 ATP5G3 CYC1 ATP6V1D MRPL42 NDUFA10 MRPS33 SUCLG1 CPT1A NDUFA9 NDUFS4 NDUFB3 ATP8A1 PPIF NDUFS3 ATP5B PDHA1 UQCRFS1 FH TIMM13 NFS1 ATP5G1 COX5B UNG SCP2 ATP1B1 NDUFV1 NDUFA8 NDUFB6 NDUFC2 MRPL12 SEC61G MRPS18B NDUFA6 MTX2 ATP5F1 UQCRQ CRYZL1 LRPPRC SOD2 ATP1B3 NDUFC1 CYB5A CYP27A1 COX6A1 NDUFB5 ATP6V1C1 COX7B MRPS18A ATP5C1 NDUFB2 ATP5J2 COX7A2 NDUFAF1 MRPS17 NDUFA5 FDXR NDUFA7 GCDH GLUD1 UQCR10 SLC16A3 TUFM NDUFAB1 COX8A COX6B1 NDUFS6 UQCR11 MRPL11 VDAC2 COX6C ATP5O ATP5J ATP6AP1 IDH2 ATP5H NDUFA1 NIPSNAP1 CRYZ SURF1 MRPL49 SLC25A17 COX11 NDUFV2 TIMM10 PTRH2 COQ3 TFAM C21orf33 COX4I1 TIMM8B NDUFB4 DIABLO COX7C MRPL18 ATP5L NDUFB1 GOT2 MRPL3 MRPS15 MRPS18C NDUFS5 ATP5I NDUFB8 COX17 FIBP NDUFS8 TSFM CRAT NDUFA3 DAP3 HSD17B10 PDHB COX7A2L GSTO1 VDAC3 KARS GCAT ATP6V1E1 ATP5G2 CLPP MRPL40 LONP1 TIMM23 UQCRB TOMM40 ATP5E DCTN6 TRIM45 SLC25A22 NDUFA4 ATP6V1G1 ABCB6 TIMM17B DUT HAX1 ATOX1 MTRR GPX4 BOP1 SLC9A5 TOMM7 ATP6V1F ATP6V1B1 DBT SLC25A32 OXCT1 NT5M MTHFD2 BCL2 GIMAP5 PDP1 CP NME4 COX7A1	0	DOWN
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16	SRPX CNN1 AOC3 TFPI PTGER3 FEZ1 PRKCDBP PCDH7 GPX7 ANXA6 PYGM FBN1 COL6A3 COL4A1 PDLIM7 COL1A1 NME4 PCOLCE COL6A2 COL1A2 SPARC ACTC1 SH3BGR TMEM45A ACTN1 COL4A2 DBN1 CRABP1 COL6A1 BGN FADS1 DMPK PRAF2 COL18A1 CRTAP DAB2 NPTX2 TUBB4A TNNT2 COL3A1 NPDC1 MFAP2 NDP SARDH TNNI2 STRA6 REXO2 BCL7C VCAN TP53 PFN2 AQP4 SQLE CD2BP2 FEZ2 CALM3 ADAM15 GAPDH BZW2 KDELR3 GUSB IDI1 FABP5 MSMO1 MAOA CYP51A1 MEST AGR2	0	UP
ZHU_CMV_24_HR_DN	GAS1 TPM2 TAGLN PTGIS THBS2 TIMP3 IGFBP5 DDR2 IGF2 MN1 TGFBR3 ANXA1 ACTA2 FLNA CXCL12 CFD EFEMP1 CYP1B1 LAMB2 MITF COL5A2 LAMA4 C1R LAMC1 COL15A1 CHN1 MYLK COL1A1 COL6A2 COL1A2 PTPN13 TSPAN4 NR3C1 HIVEP2 CDH11 CCND1 BCL2 NFIC SERPINE1 CNN2 SGCG IGFBP3 EPO COL3A1 LDLR TPM1 CRHBP AHR TPM4 FST MATK RAB13 TNNI3 XPC FKBP10 TFAP4 VCAN GPX1 WEE1 MBL2 TNFRSF1A PABPC1 ABL1 ID2 F7 ACTG1 CD151 PDGFRA PYCR1 FAM46A FTL IGF1R UBL4A PAFAH1B1 TRAM2 RUNX1 THBS1 SERPINB6 SULT1E1 ADM LOX AKR1C1 ACO1 POSTN ADRA2A TSPAN6 ANPEP HSD17B2	0	UP
ZHU_CMV_ALL_DN	GAS1 TPM2 TAGLN PTGIS THBS2 ADH1B TIMP3 IGFBP5 TFPI DDR2 IGF2 MN1 TGFBR3 ANXA1 FBLN1 ACTA2 FLNA FGF7 CXCL12 CFD EFEMP1 CYP1B1 LAMB2 MITF RBMS1 COL5A2 LAMA4 CFHR1 C1R LAMC1 COL15A1 CHN1 MYLK COL1A1 COL6A2 COL1A2 PTPN13 TSPAN4 ENG DDIT4 NR3C1 HIVEP2 CEBPD NR2F2 CDH11 CCND1 ZFP36L1 BCL2 NFIC SERPINE1 CNN2 CDC25B SGCG IL6ST IGFBP3 EPO COL3A1 LDLR TPM1 AR APOE CRHBP AHR AARS RALGDS TPM4 FST MATK RAB13 TNNI3 USP4 XPC FKBP10 TFAP2A TFAP4 VCAN GPX1 TP53BP1 WEE1 MBL2 LMNA TNFRSF1A ITSN1 ANAPC1 ERCC5 PABPC1 ABL1 ID2 BMP4 F7 MYH9 ACTG1 CD151 PDGFRA PYCR1 FAM46A FTL IGF1R ANP32A UBL4A PAFAH1B1 TRAM2 RUNX1 THBS1 SERPINB6 SULT1E1 ADM MAPK14 TCF7L2 LOX MARCKS AKR1C1 ACVR2A ACO1 IGFBP2 POSTN MMP1 HNMT ADRA2A TSPAN6 ANPEP HSD17B2	0	UP
BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN	EMP3 WIPF1 TGM2 RAB31 IL10RA LAPTM5 SIRPA IFI16 ARL4C ARHGDIB IFI44 CLEC2B HLA-DPA1 ICAM1 CELF2 DAB2 HLA-DPB1 S100A11 HMGN3 PTGER4 BCL3 STAT1 CYBA PELI1 EZR SEL1L3	1.97554e-05	UP
KEGG_FATTY_ACID_METABOLISM	EHHADH ADH1C ACADSB ACOX1 ADH6 CPT2 HADH ACAA2 ACADS ALDH7A1 ACADM ACAT1 ECI2 ADH1A ECI1 ACSL5 ACAA1 HADHA ECHS1 CPT1A ALDH3A2 HADHB ACOX3 ALDH2 ACAT2 GCDH ACSL3 ALDH9A1 ACADVL ACSL1 CPT1B ADH5 ALDH1B1 ADH7 CYP4A11 ACADL ACSL6 ACSL4 ADH1B	2.8562e-05	DOWN
WOO_LIVER_CANCER_RECURRENCE_DN	ACADSB SULT1B1 CYP4F2 ADH6 CRYL1 CYP2J2 CYP4F3 EPHX2 CYP2C9 SLC35A2 PCK2 PCTP G6PC C4BPA ACY1 TTPA ALAS1 HGD FMO4 BPHL NHEJ1 SLC25A15 APOL6 ECI1 ACSL5 DCXR ACAA1 GLUD2 POR ECHS1 GPT ALDH3A2 ALDH1L1 PPARA CAT HSD17B4 PC CYP3A43 SUOX C4BPB CYB5A CYP27A1 CYP4F12 DAO GCDH GLUD1 PCYT2 SLC2A9 QDPR GOT2 EPHX1 CRAT ACOX2 ADH5 MAT1A PAH HNF4A CSAD SULT2A1 CYP2E1 APOC3 HPD AASS CPS1 MTTP PEMT GLUL PAOX SARDH CA14 MASP2 CA5A SLC2A2 APOC4 LDLR PIPOX PLIN1 SERPING1 ADH1B	2.95141e-05	DOWN
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP	EHF ESRP1 ITGB6 AKR1B10 C1orf116 RAB25 TMEM30B S100A14 PDZK1IP1 CBLC PRR15L FGFBP1 OVOL2 ELMO3 MBNL3 CDS1 F11R OVOL1 CDH1 IRF6 SERPINB5 KCNK1 GRHL2 PKP3 FXYD3 LIMK2 PRSS8 SPINT2 SPINT1 LAD1 SH3YL1 AIM1 PRRG4 ST14 SLPI ESRP2 BSPRY CD24 RNF43 SCNN1A SLC11A2 ELF3 LITAF HOOK2 LCN2 EPN3 ATP1A1 COX5B WDR61 ELF1 TMEM134 TMEM87A BLNK EPHA1 ITPA MUC1 RNF39 SSH3 APRT S100P ACSL1 TACSTD2 SETD6 EPB41L4A RBL2 RHOD DSG3 CLCA2 KRT5 TRIM29 KRT15 GJB3 ZNF165 KLK6 CCNL1 SH2D3A ENTPD2 KRT16 CDH3 KLK5 MAF GSN KIAA0040 PTPN6 STEAP4 PPL ZFP36 S100A8 SERPINA3 TSC22D3 FOSB	3.05318e-05	DOWN
REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE	BSG SLC16A1 SUCLA2 SUCLG2 IDH1 DLAT IDH3A PDK3 SDHB SDHC PDHX SDHD MDH2 DLD SUCLG1 ACO2 SDHA PDHA1 FH NNT PDK2 DLST IDH3B IDH3G CS SLC16A3 LDHA PDK1 IDH2 PDPR L2HGDH PDHB OGDH PDK4 SLC16A8 LDHB PDP1	3.16222e-05	DOWN
KEGG_DRUG_METABOLISM_CYTOCHROME_P450	UGT2B17 UGT1A8 UGT2A3 CYP2B6 UGT1A3 UGT2B15 UGT1A6 UGT1A1 ADH1C FMO5 UGT1A9 CYP2C18 ADH6 GSTM4 GSTA2 CYP2C9 FMO4 GSTZ1 ADH1A UGT2B28 MAOA MGST3 MGST2 GSTK1 CYP3A5 CYP3A43 CYP2D6 CYP3A4 CYP3A7 UGT2B4 ALDH3A1 CYP2C8 ALDH3B2 GSTP1 GSTO1 GSTM1 ADH5 ADH7 CYP2A7 GSTM2 CYP2C19 GSTA3 ALDH3B1 CYP2E1 UGT2A1 CYP2A6 GSTA4 CYP1A2 FMO3 GSTM3 GSTT1 CYP2A13 GSTA1 GSTT2 AOX1 ALDH1A3 FMO1 FMO2 GSTM5 MAOB ADH1B	3.27934e-05	DOWN
KEGG_CITRATE_CYCLE_TCA_CYCLE	PCK1 PCK2 SUCLA2 SUCLG2 IDH1 DLAT IDH3A SDHB SDHC SDHD ACO1 MDH2 DLD SUCLG1 ACO2 SDHA PDHA1 FH PC DLST IDH3B IDH3G CS IDH2 MDH1 PDHA2 PDHB OGDH ACLY OGDHL	3.40547e-05	DOWN
MOOTHA_VOXPHOS	NDUFS1 TMCO6 SDHB SDHC COX5A SDHD NDUFS2 NDUFB7 ATP5G3 CYC1 NDUFA10 NDUFA9 NDUFS4 SDHA NDUFB3 ATP5D NDUFS3 ATP5B NDUFS7 UQCRFS1 UQCRC1 UQCRC2 ATP5G1 CYCS COX5B COX10 NDUFA8 NDUFB6 NDUFC2 COX15 NDUFA6 ATP5F1 UQCRQ NDUFC1 CYB5A COX6A1 NDUFB5 COX7B ATP5C1 NDUFB2 ATP5J2 COX7A2 NDUFA5 NDUFA7 UQCR10 NDUFAB1 COX8A COX6B1 NDUFS6 NDUFA2 UQCR11 COX6C ATP5O ATP5J ATP5H NDUFA1 SURF1 COX11 UQCRH COX4I1 NDUFB4 COX7C ATP5L NDUFB1 ATP5I NDUFA13 NDUFB8 BCS1L NDUFS8 BCL2L1 NDUFA3 COX7A2L CNOT7 ATP5G2 UQCRB ATP5E NDUFA4 TBCB MBD3 COX6A2 SURF2 TONSL NDUFA4L2 COX7A1	3.54169e-05	DOWN
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP	PBK ASPM ECT2 E2F8 MAD2L1 MAPK13 PRC1 KIF4A LRRC1 MARCH3 TTF2 TTK MEP1A NEK2 KIF11 CCNA2 CEP55 AURKA HK2 CCNB1 DLGAP5 OIP5 GALNT7 TOP2A DTL KIF20A ZWINT CDC20 RAD51AP1 CCNB2 HN1 MKI67 FOXM1 TPX2 SOX9 GPD1L MTMR2 TMED3 CD24 PLBD1 DDR1 TNFRSF21 CDC6 EZH2 BACE2 NDC80 B4GALT5 BUB1B ELF4 MECOM CENPF HELLS KIF18B CDC7 ATP1A1 DEPDC1 FBXO5 CDKN3 ASRGL1 CENPE PRKCD KIF23 LMNB1 SOX4 NUSAP1 MARCKS KIF2C SYNJ2 RACGAP1 SKA1 TMEM51 MCM2 CDK1 SLC16A3 SMC4 SEL1L3 KIF14 NCAPG BIRC5 UBE2C PELI1 PLP2 CYBA AURKB PTTG1 SLC38A1 CKAP4 LHFPL2 SLC12A3 HJURP G6PD HIST1H4C S100P FANCI ORC6 PAFAH1B3 HDAC2 SLC1A5 TUBA4A HMGB2 NCK2 UGCG FEN1 FAM118A MARCKSL1 AFP PDE9A MMP12 LAMB1 CTBP2 WSB1 ARID3A DSCC1 SLC7A7 BCAT1 CCNE1 TRIP13 ABCC1 IGF2BP3 PRR11 ETV4 SLAMF8 RFC4 SPHK1 BARD1 DUSP9 PTP4A3 MMD SHCBP1 DBN1 NT5DC2 ZNF532 SALL2 PNMA1 VEGFB CHST11 WASF1 MMP9 FHOD3	3.68926e-05	DOWN
SWEET_KRAS_TARGETS_UP	MYL9 TAGLN FERMT2 TIMP3 TNS1 FLRT2 CCL2 C8orf4 SPOCK1 CALD1 DKK3 DFNA5 ATP2B4 ADAM19 BHLHE40 CADM1 LBH WIPF1 JUN COL4A1 COL1A1 NUAK1 SLC16A4 JUNB EVL IGFBP7 SPARC NPTX1 C1S COL4A2 WISP2 PALLD NCF2 GLIPR1 SERPINE2 ADCY7 CHST3 NLRP1 SNAI1 COL5A1 HSPG2 PMEPA1 MSC SERPINE1 MATN2 COL7A1 ST5 TGFBI GABARAPL1 IGFBP3 TPM1 ULK1 SGK1 MAP3K8 HSPB1 TGFB2 JAK1 ECE1 CDH4 GADD45B DICER1 NCK2 MGEA5 BMP1 ITGAV DNAJB2 EPHB2 CCDC53 PGLS SOX4 RSU1 P4HA2 PDXK ACVR1B INPP4B CLDN4 HGD TUFT1 LAMP2 SLC22A5	3.80998e-05	UP
REACTOME_PHASE_II_CONJUGATION	UGT2B17 UGT1A8 UGT1A3 UGT1A6 UGT1A1 UGT1A9 NAT2 SULT1B1 GSTM4 NAT1 GCLM GSTA2 UGDH PAPSS2 SLC35D1 SULT1A2 AHCY TPMT UGT2B28 SULT1A1 MGST3 UGP2 MGST2 GSS GGCT SULT1A3 CNDP2 GCLC SULT1E1 UGT2B4 GGT1 SULT1C4 MAT2B OPLAH ACSM1 GSTP1 GSTO1 GSTM1 MAT1A BPNT1 MAT2A SULT2A1 GSTA3 GLYAT COMT UGT2A1 SULT2B1 ACSM2B GSTA4 CYP1A2 SULT4A1 PAPSS1 GSTA1 MTR GGT5 SULT1C2 GSTM5 NNMT	3.84966e-05	DOWN
YU_MYC_TARGETS_DN	CD37 KLF2 PYGM RBMS1 MS4A1 IL10RA OLFM1 HLA-DOB EVL PTPRC LAPTM5 HLA-DQB1 HLA-DQA1 LTB SSPN BLK CTSH HLA-DMA CD2 PRKCB MACF1 LIFR HLA-DRB1 RGL2 HLA-DMB CD74 MAP4K2 SRPK3 SIPA1 GGA2 GDI1 MYO7A ARHGEF1 SPIB CD1D ACP5 BTG1 ARID3B ABCA1 UNC93B1 RAG1 DGKA GAD1 GNS KLF3	3.87925e-05	UP
MOOTHA_FFA_OXYDATION	ACADSB AMACR CPT2 HADH ACAA2 ACADS ACADM ACAT1 DECR1 ECI1 HADHA ECHS1 CPT1A HADHB ACADVL CRAT ACSL1 HSD17B10 NBN ACADL LMF2 NCAPH2	4.02465e-05	DOWN
ABE_VEGFA_TARGETS_30MIN	CYR61 EGR1 PTGS2 TAC1 EGR3 ELAVL4 NR4A1 EGR2 HBEGF SCRN1 GZMK PCDH17 TRIB1 AURKC DUSP5 HDC MYO7A APOE C2 CD1B MPG PPY TKTL1 VARS MCM2 ALAD RCAN1 KRAS	5.1619e-05	UP
RODWELL_AGING_KIDNEY_NO_BLOOD_UP	RGS1 TAGLN C7 TFPI CCL2 NNMT TNC ZCCHC24 COL14A1 PTRF LHFP ZEB2 ANXA1 LOXL1 SERPING1 AXL LTF FN1 FHL1 VEGFC CDO1 GPNMB ISLR MOXD1 DKK3 C3 AEBP1 MCAM RFTN1 KCND3 FBN1 C1R COL15A1 VCAM1 COL6A3 SPARCL1 CHRNA3 COL1A1 NUAK1 RBMS3 COL1A2 C1QA CXCL2 DEGS1 PAM C1S OSMR CDH6 TIMP1 TPSB2 LUM MRC1 FSCN1 PELO SERPINE2 DRAM1 PHLDA3 GGT5 MAP4 SLC1A3 CALU MFGE8 C1QB A2M CDH11 SOCS3 VASH2 COL5A1 MRAS RBP1 NOV PDGFC SERPINH1 HOMER3 NR2F1 STAB1 INHBA COL3A1 HGF TPM1 GGA2 MMP7 GFRA1 PXDN ZMAT3 SPTLC3 PLK2 TIMP2 PRB1 WFDC2 B3GAT3 PAPPA2 SCN5A AIDA RPS25 SYMPK RPL35A MICALL2 TBCB AATF ARHGAP1 RPL35 KIRREL STS RPL12 RPL27 ASNS MMP11 MSR1 GABRP RAD54L ANTXR1 BHLHE41 RPS10 DLGAP1 ABI3BP PPP1R14B MYOF SSR4 CRELD2 VTCN1 MIOS PLOD3 FEZ2 UBE2Z NFIX C1orf186 CDC42EP1 TRIL LEPROT POLR1D RPS27L CLDN1 RPN2 VARS CXCL14 PCDHA9 RPN1 CKAP4 TPBG P4HB AMBP CFB SMPD2 ANXA2 CXCL6 ITPR3 PDIA4 HEXB MGLL VSNL1 TNFRSF11B ITM2C CLDN3 CYFIP1 SPON1 TMED3 ABCC3 DPP3 SLC46A3 TSPAN1 ADRA2A SYTL2 TMPRSS4 SOAT1 PIGR RARRES1 PROM1 ITGB6 OCLN	5.24653e-05	UP
WOO_LIVER_CANCER_RECURRENCE_UP	MGP CTGF MAB21L2 RGS1 TPM2 CRYAB GEM DPYSL3 ENO2 CCL2 CSGALNACT1 RGS2 ZEB2 EPHA3 FLNA PMP22 SLIT2 LPCAT1 TGFB1 LAMA4 DPYSL2 LAMP3 COL6A3 GAS7 COL1A1 FGFR1 EVL RGS10 COL1A2 VEGFB DBN1 LAMA5 JAG2 DAB2 CXCL1 PPT1 MAPK12 DUSP4 BCL2 MEF2C ENPP2 IGFBP3 PFKM CCND2 CCNI MICAL1 PLAU NOTCH2 TGFB2 TPM4 ZNF354A CCND3 DDIT3 ARHGEF2 COL9A2 SOCS1 FZD1 PLAUR GPC4 COL11A1 TNFRSF25 BHLHE41 PFKP UBR5 PFN2 PTMA TEAD4 QSOX1 E2F3 SGCB TACSTD2 TREM2 ARHGAP4 JAG1 TMSB10 EFHC1 PDGFA TLK2 TPBG HMGA1 S100A6 SEMA6A EXT1 ALDOA CRIP1 SEMA3C RHOF CXCL6 LOX TSPAN3 MARCKS PLAGL1 DDR1 FGD6 CD24 SOX9 FGFR2 PLCE1 POSTN MYO6 HK2 HKDC1	5.33397e-05	UP
AMIT_EGF_RESPONSE_40_HELA	EGR1 PTGS2 ATF3 PALMD EGR3 NR4A1 DUSP1 KLF2 PPP1R15A JUN JUNB ZFP36 BTG2 DUSP2 IER3 IL6 IER2 SLC2A3 CEBPB KCNJ12 DUSP5 LDLR SGK1 CBX4 CCNL1 KLF6 MBNL1 PIAS1 MBNL2 RPS11 NFIB UBR5 BCL3 PIP5K1A CCNA1 UBE4B ID1 CAMKMT CDKN2AIP HES1 RNF141 SEC23A	5.42437e-05	UP
NIELSEN_LEIOMYOSARCOMA_CNN1_UP	MYL9 KCNMB1 LMOD1 CNN1 TAGLN MYH11 ACTA2 PPP1R12B RAB23 SORBS1 MYLK SVIL GABRG2 TFPI2 RIMS2 ALDH1B1 TRDMT1 LOC81691 LAMA3	5.5179e-05	UP
REACTOME_GLUCURONIDATION	UGT2B17 UGT1A8 UGT1A3 UGT1A6 UGT1A1 UGT1A9 UGDH SLC35D1 UGT2B28 UGP2 UGT2B4 UGT2A1	5.53389e-05	DOWN
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN	FOSB CHRDL1 ATP1A2 LMOD1 FABP4 TAC1 ADIPOQ AOC3 CASQ2 ADH1B PALMD SFRP1 PTGER3 CES1 APOD PPP1R1A CFD CLEC3B ITIH5 LPL SEMA3G G0S2 GPX3 SLC24A3 ANGPT1 MAOB PLA2G16 FZD4 SVEP1 PLIN1 IGF1 ABCA8 ASPA IFI44L RBP4 BST2 CLDN5 RAPGEF3 SLC7A10 DUSP4 ANGPTL4 CETP GYG2 FAM149A LIPE NPR1 GPC3 NTRK2 TIMP4 TFPI2 ACACB GPD1 CD36 PDK4 PLA2G2A PTX3 METTL7A AQP7 NPY1R VIPR1 AKR1C1 C1orf115 TNMD PPP2R1B AKR1C2 MAOA SELENBP1 CA4 CEBPA MEST AGT PCK1 ABCC6 PPARG AKR1C3 ADH1C	5.6147e-05	UP
BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN	CYR61 CTGF ACTG2 TAGLN TNC IGF2 FHL1 PBX3 SORBS1 THY1 ALCAM DUSP6 MYC SERPINE1 INHBA ACTA1 PTGER4 FEZ2 TMSB4X CBX1 CINP THBS1 ACTN4 ADM LY75	6.46542e-05	UP
IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN	ASPN CRYAB PTGIS AKAP12 MFAP5 PALMD ARHGAP29 MYH10 MYH11 FBLN1 SERPING1 SORBS2 FZD7 MFAP4 ATP2B4 COL5A2 SLC24A3 LAMA4 KCNE4 JAM2 FBN1 GPRC5B NUAK1 EHBP1 NPR3 LRRC17 SLC29A1 IGF1 HSPA2 CA11 RGS4 TPD52L1 TCF4 GATA3 SST ZSCAN18 RTN2 LTBP2 CELF2 DAB2 CDH11 NDN BCL7A AR N4BP2L1 VCL LZTFL1 DAAM1 LOXL2 NEK1 IGF2BP3 PBX1 HYAL1 STAT4 TXNIP NFIB TNNC1 LAMB1 RASAL2 FGF21 EN1 TLE1 PIP5K1A PPP4R4 MYH2 DHRS3 DHX40 CFB ID1 GPR87 NRIP1 PRKAG2 ASAP3 LOX KDM5B SMAD1 PRKCI AKR1C1 CISD1 SLPI AKR1C2 PCSK6 CA12 POSTN PLOD2 SYTL2 MEST EPB41L4B ANXA3 HOXB6	6.56488e-05	UP
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN	SCG2 ZCCHC24 ZEB1 MAP1B KLF2 FLNC SEMA3A TUBB2A GFPT2 PNMA2 NUAK1 FZD2 GNG11 COL6A2 APLP1 ARNT2 GRB10 TTC28 GRK5 AK5 SH2B3 BDNF KIF3C UTRN EDIL3 LOXL2 IL11 CD99 BCAT1 ADAMTS12 MMP16 DPY19L1 RGS7 PFKP SHOX2 ARHGAP17 TRAF3 TRIO GULP1 TNIP1 FAM171A1 ARHGEF40	6.66746e-05	UP
GENTLES_LEUKEMIC_STEM_CELL_UP	VNN1 GUCY1A3 HLF MMRN1 RBPMS SETBP1 HOPX EVI2A SH3BP5 LTB GIMAP6 ICAM1 CD34 MEF2C BIRC3 ABCC2 LGALSL PCDHGA10 FBXO21 HECA SLC38A1	6.77329e-05	UP
VANDESLUIS_COMMD1_TARGETS_GROUP_3_DN	UCHL1 PCP4 FEZ1 RGS2 MEOX2 MFAP4 WFDC1 VCAM1 TUBB2A CP CRABP1 TRIM9 NNAT CRABP2 MSLN TCF15 NR2F1 TGFBI SCG3 MFAP2 TUBB3 CLEC1B DLL3 CCDC94 VTN TMSB4X HOXD12 EN2	7.40829e-05	UP
REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	CCL2 CCL21 CXCR4 CXCL13 CCL11 CXCL12 CCL19 CCR7 CCL3 CXCL2 CX3CL1 CCL22 CCR10 CCR6 CCL4 CX3CR1 PPBP CXCR5 CXCL1 CCR1 CCR2 CCL20 CCR4 CCL17 CXCR2 CCR5 XCR1 CCL27 XCL2 CCL25 CXCR6 CCR9 CCL16 CXCL9 CXCR3 CXCL3 XCL1 CCL5 CXCL10 CCR3 CCR8 CCL7 CXCL5 CXCR1 PF4 CXCL11 CXCL6	7.51263e-05	UP
CROONQUIST_NRAS_SIGNALING_DN	GNAI1 CENPA KIF11 CCNA2 CDC25C AURKA CCNB1 PLOD2 OIP5 GINS1 GALE TOP2A ZWINT CHEK1 STIL CDC20 CCNB2 MKI67 FOXM1 TPX2 SPC25 CDC6 NDC80 BUB1B CKS1B SMC2 CDKN3 PLK4 LMNB1 KIF2C KIAA0101 KIF22 MCM4 EIF5 MCM2 CDK1 SMC4 CHEK2 TK1 NCAPH SNRPA1 UBE2C HMGA1 SPAG5 AURKB PTTG1 BRD8 RFC3 PCNA H2AFX TRAIP POLD3 MCM7 HMGB2 PLK1 WEE1 EXO1 DUT POLD1 CSE1L CHAF1A STMN1 NASP TRIP13 MCM3 APOBEC3C SBNO2 MYBL2 RFC4 PTP4A3 RAD51C FADS3	7.58934e-05	DOWN
HOELZEL_NF1_TARGETS_DN	ADAMTS1 SCGN C7 IGFBP5 GREM2 TSPYL5 FBLN1 FN1 LEPR ADAMTS5 PRKD1 DCHS1 FSTL1 FBXL7 ST8SIA1 SERPINF1 TMEM204 CP CD200 SNAP91 BGN ZNF423 GATA3 ST6GALNAC5 GFRA2 NR2F2 AMPH AK5 ST8SIA2 MATN2 NR2F1 BCL11A COL3A1 CHST7 BDNF WWOX GRM7 SATB1 HDAC9 NTRK3 FRMD4A MFAP2 C2orf68 TES HAUS5 DLX6 AASS MMP16 NECAB2 HRK WDR59 LONP2 PDK4 ADCY1 FOXO3 RLN2 ZNF395 PDGFRA SSTR2 CUX1 PDPR ARHGAP28 ADM EDNRB TGIF1 WNT5A DNAJC15 CD24 PLEKHA6 SLC39A8	7.61995e-05	UP
BASSO_CD40_SIGNALING_UP	RGS1 CR2 BCL2A1 GPR183 SNN NEFM CCR7 LGALS1 CCL3 JUNB HTR3A LAPTM5 TNFAIP2 NCKAP1L HLA-DQB1 DUSP2 ARID5B TNFAIP8 PLXNC1 CCL22 HLA-DQA1 LRRC32 NCF2 PIK3CD DDIT4 HLA-DMA CD83 PHACTR1 ICAM1 SRGN RAC2 IER3 CCL4 CXCR5 HLA-DRB4 CD44 PLEK HLA-DPB1 ZFP36L1 CD40 CD74 TNFAIP3 BCL2 PTP4A3 IRF5 MEF2C BATF STAT5A SH2B3 TCFL5 TMC6 IRF4 NFKBIA LYN MAP3K8 EHD1 TRAF1 ADAM8 IL1B RNF115 LTA ARHGEF2 TNFSF9 SLAMF1 STK10 MAPKAPK2 ELL2 NFKB2 IFI30 UNC119 NFKBIE VOPP1 GADD45B PTK2B ICOSLG TCEB3 IRF9 TRIP10 KCNN4 KRT7 STAT1 HSP90B1 CFLAR SYNGR2 TMSB4X DTX2 LHFPL2 TAP1 HLA-F MTMR4 RAB27A PTPRE TNF RXRA CAPG CHD1 CD58 LITAF MYB	7.73039e-05	UP
REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE	SUCLA2 SUCLG2 IDH3A SDHB SDHC SDHD MDH2 DLD SUCLG1 ACO2 SDHA FH NNT DLST IDH3B IDH3G CS IDH2 OGDH	7.81255e-05	DOWN
TIAN_TNF_SIGNALING_NOT_VIA_NFKB	FOSB EGR1 NR4A1 PPP1R15A PDE8B JUN MAFF FZD2 JUNB DUSP2 RGS16 GATA2 IER3 KLF10 PTGES MNT KLF6 INSIG1 TIPARP HSPA1A EXT1	7.84407e-05	UP
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP	CTGF TIMP3 CLU CCL2 TNC ACTA2 NCAM1 MPDZ FN1 CYP1B1 FBLN2 COL5A2 JUN COL4A1 COL1A1 IGFBP7 COL4A2 TIMP1 TGFB3 PROS1 COL18A1 GATA2 INHBB MAP4 CDH2 SNAI1 SERPINE1 NR2F1 INHBA COL3A1 ODC1 CSF1 PLA2G4A RBL1 MCM3 DCK FURIN RBBP6 PKP1 SMARCD1 GADD45B CHRNB1 ITGB1 HMGB1 GLG1 IL4R CCL7 ZFX RPSA CCT6A TPP2 PDGFA TOP1 TRAF3 PAFAH1B1 OAT S100A6 BRCA1 PPIC SMAD1 PLK4 EDN1 LY75 MKI67 CHEK1 CENPA	7.96115e-05	UP
GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN	APOBEC3B GGH XK AMMECR1 MAD2L1 KIF15 PRC1 GMNN KIF11 MINPP1 CCNA2 CEP55 MELK DLGAP5 OIP5 GINS1 TOP2A DTL ZWINT CHEK1 CDC20 RAD51AP1 CCNB2 DHFR ATP5G3 CDC6 NDC80 BUB1B PPIF FABP5 KIF18B CKS1B SMC2 CDKN3 NUSAP1 KIF2C RACGAP1 CCNE2 RNASEH2A KIAA0101 GINS2 MCM4 SAC3D1 MCM2 CDK1 TYMS TK1 NUP85 NCAPG BIRC5 POLE2 RFC3 PCNA MSH2 CENPM RRM1 BUB1 RRM2 HAT1 VDAC3 SNRNP25 VRK1 FEN1 GZMB MCM10 CDC45 MCM6 DSCC1 MCM5 DUT CSE1L CD36 CCNE1 TRIP13 AQP3 PRG2 CDC25A NPM3 HBD CPA3 RFC4 SLC7A5 CSF2RB HBB LEPR	8.0493e-05	DOWN
GERHOLD_ADIPOGENESIS_DN	CYR61 GAS1 CTGF CRYAB THBS2 CCL2 THBD FGF7 CXCL12 FN1 TUBA1A G0S2 GAS7 CD81 TNFAIP2 ANXA5 PDGFRB UCP2 IER3 CEBPD IL11RA SAMHD1 AKR1B1 CCND1 CD44 TUBB CCND2 HGFAC UBTF ECM1 SAE1 MMP14 ZNF148 CDK4 GAS6 VCAN ITGB1 EEF2 IL1R1 IL4R CCT2 CCL7 CDC37 DDB1 EIF3C HSPA8 BID PLAT CCT5 PDCD2 THBS1 DNAJB1 ATF1 CASP8 IFRD1 ANXA2 BAX SOX4 CD9 VDR XDH SDC1 ANXA3	8.31268e-05	UP
PLASARI_TGFB1_TARGETS_10HR_DN	ADAMTS1 OGN GAS1 PEG3 MEIS2 SDPR IGFBP5 PALMD THBD SYT11 PPP1R3C TGFBR3 FGF7 LDB2 RUNX1T1 CAND2 CYP1B1 PMP22 DCLK1 ADAMTS5 PCDH7 THSD7A PCDH9 LPL DIXDC1 FAT4 STMN2 FBXL7 PDE1A IRS1 TRPS1 SLC24A3 CD93 PER3 PLCB1 LAMA4 PRRX1 SEMA3A SERPINB9 EPHA7 VCAM1 TCEAL1 SLC16A4 EVI2A DZIP1 MPPED2 SH3BP5 ZFHX4 NPR3 IGF1 RASGRP3 PRKAR2B ARID5B ARNT2 LUM AQP1 MRC1 PDP1 CTNNAL1 FOXC1 SCARA3 LIFR PDE5A CELF2 DAB2 SVIL CBX6 CDH2 CLIP4 MSH6 PLEK DBP DIRAS2 TOX ZNF467 MAP2 LRRN3 KCND2 GAMT C3AR1 SH3BGRL WDR19 MEF2C IL6ST PIK3R3 EYA4 RFC4 RARB IFIT1 CENPJ NR1D2 TLE6 KLHL24 PHIP PBX1 ANGPT2 SMARCA2 SERHL2 AGTR2 CYP7B1 ZIC1 SIX1 PIK3R1 STMN1 CD36 GBP1 SIM2 MMP16 EYA1 IL1RN NFIB HOXC10 CDC42EP2 MMP11 AMPD3 RAB30 RCBTB2 GSTM2 PRIM1 PDK4 USP18 ZFAND1 BNIP3L SLC14A1 PDLIM2 EIF2AK2 STAT1 LPAR4 NFIX KITLG SESN1 HERC6 PDGFRA RND3 IFIT3 ZFR SHOX2 ITGB3BP BUB1 EPHX1 GULP1 ARHGAP28 ABLIM1 RFC3 PTEN DHRS3 PTX3 TK1 TRIM37 RTP4 GLRX ADM GAS2 METTL7A EDNRB TRIM21 NMI TCF7L2 AUTS2 MAN1A1 UNC5C PTPRD IFIT2 MARCKS NUSAP1 LMO7 ARL6IP1 CDKN3 MLLT3 REPS2 CD24 FGFR2 SORD RNASEL MKI67 ZWILCH SLC12A2 TRIM2 SERPINB1 ACADM DTL IDH1 CCNB1 ELOVL6 MBNL3 TMEM53 MEST HMMR LGR4 IL18 NQO1 DDC	8.42205e-05	UP
BURTON_ADIPOGENESIS_9	CYR61 FOS EGR1 PTGS2 GEM AKAP12 THBS2 FERMT2 CCL2 ARMCX2 ANXA1 NDRG4 CXCL12 SPG20 SPP1 AMOTL2 VCAM1 DNM1 NME4 FZD2 ASAP1 CSRP1 TSPYL4 HCFC1R1 TPD52L1 FADS1 MAGED2 CEBPD CXCL1 RECK CNN2 TPM1 RASA4 PHLDA1 PLK2 CYTH3 CSF1 PLA2G4A GSTT1 SIRT2 IFI30 DOK1 CDKN2A CDK4 GPC4 SLC8A1 C6orf25 ID2 CCL7 CNN3 RNF13 GSTM1 SNX6 EPHX1 CITED2 PLAT GRN HEBP1 THBS1 F2R TOR1AIP2 GAS2 ROCK2 MFSD1 ID3 DDAH2 KLF4 ANXA11 CDKN2B PRKCD STXBP3 SKAP2 NEDD9 ACVR2A F3 MAOA CTNND1 LGALS9 JUP GALK2 KIFAP3	8.53435e-05	UP
RAMALHO_STEMNESS_DN	MLLT11 NCAM1 MAL EFHD1 NRP1 GAS7 RELN CORO1A EVL EVI2A RGS10 ITGB2 PTPRC CSF1R CMA1 SIRPA LAT2 LY86 TYROBP CD53 PRKCB HSD11B1 CEBPD ST3GAL6 KCNAB2 CYFIP2 HDC ZAP70 BIN1 GSN CBX4 GRINA RGS14 PGLYRP1 ROGDI B4GALNT1 GRIA2 COL11A2 ZDHHC14 NIN STMN1 CD68 SLC11A1 ACVRL1 RBMX CST3 CTSB CD47 CLEC4A BMP1 PPP3CA AP2A2 ABLIM1 RTN3 ABR ARG2 PPP2R5A HSD17B8 CTSS PAPSS2	8.64968e-05	UP
VILIMAS_NOTCH1_TARGETS_UP	EGR1 BCL2A1 EGR2 CD69 NOTCH3 CCR7 IL10RA JUNB THY1 CX3CL1 LCK GATA3 CD2 CD83 NFATC1 TRAT1 ICAM1 CD86 CD3D TOX CD74 ZAP70 CD28 LAT P2RY10 NFKBIA TRAF1 CTLA4 BIRC3 PTCRA NFKB2 CD7 RAG1 IRF7 IL12B CCL5 HEY1 CD80 RAG2 GZMB ID2 RELB CD3G TARP BIRC2 RRAS2 GZMA DDR1	8.76817e-05	UP
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN	VNN1 TCEAL2 GUCY1A3 DMD HLF TFPI CH25H TGFB1I1 RBPMS ARMCX2 CXCL13 CCL19 PCDH9 SELL LIMCH1 HLX CD200 EVI2A SH3BP5 CXCL2 PTPRC IFI16 CREM HLA-DQB1 FNBP1 ANXA5 HLA-DQA1 CLEC2B CYTIP TRIM22 TCF4 GLIPR1 HLA-DPA1 ERG BAALC DUSP6 SVIL CXCL1 HLA-DRB4 CD44 IDS CD40 AREG BCL11A INHBA RABGAP1 ALOX5 TM4SF1 IL18R1 CRHBP ADAM8 IL1B BIRC3 PPFIBP1 GBP2 C3orf14 CXCL3 RPL31 PTGER4 SPTBN1 ADAM28 PMCH HIST2H2BE TRA2A CD59 TNFSF4 TSPAN31 TPBG H1F0 NFAT5 SORL1 OPTN NRIP1 CTSO CXCL11 TCF7L2 SOD2 CCNG2 CXCL6 MLLT3 TNFSF10 ENPP4 TSPAN6 MYO5C HIST1H2AC EMP1 MPZL2 AKR1C3	0.000102823	UP
AMIT_SERUM_RESPONSE_60_MCF10A	CYR61 EGR1 PTGS2 GAS1 CTGF NR4A2 EGR3 TNC RHOB VGLL3 HBEGF FN1 CALD1 KLF7 BHLHE40 EREG TCEAL1 MAGED2 MAFB IER2 TRIB1 CYBRD1 DUSP5 TNFAIP3 CCL20 PNRC1 INHBA SGK1 MAP3K8 TM4SF1 PLK2 ELL2 POT1 MBNL2 PTGER4 ITSN1 PMAIP1 IRS2 PIP5K1A SERPINB13 BMP1 ZC3H12A COBLL1 ETS2 FRMD4B STK38L PDLIM5 TGIF1 PCBD1 RCAN1 SOX4 PXMP4 SCD SLC35D1 TUFT1 C1orf116	0.000104077	UP
CHIBA_RESPONSE_TO_TSA_UP	FOS FOSB CTGF TIMP3 CAV2 ITGA7 HBEGF VEGFC TGFB1 JUNB COL1A2 PECAM1 ARHGDIB LUM SOD3 PDGFRB NGFR CDKN2C MMP19 ANK1 TIMP2 TRIP6 EFNB3 RHOG CD8B RING1 SIVA1 CD36 MMP13 PLA2G6 MMP11 TP53I11 QSOX1 BMP4 KRT7 VTN KRT14 BMP6 ITGA3 APRT CASP9 FASTK HLA-A BAD GLRX CD9 FBN2 JUP IGFBP2 KRT19 BSG	0.000105362	UP
TSAI_RESPONSE_TO_RADIATION_THERAPY	CYR61 EGR1 CTGF IGFBP5 CD69 TGFBR3 VEGFC HBB COL6A3 COL4A1 COL6A2 BST2 COL6A1 IL6 A2M IFI6 TGFBR2 SERPINE1 TGFB2 ISG15 IFITM1 OAS3 TSC22D1 SMAD3 VEGFA PLAT THBS1 CFB IFIT2 TNFRSF11B LGALS3BP LIPC	0.000106679	UP
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP	CYR61 CTGF ZBTB16 CNN1 ATF3 TIMP3 CLU AGTR1 TSC22D3 NID1 FHL1 CALD1 KLF2 MYOT DIXDC1 FLNC MFAP4 DNAJB5 BCL6 PLA2G5 JUN TMEM204 C10orf10 ZFP36 MYOM1 SH3BGR PER1 BTG2 NES DDIT4 FSTL3 ZBTB20 CEBPD CHST3 CEBPB CD163 HYAL2 AREG SERPINE1 CYP4B1 MTHFD2 DOCK9 C9orf3 FKBP5 ACTA1 TCAP SLC38A2 VCL TIMP4 NFKBIA CSDC2 SNAI2 RNF115 KLF9 MAPRE2 MCL1 TXNIP GLUL ZFAND5 CDC37L1 PIK3R1 SLCO4A1 ANKRD2 GADD45B LAMB1 PDK4 FOXO3 SYNPO2L TIPARP ZNF189 IRS2 CDC42EP4 RND3 RERE CCNB1IP1 ANKRD1 MT2A GADD45G REV1 FNDC3B NCKIPSD METTL7A MT1X MT1H AMD1 INSR FOSL2 MT1E IER5 ELF1 MT1F CDKN1A MT1M RRAS2 PLIN2 DDAH1 NFIL3 POSTN KCNK1 XK	0.00010803	UP
TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN	FOS FOSB EGR1 SYNM MGP ATP1A2 TAC1 ACTG2 CNN1 CRYAB TAGLN ATF3 TUBB2B PALMD GPM6B SFRP1 FHOD3 ID4 TNC C8orf4 MYH11 CAV2 PDLIM3 RBPMS APOD ANXA1 ACTA2 LTF CFD SORBS2 DUSP1 ADAMTS5 FZD7 RRAD MAOB MYLK MAFF C10orf10 CP PER1 CX3CL1 CHL1 GATM ALDH1A3 ST3GAL6 PTN AK5 CYB5R2 MEGF6 MAP2 GABRE ZNF667 BBOX1 TFAP2B GPC3 PDZK1 ARMCX4 KIT SCGB1D2 MMP7 FAM189A2 CDH3 TFPI2 TM4SF1 ZNF83 TSHZ2 CLDN11 PI15 KRT16 SEC14L1 CFI TRIP6 ATP10D KLK7 OXTR KRT17 SLC25A37 HOXA3 BCOR KRT15 KRT23 CHI3L1 DST LIN37 TRIM29 SF1 NFIB KRT5 KCNC4 GABRP ITGB8 DSG3 BHLHE41 DSC3 TF MID1 MYBPC1 VTCN1 IQCA1 KRT7 CSNK1A1 KRT14 ULK4 PSME4 RND3 DLG5 SCGB2A2 KRT6B SOCS5 CD59 TNFRSF10B PTPN21 ELF5 NDRG2 PTX3 RAB27A MICAL3 RAPGEF2 ITGB4 EGFR SOD2 RCAN1 CHIC2 ZDHHC3 ELF3 SOX9 MET LAMC2 SERPINA1 CLDN8 TRIM2 STEAP3 LAMA3 CDC14B LAMB3 EDN3 PDZK1IP1 GRAMD3 HOXA9 PIGR RARRES1 ANPEP RNFT1 TGFA HMGCS2 COL17A1 EHF	0.000109415	UP
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN	FOS PTGS2 MGP TNC LOXL1 NID1 CXCL12 CYP1B1 CDO1 C3 LAMA4 VCAM1 ZFP36 OSMR WISP2 COL6A1 PROS1 CRTAP LTBP2 CEBPB CXCL1 ZFP36L2 DPEP1 ADAM23 IL1RL1 IL1R1 PDK4 STAT3 AP3S1 MAGED1 TMEM176A PTX3 TMEM176B RNASE4 CXCL6 LOX FAS DDR1 SLPI FGFR2 SLC12A2 MAN2A1 LXN VDR	0.000125505	UP
ROZANOV_MMP14_TARGETS_SUBSET	TIMP3 FN1 EFEMP1 CALD1 ANGPTL2 LAMA4 COL4A1 COL6A2 COL4A2 COL6A1 COL18A1 PLXND1 NR3C1 COL5A1 PTGS1 CHSY1 SERPINH1 MATN2 MDK HIF1A LAMB1 EMILIN2 PAEP ANKRD1 HAS2 TNFRSF11B PLOD2	0.000126999	UP
CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN	PCOLCE2 LOXL1 SDC2 RDX COL5A2 ROBO1 JAM2 FBN1 COL6A3 PCOLCE COL6A2 COL1A2 LAMA2 TIMP1 COL6A1 BGN LTBP2 CDH11 CXCL1 CDH2 GPC1 COL5A1 LPAR1 COL3A1 LTBP1 FOXC2 VCAN EMILIN2 SYK NT5E SEMA3C CXCL6 LOX SDC1	0.000134882	UP
WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN	CYR61 OGN CTGF ATF3 C7 NR4A1 CAV2 PCOLCE2 OLFML3 RGS2 CAV1 DUSP1 PPP1R15A C3 HBB RELN JUNB FZD4 C1S WISP2 DUSP2 CD2 SFRP4 LTBP2 FGL2 DUSP5 NELL2 IGLL1 KLRK1 PODXL2 DFFA KLF6 CXCL9 IL1RL1 TRIM45 SCNN1B CXorf57 ETAA1 ZNF185 FAM46A SFPQ PPP1R7 ARL4A RCAN1 NPY1R CPPED1 CLDN4 HMGB3 KIAA1324 PROM1 IL20RA	0.00013645	UP
REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	OCLN DSG2 TJP2 DSP CDH1 CASP3 DSG1 TJP1 CTNNB1 DSG3 PKP1	0.000143582	DOWN
FARMER_BREAST_CANCER_CLUSTER_5	THBS2 FILIP1L HTRA1 AEBP1 COL5A2 FBN1 SERPINF1 PCOLCE COL1A2 SPARC CTSK FAP CDH11 COL5A1 DACT1 COL3A1 ADAM12 SRPX2 NID2	0.000147535	UP
SERVITJA_ISLET_HNF1A_TARGETS_DN	SLC38A4 NR1H4 UGT2B15 FRK DDC UGT1A1 ADH1C VIL1 ACE2 PIGR HPGDS TMPRSS4 RNF186 SGK2 ENPEP TMPRSS2 FXYD3 CDHR2 FBP1 ANXA4 CBS MTMR11 CLIC5 GNG12 VLDLR NDUFS2 SLC37A4 MUC4 FH PFKFB2 RNASE4 PGK1 PFKL PDK1 DPP4 TPI1 ME3 AMBP TAT MSH5 TACR3 IGF1R SLC12A7 GC PRLR CDH8 TTR POU3F4 ELOVL2 CPB2 HNF4A PFKP FBP2 FFAR2 PKLR TRPM2 TM4SF4 GRTP1 ATP4A GLUL SLC26A1 G6PC2 GLP1R COX6A2 SEMA4A PCSK1 DCT PROC SERPINA10 SLC2A2 HGFAC CPN1 MLXIPL ETV5 ATP7A NPTX2 GPR137B GATM SULT1C2 HOPX PAMR1 CDO1 PPP1R1A	0.00014757	DOWN
LIEN_BREAST_CARCINOMA_METAPLASTIC	THBS2 TIMP3 IGF2 RUNX1T1 ADAMTS5 PKD2 MCAM PRRX1 KCNE4 SPARC MXRA8 COL16A1 LUM COL18A1 SFRP4 RARRES2 PPP1R12A ACAN EDIL3 TPM4 TBX2 TPM3 MSX1 MMP16 STAG2 IQCA1 PDGFRA PDGFA P4HB THBS1 HOXA7 POSTN	0.000149122	UP
SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_DN	ANK2 CLU TSC22D3 CCL21 CD69 CSRP2 TRIB2 ST8SIA1 RHOH TCEAL1 LY9 ITGA4 GLIPR1 CD180 GPR18 TRAF5 CD3D CD3E MEF2C PIK3IP1 CIRBP CD40LG ZMYND11 ATRX PDCD1 DNASE1L3 TXNIP POU6F1 CD101 WWP1 CSN2 TNFRSF25 TCF20 HSPA1L TXK STX16 PMCH ZNF141 HLA-A RAPSN INPP1 HES1	0.000150743	UP
HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS	FABP4 CNN1 TAGLN DMD CLU PDLIM3 OLFML3 CCL11 NDRG4 DKK3 SMTN CADM1 CLIP3 FBN1 CPE NUAK1 IGFBP7 TMEM45A COL4A2 COL6A1 UCP2 TSPAN2 NNAT ICAM1 SERPINE2 IER3 IL6 CXCL1 CDH2 ADA IFI6 TNFAIP3 MMP25 INHBA IGFBP3 BDNF APOE EDIL3 TGFB2 MX1 GABRA1 COL2A1 LRP1 SLCO1A2 VCAN NPC2 F2RL2 ABI3BP CTSB QSOX1 TACSTD2 NPPB MCM7 ITM2B RELB ITGA3 ASAH1 CUX1 HLA-C GADD45A IL32 ASS1 SDC4 ADM IGF2R FTH1 CXCL6 CREB3L1 CDKN1A FUCA1 FAT1 ABCG1 LAMC2 ACSF2 IFI27 TGFA	0.000152399	UP
NAKAMURA_ADIPOGENESIS_LATE_DN	CYR61 ACTG2 THBS2 TIMP3 TMEM47 MYH11 CXCL12 CALD1 DKK3 COL15A1 GDF15 GLIPR1 SERPINE2 SLC7A5 IL6 IER2 LRP3 SERPINE1 ZNF133 COL9A3 IGFBP3 TPM1 EDIL3 SRPK2 HCK EPOR PDE6D ABI3BP ITGA3 ITGAV SMAD3 RAI14 AIMP1 NT5E LOX HAPLN1 POSTN	0.000154092	UP
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN	RGS1 RTN1 TGFBR3 NID1 LTF CYP1B1 CALD1 KLF2 MAL GZMK CCR7 MYBL1 F13A1 HBB LBH MMP9 CSTA CRISPLD2 IL21R TUBB2A IL10RA ITGAM S100A8 GIMAP4 SPON2 ITGB2 MAN1C1 KCTD12 ARL4C LY9 PLXDC1 PVRIG RASGRP1 TYROBP LCK ITK CD27 C5AR1 NCF2 CTSH CD2 TESC IL7R TRAT1 CD86 GPR65 CPVL CCL4 CX3CR1 GPR18 SLC2A3 CEBPD FCN1 SAMHD1 FCGR3B MS4A6A PPBP CD3D MNDA CCR1 FGR CD163 DOK2 ZFP36L1 FGL2 CLEC10A CYBB NELL2 TNFAIP3 CD247 LRRN3 CLEC7A FPR1 MARCH2 ZAP70 PASK CD28 LEF1 FCER1G EPHA4 DOCK9 TGFBI GABARAPL1 KLRB1 CDK5R1 CD8A HBZ ETS1 RHD ANKRD55 NKG7 MMP8 S100A9 KLF1 KLRF1 SGK1 PRKCA RORA FYB KLRK1 HBD MEGF9 SNCA ARG1 IL2RB AQP3 CD1D CDKN2D CD14 ACSL6 IFI30 S100A12 CD8B CST7 TXNIP FCGR2A F5 BPGM MYL4 PF4V1 AHSP BCL11B ALAS2 SGSH PRF1 CHI3L1 HCK CD36 GNLY KRT1 IGSF6 ISG20 LYZ RHAG VCAN IL1RN GYPA CD5 STK17A GZMH SLC4A1 PIK3R5 S1PR5 STX11 CAMK4 QPCT PCSK5 PSAP SNTB2 XCL1 CCL5 SERPINB2 FAM46C FAM102A IL18RAP CTSB TUBB1 LILRA5 GZMB SLC14A1 CLEC4A CTSE ZER1 LGALS2 DENND2D RCAN3 CITED2 BCL2L11 PF4 PYHIN1 THBS1 TFDP1 BLVRB LDLRAP1 IGF2R NPL CTTN KLF4 IL13RA1 CEACAM8 LGALS3 TOB1 SECTM1 GZMA PLBD1 PNP SERPINA1 CA1 UPP1 SELENBP1 TMC5 CYP4F3 PTGDR XK OLFM4	0.000155358	UP
SASSON_RESPONSE_TO_FORSKOLIN_DN	TPM2 ACTG2 GEM AKAP12 CAP2 PDLIM3 ACTA2 AXL CDKN1C TUBA1A PRKD1 CDK14 FLNC RPRM DUSP14 RAB31 RGS5 ACTN1 ARL4C PLCL1 MAP4K4 RGS4 PIK3CD DAPK1 ADCY7 DAB2 TRIB1 CYFIP2 ILK TYRO3 ACTA1 TPM1 DYRK3 VCL RAB33B ACP5 MAPRE2 STIP1 CASP4 PI4K2A ARHGAP1 GBP1 NPC2 PPP3R1 RANGAP1 STK17A SMARCD1 TP53 ACTB PTPN1 PPP2R5C HSD17B1 MAP2K3 GNB1 TP53I11 PMAIP1 RASAL2 SRP72 ARL6IP5 STK25 LOC81691 STAT1 SH3BP4 TLK1 ITGA3 KIDINS220 GDI2 CAPZA1 ARHGAP35 ACTR2 ITGB5 ABLIM1 RAB5A DHRS3 THBS1 STK24 TK1 PTPRE PAWR RAB5C CARD10 ADCY9 TNFRSF11B CTNND1 PTPRF MAPK6 ATP9A KRT18	0.000155824	UP
WINTER_HYPOXIA_DN	CCL19 SYNE1 FBLN5 ARHGAP15 RHOH GYPC RGS5 IL16 HLA-DOB CD48 EVI2A LMO2 PTPRC FLI1 CD79A ICAM2 ARHGEF6 FAM65B DOCK2 ITM2A EVI2B INPP5D ZSCAN18 CELF2 ATM IKZF1 BCL2 CD28 ENPP2 PBXIP1 LRMP IRF8 TLR7 SYNRG ISCU ARL6IP5 FRZB ATP8A1 PARM1 CHPT1 TRAPPC10 SLC25A20	0.000156881	UP
NIELSEN_GIST_AND_SYNOVIAL_SARCOMA_DN	MFAP5 NNMT ZEB2 ANXA1 GPNMB IL10RA ITGB2 CSF1R TYROBP NCF4 CD4 FOLR2 SFRP4 CXCL1 CD163 TNFAIP6 C2 RNASE1 PLAU CTSD	0.000157212	UP
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN	FOS RTN1 GPM6B GREM2 ID4 ELAVL4 SYT11 INA CXCL13 SCRN1 C14orf132 STMN2 F13A1 SCG5 JAM2 VCAM1 PEA15 CORO1A FYN HAND2 MPPED2 CNR1 JAKMIP2 CSF1R LY86 TSPYL4 CSF2RB TYROBP MRC1 PKIA RGS4 MAPK10 CD53 TTYH1 SCARA3 CX3CR1 KCNA5 C1QB LST1 ST8SIA4 RUFY3 KIAA0408 RND2 MAP2 CADM4 BCL11A MAF RUNX2 TAL1 CDK5R1 GFRA1 SATB1 SCG3 OXCT1 ELAVL3 APC2 HDAC9 NAP1L2 MEGF9 CD1D ATAT1 NEUROG1 ABCD2 RBL1 MYT1 CACNG4 DCX LECT1 DLX5 GDAP1 BRSK2 INSIG1 CADPS SPATA6 NOL4 FOXG1 NHLH2 ASCL1 STMN3 PPP1R17 SLC4A5 ITGB8 FABP7 CNOT2 PRMT8 KAT2B POU3F4 EGFL6 RNH1 TBR1 PDGFRA NCAN ELAVL2 SHOX2 MDM4 PKNOX1 NEUROD4 ST18 NEUROD1 ARCN1 ALDH1A1 SLC17A6 ENY2 RAPGEF5 CTSC EDNRB SPAST CDK2AP2 NUDT21 HSD17B11 DACH1 ERMAP HPGD SGK3 PAK1 STX3 MYB	0.000157595	UP
WINZEN_DEGRADED_VIA_KHSRP	CYR61 PTGS2 CTGF GREM1 NR4A2 GEM CAV2 PPP1R3C FRY GPR183 TGFBR3 SCHIP1 HBEGF SDC2 TRPC1 SERPINI1 AMOTL2 SCG5 IRS1 DNAJB5 EREG ZFP36 LMO2 CXCL2 ADRB2 ELOVL4 PTGFR IL23A PKIA GDF15 TFAP2C SERPINE2 IL6 DUSP6 PTHLH DUSP5 SELE PDGFC CCL20 INHBA PAPPA BDNF IFIT1 CYP26B1 YPEL5 FST GPR1 CSF2 PLAUR SPRY2 CXCL3 PTGER4 YRDC CXCL10 DKK1 PMAIP1 ID2 TMC7 JAG1 SPRY4 PDGFA HAS2 CYP24A1 STK38L TNF SDC4 CXCL11 ZFAND6 IFIT2 B3GNT2 MUC13 EDN1 EDN2 ITGA6 F3 BMP2 ANKRA2 SMPDL3A F11R STYK1 CCDC68 ARL14 SLC4A4 SPINK1 TGFA	0.000158435	UP
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G	AKAP12 LHFP SMARCA1 WWTR1 MPDZ PMP22 DENND5A CAMSAP2 RDX LAMB2 AMOTL2 RHOH LAMC1 DIP2C CORO1A HCLS1 PTPRC LAPTM5 TSPAN4 GMFG LCP1 ULK2 MFNG NCKAP1L ENAH ANXA5 INPP5D PACSIN3 CD53 DRAM1 ARHGEF17 GJC1 PTPN7 CCND1 SWAP70 CD44 KIF21B TULP3 SYDE1 SH2D2A CDK6 FXR1 TNFRSF12A GABARAPL1 IL6ST GTF3A WWOX SGK1 OAZ2 PLK2 LOXL2 ABI2 LRCH4 IL2RG DEF6 CST7 PPP6R1 NINJ2 DST TFAP2A PSD4 NFIB MAX GAS2L1 PFN2 SSBP1 DAG1 NFE2L1 ARHGAP4 BMP1 VAMP3 PPA1 ITGAV SSBP3 FAM114A1 CKAP4 TPBG U2AF2 RNF11 DOCK1 REPIN1 VRK3 PRKX SEMA3C ELF1 ENOSF1 GNA11 IGSF3 BCAR3 GNG12 ASB13 MYB	0.000160019	UP
CHASSOT_SKIN_WOUND	FOS FOSB EGR1 EGR3 EGR2 KLF2 JUN JUNB REL ID3	0.000161025	UP
MATTHEWS_AP1_TARGETS	PTGS2 CAV1 HBEGF SPP1 FLNC LBH VIM SPRY1 CD44 PLAUR STMN1 MVD IL1RL1 MMP10 BCL3 CA3	0.000161635	UP
CHEBOTAEV_GR_TARGETS_DN	MYL9 PDZRN4 THBS2 IGFBP5 GPM6B DNAJC6 FLRT2 CH25H PDLIM3 PPP1R3C SMARCA1 LOXL1 NRXN3 CXCL12 SYNE1 PRKD1 MXRA7 EFEMP2 S100A4 LIMCH1 CRISPLD2 CPE COL1A2 ANKRD6 CPEB1 NPTX1 PALLD PKIA DMPK ZSCAN18 GFRA2 RTN2 VWA1 S100A3 ZFP36L1 STAG3 LRRN3 ALMS1 CNN2 CNTN1 PTPN14 IGFBP3 CLEC11A AR IRF4 SOX21 C2 DAB1 CA8 CACNB4 TGFB2 GNA14 SORCS3 PLA2G4A IL2RG SARDH RASA3 FKBP14 TUBA8 AMY1A FKBP10 GDNF DPY19L1 PTGER4 PFN2 USP18 SLC14A1 NRCAM TSC22D1 RSAD1 ELAVL2 MYEF2 SIPA1L3 ZC3H15 PLAT ATP6V1C2 FGGY TNFRSF11B ATP8A1 MOB3B RHOBTB3 STBD1 VAV3 LRP4 SLC38A4	0.000162559	UP
WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_DN	ZBTB16 GEM EDNRA MEIS1 CD93 PTPRCAP LY86 CD27 IL7R ERG NRGN CD34 FLT3 SATB1 ITGB7 CALCRL CD244 TSC22D1 TMSB10 NRIP1	0.000163285	UP
RICKMAN_HEAD_AND_NECK_CANCER_B	OGN SYT1 BCHE BEX1 MFAP5 NRN1 NRXN3 COL21A1 PNMAL1 OMD LRRC17 ARHGEF26 HLA-DQA1 COCH SFRP4 BBOX1 GPC3 COL3A1 EYA4 CALML5 COMP ZIC1 MAGEA4 CDKN2A USP9Y MAGEA10 PRSS21 COL11A1 HRASLS MAGEA11 CNTNAP2 PTH2R NLRP2 ELF5 CDKN2B EIF1AY UGT8	0.000164122	UP
PID_AP1_PATHWAY	CYR61 FOS FOSB EGR1 FABP4 ATF3 CCL2 DUSP1 MMP9 TGFB1 PENK JUN JUNB COL1A2 TIMP1 GATA2 NFATC1 NR3C1 IL6 CCND1 CBFB MYC GJA1 MAF ACTA1 ETS1 JUND NPPA PLAU FOSL1 TRIP6 NTS NFATC3 CSF2 DMP1 CDKN2A IL10 CRTC1 DMTF1 MAFG TP53 IL5 ESR1 HIF1A CTNNB1 ATF2 CDKN1B IL2 CREB1 IL4 IFNG MT2A BCL2L11 PTEN HLA-A EP300 COPS5 BAG1 CDK1 TH TCF7L2 FOSL2 ELF1 EDN1 SP1 MMP1 MYB AGT	0.000164968	UP
PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN	AHNAK2 UCHL1 TPM2 SRPX MLLT11 TAGLN CLU CAP2 ENO2 CCL2 NNMT RHOB CXCR4 ACTA2 AXL FAM107A EFEMP1 VEGFC PLTP DFNA5 ITGA5 FBXL2 ANXA6 EMP3 TGM2 PRNP JUN NUAK1 BASP1 RGS10 COL1A2 NPTX1 BTG2 ICAM2 ARL4C ARHGDIB ITM2A PKIA COL6A1 RGS4 LAMA5 BGN ARHGAP22 TRIM22 KLHL21 ICAM1 SRGN FAP SELP RAC2 IER3 IL6 NR2F2 LTBP2 APBB2 RRAS CXCL1 CDH2 CDC42EP3 CD44 LPXN CYFIP2 SELE LYL1 SERPINE1 TGFBI TFEC PFKM NISCH TPM1 PLOD1 LOXL2 RNASE1 PLAU LDHB ISG15 RCN1 SLC3A2 IGF2BP3 PLA2G4A PDLIM4 PGF AGRN FLT1 GBP2 MMP14 ECE1 SGSH SLC7A7 VCAN PROCR CHST1 TXNRD2 SRPX2 PFN2 IL4R DKK1 NRCAM TANK COL8A1 PCDH1 SLC6A8 ARL6IP5 STAT6 KRT7 TACSTD2 BMP6 MT3 EIF2B2 ITGAV CD59 TCN2 SMAD3 ITGB5 GADD45A SMURF2 MAPKAPK3 TRAM2 IL32 CTSC SLC38A6 MT1X MT1H EXT1 CAPG FHL2 MT1E MBOAT7 MT1F PRKACB CDKN1A ALDH2 ATP1B1 MECOM UAP1 TNFRSF21 LY75 SORD NMT2 EPS8 LAMC2 MVP IFI27 HMOX1 TP53I3 PLOD2 UPP1 MMP1 LAMP2 CCRL2 CLDN7 SLC1A1 ANXA3 ANPEP GLCE	0.000166686	UP
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN	LHFP MN1 KLF2 LPL DFNA5 CCR7 SELL GPX3 F13A1 PRNP BCL6 JAM2 CSTA MS4A4A GAS7 IL10RA MYLK FGFR1 S100A8 IL16 FZD2 CSF1R OAS2 BTG2 LY86 ANXA5 CD53 GLIPR1 GATA3 IL7R MAFB SLC16A7 SLC1A3 CEBPD CECR1 ADAP2 MS4A6A TCF7 HERC5 GPR137B MNDA CDH2 CCR2 ADA HLA-DMB FGL2 VAMP5 DACT1 TGFBI NINJ1 FLT3 NKG7 S100A9 SATB1 CRHBP IRF8 CRYGD GLTSCR2 CAPN3 MCL1 IFI30 CST7 VPREB1 LILRB4 TLR2 ELANE IRF7 ISG20 RPS11 RPL32 HMHB1 CLEC5A MPO RPS15 GADD45B RPS17 RPL18A TERT RPS24 RPL30 HAL DNTT RPS12 RPL39 RPLP1 EEF1A1 MYOF RPL23A SGCB CLEC4A RPL41 SH3BP4 ACTG1 HLA-C GAPDH HLA-B BCR PTPRE ADD3 SORL1 INSR BLNK KLF4 IL13RA1 FAAH FLNB ME1 EPB41L3 MVP ANK3 MYO5C ZNF124 PROM1	0.000167921	UP
DIRMEIER_LMP1_RESPONSE_EARLY	EGR1 EGR3 BCL2A1 EGR2 GPR183 CD69 PPP1R15A CCR7 CCL3 JUN JUNB ZFP36 BTG2 LCP1 DUSP2 CD83 ICAM1 CCL4 IER2 MYC PIK3CG CD40 DUSP5 TNFAIP3 NFKBIA JUND TRAF1 SERPINF2 LTA BIRC3 TNFSF9 SLAMF1 MCL1 NFKB2 KDM6B NFKBIE KLF6 UBE2M INSIG1 IRF7 MAN2B1 HSP90AB1 RPS16 GADD45B EEF2 PTK2B RPS9 ACTB RPS10 EIF1 EEF1A1 GNAT2 SEC24C NPPB ZC3H12A HERPUD1 SIAH2 TNF TRAF4 FTH1 MUC13 JUP HMGCS1	0.000169491	UP
GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP	PTGS2 NR4A2 FAM129A VNN1 GUCY1A3 TFPI TGFB1I1 RBPMS CXCL13 CCL19 PCDH9 HLX MAFF EVI2A EBI3 CXCL2 PTPRC KYNU CREM FNBP1 CYTIP GLIPR1 SVIL CXCL1 AREG INHBA FXR1 ALOX5 TM4SF1 IL18R1 CRHBP IL1B PPFIBP1 STAT4 GBP2 DST DDX17 CXCL3 CXCL10 SPTBN1 PMCH HIST2H2BE TRA2A TNFSF4 TSPAN31 ALDH1A1 TPBG H1F0 HIST1H2BK NFAT5 OPTN NRIP1 CXCL11 TCF7L2 FTH1 ANKRD12 SOD2 CXCL6 MLLT3 TNFSF10 HIST1H2AC EMP1 MPZL2	0.000176168	UP
RIGGI_EWING_SARCOMA_PROGENITOR_DN	EGR1 MAB21L2 SRPX PTGIS CLU SOBP DPYSL3 FHOD3 COL14A1 CSGALNACT1 PCOLCE2 ECM2 PPP1R3C TGFBR3 FBLN1 PDE4B SERPING1 PDZRN3 CXCL12 TMEM158 SCRG1 IGFBP6 MOXD1 BNC2 PDE1A HEG1 PLCB1 NRP1 GLT8D2 DCN PAMR1 LAMA4 PRRX1 C1R CHI3L2 GFPT2 SLIT3 COL6A2 SVEP1 C1S PTGFR BACE1 WISP2 RPS6KA2 HLA-DPA1 PPL BICC1 ETV1 SCARA3 ALDH1A3 SFRP4 STC1 PTN SHCBP1 CD44 LPXN DPYD DUSP4 PIEZO2 PTGS1 NRP2 MME STC2 RUNX2 HGF CLGN PHLDA1 NR1D2 STEAP1B CLDN11 FST ECM1 COL10A1 KCNK2 LRRFIP1 CHI3L1 WISP1 VCAN TRIOBP MMP16 ARNTL2 ADAM12 IL1R1 ANXA10 PDK4 WLS TANC2 RAB27B PDE7B BMP4 GDF5 KCNJ15 CUL4B CDCA3 KITLG PRG4 RRM2 ZNF395 PDGFRA PTGER2 BDKRB1 SLC12A8 GULP1 HAS2 DHRS3 IL13RA2 SLC2A5 BIRC5 PDK1 GPSM2 NEDD4L EGFR KIAA0101 CARD10 CXCL6 ITPR3 NUSAP1 DEPDC1 HEPH AVPI1 BUB1B SPON1 AIM1 ABHD2 NAMPT CA12 LXN TOP2A DLGAP5 HNMT CEP55 GALNT12 PRC1 CDCP1 F2RL1 GATA6 RARRES1 FAR2 ASPM PSD3 PBK ADORA2B	0.000176253	UP
ROY_WOUND_BLOOD_VESSEL_UP	CYR61 SULF1 CDH5 ANGPTL2 ANXA6 FBXL7 COL5A2 HEG1 NRP1 RAB31 S100A4 KCNJ8 CHN1 PEA15 COL4A1 THY1 MCTP1 PLXDC1 TIMP1 LUM PCDH17 STOM STC1 HLA-DRB4 CYFIP2 GNA12 DENND4B COL3A1 COL5A3 PLAU TES ANGPT2 HYAL1 GBP1 MSX1 VCAN SRSF11 XAF1 NID2 SLCO2A1 SGCB BMP1 GALNT2 SEL1L3 KDM5D ATG4A FKBP1B ZWINT POSTN MMP1	0.000177799	UP
SASSON_RESPONSE_TO_GONADOTROPHINS_DN	TPM2 ACTG2 GEM AKAP12 CAP2 PDLIM3 ACTA2 AXL CDKN1C TUBA1A PRKD1 CDK14 FLNC RPRM DUSP14 TUBB2A RGS5 ACTN1 ARL4C PLCL1 TLN1 MAP4K4 RGS4 PIK3CD DAPK1 ADCY7 DAB2 TRIB1 CYFIP2 ILK TYRO3 ACTA1 TPM1 DYRK3 VCL RAB33B ACP5 MAPRE2 CASP4 PI4K2A ARHGAP1 GBP1 NPC2 PPP3R1 RANGAP1 STK17A ARPC4 SMARCD1 TP53 PTPN1 PPP2R5C HSD17B1 MAP2K3 TP53I11 PMAIP1 RASAL2 SMARCA4 ARL6IP5 LOC81691 STAT1 SH3BP4 TLK1 CFLAR ITGA3 KIDINS220 CAPZA1 ITGB5 ABLIM1 DHRS3 THBS1 STK24 PTPRE EZR MAPK14 MBD2 PAWR RAB5C ATP2A2 CARD10 ADCY9 TNFRSF11B BECN1 CHUK CTNND1 MAPK6 ATP9A KRT18	0.000179372	UP
SENESE_HDAC1_TARGETS_DN	FOS NAP1L3 CNN1 TCEAL2 TUBB2B IGFBP5 TNS1 FXYD6 ID4 MYH10 PTRF RBPMS SMARCA1 ITGA7 MEIS1 FBLN1 NOTCH3 CSRP2 TUBA1A DKK3 TCEA2 MYBL1 PKD2 EFEMP2 OBSL1 LAMB2 FSTL1 BNC2 KLF7 IRS1 HSPB2 PNMA2 MYLK CPE COL1A1 SDC3 FGFR1 JAKMIP2 COL16A1 APLP1 ENAH ARID5B TRO LAMA5 HCFC1R1 FADS1 TCF4 TTYH1 KLHL22 SOX12 CADM3 DAB2 MRC2 RASSF4 LSP1 BCAM KCNA1 CDC42EP3 IFI6 CRMP1 COL5A1 SCN2B CDH13 GSN TGFBI MAF RUNX2 L1CAM COL3A1 GLI2 CIRBP PRKCA RASA4 ALOX5 UTRN BAIAP2 EDIL3 AHNAK ORAI2 PYGL CSDC2 TMEM120B LYPD1 DHRS2 RBM15 MTSS1L TGFB2 SOX2 CNPY4 EFNB3 PBX1 PTPRN LRRFIP1 SYNC DOK1 TK2 AASS GPC4 CYTL1 PARK7 SET EPB41L5 COL11A1 STMN3 MATN3 NOX4 VGF WRB ICAM3 GSTM2 FOLR1 TIA1 TSSC1 PIN1 BNIP3L CBX5 RNF187 IQCA1 BMP4 BTBD2 KRT7 TIAM2 NRBP1 SYT17 THRB MAGED1 ZNF395 GSTM1 PDE1C HSD17B10 NARF CYTH2 SLC38A10 EFCAB2 DNAJB2 FAM114A1 ARHGAP35 SSH3 COPZ1 GPATCH2 HDLBP DNAJC1 BAZ2B RAC1 ASS1 F2R IDH2 HDAC1 CDC42 EPHB2 EPS8L2 PGRMC2 ROCK2 S100A10 VAMP7 CCNG2 HR FDFT1 HAPLN1 FAM171A1 LSS EDN1 ARHGEF40 CHMP3 DPY19L4 CD46 ALDH5A1 RHOBTB3 NMT2 ABCC3 NUDT6 ALDH6A1 TMEM135 TRIM2 IFT74 CDC25C GOLM1 SDC1 TOX3 HMGCR IMPA2 GSTM4 RNFT1	0.000180974	UP
YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP	ATP1A2 PEG3 ADIPOQ GEM SDPR THBD NR4A1 MEIS1 NCAM1 CRIP2 LTF CDKN1C CFD LEPR PBX3 TNXB ELN LAMA2 HLA-DQB1 AQP1 KCNAB1 PROS1 CLDN5 PDPN RARRES2 B3GALNT1 DBP RBP1 BCL2 KLF10 ENPP2 IGFBP3 DDX50 CSF3R APOE KLF9 GSTT1 WNT4 FLT1 PIK3R1 USE1 KRT15 GAS6 CYP2E1 GSTA3 CDH16 REM1 ACTB AKAP8L CYP2F1 PRPF39 NBL1 TBX3 SENP6 CA3 CHERP ID1 NDRG2 IDH2 ADM ARL4A RNASE4 LCN2 ME1 XDH GDPD3 HMGCR	0.000182604	UP
NAKAMURA_ADIPOGENESIS_EARLY_DN	CYR61 ACTG2 THBS2 TIMP3 TMEM47 MYH11 CALD1 COL15A1 VCAM1 RGS4 GDF15 GLIPR1 SERPINE2 IL6 IER2 DAB2 LRP3 SERPINE1 ZNF133 COL9A3 IGFBP3 TPM1 EDIL3 SRPK2 HCK EPOR PDE6D ABI3BP ITGA3 ITGAV PRSS23 RAI14 STK38L NT5E LOX TNFRSF11B HAPLN1 POSTN	0.00018393	UP
AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP	PTGS2 GREM1 VNN1 NEFL DPYSL3 SFRP1 FEZ1 NNMT TNC ARMCX2 MAP1B SPOCK1 FN1 CALD1 PCDH7 KCNMA1 PLTP G0S2 GPX3 EMP3 SCG5 COL5A2 WIPF1 PRNP S100A8 GNG11 FLI1 ARHGAP25 OAS2 IFI16 ARL4C CLIC4 ARHGDIB PALLD SRGN SERPINE2 PDPN APOBEC3G CALU CDH11 AOX1 IFI6 LPXN COL5A1 DUSP4 TGFBR2 CDH13 SLC4A7 ROBO3 SH2D2A FOXA2 LTBP1 S100A9 TP63 CCND2 CDK17 CSF3 PLK2 MX1 FST DCBLD2 NUP188 NUPR1 PTPN11 CALB1 MCL1 CALML3 CUX2 MMP3 CPS1 TGFBR1 SRSF6 CDV3 IFITM1 NF2 STX16 STX10 DDX58 DDX3X DHX9 JAG1 GABPB1 ELAVL2 SSR3 CLDN1 RAB6A NUP160 WDR1 B4GALT1 RAB5A THBS1 IL13RA2 YKT6 SORL1 PTPRK CXCL11 XYLT1 COPA MAN1A1 G3BP2 VSNL1 RPS4Y1 IL13RA1 TWF1 PID1 CA12 PRSS3 IFI27 HMGCS1 HRH1 CYP51A1 FGFBP1 OAS1 TGFA ITGB6	0.000184264	UP
RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP	NR4A2 CH25H RGS2 GPR183 LTF G0S2 RGS13 MS4A1 CSTA LY96 P2RX5 ITGAM S100A8 ZNF331 PTPRC VNN2 LY86 CREM CYTIP GLIPR1 IQSEC1 SLC7A5 GPR65 GRK5 GPR18 CEBPB MNDA SWAP70 IDS DUSP4 DUSP5 USP36 AREG ZNF571 GABARAPL1 P2RY10 MAP3K8 AHNAK NOTCH2 KLF9 BIRC3 TXNIP GLUL ZNF165 ALAS2 ABCA1 DEFA4 DDX17 LYZ MAX DDX39B DIDO1 FOLR1 TCF25 C15orf39 KLHL2 IFNGR1 GTPBP1 ADAM28 ASAH1 ANKRD11 PELI1 EZR SEL1L3 CD55 FOSL2 ITPR3 IL13RA1 MFN1 CHPT1 TRAPPC10 AIM1 CA1 IL1R2	0.000189853	UP
CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN	FOS FOSB CTGF TPM2 NR4A2 THBS2 PTGER3 SULF1 TSC22D3 ACTA2 NOTCH3 DCLK1 DUSP1 SMARCD3 HSPB6 PPP1R15A LAMA4 BCL6 COL6A3 JUN COL4A1 C10orf10 BASP1 COL1A2 IGFBP7 SPARC CD81 COL16A1 ITM2A FSCN1 IER3 IL6 IER2 TOX IGFBP4 GJA1 PTP4A3 TGFBI IGFBP3 TPM1 PIM2 NFKBIA SBNO2 NUPR1 APOBEC3C MCM3 CCNF NASP RECQL4 STMN1 CADPS VCAN SLC25A4 CDC45 LAMB1 TROAP HIST1H2BJ TSC22D1 MCM7 LUZP2 TRAIP HTT H2AFX ZMIZ1 PTTG1 AURKB UBE2C HIST2H2AA3 ID1 SNRPA1 TK1 ARHGAP11A SFTPB CDK1 MCM2 HIST1H4B HES1 INPP5J KIF2C RPS4Y1 CENPE CDKN3 CKS1B CLC EZH2 CDC6 TPX2 FOXM1 MKI67 CCNB2 RAD51AP1 CDC20 SLC20A1 POSTN DLGAP5 CCNB1 AURKA CCNA2 CENPA	0.000191476	UP
POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN	MGP UCHL1 IGFBP5 ELAVL4 APOD CXCR4 NID1 PBX3 SCG5 LAMC1 COL1A1 COL1A2 CNR1 C1S TCF4 ALDH1A3 LTBP2 INSM1 NFATC4 LMO4 TMSB15A BCL2 COL3A1 GLI1 NTRK3 IRF8 NDP NHLH1 CCND3 NFATC3 MYCN RPL35A NMU RPS11 VCAN RPL9 RPL24 RPL10A RPS17 RPL21 RPS23 RPS10 RPL39 RPL7 RPL34 RPL36A PTCH1 RPS29 RPS18 TPT1 EEF1B2 QSOX1 RND3 FIG4 TCF12 CYFIP1 TFDP2 GCNT2 SHROOM2	0.000215152	UP
KEGG_LEISHMANIA_INFECTION	FOS PTGS2 C3 TGFB1 JUN ITGAM HLA-DOB ITGB2 HLA-DQB1 HLA-DQA1 TGFB3 NCF2 ITGA4 HLA-DRA HLA-DPA1 NCF4 HLA-DMA HLA-DRB5 PRKCB HLA-DRB1 FCGR3B HLA-DRB4 MAPK12 HLA-DMB HLA-DPB1 NCF1 PTPN6 CR1 NFKBIA IL1B TGFB2 RELA FCGR2A JAK1 TLR2 IL10 IL12A TLR4 MAPK11 FCGR2C HLA-DOA TAB1 ELK1 IL12B ITGB1 MARCKSL1 IFNGR1 NOS2 JAK2 STAT1 IL1A NFKBIB IL4 IFNG MAP3K7 FCGR1A IRAK1 TAB2 NFKB1 TRAF6 CYBA TNF MAPK3 MAPK14 IFNGR2 IRAK4 MYD88 MAPK1 MAPK13	0.000240029	UP
TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_DN	ASPN RGS1 SRPX THBS2 CAP2 CXCR4 THBS4 FN1 SPP1 AEBP1 COL5A2 WIPF1 RFTN1 PRRX1 FBN1 COL6A3 COL4A1 COL1A1 ASAP1 COL1A2 COL4A2 IFI44 BGN C5AR1 SFRP4 LCP2 COL5A1 MMP2 COL3A1 TACC3 LRRC15 MXRA5 COMP COL10A1 WISP1 LYZ COL11A1 VCAN BTN3A3 RABEP2 NACA MMP11 ADAM12 LAMB1 COL8A1 UGCG RAB26 INVS TYMS LOX GMFB CDK8 EPPK1 PDE8A STK39 POSTN SAR1B GNA13 ECT2	0.000244838	UP
COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP	ATP1A2 APOD SPOCK1 HTRA1 SERPINA3 SCRG1 ANGPTL2 DKK3 RASSF2 GPRC5B CPE PLEKHB1 PDZD2 SERPINE2 TYRO3 ALDOC SOX10 GLUL OLIG2 EEF1A1 TF ITGA3 GFAP PLA2G2A RTN3 HLA-A FTH1 SOD2 TNFRSF21 SCD TSPAN7	0.000246861	UP
FRIDMAN_IMMORTALIZATION_DN	CTGF IGFBP5 TGFB1I1 FILIP1L TSPYL5 HTRA1 CYP1B1 IGFBP6 IGFBP7 SPARC IFI16 HSPA2 ALDH1A3 NDN IGFBP4 SERPINE1 IRF5 C9orf3 IGFBP3 AHR CDKN2A IRF7 TP53 MAP2K3 RB1 CREG1 HPS5 MAP1LC3B CXCL14 OPTN CLTB CDKN1A HTATIP2	0.00025003	UP
PHONG_TNF_TARGETS_UP	FOS EGR1 GEM ATF3 EGR2 DUSP1 DUSP10 BHLHE40 EREG JUN JUNB ZFP36 CXCL2 TNFAIP2 CD83 ICAM1 IER3 IL6 IER2 CEBPD EPHA2 CXCL1 CD44 DUSP5 TNFAIP3 ADAMTS9 CCL20 INHBA KLF10 FJX1 LDLR REL BTG3 NFKBIA PLK2 PLAU ZFP36L2 BIRC3 MCL1 CCNL1 NFKB2 IL11 CSF2 BTG1 KLF6 DUSP8 CXCL3 NKX3-1 LIF ETS2 TNFRSF10B PTX3 IRF1 SDC4 BIRC2 IFNGR2 IER5 KDM6A BMP2 LAMC2 NUAK2	0.000251998	UP
ELVIDGE_HYPOXIA_UP	CYR61 FOS EGR1 AHNAK2 SRPX AKAP12 ATF3 IGFBP5 ENO2 PTRF CSGALNACT1 CXCR4 CAV1 LOXL1 SPOCK1 CYP1B1 ITPR1 DUSP1 VEGFC CSRP2 SAMD4A OBSL1 KLF7 BHLHE40 CADM1 BNIP3 S100A4 LIMCH1 DPYSL2 SFXN3 TMEFF1 JUN MAFF PFKFB3 OLFML2A FYN PAM TMEM45A SPRY1 WISP2 TNFAIP8 HCFC1R1 GDF15 DDIT4 PDGFRL PDGFB DTNA NR3C1 HLA-DRB1 STC1 BBX ANGPTL4 GJA1 SERPINE1 STC2 TGFBI IGFBP3 RBPJ NOL3 PIM1 SH3GL3 ALDOC PTPRO PRKCA PXDN RASA4 PHLDA1 INHA DAAM1 LOXL2 ZNF292 YEATS2 RLF ARTN ORAI3 KLHL24 UPK1A SPAG4 TXNIP RRAGD KLF6 ECE1 ATXN1 DPYSL4 BCOR PLAUR KRT15 SLCO4A1 DST ISG20 B3GNT4 SRCAP PPFIA4 WSB1 GADD45B GYS1 PFKP ANKZF1 HEY1 KDM4B CA9 SCNN1B TIPARP BNIP3L S100A2 QSOX1 KDM3A KRT7 ZMYND8 TRA2A ZNF395 YPEL1 P4HA1 CD59 ATG14 CITED2 SRD5A3 INSIG2 VEGFA EFNA3 AK4 S100A6 PDK1 GPR87 GLRX ADM SCARB1 RBCK1 SORL1 ANG PGK1 SAT1 RNASE4 CYB5A EGFR SLC2A1 CCNG2 LOX ILVBL FLNB MXI1 PGAP1 FAM162A ELF3 DDR1 FAM13A P4HA2 GBE1 SOX9 VLDLR MET PLIN2 NDRG1 ASPH STBD1 PLAC8 OPN3 NFIL3 PGM1 ZNF654 HK2 EGLN3 EGLN1 DSC2 ADORA2B	0.000253998	UP
MCDOWELL_ACUTE_LUNG_INJURY_UP	CYR61 FOS AKAP12 TNC NR4A1 LTF DUSP1 MAL SPP1 ELN S100A8 ZFP36 BTG2 OSMR SLFN12 STEAP4 MYC ANGPTL4 PLA2G7 TGFBI PTGES COL3A1 SPHK1 TPM1 LTBP1 NFKBIA MCL1 FCGR2A KLF6 IL4R KLHL2 EIF1AX SERPIND1 SFN PTX3 LOX TXNRD1 CDKN1A RBM3 LCN2 LITAF CSTB NDUFS1	0.00025603	UP
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN	SYNM MAB21L2 SRPX ACTG2 MEIS2 AMIGO2 HSPB7 CCL2 FILIP1L PDZRN3 VGLL3 TMEM158 ADAMTS5 C16orf45 GPNMB SPEG ADAM19 SCG5 IRS1 ANGPT1 NRP1 GLT8D2 BNIP3 RFTN1 PRRX1 EREG CHN1 GFPT2 MAFF RBMS3 COL1A2 SPARC SH3BP5 EHBP1 LRRC17 ACTN1 OSMR LMCD1 LUM RPS6KA2 PKIA BAALC NR3C1 IL6 ALDH1A3 SLC1A3 SLC2A3 NR2F2 VSTM4 DAB2 TSPAN5 STC1 SVIL CDC42EP3 CD44 RECK COL5A1 AK5 SLC4A7 MAP2 SERPINE1 ATP7A MATN2 CEP135 MME CLCF1 STC2 AFF3 ENPP2 IGFBP3 FAM198B ZNF365 COL3A1 NUDT7 CHST7 DOK5 EYA4 HIP1 LTBP1 PRDM1 PHLDA1 LOXL2 PLAU EIF5A2 NRG1 FST DCBLD2 PDLIM4 GPR1 ELL2 FOXD1 SYNC MMP14 PLXNA1 TBX2 PRR16 SEMA7A CHI3L1 GRIA1 ARHGAP1 ZNF281 ADAMTS12 COL11A1 VCAN FAM69A ITGB8 ADAM12 SLC8A1 SERTAD2 IL1R1 ZNF239 NID2 CA9 SEC63 LIF DKK1 COL8A1 QSOX1 TANC2 TLE1 CREG1 LTBR PTGER2 PDE1C SEC24D HAS2 PPP1R7 HMGA1 AK4 SMAD7 ASS1 RAB27A ADM NRIP1 OSBPL1A SERPINB7 NEDD4L MICAL2 EGFR SEMA3C DMXL2 PPP2R3A FAM63A HR MARCKS TNFRSF11B MOSPD1 AKR1C1 PEX2 F3 PID1 ARHGEF5 ABHD2 SEMA5A CA12 GCNT1 PRSS12 INPP4B RPS6KA6 DENND1B PLOD2 TNIK ELOVL6 SOAT1 HMGA2 GATA6	0.000256361	UP
GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP	OGN SYNM GAS1 ACTG2 CNN1 MFAP5 FHOD3 FEZ1 OLFML3 FBLN1 NDRG4 SCN3A NR4A3 LDB3 DKK3 RRAD C1R ARHGEF3 NUAK1 SLC16A4 COL6A2 NPR3 C1orf54 BTG2 SPRY1 CX3CL1 LY6E OSMR IFI44 COL6A1 TGFB3 RGS4 TEK ST3GAL5 TTLL7 CTSH PDGFB DRAM1 SCARA3 DYSF LIFR C1QTNF1 SLC1A3 CEBPD LTBP2 PLCG2 DAB2 CLIP4 MAPK12 ZFP36L1 TOX ADAMTS2 MATN2 SNTA1 MME FMOD PNRC1 PTP4A3 OTOR EPHA4 PIK3IP1 COL3A1 GM2A MAP3K8 PCDHB11 S100A13 TLR1 AHR LDHB PREX2 MFAP2 ISG15 NSD1 FST ARFGAP3 PCID2 GSTT1 ECM1 ARSB CACNA1G JARID2 ZFAND5 DNASE2 GJB3 GPC4 GAS6 FGF5 CNP ATP8B4 SLC7A2 ADAMTSL4 CSAD RCBTB2 GSTM2 FAM189B HNRNPA3 IL4R PIBF1 EMILIN2 PRRC2C SYNPO ECHDC2 BMP4 RBM26 TLE2 ZNF185 BTN1A1 PLXDC2 SDF4 ARHGAP28 ABLIM1 TMEM176A TDRD3 PLAT ENY2 PSTPIP2 TMEM176B NT5E AUTS2 EGFR CAST CARD10 LOX IFIH1 TNFRSF11B LMO7 FCGRT SKAP2 LGALS3BP EPN3 LGALS9 TMEM30A PLEKHA6 PLCE1 SERPINB1 DECR1 PIR CDA PCTP F2RL1 IL18 CLMN	0.000258095	UP
AMIT_EGF_RESPONSE_60_MCF10A	CYR61 EGR1 PTGS2 CTGF DLC1 CALD1 KLF7 BHLHE40 JUN JUNB CXCL2 MAP3K14 GLIPR1 MAGED2 IER3 IL6 IER2 DAPP1 TRIB1 TNFAIP3 INHBA TPM1 TP63 PLK2 C11orf68 RANBP3 MGMT PTGER4 RND3 ZC3H12A GADD45A ID1 TOMM22 PDLIM5 HES1 SLC35D2 ITGB6	0.000260194	UP
GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN	VNN1 GUCY1A3 HLF TFPI TGFB1I1 RBPMS SCHIP1 FHL1 PCDH9 SELL LIMCH1 HLX HLA-DQB1 CD52 HLA-DQA1 GLIPR1 HLA-DPA1 HLA-DMA BAALC DUSP6 CXCL1 HLA-DRB4 HLA-DMB HLA-DPB1 IDS AIF1 AREG ALOX5 TM4SF1 CRHBP PPFIBP1 GBP2 SPTBN1 PMCH HIST2H2BE SPINK2 APP H1F0 SORL1 CXCL6 MLLT3 TSPAN6 EMP1 MPZL2 PROM1	0.000266698	UP
WANG_LSD1_TARGETS_DN	FOS EGR1 SYT1 EGR2 STXBP1 PCSK2 CHGB CPE JUNB SNAP25 TRO PCSK1N CHST8 RAB3A SYN2 POMC LHB ESM1 CGA POLR3D BTG1 ECE1 GH1 RIMS3 CHGA DLL3 ATF5 CPLX2 TSHB RIMS2 PRL CISH GADD45A CCNB2 PCLO	0.000268734	UP
PLASARI_TGFB1_TARGETS_1HR_UP	CYR61 PTGS2 EGR3 ID4 NR4A1 EGR2 HBEGF FBLN2 BHLHE40 JUNB MAP3K14 IER3 IL6 SNAI1 SERPINE1 KLF10 CDK5R1 FGF18 RASL11B GADD45B LIF ID2 ZMIZ1 GADD45G SMAD7 ID1 SPSB1 HES1 IER5 SLC20A1 NUAK2	0.000270801	UP
GU_PDEF_TARGETS_UP	CTGF TNC ZEB1 SDC2 FN1 DKK3 ITGA5 LAMB2 SERPINI1 COL5A2 WIPF1 TGFB1 LAMC1 COL6A3 COL4A1 COL1A1 COL6A2 FZD4 VIM COL16A1 VEGFB COL4A2 DOCK10 DOCK4 COL6A1 MAP4K4 PIK3CD TCF4 MAPKBP1 RAC2 CDH11 CDH2 COL5A1 SERPINE1 LEF1 TGFBI PLCG1 PRKCA SNAI2 COL13A1 MAPKAPK2 FZD8 TCF3 FZD1 RAC3 CDH18 SERPINB3 HIF1A PTK2 COL4A5 SERPIND1 ITGA3 SMAD3 VEGFA COL4A6 SMAD2 DOCK1 HDAC1 MAPK9 SERPINB7 PIK3C3 SMAD1 SMAD4 WNT5A ITGA6 BMP2 LAMC2 SERPINA1 PLCE1 PLCB4 SDC1	0.000272714	UP
BURTON_ADIPOGENESIS_PEAK_AT_0HR	OGN GAS1 MGP MYL9 CRYAB THBS2 TIMP3 ACTA2 RUNX1T1 VEGFC KLF2 LPL SPP1 SERPINB9 FZD2 ASAP1 IGF1 CTSK TLN1 TGFB3 PDGFRB MAP4 DAB2 NOV TPM1 UBE2L6 CYB5R1 RASL11B APBB1IP RALGDS TRIB3 ISG15 DDIT3 CSF1 MXD4 AES FLOT1 COL11A1 RAB11FIP5 NAA10 COL8A1 PDGFRA SERF2 GADD45A HLA-G PLAT FAH GAS2 PSMB10 CCNG2 MARCKS F3 SORD PLIN2 IDH1 PCK2 PCCB CALML4 ADH1C	0.000294562	UP
WENG_POR_TARGETS_GLOBAL_UP	CYP2B6 CYP2C18 AQP8 GSTA2 ETHE1 CYP51A1 HMGCS1 SCD CYB5B MSMO1 IDI1 FDPS DHCR7 SQLE GSTM2 GSTA3 CYP7A1 GSTM3 GCK	0.000302908	DOWN
WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER	RGS1 PEG3 CNN1 ADIPOQ GUCY1A3 PTGER3 NR4A1 ZCCHC24 MYH11 DPT TGFBR3 LOXL1 NR4A3 SCRG1 MITF HBB COL5A2 COL6A3 CPE CLIC2 LMO2 PECAM1 ITGB2 PTPRC LAMA2 IGF1 HLA-DQB1 GATM ETV1 CX3CR1 PLEK FGL2 LRIG1 PXDN RARRES3 VCAN PTX3 KLF4 UBL3 PRKCD FCGRT CES2 TSPAN8 GCHFR COBL USH1C SLC4A4 ERBB3 SPINK1 ANPEP PROM1 FMO5	0.000308185	UP
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP	VIP OGN MGP ASPN FABP4 TAC1 AOC3 SDPR MMRN1 SGCE CXCL13 CAV1 HTRA1 DIXDC1 SEMA3G COLEC12 CSTA C1R VCAM1 SPARCL1 LY96 SFXN3 NPR3 LRRC17 ULK2 ATRNL1 TYROBP LHX6 PRKCB FAP GIMAP5 NRGN SLC1A3 MS4A6A B3GALNT1 PRKD3 PTGS1 HDC ADAMTS2 SP110 PIK3R3 FGF18 NMB RNF130 CPA3 NAB1 TIPIN KLF9 XPOT RPRD2 AGBL3 CASP4 ZNF639 SLC25A37 AMY1A GPR182 NCL IARS PTPRB RHEB PFAS QPCT MYO1C DVL1 PIAS2 SLC25A12 SSR1 RIC8A MPP6 ZNF787 CALCA SYNCRIP ZNF318 TLE1 GIN1 SDCBP EIF2AK2 LRPAP1 TREM2 PAIP1 EIF2S2 UBQLN2 SESN1 B2M SPINK2 ORC6 ZNF185 ATP6AP2 SERINC3 MBD1 TAF9 ACYP2 PRDX1 SMURF2 SMG7 PTEN RPS6KB1 RNF11 USP33 ALDH9A1 KTN1 UBE2V2 USP16 NTAN1 IFRD1 SLC16A3 EBAG9 CTSO HPRT1 IGF2R MED21 GCLC EGFR CAST SCYL3 C1GALT1C1 DEPDC1 PDCD10 AGL SLC35A5 CRIPT PSMC6 P4HA2 MARCH5 GBE1 TMEM30A RNF7 SPRYD7 ACAT1 CFTR SMPDL3A PHYH GFPT1	0.000313763	UP
JI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN	THBS2 CXCL13 LOXL1 NCAM1 FN1 VEGFC DCN FGFR1 TIMP1 LUM PDGFRB ITGBL1 MMP2 C2 WNT2 NEDD9	0.000319259	UP
KEGG_OXIDATIVE_PHOSPHORYLATION	NDUFS1 PPA2 SDHB SDHC COX5A SDHD NDUFS2 NDUFB7 ATP6V0A2 ATP5G3 CYC1 ATP6V1D NDUFA10 ATP6V0D1 NDUFA9 NDUFS4 SDHA NDUFB3 ATP5D NDUFS3 ATP5B NDUFS7 UQCRFS1 UQCRC1 UQCRC2 ATP5G1 COX5B NDUFV1 COX10 NDUFA8 NDUFB6 NDUFC2 COX15 NDUFA6 ATP5F1 UQCRQ NDUFC1 COX6A1 NDUFB5 ATP6V1C1 COX7B ATP5A1 ATP6V1A ATP5C1 NDUFB2 ATP5J2 COX7A2 NDUFA5 NDUFA7 ATP6V1C2 UQCR10 NDUFAB1 COX8A COX6B1 NDUFS6 NDUFA2 UQCR11 COX6C ATP5O ATP6V1B2 ATP5J ATP6AP1 ATP5H NDUFA1 COX11 NDUFV2 UQCRH COX4I1 NDUFB4 COX7C ATP5L ATP6V1H NDUFB1 ATP6V0B NDUFS5 ATP5I NDUFB8 COX17 NDUFS8 PPA1 NDUFA3 ATP6V0C ATP6V0A1 COX7A2L ATP6V1E1 ATP5G2 ATP6V0E1 UQCRB ATP5E NDUFA4 ATP6V1G1 ATP4B LHPP ATP6V0A4 ATP12A ATP4A COX6A2 ATP6V1F ATP6V1B1 TCIRG1 NDUFA4L2 ATP6V1G2 ATP6V0E2 COX7A1	0.000340547	DOWN
FRIDMAN_SENESCENCE_UP	CTGF CRYAB IGFBP5 TGFB1I1 FILIP1L TSPYL5 RHOB CDKN1C FN1 CYP1B1 IGFBP6 RAB31 PEA15 COL1A2 IGFBP7 SPARC VIM TNFAIP2 IFI16 HSPA2 ALDH1A3 RRAS CCND1 RGL2 NDN CD44 TNFAIP3 IGFBP4 SERPINE1 IRF5 GSN C9orf3 IGFBP3 ISG15 NRG1 TES CDKN2D RAB13 ESM1 S100A11 CDKN2A IRF7 TFAP2A TP53 RBL2 SERPINB2 MAP2K3 MDM2 RAB5B ING1 CREG1 STAT1 NME2 EIF2S2 HBS1L HPS5 MAP1LC3B IFNG CXCL14 IGFBP1 GUK1 CITED2 SMURF2 RAC1 THBS1 SOD1 OPTN CLTB CDKN2B CDKN1A SMPD1 RABGGTA IGSF3 F3 IGFBP2 MMP1 HTATIP2	0.000347867	UP
KEGG_VIRAL_MYOCARDITIS	DMD MYH10 MYH11 CAV1 HLA-DOB SGCD FYN SGCA ITGB2 LAMA2 HLA-DQB1 HLA-DQA1 HLA-DRA HLA-DPA1 ITGAL HLA-DMA ICAM1 HLA-DRB5 CD86 RAC2 HLA-DRB1 CCND1 HLA-DRB4 HLA-DMB HLA-DPB1 CD40 CD28 SGCG CD40LG MYH3 PRF1 RAC3 HLA-DOA MYH7 MYH8 ACTB MYH13 CD80 MYH6 MYH4 DAG1 ABL2 ABL1 SGCB MYH9 EIF4G1 MYH2 ACTG1 EIF4G2 MYH15 EIF4G3 MYH1 CASP9 HLA-E HLA-C HLA-G BID HLA-B HLA-A HLA-F RAC1 CASP8 CD55 MYH7B CYCS MYH14 CASP3 CXADR	0.000355598	UP
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN	PTGS2 BCL2A1 EGR2 RHOB DUSP1 PCDH7 SPP1 ITGA5 BHLHE40 CCL3 PDLIM7 JUNB CXCL2 TNFAIP2 CSF2RB DUSP2 PDGFB CD83 ICAM1 RAC2 IER3 NAB2 CCL4 SLFN12 CEBPB SOCS3 CD44 TNFAIP3 PIM1 NFKBIA PHLDA1 CSF3 EHD1 TRAF1 FOSL1 ODC1 IL1B CD14 TNFSF9 NFKB2 TXNIP PLAUR PHLDB1 IL1RN GADD45B SLC11A1 IKBKE CCL5 IL18RAP MARCKSL1 UBC BCL3 TAPBP TSC22D1 ACTG1 CDC42EP4 SQSTM1 PDGFA ETS2 HERPUD1 GADD45A GAPDH MT2A NFKB1 VEGFA BCL2L11 UBB VMP1 PTPRE TNF GLRX BCL10 TNIP1 RREB1 SCD ADORA2B	0.000358138	UP
MODY_HIPPOCAMPUS_NEONATAL	ACTG2 TUBB2B TNC NCAM1 FN1 TUBA1A LPL NRP1 COL4A1 CHL1 CDH2 ST8SIA2 TUBB L1CAM TUBB3 MMP14 TUBA3C TBCA ACTB FABP7 CCT4 CCT7 SQLE TUBA4A FASN ACTG1 CCT8 MYEF2 UBA1 USP22 TARS CCT5 FDPS UBE2E3 FABP5	0.000360714	UP
KEGG_STEROID_HORMONE_BIOSYNTHESIS	UGT2B17 UGT1A8 UGT2A3 UGT1A3 UGT2B15 UGT1A6 HSD3B2 UGT1A1 UGT1A9 AKR1C3 HSD17B2 SRD5A1 HSD11B2 UGT2B28 AKR1C2 AKR1C1 HSD17B8 CYP3A5 CYP3A43 HSD17B12 HSD17B3 AKR1C4 CYP3A4 SULT1E1 CYP3A7 UGT2B4 SRD5A3 AKR1D1 CYP17A1 CYP19A1 HSD17B1 CYP11A1 HSD3B1 STS COMT UGT2A1 CYP7A1 HSD17B7 SULT2B1 CYP1A1 CYP7B1 SRD5A2 CYP11B2 CYP11B1 CYP21A2 HSD11B1 CYP1B1 HSD17B6	0.000376305	DOWN
ZHAN_MULTIPLE_MYELOMA_PR_UP	ASPM E2F8 PRC1 TTK NEK2 AURKA CCNB1 DLGAP5 TOP2A ZWILCH CCNB2 FOXM1 TPX2 SPC25 EZH2 BUB1B NUSAP1 RACGAP1 SLC19A1 KIAA0101 SKA1 CDK1 TYMS KIF14 BIRC5 UBE2C KPNA2 MAGEA1 FANCI RRM2 MAGEA6 MCM10 DSCC1 MAGEA3 TRIP13 PRR11 RFC4 TSR1	0.000382342	DOWN
CAIRO_LIVER_DEVELOPMENT_UP	GAS1 FGF13 IGFBP5 TMEM47 ARMCX1 PCOLCE2 RHOB ARMCX2 SMARCA1 PDZRN3 LDB2 SNN CSRP2 SMARCD3 CDK14 AKT3 RPRM PTBP2 CAPN6 TRPS1 COL5A2 SEPT6 WASF1 SEMA3A COLEC12 TMEFF1 JUN PLS3 EMCN FGFR1 FZD2 BASP1 EVL HAND2 PDZD2 EHBP1 TSPYL4 CD248 NES TRO ZNF423 NNAT SRM KCTD15 SERPINE2 PDPN MAP4K1 KLHL22 GJC1 CRABP2 CBFB PTN NDN RECK FLRT3 GPC1 DUSP4 PDGFC POLR1E SERPINH1 GJA1 SLC39A6 NR2F1 RAB11FIP3 GDF10 HBZ RARB SATB1 SH3GL3 PXDN PRPH2 BNC1 AFAP1 PRRX2 PLK2 ARPP19 MFAP2 TGFB2 SEMA3D MEX3D WT1 GRWD1 RCN1 SMARCA2 MYCN HBE1 FAM174B CYSLTR1 TBCB MDK LRFN4 HOXC6 FKBP10 WISP1 PTPRS ITGA8 PNO1 ASB4 RNF219 CST6 SLC25A4 BYSL CDH16 CTBP2 HMGN3 RRP8 SPATS2 POGK PFN2 TTC3 MARCKSL1 RWDD1 SRSF7 PGK2 WLS MAK16 LPAR4 MGAT5 HDAC2 PAFAH1B3 PDGFRA UTP3 SMYD2 SLC22A3 HMGN1 TULP4 PFDN4 TBX3 FKBP3 PTX3 RBM34 RCN2 IGF2BP2 IFRD1 TMEM184C EDNRB ID3 TGIF1 GOLT1B TMEM50B PPIC RNF138 EFNB2 HEPH DLG3 LRP12 SYNE2 SLC12A2 LXN NPAS2 SOCS6 NEO1 PLOD2 TSPAN6 MEST KIFAP3 HMGA2 CPM PITX2	0.000383144	UP
REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM	ACADSB ACAD8 BCKDHB AUH HIBCH ACAT1 MCCC2 ALDH6A1 IVD DLD MCCC1 BCAT2 HSD17B10 BCKDHA BCAT1 DBT	0.000388722	DOWN
KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM	UGT2B17 UGT1A8 UGT2A3 UGT1A3 UGT2B15 UGT1A6 UGT1A1 UGT1A9 ALAS1 HCCS HMOX1 UGT2B28 FECH COX10 COX15 CPOX GUSB FTH1 ALAD BLVRB UGT2B4 HMOX2 HMBS EPRS UROD UGT2A1 UROS PPOX ALAS2 CP BLVRA	0.000391233	DOWN
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE	HIST1H2BC HIST1H4H HIST1H2AE HIST1H2BH CENPA HIST1H2AC OIP5 HIST1H2BD HIST1H2BG MIS18A HIST1H2BE HIST1H2BI HIST1H2BF CENPN HIST1H2AJ RSF1 HIST1H2BM HIST1H4K HIST1H4B HIST1H2BK HIST1H4J HIST1H4D HIST1H2AD HIST2H2AA3 HIST1H4F HJURP H2AFX HIST1H4C ITGB3BP HIST1H2BO HIST1H4L HIST2H4A HIST1H4A HIST2H2BE MIS18BP1 RBBP4 HIST1H2BB HIST1H2BJ H2AFZ SMARCA5 HIST1H4E CENPQ HIST1H4I CENPO RBBP7 HIST1H2AB NPM1 RUVBL1 HIST1H2BN HIST1H2BL CENPI	0.000393521	DOWN
REACTOME_PEROXISOMAL_LIPID_METABOLISM	ACOX1 AMACR FAR2 SLC27A2 AGPS PHYH IDH1 ACOT8 ACAA1 HSD17B4 CROT SCP2 ACOX3 SLC25A17 GNPAT CRAT ACOX2 ABCD1	0.000400548	DOWN
BIDUS_METASTASIS_UP	PBK ECT2 SRD5A1 CEBPG MAD2L1 NRAS AGAP1 RFC5 CENPA TMEM33 KIF4A TTF2 GMNN KIF11 CCNA2 DSP AURKA HMGB3 RCOR1 CCNB1 DLGAP5 PLOD2 KIF1B CHEK1 MAPK1 FBXO3 CCNB2 VDAC1 MAPKAPK5 CCDC47 DHFR MED14 TPX2 DNAAF2 ATP6V0A2 MRPL42 RMND5A SEC23A CDC6 TFRC MPHOSPH9 CENPF C5orf22 DEPDC1 PLK4 RRN3 RNF138 LMNB1 EIF4E NUSAP1 CENPN MARCKS TUBGCP4 NF1 RACGAP1 DCTN4 SEC24B CDC23 ASF1B KDM6A YWHAE RABGAP1L RAB22A PTP4A1 CDYL PSMD10 RABGGTB AMD1 CDK1 CRKL TFDP1 SMC4 CBLL1 UBXN2B TYMS WDHD1 WHSC1 STK24 BIRC5 LARP4 NCAPH G3BP1 UBE2C TARDBP AZI2 EIF4A3 SNRNP27 H2AFY PTGES3 RAE1 CAND1 SFPQ BPTF TLK2 NCBP2 RAB7A SRSF1 PRKDC NUP153 SMC1A VBP1 RAB28 RRM1 SRSF2 DDX21 ADNP BUB1 USP9X PREPL SRSF9 CRY1 P4HA1 EFHC1 MNS1 WBP11 FANCI YTHDF1 SNRPD1 MTDH RRM2 HBS1L UBQLN2 PPP2CA DKC1 CDK2AP1 PAIP1 ATF2 SMS DBF4 HNRNPK HNRNPR CKAP5 ZNF318 RBBP4 PCBP1 ERCC6L FEN1 H2AFZ HNRNPH3 STRN3 SQLE HUWE1 WAC TRA2B KHDRBS1 SSRP1 HNRNPA2B1 MCM10 PHF10 ELAVL1 HSP90AA1 YBX1 EIF1 HNRNPU WRB COPS8 NDRG3 AZIN1 NFIB PAK2 CEP57 NONO SUMO4 CSE1L MLLT10 CCDC15 CCDC57 HNRNPD HMGXB4 ODC1 ARPP19 MEAF6 IFT81 KLHL23 RFC4 ZNF550 TSR1 BCL7A HSF2 CBFB NAP1L1 KLC1 CREB5 PNMA1 USP13 PNMAL1	0.000404215	DOWN
BENPORATH_PROLIFERATION	PBK APOBEC3B PDSS1 ASPM CEBPG MAD2L1 PRC1 CENPA TTK NEK2 CNIH4 AVL9 AURKA PRPF18 TOP2A DTL RIT1 RAD51AP1 CCNB2 COX5A CKS2 SRPK1 SLC25A5 CSTB LGALS8 EZH2 NDC80 TFRC PDCD10 CENPF CKS1B GGCT CDKN3 HSPA14 CENPE RAD51 CENPN PRIM2 UGGT1 RACGAP1 NFE2L3 PTS NDUFB5 CDT1 GPSM2 NMI KDELR2 MCM2 CDK1 PSMA3 TMEM14A TYMS NCAPG BIRC5 IDH2 PROSER1 SUV39H2 SMAD2 SPAG5 PTTG1 KPNA2 ARF1 ILF2 PCNA GART C1orf112 MSH2 CENPM BUB1 DEK GDI2 AGFG1 RBM8A SHFM1 DAP3 SNRPD1 CDC123 ANKRD27 MRPL9 LBR CSNK1G1 RRM2 TMSB10 HDAC2 DBF4 DIEXF H2AFV DTYMK ATAD2 SNRPG GTPBP4 PSMB4 H2AFZ FANCE TP53BP2 CHAF1B HRASLS WDR26 ASF1A PDCD5 RAD54L PKMYT1 EXO1 RANBP1 CSE1L GARS STMN1 FAM49B MCM3 RRAGD MAGOHB FAM3C S100A11 GINS3 MARCO FANCA PFDN2 MYBL2 S100A9 LRP8 RFC4 PARP1 A2M NCS1 RDX	0.00041667	DOWN
LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN	IL20RA FOXA1 KIAA1324 NAT1 SCGB2A1 TTC39A TOM1L1 AP1M2 PRR15L AGR2 CLDN7 TFF3 MYB VAV3 ABAT OVOL2 DHCR24 MYO5C CDH1 GRHL2 KRT19 KRT18 FXYD3 DACH1 CA12 SPINT2 SLC9A3R1 EPCAM PLEKHA6 EPPK1 TPD52 CEACAM6 ERBB2 ELF4 P2RY2 HRASLS2 MB EPN3 ZNF552 INPP5J BIK ZSCAN16 COX6C FRZB XBP1 ELL3 SCGB1D1 ACOX2 SCGB2A2 STK16 SPDEF AZGP1 DNAJC12 ESR1 REEP5 PIP SLC25A4 CST6 ARSD GSTM3 TBC1D9 NPDC1 DNALI1 AR SCGB1D2 RET SFRP4 GATA3 IFI44L NME5 LRRC17 ZDHHC11 PLA2G16 TRPS1 EFHD1 PTGER3	0.000424265	DOWN
REACTOME_RNA_POL_I_PROMOTER_OPENING	HIST1H2BC HIST1H4H HIST1H3H HIST1H3D HIST1H2AE HIST1H2BH HIST1H2AC HIST1H2BD HIST1H2BG HIST1H2BE HIST1H2BI HIST1H2BF HIST1H3E HIST1H2AJ HIST1H2BM HIST1H4K MBD2 HIST1H4B HIST1H3A MAPK3 HIST1H3F HIST1H2BK HIST1H4J HIST1H4D HIST1H2AD HIST2H2AA3 HIST1H4F HIST1H3B H3F3A H2AFX HIST1H4C HIST1H2BO HIST1H4L HIST2H4A HIST1H4A HIST2H2BE HIST1H3G HIST1H2BB HIST1H2BJ H2AFZ HIST1H4E HIST1H4I HIST1H2AB HIST1H3I HIST1H3C H3F3B HIST1H2BN UBTF HIST1H2BL HIST1H3J	0.000425003	DOWN
ZHENG_GLIOBLASTOMA_PLASTICITY_DN	CYR61 FOSB CRYAB TIMP3 CLU PCOLCE2 ITGA7 CAV1 RAMP1 ITGA5 PTGDS EMILIN1 COL4A1 COL6A2 ZFP36 THY1 CSPG4 DZIP1 MAPT EFS PGM5 ARVCF LPAR1 LSAMP SERPINH1 COL9A3 NISCH SYN2 MERTK EPHB1 RNASE1 KCNA6 PDLIM4 PVALB MXD4 ZDHHC14 CADPS TSC22D1 PCMTD2 BCL2L11 NDRG2 SORL1 FOSL2 PLAGL1 RDH5 ATP8A1 PPFIBP2 SLC26A2 TST PADI2 EMP1	0.000432686	UP
REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION	PCCA PCCB HADH ACADS ACADM DECR1 ECI1 MUT HADHA ECHS1 HADHB ACADVL ACADL	0.000433292	DOWN
EGUCHI_CELL_CYCLE_RB1_TARGETS	ECT2 NEK2 KIF11 CCNA2 CDC25C KIF20A NDC80 SMC2 CENPE CCNE2 MCM4 CDCA8 MCM2 KIF18A SMC4 NCAPG BUB1 MCM7 HMGB2 FEN1 MCM6 MCM5 MCM3	0.000433677	DOWN
INGRAM_SHH_TARGETS_UP	MGP CTGF AKAP12 THBD NR4A1 FILIP1L APOD TSC22D3 NID1 CYP1B1 PMP22 CLEC3B DUSP1 GRB14 PLTP DCN OMD CFHR1 FBN1 PENK OLFML2B CP IGFBP7 SPRY1 ARHGEF10 TEK SLC27A3 RAMP2 NR3C1 FMO1 MR1 TSPAN5 FLT4 ABCA3 ZFP36L1 AMH IGFBP4 TBX5 MFAP3L KLF10 IGFBP3 BDNF POMC PTK7 GLI1 SLC48A1 RORA KLF9 SLC6A6 NKX2-5 RASSF8 FOXD1 GPC4 MAP3K1 ALX4 AKAP4 DSCC1 RPL29 PTCH1 FEN1 MKNK2 DSPP CDC42EP1 LEPROT ASAH1 SERPINC1 FTL DNASE2B SLC12A7 ABCD4 IGF1R SLC35E3 UBE2J1 GADD45A EPHX1 NAA50 BZW2 OAT NGLY1 SOSTDC1 AFF4 DOCK5 ADD3 HEBP2 PRAMEF12 HES1 NCOA6 KLF4 ITPR3 NFE2L2 PAICS PLSCR1 TMEM140 TRIM10 ANKH FBN2 SULT1A1 PLAC8 GSTZ1 BMP5 ENPP1	0.000437089	UP
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR	ASPM PLEK2 E2F8 MAD2L1 WIPI1 HMMR PRC1 RFC5 CENPA TTK NEK2 KIF11 CCNA2 CEP55 MELK HMGB3 CCNB1 DLGAP5 TOP2A SQRDL BORA LXN KIF20A CDC20 CCNB2 HN1 RBBP8 SPC25 EZH2 TPRKB FGFR1OP FABP5 CENPF SMC2 DEPDC1 FBXO5 CDKN3 KIF23 LMNB1 PAICS NUSAP1 CENPN DCTPP1 RACGAP1 TOPBP1 KIF22 CDCA8 NEIL3 MCM2 CDK1 BIRC5 UBE2C DNAJC9 SPAG5 PTTG1 QSER1 NUP107 KPNA2 HAUS3 FAM64A PTTG2 PCNA CKAP2 H2AFX IFT20 BUB1 TIMELESS NUP88 LBR MCM7 EIF2S1 H2AFV DTYMK HMGB2 TDP1 USP1 KNTC1 CLN6 EXOSC8 LAMB1 CACYBP CDK2 RAD54L RPA2 EXO1 GPN3 RANBP1 POLD1 CSE1L NASP TRIP13 MCM3 KIFC1 MAGOHB E2F1 NCAPH2 GINS3 ODF2 MYBL2 MXRA5 SMPD4 SEMA3B RFC4 MDC1 FAM198B F10 SOD3 COLEC12 DCN FBLN1	0.000484477	DOWN
GREENBAUM_E2A_TARGETS_UP	ECT2 MAD2L1 CA2 KIF4A TTK KIF11 CCNA2 AURKA CCNB1 TOP2A SLC12A2 CCNB2 MKI67 FGFR2 PLK4 NUSAP1 SCIN KIF2C RACGAP1 PGK1 TYMS KLHDC2 H2AFX BUB1 EPRS EIF4EBP1 HS3ST1 CDKN2C PTGS1 SLC7A5	0.000493794	DOWN
HOEBEKE_LYMPHOID_STEM_CELL_UP	P2RY14 MN1 SCN3A TRIB2 SLC24A3 RAB31 SETBP1 BCL6 HLX DPEP2 BASP1 EVL ARHGAP25 TNFAIP2 RUNX3 RPS6KA2 PALLD ITGA4 TCF4 IQSEC1 BTK SH3TC1 PRKCB BAALC PLXND1 MACF1 TRAF5 NLRP1 C11orf21 ADA TRAF3IP3 TNFAIP3 STK32B SETD5 CHD3 LPIN1 SATB1 ITIH4 ITSN2 NCOR2 CYTH4 IRF8 MSL1 CCNL1 CCR9 PAPD7 LRRFIP1 TBCD MCM3AP METTL3 ABCA1 RBBP6 TRIM33 MEF2A NACA USP34 MED13L TPR RBM39 SF3B1 HNRNPA1 EIF4A1 KNTC1 TARBP1 SMARCA4 KDM3A ADAM28 OSBPL3 RERE ATR DDX21 PNN SLC38A1 TNS3 DOCK1 SLC2A5 TRAF4 UBR2 SLC35E2B NF1 TMEM41B RAB14 SPON1 SLC33A1 COBL	0.000500289	UP
RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_DN	SCG2 MLLT11 SFRP1 PRPH GAP43 INA TRIB2 KIF5C CHGB ISL1 RGS5 MAB21L1 GATA3 GATA2 RIMBP2 CRMP1 ENPP2 ELAVL3 APC2 MYCN DCX RENBP FEV CHGA DBH DLK1 TMOD1 CD24 DDC	0.00050074	UP
LIU_VAV3_PROSTATE_CARCINOGENESIS_UP	FABP4 TAC1 ADIPOQ AGTR1 TNC APOD BCL2A1 CFH FBLN1 NID1 CCL11 LTF FN1 SERPINA3 GPNMB SPP1 C3 GPX3 TGM2 USP13 PLA2G16 PLEKHB1 C1QA ACTC1 ITGB2 IGF1 CTSK ARHGDIB TYROBP LTBP2 ABCB4 CYBB TGFBR2 CDKN2C CD74 NOV LTC4S PLA2G7 LEP MME FCER1G EPHA4 MMP7 CCND2 TIMP4 HDAC9 TIMP2 HPR ARG1 RXRG CD1D IBSP FABP3 WFDC2 FUS GBP2 KLK3 TLR2 CD36 SIM2 SFTPD PSMB9 KRT7 STAT1 IFIT3 MBP PLAT TAP1 IRF1 EDNRB AMD1 SAT1 PSMB10 PSMB8 LGALS3 CASP1 CTSS TNFSF10 RNASEL SERPINB1 PLOD2 PPARG ITGB6 PITX2	0.00050417	UP
LANDIS_BREAST_CANCER_PROGRESSION_UP	EHF CMAS GALNT3 CLDN7 DSG2 IRF6 VDR FXYD3 SPINT1 WWC1 EBP AIM1 CHMP2B LSR TPD52 LITAF CLDN3 LCN2 SOX4 CYB561 ATP6V1A DAP XBP1 PQLC1 FAM134B ATP6AP2 SERP1 GOLPH3 ID2 KCNN4 SRP19 SS18L2 LRRFIP1 ELL2 CD82 NUCB2 ALDOC TFAP2C ACSL4	0.000508298	DOWN
ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN	CCNA2 AURKA CCNB1 TOP2A SCD CDC20 FOXM1 SPC25 CDC6 BUB1B TFRC CENPF HELLS CKS1B DEPDC1 PLK4 CDK1 ARHGAP11A WHSC1 BIRC5 BRCA2 G3BP1 MYNN POLE2 AURKB TOX4 RAD1 CD151 DBF4 DNA2 ERCC6L ACACA RANBP1 CHAF1A FUS MYBL2	0.000547352	DOWN
SENESE_HDAC1_AND_HDAC2_TARGETS_DN	MYL9 CRYAB TAGLN CALB2 BEX1 MFAP5 SDPR TIMP3 IGFBP5 CLU TNS1 TFPI CAP2 MN1 OLFML3 MEIS1 CAV1 LOXL1 NRXN3 SDC2 DUSP1 TUBA1A CALD1 TMEM100 TRIB2 GPNMB F8 SPP1 MYBL1 LAMB2 FSTL1 BNC2 COL5A2 LBH GLT8D2 S100A4 LTBP3 MYLK COL1A1 PLS3 PCOLCE FGFR1 RBMS3 KIAA0922 IGFBP7 COL16A1 TMEM45A LAT2 ARID5B LUM PPP2R2B AQP1 TCF4 PDGFRL SSBP2 DTNA FADS2 SCARA3 NACC2 CADM3 CELF2 ITGBL1 CDC42EP3 GPC1 SCN2B CDKN2C ZAK MSLN MATN2 STAC FGF1 DACT1 TNNT2 MAF COL3A1 GLI2 TPM1 ALOX5 SEMA3B EDIL3 NPTXR CSDC2 TGFB2 KRT81 NUPR1 RIN3 KRT17 TK2 PRR16 KRT15 RHOBTB1 ACADL SYT12 DSTN INSIG1 SET COL4A4 GSG1 ZNF362 CPA4 TCP11L1 NFIB ALDH3B1 TNNC1 SMAD6 ANXA10 PTCH1 SCEL SQLE JPH3 RNF187 SYNPO ATP8B1 THUMPD1 SPTBN1 UNKL NPPB KRT14 HDAC2 ZNF219 ZNF395 PDE1C CXCL14 ABLIM1 TNS3 HDAC1 MMP24 DHCR7 ELP4 C14orf1 EGF LOX PDLIM1 HIRA MTUS1 FDFT1 HAPLN1 LSS IDI1 ENDOD1 DEPDC1 WNT5A MSMO1 EDN2 RHOBTB3 MGST3 EPB41L3 ABCC3 TMEM135 QPRT PLCE1 SCD HIST1H2BD PLAC8 IFT74 SLC26A2 TUFT1 SYTL2 HIST1H2AC LRRC1 COQ2 WIPI1 SDC1 AP1M2 SRD5A1 PCLO HIST1H4H HMGCR IMPA2 KIAA1324 PKP2 OCLN	0.000547813	UP
REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS	PTPRC LCK HLA-DQA1 HLA-DPA1 HLA-DRB5 CD4 HLA-DRB1 CD3D CD3E HLA-DPB1 CD247 CSK CD3G	0.000558456	UP
WHITFIELD_CELL_CYCLE_LITERATURE	CENPA CCNA2 CDC25C AURKA CCNB1 TOP2A KIF20A CDC20 CCNB2 DHFR CKS2 CDC6 BUB1B PSRC1 CENPF CDKN3 CDKN1A RACGAP1 CCNE2 CCNG2 MCM2 CDK1 BRCA1 TYMS BIRC5 BRCA2 PCNA MSH2 RRM1 BUB1 NPAT RRM2 SLBP PLK1 CDC45 MCM6 E2F5 NASP CCNE1 CCNF E2F1 CDKN2D CDC25A CDKN2C	0.000585012	DOWN
NAGASHIMA_NRG1_SIGNALING_UP	CYR61 FOS FOSB EGR1 GAL CTGF NR4A2 GEM ATF3 FERMT2 TUBB6 EGR3 NR4A1 EGR2 RGS2 CXCR4 HBEGF NR4A3 DUSP1 KLF2 PPP1R15A DUSP10 BHLHE40 JUN TUBB2A MAFF PFKFB3 JUNB ZFP36 ZNF331 PER1 DUSP2 PALLD MAP3K14 GDF15 SRF GATA2 PLEKHO2 IER3 NAB2 ZYX IER2 EPHA2 CEBPB CDC42EP3 TRIB1 AEN HOMER1 FLRT3 SERTAD3 DUSP4 MYC DUSP5 USP36 AREG CLCF1 KLF10 TNFRSF12A FBXO41 ZNF365 LDLR SPHK1 ARC REL VCL SGK1 MAP3K8 PHLDA1 LRRC15 SEMA3B FOSL1 SNAI2 TGFB2 TES AQP3 DDIT3 PPRC1 KBTBD2 SOCS1 CGA MCL1 CCNL1 DLX2 KDM6B ZFAND5 KLF6 PLAUR DUSP8 SLCO4A1 PCF11 DST JMJD6 FBXL12 ISG20 LYPD3 EGR4 HIC2 PER2 ALOXE3 GADD45B WEE1 RARA MAP2K3 YRDC CAMK2G AKIRIN1 LIF TRA2B PMAIP1 SPATA2L TIPARP GTPBP4 IRS2 ARPC5L PSME4 PWP2 ITPKC CASP9 NDEL1 NPC1 ETS2 TOP1 CSNK1D GADD45A TNFRSF10B SFN VEGFA SERPINB8 CYP24A1 ID1 INPP1 TOB2 STK24 DNAJB1 EZR ADM ARG2 IFRD1 BCL10 PDLIM5 ID3 EIF5 HES1 FHL2 IER5 CTTN SPRED2 TNFRSF11B PHLDA2 EDN1 SPRR1B AVPI1 JOSD1 TNFRSF21 HERC4 NEDD9 EPPK1 FUT4 LAMC2 NFIL3 CLDN4 LAMA3 C3orf52 TUFT1 EGLN3 IL6R F2RL1 GATA6 FOXA1 CTH	0.000603581	UP
REACTOME_PD1_SIGNALING	LCK HLA-DQA1 HLA-DPA1 HLA-DRB5 CD4 HLA-DRB1 CD3D CD3E HLA-DPB1 CD247 PTPN6 PDCD1 CSK PDCD1LG2 CD3G	0.000606608	UP
LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES	ANK2 DNAJC6 INA MAP1B KIF5C CDK14 HMP19 MAP1A CHGB SNURF SNRPN NNAT NRGN IDS MMD MAP2 SLC17A7 GPD1 SULT4A1 BSN HPCA RPH3A KIFC1 EPS15 NECAB2 EEF1A1 TMSB4X MTCH1 RNF10 RAD51 ATP5B ACO2	0.000607578	UP
SANA_TNF_SIGNALING_DN	CTGF AHNAK2 LYVE1 SDPR PALMD CLU MMRN1 ANXA1 CRIP2 LDB2 EFEMP1 THSD7A TGM2 PEA15 EMCN PECAM1 KCTD12 VWF SASH1 PRKCH ARHGDIB RGS4 BGN CTNNAL1 GIMAP6 CD34 JAG2 DNAJB4 PPP1R16B AK5 IGFBP4 FAM198B SNRK PHLDA1 TM4SF1 NOS3 CALCRL PDLIM4 KDR PGAM2 TXNIP NFIB ANTXR1 ACE RPS3A MYOF TPT1 SRSF7 TXNDC5 KRT7 HTR1B CDK2AP1 ARL5A HDAC2 EPAS1 TMSB4X SMYD2 CCNA1 BMX ALDH1A1 CAPNS1 UQCR10 ANXA2 NT5E FHL2 ATP5A1 ATP1B3 PRKACB SSFA2 MTUS1 ARL6IP1 DDR1 ITGA6 KRT18 POSTN PCTP DHRS11 NQO1 GLCE	0.000611628	UP
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP	PBK APOBEC3B GGH PDSS1 ASPM XK ECT2 AMMECR1 HPGDS E2F8 MAD2L1 KIF15 SLC25A13 HMMR PRC1 CEP76 CENPA KIF4A HIST1H1C TTK NEK2 GMNN ABCD3 TST ELOVL6 KIF11 MINPP1 CCNA2 SUCLA2 CEP55 AURKA MELK SFXN1 CCNB1 DLGAP5 OIP5 GINS1 TOP2A STK39 KIF20A ZWINT CHEK1 MRPS28 CDC20 RAD51AP1 CCNB2 LRRC59 SORD DHFR TPX2 ATP5G3 ABCC4 SPC25 CDC6 EZH2 NDC80 BUB1B PPIF FABP5 CENPF KIF18B CLC CKS1B CDC7 SMC2 FBXO5 CDKN3 HSPA14 KLHL7 RAD51 NUSAP1 CPOX KIF2C PDLIM1 RACGAP1 CCNE2 RNASEH2A ESPL1 PRDX2 KIAA0101 ACOT7 GINS2 MICAL2 MCM4 SAC3D1 MCM2 CDK1 BRCA1 TYMS SAMM50 TK1 NUP85 NCAPG BIRC5 GSPT1 IDH2 PRDX4 RPA3 UBE2C PF4 LSM5 POLE2 SPAG5 AURKB KPNA2 RFC3 MRPS15 CENPM RRM1 H2AFX BUB1 ITGB3BP FANCI SNRPD1 RRM2 HAT1 RNASE2 SNRNP25 VRK1 SYNCRIP EIF1AX SUB1 FEN1 MCM10 DNAJC12 SERPINB2 LMNA CDC45 ARHGAP19 MPO SHMT2 UBE2S DSCC1 RHAG MCM5 DUT RANBP1 CSE1L ZNF593 CD36 STMN1 CCNE1 TRIP13 CST7 NUDT1 AQP3 PRG2 ITGA2B NPM3 HBD CPA3 KLF1 MS4A3 RFC4 TPM1 HGF CLEC11A TFR2 TPSAB1 HDC PIEZO2 PPBP SLC7A5 PROS1 TPSB2 PRKAR2B NT5DC2 ACTN1 CSTA RAB31 HBB LEPR PMP22 DLC1 CCL2 TUBB6	0.000636883	DOWN
YANG_MUC2_TARGETS_DUODENUM_3MO_DN	UGT2B17 CYP2B6 FMO5 SULT1B1 NQO1 GSTM4 EPHX2 POR CAT ME1 GSTK1 CYP3A43 NFE2L2 GLRX GSTM1 CYP4A11 SULT2B1 GSTA4 CYP1A1 GSTT1 GSTM5	0.000641168	DOWN
WEST_ADRENOCORTICAL_TUMOR_MARKERS_DN	FOSB GAS1 NR4A2 MFAP5 ADH1B IGFBP5 FBLN1 C3 DCN RARRES2 LSP1 NOV WNT4 CYP11B2 PDGFRA AADAC KCNQ1 VSNL1 SPON1 HSD3B2	0.000646959	UP
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP	AHNAK2 DES CRYAB REEP1 TAGLN CASQ2 PALMD TNS1 SMPX CHODL PTRF RGS2 WWTR1 ACTA2 NCAM1 HBEGF FHL1 LDB3 QKI AEBP1 PYGM TGM2 DCN C1R COL6A3 HSPB2 SCN3B PDLIM7 COL1A1 SGCD MYOM1 COL16A1 TNFAIP2 LAT2 CX3CL1 ARHGEF6 ITGB1BP2 FAM131B EFS MAPK10 HCFC1R1 TPD52L1 PNOC DMPK GNAI2 MACF1 SST GPR37 CTF1 TRAF5 RASSF4 ABLIM3 RUSC2 PLEK GNAO1 MRAS MYBPC2 PRKCQ IGFBP4 OSBPL10 MYL6B SPN BIN1 SGCG TNPO2 MEF2C ARMC9 DTX3 LRTM1 ACHE PBXIP1 TPM1 MEF2D GSTA1 RARB BBS9 TP63 KLF1 FYB ALDH1A2 EHBP1L1 UTRN PRRX2 BICD1 SRGAP3 C21orf62 NENF ADAM8 SFSWAP ISG15 CCR5 CYP2W1 FABP3 MYH3 CALCRL SOHLH2 TAOK2 TNNT3 STK10 MAPRE3 AGRN PAPPA2 TNNI2 APOBEC2 DCX MYBPH TXNIP KLF6 MYL4 DOK1 AQP6 ASCC1 FER MYLPF ADAM30 MYL1 CD36 CAMK2B RBM17 BCAN RANBP3 HIVEP3 SLN ATP6V0A4 GRIN1 RANBP1 CELA3B CDC42EP2 PLA2G3 GADD45B MYH8 ATF7IP2 RSPH6A MTSS1 ANKZF1 TNNC1 MUC3A MKRN2 TTC3 CXCL10 LIF TEAD4 ACBD4 MYBPC1 EPS8L1 ARSF MAPK7 CLSTN2 SPDEF IRGQ GHRHR SPAG6 GMEB1 SYNGR2 TNNI1 CACNB1 MYH1 ACSL1 RBM8A ING4 AK1 VARS PAN2 H2AFX ADAP1 NEBL PARP3 TNNC2 HLA-A IL32 C2CD2L CASP10 EZR PDLIM5 GPRIN2 PDE4DIP AKAP1 FOSL2 SLC24A1 AMPD1 DNAJC7 ATP2C2 AGL XRCC4 FAM13A EPB41L3 ITGA6 XIAP SLC12A2 SCD SERPINB1 HRH1 INPP4B HSPB3 ACAA2 NOX1 GJB1 MYO10 EGLN3 TUBAL3	0.00065116	UP
FINETTI_BREAST_CANCER_KINOME_RED	PBK TTK NEK2 AURKA MELK CHEK1 SRPK1 BUB1B CDC7 PLK4 CDK1 AURKB BUB1 VRK1 PLK1	0.000720344	DOWN
DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER	CMAS KBTBD11 CEBPG AKAP9 NEK3 MIPEP MRPS28 PPM1A FBXO3 SDHC TPD52 CDK8 KIAA0196 MFN1 RAB20 NAPG GATAD1 PDCD6 VPS41 BRWD1 PRKCI GABPA SNAP29 PEPD COG5 MRPS11 GEMIN2 CTTN NDUFB5 PPFIA1 ATP11B CBLL1 SEC23IP PPP4R2 DCAF13 SIAH2 MYNN KRIT1 SENP2 H2AFY RB1CC1 VPS8 WHSC1L1 RAE1 TXNL1 METTL4 MTMR6 RASA1 NUP153 FBXW11 RYK FIG4 ZNF302 CHD7 GOLGA7 ANKRD46 TAF2 DBR1 ANKRD10 ARMC1 LSM1 THUMPD1 ASH2L E2F3 NIPBL TERF1 ING1 DCTD MAPK8 KPNA4 IPO8 TBCA DNAJC2 EIF3H PAK2 BAG4 THOC1 MAP3K1 ARMC8 PHC3 PIK3CA GTF3A RFC4 PPP1R12A FXR1	0.000723095	DOWN
KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN	SCRN1 GPX7 RASSF2 MS4A1 CD79B KIAA0922 SH3BP5 CD19 VNN2 CD79A BTG2 FAM65B HLA-DQB1 CD52 GATM CD27 CTSH NCF4 HLA-DMA CD72 ZHX2 CD22 TRAF5 FADS3 CXCR5 SWAP70 SIT1 HLA-DMB MMD CD40 PTPN6 BCL11A ETS1 LRMP SPIB PKIG IRF8 BIRC3 MAPRE2 POU2F2 AES MSL3 ST6GAL1 STX7 SYPL1 GSTP1 DEK SEL1L3 PAWR ID3 CAPG BLNK DBI ALDH5A1 CD24 CCDC6 BCAR3	0.000724873	UP
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP	FOS FOSB NR4A2 FGF13 TSC22D3 RGS2 GPR183 SERPING1 AP1S2 HBEGF CFD DUSP1 KLF2 MXRA7 DENND5A ATP2B4 PTGDS RBMS1 PLCB1 TCL1A PLA2G16 JUN ZFP36 EVI2A IGFBP7 CHST11 ARHGAP25 PER1 CSGALNACT2 ALCAM TIMP1 VAMP1 ST3GAL5 GLIPR1 CEBPD CFP CECR1 SAP30 MRC2 CD3D NLRP1 TRIB1 CD44 HCAR3 GABRE STAB1 KLF10 CD8A FLT3 HGF AAK1 TCFL5 N4BP2L1 PTPRO PRKCA NFKBIA CD96 SIN3B PLSCR3 NDE1 IDUA CD33 KIAA0754 SIK3 BTG1 ZFAND5 KLF6 TLR2 BCL11B AGTPBP1 PRF1 PLEKHA5 ABCA1 GNLY SPRY2 AFF2 CTSW HELZ HIC2 UBE2D4 SF1 GFI1 NACA RPL13 ATP6V1G1 MED13L DRG1 NDST2 NRIP3 LONP2 HAL KAT6B COL4A5 ANKS1A TANK HNRNPH1 IRS2 ID2 MRPL33 ZNF273 SPSB3 TRAM1 HIST2H2BE TOMM20 NFYA SPEN JAG1 ITM2B ZMYM2 PDE3B MAP1LC3B ZNF185 S100P CCNA1 SIPA1L1 TGOLN2 ZBTB43 CBLB ZNF264 CITED2 SMURF2 TPBG PSMA1 UBB XBP1 AZI2 STK17B RNF11 FNDC3B PTPRE HIST1H2BK GLRX SORL1 TCF7L2 MYLIP ARL4A AUTS2 WDFY3 SMC5 ZFAND6 DMXL2 ZNF91 WNT6 PLAGL1 NCOA2 ATP1B1 NDUFS4 SLC31A2 LY75 MGST3 MRPS30 TRAPPC10 RAP1GAP2 TMEM131 NFIL3 KRT18 ABHD3 WASL	0.00072705	UP
BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN	EGR1 FERMT2 ACTA2 QKI AMOTL2 COL5A2 NRP1 VCAM1 COL4A1 PDLIM7 SPARC ACTC1 COL4A2 WWC2 IER2 NR2F2 LPP TPM1 VCL CSF1 SSB ROCK1 KLF6 WSB1 SF3B1 KAT2B STRN3 UGCG MYH9 LUC7L3 HSPA5 FASN IGF1R ATXN2 PRSS23 PPP1CB XBP1 DOCK5 EXT1 PAWR SH3GLB1 WSB2 F3 KLF5	0.000737536	UP
REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	TNC FN1 SPP1 ITGA5 LAMB2 JAM3 ITGA1 JAM2 FBN1 LAMC1 VCAM1 COL4A1 ITGAM COL1A1 COL1A2 PECAM1 ITGB2 ICAM2 LAMA2 VWF COL4A2 RASGRP1 TLN1 LAMA5 ITGAL RAPGEF3 ICAM1 RASGRP2 ITGA9 ICAM4 LAMA1 FGB ITGAX ITGB7 APBB1IP ITGA2B IBSP COL2A1 RAPGEF4 AKT1 COL4A4 FGA ITGA8 ITGA10 ITGB8 ITGB1 ICAM3 CSK PTPN1 ITGB3 LAMB1 RAP1A PTK2 COL4A5 SHC1 PDPK1 ITGAE VTN GRB2 RAP1B ITGA3 FGG ITGAV COL4A3 ITGB5 SRC SYK THBS1 ITGB4 SOS1 CRK ITGA2 CDH1 F11R BSG ITGB6	0.000740088	UP
LEI_HOXC8_TARGETS_DN	GAS1 CNN1 TAGLN GREM2 ACTA2 NCAM1 SPP1 ADAM19 ELMO1 SERPINF1 CXCL10 ANKRD1 ASS1 PLAGL1 KRT19 NQO1	0.000742117	UP
KANG_IMMORTALIZED_BY_TERT_DN	OGN ZFPM2 THBS2 EGR3 CCL2 NR4A1 TGFBR3 CXCR4 THBS4 NR4A3 PMP22 ADAM19 SERPINI1 PRELP NRP1 MMP9 DNM1 HTR2B FGFR1 RGS5 CNR1 SH3BGR TYRP1 ARHGEF6 WISP2 CD52 PPP2R2B INSL5 MAFB ALDH1A3 RASGRP2 GHR A2M TSPAN5 SVIL CDH2 PDE4D CD44 PTGS1 TNFAIP3 ST3GAL1 SPN TFR2 GFRA3 ACHE NTRK2 NPFFR1 MOBP GRM7 TFPI2 KLK14 IMPG2 ADAM20 SERPINA10 KLF9 MSX2 DLX6 E2F1 GLUL MMP3 OPRL1 ADAMTS3 SNTG2 ABCC9 GPR88 ST8SIA5 PDE10A PRB4 CHST1 RGS12 GCGR ZNF236 GABRR1 FSHR PRM1 MYH4 CALCA ZFX CKB MYH2 MYH1 ZNF141 EFNA3 DHRS3 MAP2K2 NET1 ACYP1 NPY1R MGLL RAD23B RDH5 TWF1 CASP1 ATP9A SMG1 MMP1 NOX1 TMPRSS4 MYO1D ADH1C	0.000744743	UP
MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP	FOS EGR1 GEM CCL2 TNC MMP9 COL6A2 THY1 CTSK COL6A1 PDGFRB FGR RAB3B TMEM156 PLAU KRT17 TCN1 PDGFA CA12 FXYD3	0.000749456	UP
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN	MRPL19 SLC16A1 MINPP1 AVL9 PPIP5K2 ABHD3 ZCCHC10 TDP2 IFT74 CHEK1 SPATA5L1 TMEM135 SLC33A1 RNF7 KLF13 STAM2 MET MRPS12 NCLN ZNF277 PEX1 AIMP2 ACTR6 FANCL DNAJB14 FANCF EZH2 MPHOSPH9 NNT ORC5 PDCD6 GCSH SPAST RACGAP1 WDR61 CDC23 IFT57 NADSYN1 EBNA1BP2 RSF1 C1QBP LSM4 MYLIP BTBD1 IREB2 MCM2 CDK1 PSMA3 PSMC4 TYMS PSMD8 PAPOLA G3BP1 KRIT1 LSM5 ACTL6A IP6K2 NAA50 AASDHPPT SLC38A1 CCT5 PFDN4 ATP5L COMMD4 DHX29 FAM188A RNF111 TMEM165 NCAPD3 KEAP1 PRKDC RPL26L1 ANKRD49 DENND4A NDUFA13 SNX19 RUVBL2 CHMP4A FIBP CYP2R1 FEM1B LEMD3 LAP3 SHFM1 SNRPD1 BUB3 TAF2 DKC1 PAIP1 SLC25A36 DDX1 DBF4 THYN1 CCDC94 CCT2 EIF3M SMARCA4 TERF1 UPF3A SSBP1 IK NOL8 MINA LRRC40 ASF1A PPP2R5C SF3B2 GLT8D1 IARS ERCC1 RAN DDX31 CEP57 TIMM50 MATR3 ELAC1 PAK1IP1 MBD4 NASP TBCB NMT1 DARS MCM3AP PAAF1 CEP152 DDX18 ZNF131 RFX7 TLE4 EIF3G ANAPC10 ILF3 PPP1R12A BARD1 ACD TRIB1	0.000754787	DOWN
MAHADEVAN_RESPONSE_TO_MP470_DN	CYR61 CRYAB GEM ATF3 DUSP1 PPP1R15A BHLHE40 MAFF GDF15 HSPA6 MYC DUSP5 DDIT3 KLHL24 GADD45B HSPA1A CTTN SOD2 NFIL3	0.000785369	UP
INGRAM_SHH_TARGETS_DN	AOC3 GPM6B CLU SFRP1 CAV2 TPPP3 TUBA1A C3 EREG COL1A1 EVL SPARC LRRC17 PGM5 MAGED2 DRAM1 SLC1A3 RET WNT5B PTN DIRAS2 BAMBI ANGPTL4 MME GNA12 CRLF1 TGFBI HGF ITGB7 C2orf68 BRPF1 POU3F1 CALCRL DAXX CCNE1 GAS6 SND1 VCAN IL1RN TYK2 OR2S2 CDC37 PTX3 PRDX4 GLRX PLK4 ENDOD1 SLPI PPM1D SDC1	0.000788781	UP
REACTOME_NCAM1_INTERACTIONS	NCAM1 COL5A2 PRNP COL6A3 COL4A1 COL1A1 COL6A2 CACNA1H COL1A2 COL4A2 COL6A1 NRTN GFRA2 ST8SIA4 COL5A1 ST8SIA2 CNTN2 COL9A3 COL3A1 GFRA1 CACNB2 CACNB4 ARTN COL9A2 COL9A1 AGRN COL2A1 PSPN CACNA1G GFRA4 COL4A4 GDNF CACNA1I COL4A5 CACNA1S CACNB3 NCAN CACNB1 COL4A3	0.000790455	UP
KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION	CXCR4 CXCL12 TGFB1 HLA-DOB HLA-DQB1 AICDA HLA-DQA1 MAP3K14 ITGA4 HLA-DRA CCR10 TNFRSF13B HLA-DPA1 HLA-DMA ICOS HLA-DRB5 CD86 IL6 HLA-DRB1 HLA-DRB4 HLA-DMB HLA-DPB1 CD40 CD28 MADCAM1 ITGB7 CD40LG CCL27 CCL25 CCR9 IL10 HLA-DOA IL5 CD80 ICOSLG TNFRSF17 IL15RA LTBR IL2 IL4 TNFSF13 IL15 PIGR	0.00079359	UP
BIOCARTA_CCR5_PATHWAY	FOS CCL2 CXCR4 CXCL12 JUN PRKCB CCL4 PLCG1 PRKCA CCR5 PTK2B MAPK8 CALM1 CALM3 CALM2 GNAQ MAPK14	0.000798498	UP
GESERICK_TERT_TARGETS_DN	FOSB NR4A1 EGR2 HBEGF BHLHE40 ELN JUNB ZFP36 BTG2 IER3 DUSP6 KLF10 KLF9 GADD45B HEY1 GADD45G SIAH2 KLF4 NFIL3	0.000812795	UP
REICHERT_MITOSIS_LIN9_TARGETS	ASPM HMMR CENPA CEP55 AURKA MYO6 CCNB1 TOP2A KIF20A MKI67 CENPF FBXO5 CENPE KIF23 NUSAP1 KIF2C NCAPD2 VCPIP1 HMGB2 CDK11B PLK1 ANAPC1 CCNF CALD1	0.00084258	DOWN
PID_SYNDECAN_4_PATHWAY	TFPI TNC CXCR4 CXCL12 FN1 FZD7 ITGA5 MMP9 FGFR1 ACTN1 FGF2 TNFRSF13B LAMA1 PRKCA FGF6 MDK ITGB1 ADAM12 F2 CCL5 PTK2 SDCBP RHOA GIPC1 PLG RAC1 THBS1 SDC4 PRKCD DNM2 LAMA3	0.000877422	UP
ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN	GEM CAV2 PPP1R3C AXL CYP1B1 VEGFC DUSP10 CCL3 JUN TUBB2A TNFRSF9 FGF2 ANXA5 ZFHX3 NCF2 GATA3 RAPGEF3 CCL4 PPP3CC PTHLH SERPINE1 ADORA2A IRF5 PLK2 AHR RALGDS IL2RG CDC14A RGS20 CXCR3 IFNB1 RANGAP1 TRAF2 FOXO3 TUBA4A CTSE YAF2 CFLAR PTGER2 AADAC UBE2D3 SOCS2 TFDP1 ARL4A ITPR3 SMAD1 IL15 RRAS2 MAP4K5 ATP2B1	0.000884811	UP
ELVIDGE_HYPOXIA_BY_DMOG_UP	FOS EGR1 AHNAK2 SRPX AKAP12 ATF3 IGFBP5 ENO2 CSGALNACT1 CXCR4 CAV1 SPOCK1 ITPR1 VEGFC CSRP2 SAMD4A OBSL1 KLF7 BHLHE40 CADM1 BNIP3 S100A4 LIMCH1 SFXN3 TMEFF1 JUN MAFF PFKFB3 OLFML2A FYN PAM TMEM45A SPRY1 WISP2 TNFAIP8 GDF15 DDIT4 DTNA NR3C1 HLA-DRB1 STC1 ANGPTL4 GJA1 SERPINE1 STC2 TGFBI IGFBP3 PIM1 ALDOC PRKCA PHLDA1 INHA DAAM1 LOXL2 ZNF292 YEATS2 RLF ARTN KLHL24 SPAG4 TXNIP RRAGD KLF6 ATXN1 DPYSL4 PLAUR SLCO4A1 DST ISG20 PPFIA4 WSB1 GYS1 PFKP HEY1 CA9 SCNN1B BNIP3L S100A2 QSOX1 KDM3A ZNF395 YPEL1 P4HA1 CD59 ATG14 CITED2 SRD5A3 INSIG2 VEGFA AK4 S100A6 PDK1 GPR87 GLRX ADM RBCK1 ANG PGK1 SAT1 RNASE4 CYB5A EGFR SLC2A1 CCNG2 LOX ILVBL MXI1 FAM162A ELF3 FAM13A P4HA2 GBE1 SOX9 VLDLR MET NDRG1 ASPH STBD1 PLAC8 OPN3 NFIL3 PGM1 HK2 EGLN3 EGLN1 DSC2 ADORA2B	0.000899332	UP
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	GAL RGS1 P2RY14 PTGER3 CCL21 ANXA1 CXCR4 CXCL13 CXCL12 CCL19 CCR7 C3 GABBR1 P2RY13 PENK S1PR1 GNG11 CNR1 CXCL2 GNB5 GNG3 RGS4 INSL5 C5AR1 PNOC ADCY2 CCR10 RGS19 GNAI2 GNAZ RGS9 SST CCR6 GPR18 C5 ADCY7 PPBP CXCR5 CXCL1 CCR1 CCR2 SSTR5 HCAR3 LPAR1 CCL20 CCR4 FPR1 C3AR1 GALR2 GALR1 NMUR1 GNG7 S1PR4 MTNR1B POMC NPY2R HTR5A NPBWR2 CXCR2 OPRD1 APLNR RGS11 SSTR4 ADCY3 OPN1MW CCR5 CCL27 HTR1E ADCY8 RGS6 CCL25 HRH4 CXCR6 AGTR2 PPY OPRK1 CCR9 HTR1A GNB3 ADORA1 CNR2 HTR1D CCL16 OPRM1 ADRA2B OPRL1 CXCL9 NMU RGS20 P2RY4 HRH3 GABBR2 GNAS RLN3 CXCR3 FPR2 CHRM2 OPN1SW GPR17 RHO HTR1F RGR RGS12 RGS7 S1PR5 S1PR2 CXCL3 SSTR1 GNG4 CCL5 SSTR3 DRD2 GNB1 ADCY1 CXCL10 GNAT2 GNG13 FPR3 CCR3 MCHR1 PDYN ADORA3 GNAT1 DRD3 CCR8 RXFP3 BDKRB2 HTR1B LPAR2 PMCH CXCL5 GNB2 MTNR1A NPY5R BDKRB1 SSTR2 CXCR1 GNGT1 CASR GALR3 LPAR3 HEBP1 APP PF4 GNAI3 PYY KNG1 RRH GNG5 CXCL11 CXCL6 ADCY9 NPY1R NPY ADCY6 GNG12 OPN3 ADRA2A GNAI1 AGT	0.000904591	UP
PID_INTEGRIN_A9B1_PATHWAY	TNC FN1 VEGFC SPP1 F13A1 TGM2 VCAM1 ITGA9 CSF2RA ADAM8 PAOX CSF2 ADAM2 ITGB1 ADAM12 NOS2 KCNJ15 ADAM15 PXN SRC VEGFA RAC1 SAT1	0.000998963	UP
LINDVALL_IMMORTALIZED_BY_TERT_UP	ADAMTS1 UCHL1 CAV1 FHL1 EFEMP1 CALD1 FZD7 ELOVL5 EHD3 COL15A1 EREG RGS10 IGFBP7 FOXF2 NES LUM PGM5 ARID5A PDE5A A2M WNT5B TSPAN5 PTN MDFIC PTGS1 ST5 STC2 ARMC9 SLC38A2 FRMD4A NAB1 TRIM28 GSTT1 TRIOBP POMT1 FKBP11 DKK1 ARPC1B SLC6A8 BMP4 TAPBP SKIV2L2 VAMP3 USP53 ATP6V0A1 CTSZ CITED2 HMGA1 PELI1 ASS1 KDELR3 PAX8 EXT1 IGF2R WDR37 ANXA11 RPS4Y1 FDFT1 BBS7 CD9 ATP2B1 KRT18 PAPSS2 SLC22A18	0.00106066	UP
ABE_INNER_EAR	MGP ATP1A2 CLU DDR2 LHFP APOD IGFBP6 ISLR PTGDS PLEKHB1 PCDHGC3 USP11 COCH ZBTB20 RBP1 MIA VAMP5 OTOR COL9A3 TMX4 S100A13 NENF C19orf53 COL9A1 DGCR6 CA14 FOXD1 UBXN1 UBA52 LRP1 RPL35 RPS5 RPS11 RPL32 RPS15 HYI RPL21 RPL28 MT3 CCS UTY ZP2 RAB1B CRYM USH1C	0.00110947	UP
YANG_MUC2_TARGETS_DUODENUM_6MO_DN	UGT2B17 CYP2B6 REG1A FMO5 NQO1 GSTM4 EPHX2 POR CAT ME1 GSTK1 CYP3A43 NFE2L2 GSTM1 CYP4A11 GSTA4 GSTT1 FMO1 GSTM5	0.0011384	DOWN
NADERI_BREAST_CANCER_PROGNOSIS_DN	TGFBR3 FBLN1 DCN OMD SPARCL1 C1S ANXA5 CEBPD IFT81 TXNIP REXO2 SSR2 NANOG CLDN1 CLK4 SHOX2	0.00121227	UP
HUANG_FOXA2_TARGETS_DN	SRPX TNC CRIP2 LEPR IGFBP6 SPP1 ATP2B4 TGM2 S100A4 SPARC CXCL2 COL6A1 PROS1 SSBP2 CD44 TGFBI CDH3 LOXL2 COL13A1 CFI KRT81 PLAUR CLIC3 GALNT6 STS GAS2L1 ST6GAL1 SMAD6 CTSB SCEL ACOX2 PLAT ITGB4 CDKN1A STEAP3 CEACAM1	0.00122952	UP
KEGG_CELL_ADHESION_MOLECULES_CAMS	NFASC NRXN3 NCAM1 SDC2 CDH5 SELL CADM1 NLGN4X JAM3 JAM2 VCAM1 ITGAM NRXN1 SDC3 HLA-DOB PECAM1 ITGB2 PTPRC PTPRM ICAM2 NRXN2 ALCAM HLA-DQB1 NLGN1 HLA-DQA1 ITGA4 HLA-DRA HLA-DPA1 CLDN5 ITGAL HLA-DMA CD2 ICOS ICAM1 HLA-DRB5 CD86 SELP CD4 CD34 CD22 HLA-DRB1 CADM3 CDH2 HLA-DRB4 HLA-DMB HLA-DPB1 CD40 CNTNAP1 CNTN2 SELE ITGA9 MPZ CD28 SPN CLDN10 CNTN1 MADCAM1 L1CAM CD6 CD8A ITGB7 CDH3 CD40LG SELPLG CDH15 CTLA4 CLDN11 CD226 CLDN17 CLDN9 SIGLEC1 PDCD1 CLDN6 MAG CD8B CD99 CDH4 NLGN3 HLA-DOA ITGA8 VCAN NCAM2 ITGB8 ITGB1 ICAM3 CLDN14 CLDN16 PVR CD80 ICOSLG GLG1 CLDN18 NRCAM PDCD1LG2 CNTNAP2 CLDN1 ITGAV HLA-E HLA-C HLA-G HLA-B HLA-A HLA-F SDC4 MPZL1 CLDN15 CD58 CLDN3 ITGA6 PTPRF CLDN8 CLDN4 NEO1 CDH1 F11R CLDN7 SDC1 OCLN	0.00132902	UP
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	GAL TAC1 CCL2 AGTR1 CCL21 EDNRA ANXA1 CXCR4 CXCL13 CCL11 CXCL12 CCL19 CCR7 C3 TACR2 PENK CCL3 CXCL2 CX3CL1 CCL22 INSL5 C5AR1 PNOC CCR10 SST CCR6 CCL4 CX3CR1 C5 PPBP CXCR5 CXCL1 CCR1 CCR2 PRLH SSTR5 INSL3 CCL20 CCR4 FPR1 CCKAR NTSR1 C3AR1 MC1R CCL17 AVPR2 GALR2 GALR1 NMUR1 NPFFR1 POMC NPY2R NMB GRP TACR1 NPBWR2 CXCR2 OPRD1 APLNR UTS2 SSTR4 NPFF AVP CCR5 HCRTR2 OXT XCR1 CCL27 TRH XCL2 CCL25 NTS CXCR6 HCRT KISS1 AGTR2 PPY MC3R OPRK1 CCR9 MC4R OXTR TAC3 MC2R BRS3 CCL16 OPRM1 OPRL1 GAST CXCL9 HCRTR1 NMU GHSR GRPR RLN3 CXCR3 FPR2 CCK CXCL3 SSTR1 F2 CCKBR F2RL3 XCL1 F2RL2 CCL5 MLN SSTR3 NTSR2 CXCL10 MLNR AVPR1B FPR3 CCR3 MCHR1 PDYN CCR8 CCL7 RLN2 AVPR1A RXFP3 BDKRB2 PMCH CXCL5 NPY5R BDKRB1 SSTR2 CXCR1 TACR3 GALR3 HEBP1 APP NMBR PF4 PYY KNG1 F2R TRHR EDNRB MC5R CXCL11 CXCL6 NPY1R NPY EDN1 EDN2 EDN3 AGT F2RL1	0.0013305	UP
DAUER_STAT3_TARGETS_UP	AKAP12 ATF3 CCL2 SAMD4A C3 KLF11 HEG1 BCL6 JUN GFPT2 MAFF PFKFB3 ZFP36 PALM2-AKAP2 ICAM1 SLC2A3 CEBPD SOCS3 TRIB1 DUSP5 SLC4A7 LBP SLC2A14 FGB LDLR FOSL1 STAT2 ABCA1 FGA SERPINB3 STAT3 CTSB TEAD4 UGCG BCL3 FGG NPC1 IGFBP1 SFN THBS1 ADM SOD2 PLIN3 EFNB2 FLNB EFNA1 FEM1C AGT	0.00133929	UP
KIM_WT1_TARGETS_8HR_UP	ATP1A2 PEG3 GEM TIMP3 TNS1 ENO2 TGFB1I1 ID4 BCL2A1 PLEKHO1 WWTR1 HBEGF PCDH7 SYNE1 QKI ADAM19 DNAJB5 RHOQ EREG JUN PEA15 GFPT2 MAFF FGFR1 JUNB CSPG4 PODXL SH3BP5 SIRPA ACTN1 CX3CL1 GRB10 RGS4 PIK3CD CDR2L PLXND1 ZYX HSPA6 DNAJB4 FAM65A CHST3 DAB2 CBFB DUSP7 SWAP70 TRIB1 PTHLH DPEP3 PDGFC SERPINH1 ST3GAL1 AREG SERPINE1 FGF1 MARK4 KLF10 IL6ST SPHK1 ARC PIM1 DOK5 FHOD1 BTG3 SUPT6H LYN TM4SF1 BAIAP2 CSDC2 FOSL1 SNAI2 B4GALT6 WT1 RLF CSF1 PDLIM4 EIF5A HNRNPL MICALL1 IL11 DLX2 TPST2 ULBP2 DARS PLAUR RSL1D1 WWP1 SRSF6 PDE10A PLEC WSB1 DICER1 SERTAD2 ZMYM6 METAP2 PIAS2 FOLR1 HSP90AA1 PURA MAP2K3 HNRNPUL1 SON IL4R ARHGDIA MTMR1 KPNA6 GTPBP1 SRP72 STRN4 MKNK2 TUBA4A RYBP PA2G4 SPEN IL1RAP KHSRP LEPROT ZC3HAV1 HSPH1 PPP3CA AFF1 SLC7A1 RBM8A NBL1 HSPA1A HIPK1 TOP1 ZMIZ1 SEL1L ERGIC2 SFN TPBG AHCYL1 HMGA1 IVNS1ABP DNAJB1 SNAP23 GLRX ADM NAA15 BMPR2 RHOF SPRED2 CREB3L1 SYNJ2 PRKCD PHLDA2 RAB14 RAB40B SOX9 DOK4 ATP2B1 SLC20A1 CA12 ATP9A GOLIM4 ABHD3 TBC1D2 LAMB3 ABAT NLK EMP1	0.00134661	UP
WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2	GAL TIMP3 KCNN3 MAP1B CAV1 AXL ADAM19 CRISPLD2 JUN SDC3 PODXL NTM TEK ITGA4 IL7R MICA CCND1 ABLIM3 COL5A1 PTHLH BCL7A INHBA CDK6 PAPPA TPM1 MMP7 NAV2 FOSL1 MICALL1 LFNG PLAUR CPA4 ITGB8 MICB RHOD MYOF S100A2 SAFB2 KRT75 BMP1 ITGA3 CLDN1 DNMT3B GADD45A PLAT ADM NET1 MICAL2 EDN1 P4HA2 BMP5 F2RL1	0.00134815	UP
ONDER_CDH1_SIGNALING_VIA_CTNNB1	MYL9 GREM1 TAGLN FERMT2 AGTR1 MAP1B ACTA2 SPOCK1 KCNMA1 FBLN5 C3 SCG5 PRRX1 FBN1 COL6A3 PRUNE2 COL1A2 IGFBP7 PODXL CXCL2 ADRB2 MAGEH1 DOCK10 LMCD1 BEX4 BGN ARHGAP22 PPL CD83 ICAM1 LTBP2 CADM3 CDH11 CXCL1 AOX1 TNFAIP3 FZD3 SERPINE1 BIN1 STC2 MMP19 IGFBP3 TPM1 LTBP1 MFAP2 NUPR1 BIRC3 CD82 VCAN IL17RC MIOS CREG1 EPAS1 SYBU KCNJ6 PELI1 KDELR3 EPHB2 SORL1 GALNT10 MICAL2 SEMA3C CCNG2 IFIH1 TSPAN13 MLPH CREB3L1 TFRC SCNN1A SOX9 NDRG1 EFNA1 SLC46A3 MYO1B POSTN CXADR ERMP1 EPB41L4B	0.00135127	UP
JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN	FOS FOSB EGR1 CTGF ATF3 TIMP3 ID4 NR4A1 EGR2 FLNA ITPR1 DUSP1 KLF2 NRP1 TGM2 BCL6 TIAM1 ZFP36 BTG2 TGFB3 CTSH KLF10 STAT5A SGK1 PLK2 ARHGEF1 FZD8 PKP1 RARA FBP2 ZNF239 POLR2A CYP2F1 ID2 BMP4 TSC22D1 MYH9 KRT14 CIAO1 KITLG ITGB5 THBS1 ID1 ACTN4 AMD1 SAT1 PRKCZ NNT PC ATP1A1 CHKA F3 VAMP8 CTNND1 JUP NUMB EPCAM GRB7 SERPINB5 IRF6 CDH1 PADI2 CA2 HMMR HMGA2	0.00135512	UP
RASHI_RESPONSE_TO_IONIZING_RADIATION_1	FOS EGR1 ATF3 DUSP1 DFNA5 G0S2 COL15A1 JUN ZFP36 ADRB2 IER3 HSD11B1 IER2 ZAP70 SGK1 WNT4 CDK4 PAFAH1B2 UTF1 WDR74 S100A1 CCT3 NEDD8 SLBP FAM46A GADD45A VEGFA SDF2 SERPINB6 SLC2A1 REG1B DNAJC17 WWP2 PLXNA2 SEC23A TIMM8A	0.00135559	UP
AMIT_EGF_RESPONSE_40_MCF10A	CYR61 FOS EGR1 EGR3 JUN ZFP36 DUSP5 LRRFIP1 KLF6 UNC93B1 TIMM44 MIS18BP1 BUB1 GNS THBS1 ADM NDUFB6 HSDL2 TUFT1	0.00137077	UP
HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP	EGR1 PTGS2 VNN1 ATF3 EGR2 RHOB HBEGF PPP1R15A G0S2 MS4A4A EREG PFKFB3 CXCL2 BTG2 FAM49A MCTP1 KYNU BST2 GLIPR1 IER3 CCL4 CEBPD CXCL1 HLA-DRB4 TRIB1 SLC16A6 GM2A RIPK2 IL1B PRKAR1A GLUL KLF6 NLRP3 PLAUR KIR3DS1 RPS11 CXCL3 NUP214 ENC1 LILRA5 MANBA HIST2H2BE ZNF185 ETS2 ACTR2 GLRX ADM MAPK14 TMEM127 SOD2 KLF4 ARPC1A CDKN1A FUCA1 RAB20 FBN2 CHPT1 NEU1 SULT1A2 PADI2 WIPI1 ABHD5	0.00137889	UP
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP	CYR61 PTGS2 THBS2 TIMP3 EPHA3 CXCR4 TIE1 CCL11 CXCL12 VEGFC ANGPTL2 FZD7 SPP1 ANGPT1 HEG1 NRP1 MMP9 TGFB1 EPHA7 COL15A1 S1PR1 SERPINF1 FGFR1 FZD4 SPARC PECAM1 CXCL2 TNFAIP2 IGF1 RAMP3 PLXDC1 COL4A2 OSMR TNFSF12 TIMP1 TGFB3 LAMA5 TEK ENG COL18A1 PDGFB EGFL7 IL6 NOTCH4 JAG2 SFRP4 SYN1 WNT5B PTN FLT4 MMP2 PTGS1 NRP2 SH2D2A FGF1 STAB1 EPHA4 WNT2B FZD9 MMP19 NPR1 IL6ST TNNT1 SPHK1 HGF STAB2 ROBO4 EPHB1 TIMP2 PLAU IL1B NOTCH2 WNT10B NOS3 CCR5 WNT1 CALCRL PGF TNNI3 ANGPT2 KDR FLT1 BTG1 IL10 IL12A PLAUR WNT2 CXCL9 DLL3 TGFBR1 EFNA2 KRT1 TMPRSS6 FRS2 IFNB1 CXCL3 F2RL3 ITGB3 CCL5 HIF1A HEY1 CXCL10 PRL EFNB1 EPHB3 GRB2 CXCL5 IFNA1 ANGPT4 JAG1 PDGFRA DLK1 SERPINC1 ITGAV COL4A3 PDGFA CALR CXCR1 VEGFA PLAT EFNA3 PTEN FRZB PF4 F2R FZD6 TNF EPHA1 ADM NAA15 CXCL11 CAST CXCL6 FGFR3 EFNB2 WNT5A PDGFD ERBB2 TNMD FGFR2 F3 ERAP1 EFNA1 AGGF1 GRB7 HMOX1 SERPINB5 MMP1 HPSE IL18 ANPEP PROM1	0.00138056	UP
PID_INTEGRIN3_PATHWAY	CYR61 TNC FN1 SPP1 LAMA4 FBN1 LAMC1 COL4A1 COL1A1 THY1 COL1A2 PECAM1 PDGFRB PDGFB TGFBR2 TGFBI L1CAM FGB SPHK1 EDIL3 PLAU ITGA2B IBSP KDR PLAUR COL4A4 FGA HMGB1 ITGB3 LAMB1 PVR COL4A5 CD47 VTN FGG ITGAV COL4A3 VEGFA COL4A6 THBS1 SDC4 F11R SDC1	0.00139417	UP
LEE_EARLY_T_LYMPHOCYTE_UP	PBK GGH ASPM E2F8 CEP70 KIF15 HMMR PRC1 MYB CENPA TTK NEK2 KIF11 CEP55 AURKA MELK HMGB3 CCNB1 DLGAP5 OIP5 GINS1 GALNT7 TOP2A DTL KIF20A RAD51AP1 CCNB2 TFDP2 MKI67 CKS2 TNFRSF21 NDC80 BUB1B KIF18B CDKN3 NUSAP1 KIF2C LETM1 RCAN1 KIAA0101 MCM4 NEIL3 MCM2 CDK1 TYMS WHSC1 KIF14 NCAPG BIRC5 UBE2C PTTG1 RAPGEF5 SYK BUB1 E2F2 FANCI RRM2 CDCA3 FAIM ATAD2 TUBB4B MCM10 DIAPH3 DNTT GFI1 DSCC1 MPP1 RAG1 SLC1A4 TSHR PON1 CD99 CD1A CD1E CD1B CDC25A PRR11 MZB1 ARPP21 GNA15 TUBB TMSB15A ADA RUFY3 CPVL PALLD NLGN4X AEBP1 SCRN1	0.00143881	DOWN
LIU_SMARCA4_TARGETS	PLN ZFPM2 CRYAB TAGLN MFAP5 CCL2 TAGLN3 PEA15 PODXL SPARC EHBP1 IGF1 ATP8A2 BST2 GDF15 CD53 IFITM2 PARVA BCAM MMP2 ANGPTL4 PIPOX TAL1 COL3A1 S100A13 SH3PXD2A AHNAK NUPR1 ECM1 NOS1 IFITM1 CRYAA LRRC61 SPRY4 SLC15A2 DHRS3 IL32 CA10 ID3 ITPR3 LGALS3BP ARFGEF2 LGALS9 CAMK2N1 IFI27 UPP1 GPRC5A	0.00146335	UP
DALESSIO_TSA_RESPONSE	FOS ATF3 CLU HSPB8 ANXA1 PPP1R15A LGALS1 MAFF SNAI1 ARC GAGE6 SPANXC SPANXA1 DHRS2 GAGE7 NTS CGA GAGE2C GADD45B MMP12 GAGE12I HSPA1A TEX14 SSX1 HIST2H2AA3 FOSL2 STXBP6 HIST1H2BG	0.00146477	UP
LA_MEN1_TARGETS	CNN1 FGF13 BEX1 IGFBP5 DDR2 PRKCDBP ITGA5 ADAM19 SORBS1 SNX10 CRABP1 RGS16 NUPR1 HOXB8 ANP32A AZI2 CASP8 F3 HSD17B11 TSPAN7 PTER	0.00147105	UP
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1	EGR1 GAL CTGF REEP1 GEM EGR3 MAP1B HBEGF BHLHE40 ELK3 EREG MAFF PLK3 EPHA2 DUSP6 TRIB1 DUSP4 DUSP5 AREG RUNX2 NAV2 PHLDA1 FOSL1 KRT81 LPAR6 SLC7A11 LIF MAP3K5 STRN3 STAMBPL1 SPRY4 TNFRSF21 MXD1 MALL ITGA2 MPZL2 PLEK2	0.0014724	UP
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN	PTGIS CCL2 CCL21 PPP1R3C PDE4B CXCL12 G0S2 HBB RRAD NRP1 HEY2 JAM2 KCNJ8 ZDHHC11 S100A8 GIMAP4 B3GALT2 PDE4D B3GALNT1 GJA1 TGFBI C6 ATP1A3 IFIT1 TM4SF1 APLNR CACNB2 PLAU CD14 NKX2-5 F5 GPR22 PTGER4 CTSB LEPROTL1 MARCKS PFKFB2 CRYM TNFSF10 CLCN3 IDH1	0.00147921	UP
BURTON_ADIPOGENESIS_1	CTGF NR4A2 THBD RHOB MAFF PER1 ARL4C DUSP2 IER3 IL6 DNAJB4 CEBPD CEBPB MYC SGK1 PHLDA1 BAG3 FOXC2 RPS25 DLX2 UNC45A WEE1 IRS2 ID2 TSC22D1 ETS2 VEGFA ID3 FOSL2 LITAF NFIL3	0.00148804	UP
KUNINGER_IGF1_VS_PDGFB_TARGETS_UP	TPM2 SDPR SMPX IGF2 NCAM1 DCLK1 DAAM2 LDB3 ATP2B4 PYGM SMTN HSPB2 SGCA CNR1 ACTC1 ITGB1BP2 FBXO17 ENAH GATM PKIA FMO1 IFFO1 MYOG PRKAA2 SGCG TNNT2 TNNT1 ACTA1 TPM1 CKM ACTN3 FST MYH3 TNNT3 COX6A2 PGAM2 MYBPH MYL4 MYLPF MYL1 NEIL1 RYR1 PPFIA4 ATP2A1 TTN TNNC1 SYNPO2L CCDC134 RB1 MYOM2 HDAC11 TNNI1 TNNC2 FAM8A1 BRWD1 PARM1 USP2 FZD5 ERBB3 DDC	0.00151311	UP
REACTOME_CHOLESTEROL_BIOSYNTHESIS	HMGCR CYP51A1 DHCR24 HMGCS1 EBP MSMO1 IDI1 LSS FDFT1 FDPS NSDHL DHCR7 LBR PMVK TM7SF2 GGPS1 SQLE MVD MVK HSD17B7 IDI2	0.00153927	DOWN
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP	CYR61 FOS EGR1 CTGF TPM2 INA FAM107A CDH5 CLEC3B KLF2 ITPKB MAL ITGA5 BLVRA PKD2 DCN TGFB1 GYPC WFS1 PLLP LAPTM5 CX3CL1 ABCA8 RAMP3 VWF ALCAM CLDN5 EGFL7 CTSF A2M RARRES2 HIF3A CYBRD1 MMP23B MSLN IGFBP4 PNRC1 TRIM8 ACTA1 RABGAP1 FHOD1 S100A9 MAPK8IP1 SEPT7 APOC4 TM4SF1 SPIB CPA3 ILF3 CAPN3 SNRNP70 MBD3 ALPL RPL4 HEYL RPL14 GPX4 TBCB H3F3B SRSF6 HAX1 FARP1 TRIOBP NPC2 CDC42EP2 ISCU ATP4B RPS15 RPL13 RPS15A THOC5 SAR1A IL1R1 CSK SGTA RPS23 MAT2A FAM50A EIF1 RPLP1 RPL22 SSRP1 HNRNPUL1 EIF4A1 RPL23A TRA2B PNMT CALM1 FEZ2 COPB1 TLE2 HNRNPA0 OGDH KRT7 PTBP1 CLCC1 FASN TMSB10 MRPL4 MTCH1 EPRS EIF3K APOF SERF2 EDF1 SERBP1 HLA-E NUP43 ARCN1 GGTLC1 NCKAP1 ATP5L SMG7 MAPKAPK3 OXA1L G3BP1 BCAP31 INPP1 COX6B1 RARS DDX52 PGM3 RABGGTB PTP4A1 PGLS CDKN1A WWP2 ATP5B B4GALT5 ATP5D SNX4 SLPI GCC2 TNFSF10 CCDC47 VAMP8 PGD LPCAT3 GPRC5A TFF3 SDC1	0.0015517	UP
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN	REEP1 GREM2 CCL2 OLFML3 RGS2 EDNRA ITPR1 NEFM TRIB2 MOXD1 ATP2B4 KCNH2 ARHGAP15 SPOCK2 SPARCL1 ACTC1 KCTD12 ARHGEF6 PKIA PDP1 TCF4 DDIT4 CCL4 PDE4D SOX11 DUSP4 BBX MSTN LRRN3 MYOG IGFBP3 PHLDA1 PLK2 ZFP36L2 TBC1D8 ADORA1 MYLPF MYL1 FKBP10 SRSF6 COL11A1 PPFIA4 ATP2A1 LARP1 TTN CXorf57 WDR7 NEB TRIL SPRY4 YY1 TNNC2 LRP5 GLRX GAS2 MICAL2 MARCKS FGF9 PPP1R3D MAP3K9 COBL C3orf52 PLCB4 TNIK EDN3 EXPH5	0.00155958	UP
REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE	LCK HLA-DQA1 HLA-DPA1 HLA-DRB5 CD4 HLA-DRB1 CD3D CD3E HLA-DPB1 CD247 ZAP70 CD3G	0.00162967	UP
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN	CTGF TIMP3 SFRP1 CCL2 RHOB CFH EPHA3 NOTCH3 TIE1 CDH5 RAMP1 GRB14 DIXDC1 FZD7 ANGPT1 TGFB1 HEY2 EPHA7 EREG HSPB2 FGFR1 FZD2 HAND2 CXCL2 VEGFB FGF2 IGF1 PLXDC1 PDGFRB LAMA5 RAMP2 EPHB6 EPHA2 WNT5B CXCL1 PTN FLT4 FZD10 LPXN MMP2 PTGS1 DVL3 PDGFC ANGPTL4 FZD3 NRP2 LEP SFRP5 STAB1 EPHA4 WNT2B TNFRSF12A MMP19 NPR1 FRS3 EPHB4 HGF STAB2 CSF3 CXCR2 OSM NOTCH1 FGF6 WNT7B NOTCH2 TGFB2 EPHA5 FZD8 TYMP LECT1 BTG1 HEYL KLK3 FZD1 MDK CD36 CHGA PHEX DLL3 DVL2 WNT7A TMPRSS6 FRS2 EFNA5 F2 DVL1 ITGB3 ANGPTL3 F7 EPHB3 NPPB CXCL5 EPAS1 PDGFRA COL4A3 CALR PRSS23 IFNG PLG VEGFA PTEN FRZB THBS1 ID1 EPHA1 EPHB2 NAA15 ANG ID3 TNFSF15 EGF SLC19A1 FGFR3 FGFR4 ERBB2 FGFR2 NUDT6 AGGF1 SERPINB5 CEACAM1 F2RL1 FZD5 ANPEP TGFA	0.00163188	UP
KAYO_CALORIE_RESTRICTION_MUSCLE_UP	GAS1 DES CALB2 MYH10 FLNA FN1 NR4A3 CLEC3B TUBA1A RASSF2 EMP3 S100A4 BCL6 COL6A3 COL1A1 COL1A2 HCLS1 MAPT LAMA2 LUM CD302 ENG FAP IER2 HSPA6 C1QB VAT1 HSPG2 TGFBR2 RBP1 ATP2B2 IGFBP4 SNTA1 SOX15 COL3A1 CCNI GDI1 KLRK1 CPA3 PLAU CCR5 CYB5R3 LIMK1 RGS6 ZKSCAN3 PHKG1 S100A11 CALB1 SPTAN1 GNL1 ELANE LRP1 KL SAFB PSG1 NAGLU ITGB8 CHKB ACTB DRD2 DHX38 ZNF211 PDK4 ALB TANK SRY MYH9 RASA2 CNN3 PAFAH1B3 AP2S1 RNF113A KLHDC3 FGL1 RYK CUX1 ACTR1B SLC2A4 ARCN1 CKAP4 TCF12 APP STX4 SCRIB DEFA6 FAS TOB1 FABP5 MTMR11 CCL13 UPP1 GJB1 SLC1A1 KRT12	0.00163219	UP
PID_ILK_PATHWAY	MYL9 TNS1 ZEB1 LIMS2 JUN ACTN1 ARHGEF6 PARVB ZYX GIT2 PARVA CCND1 SNAI1 ILK PARP1 LIMS1 PPP1R12A TACC3 ELMO2 RHOG RUVBL1 AKT1 XPO1 NACA ILKAP HSP90AA1 PPP1R14B CTNNB1 NCK2 ARHGEF7 CKAP5 DIAPH1 CDC37 CREB1 RUVBL2 PXN IQGAP1 RAC1 CDC42 GSK3B AURKA	0.00164	UP
KEGG_ECM_RECEPTOR_INTERACTION	THBS2 TNC ITGA7 THBS4 SDC2 FN1 SPP1 ITGA5 TNXB LAMB2 COL5A2 SV2B LAMA4 ITGA1 LAMC1 COL6A3 RELN COL4A1 COL1A1 SDC3 COL6A2 COL1A2 LAMA2 VWF COL4A2 COL6A1 LAMA5 ITGA4 SV2A CD44 COL5A1 HSPG2 GP1BB THBS3 ITGA9 LAMA1 GP1BA COL3A1 LAMB4 ITGB7 COL5A3 ITGA2B COMP IBSP AGRN COL11A2 COL2A1 GP9 TNN SV2C CD36 COL4A4 TNR ITGA8 COL11A1 ITGA10 ITGB8 ITGB1 ITGB3 LAMB1 GP6 CD47 DAG1 GP5 VTN ITGA3 LAMC3 ITGAV ITGB5 COL4A6 THBS1 SDC4 ITGB4 CHAD ITGA6 LAMC2 ITGA2 LAMA3 LAMB3 HMMR SDC1 ITGB6	0.00169216	UP
KUNINGER_IGF1_VS_PDGFB_TARGETS_DN	MGP GREM1 THBS2 THBD IL33 CAV2 RBPMS ARHGAP6 LBH RCAN2 PLXDC1 TIMP1 CD53 STOM DUSP6 DUSP4 PTGS1 MMD ATP1A3 GFOD1 SPRR1A C14orf79 PHEX BHMT IL1R1 ADO SPAG5 F2R CAPG TPX2 F3 EPS8 PRKG2 CRYL1 HMGA2	0.00169432	UP
NUTT_GBM_VS_AO_GLIOMA_UP	IGFBP5 GAP43 AP1S2 FLNA LAMB2 MAOB MSN VIM LAPTM5 CLIC4 CHL1 TMEM109 FADS3 CD74 PLEKHM2 FZR1 MAPK4 BTN3A2 SMOX PIK3R2 DCTD AQP4 TP53BP2 CAPZB RBBP4 LRRC41 STAT1 TMED9 DYNLT3 TAGLN2 NUCB1 GALNT2 HIPK1 LHFPL2 CAP1 HLA-F CLIC1 LDHA ITGB4 DDOST CAPNS1 GPI TMX1 SH3GLB1 AGL	0.00175891	UP
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN	TPM2 MLLT11 DMD SFRP1 MYH10 PTRF FBLN1 SCHIP1 CAV1 HTRA1 C1orf216 RAMP1 KANK2 CALD1 DPYSL2 TCEAL1 PLS3 SPARC ALCAM ARHGDIB MAMLD1 PTMS TCF4 ARHGEF17 NR2F2 NFIC KIAA0930 NAV2 TGFB2 ATP10D CCND3 PDLIM4 NPM1 DSTN DST SPRY2 HARS GBP1 RGS20 SRSF6 CRIM1 GAS2L1 HMGN3 S100A1 ASF1A SRRT PTDSS1 IFIT5 TTC3 RAP2A DKK1 SYNCRIP SLCO2A1 CHD9 GCAT ISOC2 BCLAF1 DLG5 TSPAN14 PARN PCMT1 SRSF2 ZMIZ1 WDR73 COL4A6 HEXIM1 MRPL20 DROSHA DDX46 TNS3 STARD7 THBS1 DENR NCAPG BAG1 DPM3 LASP1 KIAA0100 PTPRK RUSC1 UBP1 ATP1B3 PRKACB RACGAP1 DCAF6 COMMD8 ADI1 TOB1 CENPF SPATS2L AIM1 EPS8 ZWINT GALNT7 KIF4A NQO1	0.00177626	UP
CORRE_MULTIPLE_MYELOMA_DN	FOS GAS1 CH25H OLFML3 FBLN1 MEOX2 CXCL12 BLVRA NLGN4X SETBP1 COLEC12 PENK LAPTM5 NPR3 LAMA2 IGF1 PLCL1 RBP4 SLC1A3 CEBPD LPAR1 GYG2 MME BARD1 MAF RPL39L ACAN ZFP36L2 PRKRIP1 FZD1 WISP1 INSIG1 TGFBR1 COL11A1 LIN7A HS3ST3B1 CADPS2 EZR EYA2 HOXA10 ALDH7A1 SELENBP1 NEK2 HOXA9 IMPA2	0.00180891	UP
BIOCARTA_THELPER_PATHWAY	THY1 ITGB2 PTPRC ITGAL CD2 ICAM1 CD4 CD3D CD3E CD247 CD28 CD3G	0.00184637	UP
SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN	SFRP1 ELAVL4 MEIS1 SLIT2 FBLN5 RASSF2 OLFM1 TIAM1 BASP1 IGF1 TCF4 CRMP1 NUDT3 INHBA TRIM8 ETS1 RBFOX2 DDX6 NASP STMN1 CDK2 HMGB1 ELAVL1 SMARCA5 CDC27 PUM1 SPTBN1 NFIX RRM2 EIF3A YWHAZ COLEC10 ANKRD11 SOX4 HOXA10 KLF3	0.00196515	UP
AMIT_EGF_RESPONSE_60_HELA	CYR61 FOSB CTGF NR4A2 RHOB NR4A3 BHLHE40 PER1 TNFAIP2 RUNX3 FOXC1 SLC2A3 CCND1 ZFP36L1 SERPINE1 FXR1 KLF10 LDLR SNAI2 NKTR MOAP1 DNAJC24 PTPN11 KLF6 MBNL2 LIF PMAIP1 TIPARP UGCG HSPH1 DCUN1D4 H3F3A NCKAP1 CITED2 VEGFA NAA15 EXOC5 FOSL2 HES1 SOD2 PLSCR1 MED20 ATG4A SLC20A1	0.00197611	UP
MOOTHA_TCA	SUCLA2 IDH3A SDHB SDHC SDHD MDH2 SUCLG1 ACO2 SDHA FH IDH3B IDH3G CS IDH2 OGDH RPL18A	0.00198549	DOWN
LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP	CYR61 PTGS2 CTGF DUSP1 FBLN2 SPP1 ANXA6 PYGM BHLHE40 ELK3 SEPT6 NRP1 FXYD5 ROBO1 HTR2B CPE NME4 CORO1A FZD2 JUNB CACNA1H CD81 POU2AF1 DBN1 BACE1 PDGFB ZYX CDH2 SOX11 DOK2 GPC1 MAP2 MSLN SERPINE1 GSN INHBA RUNX2 LPIN1 CD70 SGK1 FAM50B CHST6 AHR CKM FOXH1 PLA2G4A RGS6 SEPT9 CLCN4 IL11 NCOA1 OPRK1 BPGM MMP14 FURIN ATXN10 WISP1 ACOT9 NEU3 BFSP1 RPA2 ALOXE3 ITGB1 ACTB RASAL1 RAG2 ANAPC1 AQP4 SMARCAL1 ELOVL2 IL15RA POLR2B MOGS SYNGR4 CCL7 JAG1 MAGED1 BMP1 TMSB4X LEPROT MYH1 AK1 OR7C1 ANKRD1 GADD45G B4GALT1 TAT EFNA3 SLC15A2 GAD2 ASS1 RCN2 CAPG TSPAN3 WNT5A FGFR4 AKAP7 ATP13A3 HN1 KRT8 TSPAN7 LAMB3 ITGB6 TMOD3	0.00200779	UP
VALK_AML_CLUSTER_11	SERPINB9 DPYSL2 DNM1 FYN EVL CD200 SPARC KYNU CLIC4 GIMAP6 ST3GAL5 DAPK1 EGFL7 GIMAP5 CD34 DAB2 DUSP7 MDFIC PALM CIITA KLF9 LPAR6 REEP5 GAS2L1 IFITM1 KCNN4 CISH LHFPL2 VEGFA SLC38A1 APP H1F0 ASS1 ALDH2 ITGA6 MYO5C	0.00201225	UP
BIOCARTA_TCR_PATHWAY	FOS JUN FYN LCK NFATC1 PRKCB NFATC4 CD3D PTPN7 CD3E PPP3CC PIK3CG VAV1 CD247 ZAP70 LAT PLCG1 PRKCA NFKBIA PPP3CB PIK3CA RELA NFATC3 PIK3R1 MAP3K1 ELK1 HRAS MAPK8 SHC1 CALM1 RAF1 MAP2K1 GRB2 CALM3 CD3G CALM2 PPP3CA RASA1 NFKB1 RAC1 MAPK3 MAP2K4 SOS1	0.00205345	UP
MANALO_HYPOXIA_UP	PTGIS TNS1 NFASC ENO2 C8orf4 FILIP1L APOD MN1 PLEKHO1 CXCR4 AXL SPOCK1 HTRA1 CDKN1C SORBS2 LEPR VEGFC TRIB2 TCF7L1 GPNMB F8 DKK3 DCHS1 RASSF2 KLF11 BHLHE40 BNIP3 BCL6 LIMCH1 GYPC COL4A1 MAFF CHST15 NUAK1 CD200 PDZD2 COL1A2 PAM TMEM45A ARL4C CX3CL1 VWF COL4A2 ITM2A RPS6KA2 LRRC32 BGN DDIT4 COL18A1 PDGFB MAGED2 IER3 ZHX2 NOTCH4 GRK5 DLGAP4 SLC2A3 HIVEP2 KANK3 CELF2 PLCG2 RRAS NFATC4 DUSP6 STC1 CDH2 HIF3A GPC1 COL5A1 MMP2 PTGS1 ANGPTL4 CHSY1 TNFAIP3 SERPINE1 STC2 INHBA TGFBI LIMS1 NPR1 IGFBP3 GDF10 TPM1 PHLDA1 ITPR2 CREB3L2 AFAP1 SEPT4 ALPK3 PLOD1 LOXL2 NENF ZNF292 INHBE COL9A1 MAST4 PGF SLCO5A1 SPAG4 TXNIP ATXN1 SV2C RHOBTB1 NINJ2 ABCA1 GAS6 RGS3 TMCC1 MTHFD2L N4BP3 EPOR MEF2A CHST1 PTPRB GABRP GADD45B ZBTB1 RPL27A MYH13 MZT2B MTSS1 NYNRIN LAMB1 SMAD6 GJA5 BNIP3L SLC6A8 SYNPO KDM3A TLE1 TNFRSF14 ZNF395 SIRT3 NARF FAM46A WASF2 PPP1R13L SHOX2 P4HA1 CUBN HLA-E PXN TRIO FKBP9 TNFRSF10B HLA-B HDLBP B3GALT4 VEGFA RAI14 ATP2C1 RLN1 AK4 IDH2 FNDC3B SPSB1 ADM CDK19 PGM3 INSR HES1 RNASE4 SEC24A PELI2 CCNG2 LOX CLIP2 SOX4 ALDH2 TSKU GLS FAM171A1 EDN1 MXI1 TSGA10 BACE2 TAPBPL NEDD9 DIAPH2 P4HA2 CASK GBE1 VLDLR PTPRF NDRG1 ACVR1B OPN3 NPAS2 PGM1 PLOD2 RBKS EGLN3 MARCH3 ENPP1 CYP4F11 EGLN1 GLCE PPARG PTPRR GRAMD1C	0.00205881	UP
KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	C7 TFPI THBD CR2 CFH SERPING1 CFD F8 C3 F13A1 C1R C1QA C1S VWF C5AR1 PROS1 F10 C5 C1QB A2M C4A SERPINA5 CR1 SERPINE1 C3AR1 FGB C6 C2 PLAU CFI MASP1 SERPINF2 KLKB1 PROC C8B MASP2 F5 F11 C9 PLAUR FGA F13B MBL2 F2 CPB2 F7 BDKRB2 F9 C8A SERPIND1 SERPINC1 FGG BDKRB1 CD59 C8G PLG PLAT CFB KNG1 F2R F12 CD55 C4BPB CD46 F3 SERPINA1 C4BPA	0.0020595	UP
ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION	GEM AKAP12 ATF3 CH25H CCL2 BCL2A1 SELL ADAM19 F13A1 CCL3 ITGAM MAFF PFKFB3 SLC15A3 JUNB EBI3 CXCL2 OAS2 TNFAIP2 CSF2RB OSMR TIMP1 C5AR1 SELP GPR65 IL6 CCL4 CEBPD SAP30 LCP2 LST1 MS4A6A SOCS3 CXCL1 CCR1 SLC26A4 CCR2 PLEK MX2 FGL2 SLA CYBB TNFAIP3 ST3GAL1 CCL20 SERPINE1 PLA2G7 FCER1G CCL17 TFEC TGM1 CSF3R NFKBIA MAP3K8 TFPI2 IFIT1 IL1B ISG15 CD14 TNFSF9 CSF2 FCGR2A CASP4 STAT2 TLR2 MEFV PLAUR TREX1 GBP1 IRF7 VCAN IL1RN ZNF652 CXCL10 MARCKSL1 USP18 BCL3 HPX OAS3 STAT1 RELB CLEC4E NARF IL1A SSBP3 FCGR1A MT2A GADD45G THBS1 BST1 ADM ARG2 IL36G SOD2 CXCL6 IFIH1 RCAN1 IFIT2 IL15 RDH5 RAB20 LITAF GCH1 MXD1 F3 GK NFIL3 UPP1 CCRL2 ATP10B IL1R2	0.00206412	UP
CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN	PBK CMAS ECT2 IMPA2 HIST1H2BH MAD2L1 GNAI1 RFC5 GMNN SNX7 TSPAN6 MRPL13 APOO RAD51AP1 CCNB2 NEU1 PGD SEC23B MRPS12 TPX2 STT3A GLUD2 MRPL42 MCTS1 TM9SF2 SLC25A5 ACTR6 ALG13 ME2 ATP6V0D1 RNF141 DBI KIAA0196 TPRKB UQCRFS1 PRKAB1 YAP1 ATP1A1 C1GALT1C1 CDKN3 UBE2E3 NUDT21 MRPL44 G3BP2 ARPC1A CAB39 CAPZA2 PSMG1 NUP37 TMX1 PSMA5 RNASEH2A WDR61 C1QBP BAX STOML2 MRPL39 COPA MED21 DAD1 S100A10 ALDOA PSMD10 CDK1 PGK1 ATF1 ZNHIT3 PPP2R3C TYMS PSMD8 RCN2 PDIA6 METTL13 PRDX4 POLE3 RPA3 PIGF TMBIM4 DPM1 POLE2 ATIC ABHD6 RAE1 TAB2 NFYC CITED2 ILF2 RFC3 TMEM50A PCNA C1orf112 MSH2 CLNS1A VBP1 SCAMP3 CHCHD2 PSMC3 PSMA2 SNX2 HSPA8 UXT ATG3 DNAJB9 SEC11A SEC61A1 RHOA SNRPD1 VAMP3 DNAJA1 MAGED1 CNN3 ADH5 HAT1 NUP205 VDAC3 SYPL1 HNRNPA0 FARSA CCT2 COPS3 FEN1 H2AFZ FKBP11 XRCC5 YBX1 CCT4 DCTN3 MAPRE1 RPL7A NDUFA4 RPS16 HSP90AB1 MANF RAN NONO LYZ LSM2 E2F5 CDK4 HSPA13 STIP1 SNRPD2 GTF2I WARS RFC4 FCER1G SLC39A6 GJA1 PRPS1 CTNNAL1 TPD52L1 TYROBP SLC29A1 BAG2	0.0021673	DOWN
BIOCARTA_LYM_PATHWAY	SELL VCAM1 PECAM1 ITGB2 ITGA4 ITGAL ICAM1 CD34 ITGB1 IL1A	0.0022021	UP
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN	FOS GAS1 CTGF AKAP12 MFAP5 ATF3 TIMP3 NDRG4 FHL1 PMP22 DUSP1 KLF2 LPL TCF7L1 PLTP TNXB LAMB2 FSTL1 AMOTL2 COL5A2 ELN FBN1 TUBB2A COL1A1 PCOLCE FZD2 COPZ2 COL1A2 PER1 TMEM45A TSPAN4 SLC29A1 COL4A2 SNX10 AQP1 GRB10 ST3GAL5 CRTAP GRK5 SAMHD1 SOCS3 PSTPIP1 RECK COL5A1 MSLN VAMP5 CRLF1 ENO3 GSN SLCO3A1 IL6ST SLC4A3 S100A13 NOTCH1 CDKL2 SEC14L1 ISG15 ATP11A NUPR1 STK10 IFI30 SPTAN1 NMT1 FKBP10 INSIG1 BMP8A MAN2B1 COL11A1 ARL2BP PEF1 PFKP KAZALD1 SMAD6 RAB11FIP5 INPP5A COL4A5 RNPEPL1 HOXA2 SPTBN1 SLC1A5 SESN1 CD151 GSTM1 ASAH1 MAP1LC3B RBMS2 SEC61B PRSS23 GUK1 ITGB5 EPHX1 ABLIM1 CITED2 ALDH1A1 DHRS3 APP IFI35 CTDSP2 ADM LASP1 CHFR ID3 RNASE4 SEMA3C EMP2 TMEM159 DGCR2 DHRS7 WWP2 COQ9 CD9 TOB1 DDR1 SLPI CCDC6 LGALS9 PNP JUP PLAC8 SRI PAPSS2 LLGL2 VDR PHYH CALML4 HIST1H2BC SLC38A4	0.00220733	UP
GAURNIER_PSMD4_TARGETS	CCL2 CXCL13 CCL19 CCR7 C3 TGFB1 CCL3 IL21R IL16 CXCL2 CCL18 HLA-DQB1 HLA-DQA1 C5AR1 HLA-DRA CCR10 HLA-DPA1 HLA-DMA HLA-DRB5 CD86 IL6 HLA-DRB1 CXCL1 CCR1 HLA-DRB4 HLA-DMB HLA-DPB1 CCL20 C3AR1 HLA-DQB2 IL18R1 C2 CCR5 IL2RG NFKB2 IL10 CXCL9 HLA-DOA TGFBR1 CCL23 IL12B CXCL3 CCL5 IL12RB1 CCL1 CXCL10 CCR3 IFNGR1 CCL8 IL17RA CCL7 RELB B2M IL1A HLA-E HLA-C HLA-G HLA-B NFKB1 HLA-A HLA-F TNF CXCL11 CXCL6 IL13RA1 IL22RA1 CCL13 IL1R2 IL7	0.00224562	UP
AMUNDSON_GAMMA_RADIATION_RESPONSE	MAD2L1 PRC1 CENPA TTK NEK2 CCNA2 CDC25C AURKA CCNB1 CCNB2 CKS2 AIMP2 BUB1B CENPF CENPE KIF23 KIF2C ESPL1 CDK1 PPP2R5A UBE2C AURKB PTTG1 TSN H2AFX DNMT3B BUB1 PRRG2 LBR PLK1 GTPBP1 WEE1 RRP1 MSX1 CCNF KIFC1 TACC3 CDC25B CDKN2C	0.00234377	DOWN
KONG_E2F3_TARGETS	PBK HMMR PRC1 MYB KIF11 CCNA2 AURKA MELK CCNB1 DLGAP5 TOP2A KIF20A CDC20 RAD51AP1 MKI67 TPX2 RBBP8 SPC25 CDC6 EZH2 BUB1B CENPF SKP2 CDC7 SMC2 DEPDC1 LMNB1 RAD51 NUSAP1 KIF2C RACGAP1 NCAPD2 ASF1B KIAA0101 HIST1H4B BRCA1 TYMS TK1 NCAPG NCAPG2 NCAPH HIST1H2AD NUP50 UBE2C HIST1H4F H2AFX PSORS1C2 BUB1 CDCA3 E2F3 HMGB2 PLK1 DNA2 ERCC6L FEN1 USP1 SRSF7 CHAF1B MAPK8 PRIM1 CENPQ HIST1H4I INCENP RPL3 RAD54L TAF1D RPL12 NR1D1 FAM111A NASP CCNE1 DCK CCNF MCM3 MED1 RBL1 CBX2 TACC3 GP1BA SHCBP1 PSIP1 HLX F13A1	0.00236113	DOWN
INAMURA_LUNG_CANCER_SCC_DN	ADAMTSL3 CAV1 RASL12 AKAP2 ADARB1 ABCA8 VWF ADAMTS8 PGM5 ST6GALNAC5 NR2F1 AGER PHACTR2	0.00241105	UP
NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP	CTGF SRPX THBS2 CCL2 COL6A3 TIMP1 LRRC32 SFRP4 CXCL1 MME GNA15 PLAU LIF CCL7 SH3BGRL3 BST1 RAB21 LOX	0.00242191	UP
TRAYNOR_RETT_SYNDROM_UP	AKAP12 PTGER3 FBLN1 CALD1 MOXD1 PLCB1 C1R PENK TCF21 PRUNE2 SPON2 IFI44 IL6 SLC16A7 RPS6KC1 SVIL LTBP1 PLA2G4A SNTB1 MMP3 MMP10 STAT1 GAPDH BID DPP4 DNASE1L1 CA12 HSPB3 MMP1 SYTL2	0.00242938	UP
PID_INTEGRIN2_PATHWAY	CYR61 C3 JAM3 VCAM1 ITGAM THY1 SPON2 ITGB2 ICAM2 F10 ITGAL ICAM1 ICAM4 TGFBI GP1BA FGB ITGAX CD40LG PLAU PROC FCGR2A PLAUR FGA ICAM3 FGG PLAT KNG1 F11R	0.00243287	UP
BIOCARTA_BLYMPHOCYTE_PATHWAY	CR2 FCGR2B ITGB2 PTPRC HLA-DRA ITGAL ICAM1 HLA-DRB1 CD40 CR1 CD80	0.00249553	UP
NABA_PROTEOGLYCANS	OGN ASPN SPOCK1 PRELP DCN OMD SPOCK2 LUM BGN SRGN HSPG2 FMOD ACAN IMPG2 HAPLN2 PRG2 PODNL1 SPOCK3 ESM1 PRG3 BCAN IMPG1 VCAN NYX KERA PRG4 NCAN EPYC CHAD HAPLN1	0.00251763	UP
SIMBULAN_PARP1_TARGETS_UP	MGP MFAP5 TIMP3 CAV1 FGF7 IGFBP6 GPX3 ELN DCN CD81 SERPINE2 CCND1 NOV IGFBP4 CCND2 PRRX2 TIMP2 FST EEF2 MDM2 COL4A5 TINAGL1 COL8A1 AK1 APP ID1 S100A6 CCNG1 CTTN CDKN1A ANXA3	0.00255842	UP
CUI_TCF21_TARGETS_UP	CFH NCAM1 ISLR CADM1 DCN PENK SERPINF1 PHGDH COL6A2 CDH6 LUM COL6A1 FAP COL8A2 PTN SOX11 RBP1 LBP EPHA4 COL3A1 CCND2 HOMER2 CLDN9 CLDN6 CYP7B1 MDK VCAN EMID1 HDAC11 CDKN1B HJURP LHFPL2 IGFBP2 HMMR	0.00260824	UP
ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN	FOS EGR1 AHNAK2 SRPX AKAP12 IGFBP5 ENO2 PTRF CXCR4 CAV1 LOXL1 SPOCK1 ITPR1 VEGFC CSRP2 SAMD4A OBSL1 BHLHE40 BNIP3 S100A4 LIMCH1 DPYSL2 SFXN3 PFKFB3 FYN PAM TMEM45A WISP2 PDGFB SH2B2 HLA-DRB1 STC1 ANGPTL4 GJA1 SERPINE1 IGFBP3 RBPJ NOL3 SH3GL3 ALDOC RASA4 LOXL2 ZNF292 YEATS2 UPK1A EIF5A SPAG4 RRAGD ATXN1 DPYSL4 PLAUR KRT15 DST PPFIA4 WSB1 GYS1 ANKZF1 HEY1 KDM4B CA9 SCNN1B BNIP3L QSOX1 ZNF395 P4HA1 CITED2 SRD5A3 INSIG2 VEGFA EFNA3 AK4 PDK1 GLRX ADM ANG PGK1 RNASE4 CYB5A EGFR SLC2A1 CCNG2 LOX ILVBL MXI1 PGAP1 FAM162A FAM13A P4HA2 GBE1 SOX9 VLDLR PLIN2 NDRG1 STBD1 PLAC8 PGM1 ZNF654 HK2 EGLN3 GPRC5A EGLN1 DSC2	0.00263891	UP
LUCAS_HNF4A_TARGETS_UP	DNAJC22 DSC2 PKP2 ETFDH VIL1 ACOX1 SMAGP MTM1 ERBB3 ATP7B KIFAP3 CALML4 RBKS ACOT13 SELENBP1 ACY1 DERA COBL SLC35D1 ABCB1 EBP SLC25A20 C1orf115 KIF13B ALDH5A1 MGST2 TACC2 DHRS1 IL13RA1 CAMKK2 DDAH2 SLCO4C1 MAN1A1 TECR AKAP1 BIRC2 LASP1 TRAF4 SDC4 CIDEB ACADVL ATXN7L1 CFLAR OSBPL3 HNF4A PRKCSH MPP1 WT1 PKIG IL18R1 ABCB4 EFHD1 COL21A1 NID1 PRPH	0.00274481	DOWN
KANG_GIST_WITH_PDGFRA_UP	REEP1 HSPB7 TNC ITPKB ANGPTL2 DKK3 PRELP RAB31 SPOCK2 RELN CPE CHRNA3 THY1 IFI16 C1S LCP1 GIMAP6 GLIPR1 LCP2 IGFBP4 TGFBI ADAMTSL2 FJX1 PDE1B MAPK8IP1 IFIT1 IRF8 MX1 ISG15 CCR5 KDR TDRD12 S100A1 CXCL10 USP18 PDE7B ADAM28 RAB38 PDGFRA CXCL14 SIK2 SPON1 RHOBTB3 PPP2R1B IGFBP2 BMP5 CPM	0.00276714	UP
HOLLEMAN_DAUNORUBICIN_B_ALL_UP	EGR1 THBD PCDH9 CHD4 LARP1 KCNN4 EIF2B4 CDC37 CNTN5 ATP1A1	0.00278654	UP
URS_ADIPOCYTE_DIFFERENTIATION_DN	THBS2 LOXL1 FN1 CD37 SNN PTGDS DCN MMP9 COL6A3 SPARC COL4A2 LUM LRP3 ROM1 TMEM179B COL3A1 OSGIN1 PTPRN MED1 ADORA1 E2F4 NUMA1 PPP2R1A PSG9 LRP5 LOX PPARD CEBPA	0.00278937	UP
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP	MGP THBS2 GREM2 ENO2 CCL2 TNC IGF2 LOXL1 NID1 NCAM1 FGF7 CYP1B1 CDO1 C3 ADAM19 CAPN6 NRP1 LAMA4 VCAM1 EVL THY1 TPST1 IFI16 RAMP3 TWIST1 OSMR ENAH CRABP1 PDPN NAP1L1 IL6 CEBPD LTBP2 CEBPB LSP1 AOX1 LPAR1 ANP32E SLC38A2 NAV2 PHLDA1 APBB1IP CSF1 SRSF3 FAM3C AGTR2 CASP4 CHI3L1 GPC4 PCF11 DPEP1 SRSF6 VCAN TAF1D IL1RL1 NOC4L PSPC1 IL1R1 LAMB1 PFN2 PDK4 SRRT CTSB UTP14A SLC6A8 SYNPO HSP90B1 MAGED1 DLK1 PLA2R1 H2AFX TOP1 BACH1 TMEM176A HAS2 HTATSF1 PTEN MYL12B GTF2A2 THBS1 UBE2D2 F2R PTX3 IVNS1ABP TMEM176B RAB11A CXCL6 LOX PPID PGRMC1 LMO7 PLSCR1 EFNB2 RBM3 IMPACT CASK FGFR2 ATP13A3 CCNB2 PDK3 SEPHS2 SLC12A2 MAN2A1 LXN ANK3 LAMP2 XDH SLC16A1 HMGA2	0.00279222	UP
ZIRN_TRETINOIN_RESPONSE_UP	CTGF AKAP12 CCL2 VGLL3 LAMA4 TAL1 SLC38A2 RARB PLK2 RARG PLAUR RARRES3 NID2 SLCO2A1 GFM1 THSD4 DHRS3 VMP1 IQCK	0.00282952	UP
STEGER_ADIPOGENESIS_DN	OGN THBS2 TIMP3 DPT OLFML3 FSTL1 CAPN6 MAGED2 PDPN CD44 MMP2 RBP1 PLA2G7 RAB3IL1 TIMP2 WISP1 PDLIM2 DLK1 PLAT RNASE4 LOX WNT5A POSTN	0.0028463	UP
BIOCARTA_TCRA_PATHWAY	FYN PTPRC LCK HLA-DRA CD4 HLA-DRB1 CD3D CD3E CD247 ZAP70 CD3G	0.0028539	UP
DEMAGALHAES_AGING_UP	CLU IL33 APOD SERPING1 HBA1 EFEMP1 DCLK1 GPNMB SPP1 C3 S100A4 FCGR2B MSN C1QA LAPTM5 CLIC4 VWF ANXA5 C1QB VAT1 C4A GSTA1 SGK1 ADARB2 RASA3 TXNIP FCGR2A GBP2 LYZ NPC2 B2M GFAP HLA-G GNS TMED10 PTGES3 S100A6 PSMD11 DERL1 MT1F ADIPOR2 LGALS3 LITAF CTSS NDRG1 PCSK6 HIST1H1C ANXA3	0.00286136	UP
KEGG_FOCAL_ADHESION	MYL9 THBS2 TNC CAV2 ITGA7 CAV1 THBS4 FLNA FN1 VEGFC AKT3 SPP1 FLNC ITGA5 TNXB LAMB2 COL5A2 LAMA4 ITGA1 LAMC1 COL6A3 JUN RELN COL4A1 MYLK COL1A1 COL6A2 FYN COL1A2 VEGFB ACTN1 LAMA2 IGF1 VWF COL4A2 TLN1 COL6A1 PDGFRB LAMA5 MAPK10 PIK3CD ITGA4 PDGFB PAK3 PRKCB RAC2 PARVB ZYX PARVA CCND1 FLT4 SHC2 COL5A1 PIK3CG PDGFC VAV1 THBS3 ILK ITGA9 BCL2 PIP5K1C LAMA1 PPP1R12A PIK3R3 COL3A1 HGF LAMB4 CCND2 VCL ITGB7 COL5A3 PRKCA ACTN2 PRKCG PIK3CA MYL7 ITGA2B ACTN3 COMP CCND3 IBSP MYL10 BIRC3 PGF COL11A2 KDR MYL2 AKT2 COL2A1 ROCK1 FLT1 SHC3 TNN AKT1 PIK3R1 MYLPF RAC3 COL4A4 TNR ITGA8 COL11A1 ELK1 RASGRF1 PAK2 ITGA10 PIK3R5 ITGB8 ITGB1 ACTB ITGB3 LAMB1 CAV3 RAPGEF1 RAP1A HRAS PIK3R2 MAPK8 PTK2 VAV2 SHC1 CTNNB1 PDPK1 VASP DIAPH1 VTN RAF1 MAP2K1 BRAF GRB2 RAP1B PAK6 ACTG1 ITGA3 PDGFRA MYL5 LAMC3 RHOA ITGAV PDGFA IGF1R PAK4 PXN ARHGAP35 ITGB5 MYLK3 SRC VEGFA COL4A6 PTEN PPP1CC PPP1CB MYL12B RAC1 THBS1 BAD DOCK1 MYL12A ACTN4 CDC42 ITGB4 MAPK9 MAPK3 CRKL ROCK2 BIRC2 SOS1 PPP1CA CHAD EGF EGFR CRK GSK3B TLN2 SOS2 ARHGAP5 FLNB CAPN2 PDGFD ERBB2 PIK3CB ITGA6 XIAP MET MAPK1 LAMC2 ITGA2 LAMA3 PAK1 LAMB3 VAV3 ITGB6	0.00287145	UP
CHESLER_BRAIN_HIGHEST_EXPRESSION	FOS SYT1 PLP1 ACSL4 KCTD12 CSRP1 A4GALT MOBP ATP11A GRIA2 CADPS MATR3 C9orf16 MARCH7 ACTB DCTN3 RABAC1 PRKCE GNB1 HNRNPA2B1 SCN1A UQCRB STRN3 GLO1 KIF5A PSMB5 ATP6V0B PPP1CB HINT1 SP3 CXorf56 PPID LIN7C ATP13A3	0.00287724	UP
BAELDE_DIABETIC_NEPHROPATHY_UP	PTGIS EML1 IGFBP5 CLU ZCCHC24 RBPMS CCDC69 TIE1 CLEC3B PDE2A HBB CCL3 PECAM1 PTPRM ICAM2 ITM2A PPM1F AQP1 TEK ENG CTSH RAMP2 CD34 NOTCH4 MAP4 VAT1 CCND1 PPP3CC ARHGEF15 MYC STARD8 HYAL2 BBOX1 ADAMTSL2 GDPD5 CRHBP CAPN3 FXYD2 HYAL1 SLC22A6 AANAT GAS6 DPEP1 LYZ SLC6A7 PTPRB GAS2L1 ACVRL1 ALDH4A1 SPG7 GPLD1 SLCO2A1 TLE2 FAM53B INPP5K MT3 FTL UNC5B HPN MT2A ENO1 LTK ID1 ASS1 SEMA6A AKR1A1 MT1G CRIP1 BAX CD24 FBP1 BPHL ACY1 ATP10B IMPA2 CYP4F2 AKR1C3	0.00288214	UP
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_DN	NR4A2 P2RY14 PTGER3 S100B RGS2 SDC2 CYP1B1 HBB CD1C ENTPD1 GNB5 BTG2 ARL4C HLA-DQB1 PLXNC1 LTB GPR171 CCR6 ST8SIA4 FGL2 HDC PDE4A GGA2 HIP1 IRF4 ITGB7 GM2A UTRN CPA3 ADAM8 CD1B SMARCA2 CD1E RNF24 PTPN22 CD1A TMEM206 ICAM3 KAT2B UGCG HNRNPH1 MDM4 SLC38A1 STK17B IVNS1ABP CASP8 ROCK2 ADAMDEC1 CLC MAP3K2 CD46 AP3S2	0.00288347	UP
MARCHINI_TRABECTEDIN_RESISTANCE_DN	DLC1 LOXL1 ACTA2 NID1 NOTCH3 FSTL1 BHLHE40 PRNP IGFBP7 PKN1 SIRPA COL4A2 SLC7A5 BCAM RUSC2 CDH13 CNTN2 IMPDH1 COL3A1 TPM1 ACTN2 SLC3A2 GABRA5 AKT2 CAD MARS MYH8 EIF4A1 SLC1A5 HSP90B1 HSPA5 ACTG1 RND3 PYCR1 CALR CBLB ANKRD1 HLA-B HDLBP CITED2 PLXNB2 PTTG1IP PSMF1 ADM SLC16A3 GPI CSNK2A1 MARCH8	0.00288529	UP
AIGNER_ZEB1_TARGETS	OCLN DSC2 TMEM30B MPZL2 CLDN7 CXADR F11R DSP CDH1 TSPAN1 PKP3 EPCAM SH3YL1 EPPK1 CD24 TSPAN15 SFN MUC1 TACSTD2 SCEL CDH4 GJB3 CDH3 PMEPA1 CDH11 PPL PCDH7	0.00290568	DOWN
LINDSTEDT_DENDRITIC_CELL_MATURATION_D	PTGER3 EGR2 ANXA1 ITGA5 F13A1 RAB31 ITGAM PECAM1 ITGB2 ACTN1 IFI16 ARHGDIB CCL22 CLEC2B NCF2 DMPK HLA-DMA ADCY7 DAB2 LST1 CCR1 CDH2 HLA-DRB4 HLA-DMB FGL2 CLEC10A CIITA TGFBI MAF NPR1 FCER2 TPM1 ITGAX SLC6A2 AQP3 ACP5 DNASE1L3 P2RY6 ALOX15 DNMT1 CD99 MAN2B1 IGSF6 RAP1GAP RCBTB2 LAPTM4A QSOX1 IFNGR1 TPP1 SYPL1 SLC1A5 RBMS2 ITGAV MKNK1 TOP1 MTMR6 NCBP2 CCNH DOCK1 PTPRE NAGA ATP6V1A FCGRT CTNND1 NAAA PRSS3 CDH1	0.00290944	UP
VERRECCHIA_RESPONSE_TO_TGFB1_C2	TIMP3 FN1 COL6A3 COL1A2 ITGB2 PCDHGC3 CDH6 TIMP1 COL6A1 ICAM1 WNT2B COL3A1 CD82 RHOG MMP14 MMP3 LRP1 MMP16 DVL1 SSR1 MARCKSL1 ARHGDIA CYTH2 JUP	0.00295454	UP
HAHTOLA_SEZARY_SYNDROM_DN	ZBTB16 BACH2 NCAM1 GZMK MYBL1 SERPINB9 HOPX SPON2 DUSP2 BST2 CCL4 NELL2 BCL2 APBA2 KLRB1 KIR2DS2 NKG7 KLRF1 IRF8 KIR3DL3 IL2RB MATK KIR3DL1 GNLY CTSW XCL1 TXK CCL5 KIR2DL2 IL18RAP PTCH1 GZMB KLRD1 KDM2A SESN1 DLG5 PRSS23 CD160 TSPAN13 VAV3	0.00304983	UP
MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN	CTGF ACTG2 TAGLN FHOD3 APOD EFEMP1 CALD1 PCSK2 WISP2 L1CAM SPANXA1 SNAI2 AQP3 KRT17 EPAS1 TNS3 NT5E FHL2 FBN2 ITGB6	0.0030561	UP
DELASERNA_MYOD_TARGETS_DN	THBD RBPMS PDE4B CXCL12 SDC2 SLIT2 TCF7L1 CAPN6 SERPINB9 DPYSL2 BASP1 CD34 MMP2 ZCCHC11 ADAMTS2 TGFBI ITPR2 BAIAP2 DDIT3 GBP2 KLF6 FZD1 COL11A1 FNBP4 DDX28 IFITM1 TPR ACTL6B EMILIN2 CD47 SYNPO MRPL33 ZMYND8 ATP6V0C CENPM PTEN POLE2 PLP2 PRDX4 CYB5A POSTN HMGB3	0.00305785	UP
MIKKELSEN_MEF_LCP_WITH_H3K4ME3	OGN ASPN ACTG2 CCL2 NNMT ECM2 ANXA1 FHL1 ANGPTL2 LDB3 EMP3 SERPINB9 EMILIN1 SERPINF1 PCOLCE CP C1orf54 OLFML1 SNX10 ARHGDIB WISP2 LUM COL6A1 PDGFRB DMPK MR1 LSP1 SCN2B INHBA MMP19 GPSM3 COL3A1 HGF MYO7A DAPK3 IFIT1 WARS PKIG BTC IQSEC2 MASP1 P2RX6 ECM1 OSGIN1 SARDH PSPN ARAP1 GAL3ST4 CASP4 TEF TBXA2R TREX1 WISP1 TLR4 CCDC9 GBP1 IL1RN AMPD3 SOAT2 XAF1 IKBKE IL17RC GSTM2 IL18RAP CCL7 ZSCAN2 RNF123 TNFRSF14 ZMYM2 PRRG2 GPR173 TMEM176A SERPINB8 PRICKLE3 IFI35 GLRX ARHGEF11 TRIM21 TMEM176B CAPG ZFAND6 CAB39 RDH5 LGALS3BP TAPBPL DDR1 ELOVL1 LGALS9 ACOT11 VWA5A POSTN XDH CYP2J2	0.0030654	UP
BILANGES_SERUM_SENSITIVE_VIA_TSC1	EGR1 TAC1 GREM2 GRB14 MFAP4 MEOX1 JUNB NNAT KCTD15 DUSP4 PHLDA1 KRT84 SLC22A6 UTP6 TUBA4A DDB1 RND3 TBL2 GNAI1	0.00307028	UP
WANG_LSD1_TARGETS_UP	MGP IGFBP5 CDKN1C CSRP2 RPRM ELK3 LGALS1 RELN TGFB2 CD1D SOX2 SIX1 CCNE1 MDK EPB41L2 GAS6 FOXG1 PDGFA GADD45G EZR HEPH IGFBP2 PYCARD	0.00307614	UP
NAKAJIMA_MAST_CELL	CALB2 CLU ENO2 CCL2 PTRF CYP1B1 CLEC3B TRIB2 GPNMB DUSP14 MAOB RGS10 CTSG CMA1 TSPAN4 TIMP1 GDF15 GATA2 VAT1 HDC LTC4S ENPP2 KIT MS4A2 CPA3 PRG2 FST SIGLEC6 HSP90AB1 FCER1A PEBP1 MT3 GLA PRDX1 PLAT BRCA1 MT1H CAPG LGALS3 PHLDA2 CTSD VWA5A ALAS1 HPGD HPGDS	0.0030937	UP
PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN	HMGCS1 KDELR1 ERAP1 PSMC6 TAPBPL PSMB8 PSMD7 PSMB10 DERL1 TAP2 PSMD11 PSMA3 PDIA3 ERAP2 PSMD8 PDIA6 NGLY1 PSMA6 HLA-A PSMF1 PSMD5 TAP1 PSMA1 PSMA4 HLA-B PSME3 CANX PDIA5 HLA-C PSMC3 PSMA2 PSMA7 SERP1 PSMB5 PSME4 PSMD14 PSMB6 PSME2 GGA3 PSME1 TAPBP PSMB9 PSMB2 PSMC2 PSMC5 PSMC1 ATF4	0.00312358	DOWN
HUMMERICH_SKIN_CANCER_PROGRESSION_DN	MYL9 DES TPM2 HSPB7 PDLIM3 SERPING1 FHL1 GPNMB C3 MFAP4 AEBP1 GPX3 LAMB2 PYGM DUSP14 LGALS1 LTBP3 ACSL4 COL6A2 C1QA CHST11 COL16A1 ELOVL4 PKD1 CD34 ZYX IL11RA BCAM ILK GJA1 NRP2 CDC25B ENO3 COL3A1 TCAP GLI1 TNNT3 PRKACA TNNI2 MYBPH TXNIP STMN1 MYL1 DST HP AES PTPRS RECQL5 MYH8 UBE3A PSEN2 GAA PIK3R2 MYH4 ATP5E PCDH12 MAPK7 ID2 GTF2H4 EFNB1 SPTBN1 EPHB3 FASN B2M BMP1 PDGFRA MYH1 CRAT CUX1 CXCL14 ATP6V0B ATP5L PPP1CB TNNC2 GGT1 ECSIT EPHA1 ATP5J2 ATP5C1 ECH1 PRKCI RPS6KA1 SCP2 HADHB WWP2 PC EYA2 MB LCMT1 FECH SMAD4 UBE2A ECHS1 PTPRF ACSL5 ECI1 DSG2 ACADSB	0.00313265	UP
PEREZ_TP53_AND_TP63_TARGETS	EGR1 CRYAB REEP1 FGF13 NEFL PALMD ID4 ZCCHC24 TSC22D3 EGR2 RHOB FRY NOTCH3 CDKN1C SLIT2 MOXD1 LBH CRISPLD2 NUAK1 NPTX1 MAN1C1 FOXF1 FOXF2 CX3CL1 ARHGEF6 SASH1 RASGRP1 NGFR COL18A1 KLHL21 MAFB ARHGEF17 GRK5 KCNK3 GPR37 PPP1R16B RET ADAP2 CELF2 NLRP1 SEMA4D TACC1 RBM38 KIAA1644 TOX KCNJ12 ST8SIA2 MEGF6 CHST2 BAMBI GABRE SMAD9 GALR2 MAF COL9A3 IGFBP3 TRIM8 RAB11FIP3 FGF18 ULK1 NPPC RORA STAR APC2 BLMH MXRA5 ITSN2 WNT7B KSR1 MX1 HUNK AQP3 CAPN3 NTN1 IRX5 PGF ULBP2 DPYSL4 MICALL2 FZD1 BCOR GRTP1 TMEM63A CITED1 HIC2 HS6ST1 LY6D PCSK5 NBPF1 SMAD6 FAM46C RAB11FIP4 PPP1R13B ADCY1 CASZ1 ID2 TM7SF2 EVPL EPHB3 MGEA5 CKB PAK6 TNFRSF10D UNC5B IGF1R CXCL14 ZNF750 ABHD6 BCL2L11 DHRS3 SMAD7 PTX3 PLCD1 BIK ARG2 MYLIP INSR AUTS2 HR ARRB1 IHH GNA11 PGAP1 PTPRJ TAF5 LONRF3 EPB41L3 DOK4 BMP2 EPPK1 HIST1H2BG APAF1 FAM105A SERINC5 VDR TUFT1 MARCH3 HSD11B2 RAB11FIP1 GMCL1 CNNM4 EPB41L4B	0.00314513	UP
BIOCARTA_MONOCYTE_PATHWAY	SELL ITGAM PECAM1 ITGB2 ITGA4 ITGAL ICAM1 SELP CD44 SELE ITGB1	0.00316258	UP
ONO_AML1_TARGETS_DN	CXCR4 CCR7 SELL CD81 CREM RUNX3 CD2 SOCS3 CCR2 IGFBP4 CD84 PARP1 CDK6 RUNX2 TNFSF8 IRF4 CCR5 TCF3 RBL1 CASP4 IL10 IL21 CXCR3 TNFRSF25 IL17A FFAR2 CCL5 FOXN3 IL4R CCR8 IL17RA ITGAE IL4 SOCS2	0.00316704	UP
VALK_AML_CLUSTER_9	MYH11 MN1 TPPP3 NRP1 CLIP3 COLEC12 CD1C FCGR2B SPARC CD81 PTPRM RUNX3 RPS6KA2 VSIG4 CBFB CHST12 AK5 CLEC10A MSLN ICAM4 TGFBI NDE1 CHI3L1 BAHCC1 EMID1 CD59 ST18 DHRS3 NT5E CLIP2 MGLL FAM171A1 FAM105A MTMR11 PAPSS2	0.0031711	UP
ZHOU_TNF_SIGNALING_30MIN	CYR61 EGR1 PTGS2 IGFBP5 DUSP1 JUNB PTMS IL6 IER2 CXCL1 TNFAIP3 KLF10 NFKBIA HSPB1 DDX56 ATF4 RPL10 CD5 SF3B2 EEF2 HNRNPU SLC39A1 TUBB4B CTNNB1 COPS2 KALRN ATP5G2 TUBA4A MAP2K1 KRT14 MCM7 TMF1 CDC123 TAGLN2 PPP2R1A PSMB7 NDUFA13 SIGMAR1 HDLBP ERGIC3 HMGA1 TRAP1 PLP2 CLIC1 TMBIM6 PRDX2 PHB IFI27 PIR	0.00317132	UP
REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC	TUBB2B TUBB6 TUBA1A TUBB2A TUBB4A TUBB3 TUBA1B TUBA3C TUBA1C CCT3 CCT4 TUBB1 CCT7 TUBB4B CCT2 TUBA4A CCT6A CCT8 TCP1 CCT5	0.00317508	UP
LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN	AOC3 TSC22D3 RHOB STXBP1 AP1S2 PMP22 PBX3 TRPS1 PER3 RCAN2 TGFB1 DPYSL2 MS4A4A ACSL4 EVI2A MYO5A LMO2 SCD5 PNMA1 ARL4C PSIP1 CLIC4 ALCAM BACE1 ITM2A ANXA5 PALLD CD302 CTNNAL1 GLIPR1 MAFB CELF2 DAB2 SOCS3 CYBRD1 CYBB ZAK NOV PRKCQ C3AR1 GSN PTGES GABARAPL1 HABP4 RNF41 TMX4 SGK1 DUSP22 CDK5RAP2 TES DCBLD2 TBC1D8 RASSF8 NUDCD3 GSTA4 ZFAND5 MBNL1 ARMC8 NGRN SETX SET TGFBR1 LYZ RNF38 DDX3Y IARS PQLC3 ISCU ST6GAL1 IFITM1 SON PRPF4 UGCG SGCB SDCBP CNN3 DNAJC10 SERF2 C9orf78 PSMB7 DNAJB9 AK1 PPP6C TGOLN2 MT2A GNAQ PSMD5 KIF2A FUBP3 POLE3 ERP44 MT1X MT1H RAB21 MT1E RNASE4 FBXW2 SCML1 RCAN1 RAD23B TMOD1 PLAGL1 ALDH2 BMP2K ISCA1 LIG4 SLC31A2 RAB14 HIST1H2BD NFIL3 IQGAP2	0.00323745	UP
DELACROIX_RAR_TARGETS_DN	OGN TPM2 TIMP3 PALMD FSTL1 NRP1 CCND1 LSP1 GJB5 ECHDC3 AQP5 CTBP2 SNTB2 FUBP1 CKB KITLG UBE2C GAS2 FGFR2 EMP1	0.00324586	UP
KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS	HMGCS2 PDSS1 HMGCR PDSS2 HMGCS1 ACAT1 DHDDS IDI1 FDPS ACAT2 PMVK GGPS1 MVD MVK IDI2	0.00340827	DOWN
REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS	CSGALNACT1 DCN CHST15 CSPG4 CHST11 CSGALNACT2 BGN CHST3 CHST12 CHSY1 CHST7 CHPF BCAN VCAN NCAN CHPF2	0.00340964	UP
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR	E2F8 MAD2L1 RFC5 CENPA TTK NEK2 GMNN KIF11 CCNA2 CEP55 HMGB3 DLGAP5 DTL KIF20A EZH2 TPRKB FABP5 SMC2 FBXO5 LMNB1 PAICS RAD51 NUSAP1 DCTPP1 RACGAP1 KIAA0101 TOPBP1 KIF22 GINS2 CDCA8 CDT1 MCM2 BRCA1 WDHD1 DSN1 DNAJC9 QSER1 HAUS3 FAM64A H2AFX DEK TIMELESS DCLRE1A NUP88 LBR MCM7 DTYMK HMGB2 USP1 KNTC1 CHAF1B CDK2 RAD54L MCM6 RPA2 EXO1 MCM5 GPN3 RANBP1 PSMC3IP TRIP13 MCM3 KIFC1 MAGOHB E2F1 NCAPH2 GINS3 MYBL2 SEMA3B RFC4 FAM198B SAP30 F10 SOD3	0.00344597	DOWN
NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_DN	CAP2 CDKN1C TCF7L1 OBSL1 FBXL2 CA11 BCL2 GNAS TP53 WRB COL4A5 SUB1 ITM2C	0.00348649	UP
BIOCARTA_LAIR_PATHWAY	C7 C3 VCAM1 ITGB2 ITGA4 ITGAL ICAM1 SELP IL6 C5 C6 SELPLG ITGB1 IL1A KNG1 TNF	0.00354648	UP
WESTON_VEGFA_TARGETS_12HR	MGP GEM CCL2 NNMT SGCE RHOB ELN CFHR1 VCAM1 COL6A3 THY1 COL1A2 VIM BGN COL5A1 MMP2 UBD IGFBP3 BDNF TFPI2 OXTR MMP3 SLC6A8 ANKRD1 SDC4 SULT1E1 SP3 SAT1 AQP7 FUCA1 MEST FGFBP1 F2RL1	0.00358978	UP
MORI_MATURE_B_LYMPHOCYTE_UP	CR2 SELL MS4A1 PEA15 IL10RA ARHGEF3 PIP4K2A HLA-DOB EBI3 PTPRC ADRB2 LAT2 LY86 LCP1 FAM65B HLA-DQA1 CTSH NCF4 HLA-DMA CD83 GPR65 MACF1 ADCY7 HLA-DRB1 SAMHD1 CXCR5 BARX1 HLA-DMB ZFP36L1 MYCBP2 CD40 CD74 SLC4A7 PTPN6 MEF2C LPP FCER2 FOXD4 GGA2 ETS1 APOE MAP3K8 RGS14 IRF8 B4GALNT1 ADD1 DGCR6 IL2RG RASA3 MCL1 POU6F1 WDR43 ABCA1 HLA-DOA PHTF2 CER1 FAM102A YTHDC1 SH3BP2 PISD IFNGR1 JAK2 MAP2K1 CMTM6 RAP1GDS1 RAB8A HLA-G SDF2 VPS28 SORL1 ID3 MAN1A1 RMI1 CTSS AIM1 SGPP1 IL10RB TMOD3	0.00379439	UP
BIOCARTA_DNAFRAGMENT_PATHWAY	CASP7 ENDOG CASP3 TOP2A DFFB TOP2B HMGB2 GZMB HMGB1 DFFA	0.00380732	DOWN
WATANABE_COLON_CANCER_MSI_VS_MSS_DN	CYP2B6 OLFM4 HMGCS2 ACE2 A1CF CHP2 PIGR SPINK1 VAV3 SLC26A2 CFTR KRT20 DACH1 CEL SEMA5A RIT1 PDK3 EBP FABP1 TNMD SLC26A3 APOOL TMEM106B TOB1 CD9 PRPS2 GPSM2 GRM8 CDC42 SYK POLR3E B4GALT1 WIF1 CXCL14 IGF1R USP53 PDS5B MYEF2 ZMYM2 PTCD2 CDHR1 CBX5 GNG4 SLC1A7 MUM1 NFIB INO80D TMCC1 CADPS KRT23 DUOX2 GPR143 ACSL6 EIF5A RBM6 LY6G6D SEPT7 NME7 STAT5B PCP4 REEP1	0.00384818	DOWN
BILBAN_B_CLL_LPL_DN	FOS RGS2 ANXA1 DUSP1 PRNP JUNB FYN ARHGEF6 FCRL2 ZBTB20 IER3 MS4A6A TCF7 MNDA FGL2 HOMER3 DUSP22 KLRK1 BIN2 CAPN3 MSL1 CCNL1 SUGP2 PNISR FNBP4 EIF4A1 PMAIP1 SRSF7 ID2 HMGB2 ARGLU1 CNTNAP2 SFPQ GLRX SORL1 SAT1 KLF4 ACAP2 MARCKS SULT1A1 HIST1H2BG	0.00385253	UP
BURTON_ADIPOGENESIS_5	HIST1H2BC PPARG ABHD5 CPT2 AGT CEBPA HK2 PEX11A AIFM1 FDX1 ACADM SCD AK2 GK MAPK6 LRRC59 SDHD TIMM8A IVD BCL2L13 MDH2 POR ECHS1 MGST3 CYC1 PHB CISD1 TMEM97 GPHN DBI ACO2 PPIF GRPEL1 FABP5 TOB1 COQ9 PC CYCS SCP2 NDUFA8 MRPL12 RPP14 RREB1 MTX2 MRPL15 ESRRA ETFB LMAN2 PTCD3 PSMA5 TBL2 SOD2 MRPL34 TALDO1 COX6A1 TIMM17A GPI PRDX3 ALDOA NRIP1 NDUFAB1 TMX2 UQCR11 PDIA6 BCAP31 XBP1 MRPL20 PSMA1 G6PD COX17 GNPAT MRPS34 MRPS2 PHB2 DNAJB9 CRAT PPA1 ACSL1 PTGES2 CLOCK SLC1A5 C18orf8 SLC5A6 MKNK2 IFNGR1 TIMM23 TOMM40 GYS1 ADAM12 TIMM9 LPIN1 LIPE SIPA1 EXTL3 CBR3 PRPS1 SORBS1 C3 IGF2 PTRF FABP4	0.00385551	DOWN
OHGUCHI_LIVER_HNF4A_TARGETS_DN	UGT2A3 SLC3A1 DDC HSD17B2 SULT1B1 RARRES1 AGMAT TMEM30B SLC30A10 SRD5A1 OTC BDH1 ERBB3 AQP8 ABCC6 PERP ETHE1 ABAT CEACAM1 C4BPA GCHFR QPRT SERPINA1 LIPC TPMT RDH5 FAAH EGFR FAM35A S100A10 F12 PCYT2 UGT2B4 HEBP1 APOM B3GALT1 AADAC CIDEB XYLB ACSM1 C8G CLDN1 C8A IL1RAP SAA4 TMC7 FABP2 NR1I3 SPP2 DIO1 CYP2F1 SPATA2L MCM10 SLCO2B1 SLC17A3 MBL2 GCGR SOAT2 CYP2C19 SHMT2 NOX4 HAAO GLYAT F13B BAAT SERPINA4 ALAS2 MTTP C9 F11 SLC22A7 CYP7B1 APOC2 SARDH PRODH2 C8B ASGR1 CA5A PROZ ENPP3 MASP1 ACP5 HAO1 CFI CPN2 ALDH8A1 TFPI2 SLC27A5 NUDT7 PDZK1 C6 BBOX1 TFR2 HRG KMO KCNN2 ADRA1B PRKD3 RARRES2 LIFR SLC47A1 CTSH SERPINF1 CFHR1 MPDZ	0.00386366	DOWN
VERRECCHIA_EARLY_RESPONSE_TO_TGFB1	TIMP3 IGFBP5 RHOB NID1 FN1 LAMA4 RHOQ COL6A3 COL1A2 SPARC ITGB2 LRRC17 PCDHGC3 CDH6 TIMP1 COL6A1 ICAM1 ZYX CD44 HSPG2 SERPINE1 WNT2B MMP19 IGFBP3 COL3A1 NOTCH2 CD82 RHOG MMP14 MMP3 LRP1 VCAN MMP16 DVL1 SSR1 MARCKSL1 ARHGDIA NME1 RPSA EPHB3 NME2 ITGA3 RND3 CYTH2 RHOA CD59 PXN ITGB5 PLAT TCF7L2 IGF2R APC ADAM9 JUP IGFBP2 PAK1 BSG	0.00388927	UP
REACTOME_DNA_REPLICATION	MAD2L1 RFC5 CENPA GMNN CCNA2 GINS1 ORC2 KIF20A ZWINT CDC20 ZWILCH PPP2R1B PSMC6 SPC25 CDC6 NDC80 BUB1B CDC7 FBXO5 PSMB8 KIF23 CDKN1A CENPN ORC5 PRIM2 ORC4 KIF2C POLD4 NUP37 PSMD3 PSMA5 ZW10 SKA1 GINS2 PSMD7 MCM4 PSMD13 PSMB10 CDCA8 SEH1L CDT1 PSMD10 ORC1 MCM2 KIF18A PPP2R5A PSMD11 GORASP1 PSMA3 RFC2 PSMC4 PPP2CB PSMD8 NUP85 BIRC5 RPA3 PSMA6 PMF1 DSN1 KIF2A PPP2R5E POLE2 PSMF1 AURKB PSMD5 PPP1CC PSMB3 NUP107 PSMA1 PAFAH1B1 PSMA4 RFC3 PSMD9 PCNA SEC13 SMC1A NUP133 NUP43 CCNA1 CENPM STAG1 PSMC3 PSMA2 SMC3 PSMA7 BUB1 NDEL1 PSMD1 ITGB3BP PSMB7 RAD21 PPP2R1A E2F2 RANBP2 POLA1 PSMD2 PSMB5 ORC6 POLD2 AHCTF1 PSME4 PSMD14 LIG1 BUB3 PSMB6 POLD3 MCM7 PSME2 PPP2CA B9D2 CDKN1B PSMD12 PSMB1 DBF4 PSMD6 CKAP5 PSME1 E2F3 RB1 PLK1 DNA2 ERCC6L FEN1 PSMB4 PSMB9 KNTC1 NSL1 GINS4 PSMB2 MCM10 PPP2R5D RPA1 PSMC2 PRIM1 PSMC5 CENPQ MIS12 STAG2 INCENP PPP2R5C MAPRE1 CDC45 RPS27 PSMD4 CENPO PSMC1 ORC3 CDK2 MCM6 RPA2 RPS27A RANGAP1 TAOK1 POLE XPO1 MCM5 RPA4 POLD1 UBA52 MCM3 CENPT NUDC E2F1 CENPI PPP2R5B RFC4 POLA2 CLASP1 CLIP1 MAD1L1	0.0038912	DOWN
LEE_EARLY_T_LYMPHOCYTE_DN	AMIGO2 GPR183 KLF2 CCR7 EMP3 S1PR1 GIMAP4 MAN1C1 ACTN1 CD27 CYTIP GPR171 IFITM2 SLC2A3 SEMA4C SAMHD1 CD44 IL27RA NELL2 ATM LRRN3 PIK3IP1 ANKRD55 FOXO1 RNASET2 MAP3K1 TNFRSF25 PRMT2 STK17A CYLD IFITM1 IL4R TUBA4A TBC1D4 HLA-E HLA-C DENND2D HLA-B HLA-A HLA-F LDLRAP1 SCML1 PTPRJ TNFSF10 ANK3 IL6R	0.0038985	UP
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN	TIMP3 IGFBP5 DDR2 TGFBR3 PMP22 IGFBP6 SPP1 COL5A2 ANGPT1 COL4A1 GNG11 CX3CL1 COL4A2 ALCAM CDH6 RUNX3 GATA3 PELO LHX1 RET DAB2 CDH11 COL5A1 MYC TGFBR2 INHBA BMP7 KLF10 APOE AGRN RARG FZD1 GPC4 DPEP1 DLK1 ITGAV PDGFA IGF1R VEGFA FRZB THBS1 EGF SEMA3C LETM1 ERBB2 ITGA2 CDH1 AGT SDC1 TGFA	0.00389985	UP
MORI_PRE_BI_LYMPHOCYTE_DN	KLF2 MS4A1 CD79B RHOQ S1PR1 IL10RA FCGR2B ZFP36 PTPRC BTG2 LY86 CYTIP BLK CD2 CD72 ADCY7 CD22 SAMHD1 TRAF5 LSP1 CD74 FBXO11 LYN RGS14 BIRC3 MCL1 FAM3C BTG1 JARID2 CNR2 TK2 PTK2B RBM39 IL4R AKIRIN1 TANK UBE2H CLK1 RALGPS2 ERP29 CASP9 TRAF3 HLA-G ATP6V0B GNS PNRC2 TSNAX ABLIM1 LPGAT1 NFKB1 ATP6AP1 ZCCHC6 UBP1 SAT1 TMEM50B CAPN1 NBR1 AIM1	0.00390367	UP
LUI_THYROID_CANCER_CLUSTER_4	PCP4 PLTP FGFR1 IL23A HLA-DQB1 HLA-DRA HLA-DPA1 ZYX HLA-DPB1 CD74 WARS NUPR1	0.00391025	UP
ROSS_ACUTE_MYELOID_LEUKEMIA_CBF	MYH11 MN1 RHOB CAV1 CRIP2 RUNX1T1 BLVRA ATP2B4 WFDC1 WIPF1 ROBO1 JUNB ADARB1 SPARC LAT2 TPSB2 DUSP2 CD52 HLA-DPA1 EGFL7 BAALC CD34 TMEM43 ADCY7 DUSP6 CBFB C11orf21 RCBTB1 HLA-DMB HLA-DPB1 GALNT14 HYAL2 STK32B SYNGR1 TPSAB1 VAMP5 CIITA TRIM8 PRAME RASA4 HOMER2 CCND3 TRH OGG1 PTGIR BAIAP3 TBXA2R POU4F1 DEXI CACNA2D2 ISG20 CLEC5A HIF1A NARFL KDM4B PURA C15orf39 IL5RA PMAIP1 IL15RA MKNK2 PI4KA NCALD PTGER2 DNMT3B TRIO SIPA1L1 ABR ITGB4 MAN1A1 CLIP2 CD58 DEPTOR HSD17B11 PGM1 SLC25A1 TPK1 HPGDS EGLN1 PSD3	0.00391797	UP
REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_	CLU MMRN1 SERPING1 CFD FN1 VEGFC F8 F13A1 TGFB1 SPARC PECAM1 VEGFB ACTN1 VWF TIMP1 TLN1 TGFB3 PROS1 PDGFB SRGN PRKCB SELP CALU A2M PPBP PLEK SERPINE1 LEFTY2 HRG FGB HABP4 HGF VCL PRKCA SCG3 ACTN2 PRKCG TGFB2 ITGA2B APOA1 SERPINF2 F5 CD36 FGA PFN1 PSAP ITGB3 ALB TF CALM1 TUBA4A CALM3 HSPA5 CD63 TMSB4X CALM2 PPIA FGG PDGFA WDR1 CAP1 PLG CFL1 VEGFA APP PF4 THBS1 STX4 KNG1 ACTN4 SOD1 ALDOA EGF STXBP3 CD9 ABCC4 SERPINA1 LAMP2	0.00391826	UP
RODRIGUES_THYROID_CARCINOMA_DN	DMD AMIGO2 ARHGAP29 THBD FN1 SLIT2 KCNMA1 QKI DUSP10 BNC2 PLCB1 ROBO1 ZNF512B ALCAM CREB5 SRGN HIVEP2 CXCL1 CDC42EP3 CD44 PMEPA1 BBX MAP2 AREG CDK6 BBC3 ZNF160 DCBLD2 L3MBTL1 ATXN1 GMEB2 PLEC EFNA5 ITGB8 HIPK2 DICER1 F2RL2 MORF4L2 PCBP2 LIF SHANK2 S100A2 COL8A1 UGCG ZNF638 ARHGEF7 ANKRD10 TRA2A ZMYM2 CLDN1 PPP1R13L ARHGAP35 ZNF207 TAB2 THBS1 IRF1 IGF2BP2 ANKRD28 PAX8 PTPRK S100A10 RSF1 UBXN7 SAMD9 RIT1 NAMPT PGPEP1 ANK3 SYTL2 MYO1D	0.00392056	UP
RUIZ_TNC_TARGETS_UP	SCG2 STON1 KIAA1462 CLU FLRT2 ZCCHC24 CSGALNACT1 EDNRA MEIS1 CXCL12 LDB2 C14orf132 TRIB2 SPP1 ATP2B4 COL5A2 ROBO1 BCL6 VCAM1 OLFML2B LTBP3 CHST15 ACSL4 SLC16A4 FAM110B TDO2 COL1A2 IGFBP7 SNAP25 PTPN13 FOXF1 FOXF2 KCTD12 ZNF532 ARID5B EXTL2 TRO PDGFRB GDF15 DDIT4 PROS1 COL18A1 SSBP2 MAFB SNCAIP SLC2A3 PDE5A A2M PHF21A CDH11 RCBTB1 BAMBI ST3GAL1 NR2F1 LRIG1 LEF1 PNRC1 GSN TBXAS1 ENPP2 COL3A1 TIMP4 SLC23A2 APOE PHLDA1 TM4SF1 PLK2 SLC6A15 YPEL5 KLF9 KLHL24 GBP2 BTG1 C1RL RARRES3 C21orf91 EYA1 BTN3A3 CLCA2 WSB1 BTN3A2 IL1R1 PSAP HEY1 WDR26 COL4A5 ITSN1 MARCH6 BNIP3L NUMA1 TPP1 ID2 MAGED1 PDGFRA VGLL4 PCMTD2 HERPUD1 HLA-C CBLB LTA4H ARHGAP28 TCF12 GRN BAZ2B ALDH3A1 KRIT1 HBP1 SIDT2 CTSC GOLGB1 CTDSP2 BDH2 METTL7A UBXN4 SAT1 TNKS MAN1A1 SEMA3C IFIH1 KDM5B PDCD4 SLC35E2B ARRB1 SOX4 NBR1 FCGRT SLC2A10 SPTSSA CAT GPRC5C CTSA RAB17 GBE1 TNFSF10 EAPP SEMA5A TBL1XR1 ANXA4 ATP9A HPGD SELENBP1 HNMT IQGAP2 AUH WIPI1 IMPA2 RARRES1 GLCE	0.00392484	UP
SCHRAETS_MLL_TARGETS_UP	FOS PEG3 SDPR TNC ACTA2 FHL1 CADM1 DCN COL1A1 IFI16 NES TPD52L1 SERPINE2 CD34 NDN TNNT2 BTG3 MLF1 GM2A MSX2 GPC4 FOXG1 MMP10 TMSB4X CTSZ SUMO3 HOXA1 FZD6 CTSC FAS TOB1 TSPAN7 PERP TOM1L1	0.00392845	UP
LABBE_WNT3A_TARGETS_UP	CYR61 CTGF GREM1 AKAP12 STXBP1 CAV1 TUBA1A FBLN2 SPP1 HMP19 RDX AMOTL2 NRP1 TGM2 TGFB1 ROBO1 SERPINB9 PHGDH CPE PER1 SALL2 HHEX LY6E ALCAM LTB F10 PDGFB ZBTB20 FADS2 ADCY7 CEBPD CCND1 CXCL1 SHCBP1 PTPN6 SERPINE1 C6 SGK1 PRMT1 AHR ECM1 IL2RG TNP1 GSTM3 NFKB2 HS3ST1 DNMT1 MMP14 DCK TUBA8 SIVA1 TUBA1B DUSP8 GNAS MCM6 RBBP7 ACTB CAV3 PRIM1 MTMR1 SCGB1A1 GPLD1 POLR2B SAA4 RRM2 TNNI1 GSTM1 WDR77 POLD2 IFIT3 LMNB2 ANKRD1 PCNA GADD45G ALDH1A1 TAT KPNA2 PTPN21 ID1 CTSC NFAT5 ADD3 BAG1 CDK1 S100A10 ATP5J2 NIT1 MCM4 RACGAP1 RSU1 HELLS FABP5 LY75 CD24 NMT2 MKI67 CCNB2 DDT CCL13 TOP2A TSPAN7 TMPRSS2 HMGB3 AURKA SGK2 CCNA2 CA2 ECT2	0.0039309	UP
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_6	MGP GUCY1B3 AMIGO2 LOXL1 SACS SERPINA3 ITGB2 MCTP1 AOX1 KMO IL2RB GSTM3 RNF32 PDK4 RAB27B TAF1A SOCS2 UGT2B28 CAMK2N1 CCDC68	0.00393356	UP
MARKEY_RB1_CHRONIC_LOF_DN	UCHL1 ACTG2 MLLT11 TIMP3 TFPI CCL2 RHOB NDRG4 HTRA1 CADM1 DCN CCL3 GNG11 CP LMO2 C1QA PTPRC NPR3 CSF1R ENAH TYROBP TRPV2 RPS6KA2 TPD52L1 CD53 SRGN IL6 CFP LCP2 C1QB SPI1 MS4A6A TPH1 PSTPIP1 GABRB1 RBP1 VAV1 SYNGR1 PLA2G7 C3AR1 STAB1 IRF5 NGF GABARAPL1 NINJ1 SLCO3A1 IGFBP3 ACTA1 PLD3 RASL11B APOE ADAM8 TGFB2 CCR5 CD14 NUPR1 ZDHHC14 IFI30 GSTA4 RENBP GJB3 WISP1 IVL CRCT1 MMP13 TEC SLC1A6 UPK3B MSR1 FBXO9 FABP7 DCTN6 RABAC1 MMP12 RB1 ARL5A SQSTM1 ATP6V0B CA3 EGFR PRDX2 KDM5B MCCC1 RNF19B SKAP2 EDN1 UBFD1 UBE2A SEPT11 PARM1 PON2 CTSS PLIN2 LGALS9 IGFBP2 PRRC1 PLAC8 KRT18 HMOX1 HPGD MEST HIST1H2BC	0.00393555	UP
REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX	GMNN ORC2 PSMC6 CDC6 PSMB8 ORC5 ORC4 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 CDT1 PSMD10 ORC1 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 ORC6 PSME4 PSMD14 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 ORC3 RPS27A UBA52	0.00394308	DOWN
MORI_LARGE_PRE_BII_LYMPHOCYTE_DN	MS4A1 WIPF1 CD79B VCAM1 IL10RA PIP4K2A PTPRC LAT2 LY86 LCP1 FAM65B DOCK2 HLA-DQA1 LTB CTSH HLA-DMA CD83 GPR65 MACF1 ADCY7 CD22 SAMHD1 CXCR5 SEMA4D HLA-DMB CD40 CD74 PTPN6 SIPA1 LPP GGA2 RGS14 IRF8 BIRC3 IL2RG RASA3 MCL1 GMIP BTG1 CNR2 HIP1R UBA7 IL4R TAPBP ITGAV GNS CAPG CAPN1 ALDH2 CTSS AIM1 SERPINB1 SOAT1	0.00398805	UP
HOWLIN_PUBERTAL_MAMMARY_GLAND	OGN EGR1 THBS2 APOD CFH CXCL12 CD37 ANGPTL2 VPREB3 PENK GAS7 FCGR2B EVI2A ADARB1 NPR3 LIMD2 TWIST1 COL18A1 INHBB HSD11B1 SFRP4 PTN LSP1 AOX1 RECK DBP AREG S100A9 APBB1IP PRRX2 CALML5 MARCO SLC6A6 COMT CITED1 EPS15 GSTA3 MSR1 HAL CTSB CCL7 SMS PI4KA USP15 PDGFRA KRT10 PTEN TNF KLF4 IDI1 EPS8 SLC30A1 NFIL3 ELOVL6 REG3A PCK1 IL1R2 PROM1 FOXA1	0.00402715	UP
HASLINGER_B_CLL_WITH_MUTATED_VH_GENES	DMD MAL PCDH9 LPL LPCAT1 IL10RA LDOC1 P2RX1 ZBTB20 TCF7 KLK2 TLE1 COBLL1 SORL1 NRIP1 PCSK7 SEPT10 WSB2	0.00406668	UP
SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP	ASPN FABP4 TAC1 PDLIM3 RGS2 EPHA3 EFEMP1 CYP1B1 TMEM100 FZD7 COL5A2 PLCB1 BNIP3 SETBP1 MAOB COLEC12 BCL6 VCAM1 PENK MAFF PFKFB3 MAP3K6 FOXF2 TMEM45A ARHGEF26 LMCD1 NLGN1 LAMA5 PROS1 TFAP2C ALDH1A3 CEBPD LMO4 PDGFC KCND2 MAF FKBP5 STAT5A ARC TP63 RASL11B AHNAK EMD DCLK2 KLF9 CALCRL PLA2G4A NCOA1 GLUL SHH RPL35A WWP1 MYF5 TAF1D LY6D ABI3BP KLF15 PMAIP1 CIDEA ARL6IP5 TLE1 AVPR1A PGAM1 SESN1 HSPA1A CXCL14 WIF1 GADD45G LRRK1 COL4A6 SNRPD3 STK17B FNDC3B UBE4A ITGB4 BDH2 PGK1 NT5E ADAMDEC1 RALY SLC2A1 ATP1A1 PDGFD SOX9 FGFR2 PID1 IGFBP2 TRIM2 MPST VWA5A TSPAN1 CDH1 LAMP2 EGLN3 CEACAM1 SLC39A8 LRP4	0.00406976	UP
REACTOME_MEIOTIC_RECOMBINATION	HIST1H2BC HIST1H4H HIST1H3H HIST1H3D HIST1H2AE HIST1H2BH HIST1H2AC RAD50 HIST1H2BD HIST1H2BG RBBP8 HIST1H2BE HIST1H2BI HIST1H2BF RAD51 HIST1H3E HIST1H2AJ HIST1H2BM HIST1H4K HIST1H4B MLH3 HIST1H3A HIST1H3F BRCA1 HIST1H2BK HIST1H4J BRCA2 HIST1H4D HIST1H2AD RPA3 HIST2H2AA3 HIST1H4F MRE11A HIST1H3B MSH5 H3F3A H2AFX HIST1H4C HIST1H2BO HIST1H4L HIST2H4A HIST1H4A HIST2H2BE HIST1H3G HIST1H2BB HIST1H2BJ H2AFZ HIST1H4E RPA1 HIST1H4I MLH1 TOP3A NBN CDK2 RPA2 HIST1H2AB HIST1H3I HIST1H3C SPO11 DMC1 BLM TEX15 H3F3B CDK4 HIST3H3 PRDM9 MSH4 HIST1H2BN HIST1H2BL HIST1H3J RAD51C ATM	0.00421942	DOWN
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN	FAM129A SOBP DLC1 OLFML3 FBLN1 NAV3 PMP22 TRIB2 ISLR FAT4 FZD7 MFAP4 EFEMP2 OBSL1 EMP3 TRPS1 COL5A2 GLT8D2 COLEC12 EMILIN1 SLC43A3 NUAK1 RGL1 FAM110B RGS10 RBMS3 FZD4 SH3BP5 ZFHX4 PTPN13 C1orf54 OLFML1 KCTD12 TMEM45A LAMA2 LY6E NRXN2 CD248 ITM2A BST2 LHX6 PDGFRL NNAT CRTAP SNCAIP SCARA3 IER2 SLC1A3 PLAG1 PARVA CRABP2 CCND1 DUSP7 PTN HIF3A ADA DUSP4 MMP2 LPAR1 SERPINH1 LTBP4 PTP4A3 CHMP7 EPHB4 PRAME TP63 WNT11 CYP26B1 EHD1 SEMA3B PLK2 MFAP2 AMPD2 EEF1D ZFP36L2 CSRNP3 TRIP6 ZNF16 PTH1R FAM160B2 PVALB MAGEL2 SORBS3 RHOG CACNA1G ZIC1 KAZN TSSC4 EIF4EBP1 DOK1 PRR16 BOP1 HOXC6 GPC4 MGAT1 CITED1 ERF TSPAN9 HOXC10 OCA2 MYF5 HOXC11 NBN AKIP1 NYNRIN KAZALD1 PTGER4 HEY1 GSTM2 TNFRSF1A FKBP11 TRIP10 SIGIRR RHBDF1 WLS ID2 BMP4 SLC1A5 EPHB3 TRAPPC9 CCDC25 BMP1 GSTM1 CDC42EP4 EXOSC4 TRIL TSTA3 GALNT2 GPAA1 GULP1 OPLAH TPBG RRBP1 MAPKAPK3 APLP2 FNDC3B SOSTDC1 IGF2BP2 GAS2 CTDSPL EXT1 ASAP3 ARL4A EGFR REEP4 CREB3L1 GMPPA ITM2C PGRMC1 TSKU NCOA2 ARHGEF40 FABP5 KHNYN DENND2A HOXA10 PLBD1 ERBB2 FBN2 RAB32 INPP4B SLC39A14 SLC39A4 DENND1A CNNM4 SDC1 HMGA2 CPM PSD3 STEAP1	0.0042521	UP
BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN	TLR3 CYP4F11 GCLM SLC16A1 SLC39A8 CDC14B GCHFR AK2 TRIM2 ABCB1 SDHB ABHD2 AIM1 GBE1 CTBS TMED5 COQ9 GCLC GLRX SPSB1 HMOX2 ZNF330 C14orf159 ALDH1A1 ACYP2 GADD45A LAP3 HSD17B10 KAT2B CTSB BTN3A2 BLCAP BTN3A3 MBNL2 ZNF593 CYP7B1 PRSS53 KLF9 VKORC1 MPDZ	0.00434073	DOWN
DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN	CCL2 OLFML3 RGS2 NEFM TRIB2 MOXD1 PKIA TCF4 DUSP4 MSTN IGFBP3 PHLDA1 PLK2 ZFP36L2 MYLPF ATP2A1 TRIL SPRY4 TNNC2 GAS2	0.0043423	UP
CHANG_POU5F1_TARGETS_UP	CYR61 AOC3 FN1 SLIT3 TGFB3 COL5A1 COL3A1 OPHN1 MMP13 KAT2B SMARCA4 ATAD2 VASP ABI1	0.00434924	UP
REN_ALVEOLAR_RHABDOMYOSARCOMA_UP	DES CASQ2 TUBB2B KCNN3 NCAM1 TPPP3 CDKN1C PTBP2 PDE2A SLC24A3 MEOX1 SCN3B MAB21L1 SGCA CNR1 VWF TGIF2 NES ITM2A PLXNC1 PKIA PCDH17 DMPK JAG2 RTN2 PPP1R16B CELF2 RASSF4 ZNF536 RBM38 SOX11 CYFIP2 PIPOX MYOG BIN1 ENO3 TNNT2 TFAP2B CDH15 ARPP21 ALPK3 DIO2 POGZ MYOD1 NHLH1 TNNT3 SIRT2 MYCN TNNI2 NCOA1 DCX CHRND RRAGD SIX1 RNGTT MYLPF POU4F1 CACNA2D2 GNAS EYA1 RYR1 ATP2A1 CHRNB1 RPL31 ASXL2 HEY1 TNNC1 FOXN3 SYNPO2L SRSF7 NRCAM NCALD TNNI1 CHD7 PCMTD2 ATP2A3 POPDC3 PKP4 NDRG2 RAPSN CLCN5 SEMA6A TMOD1 EYA2 FGF9 FGFR4 SYNE2 IGSF3 TSPAN12 SPINT2 COBL AGPAT5 CEBPA ERBB3	0.0043645	UP
HAN_JNK_SINGALING_DN	OGN RGS2 PLTP C3 COL6A2 CP SLC29A1 SOD3 COL6A1 HSD11B1 LIFR GHR SOCS3 RBP1 CD74 IGFBP4 ISYNA1 LBP ENPP2 GDF10 SPIB AHR CD14 ABCA1 TAF1D IFITM1 CYP2F1 HAS2 MAP4K3 PAWR SEMA3C WNT6 FAS CD9 LCN2	0.00438984	UP
WORSCHECH_TUMOR_EVASION_AND_TOLEROGENICITY_UP	CCL2 CCR7 VPREB3 PIAS3 CX3CL1 IL7R IL6 CCL4 LCP2 IL2RG IL13 STAT4 CXCL9 IRF7 IFNB1 LY6D IL12B IL9 XCL1 PIAS2 CXCL10 IL4 IFNAR1 NFKB1 IFRD1 BLNK	0.0045598	UP
DASU_IL6_SIGNALING_UP	GEM CCL2 HTRA1 TMEM158 STMN2 TGFB1 EMILIN1 DNM1 MAFF RGL1 ZFP36 COL16A1 VEGFB LY6E COL6A1 ENG PLA2G4C TFAP2C IER3 PDPN IL6 CEBPB TNFAIP6 CDC25B PTGES NMB ZFP36L2 AGRN SORBS3 IFI30 MMP3 FCHO1 GAS6 PLEC CXCL3 SREBF1 SERPINB2 FAM189B IRF9 CD47 TAPBP HIST2H2BE FASN KHSRP HSPA1A MGRN1 IRAK1 HLA-F MAP2K2 SOD2 NAGPA SOX4 DNM2 CKS2 ATP2B1 MMP1 HIST1H2AC ANPEP	0.00459201	UP
MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_UP	GAS1 ANXA1 COL16A1 SRF GATA2 JAG2 LIPE DARS ABCA7 DCTN1 WEE1 CST3 NAA10 AP1B1 PSG2 FAH INPP1	0.00459457	UP
ODONNELL_TFRC_TARGETS_DN	ASPM ECT2 HMMR PRC1 CENPA KIF4A TTK KIF11 CCNA2 CEP55 AURKA CCNB1 DLGAP5 TOP2A KIF20A SCD CDC20 MKI67 FOXM1 TAF5 SPC25 CDC6 NDC80 BUB1B TFRC CENPF HELLS CKS1B DEPDC1 FBXO5 CDKN3 PLK4 CENPE ZBTB6 VSNL1 CDK1 SNX5 HIST1H3F SLC12A1 ARHGAP11A WHSC1 SAMM50 KIF14 BIRC5 BRCA2 NCAPH G3BP1 NUP50 SURF1 MYNN POLE2 AURKB BPTF GNAQ TOX4 ITGB5 BUB1 USP9X KRT35 RAD1 CD151 RRM2 RAD54B DCP2 DBF4 PLK1 DNA2 ERCC6L ACACA GALT DIAPH3 MEX3C C6orf10 SIX3 TUBD1 ASNS RANBP1 CHAF1A FETUB FUS USP29 GINS3 ACVR2B FGF22 SETMAR GTSE1 MYBL2 DSCAM TP63 TACC3 FKBP5 CPNE6 MAP4K2 SHCBP1 KCNA1 FAP APBB1 NRTN	0.00467247	DOWN
HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_DN	GPR183 SCN3A CFD TRIB2 CCR7 G0S2 F13A1 RAB31 CSTA LGALS1 SERPINF1 S100A8 CTSG CSF1R RNASE6 LY86 ARHGEF10 NRXN2 TYROBP PALLD LTB IL7R CEBPD MS4A6A PLEK NPTX2 MME LEF1 HGF MS4A3 ITGB7 PRTN3 IRF8 CCR9 CST7 CD7 VPREB1 ELANE HCK LYZ VCAN MPO HAL DNTT RRM2 LGMN TARP AZU1 SLC2A5 TNF TRAF4 CRIP1 BLNK MCM4 SPON1 CD24 CDC20 ZWINT IL6R KIF15	0.00468876	UP
BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP	FNBP1L TRIM31 MAD2L1 MPZL2 NRAS HMMR TTK SNX7 CCNA2 CEP55 MELK PLOD2 KIF1B SRI TXN UCK2 TBL1XR1 EML4 CANT1 ZWILCH RIT1 RAD51AP1 NDRG1 HN1 PGD LRRC59 TPD52 MRPL42 NSF AGA RPRD1A CYB5B USP3 PHB PSMC6 GMFB KIAA0196 CDC6 EZH2 LRP12 NDC80 TPRKB C5orf22 PHLDA2 SEC61G MARCKS KIF2C NUP37 TMX1 NPEPPS NCAPD2 EBNA1BP2 GOLT1B TOPBP1 FTH1 TGIF1 COIL PUS7 PGK1 WDR12 SLC16A3 NARS PSMD11 PSMC4 AIMP1 PPP2R3C SLC38A6 CLIC1 PAPOLA NCAPG UBE2V2 GTF3C3 COPS5 SNRPA1 PIGF ACTL6A KIF2A SMAD2 EIF4A3 TDG DHX15 PRMT5 PDCD2 PPP1CC ATIC MED24 NUP107 CCT5 PTGES3 ENO1 RFC3 PSME3 HJURP NUP155 TSN SMC1A CSNK1D G6PD NOL11 CENPM UTP18 PTP4A2 BUB1 GPN1 GNL3 GLA RAD21 SLC7A1 FANCI HGS DNAJC10 PLEKHF2 PSMD14 TAF2 EIF2S1 HIST2H2BE DKC1 NLE1 HNRNPR LANCL1 USP14 CCT2 KDM3A RBBP4 NME1 SMG8 POLR2K SUB1 UGCG ACACA ENOPH1 TCEB1 IPO7 CKLF GNB1 PFN2 PRIM1 UBR5 CCT4 RPL8 FAM50A MAPRE1 TPD52L2 IPO5 ADSL BRD7 ARPC4 EIF3H CSDE1 RBM28 CBX3 DR1 XPO1 TMEM185B PWP1 CASC3 CCDC86 KPNB1 PAK1IP1 MRTO4 NGRN STMN1 TRIP13 BOP1 EIF3B SAP30BP SNRPD2 MED1 WDYHV1 PRKAR1A DUSP3 ARPP19 TIPIN TACC3 FXR1 MPV17 ANP32E MMD ITGB1BP1 KLC1 SRM ASAP1 LPCAT1 PTBP2	0.00470837	DOWN
REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS	SLC19A3 MOCOS ENPP1 SHMT1 TPK1 PPCDC PANK3 MOCS1 QPRT RFK NAMPT DHFR PDXK GPHN PNPO NFS1 PPCS SLC19A1 NADK NADSYN1 SLC2A1 CYB5A COASY PANK2 AASDHPPT MTHFD1 PANK4 GSTO1 FASN FLAD1 SLC5A6 MOCS2 THTPA MOCS3 FPGS SLC25A16 MTHFR SLC46A1 ACP5 CYB5R3 SLC25A32 SLC23A2 SLC19A2 SLC2A3 NMNAT2	0.0047328	DOWN
WIERENGA_STAT5A_TARGETS_GROUP2	RGS1 TUBB2B CCL2 KLF2 SPP1 CCR7 STAP1 BHLHE40 LAMP3 CCL3 BTG2 ARID5B CCL22 COL6A1 COCH IL7R CD83 GPR65 SLC2A3 PRDM8 SLC2A14 GABARAPL1 TSC22D2 TRAF1 PLAU CD1B PLEKHH3 CSF2 KLF6 OLR1 ABCA1 PHTF2 GADD45B PSAT1 CCL5 CXCL10 FPR3 EGFL6 CLEC4A SQSTM1 CKAP4 GNPTAB HOXB5 SOCS2 MOB3B NFIL3 GALC CA2 EMP1 MAPK13	0.00479875	UP
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_DN	CYP1B1 PMP22 IL10RA CAMK1 ENTPD1 HDC PDE4C GDPD5 PILRA ALOX5 MS4A2 CPA3 ADAM8 ALOX5AP FCER1A KRT86	0.0048042	UP
TSENG_ADIPOGENIC_POTENTIAL_DN	FABP4 AOC3 THBD DKK3 CAPN6 NRP1 HLX COL6A3 SPARCL1 COL4A2 COL6A1 PPL RAMP2 EPHB6 FMO1 B3GALNT1 CDKN2C LPAR1 GJA1 TGFBI IL6ST NMB PAX3 SNAI2 GSTT1 SIX1 ADAM23 ITIH2 IL1R1 CST3 ART3 TSC22D1 SMS SESN1 POPDC3 HSBP1 GAS2 RAB9A GHITM PHKA2 TSPAN6 ENPP1	0.00480422	UP
KATSANOU_ELAVL1_TARGETS_UP	KCNMB1 VNN1 PALMD POPDC2 FXYD6 MYH11 SERPING1 NOTCH3 CXCL12 LDB2 ADAMTS5 GPX3 FBXL7 TGM2 EPHA7 OLFML2B TCEAL1 EMCN RGS5 SLC16A4 CD200 SPON2 C1QA MYOM1 LAPTM5 FOXF1 IGF1 NES CD52 IFI44 GATM LAMA5 ENG GDF15 DMPK CTSH CERS4 PDGFB SSBP2 FOXC1 DAPK1 ALDH1A3 PDE5A STOM C1QB DUSP6 MMP2 CYBB KIF21B C3AR1 PTP4A3 CCL17 EPHA4 TNNT2 FJX1 GDPD5 GALNT11 SNCG RARB MYO7A APOE C21orf62 CDKL3 SFI1 SULT4A1 CDH10 ATP10D NUPR1 KLHL24 IL2RG CCL25 PAPPA2 FOXD1 TXNIP NFKBIE ALX1 RENBP HOXC6 SLC7A7 COL11A1 C9orf116 HIPK2 TNNC1 RPLP1 C19orf33 SCUBE3 ESD BMP4 PSME2 ITGA3 PLEKHA2 TCN2 GADD45A ANKRD1 ABLIM1 SFN ALDH1A1 TIMM8B DHRS3 MYL12B SLC25A17 SPSB1 FZD6 CTSC HN1L SAT1 IGF2R DDAH2 CCNG2 RABL2A IER3IP1 FAS HOXA6 TMEM223 AGA HOXA5 CTSS MOGAT2 IGFBP2 PGPEP1 PLOD2 HOXB9 DSP SORT1 SYTL2 CCDC68 MEST HOXB6 PITX2	0.00483301	UP
LEE_LIVER_CANCER_DENA_UP	FABP4 BCL2A1 RGS2 ANXA1 NOTCH3 LEPR LPL FBLN2 SPP1 VCAM1 PEA15 COL4A1 CPE POU2AF1 COL4A2 LY6E GATM ANXA5 LAMA5 MFGE8 PPBP PLEK GPC3 S100A9 TLR1 B4GALT6 NKTR APCS HOXC6 CSN3 TM4SF4 RAD51B MCM6 LY6D RPL36 MMP12 COL4A5 NUP205 VNN3 CD63 TAGLN2 IGFBP1 ANKRD1 LGMN PLAT THBS1 ID1 PTPRE KDELR3 ANXA2 DYNLT1 LCN2 CD24 SOX9 CTSS NDRG1 ABHD2 KIF11 TFF3 KIFAP3	0.00483854	UP
GROSS_HYPOXIA_VIA_HIF1A_DN	CYR61 FOS CTGF ATF3 ENO2 C8orf4 PRKCDBP CAV1 CXCL12 HBEGF BHLHE40 DUSP14 BNIP3 SAMSN1 PFKFB3 C10orf10 ZFP36 CACNA1H NPTX1 PPL CDC42EP3 VWA1 ATP7A PNRC1 KLF10 MMP8 MERTK SGK1 SKIL NFKBIA S100A13 DUSP3 LLGL1 FST PDLIM4 PGF DMP1 SIK3 POU6F1 TK2 MMP3 ZNF143 SETX SPRY2 FOXG1 PRPF19 TMPRSS11D SSX2IP GYS1 SHB RBPJL TOMM40 FOXO3 KLHL2 ARL6IP5 TIAM2 KIF5A MYH9 EIF1B SH3BP4 POLR2D VHL ANKRD1 GAPDH GADD45G ENO1 INSIG2 VEGFA TRAF6 LRP5 PSMC4 ADM LNPEP DAP MTCP1 MINK1 TGIF1 SLC2A1 KLF4 NPEPPS RPS6KA5 ACAP2 CAPN1 LMO7 EDN1 ME2 GPRC5C GBE1 HIGD1A CPD LXN TRAF3IP2 SELENBP1 SOAT1 IL18	0.00485265	UP
WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP	FOSB ATF3 NR4A1 SERPING1 FN1 TRIB2 CCR7 SMTN COL5A2 MMP9 C1R COL6A3 SFXN3 JUN GPRC5B ITGAM SLC16A4 THY1 IGFBP7 SPARC PECAM1 GNB5 LAPTM5 ICAM2 C1S CSF2RB DUSP2 LUM ANXA5 UCP2 CTSH DAPK1 HLA-DRB5 CD34 NOTCH4 CCL4 ARID5A CALU DUSP6 SOCS3 TNFRSF1B C4A TAF15 PMEPA1 TNFAIP3 IFITM3 SERPINE1 FMOD FCER1G TBXAS1 TNFRSF12A IGFBP3 COL3A1 MMP7 PIM2 CA6 FKBP6 AMPD2 ODC1 COL9A2 IRF3 IFI30 ECE1 ZNF593 RGS3 PNPLA2 BTN3A3 SSR2 IFITM1 EIF1 MMP12 ENC1 IFNGR1 NME2 MCM7 GSTO1 SETD3 IFT20 AQP9 CREB3 LGALS2 HLA-A PF4 ELF5 KNG1 SDC4 LASP1 DAP KDELR2 TCF7L2 HSD17B3 PIGT HSPE1 BAK1 MECOM GPX2 AGPAT2 GCC2 ANXA4 SRI LAMA3 KCNK1 ACAA2 PLS1 MEP1A TRIM31 GALNT3 PROM1	0.00489723	UP
KAN_RESPONSE_TO_ARSENIC_TRIOXIDE	MGP SCG2 FABP4 CRYAB ATF3 IGFBP5 GPM6B DPYSL3 ARHGAP29 ENO2 CAV2 TSC22D3 SACS TMEM158 ARHGAP6 GPNMB PPP1R15A MYBL1 PTPRZ1 ZNF512B JUN PHGDH GFPT2 PODXL KCTD12 ARL4C NES CLEC2B RGS4 GDF15 DDIT4 IL7R GPR65 HSPA6 VAT1 STC1 PTN PTHLH SERPINE1 STC2 GABARAPL1 LDLR PTPRO PHLDA1 DIRAS3 PLK2 KLF12 TRIB3 NDP SOX2 DCBLD2 DDIT3 NUPR1 IGF2BP3 GSTM3 C6orf15 IL11 BOP1 INSIG1 VCAN ASNS SLC7A11 PSAT1 TRIM16 FABP7 HEY1 DKK1 BNIP3L ATP6V0E1 ID2 FEZF2 EIF4G1 MCM7 JAG1 RRM2 PDGFRA MAP1LC3B CCPG1 CXCL14 ANKRD1 MT2A FAM64A GRN AK4 THBS1 SOCS2 GLRX ADM SLC12A1 SEL1L3 MT1X MT1H PGK1 MT1G MT1E MT1F LMNB1 EFNB2 FBXO5 FAM162A LGALS8 AKR1C1 SPC25 AKR1C2 NDRG1 SLC30A1 RIT1 SCD CBS KIF20A PIR TOP2A HMOX1 DLGAP5 NOX1 WIPI1 AKR1C3 AKR1B10 CTH	0.00490582	UP
FRASOR_RESPONSE_TO_ESTRADIOL_UP	FOS PEG10 EGR3 PTGER3 CXCL12 SDC2 CYP1B1 MYBL1 RAB31 OLFML2A MPPED2 MAPT RASGRP1 WISP2 RET IGFBP4 AREG SLC39A6 PDZK1 RFC4 GLRB HOXC4 CYP1A1 CALCR ADCY1 GREB1 PRSS23 SIAH2 NRIP1 ADCY9 CDC6 EPB41L3 TFF1 WWC1 CA12 TOP2A SLC22A5	0.00492503	UP
THUM_MIR21_TARGETS_HEART_DISEASE_UP	ASPN APOD COL5A2 ELN COL1A1 COL1A2 SVEP1 WISP2 LUM TGFB3 BGN LTBP2 CRLF1 LOX RCAN1 POSTN	0.00501145	UP
TIAN_TNF_SIGNALING_VIA_NFKB	PTGS2 CTGF GFPT2 ZFP36 CXCL2 TNFAIP2 TNFRSF9 IL7R CD83 IL6 CXCL1 TNFAIP3 CCL20 REL NFKBIA TRAF1 PLK2 FST NFKB2 NFKBIE CXCL3 RELB NFKB1 IRF1 SDC4 TNIP1 GCH1	0.00504461	UP
BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP	ADAMTS1 PLN GPM6A DMD PEG10 ID4 ADAMTS5 PCDH7 SLIT2 OMD TWSG1 CFHR1 TMEFF1 SLIT3 GNG11 CNR1 PRKAR2B PLXNC1 PCDH17 LIFR MDFIC LMO4 DPYD LRRN3 NR2F1 EPHA4 LTBP1 SGK1 CALCRL PBX1 FARS2 ACADL CITED1 GNAS STX11 KAT6B SCAMP1 TUBB1 CLSTN2 KITLG TPBG MAP2K5 STK17B PLSCR4 CDYL PTPRG ZNF75D NT5E AUTS2 MAN1A1 SEMA3C SH3GLB1 SCML1 GOLIM4 DACH1 TPK1 LGR5 VAV3 PERP PITX2	0.00504784	UP
MAHADEVAN_IMATINIB_RESISTANCE_DN	BCHE PTGIS CHODL CXCR4 MEOX2 HAND1 CXCL12 VCAM1 MYOC FGL2 GDF10 KIT CST1 ALDH1A2 ANO1 ABCG1 PIP5K1B CA2	0.00505583	UP
EHRLICH_ICF_SYNDROM_UP	RGS1 GUCY1A3 GUCY1B3 F13A1 PRKCH BBC3 IGF2BP3 MARK3 RARA CNN3 FHL2	0.00505765	UP
BIOCARTA_TCYTOTOXIC_PATHWAY	THY1 ITGB2 PTPRC ITGAL CD2 ICAM1 CD3D CD3E CD247 CD28 CD8A CD3G	0.00506376	UP
GROSS_HYPOXIA_VIA_ELK3_DN	CYR61 FOS EGR1 PTGS2 CTGF AKAP12 ATF3 CCL2 THBD TNC C8orf4 PRKCDBP HBEGF PPP1R15A C3 BHLHE40 TRPS1 CD93 SAMSN1 PFKFB3 S100A8 ACSL4 C10orf10 ZFP36 CACNA1H CXCL2 OAS2 IFI16 RAMP3 DUSP2 SRGN ZBTB20 IL6 CEBPB CXCL1 CDC42EP3 CD44 VWA1 PLEK DUSP4 MYC GJA1 MTHFD2 PNRC1 FGB RBPJ ETS1 MMP8 SKIL NFKBIA CSF3 TM4SF1 ATXN2L PLK2 APBA3 FST PDLIM4 ATF4 FBXO42 DMP1 KLF6 USP47 MAP3K1 SPRY2 HAX1 EPS15 ASNS SLC7A11 PTGER4 SMOX JMJD1C CXCL10 RND1 SCAF11 TIAM2 CARS KIF5A MYH9 RAD54B DZIP3 JAG1 HSPA5 PRDM2 ASCC2 EPRS AFF1 TSTA3 RABGEF1 GADD45A ANKRD1 TXNL1 ENO1 VEGFA ZNF330 TRAF6 XBP1 SIAH2 ACBD3 GSPT2 ATF1 ADM RARS IFRD1 BCL10 PDLIM5 SAT1 TGIF1 NEDD4L SLC2A1 KLF4 CXCL6 ADIPOR2 RPS6KA5 ACAP2 RCAN1 RAD23B IL13RA1 CHIC2 EDN1 FGD6 NEDD9 SLPI GBE1 ITGA6 VLDLR HIGD1A NDRG1 PRKG2 SLC20A1 NFIL3 SLC39A14 UPP1 HOXB9 LAMP2 DHRS9 ANPEP CTH EHF	0.00513937	UP
COLDREN_GEFITINIB_RESISTANCE_UP	UCHL1 MLLT11 ZEB1 MAP1B SACS TMEM158 C16orf45 JAM3 RHOQ OLFM1 DZIP1 CSGALNACT2 KCTD15 CRTAP PARVB SLC47A1 NAP1L1 ARL3 SOX12 TRAF5 CDH2 TBL1X USP36 C20orf27 CDK5RAP2 TRMT1 UBA2 WDR62 UBE2M BMS1 TIMM50 IARS DPH5 PDCD11 QPCT C10orf2 ACTR1A C10orf76 SRRT NAA10 NOL8 ALDH1B1 TUB RABEPK SLC7A1 SUPV3L1 NSMAF MDM4 POLRMT ALDH1A1 ID3 PTPRG COX15 PDHA1 PPIF IDE PPP2R1B GOT1 RFK SLC39A14 RAD50 CEBPG	0.0052266	UP
MORI_IMMATURE_B_LYMPHOCYTE_DN	E2F8 SLC16A1 HMMR PRC1 CENPA TTK NEK2 PCK2 CCNA2 MELK HMGB3 ENPEP CCNB1 DLGAP5 TOP2A DTL TXN UCK2 CHEK1 CDC20 CCNB2 MKI67 EZH2 CKS1B SMC2 PREP CDKN3 LMNB1 CDKN1A RAD51 NUSAP1 TMPO MCM2 CDK1 SMC4 ACTN4 NCAPH PRDX4 UBE2C KPNA2 PCNA HNRNPAB RRM1 H2AFX CBX1 CALM2 RRM2 LIG1 MCM7 CDCA3 XRCC6 H2AFV CKAP5 SLBP HMGB2 RBBP4 SMARCA4 TUBB4B SMARCA5 U2AF1 HMGN2 MCM10 PRIM1 HMGB1 CDC45 RAD54L MCM6 RAN DUT RAG1 STMN1 DCK MCM3 DNMT1 CCND3 IGLL1 TUBB GSN MTHFD2 ANP32E CDKN2C SLC29A1 LGALS1 TUBA1A RAMP1	0.00527135	DOWN
HOSHIDA_LIVER_CANCER_SURVIVAL_UP	TGFB1I1 FILIP1L CCL21 ANXA1 CXCR4 CCL19 IGFBP6 AEBP1 WIPF1 FBN1 COL6A3 COL4A1 SLIT3 CD48 PODXL COL16A1 TCF4 IER3 FMO1 DAB2 CTNND2 DUSP5 CHSY1 ITGA9 BCL2 EPHA4 LPP MMP7 TSC22D2 HDAC9 CPA3 LOXL2 RNASE1 TNK2 NTS NFKB2 AKAP13 IFI30 EPM2AIP1 SP100 ATP4B HMG20B SERPINB2 TEAD4 NOL7 PSMB9 FSHB AP1B1 ELOVL2 NOS2 KRT7 LPAR2 SLC7A1 TRIO SH3GL2 ACTR2 ICK IQGAP1 ABLIM1 SERPINB8 CHERP NCAPH RBM34 ADD3 EGF EMP2 GBA DDR1 GPX2 CCDC6 PRKG2 SLC12A2 ANXA3	0.00532016	UP
DAZARD_UV_RESPONSE_CLUSTER_G28	PTGS2 CTGF ATF3 CCDC85B CXCL2 IER3 H1FX CCL20 GADD45B CXCL3 PMAIP1 INSL4 TACSTD2 GADD45A CITED2 HIST1H2AI MT1G ANXA2 PHLDA2	0.00535806	UP
PAL_PRMT5_TARGETS_DN	CYR61 FABP4 MLLT11 THBD VCAM1 CNR1 TCF15 SERPINE1 KLF10 GATA4 MYT1L NUPR1 EFNB3 PVALB KRT17 METTL3 PPIE PGK2 CKB IL1A SEL1L CANX GLYR1 TOB1 GZMA LCN2	0.005406	UP
DAWSON_METHYLATED_IN_LYMPHOMA_TCL1	GAS1 ID4 EGR2 NCAM1 RUNX1T1 SLC24A3 SOX17 EPHA7 TNFAIP2 ARHGEF26 HOXD13 FOXC1 FAM184A KIAA0408 OPRD1 KLHL29 CDKN2A PRR16 FAM49B SPRY2 FOXG1 AJAP1 FOXD3 ESR1 HOXA2 SOX1 CLEC16A SOX3 HMGN1 PKP4 TNS3 CADPS2 AUTS2 PTPRD ZIC3 GOLGA5 STK39 PLCB4 TMEM30B	0.00541945	UP
REACTOME_COLLAGEN_FORMATION	COL14A1 PCOLCE2 COL21A1 COL5A2 COL15A1 COL6A3 COL4A1 COL1A1 PCOLCE COL6A2 COL1A2 COL16A1 COL4A2 COL6A1 CRTAP COL8A2 COL5A1 SERPINH1 ADAMTS2 COL7A1 COL9A3 COL3A1 COL5A3 PLOD1 COL13A1 TLL2 COL9A2 COL9A1 COL11A2 COL2A1 COL10A1 ADAMTS3 COL4A4 COL11A1 COL19A1 COL4A5 PPIB COL8A1 PLOD3 BMP1 COL4A3 TLL1 COL4A6 P4HB PLOD2 COL17A1	0.00543281	UP
ISHIDA_E2F_TARGETS	E2F8 PRC1 CCNA2 HMGB3 CCNB1 TOP2A CDC20 CCNB2 MKI67 EZH2 NDC80 SMC2 RAD51 NUSAP1 DCTPP1 ASF1B CDT1 CDK1 TYMS TK1 NCAPH AURKB PTTG1 KPNA2 RFC3 PCNA RRM1 BUB1 LBR RRM2 LIG1 MCM7 DBF4 SLBP RB1 HMGB2 DNA2 FEN1 RPA1 PRIM1 CDK2 DUT STMN1 CCNE1 TRIP13 MCM3 CDKN2C	0.00557715	DOWN
PID_AMB2_NEUTROPHILS_PATHWAY	CTGF JAM3 MMP9 JAM2 ITGAM FYN THY1 ITGB2 TLN1 LCK BLK ICAM1 SELP IL6 FGR MMP2 AGER LYN SELPLG APOB PLAU ROCK1 AKT1 LRP1 PLAUR HCK MST1 HMGB1 RAP1A RAP1B MYH2 RHOA SRC PLG NFKB1 PLAT TNF PRKCZ MST1R YES1	0.00569295	UP
CROONQUIST_IL6_DEPRIVATION_DN	GGH ABHD5 MAD2L1 HMMR CENPA TTK KIF11 CCNA2 AURKA CCNB1 OIP5 GINS1 GALE TOP2A ZWINT CHEK1 STIL CDC20 CCNB2 MKI67 FOXM1 DHFR TPX2 CKS2 SPC25 CDC6 BUB1B CKS1B SKP2 SMC2 CDKN3 PLK4 CENPE LMNB1 KIF2C CCNE2 KIAA0101 KIF22 MCM4 MCM2 CDK1 SMC4 BRCA1 TYMS TK1 KIF14 NCAPH SNRPA1 UBE2C FRZB POLE2 HMGA1 SPAG5 AURKB PTTG1 KPNA2 RFC3 PCNA SEPHS1 BUB1 FANCI TRAIP RRM2 LIG1 MCM7 DTYMK HMGB2 PLK1 HIST1H2BJ KNTC1 CDC45 WEE1 RRP12 DUT POLD1 CHAF1A STMN1 AASS NASP TRIP13 CCNF MCM3 KIFC1 APOBEC3C GMPS SBNO2 CDC25A MYBL2 RFC4 TYRO3 PTP4A3 ANP32E GALK1 FADS3 ITM2A PTPRC SPP1	0.00569488	DOWN
ELVIDGE_HIF1A_TARGETS_DN	FOS AHNAK2 SRPX IGFBP5 ENO2 PTRF CXCR4 CAV1 LOXL1 VEGFC CSRP2 OBSL1 BNIP3 S100A4 SFXN3 MAFF PFKFB3 OLFML2A FYN PAM TMEM45A WISP2 HCFC1R1 PDGFB SH2B2 NR3C1 HLA-DRB1 STC1 ANGPTL4 GJA1 IGFBP3 RBPJ NOL3 SH3GL3 ALDOC RASA4 LOXL2 ZNF292 YEATS2 UPK1A SPAG4 CYP1A1 RRAGD ATXN1 DPYSL4 KRT15 ISG20 B3GNT4 PPFIA4 WSB1 GYS1 ANKZF1 KDM4B CA9 SCNN1B BNIP3L QSOX1 ZNF395 P4HA1 CITED2 INSIG2 EFNA3 QRSL1 AK4 PDK1 GLRX ADM ANG PGK1 RNASE4 EGFR SLC2A1 LOX ILVBL MXI1 PGAP1 FAM162A FAM13A P4HA2 GBE1 VLDLR PLIN2 NDRG1 STBD1 PGM1 HK2 EGLN3 EGLN1 DSC2	0.00569749	UP
BIOCARTA_NUCLEARRS_PATHWAY	NR1H4 PPARG ABCB11 ABCB1 ABCC3 PPARA NR1H3 PPARD NR1I3 RARA CYP2E1 CYP1A2 NR0B2 ABCB4	0.00571048	DOWN
AMIT_EGF_RESPONSE_20_HELA	FOS PPP1R15A JUN SNAP25 BTG2 PRKAR1B TXNIP PILRB GADD45B ZC3H12A ROCK2	0.00578634	UP
SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2	UCHL1 TIMP3 SFRP1 IGF2 SMARCA1 CDKN1C RPRM BNIP3 NEFH LDOC1 MAGED4B BST2 CLDN5 KLK10 LHX1 IFI6 NPTX2 STAG3 BARD1 GAGE6 CDH3 GAGE7 TES CSF1 ANGPT2 CSF2 CACNA1G FOXE1 GAGE1 PAX6 WNT7A ISG20 GAGE4 MATN1 TNFRSF25 IL1R1 TP53I11 PDYN JPH3 SFN PLAT HOXA1 TNF CCNE2 CDKN1A ST14 TJP2 PLEK2	0.00580174	UP
LIU_VAV3_PROSTATE_CARCINOGENESIS_DN	CTGF NR4A2 CLU C1R RASGRP1 CREM HDAC7 PTGS1 PPT2 IFNA7 ITGB1 PSAT1 HSPA5 GAD2 TH	0.00594452	UP
REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM	GPD2 UGT1A9 HMGCS2 PPARG ACOX1 HMGCR CPT2 BDH1 PCCA PPARGC1A AGT PRKAB2 PCCB ARNTL HADH ELOVL6 ACADS SLC25A1 ALAS1 AGPAT5 PEX11A HMGCS1 NPAS2 ACADM ACAT1 DECR1 TBL1XR1 ECI1 GK HMGCL ACSL5 LPCAT4 SLC25A20 DGAT1 PLIN2 MUT HADHA FABP1 CDK8 AGPAT2 MED14 ECHS1 GPD1L ELOVL1 CPT1A TNFRSF21 MED20 PPARA ME1 YAP1 HADHB FDFT1 NCOA2 TXNRD1 LPIN2 ESRRA MED23 HSD17B12 NCOA6 CCNC MED21 FHL2 TECR AGPAT3 PRKAG2 SREBF2 MED17 CDK19 NCOR1 RXRA MED7 ACSL3 MED6 EP300 MED9 MED4 MED18 MED24 MED31 APOA2 ANKRD1 MED8 ACADVL MED25 HDAC3 ACSL1 CPT1B FASN CLOCK NFYA TIAM2 ELOVL2 ACACA MED12 TEAD4 ACLY TGS1 NCOA3 MED16 CYP4A11 SREBF1 MED13L SULT2A1 CREBBP AGPAT1 NR1D1 MED27 NRF1 MED15 CD36 TEAD1 CYP7A1 ABCA1 ACADL CYP1A1 NCOA1 MED1 ACSL6 MED22 APOA1 TRIB3 NCOR2 GPD1 SIN3B OXCT1 ACACB RORA NFYB LPIN1 TEAD3 AGPAT4 PRKAA2 ANGPTL4 TBL1X ABCB4 GLIPR1 FADS1 ELOVL4 ACSL4 ELOVL5 LPCAT1 G0S2 SMARCD3 WWTR1 CTGF	0.00597169	DOWN
AFFAR_YY1_TARGETS_UP	FOS NAP1L3 UCHL1 CRYAB BEX1 CLU FXYD6 ID4 CHODL MYH11 PDLIM3 SYT11 CFH CDKN1C EFEMP1 DUSP1 MAL CDO1 PLTP LDB3 PPP1R15A LAMB2 MS4A1 TGM2 EPHA7 SNURF ACTC1 MYOM1 CPEB1 BTG2 ALCAM MAPK10 TPD52L1 DMPK NGFR NNAT ATP6V0E2 SLC27A3 ICAM1 RAMP2 CTSF SLC2A3 DSTYK EPHA2 TPH1 ABCA3 CTNND2 SH2D1A NTF3 EBF2 PIP4K2B MMP2 NPTX2 ITGA9 HSF2 HOXA4 PTP4A3 FJX1 LPIN1 GPC3 TPM1 BDNF RNF41 TCFL5 SLC12A5 FYB PRKAR1B EHD1 CEND1 USP20 LDHB TGFB2 SERPINB4 WT1 SIM1 SOX2 FABP3 MYH3 FXYD2 SPOCK3 TLE4 MPG LRP2 TTLL1 MYCN KDR TSSK2 NEUROD6 COL10A1 FLT1 TXNIP SLC9A3R2 TBX2 KIF17 KLK8 MYLPF MYL1 ABCA1 CBLN1 ARR3 GBP1 MYH7 ABCC5 JAK3 SLC1A6 RPGRIP1 COL19A1 S1PR5 DRD4 BLCAP KIF5B SLC6A14 MYO1C RORC TNNC1 NID2 RBMX HSD17B1 MYH6 MDM2 GRIA3 PMAIP1 MPP6 UBC TINAGL1 ELOVL2 BMP4 STK25 TSC22D1 MYH2 TNNI1 BMP6 RND3 ADAM15 MYH1 BCL2L1 PDGFA ABCD4 SLC2A4 PROX1 ANKRD1 GADD45G ZNF264 TNFRSF10B SRC SFN GFER EFNA3 TAP1 TNNC2 HIST2H2AA3 SURF1 WNT16 NDUFA7 PAWR CD55 B4GALT4 EGFR CDKN1A FAS PEX19 PFKFB2 BAK1 PSRC1 LGALS9 PMM1 DCXR PAFAH2 ZNF3 KRT19 CFTR PLOD2 PLCB4 STX3 HIST1H1C ABAT SPAG1 CASP7 PERP ACOX1 HIST1H2BC ITGB6 EHF	0.00602287	UP
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN	SLC38A4 CYP2B6 EHHADH CTH ETFDH NAT2 SULT1B1 CYP4F2 ABCB11 ADH6 OASL CPT2 SRD5A1 OTC CYP4F11 CYP2J2 CYP4F3 PCK1 CYP2C9 ABAT TST CDC14B HADH AKR7A3 RUNDC3B SELENBP1 DHTKD1 TTPA ALAS1 FMO4 MYO1B SLC46A3 ADH1A GNE ALDH6A1 DCXR NUDT6 CES2 POR GPT MLYCD BTD ALDH3A2 ALDH1L1 ALDH5A1 CAT NR1I2 GYS2 PNPO DHRS1 CYP3A43 SCP2 RWDD3 CYP27A1 BLOC1S1 DAO GCDH F12 KNG1 TAT PLG MTHFD1 AADAC CIDEB EPHX1 ACYP2 SYBU AQP9 HAGH CYP2C8 SERPINC1 SLC10A1 C8A LECT2 GRHPR NR1I3 PFKFB1 ECHDC2 MAT1A ANGPTL3 GPLD1 ACBD4 AZGP1 CPB2 AFM PDK4 HNF4A RORC CYP4A11 CLDN14 BHMT RCL1 SULT2A1 HAAO NECAB2 GLYAT BAAT ECHDC3 HPD ACADL AASS MYRIP MTTP CCL16 SLC22A1 CUX2 CYP1A2 SEC14L2 FMO3 MASP2 SLC38A3 CA5A ETNK2 RDH16 KLF9 SERPINA10 HAO1 AGXT SLC2A2 ITIH1 AR ABCA6 NUDT7 C6 TFR2 CCL14 GAMT OGDHL PIPOX ABCB4 AOX1 ACSM5 ST3GAL6 HSD11B1 COL18A1 RGN BHMT2 SLC16A2 ABCA8 ADRB2 KCNJ8 F8 CDO1 SORBS2 MPDZ SERPING1 ECM2 RHOB HSD17B6	0.00603255	DOWN
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN	FAM129A SRPX CLU SOBP S100B HTRA1 KLF2 GPNMB KCNMA1 DFNA5 ADAM19 ST8SIA1 NRP1 MMP9 PRNP COLEC12 BCL6 RHOH GJA4 JUN ITGAM FCGR2B S100A8 ENTPD1 TDO2 C1QA DOCK4 ITM2A RPS6KA2 HLA-DQA1 MRC1 C5AR1 NCF2 TSPAN2 ST6GALNAC5 CREB5 IL7R TRAT1 SLC16A7 HSD11B1 TM6SF1 FCN1 LCP2 C1QB DAB2 PPBP CXCL1 CD163 CYBB MARCH1 CLEC7A CR1 FPR1 STAC PLA2G7 SLC16A6 TGFBI MAF P2RY10 FAM198B PADI4 ETS1 S100A9 CST1 SGK1 FYB ALOX5 CEBPE MS4A2 UTS2 SLAMF8 RNASE1 NEK1 ATP10D MARCO CD14 NKTR HRH4 LFNG IL3RA AKAP13 CD1E S100A12 CST7 GLUL F5 CD1A MMP14 IL10 CHI3L1 SLC28A3 TEX15 CYTL1 DEFA4 FCGR2C SRSF6 SLC7A7 BPI SRSF4 CCL23 CLEC5A RAB30 ANTXR1 CXCL3 HK3 SLC11A1 PCSK5 SLCO2B1 PTCD1 MMP12 RAP1A PDK4 FOLR3 ENC1 PAX2 IL5RA CTSB RAP2A TCERG1 KRT86 FPR3 IFNGR1 ADORA3 CLEC4A CDH8 HTR2C CXCL5 CAMK1D EPAS1 ZMYM2 S100P FCAR CUX1 OR7E24 HIPK1 LGMN NDRG2 AMFR RAPGEF2 CDC42 NPL DNAJC3 TSPAN15 CEACAM8 ALDH2 CD9 ME1 ADAM9 PLBD1 CD24 CEACAM6 SLPI PID1 SERPINA1 SERPINB1 DACH1 MMP1 PADI2 TMEM33 EMP1 IL1R2 CORO2A ETNK1	0.00604739	UP
MIKKELSEN_IPS_ICP_WITH_H3K4ME3_AND_H327ME3	CNN1 GUCY1A3 CHODL MEIS1 TPPP3 ITIH5 ISLR SOX17 PAMR1 FXYD5 LAMA4 PCDHGA1 TGFB3 KCNAB1 CALY TLR5 CHST3 CRABP2 CXCL1 PTN CD44 FGL2 PTGS1 CDKN2C LYL1 VAV1 KCND2 COL7A1 CIITA ETV2 NOL3 PHYHIP TGM1 NPY2R PDZD7 EXTL1 SNCA LTA ADARB2 CA14 TEKT2 MC4R LECT1 KCNJ5 ALOX15B COL4A4 OPCML UCP1 TNFRSF8 MST1 ESR2 HOXB13 CRYAA PDE11A DKK1 GRM3 KLHL1 PDYN GNAT1 KLHL5 SPINK2 CACNB3 TRIM46 COL4A3 PTH2R TRIM15 KCNK10 SLC2A10 SCNN1A MST1R EDN2 ABCC3 BEST2 KCNJ2 PTPRR	0.0061648	UP
WILCOX_RESPONSE_TO_PROGESTERONE_DN	MGP MYL9 DES IGFBP5 COX7A1 FN1 ATP2B4 COL5A2 CSTA PDLIM7 NEFH COL1A1 SPON2 COL1A2 PECAM1 PCDHGA1 COL16A1 NTM CLIC4 COL6A1 COL8A2 KCNK3 PIEZO1 CCND1 MMP2 MME INHBA L1CAM IGFBP3 BDNF IGLL1 STAR FRMD4A LOXL2 PLAU PCDHGA3 PRRC2A OXTR CUX2 CATSPERB DST OGT CHRNE COL11A1 PLEC HIPK2 METAP2 NOTCH2NL ARHGDIA PDE12 NOX3 TRA2A MYH1 IGF1R THBS1 MICAL2 TNFSF10 IGFBP2 AKAP9 HSD11B2 ABCC6 CPM CYP2C18	0.00623511	UP
TING_SILENCED_BY_DICER	CYR61 RTN1 LHFP CXCR4 RFTN1 C10orf10 HOXB2 SPARC VIM RASGRP1 APOBEC3G SFRP4 ZNF550 TM4SF1 DHRS2 DKK4 LIPG PELI2 SERPINA1 PANK3 SLC4A4	0.00625874	UP
WENG_POR_TARGETS_LIVER_UP	CYP2B6 CYP2C18 AQP8 GSTA2 ETHE1 CYP51A1 DHCR24 ENTPD5 UGDH HMOX1 HMGCS1 SCD PGD CYB5B TMEM97 MSMO1 CLDN3 IDI1 FDPS TMEM176A GSTM1 ACTG1 LGALSL SQLE GSTM2 CSAD GADD45B ASNS CD36 SLCO1A2 CYP7A1 CYP2A6 GSTM3 CYP26A1 ANXA5 LGALS1 PRNP LPL	0.00628458	DOWN
BILANGES_SERUM_SENSITIVE_VIA_TSC2	CYR61 CTGF THBS2 TUBB2B COL1A2 NEDD4 TBC1D16 COL3A1 NPM3 GON4L HIST1H1E KIFC1 C7orf26 SMG6 CCDC88A EIF5B CRIM1 DICER1 ANKRD26 GLG1 NUMA1 SMARCA4 EIF3C UBA6 EIF3A GBF1 BPTF SNRPD3 SPAG5 DDX46 ATP1A1 THOC2 KIF1B	0.00630198	UP
NABA_COLLAGENS	COL14A1 COL21A1 COL5A2 COL15A1 COL6A3 COL4A1 COL1A1 COL6A2 COL1A2 COL16A1 COL4A2 COL6A1 COL18A1 COL8A2 COL5A1 COL7A1 COL9A3 COL3A1 COL5A3 COL13A1 COL9A2 COL9A1 COL11A2 COL2A1 COL10A1 COL4A4 COL11A1 COL19A1 COL4A5 COL8A1 COL4A3 COL4A6 COL17A1	0.00639094	UP
GAJATE_RESPONSE_TO_TRABECTEDIN_UP	FOS ATF3 CLU DDR2 MYH10 RGS2 ANXA1 CXCR4 CFD CSRP2 TUBA1A GPNMB SEPT6 S100A4 C1R CPE OLFML2A IGFBP7 CLIC4 PROS1 SRGN IL6 CD44 TAF15 DUSP5 TNFAIP3 GSN TGFBI TM4SF1 NUCB2 ISG15 NUPR1 GOLGA8A TXNIP CASP4 GSTA4 GARS ASNS NID2 FOLR1 CYP19A1 UGCG CARS S100P FGG CASP9 HLA-C GADD45A EML2 KLRC3 CRIP1 TRAPPC6A CCNG2 CDKN1A ARL6IP1 NNT MSMO1 VLDLR CBS ANXA4 C4BPA PCK2 PHYH CLDN7 OASL IL18	0.00640733	UP
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP	PROM1 IMPA2 SLC35A3 PCK1 TDGF1 ABCD3 HADH PIP5K1B CDH1 CFTR HRH1 SLC35D1 MPST ACVR1B GPX2 CTSA GOLGA4 CD24 CYB5B DDR1 PDXDC1 ATP1A1 FCGRT MRPL12 REG1B PRKCD DNAJC7 PPID IDH3G PYGB NDUFB5 VAMP7 ZBED1 PPP2R5A SEL1L3 NDUFS6 USP10 COASY IVNS1ABP SURF1 ARF4 DHX15 AHCYL1 SREK1 NFKB1 CNOT1 WDR1 CBLB UBE4B ATP5I CSNK1D RRM1 HIPK1 PRKAG1 MGRN1 RERE PDHB SARS B2M CUL4B DDB1 LAMP1 BTN3A1 TMEM115 POLR2K XRCC5 MFSD10 SON RPL36A TCF25 EEF1A1 RAP1A TRIM44 RBL2 RPS13 TPR DRG1 RPS27 HMGN4 RPL13 TNRC6B MANF C9orf16 LYRM1 DDX27 RPL38 TRIM33 LAGE3 SUMO4 GAS6 TMEM63A PHLDB1 USP4 NUDC MRFAP1L1 KDR CYP2A13 CHIT1 AARS DUSP3 C2 TERF2IP CD44 GNAI2	0.0064617	DOWN
REACTOME_PACKAGING_OF_TELOMERE_ENDS	HIST1H2BC HIST1H4H HIST1H2AE HIST1H2BH HIST1H2AC HIST1H2BD HIST1H2BG HIST1H2BE HIST1H2BI HIST1H2BF HIST1H2AJ HIST1H2BM HIST1H4K HIST1H4B HIST1H2BK HIST1H4J HIST1H4D HIST1H2AD HIST2H2AA3 HIST1H4F H2AFX HIST1H4C HIST1H2BO HIST1H4L TERF2 HIST2H4A HIST1H4A HIST2H2BE HIST1H2BB TERF1 HIST1H2BJ H2AFZ HIST1H4E HIST1H4I HIST1H2AB TINF2 POT1 HIST3H3 HIST1H2BN HIST1H2BL ACD TERF2IP	0.00646454	DOWN
PLASARI_TGFB1_TARGETS_10HR_UP	PTGS2 CTGF CNN1 GUCY1B3 TIMP3 GREM2 FXYD6 TNC EGR2 THBS4 HBEGF PPP1R15A ITGA5 BHLHE40 MCAM ELN DUSP14 MEOX1 MMP9 TGFB1 EREG CRISPLD2 GFPT2 HTR2B MAFF NUAK1 STMN4 JUNB PLK3 CSPG4 CHST11 FGF2 CX3CL1 HSPA2 CDH6 NES GATM RGS16 TSPAN2 FSTL3 PDGFB NFATC1 IER3 COL8A2 IL6 ALDH1A3 IER2 DUSP6 SNAI1 PTHLH DUSP4 CD40 PMEPA1 DUSP5 PDGFC TNFAIP3 CCL20 SERPINE1 KHDRBS3 NGF INHBA CCL17 TNNT2 TNFRSF12A FJX1 FKBP5 ACTA1 TTC9 FGF18 SPHK1 ARC LRP8 WNT11 CA6 RASL11B TFPI2 CREB3L2 ALDH1A2 KLHL29 FOSL1 ARG1 LAS1L CMKLR1 RBFOX1 FOXC2 GFOD1 CXCR6 IL11 FLT1 LRRFIP1 OLR1 HEYL SEMA7A GJB3 PLAUR KLHDC8A HCK HIVEP3 TGFBR1 HIP1R PKP1 PLEKHG3 GADD45B GJA3 IL1RL1 ADAM12 PTK2B ITGB3 HEY1 PVR ALS2CL LIF PMAIP1 FGF21 NPPB JAG1 PRG4 ELAVL2 UBE2G2 SERP1 PPP1R13L UNC5B CRY1 PDGFA CXCL14 GMPPB ANKRD1 SFN PRKAR2A NEBL HAS2 VEGFA RUNX1 LMO1 SIAH2 ASS1 IVNS1ABP SOCS2 STK38L PDE4DIP MICAL2 CARD10 SLC2A1 MGLL TNFRSF11B RNF19B FLNB ENDOD1 ENTPD7 GCH1 ANKH KLF13 RAP1GAP2 PRKG2 NUDT6 GCNT2 ABCB1 SLC20A1 NUAK2 NFIL3 PAPSS2 KCNK1 HK2 ARNTL ENPP1 CNNM4 F2RL1 MYO1D GALNT3 CTH	0.00651168	UP
REACTOME_ORC1_REMOVAL_FROM_CHROMATIN	CCNA2 ORC2 PSMC6 CDC6 PSMB8 CDKN1A ORC5 ORC4 PSMD3 PSMA5 PSMD7 MCM4 PSMD13 PSMB10 CDT1 PSMD10 ORC1 MCM2 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 CCNA1 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 ORC6 PSME4 PSMD14 PSMB6 MCM7 PSME2 CDKN1B PSMD12 PSMB1 PSMD6 PSME1 RB1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 ORC3 CDK2 MCM6 RPS27A MCM5 UBA52 MCM3	0.00652999	DOWN
KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM	CMAS FPGT GFPT1 GMDS UGDH HK2 GALK2 GALE PGM1 MPI GNE PMM1 UGP2 NANS UAP1 HEXB GMPPA NPL GPI PGM3 PMM2 GMPPB HEXA TSTA3 AMDHD2 GALT CHIA HK3 UXS1 GNPDA1 NAGK HK1 RENBP GCK CHIT1 CYB5R3 CYB5R1 GALK1 GFPT2	0.00653349	DOWN
NIELSEN_GIST_AND_SYNOVIAL_SARCOMA_UP	BCHE PEG3 BEX1 SFRP1 CDKN1C APLP1 CA11 TOX PCDHA10 KIT ALDH1A2 PLCB2 COL4A5 BMP4 DLK1 ITM2C EDN3	0.00660566	UP
KANG_DOXORUBICIN_RESISTANCE_UP	PBK ASPM NQO1 MAD2L1 HMMR PRC1 CENPA KIF4A AURKA OIP5 GINS1 TOP2A ZWINT CDC20 RAD51AP1 MKI67 FOXM1 TPX2 CDC6 BUB1B CDKN3 PLK4 LMNB1 NUSAP1 ASF1B KIAA0101 MCM4 CDCA8 CDK1 TYMS WHSC1 TK1 NCAPG BIRC5 NCAPG2 HJURP CENPM RRM1 POLQ BUB1 FANCI RRM2 DTYMK HMGB2 PLK1 ATAD2 DSCC1 ABCC1 RFC4 POLA2 BARD1 FOSB	0.00665874	DOWN
REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE	MAD2L1 CCNA2 AURKA CCNB1 CDC20 PSMC6 BUB1B SKP2 FBXO5 PSMB8 PSMD3 PSMA5 CDC23 PSMD7 PSMD13 PSMB10 PSMD10 CDK1 PSMD11 PSMA3 UBE2D1 PSMC4 PSMD8 PSMA6 UBE2C PSMF1 AURKB PTTG1 PSMD5 PSMB3 UBE2E1 PSMA1 PSMA4 PSMD9 CCNA1 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 SKP1 BUB3 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PLK1 CDC27 ANAPC5 PSMB4 PSMB9 ANAPC1 PSMB2 CDC16 PSMC2 PSMC5 PSMD4 PSMC1 CDK2 RPS27A UBA52 CDC14A BTRC CUL1 ANAPC10 ANAPC2	0.00669088	DOWN
MANTOVANI_NFKB_TARGETS_UP	CCL2 CXCL12 SPP1 C3 VCAM1 SLC16A4 CP IGFBP7 SLC29A1 C1S ATP8A2 OSMR INHBB STEAP4 DUSP6 CXCL1 MYC BCL2 FSD1 SYN3 ZCWPW1 FLT1 CASP4 TRPV6 IL10 CXCL9 GTF3C1 PRKCE CCL7 VEGFA MTRF1 TRIM2 CDC14B CA2	0.00678014	UP
PID_CXCR4_PATHWAY	RGS1 RHOB ITGA7 CXCR4 CXCL12 ITGA5 PLCB1 MMP9 ITGA1 DNM1 FYN PTPRC STAT5B LCK INPP5D BLK PIK3CD ITGA4 HLA-DRA GNAI2 GNAZ CD4 HLA-DRB1 CD3D FGR CD3E GNAO1 PIK3CG VAV1 CD247 ITGA9 PTPN6 ARRB2 STAT5A PIK3R3 LYN PIK3CA PLCB2 LIMK1 FOXO1 PTPN11 GRK6 STAT2 AKT1 PIK3R1 HCK ARR3 SSH1 ITGA8 ITGA10 MAPKAP1 PIK3R5 MTOR ITGB1 PTK2B CSK GNB1 STAT3 PIK3R2 PTK2 PDPK1 PLCB3 JAK2 STAT1 RAP1B CD3G ITGA3 HGS RHOA VPS4A ITGAV PXN SRC CFL1 MLST8 PTEN GNAI3 RAC1 BAD CDC42 CRK PRKCZ RALB VPS4B PIK3CB ITGA6 YES1 ITCH ITGA2 PAK1 GNAI1 GNA13	0.00691153	UP
BASSO_CD40_SIGNALING_DN	LMO3 KCNN3 RUNX1T1 TRIB2 IGFBP6 DFNA5 IRS1 BCL6 CNR1 VNN2 BTG2 ARL4C POU2AF1 CSF2RB PRKAR2B LTB CD27 PNOC NCF4 SH2B2 RASGRP2 BICD2 ST3GAL6 AIF1 BMP7 NINJ1 TTC9 GRAP ITGB7 CAMP HDAC9 ORAI2 TUBB3 AQP3 TCF3 PTPN22 NPAS1 RIMS3 ISG20 ST6GAL1 CD38 RNF187 PTPN18 RERE PTP4A2 UBE2J1 SYK RAPGEF5 ID1 SLC2A5 CRYZ CTDSP2 BIK RAPGEF2 METTL7A ARHGEF18 ID3 BLNK HSD17B8 ALDH5A1 TSPO GCNT1 CDH17	0.00691965	UP
YAMASHITA_METHYLATED_IN_PROSTATE_CANCER	TAGLN IGFBP5 TFPI GPNMB SPP1 AEBP1 G0S2 DPEP2 COL1A1 S100A8 SPARC HSPA2 TRPV2 PRAF2 NNAT DYSF CALCB SERPINE1 PTGES FCER2 MMP7 TM4SF1 OCM2 SLC6A2 MYOD1 S100A5 CLDN6 CYP1A1 KLK6 KLK8 GAS6 MMP13 S100G CLDN18 SLC34A2 SCGB1A1 MMP10 ADH7 CCL7 RGS17 ANKRD1 OPTN GYS2 HEPH PLAC8 CCDC68 AQP8	0.00699842	UP
YU_MYC_TARGETS_UP	ASPM ECT2 E2F8 GMNN AURKA CCNB1 TOP2A DTL TXN KIF20A CCNB2 MKI67 CKS2 UCHL5 CKS1B IDI1 CDKN3 DCTPP1 FDPS RACGAP1 KIAA0101 CDK1 TFDP1 STRAP BIRC5 BRCA2 KPNA2 PCNA RRM1 BUB1 NUP54 HMGB2 PLK1 UBE2S CLIC4 TSPAN4 DFNA5	0.00710109	DOWN
KEGG_STEROID_BIOSYNTHESIS	SOAT1 CYP51A1 DHCR24 CEL EBP MSMO1 LSS FDFT1 NSDHL DHCR7 TM7SF2 SQLE SOAT2 CYP27B1 HSD17B7 LIPA	0.00716388	DOWN
BROWNE_HCMV_INFECTION_1HR_UP	HLF IGFBP5 NR4A1 PCDH7 ATP2B4 CXCL2 RASGRP1 CD4 IL6 GPR18 PCBP4 RET VAT1 CXCL1 PMP2 FUT9 ATP2B2 TBX5 GRK1 IL6ST LDLR SOX5 SLC6A1 PRKCA CLGN KLHL23 SEMA3D TLL2 BFSP2 WIZ HTR7 PTPN11 BRD3 IL24 MMP14 AGTPBP1 ZBTB22 GRIA1 AFF2 FSCN2 CHST1 MAZ PPP1R13B MT4 ONECUT1 NDST1 POU1F1 IGF1R UBE2B BCL2L11 DEFA6 MBTPS2 MFAP3 FGFR3 GSS TFRC	0.00724651	UP
ROSS_AML_WITH_CBFB_MYH11_FUSION	MYH11 MN1 NRP1 IL10RA CD1C S100A8 GIMAP4 SPARC KCTD12 PTPRM TNFAIP2 CD52 CEBPD CFP NACC2 DUSP6 CBFB MDFIC CCR2 AK5 CLEC10A CYBB LPAR1 CLEC7A TGFBI S100A9 FYB MEGF9 TES CD1E KIF17 HPCAL1 CHI3L1 SLC7A7 MEF2A QPCT CLEC4A GRHPR ST18 LGALS2 PLXNB2 SLC38A1 TNFSF13 NAGA DYNLT1 ANXA11 IL13RA1 PLBD1 CTSS MTMR11 PGM1	0.00725036	UP
BIOCARTA_BCR_PATHWAY	FOS CD79B JUN CD79A BTK NFATC1 PRKCB NFATC4 PPP3CC VAV1 PLCG1 PRKCA LYN PPP3CB NFATC3 MAP3K1 ELK1 HRAS MAPK8 SHC1 CALM1 RAF1 MAP2K1 GRB2 CALM3 CALM2 PPP3CA SYK RAC1 MAPK3 MAPK14 SOS1 BLNK	0.00735291	UP
KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	MYL9 KCNMB1 ACTG2 GUCY1A3 GUCY1B3 AGTR1 MYH11 EDNRA ACTA2 ITPR1 RAMP1 CALD1 KCNMA1 PPP1R12B PLCB1 PLA2G5 MYLK RAMP3 PRKCH ADCY2 PRKCB RAMP2 CACNA1C ADCY7 KCNMB4 NPR2 ADRA1B PRKCQ PLA2G2D MYL6B GNA12 ADORA2A NPR1 PPP1R12A PRKACG PRKCA ITPR2 KCNMB3 PRKCG ARHGEF1 CALML5 ADCY3 JMJD7-PLA2G4B PLCB2 PRKG1 CALCRL PLA2G4A ADCY8 PRKACA PTGIR ROCK1 PLA2G2E CALML3 ADRA1D CACNA1D GNAS PLA2G6 PLA2G3 ADRA1A KCNMB2 CYP4A11 PRKCE ADCY1 PLA2G1B AVPR1B CALM1 PLCB3 MYL6 AVPR1A GUCY1A2 RAF1 MAP2K1 PLA2G2F CACNA1S BRAF CALM3 CALM2 RHOA PLA2G2A MYLK3 CACNA1F GNAQ ARAF PPP1CC PPP1CB MAP2K2 ARHGEF11 MAPK3 ROCK2 ARHGEF12 PPP1CA PRKX ADCY9 PRKACB ITPR3 PRKCD GNA11 PLA2G12A MAPK1 ADCY6 PLCB4 PLA2G10 GNA13 ADORA2B	0.00742007	UP
WESTON_VEGFA_TARGETS_6HR	MGP GEM CCL2 NNMT SGCE RHOB ELN CFHR1 GJA4 VCAM1 COL6A3 HTR2B ISL1 RGS5 ROR2 THY1 COL1A2 VIM C1S COL6A1 BGN FAP FHL3 COL5A1 MMP2 ART4 IGFBP3 BDNF TFPI2 GSTT1 PVALB OXTR SHC3 VCAN ESR1 NID2 SLC6A8 BMP4 CCL7 BCKDHA ANKRD1 SDC4 SULT1E1 SP3 SAT1 AQP7 UNG PRKAB1 TNFSF10 SEMA5A FBP1 KRT18 POSTN MEST FGFBP1 F2RL1 ADORA2B	0.00742311	UP
BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_UP	CYR61 PEG10 SGCE HTRA1 SEMA3A LMO2 IGF1 HSPA6 CDH11 TPM1 MDK ENC1 MYOF ARSF ID2 FBXO21 SHOX2 MT2A MT1X RABGAP1L PPP2R1B PRSS12 CA2	0.00747071	UP
PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP	GRAMD1C FNBP1L XK HOXA9 TMEM30B SLC35A3 E2F8 KIF15 CALML4 RFC5 ERMP1 NEK2 CXADR MYO5C HMGB3 NEK4 KRT19 GINS1 DTL PPM1A RAD51AP1 MIS18A ATAD2B KCTD3 CASK GCH1 FANCL ELF3 EZH2 HOXA10 OSBPL11 UPF3B MECOM CENPF HELLS ABCA5 EYA2 CDC7 NUP62CL RMI1 FDFT1 ENOSF1 ARHGAP5 PRPS2 LMNB1 TMPO CDKN2B FMR1 BRWD1 SCML1 CCNE2 KDM6A UBXN7 TOPBP1 B4GALT4 MRPL39 SYNJ1 OPA1 PRKX PIGA CDK1 INTS7 SMC4 USP25 WDHD1 GSPT1 SNRPA1 PLSCR4 SS18L1 BCL2L11 NDUFB4 REV1 GART C11orf80 STAG1 ETS2 MTF2 CCHCR1 ZXDC PRPF39 BAG5 POLA1 AHCTF1 MCPH1 POLD3 CDC42BPA U2SURP ZFX ATP8B1 CASP8AP2 DDX3X RBBP4 ATAD2 BRIP1 KLHL2 KNTC1 PMAIP1 CHML PARD6B SPICE1 FAM50A ESR1 CREBZF ZNF236 DR1 STS HOXB3 DONSON SYCP2 NASP CDKN2A MCM3 CEP152 CCNL1 RBL1 HLTF GOLGA8A CENPI DIP2A RBM15 NR1D2 CENPJ MSL2 HOXD10 BARD1 WDR76 NUP210 ANKLE2 ZRSR2 ANKRD36 PSIP1 ZNF532 PER3 BHLHE40 MEIS1 NR4A2	0.00757431	DOWN
VANHARANTA_UTERINE_FIBROID_UP	HSD17B6 GPM6B PLP1 SULF1 EDNRA FN1 TRPS1 COL5A2 PDE8B COL4A1 HTR2B COL1A1 COL4A2 TFAP2C PRKCB LTBP2 CCND1 CRMP1 ART4 TMSB15A COL3A1 NAV2 ZMAT3 LOXL2 MFAP2 STARD13 DDB2 COL9A2 SPCS3 MMP11 ERCC3 HRASLS ZFYVE9 TGOLN2 TYMS FDXR UBR2 ITM2C SOX4 EFNB2 HEPH IGSF3 MEST SATB2	0.00770672	UP
BIOCARTA_COMP_PATHWAY	C7 CFD C3 C1R C1QA C1S C5 C1QB C4A C6 C2 MASP1 MASP2 C9 MBL2 C8A CFB	0.00776877	UP
AMIT_DELAYED_EARLY_GENES	ATF3 RBMS1 BHLHE40 MAFF JUNB ZFP36 BTG2 CREM NAB2 ZFP36L1 KLF10 FOSL1 ZFP36L2 KLF6 PIAS1 ID1 FOSL2 HES1	0.00788676	UP
SANDERSON_PPARA_TARGETS	EHHADH ETFDH HMGCS2 CPT2 ACADM DECR1 ACOT8 ECI1 ALDH3A2 HSD17B4 DECR2 CPT1B FGF21 CD36 G0S2	0.0079254	DOWN
BASSO_HAIRY_CELL_LEUKEMIA_DN	SYT1 MFAP5 DLC1 ANXA1 WWTR1 C16orf45 PCDH9 HBB SUSD5 GAS7 SDC3 FGFR1 KCTD12 PTPRM FGF2 TIMP1 CAMTA1 PLXNC1 MAPK10 ENG DAPK1 CPVL NOVA1 RTN2 RRAS CCND1 TACC1 SCN1B RECK DPYD AIF1 SLITRK5 MAF LILRB2 IGFBP3 ARRB2 FLT3 CYB5R1 TIMP4 TBKBP1 S100A13 RAB13 PHF2 IL3RA EPB41L2 DST SPRY2 CTBP2 SIX3 IL1R1 ACTB MYF6 MTSS1 RCBTB2 RPLP1 TNFRSF1A MYOF B2M GABARAPL2 CD63 VAMP3 PRSS23 PTTG1IP ME3 THBS1 RNF11 ARAP2 PDE4DIP TCF7L2 TMEM59 RIN2 PPIC ADCY9 TRIM2 PLOD2 SMPDL3A EMP1 IL1R2 HPGDS IL18	0.00803214	UP
MATZUK_CENTRAL_FOR_FEMALE_FERTILITY	EGR1 DDR2 CDKN1C LEPR TGFB1 CPE GHR NPR2 INSL3 LEP PROP1 AIRE LHB CGA KISS1 CDK4 CRTC1 TSHB STAT3 AFP FSHB POU1F1 GGT1 GNRHR GNRH1 TKT ACVR2A	0.00803983	UP
BAUS_TFF2_TARGETS_DN	BAG2 PCP4 TIMP3 RBP4 BEX4 DDX6 ART3 HEBP1 CTSC PRDX2	0.00804127	UP
MCCLUNG_DELTA_FOSB_TARGETS_2WK	CTGF FHOD3 INA NEFM CDK14 STMN2 SERPINI1 COL5A2 TUBB2A OLFM1 NEFH ADARB1 ASAP1 NPTX1 NOV APBA2 MEF2C BDNF MOBP SEPT9 STMN1 CADPS GARS ADCYAP1 CCK SCN1A SYT2 TBR1 GSTO1 ELAVL2 TPBG NMBR PTPRK CLN8 FHL2 INPP5J SMAD1 VSNL1 IMPACT MGST3 TXN HMGCS1 HSPA1B	0.0081973	UP
BROWNE_HCMV_INFECTION_30MIN_UP	FOS EGR3 EGR2 RHOB DUSP1 GPX3 CTNNA2 JUNB COL6A2 ZFP36 PLXDC1 ASPA COL6A1 SOCS3 APBA2 TFEC C1orf61 SIX6 EYA4 PTK7 ST8SIA3 RGS6 NFATC3 COL2A1 TRADD KRT37 POT1 AJAP1 CD38 PTK2B CAV3 ALB CAMK2G PDYN DCTN5 GC KITLG ZER1 HSF2BP TSFM SMARCD2 APOM THBS1 C4BPB LCN2 FAM13A CASK ADH1A IFI27 IL10RB	0.00825994	UP
CHIBA_RESPONSE_TO_TSA	CYR61 CTGF CLU RHOB DUSP1 TGM2 IFITM3 PNRC1 DHRS2 H3F3B BSCL2 JMJD1C PRPF3 ANAPC13 TPP1 ID2 LYPLA2 STAT1 RRM2 CDK11A SQSTM1 RHOA ATP6AP2 PRKRA PRDX1 GRN TPI1 H1F0 NIPSNAP1 DNAJB1 SDC4 STX6 OPTN ID3 TXNRD1 CDKN1A HADHB BSG CYP4F2	0.00828225	UP
SUZUKI_RESPONSE_TO_TSA_AND_DECITABINE_1A	PTGS2 TIMP3 SFRP1 COL6A3 SNRPN PTPRM LAMA2 KYNU FAM127A CYP4B1 PCDH8 TIMP2 FOLH1 DNASE1L3 ANGPT2 SEZ6L CDKN2A XCL1 S100A10 LAMA3	0.00833872	UP
SCHRAETS_MLL_TARGETS_DN	GAS1 MGP GREM1 THBS2 HSPB8 THBD CD93 COL6A3 COL6A2 ARHGDIB COL6A1 CD53 CTSH TGFBI HOXC8 ENPP2 FOXC2 LIMK1 SPRR1A GSTA4 IL1RN CDKN1B DFFB CAP1 HNF1B MGLL ACADM AGT GATA6 PITX2	0.00835348	UP
REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS	MAD2L1 CCNB1 CDC20 PSMC6 BUB1B PSMB8 PSMD3 PSMA5 CDC23 PSMD7 PSMD13 PSMB10 PSMD10 CDK1 PSMD11 PSMA3 UBE2D1 PSMC4 PSMD8 PSMA6 UBE2C PSMF1 PTTG1 PSMD5 PSMB3 UBE2E1 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 BUB3 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 CDC27 ANAPC5 PSMB4 PSMB9 ANAPC1 PSMB2 CDC16 PSMC2 PSMC5 PSMD4 PSMC1 RPS27A UBA52 ANAPC10 ANAPC2	0.00843301	DOWN
KEGG_ASTHMA	CCL11 HLA-DOB HLA-DQB1 HLA-DQA1 HLA-DRA HLA-DPA1 HLA-DMA HLA-DRB5 HLA-DRB1 HLA-DRB4 HLA-DMB HLA-DPB1 CD40 FCER1G CD40LG MS4A2 IL3 PRG2 IL13 RNASE3 EPX IL10 HLA-DOA IL9 IL5 FCER1A IL4 TNF	0.00855264	UP
REACTOME_MITOTIC_M_M_G1_PHASES	MAD2L1 CENPA GMNN ORC2 KIF20A ZWINT CDC20 ZWILCH PPP2R1B PSMC6 SPC25 CDC6 NDC80 BUB1B CDC7 FBXO5 PSMB8 KIF23 CENPN ORC5 PRIM2 ORC4 KIF2C NUP37 PSMD3 PSMA5 ZW10 SKA1 PSMD7 MCM4 PSMD13 PSMB10 CDCA8 SEH1L CDT1 PSMD10 ORC1 MCM2 KIF18A PPP2R5A PSMD11 GORASP1 PSMA3 PSMC4 PPP2CB PSMD8 NUP85 BIRC5 RPA3 PSMA6 PMF1 DSN1 KIF2A PPP2R5E POLE2 PSMF1 AURKB PSMD5 PPP1CC PSMB3 NUP107 PSMA1 PAFAH1B1 PSMA4 PSMD9 SEC13 SMC1A NUP133 NUP43 CENPM STAG1 PSMC3 PSMA2 SMC3 PSMA7 BUB1 NDEL1 PSMD1 ITGB3BP PSMB7 RAD21 PPP2R1A E2F2 RANBP2 POLA1 PSMD2 PSMB5 ORC6 AHCTF1 PSME4 PSMD14 BUB3 PSMB6 MCM7 PSME2 PPP2CA B9D2 PSMD12 PSMB1 DBF4 PSMD6 CKAP5 PSME1 E2F3 PLK1 ERCC6L PSMB4 PSMB9 KNTC1 NSL1 PSMB2 MCM10 PPP2R5D RPA1 PSMC2 PRIM1 PSMC5 CENPQ MIS12 STAG2 INCENP PPP2R5C MAPRE1 CDC45 RPS27 PSMD4 CENPO PSMC1 ORC3 CDK2 MCM6 RPA2 RPS27A RANGAP1 TAOK1 POLE XPO1 MCM5 RPA4 UBA52 MCM3 CENPT NUDC E2F1 CENPI PPP2R5B POLA2 CLASP1 CLIP1 MAD1L1	0.0085903	DOWN
BROWNE_HCMV_INFECTION_12HR_DN	BAG2 THBS2 FLRT2 DLC1 ECM2 FGF7 CXCL12 LDB2 SDC2 RUNX1T1 PMP22 TUBA1A GZMK AKT3 RBMS1 JUN FYN CMA1 LRRC17 SPRY1 MAMLD1 GLI3 DAB2 TSPAN5 DENND3 SERPINE1 ERCC2 TBX5 ST5 INPP5B TUBB ZNF415 ASXL1 NR1D2 TBC1D8 RIN1 MAST4 TTLL1 SRSF3 KCNK2 ZIC1 ATXN1 ATP12A FGF5 SSH1 SNRPA GABBR2 STK17A CACNA1E MYH8 SMAD6 UBR5 APEX1 MID1 MAP3K5 HNRNPH3 UGCG ZNF516 ID2 EXOC6B MGEA5 PAIP1 U2SURP ZMYND8 PDGFRA VPS13B WDR45 ZMIZ1 SIPA1L1 ICK NUP155 PAFAH1B1 POP1 DHRS3 SPAG5 RUNX1 ZNF623 UBE2C ACSL3 TRAK1 SLC12A1 FHL2 PTP4A1 RABGAP1L RIN2 PRIM2 CDKN3 NMT2 AIM1 HMGCL TRIM2 PLCE1 VWA5A SERPINB1 CBR4 PTPRR	0.00864648	UP
GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP	PTGS2 RGS1 NR4A2 CXCL13 CYP1B1 CCL19 HBB JUN TUBB2A MAFF CXCL2 PRKAR2B TPSB2 DDIT4 APOC1 CCL20 ICAM4 TPSAB1 INHBA FXR1 APOE IL1B GBP1 RHAG IL1RN GADD45B CCL5 SERPINB2 INTS6 CXCL10 TRA2B PMAIP1 CCL8 BCL3 RSRC2 CXCL5 CDC42BPA CLK4 SMC3 PTX3 HIST1H2BK NFAT5 CXCL11 TCF7L2 SOD2 CXCL6 RRAS2 AKR1C1 CA1 ZBTB10 HIST1H2AC HIST1H1C	0.00866504	UP
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN	BAG2 BACH2 ITPR1 CD37 BANK1 SNN KLF2 TRIB2 CCR7 VPREB3 PDE2A ARHGAP15 GYPC CORO1A SH3BP5 CD19 PTPRCAP CD79A GMFG HHEX LIMD2 LCP1 SASH3 FAM65B RASGRP1 ARHGDIB TUSC3 PRKCB NAP1L1 RASGRP2 CD22 CELF2 CBFB RBM38 LSP1 DIRAS2 CYFIP2 MYBPC2 CDKN2C ANP32E BCL11A BCL7A AFF3 S1PR4 CPN1 ETS1 CHST7 LRMP PPM1E RIN3 KLHL24 RFX7 GFOD1 BRD3 RNF2 TNNI2 WAS FUS SMARCE1 NUCKS1 BTG1 PHC2 SLC25A37 FCHO1 ZCCHC2 CORO7 FAM111A CPLX2 BCAT1 PGP RNF219 RABEP2 STK4 STAG2 CKLF STX7 SYNCRIP TOP2B MKNK2 SYPL1 PUM2 SMS HIST2H2BE CNN3 TMSB10 PDE3B ATXN7L1 E2F2 DEK CUX1 PLEKHA2 SNX2 SRSF1 DNAJC9 CLIC1 USP25 UBE2D1 CDK19 BLVRB ARHGEF18 CRIP1 ID3 BTBD1 S100A10 CD55 CHD1 KIAA0101 PRKACB CAMKK2 FRYL SPAST PDLIM1 CPSF6 FH EZH2 NEDD9 CD24 GPD1L SERPINB1 FRAT2 CPM	0.00868545	UP
KEGG_PARKINSONS_DISEASE	CASP3 NDUFS1 APAF1 SDHB SDHC VDAC1 COX5A SDHD NDUFS2 NDUFB7 ATP5G3 CYC1 NDUFA10 SLC25A5 NDUFA9 NDUFS4 SDHA NDUFB3 ATP5D NDUFS3 ATP5B NDUFS7 UQCRFS1 UQCRC1 UQCRC2 ATP5G1 CYCS COX5B NDUFV1 NDUFA8 NDUFB6 NDUFC2 NDUFA6 ATP5F1 UQCRQ PPID NDUFC1 COX6A1 NDUFB5 COX7B ATP5A1 ATP5C1 NDUFB2 COX7A2 NDUFA5 NDUFA7 TH UQCR10 NDUFAB1 COX8A COX6B1 NDUFS6 NDUFA2 UQCR11 VDAC2 COX6C ATP5O ATP5J UBE2G1 ATP5H NDUFA1 NDUFV2 UQCRH UBB COX4I1 NDUFB4 COX7C NDUFB1 NDUFS5 UBE2J1 SLC25A6 NDUFB8 NDUFS8 CASP9 PINK1 UBA1 NDUFA3 UBE2G2 UBE2L3 COX7A2L VDAC3 ATP5G2 SLC6A3 UQCRB ATP5E PARK2 SLC18A1 NDUFA4 SLC18A2 SLC25A4 UBA7 SLC25A31 PARK7 HTRA2 COX6A2 SNCA UBE2L6 NDUFA4L2 SEPT5 GPR37 SNCAIP COX7A1 UCHL1	0.00871931	DOWN
ONO_FOXP3_TARGETS_UP	FOS RGS2 CCR7 JUN MECP2 CREM CCR2 CCR5 DDX5 IL10 CXCR3 GADD45B SLAMF7 CD38 ITGAE PDCD1LG2 DLK1 SOCS2 PAK1	0.00875735	UP
REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC	TUBB2B TUBB6 TUBA1A TUBB2A TUBB4A PFDN2 PFDN5 TUBB3 TUBA3C PFDN1 TUBA1C ACTB CCT3 CCT4 TUBB1 CCT7 TUBB4B CCT2 TUBA4A CCT6A CCT8 PFDN6 VBP1 TCP1 PFDN4 CCT5	0.00876574	UP
RICKMAN_HEAD_AND_NECK_CANCER_A	UCHL1 DMD PEG10 SFRP1 C8orf4 TSPYL5 PCOLCE2 MOXD1 NLGN4X PENK OLFM1 CD200 ANKRD6 ARNT2 CRABP1 TSPAN2 HOXD13 LIFR ODAM VASH2 NPTX2 TMSB15A SELE LSAMP BCL2 CLDN10 LAMA1 COL9A3 FABP6 PRAME STAR SPIB CLDN11 GPR27 COL9A2 MYCN DLX2 GPC4 OCA2 ADAM23 FRAS1 GABRP ADD2 NRCAM CXCL5 EDAR PON3 HSPD1 FRZB CYP24A1 IL13RA2 SYT13 PTX3 SOSTDC1 ZNF711 STXBP6 TNFRSF11B CLDN3 PARM1 TSPAN8 HPGD PLCB4 LGR5 MYB	0.00878606	UP
SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP	EGR1 RGS1 CLU TNS1 THBD SYNGR3 TIE1 HBEGF CYP1B1 PMP22 SMARCD3 DKK3 BLVRA BHLHE40 MCAM CD93 TGFB1 CHN1 IL21R MYLK MAFF PDLIM7 PFKFB3 SPARC LRRC17 MECP2 DSE CREM RGS16 RAB33A P2RX1 C5AR1 NCF2 ENG PROS1 SLC7A5 IRAK3 IER3 HSPA6 SLC2A3 ADAP2 CEBPB PPBP CCR1 TNFRSF1B SLA DUSP4 CCL20 FPR1 SLC16A6 COL7A1 C3AR1 EPHA4 TGFBI PTGES IGFBP3 NOD2 KIT SPHK1 ULK1 GNA15 SLC23A2 GM2A SKIL ALOX5 APOB TIMP2 CSF2RA PLAU NRG1 UPB1 CD1D MARCO CD14 RAB13 CYP1A1 FCGR2A GLUL HS3ST1 RRAGD ZNF134 TLR2 SGSH CHI3L1 HCK ABCA1 INSIG1 SLCO4A1 MPP1 BCAT1 RGS3 TLR8 YARS MAFG RARA SERPINB2 TNFRSF1A HRASLS CTSB MARCKSL1 MAPK7 SHC1 QSOX1 IFNGR1 KCNJ15 CKB CIAO1 RNASE2 SERPINB13 ZNF395 EPAS1 ACSL1 NBL1 CXCR1 PRSS23 DAPK2 AQP9 SMURF2 VEGFA DHRS3 THBS1 BST1 SMAD7 BIRC5 TMBIM1 ADM CXCL11 DHCR7 CLN8 IFNGR2 CYP27A1 GAB2 CD58 KDM5B SCML1 CDKN1A PPARD CD9 P2RY2 WNT5A ELF4 B4GALT5 CHKA PLIN2 ABCG1 FBP1 HMOX1 CDA HNMT PERP HIST1H2AE HPSE ANPEP SLC22A4	0.00888001	UP
LEE_AGING_MUSCLE_UP	FOS MFAP5 ATF3 TGFB1I1 RHOB HTRA1 ISLR SOX17 MECP2 ARHGDIB SV2A NTF3 POU3F2 TFAP2B HSPB1 ETV4 DDX5 AMY1A DCTN1 SMARCC2 EIF4A2 CKMT2 GDF9 BUB3 USP53 HEXA HSPA8 ACTR1B GADD45A ALDH1A1 ARF5 U2AF2 STARD7 HINT1 CDC42 RAB21 TGIF1 RAB1A PLAGL1 NAMPT TSPAN8 AP3S2	0.00889293	UP
PARK_APL_PATHOGENESIS_DN	GAL CES1 GPNMB MCAM RAB31 CORO1A JUNB PECAM1 SIRPA SLC29A1 COL4A2 SRF SRGN ZYX SPI1 VAT1 MNDA LSP1 CYBB FKBP5 PRKCA PRTN3 IFI30 RNASE3 GLUL BTG1 NFKBIE ELANE LYST LYZ PRCC PPP5C SMOX SERPINB2 QSOX1 ASAH1 S100P CKAP4 APP IL32 RAB27A GPI NR2F6 CTSD SRPK1 NEU1 SLC20A1 CEBPA	0.00891768	UP
TSUNODA_CISPLATIN_RESISTANCE_DN	PTGS2 CLU C8orf4 RHOB FN1 ITPR1 C3 FBN1 NPR3 KYNU C1S FSTL3 HLA-DPA1 HLA-DMA SLC7A5 CD74 IGFBP4 PTGES SGK1 SLC3A2 PDE3A ELL2 CPS1 LCMT2 FOLR1 FOLR3 CTSB MAGEA6 KRT7 TSC22D1 EPAS1 RABEPK S100P CASP9 GALNT2 B4GALT1 CFB ID1 ASS1 CRIP1 C4BPB PRMT3 WNT5A FBN2 ESRP2 SORD GPRC5A SLC27A2	0.0089344	UP
REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM	CSGALNACT1 SDC2 DCN CHST15 SDC3 CSPG4 CHST11 CSGALNACT2 DSE BGN UST CHST3 GPC1 HSPG2 CHST12 IDS CHSY1 GPC3 CHST7 GPC5 CHPF IDUA B3GAT3 AGRN HYAL1 B3GAT1 ARSB GPC4 BCAN VCAN B4GALT7 NCAN CHPF2 HEXA SDC4 HEXB SDC1	0.00909877	UP
TSUNODA_CISPLATIN_RESISTANCE_UP	CYR61 CTGF EFEMP1 G0S2 VIM C1S ARHGDIB PLAU DIO2 INSIG1 BRAP NT5E IFI27 VAV3	0.009109	UP
NABA_BASEMENT_MEMBRANES	NID1 LAMB2 LAMA4 LAMC1 COL15A1 COL6A3 COL4A1 COL6A2 LAMA2 COL4A2 COL6A1 LAMA5 COL18A1 HSPG2 LAMA1 LAMB4 NTN3 NTN1 AGRN COL4A4 COLQ NTNG1 LAMB1 NID2 COL4A5 LAMC3 USH2A COL4A3 COL4A6 LAMC2 LAMA3 LAMB3	0.00913515	UP
REACTOME_SEMAPHORIN_INTERACTIONS	MYL9 DPYSL3 MYH10 MYH11 RHOB NRP1 ITGA1 SEMA3A DPYSL2 FYN PTPRC TLN1 TYROBP PLXNC1 CD72 PLXND1 RAC2 PLXNB3 RRAS SEMA4D SEMA3E CRMP1 FES PIP5K1C CDK5R1 LIMK1 SEMA4A RHOG PLXNA3 ROCK1 PLXNA1 DPYSL4 SEMA7A PAK2 HSP90AB1 ITGB1 HSP90AA1 RND1 MYL6 MYH9 TREM2 RHOA PLXNB1 ARHGAP35 CFL1 MYL12B RAC1 CDC42 ARHGEF11 SEMA6A ROCK2 ARHGEF12 CDK5 PLXNA2 FARP2 MYH14 ERBB2 MET SEMA6D SEMA5A LIMK2 PAK1	0.00915444	UP
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G	ARHGAP29 SMARCA1 WWTR1 KANK2 CALD1 FZD7 CAMSAP2 LAMB2 TCEAL4 AMOTL2 CD93 ARHGAP15 RHOH LAMC1 SAMSN1 DIP2C PLS3 CORO1A GNG11 HCLS1 PTPRC TSPAN4 GMFG ZNF532 ULK2 NCKAP1L ENAH ANXA5 PTMS INPP5D ZFHX3 CD53 APBB1 CRTAP RAC2 ITGB1BP1 PCBP4 PTPN7 CCND1 GPC1 SLA MYC PIK3CG KIF21B IKZF1 SYDE1 PCGF2 TNFRSF12A LPP CNTRL HIP1 NKG7 RBFOX2 LRMP TMEM184B SELPLG S100A13 TAF4B BIN2 PLK2 PML CAPRIN2 HNRNPD RAB13 MAPRE2 AGRN ANP32B ZNF22 DEF6 TRIM27 ELL TXNRD3 PTPN22 NASP PPP6R1 DST RNASEH2B OTUD4 ATN1 POLD1 DUT RPS8 DDX51 NFIB MFSD11 ITGB1 NOC4L PTK2B CSK LMNA LAPTM4A LAMB1 PFN2 SLC25A12 MYOF MID1 DAG1 RHBDF1 SNRPG RBBP4 USP14 SCAF11 ABT1 KIF1C SH3BP4 ARHGAP4 NFYA CNN3 ZBTB33 CD63 VAMP3 DLG5 ZNF200 ATP2A3 TPP2 C9orf78 ITGAV USP7 SSBP3 REXO4 FAM114A1 DAZAP1 ANP32A FKBP9 SRSF1 SIK2 PRMT7 ZNF207 HDLBP POLR3E TJP1 DOCK1 CDK16 RPIA CDC42BPB INTS7 CCNJL VRK3 AMD1 LAPTM4B ORC1 S100A10 ANXA2 KATNB1 YIPF6 CTTN ELF1 SLC19A1 OCRL ADCY9 TMPO RAD51 MXD1 ADCY6 STIL TRIM14 ALDH7A1 MYB PDSS1	0.00920365	UP
CASTELLANO_NRAS_TARGETS_DN	AKAP12 RBPMS PLEKHO1 NCAM1 HTRA1 FBLN2 RPS6KA2 PKIA RBM38 LIMK1 CYHR1 CDKN2A ANKRD1 NRAS	0.00932133	UP
LU_TUMOR_ENDOTHELIAL_MARKERS_UP	PAMR1 MMP9 CHN1 HOPX PLXDC1 TWIST1 HSPA6 LCP2 ADAP2 STC1 FZD10 TNFAIP6 COL5A3 MXRA5 RPS11 VCAN ADAM12 PMAIP1 EGFL6 WDR77 TNFRSF21 POSTN	0.00935116	UP
NADLER_OBESITY_UP	CRYAB FLNA DUSP1 FBLN2 PLTP FXYD5 SERPINF1 PEA15 COL1A1 BASP1 HCLS1 LAPTM5 CSF1R CTSK TLN1 MRC1 BGN UCP2 CD53 MFGE8 C1QB LEP LBP FCER1G PLD3 SELPLG TPM4 IFI30 FCGR2A LRP1 CD68 ALOX5AP PFN1 PSAP CTSB NEDD8 PABPC1 MIF CKB CTSZ SEC13 MT2A PITPNA LGMN CFL1 GRN CAPG DAD1 ATP6V1C1 DYNLT1 LGALS3 CTSD CSTB CTSA CTSS TPD52 PLIN2 IFI27 POSTN	0.00938372	UP
CROONQUIST_NRAS_SIGNALING_UP	GPM6B SNN GPNMB SV2B CCL3 TUBB2A CD48 RNASE6 LY86 SASH3 GATM NCF2 CD86 CCL4 CX3CR1 ST8SIA4 DUSP6 CCR2 CYBB NCF1 TRAF3IP3 HOMER3 FCER2 IFIT1 TBC1D9 MALT1 MSR1 CCL5 TMPRSS15 SDCBP SCGB2A2 OSBPL1A ELF4 CEACAM6 RP2 GCNT1 CEACAM1 NRAS	0.00958096	UP
HUMMEL_BURKITTS_LYMPHOMA_UP	UCHL1 TUBB2B FHOD3 LHFP BACH2 TUBA1A PTBP2 WASF1 TUBB2A PRKAR2B SSBP2 APBB2 RCBTB1 SOX11 MME LEF1 BMP7 TCF3 VPREB1 NASP RNASEH2B CSE1L LZTS1 TERT HNRNPA3 SMARCA4 SLC35E3 RFC3 TCP1 C14orf2 ID3 ALDH5A1 TFDP2 RAP1GAP2 PRDM10 SERINC5 HADH	0.00960114	UP
PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_DN	NR4A2 NNMT MFAP4 FLI1 DOCK2 WISP2 MAFB ALDH1A3 CELF2 SIRPB1 RBP1 LYL1 STC2 RPL39L CA6 RAB3IL1 ACAN AHR PHIP FAM111A INSIG1 FOXG1 HEY1 PTPN18 MCF2L PDGFRA LSS FAM105A	0.00967015	UP
DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_DN	SYNM CNN1 RBPMS DLC1 CXCR4 CAND2 ROR1 COL1A2 PDGFRL BICC1 SSBP2 RAMP2 PTN LPXN IRF5 ENPP2 DOK5 CPA3 CLCN4 VCAN HMGN3 SERPINB2 BMP4 NPPB GULP1 HAS2 MAP2K5 PRKCZ PPP2R3A SOX4 FABP5 VLDLR STAMBP HMOX1	0.00972984	UP
ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION	FOS SYT1 CES1 CAV2 EGR2 CAV1 CRIP2 CDK14 G0S2 DPYSL2 RHOH LY96 OLFM1 MAPT CD79A SIRPA CSRP1 RUNX3 FNBP1 WDR47 FADS1 DAPK1 PRKCB GRK5 CSNK1E CEBPB CDH11 CCND1 MYC NELL2 IGFBP4 GYG2 GABARAPL1 GPSM3 SH2B3 SLC17A7 HOXD9 NPTXR ARHGEF1 MAN2A2 STARD13 CSPG5 IPO13 CD1E JAK1 CD99 SLC1A4 ATF5 MSX1 SMARCC1 CCK RAP1GAP ST6GAL1 IFITM1 PFKP GLG1 STAT6 ID2 ADO KDSR IL1RAP RNF113A HLA-E HIPK1 PPFIA3 CITED2 AK4 XPNPEP1 SEL1L3 HES1 UBXN7 FCGRT ATP1A1 UAP1 WNT5A ZDHHC3 ME1 CHN2 SORD PSEN1 TRIM2 VWA5A RCOR1 MYO10 GLCE STEAP1	0.00973019	UP
LU_TUMOR_VASCULATURE_UP	SPP1 PAMR1 MMP9 CHN1 HOPX FOXF2 PLXDC1 TWIST1 HSPA6 LCP2 ADAP2 STC1 FZD10 TNFAIP6 FJX1 COL5A3 MXRA5 ISG15 RPS11 VCAN ADAM12 PMAIP1 EGFL6 WDR77 MUC1 SCIN TNFRSF21 POSTN	0.00978084	UP
REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES	EVL ENAH LCK ITK HLA-DQA1 HLA-DPA1 HLA-DRB5 CD4 HLA-DRB1 LCP2 CD3D CD3E HLA-DPB1 CD247 ZAP70 LAT PLCG1 FYB GRAP2 WAS PAK2 VASP CD3G NCK1 PAK1	0.00984579	UP
CROMER_TUMORIGENESIS_UP	UCHL1 TNC FN1 SPP1 G0S2 COL5A2 MMP9 CCL3 COL4A1 COL1A1 THY1 COL1A2 SPARC ACTN1 COL4A2 LUM FAP PDPN IL6 SLC2A3 CXCL1 IFI6 RBP1 CHST2 NELL2 TNFAIP3 SERPINE1 COL3A1 PTK7 PXDN LRRC15 PLAU MFAP2 KRT16 ODC1 IL1B HHLA1 NTS APOBEC3C DEFB4A KRT17 MMP3 PLAUR MAGEA3 COL11A1 MMP11 SMOX MMP12 PFN2 MMP10 PLOD3 BMP1 MAGEA1 PPFIA1 LAMC2 MYO1B POSTN LAMA3 MMP1 LAMB3 OASL	0.00987562	UP
HAN_JNK_SINGALING_UP	CYR61 TNC DPT DUSP1 ANGPTL2 JUN CTNND2 TGFBI UBE2L6 CCND2 SGK1 IFIT1 TNK2 ISG15 FAM3C IL1RL1 CCL5 CXCL10 IRF9 USP18 ID2 TMSB4X IFIT3 SHOX2 RUNX1 LOX SOX4 EFNB2 IMPACT MAN2A1	0.00989054	UP
JACKSON_DNMT1_TARGETS_UP	CYR61 PTGS2 CRYAB THBS2 SFRP1 CCL2 IGFBP6 EREG FGFR1 JUNB ZFP36 RGS16 ENG GATA2 EPHA2 SOCS3 CXCL1 PARP1 BIN1 PHLDA1 HSPB1 IFIT1 ETV4 MX1 CDC25A ISG15 TRIM28 RELA CSF1 DAZL IRF7 CYP2E1 REEP5 PROCR RPA2 CSK HIF1A CEBPZ MAP2K3 POLR2A CXCL10 CTNNB1 IFNGR1 SLBP JAK2 EIF2AK2 IL1RAP EIF3A GPR12 IFIT3 HSPH1 PDGFA TRAF3 RAD52 HLA-G HMGA1 MRE11A TK1 TRAF4 BAG1 GTF2H1 TSG101 SEMA3C KLF4 CCNG2 NFE2L2 CDKN1A TRIM25 SLPI PLIN2 AHCY CHEK1 IL10RB ECT2	0.00997085	UP
REACTOME_BIOLOGICAL_OXIDATIONS	UGT2B17 UGT1A8 CYP2B6 UGT1A3 UGT1A6 UGT1A1 ADH1C UGT1A9 NAT2 SULT1B1 CYP2C18 CYP4F2 ADH6 GSTM4 NAT1 CYP4F11 GCLM GSTA2 CYP2J2 CYP4F3 CYP2C9 CYP51A1 UGDH PAPSS2 SLC35D1 ADH1A SULT1A2 AHCY TPMT UGT2B28 SULT1A1 MAOA MGST3 UGP2 MGST2 GSS GGCT CYP3A5 SULT1A3 CYP3A43 ALDH2 CNDP2 CYP2D6 CYP27A1 GCLC CYP4F12 CYP3A4 SULT1E1 CYP3A7 UGT2B4 GGT1 CYP24A1 SULT1C4 MAT2B ALDH1A1 OPLAH ACSM1 CYP2R1 CYP2C8 GSTP1 GSTO1 GSTM1 CYP4F8 CYP17A1 ADH7 MAT1A BPNT1 CYP2F1 CYP19A1 SMOX CYP39A1 MAT2A CYP4A11 CYP11A1 SULT2A1 CYP2C19 GSTA3 CYP2E1 GLYAT CYP27B1 COMT UGT2A1 CYP7A1 CYP2A6 SULT2B1 ACSM2B GSTA4 CYP1A2 CYP1A1 CYP7B1 FMO3 PAOX CYP11B2 CYP2W1 CYP2A13 SULT4A1 CYP11B1 PAPSS1 CYP26B1 POMC GSTA1 CYP26A1 TBXAS1 MTR CYP4B1 CYP21A2 PTGS1 FMO1 GGT5 CYP46A1 SULT1C2 FMO2 GSTM5 MAOB CYP1B1 NNMT ADH1B PTGIS PTGS2	0.0100127	DOWN
OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_UP	SHROOM2 GGH ANXA3 CXADR HOXB7 ACAA2 KRT19 GALE KRT8 KRT18 SRI ACADM AHCY SEPHS2 NDUFB7 CKS2 AIMP2 GMFB HSD17B4 ATP1B1 DNAJC7 GCSH TSPAN3 CAPZA2 RAB11A GOLGA1 TBCE CAPG GTF2B UBB QARS RAE1 PNN NDUFS8 DCUN1D4 CBX1 POLD2 HNRNPM XRCC6 KRT7 RBBP4 SRP72 TNFRSF1A FLII LAMB1 RBM39 EMG1 ELF2 PSMD4 RBBP7 PROCR SAFB CSE1L SET MARK3 CCNE1 BIRC3 LDHB SLC4A2 MMD DUSP4 LMO4 ARL4D SALL2 SPEG	0.0100404	DOWN
YAGI_AML_FAB_MARKERS	BAG2 ZBTB16 NAP1L3 NR4A2 MLLT11 TIMP3 MYH10 DLC1 CFH HDGFRP3 CAV1 NCAM1 AP1S2 TRPC1 RUNX1T1 NR4A3 RYR3 SCRN1 TRIB2 SERPINI1 TGM2 ELOVL5 CSTA LGALS1 GJA4 SFXN3 CD200 EVI2A TNFAIP2 ICAM2 LY86 LCP1 ULK2 CSF2RB IL23A ARID5B ANXA5 PKIA LAMA5 FADS1 PROS1 CD180 GATA2 TUSC3 SERPINE2 GIT2 CFP SAMHD1 TNFRSF1B TMSB15A BAMBI AIF1 GABRE SERPINH1 STAC SNTA1 ANKLE2 MYO16 GP1BA DEAF1 TPM1 ITGAX DOK5 RFC4 LAIR1 VCL PIM2 AHNAK ORAI2 TCIRG1 TIMP2 NTRK1 PKIG ITSN2 ITGA2B GOLGA8A DRAP1 MAST4 IL2RG PBX1 TYMP CLCN4 ELL2 STAT4 IFI30 GP9 UNC119 TPST2 MYL4 NLRP3 ATXN1 MCM3 TNFRSF4 FAM20B ADAMTS3 POU4F1 KEL TRPC6 DDHD2 CTSW CACNA2D2 COL11A1 RHAG MAX PLA2G6 CD68 ITGB3 MORF4L2 LDB1 MANBA SQLE CRISP3 IFNGR1 RAB27B MRPL33 TM7SF2 GAD1 DDB1 ZMYND8 CDC42BPA PAFAH1B3 FANCI NAE1 SLC7A1 GOSR2 GIPC1 PAQR3 PNN PCNA CTR9 RFC3 MPPE1 ILF2 ALDH1A1 AHCYL1 KIF2A AOAH NUP50 F2R TBPL1 SORL1 VPS13A CD164 AMD1 LAPTM4B NET1 CAPG S100A10 TGIF1 MED21 MAN1A1 CAST USP8 PSMG1 FGFR3 CD58 ZNF91 LARS2 TXNRD1 RRAS2 PTPN4 CAPN2 PDCD10 ALDH5A1 CYB5B UBXN8 CASP1 ITGA6 ACO1 TFDP2 PRSS3 HMGCS1 PIR IL10RB PLOD2 SLC25A1 TJP2 ELOVL6 CXADR DHCR24 PCCB TOM1L1 HOXA9 CPM GGH	0.0100868	UP
SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER	CHRDL1 EGR3 SFRP1 FEZ1 THBD DLC1 CXCL12 HBA1 PMP22 FBN1 JUN TCEAL1 PAX5 NPTX1 RBP4 TFAP2C CEBPD NR2F2 DUSP6 PCDH11X CD44 PTHLH CDKN2C CDH13 HIC1 BCL2 SFRP5 FOXA2 GPC3 NKX2-8 NTRK2 SLIT1 TBX1 GATA4 WT1 MYOD1 POU3F1 PRKG1 TNFSF9 TP73 CACNA1G FOXE1 APBA1 PAX6 CDH4 DCC ALX3 PAX7 AMN CYP27B1 GNAS TNFRSF25 HRK RARA PGR DSC3 HOXB13 NKX3-1 PPP1R13B KLHL35 CALCA MT3 CCNA1 GADD45G TBX3 EPHX3 KCNQ1 CRIP1 KLF4 LGALS3 NDRG1 CDX2 PYCARD LAMA3 VDR ETFA PXMP2	0.0101134	UP
ONO_AML1_TARGETS_UP	FOS P2RY14 RGS2 JUN MECP2 NKG7 PDCD1 SEMA4A CXCR6 E2F1 DDX5 CCNF FASLG GADD45B SLAMF7 CD38 CD244 PDCD1LG2 DLK1 IFNG GZMA PAK1	0.0103189	UP
SAGIV_CD24_TARGETS_DN	HSD17B6 GEM ATF3 HSPB8 CAV1 PPP1R15A EMP3 MCAM ADRB2 LAT2 CABP1 GDF15 PDGFB ICAM1 EPHB6 KLHL22 DUSP5 HOMER3 TRIM8 SPHK1 TIMP4 RNF25 PLAU ECM1 OGG1 FOXD1 ULBP2 CHAC1 NAGK ISG20 N4BP3 CST6 TRAFD1 LDB1 UROD RELB THBS1 BIK CTTN PRDX2 CDKN1A TUFT1 OASL APOBEC3B	0.0103403	UP
LE_NEURONAL_DIFFERENTIATION_UP	ANK2 SYT11 SYNGR3 SCG5 GABBR1 CNR1 KCNAB1 SNCAIP SCN2A KCNB1 SYT5 KCNK2 CHRNB1 KCND1 CA10 STX3	0.0103727	UP
JEON_SMAD6_TARGETS_DN	CTH DDC ERBB3 CENPA KIF11 CDH1 USH1C TOP2A CCNB2 DHFR KIF23 EGFR DHCR7 BCKDHA IRS2 UBE2S DDX39A CALCB NOTCH3	0.0105103	DOWN
BIOCARTA_CTLA4_PATHWAY	LCK ITK HLA-DRA ICOS CD86 HLA-DRB1 CD3D CD3E CD247 CD28 CTLA4 PIK3CA PTPN11 PIK3R1 CD80 ICOSLG GRB2 IL2 CD3G	0.0105654	UP
PID_BCR_5PATHWAY	FOS BCL2A1 CD79B JUN FCGR2B SH3BP5 PTPRC CD19 CD79A INPP5D BTK CD72 NFATC1 CD22 MAP4K1 PLCG2 DAPP1 PPP3CC PTPN6 ETS1 NFKBIA LYN PPP3CB PIK3CA RELA MALT1 POU2F2 IKBKB AKT1 DOK1 PIK3R1 MAP3K1 IKBKG ELK1 CSK HRAS MAPK8 VAV2 CAMK2G SHC1 PDPK1 RAF1 MAP2K1 GRB2 PPP3CA NFKBIB RASA1 MAP3K7 NFKB1 SYK PTEN TRAF6 RAC1 BCL10 MAPK3 MAPK14 SOS1 IBTK BLNK CSNK2A1 CHUK MAPK1	0.0105707	UP
WIKMAN_ASBESTOS_LUNG_CANCER_DN	MYO5A GIMAP6 ITGA4 TRAT1 MAFB CD86 MS4A6A UVRAG CCR2 FGL2 ATM MUSK PATZ1 LZTR1 MYO7A PRKACA FBXL12 PRKCSH HMGXB3 FNTA NIPSNAP3B PPIG FKBP1A RUNX1 GLRX SIRT6	0.010814	UP
BOSCO_TH1_CYTOTOXIC_MODULE	CH25H PLEKHO1 GZMK MYBL1 ADAM19 F13A1 P2RX5 FCGR2B RGL1 GIMAP4 RUNX3 ARNT2 CRABP1 CERS4 GPR171 TRAT1 GIMAP5 APOL3 IDO1 SH2D1A RHBDF2 PRKCQ ITGA9 BCL2 CD28 STAB1 IL2RA CDK6 ENPP2 FFAR3 NKG7 MERTK IRF4 PRKCA CTLA4 ISG15 CCR5 CMKLR1 SLAMF1 SOCS1 STAT4 LILRB5 IL10 PRF1 CXCL9 GNLY ATF5 GAS6 IL21 IFNB1 HAMP CD5 TNFSF18 CD38 HESX1 TXK SMOX CXCL10 GZMB USP18 DNA2 IL15RA CCL8 KLRD1 ADORA3 CCL7 RNASE2 RRM2 HERC6 PTGER2 HS3ST3B1 SSTR2 IFNG SDS IL12RB2 F2R TYMS RTP4 CXCL11 IL15 CDC7 MKI67 ABCB1 FUT2 BCL2L14	0.0108172	UP
ZHANG_TLX_TARGETS_36HR_DN	HMGN5 SLC4A4 ERI2 HMMR PRC1 EGLN3 TTK SHMT1 KIF11 CCNA2 CEP55 SMPDL3A TTPA GINS1 TOP2A DTL ORC2 IFT74 TBL1XR1 CHEK1 SLC12A2 ZWILCH RAD51AP1 TMEM30A MKI67 TPX2 RBBP8 THOC2 SPC25 EZH2 UPF3B CENPF SMC2 DEPDC1 EEA1 RIF1 PLK4 ARHGAP5 CENPE KIF23 APC NUSAP1 CENPN TMPO FMR1 ORC4 IFIT2 HAUS6 SKA1 MCM4 CHD1 NET1 KIF18A ROCK2 NAA15 SMC4 BRCA1 TYMS WDHD1 NUP85 NCAPG UBE2V2 NCAPG2 UPF2 FAM208B SUV39H2 TARDBP KIF2A DIS3 DDX46 SPAG5 SMC6 CA3 PRPF4B QSER1 PPP1R7 ZNF207 SRSF1 RASA1 PIK3C2A STAG1 SMC3 SERBP1 BUB1 DEK TIMELESS RANBP2 FANCI ZC3H7A POLA1 MPHOSPH8 LIG1 HAT1 CUL4B BCLAF1 PPIG MIS18BP1 SCAF11 CASP8AP2 CKAP5 RBM26 ZNF638 DNA2 COPS2 ERCC6L USP1 ASH1L KPNA3 SMARCA5 NOL7 CHAF1B ESF1 MCM10 PRIM1 TGS1 CENPQ KPNA4 CEBPZ STAG2 INCENP HNRNPU CDC45 ZNF280D TPR TSC22D4 RAD54L DNAJC2 SUZ12 EXO1 POLE XPO1 RFC1 BLM FAM111A NASP CCDC88A PIK3R1 TRIP13 ZNF148 ROCK1 PCM1 RBL1 PHIP TUBGCP5 PPAT HMGXB4 FANCA DNTTIP2 ARPP19 ZNF292 POU2F1 TIPIN CNTLN LIMS1 RAD51C ATM SHCBP1 MACF1 PSIP1 ADAMTS5 PEG3	0.011145	DOWN
BIOCARTA_CLASSIC_PATHWAY	C7 C3 C1R C1QA C1S C5 C1QB C4A C6 C2 C9 C8A	0.0113333	UP
WIELAND_UP_BY_HBV_INFECTION	CXCR4 GPNMB GZMK RAB31 IL10RA RGL1 CD48 LAPTM5 C1orf54 IFI16 ARHGDIB HLA-DQB1 TYROBP UCP2 TRIM22 PIK3CD CD53 HLA-DRA HLA-DPA1 HLA-DMA CD83 SRGN DRAM1 GIMAP5 RAC2 APOL3 CECR1 C1QB VSIG4 CD3D PPT1 LPXN HLA-DMB HLA-DPB1 FGL2 CD74 SP110 C3AR1 FCER1G RFX5 UBE2L6 GM2A WARS IFI30 GBP2 RNASET2 RARRES3 CXCL9 GBP1 SLC7A7 IGSF6 ISG20 LYZ MCM6 CD68 CD5L CD38 CCL5 CTSB FCGR1B CXCL10 PSMB9 TPP1 TAPBP PSME1 STAT1 PSME2 B2M RRM2 LAP3 HLA-E HLA-C DENND2D HLA-B CFL1 KPNA2 TARP PTTG1 HLA-A HLA-F UBE2C CTSC RAB27A TYMS PARP12 CXCL11 S100A10 PSMB10 SOD2 LGALS3 GZMA RAB20 PLAC8 IFI27 AURKA PRC1 PBK	0.0113927	UP
BIOCARTA_GRANULOCYTES_PATHWAY	SELL ITGAM PECAM1 ITGB2 ITGAL ICAM1 SELP C5 SELPLG CSF3 IL1A IFNG TNF	0.0114027	UP
WIERENGA_STAT5A_TARGETS_UP	EGR1 RGS1 CALB2 TUBB2B IGFBP5 CH25H CCL2 CFH SCHIP1 CDKN1C KLF2 SPP1 CCR7 MAP1A STAP1 BHLHE40 TGM2 LAMP3 CCL3 SAMSN1 BTG2 HSPA2 PLEKHA4 ARID5B CCL22 COL6A1 LTB ST3GAL5 COCH TTLL7 DDIT4 NCS1 CTSH GATA2 IL7R PRPS1 CD83 PHACTR1 DAPK1 GPR65 GGT5 HSPA6 SLC2A3 DAB2 TRIB1 DUSP5 BBX TULP3 IGFBP4 BATF3 PRDM8 A4GALT NTSR1 SNTA1 SLC2A14 ST3GAL4 GABARAPL1 PIK3IP1 FCER2 DCPS RABGAP1 HBZ PIM1 SEMA6C CCND2 PHLDA1 CD40LG IL18R1 TSC22D2 TRAF1 OSM OSBP2 PLAU POU2F1 TRIB3 MEX3D CD1B ENPP3 PLEKHH3 TLE4 UPK1A SLC9A7 IL3RA SPAG4 PLXNA3 CSF2 CST7 FCGR2A MIIP BTG1 FAM131A CD1A KLF6 OLR1 SLC25A37 DPYSL4 NOD1 TNFRSF4 NAALADL1 ABCA1 TGFBR1 RHAG GYPB SLC25A4 RAP1GAP MOSPD3 PHTF2 PPFIA4 GADD45B PFKFB4 PSAT1 CCL5 ENC1 IL18RAP IL4R CXCL10 DDN FPR3 CDHR1 ZNF609 EGFL6 CLEC4A EPB41 SH3BP4 TLE3 PLVAP CTNS CISH TRIM46 PTGER2 SQSTM1 CTSZ TRIM58 MUC1 MTHFD1 CKAP4 TARP DHRS3 AK4 STK17B GNPTAB HOXB5 FNDC3B SOCS2 ADM ARG2 UBAC1 SOS1 ARL4A RNF144A SLC2A10 MOB3B P4HA2 PLIN2 MAOA NDRG1 SLC6A9 NAAA CBS NFIL3 ITGA2 GALC TJP2 MYO10 P2RX4 CA2 EMP1 MAPK13 F2RL1 AMACR	0.0114128	UP
GILDEA_METASTASIS	MYL9 TAGLN TIMP3 IGFBP5 PRKCDBP FN1 COL5A2 SPARC IFI16 ARHGDIB BST2 GLIPR1 SRGN RAC2 DUSP4 IGFBP4 VAMP5 GBP1 SMARCA4 KRT7 TACSTD2 PTX3 SLC2A10 IFI27 KRT19 HNMT MPZL2 AKR1C3	0.0114248	UP
HEIDENBLAD_AMPLICON_12P11_12_DN	C1orf116 TMEM30B VILL ACSF2 ZBED4 LGALS4 GLB1 GAR1 CDK13 SYNGR2 CBX5 SAR1A TNFRSF8 GABRP MZF1 RBM15B JUNB	0.01143	DOWN
REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL14A1 PCOLCE2 COL21A1 COL5A2 MMP9 COL15A1 COL6A3 COL4A1 COL1A1 PCOLCE COL6A2 COL1A2 CTSG COL16A1 CMA1 COL4A2 TIMP1 COL6A1 CRTAP COL8A2 PRSS1 COL5A1 MMP2 SERPINH1 ADAMTS2 COL7A1 TPSAB1 MMP25 COL9A3 COL3A1 MMP7 MMP8 COL5A3 KLK2 PLOD1 TIMP2 COL13A1 TLL2 KLKB1 COL9A2 COL9A1 COL11A2 COL2A1 COL10A1 MMP14 MMP3 ELANE FURIN ADAMTS3 COL4A4 MMP17 MMP13 COL11A1 MMP16 MMP11 COL19A1 COL4A5 PPIB COL8A1 MMP10 PLOD3 BMP1 CTRB2 COL4A3 PLG TLL1 COL4A6 P4HB MMP15 MMP24 PRSS2 PLOD2 MMP1 COL17A1	0.0114338	UP
BROWNE_HCMV_INFECTION_18HR_DN	GREM1 FGF13 PTGIS TGFB1I1 PTRF RBPMS LOXL1 AXL DUSP1 ANGPTL2 ATP2B4 OBSL1 MAP1A IRS1 ANGPT1 CLIP3 PAMR1 EMILIN1 ITGAM MYLK SGCD GNG11 COL6A2 FYN RBMS3 CCDC85B LRRC17 ABCA8 CDH6 RPS6KA2 COL6A1 PDGFRB LRRC32 PNOC SSPN FADS1 GPR171 PRKCB PLXND1 RAC2 EPHB6 PDPN GLI3 CBFA2T3 RRAS DENND3 CD44 RECK MYC MSC PTGER1 THBS3 DOHH CEP250 VASH1 VAMP5 PCGF2 P2RY10 ACTA1 COL3A1 CIRBP HOXB1 RAB3B PRKACG FGF8 VAMP4 CTIF CRHBP FKBP8 RFX1 TPM4 RAD23A OGG1 L3MBTL1 SOCS1 TTLL1 MEGF8 GP9 KCNK2 GPR176 C1orf123 GSTA4 SHH TBCD KCNF1 EPX NME3 ZFR2 TEAD1 ARHGAP1 CACNA1A INSIG1 DST UROS GAS6 LAGE3 VCAN TRIOBP OCA2 ALDH3B1 SNX29 CDC42EP2 CD5L YLPM1 ADAM12 PNLIP S100A1 ZNF688 MAZ SNX17 NUMA1 BTBD2 NIPAL3 GUCY1A2 B2M MT3 ACOX2 APRT ETV6 PLXNB1 IFNG EPHX1 OPLAH ZFPL1 PTEN ATP5S MAP2K5 C21orf33 THBS1 ID1 SURF1 PSG9 FAH PLCD1 TRAK1 PCYT2 ADD3 GAS2 EXT1 CTSO TKT PSMB10 TNIP1 PTPRD RIN2 POLD4 WNT6 TNFRSF11B WWP2 DHRS12 RDH5 NDUFB7 DHFR ALDOB LPCAT4 CCDC88C SEMA5A ADH1A DDT CA12 ALDH7A1 SRI SLC22A18 VDR ASL SLC9A3 HSD17B2	0.011529	UP
KEGG_PRION_DISEASES	EGR1 C7 NCAM1 PRNP LAMC1 FYN C1QA IL6 C5 C1QB C6 PRKACG NOTCH1 IL1B C8B PRKACA STIP1 C9 ELK1 NCAM2 CCL5 MAP2K1 HSPA5 C8A IL1A HSPA1A C8G MAP2K2 SOD1 MAPK3 PRKX BAX PRKACB MAPK1	0.0115943	UP
LANDIS_BREAST_CANCER_PROGRESSION_DN	SRPX HSPB8 THBD DPT PRKCDBP HTRA1 CXCL12 CLEC3B IGFBP6 ANGPTL2 QKI FSTL1 NRP1 SORBS1 COL6A3 PENK COL4A1 COL1A1 FZD4 MFNG VWF LUM MRC1 COL18A1 CD34 MAP4 GHR ST3GAL6 COL5A1 GJA1 TGFBI COL3A1 BNIP2 AHNAK GAS6 DPEP1 H6PD LAMB1 FEZ2 CIDEC S100A6 PPP2R5A DERL1 CRIP1 ALAD MAN1A1 KLF4 ADIPOR2 ETFB DHRS7 HEPH NR1H3 DGAT1 SULT1A1 PDE8A DECR1 PLAC8 SQRDL PGM1 IDH1 ALAS1 PHYH GNAI1 EPHX2 BCKDHB	0.0116458	UP
REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT	SLC25A13 COQ2 VDAC1 TIMM8A CYC1 ACO2 ATP5B GRPEL1 TIMM13 ATP5G1 MTX2 IDH3G ATP5A1 TIMM17A CS HSPA9 SAMM50 TOMM22 MTX1 PMPCB TIMM10 TIMM8B GFER HSPD1 SLC25A6 COX17 BCS1L PMPCA TOMM20 FXN PAM16 TOMM40 TIMM44 SLC25A12 TIMM22 SLC25A4 TIMM17B TIMM50 TAZ TOMM7 TIMM9	0.0116541	DOWN
CERVERA_SDHB_TARGETS_2	CYR61 PEG3 AGTR1 CSGALNACT1 FILIP1L PCOLCE2 THBS4 NOTCH3 VGLL3 LEPR DUSP1 MOXD1 DFNA5 SERPINI1 SCG5 MCAM PRRX1 GPRC5B PFKFB3 NUAK1 IGFBP7 SH3BP5 SULT1C2 CDH6 FSTL3 CTSH CREB5 SERPINE2 FMO1 LTBP2 A2M ZAK ATP2B2 AREG GJA1 MATN2 COL7A1 SH3BGRL MLF1 ITPR2 HDAC9 C2 TGFB2 APOA1 FXYD2 NTS CGA F5 GPC4 SYT12 SUSD4 TFAP2A KIRREL STK17A CTBP2 MST1 MICB AFP TF PAH WLS TTR CXCL5 IL1RAP HS3ST3B1 DLK1 TNFSF4 PRSS23 GULP1 APOM CFB CADPS2 SOSTDC1 GAS2 METTL7A NMI NT5E MICAL2 CYB561 CCNE2 CLTB FBN2 AIM1 RAP1GAP2 SDHB SLC12A2 SLC26A2 ELOVL6 OVOL2 HKDC1 GALNT3 FMO5 DDC ESRP1 STEAP1	0.0116756	UP
MANTOVANI_VIRAL_GPCR_SIGNALING_UP	CCL2 MYH10 CCDC69 ACTA2 CXCL12 SPP1 C3 VCAM1 SLC16A4 CP IGFBP7 PAM SLC29A1 C1S ATP8A2 OSMR SOD3 LHX6 INHBB GPR18 STEAP4 CXCL1 MYC BCL2 CNTN6 RORA FSD1 SYN3 FST FLT1 TRPV6 IL10 CXCL9 GTF3C1 NRF1 KRT1 ITGB8 PUS1 MST1 CYP39A1 NYX PRKCE TRDN KLK11 PDE6B CCL7 DKK4 ITPKC PPP2R2A EPHX1 TARS2 IQGAP1 VEGFA SOCS2 ABCG5 EPB41L3 SERINC5 GALK2 HOXB7 CDC14B DSG2 HTATIP2 CA2	0.0117186	UP
GROSS_ELK3_TARGETS_UP	CYR61 CRYAB AMIGO2 CAV1 CXCL12 TCF7L1 CPE RAMP2 CCND1 CNN2 ZMAT3 TIMP2 CDC14A TUBA1B HCK GPX1 BMP4 ASS1 F2R MYLIP ARRB1 EDN1 RRAS2 NARS2 ABCG1 CPD	0.0118305	UP
ONDER_CDH1_TARGETS_3_UP	ZBTB16 TSC22D3 CRIP2 CYP1B1 LEPR KCNMA1 TCEA2 MAGED2 STC2 PRKCA KLF9 MAGED1 FTL KDELR3 RNASE4 ALDH6A1 WIPI1	0.0118443	UP
DURAND_STROMA_NS_UP	MYL9 GREM1 CRYAB GREM2 FEZ1 ADAMTSL3 RBPMS SYNGR3 ITPR1 PCDH9 FZD7 GPX7 PLCB1 DCN JAM2 MAP3K6 SH3BP5 PTPN13 TMEM45A LY9 ELOVL4 ATRNL1 SASH1 CTSK AIM2 ARNT2 UCP2 GDF15 TMEM109 DMPK GLIPR1 RAB6B CREB5 SLC2A3 HIVEP2 SLFN12 TCF7 DUSP6 SNAI1 STAG3 MLF1 BNC1 BICD1 PREX2 IL1RL2 GATA4 SLC4A8 TNFSF9 TLE4 LFNG HS3ST1 GPR176 OLR1 FETUB NOD1 GJB3 ZNF593 TMEM185B INSL6 EPOR NOX4 LPAR6 PIK3R5 AMPD3 FOXRED2 ACSBG1 MRPS31 OVGP1 RAB27B LPAR2 HHAT PDE3B WBP11 SPRY4 UNC5B REXO4 MT2A ABHD6 DDX19B H2AFJ F2R NIPSNAP1 CTSC EZR SLC16A3 PRKAG2 SCAMP5 PTPRG MAN1A1 KLF4 ARHGAP26 ICA1 LMO7 STXBP2 PARM1 NEDD9 GCH1 CHN2 MRPL35 PRRG4 LPCAT4 WWC1 CA12 ALDH7A1 LLGL2 KRT19 RBKS RUNDC3B RBM47 GPRC5A GPR39 PHYH GATA6 SRD5A1 RNF128	0.0118601	UP
REACTOME_SYNTHESIS_OF_DNA	RFC5 CCNA2 GINS1 ORC2 PSMC6 CDC6 PSMB8 CDKN1A ORC5 PRIM2 ORC4 POLD4 PSMD3 PSMA5 GINS2 PSMD7 MCM4 PSMD13 PSMB10 CDT1 PSMD10 ORC1 MCM2 PSMD11 PSMA3 RFC2 PSMC4 PSMD8 RPA3 PSMA6 POLE2 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 RFC3 PSMD9 PCNA CCNA1 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 POLA1 PSMD2 PSMB5 ORC6 POLD2 PSME4 PSMD14 LIG1 PSMB6 POLD3 MCM7 PSME2 CDKN1B PSMD12 PSMB1 PSMD6 PSME1 RB1 DNA2 FEN1 PSMB4 PSMB9 GINS4 PSMB2 RPA1 PSMC2 PRIM1 PSMC5 CDC45 PSMD4 PSMC1 ORC3 CDK2 MCM6 RPA2 RPS27A POLE MCM5 POLD1 UBA52 MCM3 RFC4 POLA2	0.011992	DOWN
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP	RGS1 UCHL1 GUCY1A3 HLF AMIGO2 TFPI CH25H TGFB1I1 AGTR1 RBPMS EGR2 ARMCX2 RGS2 SMARCA1 CD69 ACTA2 PDE4B NID1 TUBA1A THSD7A TRIB2 FZD7 RGS13 FSTL1 WFDC1 DNAJB5 SERPINB9 S1PR1 SAMSN1 CD200 EVI2A SPARC NPTX1 IFI16 FAM65B CREM ARID5B PALLD CLEC2B RAB33A GDF15 COCH TUSC3 ERG MAGED2 ZBTB20 DRAM1 SLC2A3 ZDHHC17 DAB2 RRAS DUSP6 CDC42EP3 SERTAD3 TOX TGFBR2 BAMBI HOMER3 PNRC1 MARK4 GSN FXR1 PLCG1 COL3A1 KIF3C APOE PHLDA1 HSPB1 TM4SF1 ALDH1A2 CRHBP NTRK3 CD226 ABI2 AHR MFAP2 PRKAR1A CALCRL ECM1 KLHL24 DGKE PPFIBP1 NTS ODF2 NFKB2 CYP1A1 GLMN TXNIP GBP2 KLF6 RPL35A E2F5 IRF7 TCN1 VCAN LPAR6 TCP10L PROCR GDF3 WSB1 IL1RL1 SLC7A11 LILRA2 SERPINB2 ENC1 RNF17 IRF9 GPR32 BNIP3L NRCAM DDX58 RB1 SPTBN1 TAAR2 UBA6 NCAN SENP7 TNFSF4 PRSS23 FBXW11 ALDH1A1 PLAT RUNX1 H1F0 ID1 HBP1 PSG9 SOCS2 HIST1H2BK STX6 ADD3 ARG2 PDLIM5 OPTN TMEM176B ARHGEF12 ZFYVE16 TCF7L2 ANXA2 SEPT10 TRIM5 DDAH2 CCNG2 UBL3 RPS6KA5 PDCD4 SOX4 IL13RA1 MXI1 BBIP1 TWF1 DDR1 NEDD9 ZNF217 DEPTOR HOXA5 EPS8 JUP QPRT MALL SLC39A9 ANK3 SLC35D2 HMOX1 IL17RB SORT1 P2RX4 CEACAM1 CA2 EMP1 F2RL1 HOXB6 TOM1L1 HPGDS GSTM4 FNBP1L NQO1 FAR2	0.0120213	UP
PID_PLK1_PATHWAY	ECT2 PRC1 CDC14B CDC25C PAK1 AURKA CCNB1 BORA KIF20A CDC20 TPX2 NDC80 BUB1B FBXO5 CENPE RAB1A CDK1 ROCK2 GORASP1 KIF2A PPP1CB FBXW11 BUB1 RHOA PPP2R1A PPP2CA PLK1 ERCC6L TPT1 TUBG1 STAG2 INCENP GOLGA2 WEE1 FZR1 NUDC CLSPN ODF2 PPP1R12A CDC25B NINL	0.0120323	DOWN
KAMMINGA_EZH2_TARGETS	ECT2 MAD2L1 PRC1 NEK2 GMNN AURKA TOP2A AHCY CCNB2 MKI67 SMC2 NUSAP1 TOPBP1 MCM4 MCM2 TFDP1 SMC4 EED RPA3 POLE2 AURKB PPP1CC KPNA2 PCNA RRM1 HAT1 CUL2 SETDB1 DBF4 H2AFZ PRIM1 DNTT IPO5 XPO1 RFC1 MCM3 RBL1 TACC3 NAP1L1	0.0120668	DOWN
GENTILE_UV_LOW_DOSE_DN	MEIS2 IGFBP5 NAV3 CXCL12 VEGFC C16orf45 SLIT2 SAMD4A CDK14 RBMS1 ANGPT1 RFTN1 PODXL ACTC1 TPST1 EHBP1 PTPRM ERC1 FNBP1 ZNF804A COL6A1 DDIT4 NAP1L1 CDH2 C2CD2 DDX10 WWOX FTO UTRN COL13A1 LAS1L CDH18 TBC1D30 PEX14 DYNC1LI2 PIBF1 POLA1 EIF4G3 IGF1R G6PD SIPA1L1 RASA1 PAFAH1B1 DOCK1 PTPRK EXT1 XYLT1 MICAL2 SEMA3C UBL3 AP3B1 PPP2R3A STX12 PRIM2 LMNB1 CRADD PHKB GBE1 MET SLC20A2 SEMA5A STK39 MYO10 HMGA2 SATB2	0.0120868	UP
HAHTOLA_MYCOSIS_FUNGOIDES_DN	ZBTB16 CES1 FLNA CD37 PRKCH HLA-DQB1 IKZF1 PIK3IP1 PRMT1 ZFP36L2 RPL31 CANX CDC42 CD160	0.0120886	UP
DASU_IL6_SIGNALING_SCAR_DN	CYR61 CTGF SULF1 PPP1R3C PRPS1 SERPINE1 TPM1 SGK1 LOXL2 PDGFRA THBS1 PSG9 ADAM10 ID3 TMBIM6 HMOX1	0.0121341	UP
PID_FCER1_PATHWAY	FOS DUSP1 WIPF1 S1PR1 JUN FCGR2B FYN HCLS1 PTPN13 LAT2 ITK INPP5D BTK PRKCB LCP2 VAV1 FCER1G LAT PLCG1 KLRG1 SPHK1 LYN MS4A2 PIK3CA MAP2K7 RELA PLA2G4A PLD2 PTPN11 IKBKB AKT1 DOK1 PIK3R1 FER MAP3K1 IKBKG PAK2 HRAS MAPK8 CBL PTK2 PLA2G1B FCER1A SHC1 RAF1 MAP2K1 GRB2 PXN RASA1 CBLB NFKB1 SYK MAP2K2 MAPK3 MAP2K4 SOS1 GAB2 CHUK MAPK1	0.0121614	UP
GEORGANTAS_HSC_MARKERS	FOSB GUCY1A3 GUCY1B3 HLF TFPI MMRN1 RBPMS CD37 KLF2 LIMCH1 HOPX PLS3 NPR3 PRKCH HLA-DQB1 BST2 CD52 PPM1F HLA-DQA1 CLEC2B GIMAP6 PGM5 GATA3 CEBPB CYBRD1 IDS IL6ST TRIM8 FAM198B PBXIP1 HSPB1 ROBO4 CRHBP SEC62 BIRC3 GBP2 MPL HOXB3 ATP8B4 TIPARP SPTBN1 HIST2H2BE SPINK2 HLA-E H1F0 HIST2H2AA3 HIST1H2BK RAPGEF2 COX6B1 ARG2 NRIP1 KLF4 IDI1 MECOM MLLT3 HIST1H2BF PDGFD TNFSF10 HIST1H2BG HIST1H2BD INPP4B HIST1H1C HIST1H2AE HIST1H3D HIST1H3H HIST1H2BC	0.0123219	UP
REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY	TUBB2B TUBB6 TUBA1A TUBB2A TUBB4A TUBB3 TBCD TUBA1B TBCB TUBA3C TBCA TUBA1C TUBB1 TUBB4B TUBA4A TBCE TBCC	0.0124807	UP
BONOME_OVARIAN_CANCER_POOR_SURVIVAL_UP	ZBTB16 IGFBP5 ARHGAP6 RUNX1T1 EFEMP1 LEPR THSD7A FAT4 LIMCH1 KCNAB1 RECK REV3L EID1 HERC1 SIRT1 KL PEX3 SRSF11 SEC63 ITM2B CERK CCPG1 TAX1BP1 GULP1 RB1CC1 TTC37 RAB2A UBL3 PDE8A TSPAN7 PSD3	0.0124956	UP
LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP	CYR61 MGP MFAP5 BCL2A1 ELN NLGN4X BNIP3 LGALS1 CAMK1 COL6A2 PTPRM TMEM45A MAP4K4 BTK PLXNB3 CSNK1E WNK1 COL7A1 L1CAM C6 PIM1 LZTR1 PTK7 STAB2 IL3RA SRPK2 FZD1 SLC1A4 ANKS1B SMO TSPAN9 ADRA1A HIPK2 IL12RB1 NAIP TNFRSF1A ANKS1A NRCAM SHC1 LTBR MCM7 BMP1 DAP3 PPP2R1A NME6 RTN4 FASTK SMAD3 ITGB5 BID COL4A6 F2R GAS2 PLAGL1 LGALS3BP FAT1 PLXNA2 DDR1 MET PTPRF PDCD6IP SH2D4A CEACAM1	0.0125023	UP
HUANG_DASATINIB_RESISTANCE_UP	TFPI ARHGAP29 NNMT LARP6 CAV2 PTRF ANXA1 CAV1 CALD1 PCDH7 ITGA5 DUSP10 FSTL1 ELK3 FXYD5 PRNP MSN PALM2-AKAP2 KCTD12 IFI16 OSMR RAC2 ZYX EPHA2 PARVA CDC42EP3 DPYD COL5A1 TGFBR2 MAP7D1 PDGFC ST5 TGFBI LYN PLAU SNAI2 DCBLD2 ELL2 REXO2 BTN3A3 BTN3A2 PSMB9 IL15RA JAG1 IFIT3 POPDC3 SOCS5 RAI14 INPP1 EPHB2 EXT1 EGFR CAST UBE2E3 PSMB8 RIPK4 NDC80 TNFRSF21 LIMA1 F3 MET GNG12 PGM1 UPP1 MYO10 LAMB3 AGPS F2RL1 AKR1C3	0.0125271	UP
KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP	CTGF AKAP12 RHOB ANXA1 FN1 CXCL2 VIM LCK HLA-DQA1 CALU ZFP36L1 NGF TAF1C IGFBP3 COL3A1 HGF DAXX MARK3 FLOT1 CSDE1 TXNRD2 CCNL2 ITGB8 PDCD5 TBCA TPR EIF3L RHOD AP3B2 RPL7A TP53I11 HNRNPA2B1 ARPC1B BNIP3L CTCF UGCG SGCB EFNB1 GOLPH3 OAZ1 POMP ALDH3B2 GALNT2 TAF10 PRSS23 ATP5I PRDX4 GLRX SOD1 MT1X EIF4E CYCS FGFR4 GOLGA4 NDRG1	0.0125368	UP
MORI_IMMATURE_B_LYMPHOCYTE_UP	MS4A1 RHOQ IL10RA PIP4K2A PTPRC LAT2 LY86 HLA-DMA CD83 CD72 GPR65 ADCY7 SAMHD1 DUSP6 SEMA4D HLA-DMB CD40 CD74 PTPN6 LIMS1 GDPD5 GGA2 LYN PML RGS14 BIRC3 MCL1 GMIP IFI30 BTG1 JARID2 CNR2 HCK LY6D EIF4A1 TAPBP TRAF3 ATP6V0B GNS GRN CAPG TMEM50B CAPN1 CTSS	0.0126078	UP
VALK_AML_CLUSTER_1	NR4A2 ATF3 MMRN1 FHL1 PCDH9 TRPS1 JUN LTBP3 KCNA5 SLC2A3 ATP10A MEF2C BMI1 SPIB KIF17 PRR16 IRF7 BHLHE41 SPAG6 COBLL1 SLC38A1 DPP4 SOCS2 BLNK MECOM PROM1	0.0126521	UP
MIKKELSEN_ES_HCP_WITH_H3K27ME3	PHOX2B KCND3 SLITRK3 SLC15A3 NTM ZNF804A NR2F2 ALOX12B PRDM8 PCDHA10 TBX5 NR2F1 TFAP2B TAL1 HBZ PCDHB11 PCDHB12 MPPED1 HOXA3 KCNIP1 DCC PCDHA2 TDRD1 ADCYAP1 CACNA1E PCDHA3 INSRR KCNS1 HOXD12 HOXD4	0.012709	UP
NAKAMURA_CANCER_MICROENVIRONMENT_DN	CTH AGPS RFC5 AURKA CDC20 CCNB2 DHFR NDUFA9 CDC6 SLC30A5 TXNRD1 KIF2C PSMG1 LSM4 TNS3 SPAG5 DHRS3 IMPAD1 TCP1 TARS BUB1 FANCI USP39 PSPH KLHL5 PA2G4 CARS SYNCRIP PSAT1 SLC7A11 IARS ASNS MARS BCAT1 TRIP13 ARTN HOMER2 RIPK2 RFC4	0.0127424	DOWN
BIOCARTA_IL5_PATHWAY	CCL11 HLA-DRA CD4 IL6 HLA-DRB1 IL1B IL5 IL5RA CCR3 IL4	0.0127502	UP
WILCOX_RESPONSE_TO_PROGESTERONE_UP	PBK ASPM MAP7 HMGCR HMMR PRC1 CEP76 KLF5 KIF4A TTF2 CYP51A1 SMPDL3B SHMT1 ELOVL6 CEP55 SMPDL3A CCNB1 DLGAP5 ZNF518A GALK2 ZCCHC10 IDH1 HMOX1 TOP2A HMGCS1 IFT74 KIF20A MUC5B SCD GK FAM105A CDC20 HSD17B11 PCSK6 CCNB2 EBP ABCG1 DNAAF2 SAMD9 CYB5B XRCC4 TMEM97 ATG2B LGALS8 CDC6 NDC80 MSMO1 CENPF YTHDC2 SMC2 BBS7 NPY IDI1 LSS MT1M RIF1 FDFT1 NUSAP1 CENPN FDPS ORC4 MON2 NPY1R ACAT2 NSDHL KIAA0101 TTC30A LIPG CDKN2AIP DHCR7 TBCCD1 CDK1 METTL7A TYMS WDHD1 TK1 NCAPG LARP4 ADAMTS20 HBP1 SUMO1 HJURP NUP160 NEUROD1 DNAJB9 MTF2 FANCI PRDM12 RRM2 KDSR HBS1L CXCL5 PDS5A KCNJ16 ZNF268 HMGB2 SYNPO2L CENPQ EIF1 HMGN3 CEP57 MVK INSIG1 DLX4 KLF6 C10orf12 KLHL24 PLA2G4A TLL2 SEC14L1 IFNAR2 HBD MAP3K8 KIAA0895 SGK1 NKG7 CNTN6 LDLR LPIN1 TRPC4 AREG CDKN2C ZBED2 TNFAIP6 PTHLH SHCBP1 BBS10 ITGBL1 FADS2 ETV1 PPL FADS1 MDM1 TDO2 HAND2 EVI2A C10orf10 ARHGEF3 HBB RGS2 THBD PEG10	0.0129226	DOWN
BIOCARTA_IGF1_PATHWAY	FOS IRS1 JUN IGF1 SRF PIK3CG PIK3CA PTPN11 PIK3R1 ELK1 HRAS MAPK8 SHC1 RAF1 MAP2K1 GRB2 IGF1R RASA1 MAPK3 SOS1 CSNK2A1	0.0129269	UP
PID_TCR_CALCIUM_PATHWAY	FOS PTGS2 RCAN2 JUN JUNB CREM NFATC1 BATF3 IL2RA CABIN1 CD40LG PPP3CB POU2F1 FOSL1 IL3 NFATC3 PRKACA CSF2 FASLG PPP3R1 IL2 PPP3CA IL4 IFNG FKBP1A AKAP5 RCAN1	0.0129878	UP
REACTOME_ER_PHAGOSOME_PATHWAY	PSMC6 PSMB8 SEC61G PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 TAP2 PSMD11 PSMA3 PDIA3 PSMC4 PSMD8 PSMA6 HLA-F HLA-A PSMF1 PSMD5 TAP1 PSMB3 PSMA1 PSMA4 HLA-B PSMD9 HLA-G HLA-C PSMC3 PSMA2 SEC61B PSMA7 CALR PSMD1 PSMB7 SEC61A1 PSMD2 PSMB5 PSME4 PSMD14 B2M PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 RPS27A UBA52 SEC61A2	0.0131921	DOWN
KEGG_PYRUVATE_METABOLISM	PCK1 PCK2 DLAT ALDH7A1 ACAT1 MDH2 DLD ALDH3A2 ME2 ME1 PDHA1 PC ALDH2 ACYP1 ACAT2 LDHA MDH1 ALDH9A1 PDHA2 ME3 LDHC ACYP2 HAGH PDHB LDHAL6B GRHPR GLO1 ALDH1B1 ACACA PKLR LDHB ACACB AKR1B1	0.0132435	DOWN
REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1	AURKA CDC20 PSMC6 SKP2 PSMB8 PSMD3 PSMA5 CDC23 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 UBE2D1 PSMC4 PSMD8 PSMA6 UBE2C PSMF1 AURKB PTTG1 PSMD5 PSMB3 UBE2E1 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PLK1 CDC27 ANAPC5 PSMB4 PSMB9 ANAPC1 PSMB2 CDC16 PSMC2 PSMC5 PSMD4 PSMC1 RPS27A UBA52 ANAPC10 ANAPC2	0.0132663	DOWN
REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX	GMNN ORC2 PSMC6 CDC6 PSMB8 ORC5 ORC4 PSMD3 PSMA5 PSMD7 MCM4 PSMD13 PSMB10 CDT1 PSMD10 ORC1 MCM2 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 E2F2 PSMD2 PSMB5 ORC6 PSME4 PSMD14 PSMB6 MCM7 PSME2 PSMD12 PSMB1 PSMD6 PSME1 E2F3 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 ORC3 MCM6 RPS27A MCM5 UBA52 MCM3 E2F1	0.0132887	DOWN
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN	ZBTB16 TIMP3 IGFBP5 EGR3 CCL2 S100B GPR183 CXCR4 CYP1B1 PMP22 RAMP1 CCR7 DUSP10 RASSF2 KCNH2 HBB S100A4 CSTA RHOH LGALS1 EHD3 P2RX5 IL10RA NEFH CAMK1 SLC43A3 CD48 CTSG LAPTM5 ACTN1 LAT2 ARHGEF10 SASH3 CSF2RB RUNX3 TYROBP CD52 PLXNC1 LTB FADS1 NCF4 GATA2 ITGAL TESC IL7R SLC7A5 FADS2 SLC16A7 ADCY7 LCP2 CBFA2T3 SPI1 LST1 CCND1 C11orf21 RBM38 DOK2 CHST12 SLA MMP2 CYBB HDC IGFBP4 STAB1 TEAD3 TGFBI TFR2 GATA1 FUT7 FLOT2 SLCO3A1 NOD2 TPM1 NKG7 MS4A3 SLC48A1 S100A9 PTPN12 KLF1 TMEM156 SELPLG CEBPE JUND BIN2 ANK1 MAGEF1 IL9R NFE2 HBD RGS14 IRF8 ITGA2B ZFP36L2 PRG2 AQP3 CCND3 GMPR BIRC3 CD82 CD33 CSF1 STK10 OGG1 SOCS1 MYCN CST7 FCGR2A PTPN22 MYL4 BCOR SLC1A4 CD36 SETX MGAT1 GALNT6 IL1RN FPR2 RMND5B ALOX5AP RARA SMOX C15orf39 CD244 FCER1A ZNF787 TPCN1 IL17RA TSC22D1 TUBA4A CIAO1 CFLAR EXOSC4 ACSL1 MBP RNF125 CCNA1 CRCP CKAP4 SH3BGRL3 TARP PLP2 TRAF4 GFI1B SLC16A3 LDLRAP1 CAPG TNFSF13 CD55 XYLT1 FHL2 MICAL2 SLCO4C1 GPR35 PDLIM1 RPS6KA1 PRKCD ASRGL1 CLC ABCC4 PDXK PIK3CB ITGA6 APOBR IGFBP2 DYRK2 PLAC8 KCNK5 PLCH1 ELOVL6 CEBPA GSR CYP51A1 IL6R E2F8 KBTBD11 IL7 ANPEP XK SLC27A2	0.01396	UP
KEGG_DILATED_CARDIOMYOPATHY	PLN DES TPM2 DMD ITGA7 ITGA5 TGFB1 ITGA1 SGCD SGCA ACTC1 LAMA2 IGF1 TGFB3 ADCY2 ITGA4 CACNA1C ADCY7 RYR2 ITGA9 CACNA2D1 CACNA2D3 SGCG TNNT2 TPM1 PRKACG ITGB7 MYL3 CACNG1 CACNB2 EMD ADCY3 CACNB4 TGFB2 CACNG3 ITGA2B TPM4 CACNG2 ADCY8 TNNI3 PRKACA MYL2 CACNG5 CACNG4 CACNA1D MYH7 CACNA2D2 TPM3 ITGA8 GNAS ITGA10 ITGB8 ITGB1 SLC8A1 ACTB TTN LMNA ITGB3 TNNC1 MYH6 ADCY1 DAG1 MYBPC3 SGCB ADRB1 CACNA1S ACTG1 ITGA3 CACNB3 CACNB1 ITGAV ITGB5 CACNA1F TNF ITGB4 PRKX ATP2A2 ADCY9 PRKACB ITGA6 ADCY6 ITGA2 ITGB6	0.014069	UP
KEGG_PROTEASOME	PSMC6 PSMB8 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMB3 PSMA1 PSMA4 PSME3 IFNG PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 SHFM1 POMP PSMD2 PSMB5 PSME4 PSMD14 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1	0.0141009	DOWN
ROY_WOUND_BLOOD_VESSEL_DN	C1orf116 PROM1 ERBB3 EPB41L4B KLF5 DSP SOX9 CEACAM6 CD24 RNF43 ATP1B1 SCGB2A2 S100P KRT14 ATP8B1 HIST3H2A SLC6A14 FBXO9 GABRP KRT15 F5 SFRP1	0.0141668	DOWN
BURTON_ADIPOGENESIS_7	FBLN2 PBX3 S100A4 FBN1 VCAM1 DNM1 CPE THY1 TMEM45A SLC29A1 TIMP1 WISP2 PROS1 SERPINE2 APBB2 CCND1 CD44 PTGS1 RBP1 IFITM3 VAMP5 TGFBI IL6ST PRRX2 TIMP2 TPM4 NONO XPO1 MARCKSL1 CD47 TINAGL1 BAG6 SLC6A8 SYNPO H2AFV UBQLN2 DLK1 TAGLN2 PLXNB2 PLP2 S100A6 RNASE4 CTTN PNP PLAC8 HMGA2 NQO1	0.0141825	UP
KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS	PIGL PIGO PIGV PIGG PIGZ PGAP1 PIGT PIGN PIGA PIGB PIGH PIGF GPAA1 PIGK DPM2 PIGP PIGC GPLD1 PIGQ	0.0142031	DOWN
ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP	RGS1 TSC22D3 CD69 PDE4B SORBS2 CD37 JUN ITGAM HLA-DOB LMO2 HLA-DQB1 HLA-DQA1 CD27 UCP2 TRIM22 GLIPR1 CD72 CX3CR1 SLC2A3 MR1 LCP2 CD44 IDS ZBED2 PTGS1 PTAFR GRM7 SATB1 TMEM156 MAP3K8 ZMAT3 ALOX5 ZBP1 YPEL5 MXD4 IKBKB TXNIP KLF6 C1RL RARRES3 LYZ RCBTB2 UBR5 FAM46C IL4R NRCAM UBE2H ID2 SYT17 TNFRSF14 AK1 DAPK2 PYHIN1 STK17B SAT1 ZNF91 POLD4 IL13RA1 KLK1 ALDH2 FUT6 LGALS9 ANXA4 GSDMB LLGL2 F11R ABAT	0.0143385	UP
REACTOME_CELL_CYCLE_CHECKPOINTS	MAD2L1 RFC5 CDC25C CCNB1 ORC2 CHEK1 HUS1 CDC20 CCNB2 PSMC6 CDC6 BUB1B CDC7 PSMB8 CDKN1A ORC5 ORC4 CCNE2 PSMD3 PSMA5 CDC23 PSMD7 MCM4 PSMD13 PSMB10 PSMD10 ORC1 MCM2 CDK1 PSMD11 PSMA3 RFC2 UBE2D1 PSMC4 CHEK2 PSMD8 RPA3 PSMA6 UBE2C PSMF1 PSMD5 PSMB3 UBE2E1 PSMA1 PSMA4 RFC3 PSMD9 PSMC3 PSMA2 PSMA7 ATR RAD17 PSMD1 PSMB7 PSMD2 PSMB5 ORC6 RAD1 PSME4 PSMD14 BUB3 PSMB6 MCM7 PSME2 CDKN1B PSMD12 PSMB1 DBF4 PSMD6 PSME1 CDC27 RAD9A ANAPC5 PSMB4 PSMB9 ANAPC1 PSMB2 MDM2 MCM10 CDC16 RPA1 PSMC2 PSMC5 CDC45 PSMD4 PSMC1 TP53 ORC3 WEE1 CDK2 MCM6 RPA2 RPS27A MCM5 CCNE1 UBA52 MCM3 ANAPC10 CDC25A ANAPC2 RFC4 ATM MAD1L1	0.0143667	DOWN
ASTON_MAJOR_DEPRESSIVE_DISORDER_UP	TPM2 MN1 CALD1 SAMD4A PENK JUN IGFBP7 ANKRD6 ZNF529 ZNF423 CTNNAL1 CELF2 MTHFD2 CEP250 BCL11A ACD REV3L LTBP1 TBC1D1 COMP ADAM22 PTH1R GSTM3 PCM1 PTPRT TNFRSF25 PPFIA4 TSC1 CCKBR DOPEY1 RPS21 DLGAP1 GREB1 TTR DDX23 HEXA RAB2A OSBPL2 XYLT1 ATP5F1 APC PLAGL1 RRAS2 AHCYL2	0.0144131	UP
GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_UP	FXYD6 PTRF GABBR1 MAFF VNN2 CREM ANXA5 HLA-DQA1 HLA-DPA1 CD83 SLC2A3 NACC2 LST1 SEMA4D DNM3 SDAD1 STAT4 MRFAP1L1 PDE10A U2AF1 IRF9 VPS13D GGPS1 ZBTB44 LEPROT SUPT4H1 WIPF2 HLA-G ATP6V1B2 MAP2K4 RAB21 FTH1 BAX CHMP1B DHRS1 RRAS2 FGF9 SDHC NAMPT	0.0144632	UP
MCBRYAN_PUBERTAL_BREAST_4_5WK_DN	CYR61 CHRDL1 BCHE FABP4 TNS1 PTRF PPP1R3C EDNRA NID1 TIE1 COX7A1 FHL1 CDH5 LPL QKI PRELP PER3 LAMA4 SORBS1 P2RX5 PFKFB3 CP EHD2 CSPG4 SLC16A2 TPSB2 SOD3 GRB10 HLA-DQA1 FSCN1 TMEM109 DMPK NNAT ST6GALNAC5 SH2B2 NOTCH4 KCNK3 STOM SLC7A10 NDN HSPG2 LTC4S EXTL3 IGFBP4 NFIC MPZ C20orf27 PTPN14 CD8A MLXIPL SH2B3 ETS1 GM2A MAPK8IP1 EHD1 KCNB1 GPD1 DBT PAQR4 DDX6 CCNK FABP3 IGFALS LIPA APOC2 ADRB3 AKT2 KCNK2 PEX6 AKT1 ZFAND5 AATK CYTH1 EPB41L2 OGT NR1D1 KDM5C WEE1 BLCAP UCP1 UBE3A HIPK2 GYS1 MYO1C NID2 PRKCE PDK4 ACLY KLF15 ART3 MBTPS1 RAB5B CIDEA ACACA BPNT1 RBBP4 EIF4G1 KIF1C PPP6R3 RNASE2 JAG1 GOLPH3 EPAS1 BMP1 PYCR1 PTGES2 PPP1R8 ACSL1 ATP6V0A1 PPA1 TPP2 GALNT2 ATP5SL CUX1 ERAL1 ACADVL SLC2A4 VEGFA AHCYL1 YKT6 ATPAF2 APLP2 LRP5 PDK1 UBE4A BCAT2 LASP1 LETMD1 SEH1L CARHSP1 SOD2 ECH1 PRKACB IDH3B SLC25A10 IMMT CSNK2A1 MLX DNM2 FABP5 TFRC ATP5D ACO2 CISD1 SUCLG1 RPS6KA3 MTCH2 PDCD6IP GK ECI1 SCD TBL1XR1 ACAT1 ACSF2 DLAT STEAP3 HCCS ACAA2 SFXN1 ETFDH EHHADH	0.0144822	UP
REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES	CTH DDC ACADSB NQO1 AGMAT OTC GCLM CKMT1B ACAD8 BCKDHB AUH ASL ETHE1 ALDH18A1 HIBCH SHMT1 TST HGD GSTZ1 SQRDL ALDH7A1 ACAT1 MCCC2 SLC25A15 CBS ALDH6A1 GOT1 AHCY IVD DLD GPT PSMC6 PSMB8 GLS ADI1 CNDP2 MCCC1 DLST SLC25A10 PSMD3 PSMA5 SUOX APIP PSMD7 PSMD13 PCBD1 GCLC PSMB10 SAT1 PSMD10 AMD1 TH DAO GCDH GLUD1 BCAT2 ARG2 PSMD11 PSMA3 TMLHE PSMC4 PSMD8 FAH ALDH9A1 ASS1 PSMA6 OAT QDPR PSMF1 PSMD5 PSMB3 MAT2B PSMA1 TAT PSMA4 GOT2 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 INHBC HSD17B10 BCKDHA PSMD2 PYCR1 PSMB5 SLC5A5 PSME4 OAZ1 PSMD14 PSPH PSMB6 DIO3 GRHPR PSME2 CKB PSMD12 SMS PSMB1 PSMD6 OGDH PSME1 MAT1A SLC6A8 ENOPH1 PSMB4 DIO1 FSHB PSMB9 PAH PNMT DBH PSMB2 ALDH4A1 PSMC2 PSMC5 SMOX MAT2A HAL CKMT2 CSAD PSAT1 PSMD4 PSMC1 BHMT TSHB AZIN1 ASNS SLC25A21 OAZ3 HAAO FTCD BCAT1 HPD PRODH AASS CPS1 MTAP GLS2 AANAT GLUL TPO PAOX CGA PCSK1 HAO1 DIO2 CKM ARG1 LHB ODC1 INHBE DBT AGXT INHA OAZ2 POMC BBOX1 INHBA MTR KMO GAMT HDC IDO1 TPH1 INHBB SRM GATM KYNU TDO2 PHGDH CDO1	0.0145209	DOWN
SMID_BREAST_CANCER_ERBB2_UP	LRRC31 ITGB6 DDC AKR1B10 HMGCS2 ACE2 NQO1 SLC44A4 FA2H ABCC6 TMC5 TSPAN1 PEX11A TMPRSS2 LPCAT3 PAPSS2 GSDMB GRB7 TSPAN8 CPD SCD ASPH PLEKHA6 QPRT GOT1 TRPM4 ABCC3 FUT3 UGT2B28 AIM1 SLPI CEACAM6 ERBB2 CD24 SCNN1A CD46 SEPT8 CDK12 PGAP3 SLC2A10 TSKU C2orf72 IL13RA1 ATP2C2 SLC37A1 PROSC NVL PSMD3 CRISP2 CORO1B CYB561 IGF2R SPTLC2 CD164 KIAA0100 TRAF4 SLC12A1 MMP15 BIK NUDT4 TRIM3 GGT1 ASS1 C2orf54 KIAA0319L P4HB EFNA3 MED24 PRMT7 MUC1 TMED2 MPHOSPH6 ANP32A WIPF2 G6PD SCGB2A2 FGG ACSL1 SQSTM1 ALDH3B2 SEC24D EPYC FASN GCAT TM7SF2 HPX CRISP3 CDK10 PNMT ALDH4A1 NCOA3 ABCA12 CLCA2 FFAR2 PIP GALNT6 SRSF6 CLIC3 CATSPERB PRODH LRP1 UBE2M ABCC2 PPP1R10 TRPV6 STARD3 SERHL2 MED1 ELL2 EIF5A AQP3 S100A7 CAMP SUPT6H S100A9 AR SCGB1D2 PADI3 LDLR NOL3 FGB TFAP2B FAIM2 KMO LBP SRPK3 SNPH DUSP6 WWC2 UCP2 ALCAM KYNU S100A8 LAMA4 APOD KRT24	0.0145392	DOWN
BIOCARTA_NKT_PATHWAY	CXCR4 CCR7 TGFB1 CCL3 TGFB3 CD4 CCL4 CCR1 CCR2 CCR4 CD28 CD40LG IL18R1 TGFB2 CCR5 CSF2 IL12A CXCR3 IL12B IL5 IL12RB1 IL4R CCR3 IFNGR1 IL2 IL4 IFNG IL12RB2 IFNGR2	0.0146703	UP
FARMER_BREAST_CANCER_CLUSTER_1	GZMK IL10RA CD48 GIMAP4 OAS2 GMFG POU2AF1 IFI44L LCK IFI44 ITK CYTIP CD2 GPR171 GPR18 LCP2 CD3D HERC5 CCR2 IFI6 SH2D1A CD8A IFIT1 MZB1 MX1 ISG15 CCR5 CD38 XAF1 FKBP11 TNFRSF17 OAS3 HERC6 IFIT3 CKAP2 GZMA OAS1 OASL RSAD2	0.0146734	UP
KERLEY_RESPONSE_TO_CISPLATIN_UP	NEFL ANXA1 CAV1 ACTA2 PLK3 BTG2 INPP5D GDF15 TRIM22 DDIT4 DRAM1 IER3 PHLDA3 ALDH1A3 FADS3 ISYNA1 SERPINE1 PDE4A ZMAT3 PLK2 ANK1 FOSL1 DDB2 TNFRSF10C GLS2 DGKA PROCR STK17A LMNA SESN1 RPS27L CXCL14 GADD45A PLAT EPS8L2 FDXR HSD17B3 CDKN1A FAS ANXA4 PPM1D	0.0146947	UP
MODY_HIPPOCAMPUS_POSTNATAL	EGR1 SYT1 ATP1A2 ENO2 RHOB STXBP1 KCNMA1 PYGM NPTX1 CX3CL1 KCNAB1 APBB1 PRKCB NRGN VAMP2 EEF1A2 RYR2 RAB3A BIN1 TYRO3 SYP BDNF GPD1 GRINA LDHB FBXW7 AIP SOX10 GRIA2 DGKZ GRIA1 IGHMBP2 RASGRF1 CCK PTK2B HRAS NTSR2 ATP6V1E1 SIRT3 PPP3CA ATP6V0C SH3GL2 ENO1 TPI1 MDH1 ATP6AP1 ATP6V1B2 COX8A MAPK3 ALDOA GPI NDUFB2 ATP6V1C1 ATP2A2 NAPA CLTB PRDX6 SDHA NDUFS2 VDAC1 GK	0.0150122	UP
MA_PITUITARY_FETAL_VS_ADULT_UP	CTGF RGS2 QKI G0S2 FGFR1 RGS10 FGF2 PIK3CD SEPT7 UCN CALCOCO1 PIK3R1 TNR ADCYAP1 VGF CDC5L FUBP1 RPA1 CTNNB1 IGFBP1 CCNG1 CDK1 PRKCD APOOL ING2 PIK3CB	0.0151237	UP
KORKOLA_EMBRYONIC_CARCINOMA_VS_SEMINOMA_DN	DMD FBLN5 SOX17 TCL1A CPEB1 PDPN PCSK1N KIT PRAME SLC43A1 ST7L TDRD12 MAGEB2 GIP KCNV2 OSBPL3 ELAVL2	0.0153188	UP
IVANOVA_HEMATOPOIESIS_STEM_CELL	EGR1 NR4A2 GEM PALMD NR4A1 SYT11 NRXN3 PDE4B ITIH5 SLIT2 CDK14 PKD2 PYGM CHN1 S1PR1 JUN COL4A1 MAFF NRXN1 EMCN FAM110B ARL4C TSPYL4 ULK2 SASH1 NES CAMTA1 TLN1 LRRC49 IFI44 ARNT2 ENG TRIM9 CTNNAL1 WWC2 TTC28 TCF4 DDIT4 GATA3 COL18A1 CERS4 ZBTB20 BAALC PITPNC1 SV2A ETV1 EPHB6 NOTCH4 KCNMB4 SEMA4C APBB2 IL36A MYCBP2 DUSP4 VAMP2 RBP1 DPEP3 DUSP5 ZRSR2 ITGA9 ROBO3 MAP4K2 PNRC1 KLHL26 DEF8 NKX2-8 CDKAL1 MPRIP SYN2 DNMT3A SLC23A2 SKIL NFKBIA IFT81 ROBO4 NTRK3 AGXT ACTN2 LYPD1 SULT4A1 SEMA3D INPPL1 S100A5 PRKG1 MBTD1 SERPINF2 PDC HYAL1 SMARCA2 LRRTM4 REST NFKBIE ZXDB GNL1 TBXA2R RBBP6 TEAD1 SEC14L3 PEAK1 DDX27 CYP2E1 CLPS KCNK15 FRMD8 RBM28 RPL10A GDF3 RPS6KA4 SART3 GAPDHS CHRNB1 USP34 KRT6A TCTN2 PPP1R9A TRAFD1 ESR1 PPP2R5C CCT3 PRKCE TCF25 POLR2A ANAPC13 MYOF ASH1L CD2BP2 OMP FAM168B SCAF11 KIF5A ETV3 LPAR4 PAIP1 ZMYND8 CHRNA6 NFIX RBX1 ITGA3 COBLL1 GATAD2A SOCS5 CXCL14 CSNK1D WHSC1L1 SREK1 BCL2L11 EFNA3 SERPINB8 LARP7 KCNJ6 LUZP1 SIAH2 SMAD7 TRIM3 NFAT5 ABCF2 PTPRK SOS1 LAPTM4B TCTA SMC5 GRSF1 IFIH1 PRKACB TSPAN13 CYP2D6 FMR1 WNT6 DGCR2 CDK2AP2 NCOA2 MUC13 UBA5 PPDPF PPFIBP2 VLDLR SULT1A1 PGD SCD BPHL PEX11A TSPAN6 MYO10 ENTPD5 IQGAP2 EMP1 SDC1 PCK1 PRKAA1 SLC16A5 ARHGAP32 HOOK1	0.0155722	UP
NEWMAN_ERCC6_TARGETS_DN	ADAMTS1 MFAP5 AEBP1 LBH PAMR1 SGCD PODXL RGS4 ITGBL1 RECK PTGS1 SERPINE1 NGF RAB3B ZMAT3 KCNK2 FGF5 GABBR2 COL11A1 PSG5 PSG6 SCUBE3 KRT34 PSG9 CDKN1A HAPLN1 SEPT11 SLC1A1	0.0156422	UP
REACTOME_GLYCOSPHINGOLIPID_METABOLISM	GBA3 ARSE GALC NEU1 GLB1 CTSA GBA SMPD1 HEXB SMPD3 SMPD2 GLA GAL3ST1 HEXA ASAH1 CERK UGCG ARSF ARSA PSAP NEU3 STS ARSB NEU2 SMPD4 GM2A ARSJ	0.0158539	DOWN
CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_UP	TPM2 CRYAB CASQ2 SMPX FHL1 MYOT ITGB1BP2 TNNT2 TNNT1 ACTA1 MYL3 HSPB1 ACTN2 MYH3 MYOZ2 MYL2 MYH7 ANKRD2 MYF5 CASQ1 ATP2A1 CSRP3 TNNC1 MYH6 TNNI1 HIST2H2AA3 FHL2 ATP2A2 PDLIM1 PPARA PPARGC1A	0.016233	UP
REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS	PIGL PIGO PIGV PIGG SEMA6D PGAP1 PIGT PIGN PIGA DPM3 PIGB PIGH PIGF DPM1 GPAA1 PIGK DPM2 PIGP PIGC PLAUR PIGQ	0.0163942	DOWN
HUMMEL_BURKITTS_LYMPHOMA_DN	BCL2A1 ARHGAP25 FNBP1 CTSH MDFIC CD44 CD40 NFKBIA S100A11 STAT3 BCL3 CFLAR SQSTM1 CRIP1	0.0165561	UP
ABE_VEGFA_TARGETS	PTGS2 EGR3 THBD EGR2 HBEGF PODXL A2M SLC4A7 CD1B ANGPT2 PPY CDR1 BPI ACE HERPUD1 MRE11A MCM2 RCAN1 PCTP	0.0166464	UP
WINNEPENNINCKX_MELANOMA_METASTASIS_UP	ASPM ECT2 PRC1 RFC5 CENPA NEK2 GMNN NCBP1 KIF11 CEP55 AURKA MELK CCNB1 DLGAP5 PLOD2 C9orf40 TOP2A ZWINT CHEK1 CCNB2 DHFR MRPS16 CKS2 GLRX2 SPC25 NANS CDC6 NDC80 CENPF UBFD1 KIF18B CKS1B SMC2 CDKN3 PAICS CENPN PRIM2 UGGT1 KIF2C IMMT RACGAP1 KIAA0101 GINS2 PRPF38B MCM4 CDCA8 MRPS17 NEIL3 KDELR2 CDK1 SRSF10 NUDT4 TYMS WHSC1 TK1 NCAPG BIRC5 NCAPG2 NCAPH MRPS10 RPA3 ARF4 SPAG5 HSPA4 CHORDC1 PTTG1 ENY2 CCT5 KPNA2 HSPD1 PTTG2 PCNA RSRC1 TARS OLA1 BUB1 SUPT7L TAF1A CHTOP TIMELESS SSR3 PHF14 DNAJA1 RRM2 CNN3 HSPA5 FAM98A H2AFV DTYMK NME1 ZNF587 ATAD2 SNRPG KNTC1 CCT7 SMARCA5 IPO7 RBMX CCT4 CDC45 CACYBP SRP19 RAD54L MCM6 DSCC1 EXO1 GEMIN6 XPO1 GPN3 RANBP1 KIRREL PWP1 DONSON CDON PSMC3IP NASP HTRA2 DDX18 OGG1 GMPS TCOF1 DCBLD2 C8orf33 RFC4 CLASP1 MSH6 SHCBP1 GJC1 PCDH17 CTNNAL1 MAP4K4 CREM RHBDL2 FERMT2	0.0166473	DOWN
WIERENGA_STAT5A_TARGETS_DN	NAP1L3 TPM2 GUCY1B3 SDPR MEIS1 CXCR4 WASF3 BANK1 ITPKB WFDC1 EAF2 SLC24A3 ANGPT1 CD93 JAM3 GJA4 EMILIN1 SERPINF1 TCEAL1 ARHGEF3 MYLK CAMK1 CORO1A GNG11 PECAM1 CTSG SALL2 ACTN1 IFI16 RASGRP3 VWF ITGB1BP2 TLN1 PPM1F PROS1 CLDN5 ARAP3 SELP PLEKHO2 ZYX C5 FCN1 PCYOX1L PLCG2 LST1 CCND1 DENND3 PLEK CHST12 GP1BB BAMBI ILK CR1 CD84 VASH1 ADORA2A BIN1 FCER1G OGFRL1 GP1BA BATF TRIM8 SCPEP1 PADI4 DOK3 ETS1 MS4A3 ITGB7 XYLT2 CD96 CTIF TSPAN32 SH3PXD2A NOTCH1 DAAM1 NBEAL2 USP20 LY6G6D SAMD14 IRF8 PLCB2 TPM4 CD14 PBX1 GFOD1 CLCN4 STX1A GP9 TTC27 PTGIR CAPN11 MPL PF4V1 MILR1 NINJ2 TMEM63A TPM3 LYZ TSPAN9 NFIB PLEKHG3 GPX1 STX11 DYRK1A LILRA2 SMAD6 GP6 FCER1A CD47 LGALSL PRKD2 IRS2 IL17RA RUFY1 NDUFAF3 ALOX12 ZNF185 DLK1 DCLRE1A CGRRF1 PLXDC2 ITGB5 PDIA5 LHFPL2 TNNC2 MRPS14 CTDSPL PSTPIP2 ROCK2 HIST1H4B SLC9A1 PDLIM1 SLC37A1 MGLL TUBGCP4 EFNB2 DEPDC1 CD9 LCN2 PPIF PSRC1 MARCH5 DEPTOR MANSC1 ARMCX5 NAT8B SLC12A2 ASAP2 MTMR11 ACOT11 CLCN2 C3orf52 HGD EFHC2 ADRA2A TTK EPHX2 IL7 FAR2 C1orf116	0.0166479	UP
REACTOME_G1_S_TRANSITION	CCNA2 CCNB1 ORC2 PPP2R1B DHFR CDK7 PSMC6 CDC6 CKS1B SKP2 CDC7 FBXO5 PSMB8 CDKN1A ORC5 PRIM2 ORC4 CCNE2 PSMD3 PSMA5 PSMD7 MCM4 PSMD13 PSMB10 CDT1 PSMD10 ORC1 MCM2 CDK1 TFDP1 PSMD11 PSMA3 PSMC4 PPP2CB TYMS PSMD8 RPA3 PSMA6 POLE2 PSMF1 CCNH PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PCNA CCNA1 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PPP2R1A POLA1 PSMD2 PSMB5 ORC6 PSMD14 SKP1 RRM2 PSMB6 MCM7 PSME2 PPP2CA CDKN1B PSMD12 PSMB1 DBF4 PSMD6 PSME1 RB1 PSMB4 PSMB9 PSMB2 MCM10 RPA1 PSMC2 PRIM1 PPP2R3B PSMC5 CDC45 PSMD4 PSMC1 ORC3 WEE1 CDK2 PKMYT1 MCM6 RPA2 RPS27A MAX POLE MCM5 RPA4 CCNE1 UBA52 MNAT1 MCM3 TK2 E2F1 CUL1 CDC25A POLA2 MYC	0.016662	DOWN
LY_AGING_MIDDLE_UP	THBS2 DPT HTRA1 COL15A1 PTGS1 FMOD COMP CST6 SERPINB2 MMP12 MMP10 CRYBB2 TNFRSF11B	0.0166668	UP
REACTOME_SULFUR_AMINO_ACID_METABOLISM	CTH GCLM ETHE1 TST SQRDL CBS GOT1 AHCY ADI1 CNDP2 SLC25A10 SUOX APIP GCLC MAT2B MAT1A ENOPH1 MAT2A CSAD BHMT MTAP MTR CDO1	0.0167004	DOWN
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN	WDR78 IL20RA ADH1C FMO5 AKR1C3 C1orf116 SLC22A4 PROM1 MYO1D NQO1 SLC27A2 SLC44A4 PIGR IMPA2 SCGB2A1 TOX3 PDZK1IP1 SLC16A5 GCLM CRYL1 AGR2 EPB41L4B CAPN9 SPAG1 CLDN7 TFF3 FUT2 TMPRSS4 CAPN5 TMC5 DHCR24 TSPAN6 ATP10B TSPAN1 SELENBP1 C1orf106 COBL VILL TJP3 PSENEN SPA17 VWA5A FKBP1B PLCE1 EPPK1 SLPI POR CSTB ALDH1L1 TNFRSF21 ELF3 BACE2 TSGA10 TACC2 HRASLS2 MUC4 LCN2 MUC13 SLC2A10 VPS37B MGLL ANXA11 IFT57 AGBL2 MT1E SERPINB7 KATNB1 CIB1 CD55 DNAH7 WDR13 EZR TRAK1 ZFYVE21 ASS1 SERPINB6 CFB TTC12 PRDX1 MUC1 ABLIM1 SYBU EFCAB1 PRSS23 EFCAB2 EFHC1 S100P ALDH3B2 VNN3 PI3 CKB HIST2H2BE SPAG6 KRT14 KLF8 KRT7 IQCA1 VTCN1 SCGB1A1 TUBB4B HYDIN DNAH2 P4HTM ZBBX NEK11 KRT4 MSMB RIBC2 DNAJA4 CASC1 C19orf33 UPK1B DNAAF1 TMEM40 MUC16 ARMC4 GSTA3 CCNO ALDH3B1 C9orf116 SERPINB3 KCNE1 CLIC3 TRAF3IP1 NMU TMEM231 SIX2 ATP12A CCDC81 PTPRN2 DNAH9 ALOX15 FAM131A DUOX1 TEKT2 ARSD FAM174B PACRG DNAI1 WFDC2 AQP3 TUBB3 B9D1 ZMYND10 CETN2 CHST6 DNAI2 DNALI1 LZTFL1 TPPP S100A9 GSTA1 FOXJ1 TTC9 IQCG CLDN10 FAM149A CYP4B1 SYNGR1 CR1 TNFSF11 CXCL1 POU2AF1 CD19 PIAS3 BASP1 PAX5 TUBB2A TCL1A RRAD MS4A1 VPREB3 TUBA1A BANK1 SORBS2 LTF TPPP3 CR2 NBEA CES1 AHNAK2	0.0167132	DOWN
LEE_AGING_NEOCORTEX_UP	FOS MYL9 CRYAB FXYD6 NR4A1 APOD CCL21 SPP1 LCAT JUNB C1QA VIM ITIH3 ICAM2 VAMP1 STOM KCNA1 PTGS1 CD40 TUBB GNA15 WWOX ALDOC AVP OXT DDIT3 LIMK1 AKT2 MAG RHOG CSNK1G2 SET VPS72 RRAGA M6PR CD68 GPX1 EEF2 PSAT1 PPP2R5C LAMB1 DNAJA4 UBC CTNNB1 RUFY1 CKB HSP90B1 B2M MOG GFAP PPIA POLR2F CTSZ P4HA1 CSNK1D GADD45A VEGFA PPP1R2 DHX15 ID1 DLG1 SAT1 S100A10 ATP1B3 CYB561 NAPA HSD17B12 CMPK1 STXBP3 LGALS3BP CD9 CTSD RAB14 PHB CTSS SEC23B NDRG1 RAB4A IFI27	0.016739	UP
BRUECKNER_TARGETS_OF_MIRLET7A3_DN	DPYSL3 SFRP1 NNMT BCL2A1 SPOCK1 FN1 EFEMP1 CALD1 DFNA5 LBH PLA2G16 GPRC5B SPARC VIM COL4A2 MFGE8 AKR1B1 CXCL1 GPC1 COL5A1 PMEPA1 NRP2 MATN2 PTGES CD70 LYSMD4 PLK2 LOXL2 TGFB2 DIO2 ATOX1 EPB41L2 COL11A1 CXCL3 RPL7A ANXA10 HSP90AA1 MORC4 TRAM1 CXCL5 ACTR3 EIF4G2 CORO1C PRSS23 MT2A COL4A6 BZW1 LASP1 MT1X EIF5 GALNT10 RIN2 GALNT1 GLS FLNB LGALS3BP PTPRF ANXA3 PPARG AKR1B10	0.0167747	UP
LEE_NEURAL_CREST_STEM_CELL_DN	FOS CHRDL1 LGI1 DMD NAV3 FAM107A HTRA1 SORBS2 EFEMP1 SPG20 SLIT2 QKI CAPN6 WASF1 MAFF PLEKHB1 MPPED2 SPRY1 ARL4C GATM PALLD GDF15 COCH TRIM22 TTYH1 CREB5 DTNA EPHA2 WNT5B DUSP6 FUT9 NELL2 HDC BCL2 BEGAIN MFAP3L AGPAT4 BMP7 FJX1 COL9A3 ETV5 IGFBP3 C1orf61 BTG3 NPY2R FGF8 LZTFL1 ZMAT3 DOCK3 PLK2 NOTCH1 FUT8 FGF17 DDB2 CD82 KIAA0754 ZIC1 PRR16 HSPA4L TKTL1 SLC1A4 CEP290 SPRY2 GAS6 FOXG1 NACA EMX2 SIX3 ZNF236 FABP7 COL4A5 ZBBX PMAIP1 TCEB1 NOS2 FEZF2 SMS HTR2C SOX3 LHX2 CNTNAP2 ZMYM2 DLK1 PRSS23 HLA-C WIF1 TNFRSF10B HLA-B COL4A6 C14orf159 PDLIM5 PSTPIP2 SAT1 HAUS6 MTUS1 PLAGL1 CD9 CROT CD46 SYNE2 SPON1 FBN2 TRIM24 F3 ENPP4 EFNA1 DSP LGR5 GALNT12 CA2 FZD5 PROM1 GRAMD1C	0.016909	UP
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN	IL20RA GRAMD1C DEFB1 ACADSB HOOK1 PROM1 KIAA1324 SLC27A2 TTC39A ERBB3 PDZK1IP1 PERP PEX7 MYB VAV3 RAB11FIP1 PADI2 ABAT ABCD3 SORT1 MYO6 LAMA3 GALNT7 TJP3 OPN3 SERPINA1 PTPRF MRPS30 CD24 SCNN1A ABHD11 TMED5 CLDN3 EPN3 LETM1 MLPH PDCD4 ISOC1 LRBA IER5 AUTS2 GPR87 CADPS2 XBP1 RAPGEF5 TBX3 ZNF750 ANXA9 ALDH3B2 KRT14 MMP10 SHANK2 DNAJC12 DSC3 ASNS ATP6V0A4 DST ERBB4 SLC1A4 MDK FAM174B MAST4 TBC1D8 PLK2 TM4SF1 CELSR1 TP63 STC2 KIAA0040 AREG SLC19A2 CELSR2 CEBPD DTNA MAGED2 GDF15 PRKAR2B WFS1 ZDHHC11 GRB14 CFD ARHGAP29 ACTG2	0.0169628	DOWN
COATES_MACROPHAGE_M1_VS_M2_UP	TUBB2B ENO2 PTGER3 FILIP1L CFH CXCR4 AXL CADM1 P2RY13 COLEC12 PLA2G16 GATM HLA-DQA1 ATP6V0E2 ADA HAUS2 AIF1 GJA1 OGFRL1 TGFBI MAF GALNT11 SFI1 RCN1 MARCO TM7SF3 ARSB TXNIP C14orf79 KCNJ10 DST COMT SLC7A7 CRIM1 MSR1 HMGN3 SLCO2B1 RCBTB2 PPP2R5C TOR3A TTC3 MARCKSL1 NRCAM RASAL2 FGD2 RFX3 GLO1 FAM135A CXCL14 PLXDC2 ACYP2 CAP1 SRD5A3 RAPSN ALAD OCEL1 SLC35A1 PLBD1 LAMA3 RMND1 CAPN5 BCKDHB	0.017129	UP
REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE	TFPI THBD SERPING1 F8 F13A1 VWF PROS1 F10 A2M GP1BB GP1BA FGB KLKB1 PROC GP9 F5 F11 PF4V1 FGA F13B PRCP F2 GP5 F7 F9 SERPINC1 FGG PF4 KNG1 F12 C1QBP F3	0.0172734	UP
REN_BOUND_BY_E2F	HIST1H3D MAD2L1 CENPA TTK HIST1H2AC CCNA2 HMGB3 TOP2A CHEK1 CDC6 NDC80 SMC2 UNG CENPE RAD51 PRIM2 CSTF1 UMPS ORC1 CDK1 SMC4 RFC2 TK1 RPA3 HIST2H2AA3 PTTG1 RFC3 PCNA PRKDC MSH2 RRM1 H2AFX E2F2 SUPT4H1 POLA1 BUB3 HIST2H2BE DBF4 E2F3 RB1 CBX5 FEN1 H2AFZ MLH1 HMGB1 TP53 CDK2 RAD54L MCM6 MCM5 DUT POLD1 NAP1L4 MCM3 BRD2 RBL1 HLTF CDC25A RFC4 POLA2 BARD1	0.0173318	DOWN
BIOCARTA_EPO_PATHWAY	FOS JUN STAT5B PTPN6 PLCG1 EPO STAT5A ELK1 EPOR HRAS MAPK8 SHC1 JAK2 RAF1 MAP2K1 GRB2 MAPK3 SOS1 CSNK2A1	0.0175709	UP
NAKAJIMA_EOSINOPHIL	RGS1 P2RY14 CFD SYNE1 CCL3 CAMK1 SLC29A1 CREM CCL4 IDO1 P2RY10 ALOX15 CNR2 OLR1 PLAUR OLIG2 IL5RA PNPLA6 MARCKSL1 CCR3 ADORA3 RNASE2 S100P SMAD7 HES1 CLC FBP1 TFF3	0.0175745	UP
HARRIS_BRAIN_CANCER_PROGENITORS	MGP ARHGAP29 LARP6 CAV1 ARHGAP6 SCG5 S100A4 COL6A2 COL6A1 BGN AOX1 TMEM212 MIA GJA1 SCG3 BFSP2 FOXC2 CASP4 NINJ2 TEAD1 CYTL1 OPCML GPR17 SRPX2 KAZALD1 KCNA4 LGALS2 DHRS3 S100A6 CAPG WNT5A PID1 PAPSS2 DDC	0.0176619	UP
MAHADEVAN_GIST_MORPHOLOGICAL_SWITCH	CTGF TPM2 SPOCK1 SPP1 ELMO1 CDH6 FSCN1 MMP2 CDH13 TFPI2 MMP3 ITGA3 PDLIM1 NEDD9 MYO10	0.0179933	UP
LEIN_PONS_MARKERS	AHNAK2 AKAP12 TNS1 DPYSL3 HSPB8 S100B TSC22D3 PMP22 SPP1 FSTL1 ENTPD3 P2RX5 LTBP3 ANXA5 CD83 MAGED2 RTN2 KCNAB2 PCSK1N RASSF4 RND2 ADAMTS2 MARCH2 ESYT1 ANKRD55 CLGN KCNJ14 EIF5A2 YPEL5 NRG1 GPC5 P2RX6 ECE2 SLC6A5 BAIAP3 SV2C GABRQ MTAP HCRTR1 ESRRG KIF5B WRB SLC18A2 GLRA1 CHRNB4 GLRA2 HTR2C CALM3 GFAP CCT8 DLK1 HCN2 CD59 TMEM176A SLC17A6 HMGA1 ABHD4 VDAC2 DNPEP NDUFB5 CYP27A1 CAPN1 COQ7 ENDOD1 CROT CAT LGALS8 FAM13A NDUFS1 ABHD3 B3GALT5 IMPA2	0.017995	UP
IIZUKA_LIVER_CANCER_EARLY_RECURRENCE	VIM LAPTM5 TRIM22 HLA-DRA TNFAIP3 MEF2C REL CCND2 SGK1 DDX17 PDGFRA	0.0179971	UP
EHLERS_ANEUPLOIDY_UP	FAM129A FERMT2 TMEM47 HDGFRP3 SPG20 RASIP1 PNMA1 EXTL2 CCP110 TUBGCP3 H2AFY2 NEK1 GLTSCR2 COX6A2 PTPRN2 MBNL1 RWDD2B RPL9 PHTF2 ALOX5AP EEF1A1 ID2 BCL2L2 SCAF11 CLK4 ATR CGRRF1 HAUS4 PTEN FKBP3 RABGGTB CAST FNDC3A PDGFD ALDH3A2 ERMAP	0.0180167	UP
MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3	GUCY1A3 CHODL KCNN3 GPNMB ISLR PAMR1 FXYD5 LAMA4 PDE8B CORO1A PAX5 SGCD COL1A2 IGF1 PTGFR TGFB3 RAPGEF3 TLR5 CHST3 CRABP2 PTN IDO1 CD44 FGL2 PTGS1 CDKN2C MARCH1 CNTNAP1 LYL1 KCND2 CIITA ETV2 NOL3 PHYHIP NR5A1 NPY2R TFPI2 APBB1IP OSM EXTL1 MYL7 CACNG3 LTA ADARB2 PVALB TEKT2 LECT1 KCNJ5 SULT2B1 AQP6 ALOX15B SUSD4 AQP2 NOL4 COL4A4 OPCML UCP1 TNFRSF8 DSC3 HOXB13 VRTN PDE11A DKK1 SEZ6L2 GRM3 AVPR1B KLHL1 MCHR1 PDYN GNAT1 EVPL SPINK2 NCAN PDE1C COL4A3 PTH2R PIWIL2 NPY1R EPN3 LEFTY1 SCNN1A MST1R EDN2 ABCC3 BEST2 KCNJ2 ESRP1	0.0181827	UP
CHANG_CORE_SERUM_RESPONSE_DN	ZCCHC24 APOD SERPING1 PDZRN3 CDKN1C ITPKB TNXB BHLHE40 GABBR1 BCL6 DPYSL2 DNM1 ARHGEF3 OLFML2A PRUNE2 CLIC2 C10orf10 SVEP1 TNFAIP2 SLC22A17 C1S TNFSF12 ARID5B TNFAIP8 GATM LUM TRIM22 FADS1 F10 CRTAP OSBPL8 CTSF ETV1 IRAK3 FADS2 RAB11FIP2 FYCO1 MFGE8 DAB2 PHF21A SVIL CYBRD1 MAGI2 CNTNAP1 VASH1 PNRC1 GSN REV3L GABARAPL1 MAF PIK3IP1 IL6ST C19orf66 LPIN1 HABP4 FAM198B CLCN6 LDLR KIT PBXIP1 BBC3 MEF2D SDR39U1 PLD3 SATB1 DUSP22 VAMP4 ZMAT3 ZNF83 CAMLG TIMP2 PKIG MBTD1 FABP3 KLKB1 NUPR1 CD82 CSF1 KLHL24 SNRNP70 LIPA MEGF8 ARSD CALCOCO1 ACIN1 PTPRU HDAC5 ZBTB17 C1RL RARRES3 INSIG1 MVD ISCU ARPC4 RPL37 CCNL2 WSB1 ARMCX3 IL1R1 NYNRIN NCOA3 LDB1 WDR26 CST3 SQLE ECHDC2 H2AFV TSC22D1 WBP2 SLC25A36 KLHL5 SLC35E2 JAG1 SESN1 CTNS ZNF219 RNF146 PLA2R1 IGBP1 SERF2 ATP6V0A1 CCPG1 MBP PLXNB1 WTAP NOSIP HECA APP CFB KIAA1109 LRIG2 ACSL3 ADD3 BDH2 SFTPB METTL7A ANKRD12 CYP27A1 MAN1A1 EGFR SOD2 CCNG2 ANXA11 KDM5B FDPS CDKN1A SAP30L TRANK1 PDK2 GLS FCGRT LSS IDI1 ARHGAP12 MXI1 MSMO1 CD46 SEPT11 TRIM25 POR SLPI TFDP2 SCD HMGCS1 SQRDL ACY1	0.0181923	UP
SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	ACTG2 FLNA ANGPTL2 FLNC WASF1 MYLK FSCN1 PAK3 GDI1 LIMK1 ROCK1 AKT1 PAK2 RHO FSCN2 RPS4X PFN1 PFN2 VASP FSCN3 PAK6 ACTR3 MYH2 ACTG1 GDI2 PAK4 ACTR2 CFL1 CDC42 ROCK2 PAK1 WASL	0.0187699	UP
PID_IL12_STAT4_PATHWAY	FOS TGFB1 JUN HLA-DRA CD86 CD4 HLA-DRB1 CD3D CD3E CD247 CD28 IL2RA ETV5 PPP3CB IL18R1 IL13 STAT4 PRF1 PPP3R1 CREBBP PIAS2 CD80 TBX21 STAT3 MAPK8 IL18RAP IL2 CD3G PPP3CA IFNG IRF1 MAPK9 IL18	0.0187972	UP
LEIN_ASTROCYTE_MARKERS	ATP1A2 CLU SPARCL1 S1PR1 ITGAM C1QA SPARC CLDN5 MFGE8 GJA1 PLA2G7 STAB1 GSN ALDOC APOE SELPLG SEPT4 MATN4 DIP2A GLDC GLUL BCAN MAGI1 EMX2 CST3 AQP4 CD63 SLC6A20 NCAN GFAP ITGB5 GPR37L1 ID3 MLPH PRDX6 DBI	0.0188506	UP
TSENG_IRS1_TARGETS_DN	FABP4 AOC3 THBD SGCE CRIP2 ITPR1 DKK3 DENND5A TNXB CAPN6 NRP1 LIMCH1 HLX COL6A3 SPARCL1 COL4A1 ADARB1 ACTC1 SH3BGR TMEM45A COL4A2 COL6A1 ZFHX3 PPL RAMP2 EPHB6 GGT5 FMO1 LIFR DAB2 B3GALNT1 SEMA3E CD40 CDKN2C ZNF32 LPAR1 IGFBP4 GJA1 TGFBI TNNT2 IL6ST COL3A1 HGF CIRBP NFYB RAB3B FAM50B NMB RASA4 PAX3 PML SNAI2 GSTT1 TNNT3 SNTB1 MMP14 MYL4 ZFR2 SIX1 CCDC88A MYLPF MYL1 H6PD ADAM23 ITIH2 TMUB2 IL1R1 LONP2 TNNC1 SMAD6 ZNF821 RBM10 CST3 ART3 THRA ZNF394 TAPBP CASP2 TSC22D1 EFNB1 DIAPH1 SMS TLE3 SESN1 TNNI1 CD63 SIRT3 POPDC3 TSPAN31 RAD52 HSBP1 EPHX1 GPR37L1 CAND1 C21orf33 GNPTAB KNG1 FAH CTDSP2 GLRX ADM GAS2 CAPG CARHSP1 FTH1 ESRRA VSNL1 EIF4E2 RAB9A LITAF RAB14 GHITM PHKA2 MGST3 CCDC6 MAOA HSD17B11 TRAF3IP2 HCCS PIP5K1B TSPAN6 ENPP1 RSAD2	0.0188545	UP
OKAMOTO_LIVER_CANCER_MULTICENTRIC_OCCURRENCE_UP	SRPX LGALS1 SLC15A3 SPON2 ITGB2 PTPRC HLA-DQA1 MNDA CD14 CALCOCO1 EIF2S3 MPP1 CDC5L SQLE SNRPG PUF60 IGBP1 SLC12A7 SLK AHCYL1 RPA3 VDAC2 RALB LITAF	0.0188771	UP
HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_UP	MYH11 MS4A1 GIMAP4 VEGFB LAT2 HLA-DQB1 HLA-DQA1 LTB ABHD14A NEDD4 CTSH NCF4 HLA-DMA PRPS1 CD83 ICAM1 CD22 HLA-DRB1 SLC2A3 CFP CXCR5 SEMA4D CD40 CD74 ISYNA1 MYOG FES SIPA1 MEF2C FCER2 GGA2 PTPN12 CCND2 EHD1 PRTN3 LHB MAPK8IP3 IFI30 CNR2 HPCAL1 CD36 APOC3 HOXC5 MYH7 XPO1 LY6D PSAT1 RHOD FLII EEF1G MYBBP1A RBMS2 SERBP1 HMBS MFHAS1 SDC4 DAD1 HES1 PEPD ATP5G1 MECOM LEFTY1 SERPINB1 SUCLG2 ACY1	0.0188928	UP
ZHAN_MULTIPLE_MYELOMA_MF_UP	TUBB2B GPM6B SMARCA1 CXCL12 ARHGAP6 SPP1 DPYSL2 NUAK1 RNASE6 MCTP1 DOCK4 CX3CR1 ARID5A CEBPD LCP2 RASSF4 SYNDIG1 NTRK2 ITGB7 MFAP2 TYMP FAM174B DEFB4A TLR4 CCDC86 NMU TMPRSS15 ARPC1B GREB1 PEBP1 ABLIM1 ATP13A2 PYGB SLC25A20 CDH1 APOBEC3A SHMT1 AGMAT	0.0189954	UP
KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN	CTH ERBB3 CEBPG GSR AKAP9 CDH1 UPP1 CCNB1 CDA CANT1 CCNB2 PNP EBP MET TNFSF10 MAP3K9 MGST2 GSTK1 SOS2 CDKN2B CCNE2 RPS6KA5 CTPS2 CDK5 SOS1 MAPK14 CDK1 IFRD1 CDC42 RTP4 TK1 BIRC5 HDAC1 AK4 AURKB IRAK1 RRM1 TOP1 POLQ PDGFA MDM4 RAD54B ATF2 PMVK VTN DTYMK ECHDC2 NME1 CALM1 FEN1 HSP90AA1 IFRD2 CDK2 IRF7 MTAP TRADD DNMT1 OGG1 MPG BIRC3 DDIT3 CDC25A IL1B PLAU NFKBIA TNFRSF12A LEF1 ATM MYC MAP3K14 TNFSF12	0.0191383	DOWN
BIOCARTA_VIP_PATHWAY	VIP EGR3 EGR2 PRKAR2B NFATC1 PPP3CC MYC PLCG1 PRKACG NFKBIA PPP3CB PRKAR1B PRKAR1A RELA VIPR2 MAP3K1 CALM1 CALM3 CALM2 PPP3CA GNAQ PRKAR2A NFKB1 PRKACB CHUK	0.0191605	UP
REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING	NRAS MAPK1 KRAS EGFR EGF SOS1 CDK1 MAPK3 MAP2K2 YWHAB GRB2 MAP2K1 RAF1 SHC1 HRAS	0.0191691	DOWN
DELPUECH_FOXO3_TARGETS_DN	PITX2 CEBPG PRC1 NEK2 PCK2 AURKA ZWINT MKI67 FOXM1 CENPF MB EFNB2 NUSAP1 KIF22 SMC4 UBE2C H1F0 VEGFA GADD45A TIAL1 LARS SLC7A1 PYCR1 DTYMK APEX1 IMPDH2 EXOSC8 PFN2 SHMT2 IARS HAX1 SLC1A4 NUPR1 XPOT AARS C6orf48 MTHFD2 AREG CDC42EP3	0.0191994	DOWN
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP	PTGS2 NR4A2 GEM DMD FERMT2 TIMP3 DNAJC6 RBPMS DLC1 ZEB1 MEIS1 CAV1 SPOCK1 CDKN1C CFD FN1 CADM1 HBB ANGPT1 HOPX TYRP1 OAS2 TMEM45A LY6E DBN1 PRKAR2B IFI44L TPSB2 IFI44 GATM PALLD TRIM9 SERPINE2 CCR6 GPR18 UST CFP HERC5 LSP1 CDC42EP3 IDO1 IFI6 MX2 TNFAIP6 ATP10A DUSP4 TOX SLC27A6 BATF3 SP110 TPSAB1 MFAP3L AFF3 FCER2 FGF18 FLT3 KIT SLC6A13 ITGB7 SCN2A MYCT1 IGLL1 IFIT1 TM4SF1 HBD MX1 CFI ISG15 CD1D GMPR ANGPT2 CALB1 HOXA3 RARRES3 GBP1 IRF7 HOXB3 ADCYAP1 STS ZNF93 CD38 IFITM1 SLC8A1 XAF1 LILRA2 CXCL10 LILRA5 USP18 RAB27B DDX58 TGM5 OAS3 ADRB1 EIF2AK2 STAT1 CKB CHRNA6 SPINK2 IFIT3 HS3ST3B1 FAM134B LGALS2 ABLIM1 ALDH1A1 MED18 DHRS3 THBS1 RTP4 ZNF711 ARG2 ARL4A AUTS2 MCM4 IFIH1 STXBP6 IFIT2 SOX4 ARHGAP5 IL15 REN FLNB LGALS3BP HOXA7 SAMD9 HOXA5 TFDP2 EPCAM APOL6 IFI27 HMGCS1 KRT18 INPP4B HPGD DDX60 CDH1 EGLN3 GALNT12 GNAI1 DHRS9 OAS1 HOXA9 OASL DEFB1 RSAD2	0.0192254	UP
KEGG_PRIMARY_IMMUNODEFICIENCY	PTPRC CD19 CD79A AICDA LCK TNFRSF13B BTK IL7R ICOS CD4 CD3D CD3E ADA CD40 ZAP70 CIITA RFX5 CD8A IGLL1 CD40LG AIRE DCLRE1C IL2RG CD8B RFXAP IKBKG RAG1 JAK3 RAG2 TAP1 TAP2 BLNK RFXANK UNG	0.0193339	UP
REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	SYT1 STXBP1 SNAP25 SYN1 VAMP2 RIMS1 RAB3A SYN2 SYN3 STX1A SLC18A2	0.019359	UP
SINGH_NFE2L2_TARGETS	NQO1 GSTM4 GCLM GSR HMOX1 TXN ME1 TXNRD1 GCLC PRDX1 G6PD ABCC2 GRK6 ABCC1	0.0195178	DOWN
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP	PTGS2 RTN1 VNN1 GUCY1A3 CH25H PTGER3 RBPMS CD69 MEIS1 CAV1 SERPING1 CDKN1C PCDH9 PBX3 ANGPT1 HLX HOPX ARHGEF3 EVI2A CTSG PTPN13 OAS2 RNASE6 IFI16 LY6E CCL18 IFI44L ARID5B BST2 IFI44 CLEC2B TRIM9 ARHGAP22 TTC28 TRIM22 ERG HERC5 IDO1 IFI6 MX2 TOX PTGS1 BAMBI KIF13A IGFBP4 SLC27A6 SP110 CLSTN3 C19orf66 FGF18 SCN2A MYCT1 IFIT1 CRHBP AHR CELA2B MX1 ISG15 GMPR PLA2G4A ANGPT2 MYCN CYP1A1 STAT2 HOXA3 RHOBTB1 DST GBP1 IRF7 HOXB3 TCN1 FRAS1 ITGB8 IFITM1 XAF1 TXK HEY1 IFIT5 CXCL10 OFD1 IRF9 USP18 CRISP3 SCN9A RAB27B DDX58 OAS3 ADRB1 EIF2AK2 STAT1 SPINK2 HERC6 PDE1C IFIT3 GALNT2 SLC12A8 PRSS23 ALDH1A1 IFI35 NFAT5 PARP12 S100A10 AUTS2 PTPRD LOX IFIH1 CRISP2 RPS6KA5 DMXL2 IFIT2 SOX4 ATP1B1 REN LGALS3BP BMP2K HOXA6 MECOM HOXA7 MLLT3 KIAA0513 TRIM25 SAMD9 HOXA5 MVP QPRT IFI27 ERMAP INPP4B DDX60 PHACTR4 HIST1H2AC KLF5 OAS1 HOXA9 OASL MAP7 ACSM3 RSAD2	0.0196726	UP
REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE	SYT1 STXBP1 SNAP25 VAMP2 RIMS1 RAB3A STX1A SLC18A3 CHAT SLC5A7	0.0197127	UP
MORI_LARGE_PRE_BII_LYMPHOCYTE_UP	E2F8 HMMR PRC1 CENPA TTK CCNA2 AURKA MELK HMGB3 ENPEP CCNB1 TOP2A DTL TXN CDC20 CCNB2 LGALS9 MKI67 IDE CKS1B SMC2 CDKN3 CENPE KIF23 LMNB1 CDKN1A TMPO RACGAP1 ASF1B KIF22 MCM2 CDK1 SMC4 NCAPH PRDX4 KPNA2 SLC12A3 HNRNPAB RRM1 H2AFX RAD21 CBX1 PPIA CALM2 RRM2 LIG1 BUB3 MCM7 CDCA3 XRCC6 FANCC H2AFV SLBP RBBP4 SMARCA4 ANAPC5 TUBB4B HMGN2 PPP2R5C HMGB1 PSMC1 MCM6 RANGAP1 UBE2S RAN SMARCC1 MCM5 DUT STMN1 MCM3 NUCKS1 MYBL2 IGLL1 ZNF358 TUBB ANP32E CDKN2C SLC29A1 LGALS1 TUBA1A RAMP1	0.0197682	DOWN
WANG_BARRETTS_ESOPHAGUS_UP	REG1A OLFM4 FMO5 AKR1C3 HSD17B2 CCL15 CA2 FCGBP GPA33 ACADS MUC5B SLC12A2 ABHD2 LGALS9 ALDOB FABP1 FUCA1 VIPR1 RALB POLD4 PCSK7 KDELR2 ITGB4 GLRX DDX19B PXN TCN2 DAZ4 ATP2A3 S100P TMSB4X ITGA3 PRSS22 ITPK1 PFN1 PLEC TM4SF4 ISG20 CHGA WNT4 DMWD LYN IGLL1 CCL14 MSLN NR2F2 COL6A1 RGS2 CLU	0.0197925	DOWN
REACTOME_G2_M_CHECKPOINTS	RFC5 CDC25C CCNB1 ORC2 CHEK1 HUS1 CCNB2 CDC6 CDC7 ORC5 ORC4 MCM4 ORC1 MCM2 CDK1 RFC2 CHEK2 RPA3 RFC3 ATR RAD17 ORC6 RAD1 MCM7 DBF4 RAD9A MCM10 RPA1 CDC45 ORC3 WEE1 CDK2 MCM6 RPA2 MCM5 MCM3 CDC25A RFC4 ATM	0.0198756	DOWN
KEGG_LIMONENE_AND_PINENE_DEGRADATION	EHHADH ALDH7A1 HADHA ECHS1 ALDH3A2 YOD1 ALDH2 ALDH9A1 ALDH1B1 NAT6	0.0198917	DOWN
HORTON_SREBF_TARGETS	CYP51A1 ELOVL6 HMGCS1 AACS ME1 IDI1 LSS FDFT1 FDPS DHCR7 RDH11 FASN PMVK TM7SF2 ACACA SQLE ACLY INSIG1 HSD17B7 ALDOC LDLR	0.0198967	DOWN
BIOCARTA_ETC_PATHWAY	GPD2 SDHB SDHC SDHD SDHA UQCRC1 CYCS ATP5A1 NDUFA1 SLC25A6 SLC25A4	0.0199061	DOWN
TURASHVILI_BREAST_CARCINOMA_DUCTAL_VS_LOBULAR_UP	RAB11FIP1 LAMP2 CDH1 DTL EPB41L3 CKS2 HIST1H3B S100P AHCTF1 CPB1 TTC3 MEX3C STK4 SLC1A2 OSBPL10 B3GALNT1	0.0199345	DOWN
KEGG_HUNTINGTONS_DISEASE	PPARG PPARGC1A RCOR1 CASP3 PLCB4 NDUFS1 APAF1 SDHB SDHC VDAC1 COX5A SDHD NDUFS2 NDUFB7 ATP5G3 CYC1 NDUFA10 SLC25A5 SP1 NDUFA9 NDUFS4 SDHA NDUFB3 ATP5D NDUFS3 ATP5B NDUFS7 UQCRFS1 UQCRC1 UQCRC2 ATP5G1 CYCS COX5B NDUFV1 NDUFA8 NDUFB6 NDUFC2 NDUFA6 ATP5F1 CLTB UQCRQ CREB3L1 DCTN4 PPID IFT57 SOD2 NDUFC1 BAX COX6A1 NDUFB5 COX7B ATP5A1 ATP5C1 NDUFB2 COX7A2 NDUFA5 NDUFA7 UQCR10 TBPL1 CASP8 NDUFAB1 COX8A SOD1 COX6B1 NDUFS6 NDUFA2 UQCR11 VDAC2 COX6C ATP5O ATP5J POLR2E HDAC1 ATP5H NDUFA1 POLR2H NDUFV2 EP300 TFAM AP2B1 UQCRH CLTC COX4I1 NDUFB4 COX7C NDUFB1 CREB3 GNAQ TAF4 NDUFS5 TBP DNAL4 SLC25A6 NDUFB8 POLR2J POLR2C NDUFS8 CLTA AP2A2 POLR2D CASP9 NDUFA3 AP2S1 POLR2F HTT CREB1 COX7A2L HDAC2 DCTN2 POLR2L VDAC3 AP2M1 PLCB3 ATP5G2 POLR2K POLR2B DNAH2 UQCRB ATP5E POLR2A POLR2G GRIN2B HAP1 NDUFA4 TP53 UCP1 GPX1 CREBBP SLC25A4 SLC25A31 GRIN1 POLR2I NRF1 DCTN1 GRM5 REST CLTCL1 COX6A2 DNAI1 DLG4 PLCB2 TAF4B DNAI2 CREB3L2 DNALI1 HIP1 BDNF BBC3 POLR2J3 DNAH3 NDUFA4L2 CREB5 TGM2 PLCB1 ITPR1 COX7A1	0.0199861	DOWN
REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI	PIGL PIGO PIGV PIGG SEMA6D PIGN PIGA PIGB PIGH PIGF DPM2 PIGP PIGC PIGQ	0.0200656	DOWN
RHODES_UNDIFFERENTIATED_CANCER	GGH CEBPG GCLM MAD2L1 SLC16A1 CENPA CCNA2 MELK CCNB1 DLGAP5 TOP2A CDC20 FOXM1 CKS2 CDC6 EZH2 CKS1B CDKN3 KIF23 KIF2C NCAPD2 KIAA0101 GPSM2 MCM2 CDK1 KIF14 BIRC5 NCAPH PRDX4 RPA3 UBE2C DPM1 TAP1 KPNA2 ILF2 PCNA H2AFX SEC61B PSMB7 RAD21 PSMD2 PSMD14 TMSB10 EIF2S2 CCT6A HMGB2 NME1 POLR2K H2AFZ SSBP1 ADRM1 YBX1 MCM6 UBE2S GAS6 GARS CXCL9 TRIP13 MCM3 IFI30 NUDT1 MYBL2 RFC4 TUBB MTHFD2 TUBB4A SLC7A5 COL1A2	0.0200757	DOWN
WESTON_VEGFA_TARGETS	MGP GEM CCL2 NNMT SGCE NR4A1 RHOB CXCR4 PDE4B TIE1 EFEMP1 ELN CFHR1 GJA4 VCAM1 COL6A3 HTR2B ISL1 RGS5 ROR2 THY1 LMO2 COL1A2 HCLS1 VIM ICAM2 C1S VWF COL6A1 ZFHX3 BGN FAP CD34 FHL3 CXCL1 COL5A1 MMP2 ART4 UBD IGFBP3 PIM1 BDNF TFPI2 GSTT1 PGF FOXO1 PVALB ANGPT2 KDR OXTR SHC3 MMP3 MPHOSPH10 VCAN RANGAP1 ADD2 ESR1 NID2 MMP10 SLC6A8 BMP4 CCL7 KRT7 RBX1 BMP6 BCKDHA TRIM23 HEXA DYNLL1 ANKRD1 IL32 NDUFA1 SDC4 SULT1E1 SP3 SAT1 AQP7 GALNT1 PRKCI FUCA1 UNG CD9 PRKAB1 TNFSF10 PNP SEMA5A FBP1 IFI27 PIR GCHFR KRT18 POSTN MMP1 RALA CEACAM1 MEST HSD11B2 FGFBP1 F2RL1 MRPL19 GGH ADORA2B	0.0201935	UP
KEGG_ALLOGRAFT_REJECTION	HLA-DOB HLA-DQB1 HLA-DQA1 HLA-DRA HLA-DPA1 HLA-DMA HLA-DRB5 CD86 HLA-DRB1 HLA-DRB4 HLA-DMB HLA-DPB1 CD40 CD28 CD40LG IL10 IL12A FASLG PRF1 HLA-DOA IL12B IL5 CD80 GZMB IL2 IL4 HLA-E IFNG HLA-C HLA-G HLA-B HLA-A HLA-F TNF FAS	0.0205752	UP
ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP	IGFBP5 CXCL12 DCN BCL6 JUN FGFR1 PDGFRB A2M CCND1 MAPK12 CD44 CDC25B RUNX2 IGFBP3 APOE BTRC CD36 RARA TNFRSF1A RB1 CDKN1B NFKB1 APP FAS SERPINA1 HMOX1	0.0206813	UP
SMID_BREAST_CANCER_RELAPSE_IN_LUNG_DN	ASPN LMOD1 FABP4 ADIPOQ ADH1B COL14A1 DPT CILP ITGA7 PPP1R1A IGF1 ABCA8 CLDN5 RAPGEF3 TBC1D19 SFRP4 DUSP6 LRRN3 TFAP2B SCGB1D2 TIMP4 DNALI1 COMP PRODH SCGB2A2 CXCL14 TTC12 PDCD4 SCUBE2 TFF1 SLC1A1 TOX3 SCGB2A1 NAT1 HMGCS2 LRRC31	0.0207227	UP
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN	PEG3 TAC1 ADIPOQ GPM6B PEG10 CAP2 SFRP1 PPP1R1A ITIH5 LPL CAPN6 ZDHHC11 OLFM1 NEFH RBP4 CRABP1 TRO NNAT RET RIMBP2 NDN SOX11 NPTX2 ISYNA1 CRLF1 APBA2 COL9A3 FGF18 NTRK2 PRAME ACACB GPD1 MDFI SIM1 NELL1 EFNB3 COL2A1 B3GAT1 CACNA1G CUX2 SIX1 RAC3 GPC4 ECHDC3 CITED1 HIP1R NFIB EMX2 RHOD COL4A5 SHANK2 SEZ6L2 TLE1 TLE2 LHX2 DLK1 LRRN2 WIF1 SEMA6A FGFR3 ITM2C RIPK4 ALDH5A1 CTAG2 FGFR2 IGFBP2 HSD11B2 EDN3 EPHX2 EPB41L4B KBTBD11 TOX3	0.020723	UP
REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	C3 SELL VCAM1 FCGR2B CD81 ITGB2 CD19 ICAM2 TYROBP ITGAL ICAM1 CD34 CD3D CD3E CD40 CD247 ICAM4 LILRB2 CD8A KIR2DS2 CRTAM ITGB7 CD96 CD40LG KLRK1 CD226 LILRA1 LILRB1 LILRB5 CD8B KIR3DL1 ULBP2 KIR2DL1 LILRB4 ULBP1 KIR2DS1 KIR3DL2 ITGB1 IFITM1 ICAM3 KIR2DL2 PVR KLRD1 B2M KIR2DL4 CD3G HLA-C HLA-G HLA-B KIR2DL3 HLA-A HLA-F CD160 CDH1 CXADR	0.020724	UP
HOELZEL_NF1_TARGETS_UP	SCG2 AHNAK2 ANK2 GUCY1A3 HSPB8 PDLIM3 GAP43 DCLK1 PCDH7 RGS13 CAPN6 SEPT6 RAB31 SPARCL1 RELN NRXN1 PLS3 CPEB1 IFI16 GRIK2 RGS16 GDF15 PCDH17 HS3ST3A1 DRAM1 CPVL ODAM NACC2 CEBPB DUSP4 MGAT4C EEF1A2 MAP2 SLC27A6 SERPINE1 PDZK1 PAPPA HGF PXDN PHLDA1 UTS2 PLK2 B4GALT6 NRG1 DCBLD2 NTS HBE1 CHRM3 ATXN1 HSPA4L PLEKHA5 GNAS IGSF1 GPR22 HEY1 SLC18A1 ACVRL1 TRIM44 HS2ST1 STAMBPL1 S100A2 NRCAM CLSTN2 SCN9A OSBPL3 GAD1 RND3 HS3ST3B1 FAM46A PDGFA FAM134B FAM114A1 ERGIC2 THSD4 STK17B SEL1L3 CLCN5 PDLIM5 NRIP1 S100A10 PHACTR2 CYB561 ARHGAP26 FAS GLS NUP62CL ENDOD1 LGALS3 PHLDA2 MOSPD1 SPATS2L DEPTOR RPS6KA3 MET EPS8 TRAF3IP2 PRSS12 STEAP3 ITGA2 UPP1 TNIK NXT2 EDN3 XK	0.020957	UP
NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_UP	GAS1 COLEC12 COL6A3 PCOLCE COL1A2 BMP7 PRAME COL9A2 FOXD1 DLX5 ADAM12 ENC1 ADNP SOX4	0.0209833	UP
CHEN_ETV5_TARGETS_SERTOLI	THBD CXCL12 ANGPTL2 GPNMB FCGR2B CD53 IL6 C1QB PLEK CLEC7A ARSB FCGR2A ARID3B CD36 MMP12 CCL7 CXCL6 GCG	0.0212594	UP
REACTOME_TELOMERE_MAINTENANCE	HIST1H2BC HIST1H4H HIST1H2AE HIST1H2BH RFC5 HIST1H2AC HIST1H2BD HIST1H2BG HIST1H2BE HIST1H2BI HIST1H2BF PRIM2 POLD4 HIST1H2AJ HIST1H2BM HIST1H4K HIST1H4B RFC2 HIST1H2BK HIST1H4J HIST1H4D HIST1H2AD RPA3 HIST2H2AA3 HIST1H4F POLE2 RFC3 PCNA H2AFX RUVBL2 HIST1H4C HIST1H2BO HIST1H4L TERF2 POLA1 POLD2 HIST2H4A HIST1H4A LIG1 POLD3 HIST2H2BE DKC1 NHP2 HIST1H2BB DNA2 FEN1 TERF1 HIST1H2BJ H2AFZ WRAP53 HIST1H4E RPA1 PRIM1 HIST1H4I TERT RPA2 HIST1H2AB TINF2 POLE POLD1 POT1 RUVBL1 HIST3H3 HIST1H2BN HIST1H2BL RFC4 POLA2 ACD TERF2IP	0.0212858	DOWN
KEGG_GRAFT_VERSUS_HOST_DISEASE	HLA-DOB HLA-DQB1 HLA-DQA1 HLA-DRA HLA-DPA1 HLA-DMA HLA-DRB5 CD86 IL6 HLA-DRB1 HLA-DRB4 HLA-DMB HLA-DPB1 CD28 IL1B KIR3DL1 KIR2DL1 FASLG PRF1 HLA-DOA KIR2DL5A KIR3DL2 KIR2DL2 CD80 GZMB KLRD1 IL2 IL1A HLA-E IFNG HLA-C HLA-G HLA-B KIR2DL3 HLA-A HLA-F TNF FAS	0.0214459	UP
LEE_LIVER_CANCER_E2F1_UP	FABP4 ACTG2 KIAA1462 PALMD BCL2A1 RHOB ANXA1 LEPR LPL COL5A2 CPE COL1A1 SPON2 SPARC LY6E IFI44 ANXA5 PPL MFGE8 SHCBP1 CD74 GPC3 NUCB2 UAP1L1 MCL1 FMO3 SPTAN1 CASP4 KRT23 HOXC6 TM4SF4 RAD51B RPL36 CYP39A1 MMP12 GSTM2 CXCL10 USP18 CTSE ACTG1 CD63 GSTM1 TAGLN2 ETS2 IGFBP1 PLAT TMEM176B ANXA2 NT5E DYNLT1 IFIT2 PLSCR1 LCN2 CSTB CTSS KRT8 XDH CXADR TFF3 SPINK1 DEFB1 GGH	0.0215029	UP
ALONSO_METASTASIS_NEURAL_UP	PMP22 MAL MITF PTPRZ1 CHN1 KIT SETX ENC1 MAGEA6 ENOPH1 SDCBP CD63 PDGFRA APLP2 S100A10 EMP1	0.0215286	UP
ZHAN_MULTIPLE_MYELOMA_CD2_UP	PDZRN4 SDC2 BEND5 ITPKB RGS13 VPREB3 MS4A1 PAX5 CNR1 CD79A LAMA2 CD27 PNOC TRAF5 B3GALNT1 TNFSF8 DUSP22 SPAG4 RNGTT NAGK SLC8A1 PRDM5 RCBTB2 RERE SRC PLXNB2 APLP2 TGIF1 NF1 MARCKS CNPPD1 PTPRJ DYRK2 DHTKD1 PHLPP2 SORT1	0.0215345	UP
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN	FCGR2B S100A8 ENTPD1 IL7R MAFB PPBP CD163 CLEC10A TGFBI HGF ETS1 S100A9 ALOX5 OSM ATP10D HBE1 GLUL TEX15 FCGR2C PRG3 RAP1A ALB LIF CCL7 CXCL5 RAPGEF5	0.0215774	UP
AKL_HTLV1_INFECTION_DN	PTGS2 MEIS2 FRY ANXA1 STAP1 HOPX JUN PRUNE2 FYN HTR3A IGFBP7 PECAM1 TMEM45A ATP8A2 PKIA GPR171 CD86 GPR65 CPVL DUSP6 MDFIC DUSP4 KHDRBS3 REV3L MEF2C ENPP2 CD96 YPEL5 FAM3C GNLY PNISR ITGB1 SERINC1 TTN MINA GZMB RWDD1 LANCL1 TSPYL1 PMCH CD3G SERP1 PTPN2 UBE2J1 SDF4 ATP5L COL4A6 CEP192 DNAJB6 RPIA CDK19 VAPA UFL1 PDE4DIP CCNC GZMA DNAJC15 TCTN3 CTSA MAOA DENND1B CDH1 IL17RB AKAP9 PTPN3	0.0215843	UP
NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_DN	SYNM BCHE GUCY1A3 SFRP1 RBPMS SCRG1 BHMT2 FGL2 PRKCQ NUPR1 AMPD3 PLAT METTL7A LGALS3BP CASP1 TNFSF10 CCDC68 CA2	0.0215937	UP
BIOCARTA_INTEGRIN_PATHWAY	TNS1 CAV1 PPP1R12B ITGA1 JUN FYN ACTN1 TLN1 ZYX ACTA1 VCL ACTN2 ACTN3 ROCK1 ITGB1 CSK RAPGEF1 RAP1A HRAS MAPK8 PTK2 SHC1 RAF1 MAP2K1 GRB2 RHOA PXN SRC BCR MAP2K2 CAPNS1 MAPK3 CRKL SOS1 CAPN1 MAPK1	0.0216236	UP
KEGG_SELENOAMINO_ACID_METABOLISM	CTH AHCYL2 METTL2B PAPSS2 CBS AHCY SEPHS2 LCMT1 GGT1 AHCYL1 TRMT11 MAT2B SEPHS1 HEMK1 MAT1A WBSCR22 MAT2A LCMT2 MARS SCLY PAPSS1 GGT5	0.0216515	DOWN
SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP	EGR1 TUBB6 CCL2 EGR2 AMOTL2 BHLHE40 EREG TUBB2A IER2 DUSP6 SOCS3 PTGES SLC25A28 PPAN PHLDA1 FOSL1 NOP56 BYSL CDR2 MAK16 CCL7 THBS1 SPSB1 SLC2A1 SPRED2 SYNJ2 B3GNT2 HMOX1 HMGCR	0.0219786	UP
WANG_TNF_TARGETS	NOTCH3 VCAM1 JUN GDF15 SELP IL6 SELE TNFAIP3 MADCAM1 CD6 NFKBIA CSF3 TRAF1 LIMK1 GSTT1 CSF2 MMP3 MMP13 CD68 BCL2L10 KRT35 YY1	0.0221448	UP
BIOCARTA_CSK_PATHWAY	PTPRC PRKAR2B LCK HLA-DRA CD4 HLA-DRB1 CD3D CD3E CD247 ZAP70 PRKACG PRKAR1B PRKAR1A GNAS CREBBP CSK GNB1 ADCY1 CD3G GNGT1 PRKAR2A PRKACB	0.0221849	UP
FERRARI_RESPONSE_TO_FENRETINIDE_UP	PTGS2 ATF3 KLF7 BHLHE40 C10orf10 CXCL2 DDIT4 SLC7A5 SELE ST3GAL1 CCL20 DDIT3 TRIM33 CXCL3 HERPUD1 DHRS3 IRF1 NRIP1 SEMA3C BMP2 GPRC5A	0.0223223	UP
LI_WILMS_TUMOR	CHRDL1 MN1 WASF3 FZD7 MEOX1 SALL2 NNAT INHBB APOC1 GLI3 CRABP2 PRAME LYPD1 COL13A1 ETV4 COL2A1 SIX1 FOXG1 EYA1 CHST1 HOXA11 PAX2 HAS2 HMGA2 HOXA9	0.0223307	UP
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP	PTGS2 NR4A2 SDPR DNAJC6 MYH10 RBPMS DLC1 MEIS1 SPOCK1 PCDH9 CCR7 HBB ANGPT1 HOPX TUBB2A LTBP3 CTSG TYRP1 OAS2 LY6E PRKAR2B IFI44L TPSB2 IFI44 PALLD CLEC2B GDF15 TTC28 DDIT4 FOXC1 APOC1 GPR18 HERC5 IDO1 IFI6 MX2 TNFAIP6 CHST2 HIC1 IGFBP4 ISYNA1 SLC27A6 GJA1 TPSAB1 MEF2C ENPP2 TAL1 FGF18 FLT3 BDNF SLC6A13 KLF1 MYCT1 IGLL1 IFIT1 HBD MX1 ISG15 MYCN CALB1 HOXA3 REXO2 RHOBTB1 NMU GBP1 IRF7 HOXB3 ADCYAP1 RHAG IFITM1 XAF1 MTSS1 SPTA1 IFIT5 GZMB USP18 CRISP3 RAB27B DDX58 TGM5 OAS3 TSC22D1 ADRB1 EIF2AK2 STAT1 GAD1 SPINK2 HERC6 IFIT3 HS3ST3B1 SLC12A8 PRSS23 ALDH1A1 DHRS3 THBS1 F2R FHL2 AUTS2 IFIH1 RPS6KA5 IFIT2 SOX4 REN LGALS3BP FAT1 MECOM HOXA7 GCH1 HOXA5 ABCB1 LXN IFI27 KRT18 DDX60 CDH1 ATP7B OAS1 HOXA9 AMMECR1 MAP7 DEFB1 RSAD2	0.022339	UP
GOUYER_TATI_TARGETS_DN	TAGLN IGF2 FN1 MCAM S100A4 CSPG4 MAPK12 A4GALT PTP4A3 BMP7 SNCG TIMP4 HPN FABP5 IGFBP2	0.0223391	UP
NOJIMA_SFRP2_TARGETS_UP	CTGF CLU NR4A3 PPP1R15A JUN TNFRSF9 HSPA6 CD40 TNFAIP3 WARS INHBE BAG3 TRIB3 CSF1 IL24 BTG1 TNN IKBKG TP53AIP1 GADD45B CLK1 HSPA5 TNFRSF10D HSPA1A CIDEC VHL GADD45A HSPA9 MXD1	0.0223417	UP
KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE	CSGALNACT1 CHST15 CHST11 CSGALNACT2 DSE UST CHST3 CHST12 CHSY1 CHST7 XYLT2 CHPF B3GAT3 B3GAT1 B4GALT7 CHPF2 XYLT1	0.0223589	UP
LI_CISPLATIN_RESISTANCE_UP	PEG10 EPHA3 CYP1B1 THSD7A KYNU TWIST1 ITM2A ZBTB20 CDH2 ANO3 GJA1 TFPI2 SMARCA2 COL11A1 CKLF IGF1R NEBL HAPLN1 TMEM2 EGLN3	0.0223897	UP
CORRE_MULTIPLE_MYELOMA_UP	SCG2 PTGIS DMD TFPI CSGALNACT1 NRXN3 SLC24A3 SAMSN1 MAFF CD200 LMO2 RGS4 GDF15 PDGFRL SLC7A5 ALDH1A3 ANGPTL4 AREG SERPINE1 ABCA6 ITIH4 MYCT1 CLDN11 COL13A1 IL1B SEPT9 CLCN4 EIF4EBP1 ATXN1 CDKN2A TLR4 PDE10A ADAMTS12 ADAM23 GCKR FAM155A SERPINB2 EXOC6B PSPH ITGA3 USP53 TNFSF4 ANKRD1 AADAC PLAT DPP4 GLRX SLC25A23 ITGA2 HGD GATA6 MYO1D PTPRR	0.0224286	UP
OSADA_ASCL1_TARGETS_DN	BCL2A1 AXL CYP1B1 DUSP1 IGFBP6 DKK3 RASSF2 FGFR1 SOCS3 CD44 TGFBI AHNAK WNT7B NRG1 BIRC3 CRIM1 DKK1 CYP24A1 SEMA3C CDH1 KLF5	0.0224309	UP
SASAKI_TARGETS_OF_TP73_AND_TP63	CYR61 SERPINF1 JAG2 DUSP7 ITGB1 IL4R JAG1 MT2A MT1X MT1H	0.0224544	UP
MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP	MGP DMD SULF1 FHL1 MYBL1 ATRNL1 AREG GJA1 PDZK1 CYP26B1 PGR ABCA12 KLK11 GREB1 ELOVL2 METTL7A NPY1R TFF1 AGR2	0.0224629	UP
FINAK_BREAST_CANCER_SDPP_SIGNATURE	OGN SPP1 RAI2 CD48 LCP1 RUNX3 CD52 GIMAP5 ITGBL1 PLEK CD247 CD8A SNTG2 F2RL2 HRASLS VGLL1 CXCL14 FRZB ADM GZMA HOXA10 ADRA2A	0.022525	UP
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	CLU MMRN1 RHOB SERPING1 CFD FN1 VEGFC F8 AKT3 F13A1 TGFB1 COL1A1 GNG11 FYN COL1A2 SPARC PECAM1 GNB5 VEGFB ACTN1 VWF DGKB PRKCH RASGRP1 TIMP1 GNG3 TLN1 LCK TGFB3 PROS1 PDGFB GNAI2 RAPGEF3 SRGN PRKCB SELP RAC2 RASGRP2 LCP2 CALU A2M PLCG2 PPBP PLEK PIK3CG GP1BB VAV1 PRKCQ SERPINE1 GNA12 FCER1G LEFTY2 LAT HRG DGKG GP1BA FGB HABP4 GNG7 ARRB2 PIK3R3 HGF GNA15 VCL PRKCA LYN ITPR2 SCG3 APBB1IP ACTN2 PRKCG PIK3CA TRPC3 TGFB2 ITGA2B GNA14 APOA1 SERPINF2 PLA2G4A THPO DGKE AKT2 RHOG GP9 RAPGEF4 GNB3 F5 AKT1 MPL DGKI ADRA2B PIK3R1 TBXA2R CD36 FGA TRPC6 DGKA PIK3R5 PFN1 F2 F2RL3 PSAP GNG4 CSK PTPN1 F2RL2 ITGB3 PRKCE RAP1A GNB1 PIK3R2 ALB PTK2 TF GNG13 SHC1 PDPK1 CALM1 GP5 DGKQ TUBA4A RAF1 GRB2 CALM3 RAP1B HSPA5 GNB2 CD63 TMSB4X CALM2 PPIA DGKD FGG RHOA PDGFA GNGT1 YWHAZ DAGLA WDR1 GNAQ CAP1 SRC PLG CFL1 VEGFA SYK APP DGKH PF4 GNAI3 RAC1 THBS1 TRPC7 STX4 KNG1 F2R ACTN4 CDC42 SOD1 MAPK3 GNG5 MAPK14 SOS1 ALDOA EGF CRK PRKCZ ITPR3 MGLL ARRB1 PRKCD STXBP3 CD9 GNA11 ABCC4 PIK3CB MAPK1 SERPINA1 GNG12 LAMP2 ADRA2A P2RY1 VAV3 GNAI1 GNA13	0.0225374	UP
CASORELLI_APL_SECONDARY_VS_DE_NOVO_UP	FOS FOSB CLU CSGALNACT1 NID1 SLC24A3 LAMC1 PLA2G16 FZD2 ENTPD1 HDAC4 EVI2B ANXA5 CEBPD SLFN12 TM6SF1 TFEC TMX4 CAPN3 TRIM27 ZMYM6 ENC1 PTGER2 SLC38A6 DPM3 KLF4 NAGPA GCA FCGRT ARHGEF40 FBN2 FAM105A SLC36A1 CNIH4 MAVS MCTP2 TGFA	0.0225526	UP
SMIRNOV_RESPONSE_TO_IR_6HR_DN	EGR1 RGS1 NR4A2 EGR3 CR2 RGS2 CD69 KLF2 BNIP3 TCL1A P2RX5 MAFF IL16 ENTPD1 ZFP36 EVI2A PTPRC KCTD12 PTPRCAP RNASE6 TMEM45A HHEX PVRIG FAM65B AIM2 DUSP2 RAB33A ITGA4 CCR6 CCL4 IER2 GPR18 CD22 SLC2A3 LCP2 TRAF5 H1FX CCR1 SIT1 TRIB1 MYC CYBB TRAF3IP3 SIPA1 ZBTB32 ACAP1 CDK5R1 LDLR POLR3G GGA2 MNT CD300A LTA CLEC2D GFOD1 SUN2 GEMIN4 KLF6 RNASET2 CACNA1A INSIG1 STS UBE2S HEY1 PLK1 ZNF318 KDM3A TLE3 CDCA3 ZNF395 VGLL4 ATP2A3 P4HA1 BUB1 INSIG2 H1F0 UBE2C PDK1 KIF14 FKBP4 TNF ARHGAP11A SLC16A3 CD55 CCNG2 SLC19A1 KIF23 CENPE DEPDC1 CENPF PSRC1 ATP8A1 TPX2 LPCAT4 CDC20 SCD KIF20A DLGAP5 CCNB1 HK2 AURKA ELOVL6 NEK2 EGLN3 CENPA HMMR C5orf30 OAS1 EGLN1 ASPM	0.0226288	UP
KYNG_DNA_DAMAGE_DN	ADAMTS1 EGR1 CTGF CNN1 CRYAB AKAP12 HSPB8 NNMT RHOB CD69 ANXA1 TMEM158 FN1 FBLN2 PRELP CXCL2 VIM FGF2 IGF1 CSF2RB LCK PPP2R2B HLA-DQA1 TGFB3 CD53 TCF4 PDGFRL ST6GALNAC2 ITGAL SERPINE2 IL11RA CALU CEBPB CCND1 SEMA4D ZFP36L1 NRP2 NGF TAF1C LIMS1 IGFBP3 C1orf61 COL3A1 PAPPA HGF TPM1 BTG3 TFPI2 DSCAM PRMT1 CRHBP SEMA3B APBA3 ATRX CDC25A ENDOU PBX1 PRKACA RBL1 CDC37L1 DAXX SEMA7A NMT1 HK1 CD36 ATOX1 MARK3 GBP1 PSG1 FLOT1 AGPAT1 GYPB FAM69A CREBBP CSDE1 TXNRD2 CCNL2 ITGB8 PDCD5 RAB11B ACE ITGB1 TBCA MORF4L1 TPR EIF3L COPS7A RHOD AP3B2 PTGER4 RPL7A SERPINB2 TP53I11 TIA1 HNRNPA2B1 EPS8L1 CIR1 ARPC1B BNIP3L CTCF UGCG CIB2 IFNGR1 ESD PRKD2 TLE1 SGCB PTPN18 EFNB1 CSNK1A1 VDAC3 PSG2 PPP2CA GOLPH3 PAFAH1B3 DNAJA1 OAZ1 HSD17B10 POMP ALDH3B2 SSR3 SHFM1 POLR2F PPA1 GALNT2 TAF10 PRSS23 ATP5I RAB6A ITGB5 IRF2 GADD45A RAB7A PCNA ARPC3 TNFRSF10B ARF1 ANKRD11 MOK LDHC KRT13 CCNH SERPINB6 ID1 PRDX4 ALDH9A1 INPP1 RAB2A ACTN4 GLRX SOD1 MED17 MT1X MT1H DLG1 NET1 RABGGTB TCF7L2 MINK1 COPB2 IFNGR2 MYD88 CCNC RIN2 LOX SUOX CAB39 HEXB EIF4E NDUFB6 SLC35B1 CYCS SNAPC3 LCN2 PRKAB1 FGFR4 SLC31A2 TWF1 RHOBTB3 GOLGA4 NDRG1 IL10RB FMO4 CCNA2 PCK2 CYP51A1 PRKAB2 GPD2	0.0228179	UP
PACHER_TARGETS_OF_IGF1_AND_IGF2_UP	EGR3 MAP1B DCLK1 RPRM BHLHE40 PHGDH IGF1 GDF15 SLC7A5 NELL2 MFAP3L PCDH8 INHBE SLC3A2 DDIT3 KRT81 SLC1A4 ASNS SDF2L1 SLC7A11 SERTAD2 ABCA12 MID1 PSPH SEC24D DNAJB9 HERPUD1 GADD45A VEGFA ASS1 IFRD1 TFF3	0.0229498	UP
PID_INTEGRIN_A4B1_PATHWAY	THBS2 FN1 SPP1 JAM2 VCAM1 CD81 TLN1 ITGA4 PRKAR1B PRKAR1A CD14 PRKACA GIT1 MDK ITGB1 PTK2B PTK2 ADAM28 MYH2 PTPRA PXN YWHAZ SRC RAC1 THBS1 DOCK1 ARF6 CRK PRKACB ABI1	0.0229616	UP
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN	CTGF BAG2 AKAP12 TIMP3 DDR2 NDRG4 FHL1 CLEC3B DUSP1 KLF2 PLTP QKI TNXB EMP3 BHLHE40 COL5A2 ELN FXYD5 FBN1 GAS7 COL4A1 FZD2 ADRB2 TMEM45A CSRP1 SLC29A1 CLIC4 COL4A2 SNX10 AQP1 CD34 PHLDA3 TMEM43 ABHD8 DAB2 GPC1 MSLN IGFBP4 GALK1 NFIC GAMT VAMP5 ENO3 SEMA3F CYB5R1 SNAPC2 UTRN BAIAP2 S100A13 SEC14L1 TRIB3 ARHGEF2 NUPR1 ABCC1 DGCR6 AGRN IFI30 EIF4EBP1 ADRA2B TUBA8 KLK8 NMT1 MEA1 PNPLA2 COL11A1 C9orf16 ASNS PQLC3 ACE S100A1 MYO1C DBNDD2 TEAD4 RNPEPL1 NFE2L1 STAT6 TRAM1 FOXK2 SLC1A5 NPPB CD151 RNF13 GSTM1 ASAH1 MAP1LC3B RHOA RBMS2 FAM134B GIPC1 PRSS23 GUK1 ATP6V0B ACYP2 SERPINB6 TMBIM1 TRAK1 ADM ITGB4 LASP1 DAP CAPG CARHSP1 FHL2 RNASE4 TALDO1 SEMA3C ACOT7 KLF4 ACP2 ANXA11 POLD4 IMMT TMEM159 ICA1 ALDH2 CSNK2A1 WWP2 SKAP2 CD9 TOB1 AVPI1 LYPLA1 DSCR3 NEDD9 CYB5B MGST3 TSPO PLIN2 LGALS9 LAMC2 ANXA4 PLAC8 SRI PAPSS2 CYP51A1 HIST1H2BC PKP2	0.023135	UP
IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR	E2F8 PCCA CASP7 OVOL2 AGPAT5 GCNT3 PAPSS2 PYCARD AP3S2 PLAC8 ERLIN1 AHCY MAOA DTX4 MRPS35 CISD1 TMEM97 DBI UBFD1 CFDP1 ERCC8 AAGAB TMEM186 RSU1 PLAA MRPL12 GMPPA SCIN LMAN2 NUP37 APIP GUSB ALDOA DDX52 CUL5 BET1 PSMA3 SCARB1 ISG20L2 ERP44 MDH1 G3BP1 EIF6 TNS3 MTG1 FAM149B1 NAA50 QARS MAPKAPK3 COMMD10 POLR3E NEBL CITED2 BID WDR73 RPN1 HDGF TSPAN31 TCN2 ZNF706 PES1 ATP6AP2 CTSZ RABEPK GFM1 WDR77 PTCD2 TEX2 CDADC1 PGAM1 DIEXF EEF1B2 VPS45 ENOPH1 GTPBP8 APEX1 MFSD10 SSR1 PARL CEBPZ PFKP GYS1 THOC5 SNUPN MPO SDF2L1 SSR2 LUC7L NPC2 ELANE POLR3C TXNDC15 SPCS3 KLHDC4 C12orf10 MAPRE2 SIGLEC5 CLUAP1 ATP6V1F NOL9 CPA3 AFAP1 KLHL23 ZNF266 GTF3A GALK1 NXT1 ZAK NOC3L RASSF4	0.0232497	DOWN
REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	MGAT4A GALNT3 PIGL EDEM3 GALNT12 ARSE MGAT4B MUC2 SAR1B PIGO PIGV GCNT3 GALNT7 GCNT1 MPI MUC5B MAN2A1 PIGG PMM1 SEMA6D MLEC STT3A ALG6 SEC23A ALG13 GGCX B4GALT5 PGAP1 B3GNT3 MUC4 C1GALT1C1 MUC13 B3GNT2 GMPPA UGGT1 DOLPP1 GALNT1 MGAT2 SEC24B PIGT B4GALT4 MAN1A1 PIGN GALNT10 DAD1 DPAGT1 PIGA PGM3 EDEM2 B4GALT3 MANEA DPM3 ALG5 DDOST PDIA3 PIGB PIGH ST6GALNAC4 ALG8 ALG3 PMM2 PIGF ALG9 DPM1 GANAB B4GALT1 MAN1B1 C1GALT1 RPN1 CANX SEC13 GPAA1 GMPPB PIGK DPM2 LMAN1 GALNT2 PREB CALR RPN2 SEC24D PIGP PIGC MGAT5 F9 SEC24C F7 EDEM1 DHPS MOGS UGGT2 ARSF DOLK ARSA MUC7 MUC5AC SEC31A GALNT8 F2 MUC16 ST6GAL1 B3GNT4 STS GALNT6 PRKCSH MGAT3 ALG12 MCFD2 B3GNTL1 MGAT1 PLAUR FURIN MAN1A2 PIGQ ARSB EIF5A PROC PROZ B4GALT2 B4GALT6 EIF5A2 FUT8 ST8SIA3 MUC6 VKORC1 GALNT11 GCNT4 ST3GAL2 ST3GAL1 DOHH ST8SIA2 MGAT4C GALNT14 ARSJ TUSC3 ST6GALNAC2 F10 PROS1 MAN1C1 GFPT2	0.0233239	DOWN
MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP	CYR61 TPM2 ACTG2 CNN1 TAGLN CLU TNS1 DPYSL3 TNC EGR2 SMARCA1 ACTA2 HTRA1 LTF FN1 FHL1 CALD1 LPL DKK3 QKI G0S2 BHLHE40 TGM2 PCOLCE BASP1 CP PIAS3 FZD4 COL16A1 SIRPA STAT5B TPSB2 GRB10 IER3 NOTCH4 MFGE8 CDH11 HSPG2 TNFAIP6 MMP2 PDGFC EXTL3 NFIC GJA1 COL7A1 GSN MEF2C PTPN14 ETS1 GFRA1 UTRN EHD1 TIMP2 ANO1 CA8 CYB5R3 CCNK FABP3 CD14 ECM1 RAD23A KDR BPGM AKT1 MMP14 CHD4 CYTH1 HK1 EPB41L2 TGFBR1 COMT CITED1 OGFR CRIM1 VCAN NFIB WEE1 PTK2B RPL27A SNTB2 MAPK8 MARCKSL1 TRA2B COL8A1 COPS2 TSC22D1 TUBA4A TLE3 JAG1 CNN3 EPAS1 BMP1 TPP2 ITGAV GALNT2 ETS2 ACADVL PICALM CAP1 SFPQ HDLBP HAS2 VEGFA PLAT RUNX1 SIAH2 F2R S100A6 APLP2 FZD6 SOCS2 CLIC1 UBE2D1 LASP1 PTPRK ADAM10 NRIP1 MAPK14 NET1 RAB5C SAT1 CAPG LIPG HES1 TGIF1 ARL4A IER5 GUSB SLC2A1 CYB561 CRK PRKACB FMR1 CDKN2B CDKN1A IL13RA1 CSNK2A1 ATP1A1 DNM2 FABP5 SPIN1 WNT5A CYC1 RAB17 SOX9 RPS6KA3 F3 ST14 TMEM2 HN1 AK2 CPD ACAT1 DLAT KRT18 GALC PLOD2 SERPINB5 ACAA2 TJP2 CEACAM1 EGLN1 GALNT3 FOXA1	0.023573	UP
KOBAYASHI_RESPONSE_TO_ROMIDEPSIN	FOS SYT11 ELOVL4 ARL4D NGFR MICA DENND3 TNFAIP6 LPIN1 FABP6 MERTK RB1CC1 GTF2B PMEL KLHL7 EFNB2	0.0236761	UP
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_DN	HMGCS2 HSD17B2 PROM1 CRYL1 ELOVL6 G6PC PAPSS2 SERPINA6 LIPC ME1 SLC25A10 C8G SNX27 PRLR ELOVL2 DIO1 ACTL7B RPL22 CYP4A11 CELA1 CDC5L PKLR ALAS2 POM121 SLC26A1 SULT4A1 GHR LIFR RELN NRP1	0.0238891	DOWN
BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_DN	LOXL1 IRS1 WIPF1 FBN1 FYN ACTC1 ACTN1 NRTN SEPT5 AMH INSL3 ADRA1B MAP4K2 ATP1A3 SHOX INPPL1 LRCH4 KRT17 MDK INSIG1 ADCYAP1 GTF2F1 PPM1G PFN1 TUBG1 HMGN2 ITGA3 EPHX1 YWHAH ATP5D AQP8	0.0239913	UP
REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE	KCNMB1 GUCY1A3 GUCY1B3 PDE2A PDE1A KCNMB4 PDE5A PDE1B KCNMB3 NOS3 PRKG1 PDE3A PDE6G PDE10A NOS1 KCNMB2 PDE9A PDE11A PDE6B NOS2 GUCY1A2 PDE3B PRKG2 PDE6A	0.0240533	UP
HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP	BCHE TIMP3 SFRP1 CCL21 DUSP1 VEGFC SPP1 EMP3 ITM2A DAPK1 GYG2 GPC3 PRAME SGK1 TACR1 FABP3 CGA MAGEA10 ABI3BP GAGE12I HIST2H2BE ELAVL2 EDNRB TNFRSF11B WNT5A VAMP8 WDR44 NEK2 AGT	0.0241087	UP
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	THBD CAV1 FN1 GRB14 ITGA5 SELL ANGPT1 JAM3 JAM2 ITGAM COL1A1 FYN CD48 COL1A2 PECAM1 ITGB2 SIRPA SIRPG LCK TEK PROS1 ITGAL CD2 SLC7A5 SELP SLC7A10 ATP1B2 DOK2 PTPN6 SPN FCER1G PLCG1 L1CAM ITGAX MERTK LYN APOB PIK3CA SLC3A2 PROC ANGPT2 MAG SLC16A8 OLR1 PF4V1 PIK3R1 SLC7A7 ITGB1 SLC7A11 F2 ITGB3 TREM1 PPIL2 HRAS PIK3R2 CD47 SHC1 SLC7A8 GRB2 ANGPT4 SLC7A6 ITGA3 PPIA ITGAV SLC7A9 SRC PF4 SLC16A3 SOS1 ATP1B3 CD58 KRAS ATP1B1 PIK3CB YES1 GRB7 MMP1 F11R CXADR SLC16A1 NRAS BSG	0.0241438	UP
ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS	EGR1 EGR3 EGR2 MAP1B TUBA1A JUN MAPK10 PIK3CD CREB5 MAPK8IP2 TERF2IP MAPK8IP1 CAMP PIK3CA NTRK1 MAP2K7 MAPK8IP3 PTPN11 AKT1 PIK3R1 GAST ELK1 EGR4 FRS2 CREBBP MAPK8 DAG1 SHC1 BRAF ASAH1 CREB1 GNAQ CREB3 SRC PIK3C2G ATF1 MAPK9 MAPK3 MAP2K4 CRKL TH RPS6KA3 MAPK1	0.0241869	UP
GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP	CYR61 EGR1 NAP1L3 THBS2 TUBB2B CCL2 CSGALNACT1 RGS2 NID1 NCAM1 NAV3 HTRA1 CXCL12 HBEGF SCRG1 DFNA5 WIPF1 NRP1 TGM2 JAM2 SLC43A3 MYO5A IGFBP7 TNFAIP2 TNFAIP8 TRIM9 DTNA NR3C1 GIT2 ST3GAL6 MARK1 ARSJ ZNF467 ATP7A SETD5 C3AR1 FJX1 TTC9 LYN RNF130 CHD8 SBNO2 MAPRE2 ZNF22 B3GAT1 FLT1 GPR176 RPGR C2CD3 SYT12 ZNF286A CA5B PPM1H OLIG2 MATR3 TMEM206 THOC1 SRRM2 KDM5C RPL15 TP53 SSX2IP CRYAA CCT3 KAT7 RBMX TRIM44 JMJD1C DNAJA4 PRPF3 TSR2 MANBA P4HTM WAC HUWE1 LIG3 WLS EN1 ID2 SLBP USP14 CCL7 MYH9 GLB1L HDAC2 CAMK1D ZMYM2 DYNLT3 CLSTN1 GLA MAU2 HLA-E PITRM1 GOT2 KIF24 BRD8 TDRKH BTBD7 ATP6V1B2 PDK1 GALNS RTP4 ANKRD28 MBTPS2 WDR37 EMP2 CPSF6 WDR33 APC RNF138 CENPE RIF1 PFKFB2 YTHDC2 MOSPD2 PLXNA2 HOXA10 NR2C2 ACO1 SORD YES1 MAOA RP2 PCSK6 SLC20A1 TRIM2 GK PDE8A ANK3 DTL ZNF518A GMDS CRYL1 WASL GATA6 ARHGAP32 PITX2	0.0244092	UP
CHANG_CYCLING_GENES	PBK MAD2L1 SDC1 MAPK13 HMMR CENPA HIST1H2AC GMNN CCNA2 CDC25C AURKA MELK CASP3 DLGAP5 TOP2A RAD51AP1 CCNB2 HN1 FOXM1 MET DHFR TPX2 CKS2 CDC6 EZH2 BUB1B PSRC1 CENPF HELLS DEPDC1 CDKN3 PRPS2 KIF23 LMNB1 NUSAP1 PRIM2 KDM5B SCML1 NCAPD2 ASF1B KIAA0101 KIF22 GINS2 MCM4 ARL4A CDCA8 AMD1 CDK1 SMC4 RFC2 BIRC5 NCAPH UBE2C SPAG5 PTTG1 ZNF814 FAM64A ILF2 NLRP2 PCNA HJURP TSN CKAP2 CENPM RRM1 H2AFX BUB1 EFHC1 RRM2 BUB3 DKC1 ANKRD10 TUBA4A CDKL5 PLK1 ATAD2 FEN1 USP1 TUBB4B PRIM1 CENPQ ITGB3 DIAPH3 KIF20B WSB1 PHTF2 MCM6 RANGAP1 UBE2S FANCG EXO1 MCM5 PWP1 DONSON RECQL4 TRIP13 ZNHIT2 CCNF KIFC1 E2F1 GINS3 CDC25A PRR11 GTSE1 TIPIN MNT IFIT1 RFC4 TACC3 BARD1 TUBB WDR76 CIITA ANP32E TIMP1 SGCD ADAMTS1	0.0245561	DOWN
VALK_AML_CLUSTER_13	CAV1 RUNX1T1 THSD7A FBLN5 ROBO1 LAT2 LCP1 GRK5 ADRA2C ADCY7 C11orf21 HSPG2 STK32B TRH BAIAP3 VOPP1 POU4F1 CACNA2D2 NARFL KDM4B C15orf39 IL5RA PNMT NCALD NBL1 ITGB4 VLDLR SLC25A1 PSD3	0.0246089	UP
GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP	OGN CCL2 NNMT DLC1 TRIB2 DKK3 C3 TACR2 FSTL1 PRELP CAPN6 IRS1 COL5A2 SLC24A3 ANGPT1 SEPT6 ELN MYOC CP IGFBP7 KCTD12 OAS2 ELOVL4 WISP2 BST2 IFI44 AQP1 PDGFRB BGN CD2 INHBB CEP112 HSD11B1 TMEM151B LIFR ADCY7 SLFN12 SAMHD1 NACC2 STEAP4 GHR TOR1AIP1 CXCR5 DNM3 RECK MX2 CLIP1 PTHLH MMD PMEPA1 FES SP110 FJX1 TRIM8 CDK5R1 COL3A1 PATZ1 N4BP2L1 COL5A3 IFIT1 ZBP1 PFDN5 ADCY3 KCNA6 MX1 ISG15 IAPP DPF3 COL9A1 CSF1 OSGIN2 LIPA SOCS1 DMP1 PLA2G2E IKBKB TXNIP PPP1R10 TLR2 SMG6 NEUROG3 PRF1 CDON ABCC8 CRHR1 HOXB8 IRF7 NCL SP100 NECAB2 ELK1 UBA7 PLEC HIPK2 KCNMB2 TRAFD1 ACTB MEPCE RBMX ADAR ENC1 ABI3BP TOR3A CXCL10 IRF9 USP18 TUBB4B KALRN POU3F4 CCL7 ATG10 EIF2AK2 STAT1 CDCA3 GSTM1 HHAT IFIT3 PES1 COL4A3 HLA-E ZNF672 PRSS23 DAPK2 IRF2 PARP3 BCR SLC9A8 OXA1L CFB HOXB5 KNG1 IRF1 IFI35 RTP4 UBXN2B USP25 TAP2 METTL7A PARP12 TRIM21 PSMB10 RFXANK EGF SOD2 EBNA1BP2 RIN2 IFIH1 FBXW2 IFIT2 TMPO FAS TMEM140 TRIM34 LGALS3BP IHH LY75 NEDD9 NCK1 TRIM25 CASD1 VDAC1 MOCS1 CPEB3 GRHL2 DDX60 HOXB7 MEST HSD11B2 CASP7 TLR3 RSAD2	0.0246444	UP
XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR	CYR61 ZEB1 EREG MAFF IFI6 IFIT1 TSC22D2 MX1 ISG15 PLAUR IRF7 TRMT2B MARCH6 OAS3 LSM5 THBS1 SLC9A1 PLSCR1	0.0247351	UP
NEMETH_INFLAMMATORY_RESPONSE_LPS_UP	PTGS2 MLLT11 ATF3 BCL2A1 TGFB1 CCL3 FCGR2B ACSL4 DEGS1 HCLS1 TPST1 IFI16 LTB RGS16 C5AR1 ICAM1 SRGN IER3 IER2 CEBPD SLFN12 SAP30 LCP2 DAB2 TNFRSF1B CD44 C3AR1 NFKBIA APBB1IP JUND PML ODC1 RCN1 TNFSF9 STK10 MAPKAPK2 CASP4 FURIN HCK IL1RN MSR1 WSB1 IL1RL1 SLC11A1 ETF1 EIF1 ADAR MARCKSL1 KPNA3 EIF2AK2 MAP2K1 STAT1 CFLAR SQSTM1 BCL2L1 ETS2 TOP1 MT2A CITED2 NFKB1 TAP1 RNF11 TNF GLRX IFRD1 SAT1 SOD2 TNIP1 SLC2A1 TXNRD1 CDKN1A PRKCD CLN3 GCH1 TRIM25 SLPI PNP SLC20A1 GK PIP5K1B MYO10 HMGCR	0.0248416	UP
NIELSEN_SCHWANNOMA_DN	GAS1 KIAA1462 FBLN1 RBFOX2 MFAP2 SNAI2 DPEP1 SLC7A2 ADCY1 TBX3 ASS1 EGFR FBN2	0.0248815	UP
HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN	FOS EGR1 P2RY14 EGR2 ANXA1 DUSP1 LPL MITF MMP9 S100A4 ZFP36 CXCL2 CSF1R SIRPA BTG2 TRPV2 MRC1 C5AR1 GRK5 SAMHD1 DAB2 FGR LSP1 PLEK ZFP36L1 CYBB NOV CLEC7A FPR1 C3AR1 TGFBI MMP8 MERTK PHLDA1 EHD1 IL1B CCR5 LIPA MCL1 TLR2 HCK PILRB VCAN FFAR2 MSR1 SLC11A1 PSAP TF ID2 CLEC4A AQP9 FCGR1A ARG2 KLF4 PLSCR1 LCN2 LITAF CPT1A CTSS TPD52 NDRG1 GCNT2 ANXA4 UPP1 CDH1 CA4 STX3 HIST1H1C IL1R2 IL18	0.0248857	UP
MOREIRA_RESPONSE_TO_TSA_DN	ICAM1 CX3CR1 CD3D CD3E CD247 LAT IL2RA FGF18 RARB NOTCH1 ENTPD2 NOTCH2 SLC3A2 WNT4 ALPL WNT7A METAP2 OGDH	0.0249131	UP
BURTON_ADIPOGENESIS_8	OGN PTGIS TIMP3 ACTA2 NCAM1 FGF7 TUBA1A PLTP LAMB2 EMP3 FXYD5 RAB31 VCAM1 SERPINF1 PDLIM7 MSN ANXA5 PRAF2 SLC7A5 PDPN PLA2G7 SCPEP1 BDNF PLD3 VCL MATN4 ZFP36L2 B9D1 TES MAPKAPK2 SPTAN1 CD99 SLC1A4 DSTN NSA2 RPS6KA4 PSAP SMAD6 GSTM2 GNB1 COL4A5 SKI TAPBP TNFAIP1 MYH9 TMSB10 TMSB4X LEPROT ASAH1 MAP1LC3B ITGAV USP22 PRSS23 RAB7A CAP1 TPBG PLXNB2 APP SERPINB6 F2R PRDX4 KDELR3 CAPG BAX LOX FLNB GBA PRR13 CTSA LAMP2 TSPAN6 EMP1 ANXA3 HMGCR SLC38A4	0.025084	UP
LIAN_LIPA_TARGETS_3M	RGS1 GPNMB FCGR2B SLC15A3 MYO5A C1QA CXCL2 TNFAIP2 LY9 GDF15 MAFB CFP FCN1 STEAP4 C1QB CCR1 PLA2G7 C3AR1 FCER1G MMP19 FKBP5 MMP8 S100A9 DNMT3A CAMP CXCR2 UTRN ACP5 MARCO FCGR2A SEMA7A TLR7 IGSF6 CD68 MSR1 CD5L SLC11A1 FABP7 MMP12 CTSB CD244 TREM2 CLEC4E SNX6 NEU1 HMOX1 IL1R2 APOBEC1	0.0252222	UP
AMIT_EGF_RESPONSE_120_HELA	TAGLN GEM C8orf4 HBEGF CYP1B1 AMOTL2 MAFF CXCL2 LAT2 RUNX3 MAP3K14 GDF15 NAB2 CHST3 EPHA2 DUSP6 CXCL1 SNAI1 DUSP4 IL27RA AREG CLCF1 EPHB4 BDNF PHLDA1 JUND FOSL1 PUS3 ZFP36L2 MATK FOXC2 MCL1 TBL3 KDM6B CYTH1 DAXX PLAUR OGFR MVD CDC42EP2 ARPC4 RPS10 MAP2K3 CEP104 ZNF747 DAG1 HNRNPH1 CDC27 IRS2 JAG1 MCF2L NDEL1 GADD45A TNFRSF10B BCL10 UBXN4 BIRC2 SAT1 IER5 IER3IP1 ARRB1 VPS37B CDKN1A F3 JUP TGFA	0.0256153	UP
REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6	PSMC6 CDC6 PSMB8 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 CDK2 RPS27A UBA52	0.0256205	DOWN
ZHANG_TLX_TARGETS_UP	SLC4A4 HMMR TTK SHMT1 KIF11 CCNA2 CEP55 TTPA GINS1 TOP2A DTL ORC2 CHEK1 SLC12A2 ZWILCH RAD51AP1 MKI67 RBBP8 EZH2 CENPF SMC2 RIF1 PLK4 CENPN TMPO HAUS6 SKA1 MCM4 NET1 SMC4 BRCA1 TYMS WDHD1 NUP85 NCAPG NCAPG2 TARDBP DIS3 SPAG5 SMC6 CA3 SRSF1 BUB1 DEK TIMELESS FANCI POLA1 LIG1 HAT1 CASP8AP2 DNA2 ERCC6L USP1 CHAF1B MCM10 PRIM1 INCENP CDC45 ZNF280D RAD54L DNAJC2 EXO1 POLE RFC1 BLM FAM111A NASP TRIP13 RBL1 PPAT HMGXB4 FANCA TIPIN RAD51C ATM SHCBP1 PEG3	0.0257344	DOWN
REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21	CCNA2 PSMC6 CKS1B SKP2 PSMB8 CDKN1A CCNE2 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 CCNA1 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSMD14 SKP1 PSMB6 PSME2 CDKN1B PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 CDK2 RPS27A CCNE1 UBA52 CUL1	0.0260303	DOWN
FURUKAWA_DUSP6_TARGETS_PCI35_DN	ADORA2B PBK PDSS1 MAP7 PRC1 CENPA LAMB3 KIF11 CCNA2 CEP55 AURKA MMP1 CCNB1 DLGAP5 DTL STIL CCNB2 IVD TPX2 CENPF PHLDA2 NUSAP1 KIF2C RACGAP1 CCNE2 NCAPD2 EBNA1BP2 MCM4 NEDD4L ARHGAP11A NCAPG AURKB PRMT5 HJURP CKAP2 RRM1 POLQ ACOX2 SIPA1L3 ORC6 SLCO2A1 WDR3 PDLIM2 PRIM1 KIF20B GCGR MCM5 RTEL1 BLM HPCAL1 RFC4 ETS1 NGF KHDRBS3 PMEPA1 SHCBP1 EPHA2 DYSF CTNNAL1 LAT2 MAFF CALB2	0.0260608	DOWN
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP	CCL2 NNMT LTF LPL GPX3 S100A4 VCAM1 S100A8 C1QA ITGB2 PTPRC LAPTM5 CSF1R SIRPA BTG2 TSPAN4 SNX10 HLA-DQB1 TYROBP CD52 LCK HLA-DQA1 CYTIP CD53 NCF4 HLA-DMA CCL4 HLA-DRB1 CFP SAMHD1 LCP2 C1QB RRAS CXCL1 CCR1 HLA-DMB RND2 FGL2 CYBB CD74 AIF1 FPR1 LBP UBD CYP26A1 S100A9 PLD3 CAMP SELPLG APBB1IP WARS PRTN3 NOP2 CD14 TLR6 S100A11 IL18BP CD7 ORM1 HCK SCMH1 CXCL9 GBP1 SH3GL1 PROCR CD68 MSR1 CD5L PTPN1 CCL5 MMP12 NCOA3 PSMB9 QSOX1 PLK1 HPX TAPBP GDF5 STAT1 TMSB10 TMSB4X DCLRE1A FCGR1A IQGAP1 MT2A LGMN ORM2 GRN TAP1 CYBA S100A6 BIRC5 CTSC SPTLC2 MCM4 ATP1B3 CYB561 RBM3 MCRS1 LGALS3 LITAF CASP1 SLPI CTSS PDK3 NAMPT SCD TRAF3IP2 PLAC8 STX3 TFF3 GLTP PROM1	0.0262313	UP
LEE_LIVER_CANCER_CIPROFIBRATE_DN	NETO2 REG1A HSD3B2 ACADSB SULT1B1 OTC PCK1 DMBT1 ABAT G6PC C4BPA SELENBP1 SERPINA6 EFNA4 SLC37A4 AKR1C1 NR1H3 EGFR RNASE4 HBP1 OAT DPP4 TNNC2 KRT13 CA3 TNFRSF10B IL1RAP LECT2 MCM7 CYP2F1 PAH KRT4 MCM10 HAL SLC17A3 MBL2 PNLIP BHMT SLC1A2 CYP2E1 BAAT PNLIPRP1 CYP7A1 HPD PRODH PON1 ELANE CTRC GSTA4 CYP7B1 TNNI2 MAPKAPK2 TNNT3 CA5A ETNK2 WNT10B SLC2A2 CYP26A1 PIPOX GPR37 HSD11B1 TRPV2 KYNU BCL6 PPP1R3C	0.0269247	DOWN
MISSIAGLIA_REGULATED_BY_METHYLATION_DN	CYP2J2 PRC1 RFC5 NEK2 GMNN SHMT1 CCNA2 CDC25C AURKA HMGB3 DLGAP5 PIR ZWINT CHEK1 EBP MKI67 YES1 FOXM1 DHFR CDC6 UBE2K EZH2 BUB1B NDUFS3 MECOM CENPF SMC2 CDKN3 ARL6IP1 CECR5 ENOSF1 CENPE KIF23 LMNB1 PAICS NUSAP1 TMPO RNASEH2A ESPL1 ACAT2 KIAA0101 KIF22 CDT1 CDK1 SMC4 ITGB4 TYMS TK1 KIF14 NCAPH RPA3 UBE2C HNRNPAB NCAPD3 PRKDC SMC1A CENPM RRM1 IFT20 RCC1 DEK RAB26 DCLRE1A POLD2 LBR LIG1 FASN MICU1 KIAA0586 POLD3 HAT1 ZNF175 H2AFV DTYMK LANCL1 HMGB2 H2AFZ KNTC1 PCBP2 EXOSC8 HMGN2 FBL PRIM1 RBMX HNRNPA1 HMGB1 CDC45 ARHGAP19 MCM5 DUT RANBP1 SNRPA CSE1L CAD SNRNP40 STMN1 KIFC1 DNMT1 ANP32B SRSF3 HNRNPL GMPS TRIM28 ILF3 MDFI AARS FUT8 FOSL1 RFC4 MDC1 CDKN2C MSH6 NRGN PSIP1 SEMA3A PCDH7 CAV1	0.0271382	DOWN
BIOCARTA_INSULIN_PATHWAY	FOS IRS1 JUN SRF INS PIK3CG PIK3CA PTPN11 PIK3R1 ELK1 HRAS MAPK8 SHC1 RAF1 MAP2K1 GRB2 SLC2A4 RASA1 MAPK3 SOS1 INSR CSNK2A1	0.0271625	UP
PID_TCR_PATHWAY	FLNA FYN PTPRC RASGRP1 LCK ITK INPP5D MAP3K14 HLA-DRA PRKCB CD86 CD4 RASGRP2 MAP4K1 HLA-DRB1 LCP2 CD3D CD3E VAV1 CD247 PRKCQ PTPN6 ZAP70 CD28 LAT PLCG1 PRKCA MAP3K8 FYB GRAP2 PTPN11 MALT1 WAS IKBKB AKT1 TRPV6 IKBKG STIM1 CSK PRKCE RAP1A CD80 HRAS CBL SH3BP2 SHC1 PDPK1 GRB2 CD3G PTEN TRAF6 CDC42 BCL10 SOS1 GAB2 KRAS NCK1 CHUK STK39 NRAS	0.0272124	UP
WU_CELL_MIGRATION	CYR61 ADAMTS1 PTGS2 AHNAK2 TPM2 AKAP12 TIMP3 CLU TUBB6 ARHGAP29 NNMT RBPMS MAP1B FBLN1 WWTR1 AXL SACS FN1 EFEMP1 IGFBP6 DKK3 EMP3 TGM2 RAB31 S100A4 LIMCH1 COL4A1 CHST15 GNG11 COL6A2 FYN MSN IGFBP7 PODXL VIM SIRPA TNFAIP2 TSPAN4 FGF2 ARL4C KYNU COL4A2 ARHGDIB DSE ARID5B BST2 GLIPR1 GATA3 COL18A1 CTSH PPL BICC1 DAPK1 SRGN RAC2 NR2F2 CXCL1 GALNT14 EEF1A2 LPAR1 PDGFC GJA1 SERPINE1 TGFBI PTGES IGFBP3 CDH3 TFPI2 TM4SF1 LOXL2 FOSL1 SNAI2 AQP3 DCBLD2 GSTM3 ZNF22 TXNIP GLUL KRT17 OLR1 GJB3 NMU MAGEA3 EPB41L2 RGS20 TRIM29 VCAN CST6 PTGER4 FKBP11 MAGEA6 S100A2 UGCG KRT7 TUBA4A TACSTD2 VGLL1 JAG1 EPAS1 DYNLT3 ASAH1 IL1A S100P MT2A SFN SMURF2 THBS1 S100A6 HIST1H2BK ERAP2 IGF2BP2 GPR87 ITGB4 MT1X MT1G CAPG CD55 MT1E MT1F TSPAN13 GALNT1 MTUS1 PLAGL1 EFNB2 LGALS3 FABP5 WNT5A AKR1C1 TNFRSF21 CSTB SCNN1A NEDD9 CD24 RHOBTB3 SLPI SOX9 LIMA1 DTX4 ST14 PLIN2 AKR1C2 MAOA AIM1 EPS8 JUP SH3YL1 LAD1 EPCAM SPINT1 PLAC8 SQRDL PIR FXYD3 KRT18 PKP3 KRT19 CLDN4 LAMA3 CDA KCNK1 SERPINB5 CDH1 CXADR MEST KLF5 CLDN7 MAPK13 PERP F2RL1 AGR2 HMGA2 GRAMD3 S100A14 TMEM30B RAB25 SLC27A2 GALNT3 AKR1C3 RNF128 ESRP1 EHF	0.0272407	UP
TAVAZOIE_METASTASIS	PLN PTGS2 IGFBP5 PLP1 TNC RGS2 MEOX2 CXCL12 EAF2 PLCB1 ROBO1 LAMA4 EREG COL1A1 DZIP1 MYOM1 KYNU SULT1C2 GATM ZDHHC17 AMPH KLHL11 MARCH1 SLC4A7 FOXA2 TTC9 MTMR7 SIGLEC8 MERTK VCL CSF3 SPANXC ABCB9 ANO1 CA8 NLGN4Y P2RX2 KLF9 KRT81 NKAIN1 KISS1 IFNA8 ALK GDF11 CDC14A DPYSL4 FCHO1 PTPRN2 CCDC81 USP9Y MTAP MAGEA3 KLHL28 FRS2 FCN2 GPR17 ST6GAL1 STX11 CHIA RARA SERPINB2 PARK2 CRP MDM2 CXorf57 KCNJ15 NIPAL3 ASMT LRP2BP F9 CNTNAP2 PDGFRA MYEF2 THAP9 KIDINS220 TRIM23 FAM135A UTY ZNF750 XYLB DLG2 SSX1 IL13RA2 ZNF257 ZNF682 GNRH1 ABCG5 SOX4 CYP3A43 HAPLN1 EFCAB11 HOXA7 CD24 RAP1GAP2 TSPAN12 HIST1H2AG ZBED4 HPGD MMP1 AKAP9 LRRC31	0.0272416	UP
TAVOR_CEBPA_TARGETS_DN	GAL MMRN1 THBD MAP1B OAS2 ICAM2 GATA2 A2M AKR1B1 H1FX IFI6 MYC LYL1 GJA1 MC1R TBXAS1 KLRK1 ISG15 RIN1 FOXO1 GP9 FXR2 ZBTB48 PFN2 ITGB5 CRADD TNFSF10 SERPINB1 IFI27 PLOD2	0.0272418	UP
REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	NCAM1 COL5A2 PRNP COL6A3 COL4A1 COL1A1 FGFR1 COL6A2 CACNA1H FYN COL1A2 COL4A2 COL6A1 NRTN GFRA2 ST8SIA4 COL5A1 ST8SIA2 CNTN2 COL9A3 COL3A1 GFRA1 CACNB2 SPTB SPTBN5 CACNB4 ARTN COL9A2 COL9A1 AGRN COL2A1 PSPN SPTBN4 SPTAN1 CACNA1G GFRA4 COL4A4 GDNF CACNA1I SPTA1 HRAS SPTBN2 PTK2 COL4A5 SPTBN1 RAF1 MAP2K1 CACNA1S GRB2 CACNB3 NCAN CREB1 CACNB1 COL4A3 SRC YWHAB MAP2K2 MAPK3 CDK1 SOS1 RPS6KA5 KRAS MAPK1 NRAS	0.0273474	UP
LENAOUR_DENDRITIC_CELL_MATURATION_DN	RTN1 CES1 HTRA1 SDC2 ITPR1 CD37 C3 EMP3 ELK3 MMP9 S100A4 SERPINF1 PDLIM7 S100A8 CORO1A EVI2A CXCL2 CSF1R BTG2 KYNU CTSK ARHGDIB CLEC2B CYTIP C5AR1 CD180 ITGAL IER3 SLC1A3 FCN1 LST1 PPBP DUSP6 TNFRSF1B CD163 CCR2 CD44 FGL2 IDS CYBB PTAFR C3AR1 STAB1 FCER1G NINJ1 TROVE2 S100A9 NMB NFKBIA FYB TLR1 IL1B ZFP36L2 ISG15 CD14 IL2RG MAPKAPK2 PRRC2A BRD2 S100A12 TXNIP FCGR2A DOK1 OLR1 PLAUR CHI3L1 IRF7 BCAT1 NAP1L4 RAB3GAP1 LYZ AMPD3 CXCL3 PTK2B SLC11A1 NUP214 UPK2 PPP2R5D SNX17 SF3B4 PPIB MARCKSL1 CTBP1 TSC22D1 TUBA4A PUF60 CXCL5 HSD17B10 ATP2A3 GLA HIST1H4C KRT10 LTA4H LGALS2 LHFPL2 LGMN NFYC SDF2 PF4 BST1 NCOA4 ALG3 DHX8 TNF SORL1 ADAM10 SREBF2 SOD2 SOS2 PLSCR1 TAX1BP3 PPIF ME1 AKR1C1 HIST1H2BE PSEN1 NAMPT SERPINA1 GK FBP1 GSR IL6R EMP1 IL1R2 SPINK1 ANPEP	0.0274212	UP
GERY_CEBP_TARGETS	FOS CRYAB ATF3 GREM2 CLU IGF2 RGS2 ACTA2 FGF7 HBEGF DUSP1 LPL DFNA5 PPP1R15A C3 SERPINI1 RRAD NRP1 DCN PRNP EREG PEA15 S100A8 JUNB FOXF2 TMEM45A BTG2 IFI16 RGS16 IER2 CRABP2 CXCL1 S100A3 DBP TNFAIP6 ANGPTL4 NGF HGF PIM1 SH3GL3 CYB5R1 RASL11B APBB1IP BAIAP2 BAG3 CAPRIN2 TRIB3 CD1D DDIT3 ABCD2 ORM1 PLAUR ABCA1 FOXG1 HP NR1D1 TGM3 VCAN MVD PROCR CD68 PER2 GADD45B SERPINB2 SSR1 CD47 GML ID2 MKNK2 RNH1 HSPH1 RDH11 MAFK ACSL1 HSPA1A GLA DNAJB9 DNAJB2 HIPK1 GADD45G LPGAT1 PLAT CHORDC1 ALDH3A1 KNG1 PTX3 DNAJB1 GLRX HIST1H3F IFRD1 SAT1 ID3 FHL2 HGSNAT NSDHL KLF4 CXCL6 NUS1 LSS LCN2 TFRC GCH1 ECHS1 WWC1 ANK3 HMOX1 POSTN ELOVL6 XDH HTATIP2 BCKDHB TOM1L1 HMGCR ABHD5 PPARG HIST1H2BC HSPA1B GIPC2	0.0274528	UP
RAMPON_ENRICHED_LEARNING_ENVIRONMENT_EARLY_UP	TAC1 MFAP5 PTGDS VAMP2 DNMT1 PHC2 AP2M1 CALM3 TLK1 HNRNPM HSPA5 RHOA MAP4K3 MFAP1 TRIM25	0.0278289	UP
ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF	EGR1 CTGF TAGLN EGR3 ARHGAP29 FSTL1 JAM2 GFPT2 GLIPR1 NAB2 LIFR PTHLH CLCF1 INHBA KLF10 SPHK1 HOXC13 HS3ST1 RNF24 HOXB8 CLIC3 CDC42EP2 ENC1 PAX9 ZNF189 LY6G6C CLK1 KIR2DL4 CCNJ CITED2 GLS CHIC2 F3 SMAP1 KLF5 ARL14 IL7	0.0278968	UP
REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL	AMACR ABCB11 SLC27A2 ACOT8 HSD17B4 SCP2 CYP27A1 AKR1C4 ACOX2 AKR1D1 BAAT CYP7A1 SLC27A5	0.0281081	DOWN
YAMAZAKI_TCEB3_TARGETS_UP	CYR61 CRYAB TIMP3 GREM2 CLU TFPI FHOD3 THBD SGCE NR4A1 NID1 SERPING1 SPOCK1 CDH5 FBLN2 EFEMP2 AMOTL2 SOX17 LAMC1 COL4A1 SPARC PTPRM COL4A2 ZFHX3 SRGN RAMP2 PARVB ZYX NR2F2 GHR CALU MFGE8 SNAI1 MDFIC FLRT3 HSPG2 SERPINH1 IGFBP4 GNA12 DOCK9 LAMA1 TYRO3 LPP CYP26A1 PDE1B EPHB4 KIT CCND2 FAM189A2 PXDN MYL3 JUND PLOD1 WARS GRINA FUT8 CASKIN2 RCN1 CUL1 PTH1R GLUL MAN1A2 HS3ST1 STRA6 FURIN HOXC6 MBNL2 CITED1 GNAS MSL3 SRPRB CD38 ITGB1 PSAP LAMB1 NID2 MYH6 CST3 COL4A5 TCERG1 KALRN CALM1 ID2 TTR LRPAP1 USP46 YAF2 HSPA5 SLC7A6 B2M PSPH EPAS1 CDC42EP1 SLC7A1 COBLL1 CTSZ P4HA1 GALNT2 HERPUD1 BACH1 FKBP9 GNS PTPN9 TMED2 LGMN TNFRSF10B CITED2 VEGFA PLAT RRBP1 GANAB SLC38A1 P4HB PANK2 APP ARF4 ATP6AP1 FNDC3B ERP44 LMBRD1 AMFR CLIC1 KDELR3 PDIA3 SEMA6A EXT1 KDELR2 SAT1 TCF7L2 ANXA2 PRPF38B CCNC FNDC3A CREB3L1 ATP1B1 TAX1BP3 P4HA2 EPB41L3 F3 VAMP8 SEMA6D DDAH1 DYRK2 FDX1 PLOD2 ENPEP RCOR1 TST SLC16A1 MPZL2 AQP8 SPINK1 GATA6	0.0281267	UP
GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP	FOS ASPN CRYAB CLU EGR3 SFRP1 ID4 SULF1 SORBS2 BEND5 GRB14 ISLR RCAN2 COLEC12 CP SVEP1 MAN1C1 KCTD12 C1S LMCD1 PDGFRL CD34 CDH11 PTN FLRT3 TGFBI L1CAM CLEC11A NUDT7 CDH3 IFIT1 HDAC9 SEMA3B C14orf169 FABP3 NTN1 CYP7B1 GAL3ST4 KCNF1 MTUS2 ABCA1 PDE10A SLC1A6 PROCR AKIP1 FOXRED2 CCL5 HEY1 PMAIP1 TINAGL1 PPIG SLC5A7 PDGFRA HAS2 INTS12 GNRHR EPHA1 GLRX ADM GAS2 METTL7A CRIP1 S100A10 KDM6A IL13RA1 GCA ATP1B1 CTBS RAB40B YIPF5 MYO1B POSTN MARCH3 ENPP1 IL7 HSPA1B SLC38A4	0.0281292	UP
KEGG_TYPE_I_DIABETES_MELLITUS	CPE HLA-DOB HLA-DQB1 HLA-DQA1 HLA-DRA HLA-DPA1 HLA-DMA HLA-DRB5 CD86 HLA-DRB1 INS HLA-DRB4 HLA-DMB HLA-DPB1 CD28 IL1B LTA PTPRN PTPRN2 IL12A FASLG PRF1 HLA-DOA IL12B CD80 GZMB GAD1 IL2 IL1A HLA-E IFNG HLA-C HLA-G HSPD1 HLA-B HLA-A HLA-F GAD2 TNF ICA1 FAS	0.0281342	UP
HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP	ZFPM2 CR2 TGFBR3 PBX3 SELL FXYD5 RHOH GIMAP4 HLA-DQA1 PACS1 RAB6B STOM MS4A6A BCL2 CIITA CDK5R1 APOE CSF1 STAT4 CUX2 LRFN4 TUBA3C ARL2 RABAC1 FAM102A RPA1 POU5F1 JAK2 GAD1 IBTK ARRB1 EIF2AK3 FCGRT ENTPD6 NEU1 PCK2 CENPA	0.0281434	UP
PID_IL8_CXCR2_PATHWAY	PLCB1 ELMO1 DNM1 DOCK2 GNAI2 PRKCB RAC2 FGR PIK3CG ARRB2 GNA15 PRKCA LYN CXCR2 PRKCG PLCB2 GNA14 PLD2 AKT1 HCK GNB1 CBL PDPK1 VASP PLCB3 PPP2CA PPP2R1A RAB7A RAB5A RAB11A ARRB1	0.0281558	UP
DORN_ADENOVIRUS_INFECTION_12HR_UP	CYR61 EGR3 NR4A1 TSC22D3 RASL12 PDE2A JUNB EPHA2 IFIT1 PLK2 MFAP2 SNAI2 ELL2 NFKB2 ATF4 CYTH1 FUBP1 DDX58 KRT14 RND3 SRSF1 HIST1H2BK MMP15 RAB1A IFIT2 BCAR3 KRT19 SERPINB5 KLRC2	0.0281899	UP
RAMASWAMY_METASTASIS_DN	GREM1 ACTG2 CNN1 PLP1 NR4A1 MYH11 MAP1B ROR1 MAOB LIMCH1 MYLK ASPA P2RX1 KCNAB1 F10 NR2F2 PTN PBX2 HLA-DPB1 STAC GP1BA TAL1 CPN1 REL INPP5E RNASE1 MOS MAPRE3 AGRN ZNF646 MYL2 PRSS53 RORB ZNF148 CHRNA5 RANBP3 RBM5 CACNA1E RAB30 JMJD1C SLC10A3 NOS2 FXN HNRNPF MT3 FCAR ZNF212 ABLIM1 RUNX1 NCAPH PGK1 RNASE4 VAPB DLG3 PRKG2 CA12 SPA17 CPM ACADSB PDE6A	0.0284004	UP
BIOCARTA_MITOCHONDRIA_PATHWAY	CASP7 CASP6 ENDOG CASP3 AIFM1 APAF1 XIAP BAK1 CYCS BAX BIRC2 CASP8 BIK DIABLO BID DFFB CASP9 BCL2L1 DFFA BIRC3 BCL2	0.0285522	DOWN
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY	FOS CR2 AKT3 CD79B JUN FCGR2B CD81 CD19 CD79A RASGRP3 INPP5D PIK3CD BTK CD72 NFATC1 PRKCB RAC2 CD22 PLCG2 NFATC4 DAPP1 PPP3CC PIK3CG VAV1 PTPN6 PIK3R3 NFKBIA LYN PPP3CB PIK3CA RELA MALT1 NFATC3 AKT2 IKBKB NFKBIE AKT1 PIK3R1 RAC3 IKBKG PPP3R1 PIK3R5 IFITM1 HRAS PIK3R2 VAV2 RAF1 MAP2K1 GRB2 PPP3CA NFKBIB NFKB1 SYK RAC1 MAP2K2 NFAT5 BCL10 MAPK3 SOS1 BLNK GSK3B KRAS SOS2 CHUK PIK3CB MAPK1 VAV3 NRAS CHP2	0.0288606	UP
REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	CFD C3 C1QA C1S C1QB C4A C2 MASP1 MASP2 MBL2 CRP CFB	0.0294963	UP
TAGHAVI_NEOPLASTIC_TRANSFORMATION	FOSB FLNC PDGFB MAP3K3 AGRN RAF1 LPAR2 MCF2L HGS ACTN4	0.0297897	UP
LIU_IL13_PRIMING_MODEL	FOS EGR1 EMP3 PLK3 ETV5 JMJD6 RAB5B JAG1 GPATCH1 CHMP4A ZNF264 CDYL EGFR CLCA1	0.029984	UP
LABBE_TGFB1_TARGETS_UP	CYR61 PTGS2 CTGF ACTG2 ELAVL4 ZEB2 FBLN2 QKI BHLHE40 ROBO1 CPE JUNB VIM GRIK2 TCF4 BTK ST6GALNAC2 PDGFB SOX11 GPC1 HBG2 SERPINE1 SGK1 ITPR2 SH3PXD2A PRTN3 AIRE NUPR1 PRODH2 IL13 PTPRN IL11 NCOA1 OPRK1 HTR3B FURIN AASS ALOX15B ACOT9 ZNF35 HSD3B1 ADD2 ITGB1 ACTB GREB1 POLR2B TSC22D1 KIF5A CTSE JAG1 MTNR1A BMP1 TMSB4X PDGFRA HOXD12 PDGFA AK1 HSPA8 GADD45A IQGAP1 GADD45G CITED2 B4GALT1 PLG GIF HSPA4 SMAD7 ASS1 RCN2 SIDT2 HIVEP1 SAT1 CAPG TGIF1 SLC9A1 CAST LOX KRAS HAPLN1 UNC13B CAPN2 HOXA10 LITAF PLIN2 ABCG1 MTCH2 KRT18 KRT8 KCNK5 LAMB3 HMGA2 OTC	0.0300886	UP
MARSON_FOXP3_CORE_DIRECT_TARGETS	TNFRSF9 POU2AF1 ITK UCP2 CD2 GPR171 DUSP6 MYC ZAP70 IRF8 MAPRE2 PTPN22 GADD45B JAK2 IL2 S100A6 TGIF1	0.0301047	UP
FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP	TPM2 FLNA TUBA1A AEBP1 SELL SPOCK2 CHI3L2 TIAM1 VIM LAPTM5 SNRPN MAD1L1 CLEC2B TCF4 DMPK GATA3 CTSH SLC7A5 CD34 CX3CR1 IFITM2 LCP2 TCF7 FGR CD3E TNFAIP3 PTPN6 IKZF1 MME BIN1 FUT7 GPSM3 GDI1 BMI1 PXDN CLCNKA PRKAR1B ELAVL3 NUCB2 RALGDS RELA TLE4 IL2RG WAS CCR9 BTG1 USF2 DDX5 CDH4 DSTN ADCYAP1 PLEC CBX3 ALPP STAT3 CD47 SSR4 MYOM2 TSC22D1 SPTBN1 HYOU1 SERINC3 HLA-E G6PD CBLB CREB3 FKBP2 PRDX1 IL32 CAPRIN1 SREBF2 NRIP1 ID3 AKAP1 MBOAT7 PRDX2 SMAD1 SLC35B1 FCGRT MRPS12 VDAC1 PRSS3 NFIL3 LPCAT3 HOXA9	0.0301161	UP
BIOCARTA_ETS_PATHWAY	FOS JUN CSF1R ETS1 SIN3B NCOR2 CSF1 RBL1 E2F1 HDAC5 E2F4 RBL2 HRAS ETV3 HDAC2 ETS2	0.0301188	UP
LIANG_SILENCED_BY_METHYLATION_2	PTGS2 UCHL1 THBD HBEGF C3 MCAM S100A4 CXCL2 OAS2 C1S IFI44L IFI44 ICAM1 IL6 STC1 IFI6 MX2 TNFAIP3 CCL20 AREG INHBA IFIT1 DHRS2 MX1 MAGEA12 CSF2 MAGEA4 KRT17 DAZL IRF7 SP100 XAF1 CCL5 SERPINB2 STAT1 CXCL5 PI3 IFIT3 IL13RA2 BIK NT5E SOD2 CXCL6 IFIT2 LCN2 HIST1H2BE SLPI TNFSF10 MMP1 STX3 HIST1H2AC OAS1	0.0301301	UP
DORSEY_GAB2_TARGETS	CRYAB AKAP12 CD69 COL6A3 COL1A1 GNG11 SPARC ARHGAP25 TNFRSF9 PRSS1 STC1 CD44 DUSP5 SERPINE1 ACVR1 GSN GRIK1 TFPI2 ITGA2B ITGB3 HSD17B1 MT4 THBS1 SMAD7 IL13RA2 ATP1B1 REN PHLDA2 GK PRSS3 CCRL2	0.0301364	UP
GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP	CYR61 FOS EGR1 CTGF ATF3 ENO2 TNC C8orf4 PRKCDBP HBEGF CD93 DUSP14 BNIP3 PFKFB3 C10orf10 ZFP36 PALLD CRTC3 RGS16 GATA3 SRGN ZBTB20 NAP1L1 DNAJB4 RPS6KC1 CXCL1 CDC42EP3 CD44 RUSC2 VWA1 MPP2 HOMER1 DUSP4 ANGPTL4 ATP7A PNRC1 RBPJ ETS1 MERTK SGK1 RORA NFKBIA PHLDA1 TM4SF1 PLK2 SOX2 PPRC1 PGF KLF6 CDC42SE1 FAM49B RNGTT MAP3K1 SPRY2 JMJD6 WSB1 DDX39B SERTAD2 PTGER4 SMOX JMJD1C PTCH1 RND1 ARL6IP5 PGAM1 CNOT7 KIF5A JAG1 MAGED1 SPRY4 P4HA1 VHL PDPR ANKRD1 INSIG2 VEGFA ZNF330 TRAF6 TPI1 SIAH2 LRP5 PDK1 XPNPEP1 SDC4 PSMC4 RARS BCL10 CLCN5 PGK1 SAT1 ANXA2 TGIF1 NEDD4L SLC2A1 KLF4 SLC19A1 RPS6KA5 ACAP2 SPAST RCAN1 NAGPA IL13RA1 ARHGAP5 CHIC2 EDN1 MXI1 FAM162A ME2 SLC37A4 NEDD9 AIMP2 GBE1 MXD1 HIGD1A NDRG1 MAPK6 LXN AFG3L2 RCOR1 SELENBP1 HK2 GPRC5A SOAT1 APPL2	0.0301472	UP
WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_UP	MN1 CDKN1C ANGPTL2 LIMCH1 FBN1 NOL3 EDIL3 TXNRD3 PCSK5 HS2ST1 LRP6 PLXNB1 LRP5 ICA1 STK39	0.0301544	UP
DAZARD_UV_RESPONSE_CLUSTER_G2	CTGF ATF3 NEFM TUBB2A JUNB CXCL2 CSRP1 LY6E IER3 BAMBI CCL20 SGK1 JUND ATF4 UBE2S CXCL3 PMAIP1 INSL4 TACSTD2 HIST2H2BE TSTA3 GADD45A CITED2 PSMD8 HIST1H2AI PHLDA2 TOB1 CLDN4 HIST1H2AE	0.0305223	UP
REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	FERMT2 FLNC ACTN1 ARHGEF6 PARVB PARVA ILK LIMS1 TESK1 ITGB1 VASP RSU1	0.0305365	UP
SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER	CTGF ATF3 NOTCH3 HBA1 CDKN1C SERPINI1 ANGPT1 EREG PHC1 MAGED4B PER1 UCP2 GDF15 NGFR STC1 AREG GAGE6 TFPI2 SPANXA1 DHRS2 WNT4 CACNA1G GAGE1 ULBP2 GAGE4 EGR4 GAGE2C GADD45B FOXN3 CGREF1 ING1 GAGE12I ID2 CDH8 KLK12 MBD1 NPRL2 SSX1 BIK ADM CHFR CLDN15 ABCB1 HMOX1 MMP1 HIST1H1C CAPN5 HPSE	0.0306487	UP
HUNSBERGER_EXERCISE_REGULATED_GENES	EGR1 SCG2 EGR2 CADM1 IL16 NRTN SYN1 MFGE8 DUSP6 NPTX2 NTRK2 SLC6A1 CSF3 ODC1 GIT1 ELK1 EGR4 VGF GABRR1 GRB2 GAD1 MAGED1 GPR37L1 UBE2B MAP2K2 LDHA PRKCI NPY MAPK1 PCK1	0.0307493	UP
WOTTON_RUNX_TARGETS_UP	CCL2 NCAM1 CYP1B1 EMILIN1 LY6E ST3GAL5 ANGPTL4 TIMP4 MASP1 UGCG CCL7 ITGB5 CDK18 RNF19B WWP2	0.0307816	UP
YAGUE_PRETUMOR_DRUG_RESISTANCE_DN	TNS1 CALD1 DCHS1 NTM DSE LTBP2 MMP2 ACAN FRMD4A VCAN COL8A1 TRAM2 SEPT11	0.0309905	UP
LU_IL4_SIGNALING	EGR1 CTGF PEG10 CD69 VEGFC MAL SELL BHLHE40 CD79B BCL6 HLX AKAP2 SAMSN1 EVI2A RASGRP3 NCF2 HLA-DRB5 CD86 IL6 CCL4 FGL2 SLA ZBED2 TNFAIP3 KMO IL2RA BATF FCER2 AGER CNTN6 VCL ALOX5 MTMR9 HOXC4 IRF8 WT1 RGS6 SOCS1 SMARCA2 STAT4 RRAGD ATXN1 RPL5 TLR7 GNAS PHF20L1 STK4 CCL5 NCOA3 IL4R MARCKSL1 MAP3K5 PMAIP1 HUWE1 RPS2 QSOX1 EIF4G1 PPP2CA CFLAR CISH CMTM6 BCKDK PPP6C MRPS15 ARPC5 SLC15A2 CLTC XBP1 SIAH2 VMP1 ARAP2 SEL1L3 MGLL CTSD PKN2 LY75 KLF13 SPINT2 NFIL3 GSR TNFRSF11A SPAG1 APPL2 TLR3	0.0310363	UP
ZHOU_TNF_SIGNALING_4HR	CYR61 CCL2 TGFBR3 ELOVL5 FBN1 ITGB2 TNFAIP2 CLIC4 CXCL1 PTGES KIT NFKBIA SF3A3 SMARCE1 PPP1R10 KEL NCL RPL10 RPS8 ITGB1 EEF2 TPR RPL27A RPS23 FAM50A ACLY KALRN MYL6 TUBA4A OAZ1 SHFM1 GDI2 PSMB7 CDC34 PCMT1 CD59 GADD45A PRDX1 NFKB1 DROSHA PLP2 IL32 MYL12A CCNC GINS2 SOD2 TNIP1 TSPAN3 CMPK1 PSMB8 EBP MAN2A1	0.0312075	UP
LANDIS_ERBB2_BREAST_TUMORS_324_UP	ETNK1 EHF TGFA CMAS GALNT3 SMAGP TOM1L1 ERBB3 FLVCR2 PERP CLDN7 DSG2 F11R TUFT1 IRF6 VDR KRT8 FXYD3 ANK3 STK39 LXN TSPAN8 SPINT1 CHEK1 EPCAM WWC1 SLC12A2 EBP AIM1 CTNND1 CHMP2B F3 LSR TPD52 ORMDL2 TMED3 ANKH WSB2 CRADD LITAF CLDN3 LCN2 UNC119B CD9 FLNB SOX4 PDIA4 CYB561 ATP6V1A IGF2R CDK1 DAP TRAF4 EZR SOCS2 CTSC ACTN4 RCN2 ST6GALNAC4 XBP1 PPP1CB PQLC1 FAM134B LMAN1 SERINC3 PTPN2 ZC3H15 ATP6AP2 SERP1 PPP3CA CALM2 NDST1 SKP1 RRM2 GOLPH3 ATP6V1E1 ID2 KCNN4 LIG3 FOLR1 MLH1 SRP19 WEE1 CTBP2 DCK SS18L2 DOK1 LRRFIP1 SPTAN1 ELL2 CD82 FBXW7 INPPL1 B4GALT6 DDX6 FUT8 HOMER2 PAPSS1 NUCB2 ITPR2 MAPK8IP1 ALDOC FGD1 PTK7 LMO4 CXCL1 CCND1 DUSP6 IER2 IER3 ETV1 PITPNC1 TFAP2C ST3GAL5 TPD52L1 ENAH SLC29A1 CSRP1 ACSL4 TIAM1 NR4A1 AKAP12 BAG2	0.0313266	DOWN
FARMER_BREAST_CANCER_CLUSTER_4	SRD5A1 PDZK1IP1 STEAP3 MALL NAMPT NDRG1 VLDLR SLC31A1 EGFR ADM AGFG1 CLDN1 MPP6 PEX3 KYNU	0.0313299	DOWN
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP	GUCY1A3 MEIS1 TIE1 FHL1 KANK2 SNN ANGPT1 JAM3 ROBO1 NEFH NUDT11 CD200 NPR3 IFI16 LY6E ARID5B FSCN1 MACF1 TAF9B ISYNA1 KLHL26 CDK6 MEF2C TAL1 CDK17 HSPB1 TM4SF1 CRHBP CYP1A1 MPL BCAT1 TERT DDX39B MTSS1 MARCH6 TMEM5 H3F3A TMEM176A ALDH1A1 TFAM ID1 F2R SOCS2 TMEM176B SOX4 HSPE1 MECOM ALDH5A1 DNAAF2 JUP GK IL17RB GNAI1 F2RL1	0.0316615	UP
REACTOME_STRIATED_MUSCLE_CONTRACTION	DES TPM2 DMD VIM MYBPC2 TNNT2 TNNT1 TCAP TPM1 MYL3 ACTN2 TPM4 MYH3 TNNI3 MYL2 TNNI2 MYL4 MYL1 TPM3 MYH8 TNNC1 MYH6 MYBPC1 NEB TNNI1 TNNC2 TMOD1	0.0316849	UP
VALK_AML_CLUSTER_10	CHRDL1 TPM2 RBPMS MN1 CFD SNED1 SETBP1 SPRY1 BAALC ARHGEF17 CD22 PPP1R16B EEF1A2 C3AR1 BCL7A NPDC1 SORBS3 CRIM1 PRKD2 SPTBN1 RNASE2 AZU1 PIK3C2B PAWR FLNB MLLT3 SPON1 GNAI1 F2RL1 SMAGP	0.0320057	UP
REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC	SAR1B ERAP1 SEC23A SEC24B TAP2 PDIA3 HLA-F HLA-A TAP1 HLA-B CANX SEC13 HLA-G HLA-C CALR SEC24D B2M HSPA5 SEC24C SEC31A	0.0321382	DOWN
TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN	ITPR1 CD37 MS4A1 RHOH HHEX LTB BLK TRIM22 CD83 GIT2 GPR18 CXCR5 HLA-DMB MMD TGFBR2 LYL1 BIN1 CIITA REL SATB1 AHR IRF8 CCND3 MAPRE2 RHOG NFKBIE MOB1A IL4R AXIN1 IFNGR1 LPGAT1 NFKB1 KIAA0430 RPS4Y1 ELF4 GCH1 AIM1 SERPINB1	0.0325391	UP
GUO_HEX_TARGETS_DN	TFPI PTRF TIE1 CDH5 LPL ADAM19 CD93 ACTC1 IGF1 ENG F10 CLDN5 NFATC1 RAMP2 FMO1 FLT4 SOX18 IFITM3 EPB42 STAB1 GATA1 KLF1 ANGPT2 MED1 MEA1 RHAG SLC4A1 ACTB GSTM2 ARL6IP5 PSME1 KPNA1 FXN UROD CREG1 LIG1 MBP POLR2J PTTG1 GDAP2 GFI1B NET1 RALY SOD2 ACP1 DCTPP1 LMNB1 CSNK2A1 PIP4K2C BMP2K GSTK1 SLC39A8 TOM1L1	0.0325665	UP
SEKI_INFLAMMATORY_RESPONSE_LPS_UP	EGR1 EGR3 CCL2 C8orf4 EGR2 PRRX1 VCAM1 EREG CCL3 MAFF SLC15A3 CXCL2 TNFAIP2 OSMR NGFR ICAM1 IER3 CXCL1 CD44 CD40 SLC4A7 SELE TNFAIP3 RFX5 REL NFKBIA RIPK2 PLK2 GPR68 ADAMTS7 FOSL1 BIRC3 CSF1 NFKB2 GBP2 CASP4 BTG1 NFKBIE TLR2 SLCO4A1 GBP1 GADD45B STX11 CXCL3 ICOSLG CXCL10 LIF RND1 CCL7 ZC3H12A PTPRE BIRC2 EGFR SOD2 TNIP1 CXCL6 FAS PLSCR1 RAB20 SLC11A2 GCH1 TMEM2 BMP2 CCRL2 TJP2 RSAD2	0.0326799	UP
FERRANDO_TAL1_NEIGHBORS	BCL2A1 ITGB2 CSF1R IL23A LCK CD2 FCGR3B TCF7 TNFRSF1B CD3E TMSB15A CD6 MYBL2 FOLR1 DTYMK CXCR1 RUNX1 CRIP1 LGALS3 CDA	0.0327125	UP
REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	MYL9 MYH10 MYH11 RHOB PTPRC CD72 RAC2 RRAS SEMA4D LIMK1 RHOG ROCK1 RND1 MYL6 MYH9 RHOA PLXNB1 ARHGAP35 MYL12B RAC1 CDC42 ARHGEF11 ROCK2 ARHGEF12 MYH14 ERBB2 MET LIMK2	0.032715	UP
SCHUHMACHER_MYC_TARGETS_UP	AUH SLC16A1 MEST CYP51A1 SLC39A14 UCK2 SLC20A1 NAMPT AHCY UCHL3 SORD GPD1L SRPK1 AIMP2 TMEM97 TFRC FABP5 MXI1 HSPE1 CYCS PRPS2 PAICS GCSH GRSF1 EBNA1BP2 ATP1B3 AKAP1 LDHA FKBP4 CTSC RPIA PRDX4 POLR2H AK4 TRAP1 MTHFD1 MRPL3 DDX21 RCC1 VARS DCUN1D4 ACSL1 RABEPK PYCR1 PEBP1 POLD2 FASN FXN VRK1 NME1 TARBP1 IMPDH2 CEBPZ ABCE1 ZNF239 DHODH IARS NOLC1 EXOSC2 PNO1 RANBP1 CAD RRS1 BOP1 CDK4 TBL3 EXOSC7 PPAT RRP1B ODC1 LRP8 DDX10 SLC39A6 MYC SRM NEFH	0.0329687	DOWN
VILIMAS_NOTCH1_TARGETS_DN	ITGAM CTSG CSF1R CMA1 NCF2 BTK NCF4 STOM CSF3R CAMP CSF2RA PGLYRP1 MATK VPREB1 GFI1 MPO TREM2 GFI1B	0.0329975	UP
REACTOME_M_G1_TRANSITION	GMNN ORC2 PSMC6 CDC6 CDC7 PSMB8 ORC5 PRIM2 ORC4 PSMD3 PSMA5 PSMD7 MCM4 PSMD13 PSMB10 CDT1 PSMD10 ORC1 MCM2 PSMD11 PSMA3 PSMC4 PSMD8 RPA3 PSMA6 POLE2 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 E2F2 POLA1 PSMD2 PSMB5 ORC6 PSME4 PSMD14 PSMB6 MCM7 PSME2 PSMD12 PSMB1 DBF4 PSMD6 PSME1 E2F3 PSMB4 PSMB9 PSMB2 MCM10 RPA1 PSMC2 PRIM1 PSMC5 CDC45 PSMD4 PSMC1 ORC3 CDK2 MCM6 RPA2 RPS27A POLE MCM5 RPA4 UBA52 MCM3 E2F1 POLA2	0.0335612	DOWN
BIOCARTA_DREAM_PATHWAY	FOS JUN PRKAR2B CREM PRKACG PRKAR1B PRKAR1A OPRK1 POLR2A CREB1 PRKAR2A MAPK3 PRKACB	0.0340852	UP
ZHU_CMV_8_HR_DN	GAS1 ADH1B TFPI MN1 TGFBR3 FBLN1 FGF7 RBMS1 ENG DDIT4 NR3C1 CEBPD NR2F2 ZFP36L1 CDC25B IL6ST LDLR AR APOE AHR AARS RALGDS USP4 TFAP2A TFAP4 TP53BP1 WEE1 LMNA TNFRSF1A ITSN1 ANAPC1 ERCC5 ID2 BMP4 MYH9 IGF1R ANP32A RUNX1 ADM MAPK14 TCF7L2 MARCKS AKR1C1 ACVR2A ACO1 IGFBP2 MMP1 HNMT ADRA2A	0.0341094	UP
PID_NFAT_TFPATHWAY	FOS EGR1 PTGS2 EGR3 EGR2 JUN JUNB CREM GATA3 NFATC1 PRKCQ IKZF1 BATF3 IL2RA MAF IRF4 CD40LG CTLA4 POU2F1 FOSL1 IL3 SLC3A2 FOXP3 TLE4 NFATC3 CSF2 E2F1 CDK4 FASLG DGKA EGR4 IL5 PTPN1 TBX21 IL2 IL4 IFNG CBLB TNF PTPRK ITCH CASP3 PPARG RNF128	0.0341561	UP
LI_INDUCED_T_TO_NATURAL_KILLER_DN	OLFML3 ACTA2 NOTCH3 CXCL12 RAMP1 TRIB2 C3 PRELP ARHGAP15 CD81 TPST1 ACTN1 SLC29A1 COL6A1 CD27 BGN CD2 RAPGEF3 PRKCB HDAC7 ABHD8 TCF7 CD3D TACC1 RGL2 MSH6 SH2D1A COL5A1 SLA MMP2 ART4 ANP32E BCL7A CD6 NISCH ETS1 SATB1 ITPR2 FYB TSPAN32 CTLA4 LDHB LLGL1 TRIM28 GLDC ENDOU PDLIM4 ACVR2B BRD3 COX6A2 CD8B TXNIP POU6F1 BCL11B TBXA2R DGKA GFI1 RRP12 ST6GAL1 LY6D STK4 LMAN2L SETD1B DNTT TTC3 RNPEPL1 NCK2 TPCN1 XRCC6 DAP3 MTF2 ETS2 EPHX1 DPP4 PDK1 LOX ILVBL MARCKS SOX4 PRKCD ALDH2 CHCHD3 RMND5A MAPK1 FBP1 IL17RB CRYL1 SLC16A5 FRAT2	0.0342826	UP
MCGARVEY_SILENCED_BY_METHYLATION_IN_COLON_CANCER	UCHL1 SFRP1 EFEMP1 FBLN2 DKK3 SOX17 JAM3 CHL1 ICAM1 INHBB SFRP4 SFRP5 LEF1 EPHA4 DDX43 EYA4 POMC TFPI2 INHA GATA4 FOXL2 ASCL2 GSTM3 CABYR JPH3 CHFR CTAG2 RAB32 CBR1 HOXD1	0.0345054	UP
WU_ALZHEIMER_DISEASE_DN	NR4A2 PDE1A ELN HSPA2 FADS2 ADAMTS2 MAF PDE1B NUPR1 DEFB4A EIF2S3 PLEC REM1 IFITM1 RPL37A CDK10 CD2BP2 ANK3	0.034694	UP
NAKAMURA_METASTASIS	NRN1 TUBB6 AXL SCRN1 BLVRA TUBB2A HCLS1 LAPTM5 PRKCB ETV1 ACD PADI3 NTRK2 GGA2 TMX4 PCDH8 FOSL1 DDX24 DUSP3 SMYD3 AKAP13 GLUL HS3ST1 FKBP10 PDE10A XCL1 SF3B3 MEPCE NKX3-1 KRT13 STX4 SOSTDC1 SLC16A3 PGK1 MRPS6 PDK3 SLC12A2	0.0347734	UP
KIM_WT1_TARGETS_12HR_UP	MYL9 FERMT2 TIMP3 ENO2 ID4 ZCCHC24 MN1 PLEKHO1 GPR183 HTRA1 HBEGF TRIB2 FZD7 MYBL1 ATP2B4 LBH HEG1 ST8SIA1 RHOQ PEA15 MYLK CHRNA3 FGFR1 JUNB THY1 CSPG4 PODXL SH3BP5 CX3CL1 PRKCH AQP1 GRB10 HSPA12A GDF15 DDIT4 CDR2L HSPA6 FAM65A DAB2 CDC42EP3 SERPINH1 TULP3 AREG SERPINE1 FGF1 PIK3R3 GLI2 AAK1 SLC17A7 FHOD1 RBFOX2 KIF3C SUPT6H IFIT1 CREB3L2 TM4SF1 CSDC2 PLAU SNAI2 AMPD2 YPEL5 WT1 KLF9 RAB13 CSF1 SEPT9 HNRNPL MYCN MICALL1 IL11 CALCOCO1 TPST2 ADORA1 SYNC ULBP2 SCNN1D TAF6L SRSF6 MSX1 EPOR NOX4 BLCAP KIF5B MED13L BHLHE41 NYNRIN HHLA3 TMPRSS3 SON MYOF ARHGDIA SLC10A3 PJA2 COPB1 TUBA4A MGEA5 NPPB TLE3 ZMYND8 IL1RAP ZNF395 PDGFRA CDC42EP4 MTDH HSPH1 PPP3CA ACSL1 P4HA1 HSPA1A CRY1 ZMIZ1 SMAD3 CXCL14 UBE2J1 ITGB5 TBX3 PLAT TNS3 GGT1 RASSF7 PLCD1 DNAJB1 NFAT5 ADM CS FGFR3 TLN2 CREB3L1 TNFRSF11B VPS37B MTUS1 ATP1B1 ENDOD1 BAK1 DDR1 P4HA2 CASK SOX9 CHRNA1 DOK4 EPS8 SLC20A1 CA12 ATP9A IL10RB KCNK1 DLGAP5 OXR1 RUNDC3B TBC1D2 ABAT GFPT1 LGR4 LRP4 PSD3 C1orf116	0.034819	UP
LEE_AGING_CEREBELLUM_UP	FOS THBS2 NR4A1 BCL2A1 CCL21 TGFBR3 AXL SPP1 PTBP2 GABBR1 GNG11 C1QA HLA-DQB1 EFS CTSH C1QB SNTA1 HOXA4 BDNF GNA15 PTPRO APOE IFIT1 SELPLG TBC1D1 NOTCH1 OR2C1 SF3A2 PGLYRP1 NOS3 GCK RHOG CST7 MNAT1 CDK4 IRF7 EPS15 TBX6 IARS CD68 MYH8 SLC11A1 F2 HNRNPH3 UBE2H RPSA NFYA B2M GNB2 EIF2B5 EPRS HOXD12 GFAP CTSZ RAD21 DNAJB2 HSPA8 ACADVL ITGB5 PIGF TYMS WDFY3 HEXB LMNB1 APC LGALS3 LGALS3BP IMPA1 CTSD CAPN2 CD24 CTSS IFI27 HMOX1 AGT	0.0349421	UP
SMITH_LIVER_CANCER	DDC AMACR GSTM4 IMPA2 HTATIP2 AURKA TOP2A PIR SEMA5A RAB4A SDHC RHOBTB3 PEX2 CENPF TOB1 CDKN3 NCOA2 PGRMC1 FDPS TBCE PPP2R5A TMEM106C MTFR1 COPS5 TBX3 ALDH1A1 HJURP ANXA7 PAK4 PFDN6 NHP2 PMVK ACACA TP53BP2 PDCD5 GSTA4 BMI1 SHCBP1L TNFAIP3 BNIP3 CTNNA2 SDC2	0.0349847	DOWN
HUTTMANN_B_CLL_POOR_SURVIVAL_DN	SOBP EGR3 BACH2 BANK1 AKT3 MYBL1 EAF2 ADARB1 VNN2 ZNF532 ALCAM FCRL2 GLIPR1 ZBTB20 PLAG1 TCF7 METTL8 RECK STAG3 SLC4A7 DGKG MEF2C NUCB2 UTS2 FUT8 ATP10D BIRC3 SLC4A8 SLAMF1 ADAM29 ABCA1 FRS2 USP6NL ZNF652 ZNF280D MTSS1 PTK2 CNTNAP2 EIF4G3 COBLL1 SOCS5 MAP2K5 ADK ADAM10 NRIP1 ADAMDEC1 SMC5 SYNJ2 ATP1B1 RRAS2 HELLS CASP1 TPD52 ATP2B1 PDE8A PIP5K1B	0.0353811	UP
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9	TMOD3 ANPEP RAB25 SLC1A1 EMP1 TST CBR1 TMPRSS2 KRT19 FXYD3 LXN TSPAN8 ITCH VAMP8 CASP1 CD24 PON2 ELF3 PRKAB1 EYA2 LGALS3 PSMB8 MARCKS NFE2L3 PPM1B HES1 PAX8 NUDT4 CTSC SURF1 MAN1B1 PKP4 GSTO1 AKTIP SDCBP H2AFV PSMB9 OVGP1 IRF9 DBNDD2 RPL36A UPK3B NFIB NSA2 IRF7 EIF3E MNAT1 CD99 GSTA4 DLX6 FAM3C PLA2G4A TES ISG15 AHR PFDN2 S100A13 IFIT1 A4GALT MDFIC CD83 CD53 TYROBP SDPR	0.035616	DOWN
WILSON_PROTEASES_AT_TUMOR_BONE_INTERFACE_UP	TIMP3 SERPING1 MMP9 CTSG CTSK SERPINE2 MMP13 USP32 MMP12 USP1 USP14 USP15 SERPIND1 USP53 USP24 USP33 USP16 USP25 ADAM10 ADAM9 USP2	0.0359086	UP
LU_TUMOR_ANGIOGENESIS_UP	CXCR4 SPP1 MMP9 FGFR1 FYN JAG2 STC1 CD44 TNFAIP6 FGF18 CCND2 NOTCH1 TYMP CCNE1 VCAN HEY1 PTK2 VAV2 E2F3 JAG1 ITGAV PDGFA VEGFA EDN1 EZH2	0.0359667	UP
MULLIGHAN_NPM1_SIGNATURE_3_DN	GUCY1B3 GPM6B FHOD3 MYH11 COL14A1 PLEKHO1 PDE4B TPPP3 RUNX1T1 FHL1 SCRN1 ITGA5 PDE2A HEG1 FXYD5 SERPINF1 FGFR1 CD200 NPR3 ARL4C PPM1F HLA-DQA1 MRC1 CD34 ZNF135 MAP4K1 PPP1R16B TCF7 SOCS3 SVIL PDE4D DENND3 HSPG2 ATP10A TGFBR2 ZNF467 DUSP5 INSL3 ABCD1 LTBP4 CNN2 VAMP5 ESYT1 PLCG1 FCER2 LDLR HGF CHST7 PRAME SNRK PABPC4 HSPB1 RNF130 EHD1 LAX1 HOXC4 EEF1D CSNK2A2 BTN2A2 CAPN3 RETN SUN2 CD7 SPTAN1 POU6F1 RPL4 ARID3B GJB3 HPCAL1 PI4K2A PDX1 ZNF384 DEFA4 BCAT1 EIF3D OAZ3 LPAR6 RRP9 MEF2A TNFRSF25 RNFT2 PLEKHG3 MOB1A RYR1 IFITM1 DRG1 RARA GPR6 RPL28 EIF3F ADAR ACLY SPTBN2 AQP4 MLNR PMAIP1 TCEB1 ZNF287 CERS2 GAD1 FLAD1 GRHPR UBE2L3 RERE TERF2 DGKD ZC3H15 PES1 GDI2 TTC21B NBL1 LRRN2 PHB2 UXT FAM134B DSC1 DDO EFCAB1 SIPA1L1 MPHOSPH6 GNAQ NFYC QARS EIF6 PSMA6 PSG9 COPS5 XPNPEP1 LDHA EPHB2 TUFM KCNQ1 CS GPI KATNB1 PYGB RAB11A ABCG5 CAMKK2 FAM171A1 NIT2 HOOK2 ST14 ABCG1 TRPM4 PCSK6 RAB4A SLC9A3R1 ATP9A TSPAN7 TMPRSS2 PLCB4 EPHX2 LRP4 SLC9A2	0.0360011	UP
CARD_MIR302A_TARGETS	ZFPM2 HLF MAP1B SLITRK3 JUNB ASAP1 ZFHX4 SASH1 TWIST1 ZHX2 NR2F2 STC1 CCND1 TNFSF11 SOX11 TGFBR2 CDK6 EPHA4 RARB CCND2 MNT ARID4B FOXJ2 KLF9 LIMK1 EFNB3 MYT1 E2F1 RORB DNMT1 CDC37L1 DDX5 E2F5 RBBP6 FOXG1 KAT6A RBBP7 PHTF2 CDK2 WEE1 NEUROG2 RBL2 PFN2 IKZF2 STAT3 ARID4A RIC8B RBBP4 RB1 CNOT7 CLOCK EIF4G2 FBXO21 NEUROD1 SRSF2 PPP6C VEGFA KPNA2 RB1CC1 TARDBP SMAD7 FOXJ3 MBD2 RAB5C RNF6 CCNG2 VLDLR YES1	0.0362289	UP
RIZ_ERYTHROID_DIFFERENTIATION_12HR	FOS EGR1 PTRF HAND1 PBX3 JUN PAX5 PIAS3 HAND2 ARNT2 NAB2 NDN HIC1 HOXA4 SIX6 AR SATB1 SPIB NOTCH1 ZFP37 KLF9 ZNF22 POU6F1 HDAC5 KLF6 DLX5 FOXB1 TEAD1 ESR1 PAX9 TSC22D1 BACH1 KEAP1 SMAD1 HR MLLT3 NR1H3 IRF6 TFCP2L1 GATA6	0.0368827	UP
BIOCARTA_NGF_PATHWAY	FOS JUN NGFR PIK3CG NGF PLCG1 PIK3CA PIK3R1 ELK1 HRAS MAPK8 SHC1 RAF1 MAP2K1 GRB2 MAPK3 SOS1 CSNK2A1	0.0369129	UP
REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE	SYT1 STXBP1 SNAP25 VAMP2 RIMS1 RAB3A STX1A SLC18A2 SLC22A2 MAOA	0.0369322	UP
PID_PDGFRA_PATHWAY	FOS CAV1 JUN SRF PLCG1 PIK3CA JAK1 PIK3R1 ELK1 SHB CAV3 RAPGEF1 SHC1 GRB2 PDGFRA ITGAV IFNG CRKL SOS1 CRK CSNK2A1	0.0369677	UP
SHIN_B_CELL_LYMPHOMA_CLUSTER_3	ZEB2 CXCL13 CADM1 TGFB1 HHEX LCK LTB NFATC1 CD86 CCND1 FGR BCL2 MAF LRMP CCND3 CXCR6 LFNG NFKB2 FZD1 TNFRSF1A CBX5 ID2 JAK2 IL2 NFKB1 TNFSF13 WNT5A IL18	0.0370009	UP
WILENSKY_RESPONSE_TO_DARAPLADIB	MMP9 CD48 EVI2A EVI2B UCP2 HLA-DMA CD4 CCR1 CCR2 CYBB NCF1 PTAFR PLA2G7 ARRB2 LAIR1 GM2A BIN2 PLAUR CHI3L1 CXCR3 CD68 CCL5 LTBR IL1A DENND2D NPL CTSS HMOX1	0.0370234	UP
BOYLAN_MULTIPLE_MYELOMA_PCA3_UP	UCHL1 PCP4 ATF3 TFPI CD69 KLF7 BHLHE40 TRPS1 JUN ISL1 PLLP TSPAN4 ALCAM ENAH GPR65 SLC47A1 RET CCND1 BHLHB9 KIF13A CDK6 GRIK1 SHCBP1L CCND2 DNAI2 PLK2 TRMT61A PLA2G4A COX6A2 RRAGD ATXN1 KCNF1 BCL11B ACOXL VOPP1 CCDC91 ASNS RAB30 UPK1B LGALSL ABTB2 CKB RNF125 PRSS23 OBSCN MT2A CDC42BPB NRIP1 LAPTM4B TLN2 SMAD1 CERS6 FABP5 RAB20 GPHN RNF43 PIK3CB SLC30A1 SERPINB1 TMEM38B PPARGC1A	0.037477	UP
IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_UP	DMD TUBB2B FN1 FAM189A2 ZNF337 APOB SULT2B1 PCBP3 CNBP S100A2 MT4 PTPN18 ZFPL1 RNF103 RMND5A	0.0378441	UP
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_DN	GAS1 AOC3 FERMT2 CFD IGFBP6 C3 SORBS1 SPARCL1 COL1A1 S100A8 EHD2 CD52 BHMT2 CBX7 C5AR1 ATP6V0E2 RAMP2 CALU FGR ZFP36L1 MAGI2 IFITM3 COL3A1 UBE2L6 GDI1 CSF3 SH3PXD2A TIMP2 EHMT2 PFDN5 SIGLEC5 UBTF B3GAT3 IFI30 MMP14 HPCAL1 SLC2A11 TMEM231 SET ZNF593 RPL12 CST6 FAM69A RPL17 MANF RPS16 GOLGA2 RPS24 PPP2R5C LAPTM4A RPS12 GNB1 PIN1 SEPT2 RPS3A RPS29 RPS18 CD47 RPS28 KCND1 SH3BP2 RNPEPL1 CAPZB SNRPB CUTA EIF1B HDAC2 CNN3 SKP1 CPT1B PDGFRA CORO1C MAP1LC3B AP2S1 USP9X SERINC3 VARS HSPA8 NDUFB8 RAB6A CANX TXNL1 AHCYL1 XBP1 SCAND1 DENR STK24 KDELR3 DAZAP2 GLRX COX8A SREBF2 ATP5A1 TMBIM6 ATP2A2 ARHGAP26 MLXIP FCGRT COX5B LGALS3 CAT CSTB HMOX1 AKAP9	0.0379064	UP
BOYAULT_LIVER_CANCER_SUBCLASS_G2	MLLT11 MEIS2 AMIGO2 FHOD3 NAV3 ITGA5 DEGS1 MCTP1 INHBB SLC2A6 ENPP2 HIP1 ALDOC MOAP1 SDF2L1 CNPY2 RPN2 KIF14 EPHA1 SAP130 INTS7 CD58 KLHL7 RRAS2 ARHGEF40 MOSPD1 SATB2	0.0383146	UP
PID_ATF2_PATHWAY	FOS ATF3 DUSP1 CSRP2 DUSP10 JUN JUNB IL23A IL6 SOCS3 CCND1 CBFB INS MMP2 HBG2 DUSP5 SELE BCL2 ACHE PRKCA JUND PLAU POU2F1 TGFB2 ARG1 DDIT3 CDK4 DUSP8 MAPK11 HRK ESR1 MAPK8 KAT5 RB1 NOS2 ATF2 PDGFRA CREB1 BCL2L1 RUVBL2 IFNG GADD45A H2AFY EP300 CUL3 BRCA1 MAPK9 MAPK3 TH MAPK14 HES1 NF1 MAPK1 SERPINB5 CCNA2 PPARGC1A	0.0383417	UP
BROWNE_HCMV_INFECTION_20HR_DN	CTGF TFPI CAP2 FILIP1L SYT11 FRY TGFBR3 ANXA1 PDE4B AXL TMEM158 RUNX1T1 PMP22 SYNE1 AKT3 FBXL2 ROR2 COL1A2 PTPN13 FGF2 PTGFR RGS4 TRIM22 BICC1 MACF1 SVIL ST5 REV3L LPP LTBP1 VCL LRRC15 NR1D2 PKIG LILRA1 AHR FST TBC1D8 IGF2BP3 MBNL1 RHOBTB1 HOXC6 ATXN10 DST FARP1 SRPX2 TPD52L2 SERPINB2 FOLR3 MAP3K5 MGEA5 TNFRSF14 GSTO1 ITGA3 RND3 HIST1H4C TRIO ACPP KRT34 SIPA1L1 BBS4 HMBS TRAM2 ME3 F2R GLRX ADD3 DNASE1L1 ANXA2 TNKS RABGAP1L KIAA0101 ECH1 VPS41 MGLL RRAS2 CHMP2A BUB1B SEPT11 CRADD DIAPH2 RHOBTB3 GBE1 ACO1 NMT2 ACAA1 ATP13A3 ATP2B1 ALDH6A1 TRIM2 TMCO6 TRAF3IP2 ETHE1 HMMR WIPI1 NQO1 SLC22A4	0.0384099	UP
GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP	UCHL1 OSR2 LYVE1 PEG10 CHODL EGR2 GAP43 SYT11 ACTA2 CYP1B1 DAAM2 C3 ANGPT1 EPHA7 SPARCL1 CHGB P2RX5 RELN C10orf10 ROR2 CD48 SPON2 MPPED2 MXRA8 MAPT FAM49A IGF1 RAMP3 DOCK10 ARID5B LRRC49 PALLD ST6GALNAC2 RAPGEF3 EGFL7 SELP ARHGEF17 CXCL1 NDN CTNND2 CRMP1 CD40 RBP1 TMEM59L NOV NDNF GPR162 GABRE POU3F2 SRPK3 RNF122 UBD LRAT FOXJ1 CRTAM UBE2L6 PTPRO FAM189A2 DUSP22 ADAM8 PRKG1 P2RX6 OPRM1 SMG6 SIX2 NPVF ASCC1 CYP2A6 LIN7B ST8SIA5 EYA3 AQP5 NFIB TNFRSF25 KAT6A ZPBP ITIH2 MUC16 ZBTB1 METAP2 GNG4 EMID1 TTC3 CYP2F1 UBAP2 SUB1 MMP10 CSTF2T ABL1 LY6G6C NFX1 NANOG EPB41 INPP5K EIF2S1 RAB38 NCALD TMSB10 UBA6 PHF14 TNIP2 ST18 POLQ ANP32A PRMT7 NFYC ATG7 RAI14 DHRS3 APP MFHAS1 BAZ2B PLP2 THBS1 CHD1L SYT13 PDCL UGT2B4 CLCN5 ANG IRAK4 TMEM144 COG5 UBL3 KDM5D NF1 MGLL REG1B PDK2 RSU1 SNAPC3 BBS7 C1D SCUBE2 MGST2 FBN2 GDPD2 HSD17B11 ALDH6A1 CEL ATP9A TRIP11 VDR CBR1 SLC26A2 AVL9 SYTL2 CEBPA TMEM53 PAQR5 AGPS AGR2 PTPN3 PDZK1IP1 RNFT1 ADH1C	0.0384279	UP
DAIRKEE_TERT_TARGETS_DN	DNAJC6 HSPB8 CCL2 TSPYL5 PDZRN3 CALD1 EFHD1 GPX3 DYNC1I1 RAI2 OLFM1 FAM110B IGFBP7 ARHGEF26 LMCD1 BTK GATA2 GNAZ PLXND1 MACF1 KANK3 CELF2 B3GALNT1 ATP10A TGFBR2 STK32B WWC3 DACT1 PAPPA TSC22D2 EDIL3 POU2F1 ADAMTS7 CDKL2 SMYD3 DCLK2 STARD13 ZNF174 DFFA C10orf12 BCL9 MBNL1 PBRM1 PPM1H HELZ ZNF592 EFNA5 QPCT TTN SEC22A TECPR2 DYNC1LI2 CDR2 NEK7 ABTB2 SYT17 STAU2 ZIM2 FBXO21 MEMO1 BCKDHA SMYD2 SCGB2A2 USP24 UBE2J1 ANKRD1 PSORS1C1 TRAPPC8 PAFAH1B1 SLC15A2 ABCB8 DCAF13 TOR1AIP2 C2CD2L PACSIN2 ZFYVE16 HES2 RPS26 UBL3 ACAP2 FAHD2A C1orf56 SEPT11 BSPRY CEACAM7 DENND1B HGD RALGPS1 GUF1 PBLD	0.0385868	UP
KEGG_ALZHEIMERS_DISEASE	CHP2 CASP7 CASP3 PLCB4 NDUFS1 PSENEN APAF1 MAPK1 SDHB SDHC COX5A PSEN1 SDHD NDUFS2 NDUFB7 ATP5G3 CYC1 IDE NDUFA10 FADD NDUFA9 NDUFS4 SDHA NDUFB3 BACE2 ATP5D NDUFS3 ATP5B CAPN2 NDUFS7 UQCRFS1 UQCRC1 UQCRC2 ATP5G1 CYCS COX5B EIF2AK3 NDUFV1 NDUFA8 NDUFB6 NDUFC2 FAS NDUFA6 ATP5F1 UQCRQ CAPN1 APH1A ITPR3 GSK3B ATP2A2 NDUFC1 COX6A1 NDUFB5 COX7B ATP5A1 ATP5C1 CDK5 NDUFB2 COX7A2 NDUFA5 NDUFA7 ADAM10 UQCR10 MAPK3 CASP8 NDUFAB1 COX8A COX6B1 NDUFS6 NDUFA2 TNF UQCR11 COX6C ATP5O ATP5J ATP5H NDUFA1 BAD GRIN2C NDUFV2 APP UQCRH COX4I1 NDUFB4 COX7C BID NDUFB1 GNAQ CACNA1F GAPDH NCSTN NDUFS5 NDUFB8 NDUFS8 CASP9 ATP2A3 NDUFA3 PPP3CA NAE1 HSD17B10 CALM2 COX7A2L CALM3 ATF6 CACNA1S PLCB3 ATP5G2 CALM1 UQCRB ATP5E TNFRSF1A GRIN2B NDUFA4 PSEN2 ATP2A1 ADAM17 GRIN2A PPP3R1 NOS1 GRIN1 ERN1 CACNA1D LRP1 CALML3 GRIN2D COX6A2 SNCA PLCB2 IL1B CALML5 PPP3CB ITPR2 APOE CDK5R1 MME NDUFA4L2 PPP3CC CACNA1C APBB1 BACE1 MAPT PLCB1 LPL RYR3 ITPR1 COX7A1	0.0386721	DOWN
REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING	ATP5D ATP5B ATP5G1 ATP5F1 ATP5A1 ATP5C1 ATP5J2 ATP5O ATP5J ATP5H ATP5L ATP5I ATP5E	0.0386909	DOWN
REACTOME_SIGNALING_BY_WNT	FRAT2 PPP2R1B PSMC6 PSMB8 APC FRAT1 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PPP2R5A PSMD11 PSMA3 PSMC4 PPP2CB PSMD8 PSMA6 PPP2R5E PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PPP2R1A PSMD2 PSMB5 PSME4 PSMD14 SKP1 PSMB6 PSME2 PPP2CA PSMD12 CSNK1A1 PSMB1 PSMD6 PSME1 CTNNB1 PSMB4 PSMB9 AXIN1 PSMB2 PPP2R5D PSMC2 PSMC5 PPP2R5C PSMD4 PSMC1 RPS27A UBA52 BTRC CUL1 PPP2R5B	0.038855	DOWN
MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP	ASPM PRC1 CENPA CEP55 CCNB2 NUSAP1 BIRC5 UBE2C RRM2 DIAPH3 PXDN	0.0391121	DOWN
ROSS_AML_WITH_PML_RARA_FUSION	FGF13 S100B STXBP1 SERPING1 RASL12 CDKN1C CFD SMARCD3 MXRA7 MAP1A PTGDS ALCAM GRB10 CERS4 MAP4 ST3GAL6 MRC2 MMP2 MEGF6 STAB1 HGF NISCH TMX4 PXDN ITPR2 ALOX5 CPA3 AQP3 RCN1 AGRN COL2A1 CST7 PRR14 PGBD5 PRODH TNFRSF4 NAALADL1 LRFN4 SLC1A4 AFF2 CTSW ASNS MANF MPO MST1 NDST2 SEC31A TLE1 ARHGAP4 JAG1 HSPA5 PDE3B CHPF2 HYOU1 CALR CCNA1 ANKFY1 LTK P4HB ATG13 FNDC3B GALNS AUTS2 SLC25A38 TMEM87A ARFGEF1 CHN2 IGFBP2 GCNT1 KRT18 CLMN	0.0392751	UP
DOANE_BREAST_CANCER_ESR1_UP	FOXA1 ACADSB KIAA1324 SLC27A2 SLC44A4 NAT1 TTC39A TOX3 AGR2 TFF3 MYB VAV3 TMC5 GPRC5A ABAT TSPAN1 SELENBP1 MYO6 PEX11A PNPLA4 INPP4B GALNT7 KRT18 TJP3 DACH1 IFT74 FBP1 CA12 TFF1 SCNN1A SCUBE2 MLPH SEMA3C CHAD CRIP1 SIDT1 SCCPDH CFB XBP1 MUC1 SYBU SSH3 ANXA9 ACOX2 SCGB2A2 IFT122 HEMK1 SYT17 SLC7A8 SPDEF ELOVL2 UGCG CLSTN2 GREB1 RND1 EPS8L1 AZGP1 DNAJC12 ESR1 PGR BMPR1B PIP C9orf116 KCNK15 CACNA1D ERBB4 MAP3K12 CACNG4 PBX1 MAST4 SLC4A8 DHRS2 SEMA3B TBC1D9 DNALI1 CELSR1 CLGN GFRA1 AR SCGB1D2 PDZK1 TNNT1 STC2 C1orf21 TPSAB1 GAMT SLC16A6 SLC39A6 STK32B AREG BCL2 SERPINA5 EEF1A2 DUSP4 CYBRD1 RET CERS4 GATA3 GDF15 ALCAM MAPT EVL KCNE4 CFD RHOB SYT1	0.0394929	DOWN
HALMOS_CEBPA_TARGETS_DN	CYR61 CTGF ARHGAP29 RBPMS TSC22D3 RHOB MAL FZD7 DUSP10 ROR1 ARL4C TFAP2C INHBB STC2 C1orf61 IFIT1 UMOD PLAU RGS3 KRTAP5-9 GAS2L1 SMAD6 SH3BP2 ID2 NKX2-1 TRIO GADD45A SMAD7 TH HES1 TOB1 TM4SF5 FGF9 ELF3 SCNN1A CHKA BCAR3 DYRK2 MTMR11 GRB7 CLDN4 CEBPA F2RL1 ERBB3	0.0395533	UP
WANG_RESPONSE_TO_PACLITAXEL_VIA_MAPK8_UP	ANXA3 EMP1 FGFBP1 PLOD2 LAMA3 MT1F HIST2H2BE TLE1 FLOT1 CNR2 PLK2 KLC1	0.0396113	DOWN
REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS	RFC5 CDC25C ORC2 CHEK1 HUS1 CDC6 CDC7 ORC5 ORC4 MCM4 ORC1 MCM2 RFC2 RPA3 RFC3 ATR RAD17 ORC6 RAD1 MCM7 DBF4 RAD9A MCM10 RPA1 CDC45 ORC3 CDK2 MCM6 RPA2 MCM5 MCM3 CDC25A RFC4	0.0400151	DOWN
FERRANDO_LYL1_NEIGHBORS	ZBTB16 SELL LMO2 HHEX CD34 LSP1 BCL2 FES CCND2 MYCN GPX1 TNFRSF1A APEX1 SOD2 LGALS9	0.0401381	UP
LEE_LIVER_CANCER_HEPATOBLAST	FOS PTGS2 TNC NR4A1 VIM TIMP1 IL6 CD44 CCND2 PLAUR KRT7 EZR F3 KRT19 LAMA3 MMP1	0.0407586	UP
BIOCARTA_IL3_PATHWAY	FOS CSF2RB STAT5B PTPN6 STAT5A IL3 IL3RA HRAS SHC1 JAK2 RAF1 MAP2K1 GRB2 MAPK3 SOS1	0.0408225	UP
HOOI_ST7_TARGETS_DN	STON1 IGFBP5 ENO2 NNMT CSGALNACT1 RBPMS CXCR4 FN1 ITPR1 ITPKB TRIB2 OBSL1 MCAM COL1A1 C10orf10 SPARC VIM TMEM45A RBP4 FAM131B PPL KCTD15 C5 APOBEC3G PCSK1N TAF15 BAMBI BBX ANGPTL4 PLA2G7 VASH1 TM4SF1 SRGAP3 DHRS2 PDLIM4 KDR FUS ALK PHEX MAGEA3 MMP13 TCN1 PPFIA4 PFKFB4 RPS27 TTN FAM46C RAP2A SLC14A1 MMP10 ID2 MCOLN3 CDH12 EPHB3 SYT17 PAK6 SPRY4 PRKRA TSPAN31 STK17B CADPS2 PDK1 DCUN1D1 IREB2 CRIP1 RNASE4 CCNG2 RIN2 UBR2 CREB3L1 RREB1 LRRFIP2 PGAP1 MLLT3 NDRG1 PDK3 VWA5A TSPAN8 ANK3 DENND1B TBC1D8B MMP1 ZDHHC13 TMEM30B AKR1C3 FOXA1	0.0408265	UP
LIU_TARGETS_OF_VMYB_VS_CMYB_DN	CSGALNACT1 TSC22D3 EAF2 FAM117A ADRB2 COL4A2 IL23A PALLD GATA3 IL6 GPR18 ARHGAP24 CHSY1 CCL20 TPSAB1 NKG7 TFPI2 TM4SF1 EHD1 MAPKAPK2 CSF2 OXTR VCAN CLEC5A IL12B NRIP3 KCNA3 PDGFA CCNA1 SLC38A1 DALRD3 FAM45A CERS6 PTPRJ KLF5	0.0408571	UP
SIG_BCR_SIGNALING_PATHWAY	CR2 ITPR1 AKT3 CD81 PTPRC CD19 INPP5D PIK3CD BTK NFATC1 CD22 MAP4K1 PLCG2 PPP3CC VAV1 BCL2 FLOT2 LYN ITPR2 PPP3CB PIK3CA NR0B2 AKT2 AKT1 PIK3R1 GSK3A FLOT1 CSK PPP1R13B DAG1 SHC1 RAF1 GRB2 PPP3CA SYK BCR BAD PDK1 MAPK3 SOS1 BLNK GSK3B ITPR3 SOS2 MAPK1	0.0409127	UP
BIOCARTA_PROTEASOME_PATHWAY	PSMC6 UBE2A PSMA5 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMB3 PSMA1 PSMA4 RPN1 PSMC3 PSMA2 PSMA7 PSMB7 RPN2 UBA1 PSMB5 PSMD14 PSMB6 PSMD12 PSMB1 PSMD6 PSMB4 PSMB2 PSMC2 UBE3A	0.0414848	DOWN
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN	EGR1 GAS1 ZBTB16 VNN1 GEM ATF3 CLU TFPI TSC22D3 CCL21 RGS2 TGFBR3 CDKN1C SERPINA3 CALD1 PCDH9 LAMB2 BCL6 CCL3 S100A8 IFI16 KYNU C1S IFI44 ENG DAPK1 MAFB PLEKHO2 SNCAIP IFITM2 STOM CXCL1 SAA2 CYBRD1 ROS1 TNFAIP3 THBS3 IFITM3 MME CYP4B1 PNRC1 MMP25 ACTA1 SCPEP1 ATP1A3 TP63 NFKBIA KLRK1 SEMA3B KRT16 AQP3 BIRC3 EIF4B TCF3 SPRR3 GBP2 BTG1 KLF6 INSIG1 DST SND1 TRIM29 LPAR6 IL1RN RPL37 CXCL3 EEF2 IL1R1 PSAP DSC3 RPLP1 STAT3 MAP3K5 BNIP3L IFNGR1 CAPZB UBE2H NFE2L1 PSME1 MKNK2 SDCBP CREG1 TACSTD2 KRT14 HIST2H2BE USP15 DLG5 ACSL1 HLA-E PLXNB1 SRSF8 GADD45G CITED2 POLR3E PTEN KRT13 CFB CCNG1 ZCCHC6 GLUD1 KLRC3 PIK3C2B SAT1 TKT FOSL2 SEMA3C SOD2 TMEM59 LETM1 NFE2L2 PC CD9 MXI1 SPRR1B CTSD NCK1 ALG6 MAOA CCNB2 EFNA1 MVP SCD ANK3 NFIL3 FXYD3 KRT19 CDH1 DSP F11R HIST1H2AC VAV3 FGFBP1 CA2 PDZK1IP1 RARRES1 ADH1C DSC2	0.0415803	UP
HARRIS_HYPOXIA	FOS PTGS2 TAGLN CCL2 IGF2 SPP1 BHLHE40 TGM2 TGFB1 BNIP3 JUN CP VIM TGFB3 TEK PDGFB PRPS1 IL6 SLC2A3 STC1 COL5A1 L1CAM IGFBP3 EPO HGF LRP8 FGF3 HDAC9 DDIT3 PGF ANGPT2 FLT1 CD99 PLAUR HK1 MMP13 PFKP HIF1A CA9 TF APEX1 XRCC5 BNIP3L XRCC6 MIF CDKN1B EPAS1 FTL P4HA1 IGFBP1 GAPDH ENO1 NFKB1 VEGFA BIK LDHA PFKL ADM PGK1 TH ALDOA SAT1 SLC2A1 CCNG2 CDKN1A EDN1 TFRC EDN2 F3 IGFBP2 CA12 TXN HMOX1 ENPEP HK2 TFF3 TGFA	0.0419283	UP
HU_ANGIOGENESIS_UP	FOS STXBP1 LCAT NRGN COL7A1 PIK3R1 PRODH STUB1 NMD3 HECW1 RND3 CLTA SIPA1L1 ID1 FAH ITGB4 SEMA3C NAPG	0.0419383	UP
ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP	MGP GUCY1A3 SULF1 RBPMS DLC1 NAV3 ITIH5 CALD1 PRKD1 KIF5C AKT3 DFNA5 PDE1A PRNP COLEC12 LIMCH1 ARHGAP10 PDZD2 LMO2 COL1A2 PAM MAGEH1 RNASE6 DYNC2H1 OSMR PRKAR2B ARHGDIB AIM2 PALLD CYTIP INSL5 CREB5 SSBP2 SELP IL6 SLC1A3 IPCEF1 STEAP4 CXCL1 MARK1 NTF3 HOMER1 TOX PIK3CG TMSB15A CHST2 PRKCQ IKZF1 OSBPL10 AREG CLEC7A SMAD9 KDM4D COL3A1 SCN11A MMP8 GLRB SATB1 PRKACG FAM189A2 KLRK1 IFNA6 CACNB2 OPHN1 BICD1 RNASE1 BTC H2AFY2 FUT8 CSRNP3 PDE6H CTNNA3 MARCO GMPR TOMM7 MAST4 HTR7 GPR1 PBX1 FZD8 TCF3 MGA HAUS5 PRPS1L1 AGTR2 CHRM3 KCNK2 CCR9 F11 TYR C9 TLR2 SV2C FZD1 KL OR2H1 MPP1 POU6F2 MAGEB2 CYP2E1 RHAG TLR8 IGSF1 NFIB PRMT2 OCA2 FRAS1 COL19A1 GDF3 BMPR1B MAGEA9 IL1RL1 PNLIP EDDM3A TTN MMP27 DSC3 CSAG3 IFNA13 MAGEB3 HSFX1 SERPINB2 TMPRSS11E TBC1D30 YTHDC1 TMOD2 CPB1 CRISP3 QSOX1 MAGEA2 TANC2 MAGEB4 SPP2 MCOLN3 DEFB126 CDH12 MAGEB1 IFNA1 NCALD SERPINB13 MAGED1 GABARAPL2 ZNF471 KLRC4 UBE2G2 NOP10 PES1 DNASE2B EDDM3B PLA2G2A CRB1 ST18 FAM192A HSBP1 HSPD1 LPAR3 PTEN MBOAT2 OAT GPBP1L1 SLC12A6 ANGEL1 GSPT2 GRM8 PLSCR2 SEMA3C PELI2 TMEM144 CRISP2 SCIN PRIM2 C1GALT1C1 ENDOD1 CSTF2 MLLT3 PLBD1 SEMA6D SRI C3orf52 HSPB3 TNIK SLC35F2 B3GALT5 AGR2 GCG GUCY2C PTPRR CLCA1 ESRP1	0.0422952	UP
HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP	RTN1 HBA1 STMN2 FLNC OLFM1 PNMA2 CD81 FSCN1 SST PCSK1N ATP8B2 NPTX2 EEF1A2 ELAVL3 MXRA5 DCX BRSK2 TNFRSF8 TAGLN2 MT1G MT1F ZNF91 ITM2C FAM171A1 GPX2 SCD HOXB9	0.0422981	UP
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP	PTGS2 GEM CES1 ITGA7 MEIS1 CFD FN1 GPX7 ADAM19 HBB LBH LAMP3 EREG HOPX CD1C HOXB2 OAS2 PTGFR LY6E PRKAR2B IFI44L TPSB2 IFI44 LUM PALLD RAB33A CCR6 GPR18 MAP4K1 ZDHHC17 CFP PPP1R16B SAMHD1 LSP1 CCR2 CDC42EP3 IDO1 ABCB4 IFI6 MX2 FGL2 ATP10A DUSP4 TOX CHST2 IKZF1 TPSAB1 AFF3 TFR2 IL6ST FCER2 KIT MEF2D LTBP1 IRF4 ITGB7 IFIT1 HOMER2 CPA3 LILRA1 HBD AHR SMYD3 MX1 CFI ISG15 NRG1 ATP11A WT1 PRKAR1A CD1D ABCD2 CD1E CD1A HOXA3 SIGLEC6 HOXB3 SLAMF7 CD38 IFITM1 SLC18A2 XAF1 LIF USP18 RAB27B TGM5 OAS3 ADRB1 STAT1 NCALD SPINK2 IFIT3 FCAR SLC12A8 CCNA1 DENND5B LGALS2 LPAR3 BCL2L11 SLC38A1 THBS1 NDRG2 PTPRK NET1 XYLT1 FHL2 AUTS2 APH1A IFIT2 PDLIM1 SOX4 REN FLNB HOXA7 HOXA5 TNFSF10 FKBP1B PRSS3 OPN3 IFI27 HPGD CDH17 SMPDL3A ELOVL6 GNAI1 HOXA9 OASL DEFB1 RSAD2	0.0423021	UP
KONDO_EZH2_TARGETS	CTGF MAB21L2 FABP4 HLF IGFBP5 TFPI CAP2 NNMT BCL2A1 ZEB1 WWTR1 SPOCK1 FHL1 KLF2 SAMD4A KCNMA1 MS4A1 NRP1 ELMO1 ARHGEF3 MYLK CPE COL1A1 CP RBMS3 SPARC FLI1 TYRP1 TMEM45A CSGALNACT2 LY9 C1S RBP4 DOCK4 LMCD1 MAP4K4 SSPN NCF4 UST ADCY7 ST3GAL6 APBB2 ITGBL1 AOX1 IFI6 TNFAIP6 TMSB15A ST3GAL1 CCL20 GJA1 SERPINE1 MYO16 HOXC8 CNIH3 IGFBP3 NOL3 COL3A1 MEF2D NAV2 RAB3B SGK1 SCN2A VAMP4 MAP3K8 TACR1 PRKAR1B UTS2 EDIL3 ANO1 PRB3 IL1B YPEL5 GNA14 EPHA5 KLF9 DPF3 SIGLEC5 SLC4A8 IRX5 MSX2 GLP1R AKAP13 DLX2 GRK4 ZNF76 RRAGD PRR16 SUSD4 MTHFD2L SLC25A16 TPM3 STMN3 MATN3 SERPINB3 LPAR6 C9orf116 TNRC6B USP34 ADAM12 TSC1 MAGEC2 NDST2 SNTB2 AP3B2 ANXA10 RBMX FAM175B CYP19A1 ABI3BP CTSB VPS13C OR12D2 COL8A1 ELOVL2 IQCA1 ID2 ATP8B1 ZFX CXCL5 ZNF175 GABARAPL2 TNP2 MCPH1 AHCTF1 IFIT3 MYEF2 SPRY4 GAL3ST1 CD59 LMAN1 GULP1 NEBL HAS2 COMMD10 MAP4K3 APP ST6GALNAC4 GALNS SCARB1 SORL1 CD164 NT5E RNASE4 EGFR ATXN3 WDR61 IFIT2 PRIM2 MGLL IL13RA1 NIP7 ARHGAP5 SLC2A10 C18orf25 C1D ABCA5 CFDP1 HRASLS2 TNFRSF21 PYROXD1 EPB41L3 ITGA6 MAGT1 KLF3 SLC12A2 TRIM2 TSPAN8 ATP9A NPAS2 HPGD NEK3 MMP1 AVL9 IL6R EMP1 PCK1 ACAD8 PCLO HIST1H4H FAR2 MYO1D HSD17B2	0.0423027	UP
REACTOME_CRMPS_IN_SEMA3A_SIGNALING	DPYSL3 NRP1 SEMA3A DPYSL2 FYN CRMP1 FES CDK5R1 PLXNA3 PLXNA1 DPYSL4 CDK5 PLXNA2	0.0427204	UP
ZHAN_MULTIPLE_MYELOMA_DN	CXCL12 DPYSL2 VCAM1 COL1A2 ITGB2 RNASE6 HHEX PRKAR2B MRC1 CD27 CTSH CD72 APOC1 CEBPD A2M LST1 TCF7 AIF1 PLA2G7 S100A9 APOE PYGL WNT10B ITGA2B GLDC IGF2BP3 LIPA S100A12 CD99 ELANE PF4V1 MSX1 LYZ GP5 ALDH1A1 SYK PF4 LCN2 CD24 SMPDL3A HNMT	0.0427605	UP
BIOCARTA_EPHA4_PATHWAY	ITGA1 FYN SELP EPHA4 L1CAM ACTA1 LYN EPHB1 ITGB1 RAP1B	0.0431783	UP
PID_AVB3_INTEGRIN_PATHWAY	COL14A1 FN1 SPP1 IRS1 COL5A2 COL15A1 COL6A3 COL4A1 COL1A1 COL6A2 COL1A2 COL16A1 CSF1R FGF2 IGF1 TLN1 COL6A1 COL8A2 MFGE8 COL5A1 TGFBR2 ILK COL7A1 COL9A3 COL3A1 VCL EDIL3 PIK3CA COL13A1 COL9A2 COL9A1 CSF1 PTPN11 COL11A2 KDR COL2A1 COL10A1 ROCK1 AKT1 PIK3R1 COL4A4 COL11A1 PI4KB PTK2B ITGB3 HSP90AA1 CBL PTK2 COL4A5 COL8A1 ANGPTL3 VTN CDKN1B PI4KA RHOA ITGAV COL4A3 IGF1R PXN PIK3C2A SRC VEGFA COL4A6 RPS6KB1 RAC1 CASP8 MAPK3 MAPK1 F11R VAV3 SDC1 COL17A1	0.0433852	UP
ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN	PTGER3 BACH2 WIPF1 ST8SIA1 CPE PTPRC TGFBR2 WNK1 BCL2 LEF1 SATB1 CDK17 UTRN STK10 JAK1 BCL11B LRCH1 LPAR6 FAM69A GFI1 DPH5 PTK2B RCBTB2 ABTB2 NIPBL PELI1 RAPGEF6 NRIP1 TRIM34 SYNE2	0.0434342	UP
BIOCARTA_IL2_PATHWAY	FOS JUN STAT5B LCK IL2RA STAT5A IL2RB IL2RG JAK1 ELK1 JAK3 HRAS MAPK8 SHC1 RAF1 MAP2K1 GRB2 IL2 SYK MAPK3 SOS1 CSNK2A1	0.0435642	UP
GUO_HEX_TARGETS_UP	RTN1 AKAP12 WWTR1 FBLN2 ISLR KLF7 NRP1 FZD4 PTPN13 GNG3 ZFHX3 WWC2 NNAT LIFR NDN SOX11 TBL1X PCGF2 EPHA4 SATB1 FGD1 GRIK5 POU2F1 TES KLF9 SLC6A6 PGF MAGEL2 PCM1 REST RRAGD MMP14 CD99 EFNA2 ERF AKAP8 SMARCC1 UBE3A RBM39 PTPN1 LUC7L2 PURA WDR26 GLG1 PTCH1 ARSA CD2BP2 SRSF7 URM1 BMP4 AKTIP CALM3 CMTM6 MTF2 AGFG1 CD59 ABCD4 IGF1R ATXN2 RAB6A IQGAP1 TBX3 VEGFA IMPAD1 ENY2 EFNA3 PTEN SNX5 NAA15 EXT1 ATP6V1A KDM6A SP1 DIAPH2 MARK2 ZNF322 STIL ELOVL6	0.0439522	UP
REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION	CCNB1 ORC2 PPP2R1B DHFR CDC6 FBXO5 ORC5 PRIM2 ORC4 CDT1 ORC1 CDK1 TFDP1 PPP2CB TYMS PCNA CCNA1 PPP2R1A POLA1 ORC6 RRM2 PPP2CA RB1 PRIM1 PPP2R3B CDC45 ORC3 CCNE1 TK2 E2F1 CDC25A POLA2	0.0441766	DOWN
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN	FOSB RGS1 NR4A2 TSC22D3 RGS2 CD69 NR4A3 PPP1R15A DUSP10 WIPF1 PRNP JUN TUBB2A ZFP36 ZNF331 PER1 CSGALNACT2 LY9 CREM DUSP2 GATA3 SLC2A3 TSPYL2 PDE4D IDS DUSP4 TNFAIP3 AREG PHF1 CHD2 KLF10 CD6 REL TMX4 MAP3K8 TSC22D2 JUND CBX4 YPEL5 SRSF5 MOAP1 PCIF1 ZBTB24 MCL1 CCNL1 KDM6B SIK3 BTG1 ZFAND5 KLF6 H3F3B RNF139 GADD45B MEX3C PTGER4 CCDC59 EIF1 JMJD1C SON TRA2B PMAIP1 TIPARP SETD2 IRS2 ID2 KDM3A DDX3X CLK1 ING3 RSRC2 EIF4G3 IKZF5 PTP4A2 HIPK1 GADD45A HAUS3 SMURF2 HECA ZFC3H1 MYNN PELI1 STK17B RNF11 RAPGEF6 IFRD1 BCL10 AMD1 PIGA EIF5 MYLIP FOSL2 OPA1 PTP4A1 IER5 CHD1 KLF4 G3BP2 B3GNT2 EIF4E TOB1 RNF103 NDUFA10 MXD1 SLC30A1 NAMPT ZBTB10 MGAT4A ETNK1	0.0443614	UP
BIOCARTA_ERYTH_PATHWAY	TGFB1 CCL3 IGF1 TGFB3 IL6 EPO FLT3 CSF3 IL3 TGFB2 IL11 CSF2 IL9 KITLG IL1A	0.0443759	UP
JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP	FABP4 CLU NR4A1 IGF2 SPOCK1 TIMP1 PRKCB GDI1 CETN2 CD82 IFI30 FURIN PSAP SERPINB2 NME1 POLR2L GSTP1 S100P RHOA PCMT1 SEC61B MT2A PRDX1 SAT1 COX6A1 RAB11A UQCRQ HADHB ATP5G3 GPRC5A	0.0444023	UP
ABBUD_LIF_SIGNALING_2_UP	ANGPT1 NRP1 DCN FGFR1 JUNB PPP2R2B PTPRO DIO2 COL11A1 PFKP EZR ATP1B1 GPX2	0.0444532	UP
JIANG_AGING_CEREBRAL_CORTEX_UP	TIMP3 EGR2 RDX EPHA7 CPE COL6A2 VIM GRIA2 DCK RPL5 RASGRF1 SLC25A4 CDC5L GADD45B RPS24 ACTB EIF1 TRA2B TPT1 PABPC1 PPIA PRDX1 PAFAH1B1 UBE2E1 FKBP3 FAH CCNG1 C1QBP BCAP29 MARCKS SOS2 PREP CASP6	0.0445057	UP
NIELSEN_LIPOSARCOMA_DN	TNC CSRP2 TRPS1 APLP1 CYFIP2 NRP2 INHBA ETV4 FZD1 CHML MYEF2 PPP1R13L ARHGEF5	0.0446363	UP
WINNEPENNINCKX_MELANOMA_METASTASIS_DN	PCP4 P2RY14 CLEC3B STMN2 PTGDS DPYSL2 CD1C HLA-DQB1 LTB F10 LSP1 CLEC10A CRY2 PIK3IP1 KIAA0930 TXNIP CD1A CA5B CLIC3 EMX2 XCL1 CST3 TOM1L2 CTNNBIP1 CST5 RNF125 CXCL14 LGALS2 GPRIN2 DHRS1 ALDH3A2 SPINT2 CEBPA HOXA9	0.0449774	UP
BIOCARTA_FCER1_PATHWAY	FOS JUN BTK NFATC1 PRKCB NFATC4 PPP3CC PIK3CG VAV1 FCER1G PLCG1 LYN PPP3CB PIK3CA MAP2K7 PLA2G4A NFATC3 PIK3R1 MAP3K1 ELK1 PAK2 HRAS MAPK8 FCER1A SHC1 CALM1 RAF1 MAP2K1 GRB2 CALM3 CALM2 PPP3CA SYK MAPK3 MAP2K4 SOS1 MAPK1	0.0450469	UP
REACTOME_GLYCOSAMINOGLYCAN_METABOLISM	OGN LYVE1 CSGALNACT1 SDC2 PRELP DCN OMD CHST15 SDC3 CSPG4 CHST11 CSGALNACT2 DSE LUM BGN HS3ST3A1 UST CHST3 ST3GAL6 HS3ST2 CD44 GPC1 HSPG2 CHST12 IDS HYAL2 CHST2 CHSY1 ST3GAL1 FMOD ST3GAL2 GPC3 CHST7 STAB2 ACAN HAS1 CHST6 B4GALT6 HPSE2 B4GALT2 GPC5 CHPF IDUA B3GAT3 NDST4 AGRN HYAL1 B3GAT1 ARSB HS3ST1 SGSH GPC4 BCAN ABCC5 VCAN B4GALT7 HS6ST1 CHST1 B3GNT4 NAGLU NDST3 NDST2 HS2ST1 KERA NDST1 NCAN HS3ST3B1 CHPF2 HEXA GNS B4GALT1 HAS2 SDC4 EXT2 EXT1 B4GALT3 B4GALT4 GUSB SLC9A1 CHST5 HEXB B3GNT2 B3GNT3 B4GALT5 GLB1 HMMR SDC1 HPSE GLCE	0.0451417	UP
BILBAN_B_CLL_LPL_UP	AKAP12 DMD PEG10 SGCE ARMCX2 FRY BACH2 KANK2 LPL DFNA5 CCR7 ELMO1 PNMA2 DIP2C OAS2 GPR18 SIT1 KIAA0040 BCL7A FCER2 ABCA6 PIM1 IRF4 SLC23A2 CREB3L2 KLK2 MYBL2 TBC1D1 DCLK2 ATOX1 TLR7 FAM69A AZIN1 ST6GAL1 TRRAP BNIP3L HEATR1 TOP1 FBXW11 SIAH1 RRBP1 ST6GALNAC4 MFAP1 BCL10 SEPT10 ZFP64 TMEM140 FLNB CPT1A WSB2 DNMBP NSF IGSF3 ATP6V0A2 SERINC5 SLC39A14 AGPAT5 CYP51A1 CEACAM1 OAS1	0.0459366	UP
MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN	BEX1 FHOD3 ID4 NBEA NOTCH3 PRKD1 DIXDC1 PLTP RPRM MCAM HEY2 RAI2 SCN3B STMN4 CERS4 SLC27A3 DAPK1 JAG2 ARHGAP24 COL9A3 FGF18 SATB1 CPZ LDHB SEMA3D PRKG1 HOXC13 ABCA1 TEX15 MAN2B1 DGKA PMAIP1 ID2 RB1 ELAVL2 DFFB PLXDC2 GARNL3 MMP15 EPHB2 CD55 MTUS1 GCA FAS BBS7 ATP8A1 RAB40B IGFBP2 ABAT MPZL2 PERP CKMT1B PITX2	0.0462345	UP
BOYLAN_MULTIPLE_MYELOMA_PCA1_UP	GPM6A ZBTB16 NBEA ARMCX2 ARHGAP6 LTF C3 MMP9 PLA2G16 CPE S100A8 BASP1 CP CACNA1H GIMAP4 CTSG IFI16 RASGRP3 ALCAM ITK LTB FSCN1 ITGAL ZBTB20 FADS3 CD3D CCR2 B3GALNT1 RECK FGL2 HDC IFITM3 FPR1 TGFBI TFEC NKG7 S100A9 CAMP FYB IL18R1 PRTN3 ZBP1 PGLYRP1 PRG2 IL2RB ATAT1 LTB4R ELL2 CRYBA4 CXCR6 STAT4 ELANE AMY1A HP CTSW IGSF6 ISG20 DDX3Y CHST1 MPO ARMCX3 CCL5 FAM46C ABI3BP AFP TNFRSF17 PRLR LPAR4 CACNA1S OSBPL3 MAGED1 TMEM176A APP F2R SMR3A PAWR PLIN3 PLSCR1 CD9 LCN2 SPON1 CPEB3 EPCAM SLC25A24 XDH VAV3 WIPI1 F2RL1 CD177 HOOK1 GRAMD1C	0.0464774	UP
NELSON_RESPONSE_TO_ANDROGEN_DN	BCHE PEG3 FN1 PRKD1 SERPINI1 SLC29A1 MYC BARD1 PIK3R3 MMP16 CTBP1 ST7 DPH1 TULP4 SDC4 SCNN1A CDK8 DDC	0.0468714	UP
HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP	FEZ1 TSC22D3 CFH FBLN1 FLNA LDB2 ITPR1 KANK2 CCL19 DENND5A LBH COLEC12 JAM2 VCAM1 SERPINF1 RGS5 NUAK1 CCDC85B GMFG LY86 ITM2A CD52 LMCD1 HLA-DQA1 MAP4K4 TCF4 CUTC CTSH CLDN5 IL7R ERG ITGB1BP1 ARL3 DAB2 LST1 SLA TOX ARMCX6 TBC1D16 GSN NME7 FXR1 BARD1 IGFBP3 FBXO11 MPRIP CIRBP NTRK2 C6orf48 SATB1 CCND2 PTPRO LRRC15 CREB3L2 TM4SF1 JUND CPA3 SUPT16H ZNF292 ARPP19 RBM15 C19orf60 TNPO1 RECQL SNCA NUDT1 LIPT1 SNRNP70 SRSF3 ZNF22 NUCKS1 SPTAN1 TXNIP RPL23 ARL6IP4 NME3 MKL2 PWP1 SAFB CRIM1 ERH GEMIN6 NFIB SRRM1 SSR2 SUZ12 DPH5 RBM25 SART3 PFN1 SF3B1 HNRNPA1 RCBTB2 HNRNPU RPS21 EIF1 WBSCR22 ELAVL1 GNB1 TNFRSF1A CKLF PPIB APEX1 CTBP1 NSL1 FOXO3 SNRPE CALM1 CAPZB RBBP4 SAFB2 PPIH THYN1 CLEC4A UBE2Z LAMP1 CERS2 SMS CNN3 EIF3A CCNB1IP1 YTHDF1 SHOC2 P4HA1 SRSF9 ITGB3BP CRBN IFT20 SNX6 YWHAZ C6orf62 RPN1 TRAK2 RTN3 SREK1 PSMB3 ARF5 DPP8 MED13 IP6K2 UPF2 ATG12 ZNHIT3 SP3 EHD4 RAPGEF6 TMEM14A GLUD1 GPI STOML2 MFAP3 ANXA11 CAPZA2 PDIA4 MGAT2 PDCD4 ARPC1A PRKCI ORC5 MARCKS SOX4 GCA NDUFA8 BACE2 PDGFD CASK C1orf115 CASP1 EAPP TRIM2 SEMA5A ETHE1 HPGDS	0.0470973	UP
PID_CD8_TCR_PATHWAY	FYN PTPRC RASGRP1 LCK MAP3K14 PRKCB CD86 RASGRP2 LCP2 CD3D CD3E VAV1 CD247 PRKCQ PTPN6 ZAP70 CD28 LAT PLCG1 CD8A PRKCA MAP3K8 GRAP2 MALT1 CD8B IKBKB AKT1 TRPV6 PRF1 IKBKG STIM1 CSK PRKCE RAP1A CD80 HRAS CBL SHC1 PDPK1 GRB2 B2M CD3G TRAF6 HLA-A BCL10 SOS1 KRAS CHUK NRAS	0.0471324	UP
RODWELL_AGING_KIDNEY_NO_BLOOD_DN	CTH FMO5 GSTM4 FA2H PCLO TOX3 C5orf30 CEP70 BCKDHB TMEM38B PHYH DSG2 GMNN RALGPS1 DHTKD1 TMPRSS2 TSPAN7 NDUFS1 NAA35 DLAT ERLIN2 ECI2 AK2 CPEB3 CLDN8 ALDH6A1 FBXO3 PPP2R1B MUT TPD52 ATP5G3 RHOBTB3 TCTN3 IMPACT SP2 UCHL5 UAP1 ABCA5 ISCA1 FAM171A1 CYCS NNT CSNK2A1 HADHB ENOSF1 SCML1 LRPPRC WDR61 ISOC1 EGF CYB5A AMT AUTS2 COX7B ATP5A1 NEDD4L PPFIA1 PRDX3 HSPA9 COX8A ZNF711 COX6C APLP2 KNG1 SRP9 OAT AHCYL1 RBM14 COX7C NEBL SLK KIAA0141 GOT2 ZBTB43 IGF1R USP9X RTN4 MTO1 ATXN7L3B CCNB1IP1 FBXO21 PEBP1 ADH5 THRB GAD1 PAIP1 SLC25A36 SHANK2 PCBP2 ADCY1 TMEM80 ESRRG GNAS RPL10 C3orf14 BCAN AASS LRRC2 ZFAND5 GSTA4 KLHL24 SOHLH2 KLF9 C2orf68 LDHB DBT TBC1D9 OXCT1 SRR PTPRO CLASP2 NUDT7 FOLH1B KLHL3 GABARAPL1 BMP7 MTR PRKAA2 WNK1 PALM GHR SLC16A7 CRABP1 SULT1C2 MPPED2 GPRASP1 LPL THSD7A ITPR1 PTGER3 PEG3	0.047155	DOWN
NIELSEN_SCHWANNOMA_UP	PLP1 S100B NRXN3 NLGN4X NRXN1 PLEKHB1 RASSF4 SERPINA5 L1CAM SEMA3B APOC2 ADORA3 TREM2 NKX2-1 GFAP ST14 SLC26A2	0.0473589	UP
HASLINGER_B_CLL_WITH_6Q21_DELETION	CEACAM1 HIST1H2AC HIST1H2BD HIST1H2AG HIST1H2BG HIST1H2BI HIST1H2BM CAPG UFL1 MAP3K7 RAP1GDS1 SNX3 SEC63 EXOSC10 HIST1H2AL NUP98 ARHGAP1 MDN1 HIST1H2AK	0.0475682	DOWN
KEGG_AUTOIMMUNE_THYROID_DISEASE	HLA-DOB HLA-DQB1 HLA-DQA1 HLA-DRA HLA-DPA1 HLA-DMA HLA-DRB5 CD86 HLA-DRB1 HLA-DRB4 HLA-DMB HLA-DPB1 CD40 IFNA10 CD28 IFNA4 IFNA16 CD40LG IFNA6 CTLA4 IFNA7 IFNA21 CGA TPO IFNA8 TG IL10 TSHR FASLG PRF1 HLA-DOA IFNA14 TSHB IFNA2 IL5 IFNA13 CD80 GZMB IFNA17 IFNA1 IL2 IL4 HLA-E HLA-C HLA-G HLA-B HLA-A IFNA5 HLA-F FAS	0.047573	UP
HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP	GEM HLF TIMP3 MITF TYRP1 RASGRP1 CD53 GHR MAF PRAME SGK1 MAGEA12 GAGE12I HIST2H2BE FGG NEUROD1 PMEL NT5E TNFRSF11B CDKN1A WDR44 POSTN	0.0476222	UP
WANG_RECURRENT_LIVER_CANCER_UP	USH1C KCNK1 SH3GLB2 ZBTB38 MPHOSPH9 RACGAP1 SMURF2 SSR3 DNAJC10 SYNGR2 CUL4B RBM41 PARD3 R3HDM1 ZNF652 RPL10A PTPN11 CETN2	0.0477243	DOWN
KEGG_OTHER_GLYCAN_DEGRADATION	NEU1 GLB1 AGA GBA FUCA1 HEXB MAN2B2 HEXA ENGASE MANBA MAN2C1 NEU3 MAN2B1 NEU2	0.0480853	DOWN
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP	UCHL1 AMIGO2 TUBB6 CH25H RBPMS BCL2A1 ARMCX2 KLF2 LPL GPNMB PLTP DENND5A SCG5 JAM3 CD79B RHOQ LAMC1 JUN TIAM1 SLC15A3 CD200 COL1A2 OAS2 SIRPA IFI16 RASGRP1 CREM IFI44 GDF15 CD180 DKK2 ARAP3 SSBP2 ERG MAGED2 BAALC IRAK3 CXorf21 SLC1A3 JAG2 VSIG4 DUSP6 HERC5 VAT1 SOCS3 GPR20 CD163 PALM IFI6 EEF1A2 LRP3 HOMER3 C3AR1 PNRC1 PTP4A3 MAF ENPP2 TNNT1 LAIR1 PXDN PHLDA1 HSPB1 TFPI2 TM4SF1 ALDH1A2 CRHBP PLK2 SLAMF8 LILRA1 LILRB1 TRIB3 CD1D FABP3 NUPR1 ECM1 NTS CYP1A1 SPTAN1 GBP2 BTG1 RRAGD KLF6 DNASE2 ATXN1 OLR1 TLR2 ELANE SLCO4A1 TLR7 VCAN IL1RN CLEC5A ADAMTSL4 SLC7A11 LILRA2 TREM1 MYOF NRCAM CCL7 STAT1 CXCL5 TMEM110 IL1RAP ACSL1 FCAR PDGFA DNAJB2 GIPC1 AP1S1 TMEM176A PLAT APP ID1 SLC2A5 FNDC3B MAPK3 EXT1 NRIP1 PIK3C2B TMEM176B TCF7L2 ANXA2 ARL4A MAN1A1 ADCY9 SOX4 PPARD TNFRSF21 DDR1 SPATS2L ZNF217 NDRG1 FUT4 ACVR1B SERPINA1 QPRT MALL CPD PAPSS2 UPP1 TPK1 IL17RB P2RX4 EMP1 DHRS9 HOXA9 CPM NQO1 NETO2 ETNK1	0.04829	UP
NAKAYAMA_FGF2_TARGETS	GREM1 OLFML3 ACTA2 CXCL12 COL5A2 COL4A1 COL1A1 IGF1 PDGFRB BRPF1 SNRPD2 COL2A1 ZFR2 COL8A1 MYL6 CXCL14 VPS35 IFNAR1 DPM3 MSMO1 GPT ARL15 TTF2 ACE2	0.0484448	UP
BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN	THBS2 TIMP3 TNC CFD DKK3 LBH CPEB1 NTM TPD52L1 MAFB JAG2 EPHA2 COL5A1 MYC SERPINE1 BIN1 SMAD9 KLF10 TNFRSF12A KIT CD70 WNT11 SEMA3B PDLIM4 IL11 KCNG1 AJAP1 GADD45B BMP4 SH3BP4 BMP1 ITGA3 DGKD BCL2L1 VEGFA ID1 ITGB4 EPHB2 CARD10 FLNB SOX9 GCNT1 STEAP3 VDR F2RL1	0.0486947	UP
DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP	FOS NNMT CXCL12 PCDH7 IGFBP6 RASSF2 TGM2 CTSH NMB PTPRN KCNG1 ADORA1 MDK E2F5 ISG20 RIMS2 GNG4 LHX2 HOXB5 PTX3 EFNB2 IGSF3 EPB41L3 IGFBP2 KRT18 MEST ANPEP	0.0487141	UP
ISSAEVA_MLL2_TARGETS	FLRT2 PRKCDBP SCHIP1 LOXL1 AXL CRIP2 FHL1 PCDH7 IGFBP6 FSTL1 CADM1 MEOX1 CSPG4 NPR3 ALCAM PPP2R2B C5AR1 PPL A2M DENND3 COL5A1 ENO3 GSN DUSP9 TNNT2 COL9A3 L1CAM SLCO3A1 HDAC9 SEMA3B AHNAK LOXL2 PLAU SNCA FABP3 KRT17 TRIM29 TNNC1 SMAD6 DKK1 INSL4 VTN TAGLN2 LMO1 CRIP1 NT5E CD9 ELF3 NEDD9 HSPB3 TJP2 BMP5 LAMB3 SLC16A5 OAS1 HPSE IL18	0.0487352	UP
PID_IL6_7_PATHWAY	FOS MITF JUN JUNB PIAS3 TIMP1 IL6 CEBPD CEBPB A2M SOCS3 TNFSF11 LMO4 MYC VAV1 LBP IL6ST PIK3CA FOXO1 PTPN11 MCL1 AKT1 JAK1 PIK3R1 HCK MAPK11 PIAS1 TYK2 CRP STAT3 JAK2 STAT1 GRB2 HSP90B1 FGG BCL2L1 RAC1 IRF1 GAB1 PTPRE MAP2K4 MAPK14 SOS1 GAB2 PRKCD MAP2K6 IL6R	0.0488353	UP
KRASNOSELSKAYA_ILF3_TARGETS_DN	GAL DMD IGFBP5 MN1 THBS4 AXL OLFM1 ROR2 GATM TEK SLC1A3 CELF2 CDH11 NDN NPTX2 IRX5 MSX2 HCFC1 COL2A1 KIFC1 NMT1 SRSF6 ASNS CREBBP CYP19A1 TROAP MAPK7 LIG1 PSPH POLD2 RAD52 TAF4 ARHGAP11A SREBF2 NT5E ESPL1 LMNB1 PC CDC6 HMGCS1 PCK2 IL6R XK UGT8	0.0488704	UP
REACTOME_COMPLEMENT_CASCADE	C7 CFH CFD C3 C1QA C1S PROS1 C5 C1QB C4A CR1 C6 C2 CFI MASP1 C8B MASP2 C9 MBL2 CRP C8A C8G CFB CD55 C4BPB CD46 C4BPA	0.0488925	UP
BIOCARTA_ARENRF2_PATHWAY	FOS JUN MAFF PRKCB PRKCA FXYD2 MAFG MAPK8 CREB1 MAFK KEAP1 MAPK14 MAPK1	0.0488977	UP
PID_FRA_PATHWAY	MGP CCL2 THBD DCN MMP9 JUN JUNB COL1A2 BGLAP NFATC1 IL6 CCND1 MMP2 GJA1 JUND PLAU FOSL1 NOS3 NFATC3 ATF4 USF2 CDKN2A PLAUR IVL DMTF1 LIF EP300 TXLNG ITGB4 FOSL2 SP1 HMOX1 LAMA3 MMP1 CCNA2	0.0489319	UP
LEE_LIVER_CANCER_SURVIVAL_DN	ECT2 ANXA3 KLF5 CD2AP TTK DSG2 RALA CCNA2 CCNB1 DLGAP5 C1orf106 KRT19 LXN ANXA4 DYRK2 ZWILCH RAB32 PNP ATP2B1 HN1 CCDC6 CKS2 MRPL42 NSF SPC25 TPRKB FABP5 CENPF SMC2 DEPDC1 PHLDA2 MARCKS DCTPP1 RPE TSPAN3 ITPR3 NFE2L3 DYNLT1 KIAA0101 TOPBP1 ATP5C1 CDCA8 MCM2 CD164 UBE2D1 CLIC1 S100A6 PELI1 PLP2 ACTL6A BZW2 EIF4A3 YWHAH YWHAB CCT5 PFDN4 OPLAH SLC44A1 NLRP2 NCBP2 PCNA KRT10 DYNLL1 YWHAQ IGF1R HIST1H4C DEK HMGN1 AGFG1 CALM2 RND3 TMSB4X HIST2H4A METTL5 HIST1H4A BUB3 HDAC2 RBX1 MYH2 ACTR3 MCM7 CCT6A RPSA SLBP HMGB2 ATAD2 SNRPG GTPBP4 USP1 KNTC1 RPS18 RWDD1 PTMA KHDRBS1 MFSD10 RPS3A DBNDD2 RPL36A FBL LAMB1 HIF1A MAPRE1 HNRNPA1 SNRPB2 RPS6 RPS9 RPL31 HDDC2 PDCD5 KIF5B CTBP2 RPS3 SUZ12 MCM6 RPS7 RPL17 CBX3 RPL27 RPL9 PRMT2 RAN SUMO2 RPL12 RPS5 RPL38 OLIG2 RPL35 BCAT1 SET RBM17 EEF1E1 TUBA1B CDK4 NPM1 HNRNPC NTS NOP56 PBX1 UBA2 SLC34A1 AGRN TES ODC1 PRMT1 SEPT7 VCL MTHFD2 SERPINH1 MMD MSH6 ITGB1BP1 NAP1L1 IER3 ZNF532 RGS2	0.0490207	DOWN
PLASARI_NFIC_TARGETS_BASAL_DN	EPHA3 SLIT2 IGFBP6 MFAP4 MEOX1 FLI1 RBP1 NOV RPL39L AHR INSIG1 PDGFRA EPHB2 LSS ENPEP	0.0490692	UP
REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1	CDC20 PSMC6 FBXO5 PSMB8 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 SKP1 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 RPS27A UBA52 BTRC CUL1	0.0492305	DOWN
REACTOME_RNA_POL_I_TRANSCRIPTION	HIST1H2BC HIST1H4H HIST1H3H HIST1H3D HIST1H2AE HIST1H2BH HIST1H2AC HIST1H2BD HIST1H2BG CDK7 HIST1H2BE HIST1H2BI HIST1H2BF RRN3 HIST1H3E GTF2H2 HIST1H2AJ HIST1H2BM HIST1H4K GTF2H1 MBD2 HIST1H4B HIST1H3A MAPK3 HIST1H3F HIST1H2BK HIST1H4J HIST1H4D POLR2H HIST1H2AD HIST2H2AA3 ERCC6 HIST1H4F CCNH HIST1H3B H3F3A POLR1C H2AFX HIST1H4C TAF1A HIST1H2BO HIST1H4L POLR1D HIST2H4A HIST1H4A HIST2H2BE HIST1H3G GTF2H4 HIST1H2BB POLR2K HIST1H2BJ H2AFZ KAT2B HIST1H4E HIST1H4I ERCC3 HIST1H2AB CBX3 HIST1H3I HIST1H3C H3F3B MNAT1 GTF2H3 TAF1B HIST1H2BN UBTF HIST1H2BL HIST1H3J EHMT2 TAF1C ERCC2 POLR1B PTRF	0.0492409	DOWN
LEE_SP4_THYMOCYTE	NR4A2 EGR3 HTR2B IFI44L SERPINE2 IER3 PDE4D DUSP4 SPRY2 CLDN1 RSAD2	0.0492928	UP
ZHAN_MULTIPLE_MYELOMA_SUBGROUPS	TMEM131 MTIF2 UGP2 CDC6 ACO2 EZH2 C1D CKS1B TYMS UBE2V2 SNRPD3 FKBP1A SUMO1 PRKDC MSH2 CSNK2B POLD2 PSMD14 EIF2S1 EWSR1 EIF2B1 XRCC6 SNRPC MAZ PRIM1 CCT4 FNTA RANBP1 CHAF1A DFFA	0.0493375	DOWN
REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0	HSPA1B PSMC6 PSMB8 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 HSPA8 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 PSMB6 PSME2 EIF4G1 PSMD12 PSMB1 PSMD6 PSME1 PABPC1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 RPS27A UBA52 HNRNPD HSPB1	0.0493683	DOWN
PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP	MGP FABP4 REEP1 KIAA1462 TIMP3 PEG10 CH25H PDLIM3 RBPMS APOD CXCL12 LDB2 CDKN1C DCLK1 CSRP2 RAB31 ITGA1 LAMP3 USP13 RELN GPRC5B OLFML2A CD200 LMO2 SPRY1 GMFG RAMP3 CREM ARID5B MRC1 RGS16 RAMP2 CEP68 PDPN SLC26A4 FLT4 HLA-DPB1 CRMP1 RBP1 NPTX2 DUSP5 ITGA9 CETP NR2F1 MEF2C MAF HOXD10 ARRB2 GRAP DYRK3 LYN MYBL2 PYGL TBX1 CALCRL LIPA ANGPT2 CYP1A1 CLEC4M TBXA2R ISG20 MCM6 ANKS1A KALRN PLK1 HMGB2 NOS2 TUBA4A LBR UNC5B HIST1H4C BUB1 PAQR3 PROX1 ALDH1A1 PPP1R2 RAPGEF5 PTTG1 AURKB SPAG5 UBE2C ACSL3 TK1 SOCS2 GAB1 ADD3 SMC4 CTDSPL CDK1 KIAA0101 PRKCZ CCNE2 EMP2 PDLIM1 KIF2C LMNB1 CDKN3 CKS1B CENPF BUB1B NDC80 GCH1 RMND5A FOXM1 MAOA NDRG1 PNP CCNB2 PCSK6 IGFBP2 PDE8A TOP2A SLC39A14 GINS1 CCNB1 DSP CCNA2 KIF11 DHCR24 BTBD3 TTK CEACAM1 TFF3 IQGAP2 IL7 SMAGP PPARG	0.0493789	UP
PARENT_MTOR_SIGNALING_DN	CNN1 ADAM19 ELOVL5 EREG ITGAM FGF2 CD248 TGFB3 RGS16 PDGFB FHL3 CRABP2 SLC26A10 ALMS1 SPN CNTN1 POLR3G HGF MPRIP DUX1 WFDC2 PTCRA SIGLEC7 MYL4 AQP6 FGF5 ANKRD2 RPL12 CXCL3 SSX2IP DNAJC4 KRT86 NRCAM ENGASE VEGFA UBE2D2 SLC12A6 MMP24 EIF5 LSM4 BMP2 CEACAM1 TOX3	0.0493794	UP
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC38A4 SLC3A1 SLC22A4 SLC9A2 SLC9A3 SLC44A4 SLC35A3 SLC4A4 SLC22A5 SLC1A1 SLC16A1 SLC35A2 SLC39A4 SLC39A8 G6PC SLC28A2 HK2 SLC36A1 SLC17A5 SLC26A2 SLC22A18 SLC35D2 SLC5A1 SLC35D1 SLC6A9 SLC20A1 SLC12A2 SLC30A1 SLC33A1 SLC20A2 SLC26A3 SLC37A4 SLC26A6 SLC30A5 SLC31A1 SLC35A1 HEPH SLC2A10 SLC25A10 SLC16A10 NUP37 SLC2A1 SLC9A1 SLCO4C1 SLCO1B3 SLC24A1 SEH1L SLC35C1 SLC39A2 SLC16A3 SLC13A1 SLC12A1 NUP85 SLC12A6 SLC2A5 NUP50 SLC2A9 SLC9A8 SLC15A2 SLC38A1 NUP107 SLC17A6 RAE1 SLC44A1 NUPL2 NUP155 SLC7A9 NUP153 SLC29A2 NUP133 SLC24A2 NUP43 SLC2A4 SLC9A6 SLC12A7 SLCO1C1 SLC22A3 NUP88 SLC7A1 RANBP2 SLC5A5 G6PC3 SLC6A20 SLC7A6 SLC39A7 SLC5A7 NUP205 SLC1A5 NUP54 SLC5A6 SLC22A2 SLC7A8 SLCO2A1 SLC14A1 SLC6A3 SLC29A3 SLC34A2 SLC39A1 ALB NUP214 SLC18A1 SLCO2B1 SLC1A7 SLC18A2 SLC11A1 TPR SLC13A2 SLC8A1 SLC30A3 SLC7A11 SLC6A14 HK3 NUP93 RHCG SLC22A11 SLC5A2 SLC1A2 SLC4A1 SLC4A5 SLC7A2 GCKR SLC1A6 SLC28A1 SLC14A2 SLC6A7 RHAG SLC7A7 SLCO4A1 SLC2A8 AAAS SLCO1A2 SLC28A3 SLC1A4 SLC15A1 HK1 SLC2A11 POM121 SLC22A1 SLC16A8 SLC22A7 SLC26A1 G6PC2 SLC22A6 SLC9A5 SLC6A5 SLC6A12 SLC9A7 SLC34A1 SLC6A11 SLC38A3 GCK SLC4A8 NUP188 SLC6A6 NUP62 SLC3A2 SLC13A3 SLC12A4 SLC6A15 AVP SLC17A1 SLC6A2 SLC43A1 SLC2A2 SLCO1B1 SLC6A1 SLC4A2 SLC12A5 SLC17A7 SLC38A2 SLC4A3 SLC22A8 SLCO3A1 NUP210 SLC39A6 SLC27A6 SLC4A7 SLC2A6 SLC8A2 SLC26A4 SLC7A10 SLC2A3 SLC1A3 SLC16A7 SLC47A1 SLC7A5 SLC29A1 CP SLC15A3 SLC24A3	0.0494666	DOWN
HU_GENOTOXIC_DAMAGE_4HR	ECT2 PRC1 NEK2 CDC25C AURKA ALAS1 CDC20 CKS2 ORC5 KIF22 CDT1 PTTG1 KPNA2 H2AFX BUB1 HMGN1 SMG5 SYNCRIP TNNC1 MAPRE1 TRAFD1 HIST1H2AB CUL1 IFNAR2 TIMP2 JUND NCDN ITGB7 MTHFD2	0.049607	DOWN
REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C	PSMC6 PSMB8 PSMD3 PSMA5 CDC23 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 UBE2D1 PSMC4 PSMD8 PSMA6 UBE2C PSMF1 PSMD5 PSMB3 UBE2E1 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSMD14 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 CDC27 ANAPC5 PSMB4 PSMB9 ANAPC1 PSMB2 CDC16 PSMC2 PSMC5 PSMD4 PSMC1 RPS27A UBA52 ANAPC10 ANAPC2	0.049725	DOWN
ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP	FAM129A ARMCX1 MAP1B G0S2 RAB31 PHGDH CORO1A RAB33A ITGAL SLC7A5 TM6SF1 STOM CEBPB SLA RBP1 KIF21B TRAF3IP3 TBC1D16 MTHFD2 STC2 WARS INHBE TRIB3 WFDC2 NPAS3 EIF4EBP1 KCNK12 DCC ATF5 KLHL4 ASNS GPR63 SLC7A11 USP32 DNAJC12 NID2 ADRB1 HS3ST3B1 RTN3 TPBG ASS1 KLF4 VLDLR PCK2 HADH CEBPG GALNT3	0.0498093	UP
VETTER_TARGETS_OF_PRKCA_AND_ETS1_UP	PEG10 TRPC1 FN1 ARL4C BCL11A PML TGFB2 INSIG1 HS2ST1 UBAP2L SCAMP1 DIAPH1 RUNX1 SEC23IP RHOBTB3	0.0498186	UP
TURJANSKI_MAPK14_TARGETS	FOS MEF2C ELK4 DDIT3 TP73 STAT4 ELK1 MEF2A TP53 ATF2	0.050048	UP
MCCLUNG_COCAINE_REWARD_5D	EGR1 CTGF STXBP1 PDE4B ELN SPOCK2 PENK ACTN1 CORO2B FSCN1 ST6GALNAC5 FMNL1 NRGN CELF2 H1FX PALM ATP1B2 VAMP2 TUBB4A NELL2 KCND2 C20orf27 ADORA2A CACNA2D3 SYP PDE1B SH3GL3 BAIAP2 MTMR9 POU2F1 KRT16 SEC14L1 DLG4 FBXW7 MAPRE3 GRIA4 SOX10 SMARCA2 ADORA1 BTRC GRIA1 UNC93B1 OAZ3 CCK PER2 CAMK2A LARP1 HPS4 ACTL6B CD47 GAD1 NPTN TBR1 HSPA5 WBP11 USP53 DNAJB9 PTP4A2 ACTR2 GADD45A BZW2 TMEM50B KIF23 ITFG1 TM9SF3 GOLGA4 MARK2 KLF13 SDHC JUP TOP2A TSPAN7 NCBP1	0.0501588	UP
BIOCARTA_IL17_PATHWAY	CD2 CD4 CD34 IL6 CD3D CD3E CD247 CD8A CSF3 IL3 IL17A KITLG CD3G CD58	0.0501865	UP
LIU_PROSTATE_CANCER_UP	AMACR GOLM1 GMDS ENTPD5 GJB1 MAP2K6 MYO6 GALNT7 ECI2 FBP1 EPCAM CANT1 CLDN8 TRPM4 ST14 SOX9 RAB17 TRIM68 ABCC4 ENTPD6 REPS2 LYPLA1 UAP1 IMPA1 GGCT SOX4 CREB3L1 TSPAN13 CAMKK2 SLC19A1 CCNG2 EIF2AK1 AKR1A1 PDLIM5 BZW2 TARP GADD45G PDIA5 SEL1L HPN CALR TBC1D4 APRT SERP1 PPP3CA PYCR1 NLE1 MARCKSL1 EIF4A1 PPP1R14B TMEM161A OR51E2 HIST3H2A PPP1R9A TP53 SRPRB RAP1GAP ELK1 SIM2 FARP1 HOXC6 ATF6B RAB3D PPM1E SLC43A1 RNF41 PTP4A3 LRIG1 MTHFD2 TRIB1 BCAM ALDH1A3 GDF15 ARHGEF26 CADM1 GUCY1A3	0.0504274	DOWN
LEE_TARGETS_OF_PTCH1_AND_SUFU_DN	SYT1 GUCY1A3 PPP1R3C NRXN3 NCAM1 NDRG4 ITPR1 DCLK1 PTGDS RCAN2 SPOCK2 PENK NEFH THY1 NTM FNBP1 TSPAN2 MAP4 PCSK1N SEMA3E VAMP2 ATP2B2 GJA1 KCND2 RAB3A KIF1A LRP8 CEND1 PRKCG CSDC2 TRPC3 CA8 SLC13A3 MASP1 MAPRE2 MAPRE3 CALB1 CACNA1G HK1 GRIA1 CBLN1 SLC1A6 CNP SLC4A10 SLC8A1 NRIP3 SEZ6L2 GRM3 CLSTN2 KIF5A GAD1 DYNLT3 PREPL ABLIM1 ATP2A2 TMEM50B ZIC3 VSNL1 ATP1B1 PDXK RAB4A ASPH HMGCS1 ITPKA KCNK1 PAK1 CDS1 CKMT1B PTPRR	0.050654	UP
BIOCARTA_TPO_PATHWAY	FOS JUN STAT5B PRKCB PIK3CG PLCG1 STAT5A PRKCA PIK3CA THPO MPL PIK3R1 STAT3 HRAS SHC1 JAK2 RAF1 MAP2K1 STAT1 GRB2 RASA1 MAPK3 SOS1 CSNK2A1	0.0509064	UP
JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_DN	CRYAB IGFBP5 CLU PLP1 DCN SPARCL1 CHN1 SPARC CALY NDN IGFBP4 GJA1 PLA2G7 PFKM ALDOC NCDN CSDC2 GRINA LDHB TEF LRP1 GNAS ACSBG1 CST3 CAMK2G CALM1 HDAC11 ITM2B GSTM1 CLSTN1 MAT2B QDPR NDRG2 FTH1 PYGB ACOT7 ATP2A2 ATP1B1 CTSD GHITM NSF PLEKHB2 NDRG1	0.050968	UP
ZHENG_RESPONSE_TO_ARSENITE_DN	ADAMTS1 CXCR4 FOXC1 CEBPD MYC PTPN11 JAK1 MMP3 INSIG1 TFAP4 MMP13 TPR IL1A CENPE WNT5A	0.0509737	UP
REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING	AKT3 FYN LCK MAP3K14 CD86 CD28 PIK3R3 MAP3K8 PIK3CA TRIB3 AKT2 AKT1 PIK3R1 MAPKAP1 MTOR CD80 PIK3R2 PDPK1 MLST8	0.0510121	UP
BIOCARTA_AMI_PATHWAY	TFPI COL4A1 COL4A2 PROS1 F10 FGB PROC AHSP COL4A4 FGA F2 COL4A5 F7 SERPINC1 FGG COL4A3 PLG COL4A6 PLAT F2R	0.0510278	UP
PID_CD8_TCR_DOWNSTREAM_PATHWAY	FOS EGR1 JUN JUNB TNFRSF9 NFATC1 PRKCB CD3D PTPN7 CD3E CD247 PRKCQ IFNA10 IFNA4 IL2RA CD8A IFNA16 PRKCA PPP3CB IFNA6 IFNA7 IFNAR2 FOSL1 IL2RB IFNA21 IL2RG NFATC3 STAT4 CD8B IFNA8 FASLG TNFRSF4 PRF1 IFNA14 ELK1 EGR4 PPP3R1 IFNA2 PRKCE HRAS MAPK8 GZMB RAF1 MAP2K1 BRAF IFNA17 IFNA1 B2M IL2 CD3G PPP3CA IFNG IFNAR1 HLA-A IFNA5 MAP2K2 TNF MAPK9 MAPK3 KRAS MAPK1 NRAS	0.0510423	UP
WESTON_VEGFA_TARGETS_3HR	MGP CCL2 NNMT NR4A1 RHOB CXCR4 PDE4B TIE1 EFEMP1 ELN GJA4 VCAM1 ISL1 LMO2 HCLS1 ICAM2 VWF ZFHX3 BGN CD34 CXCL1 PIM1 TFPI2 GSTT1 PGF FOXO1 ANGPT2 KDR SHC3 MMP3 MPHOSPH10 RANGAP1 ADD2 ESR1 MMP10 SLC6A8 BMP4 KRT7 RBX1 BMP6 BCKDHA TRIM23 HEXA DYNLL1 ANKRD1 IL32 NDUFA1 SULT1E1 SP3 SAT1 AQP7 GALNT1 PRKCI FUCA1 UNG CD9 TNFSF10 PNP IFI27 PIR GCHFR MMP1 RALA CEACAM1 HSD11B2 FGFBP1 F2RL1 MRPL19 GGH	0.0510717	UP
KEGG_CHEMOKINE_SIGNALING_PATHWAY	CCL2 CCL21 CXCR4 CXCL13 CCL11 CXCL12 CCL19 AKT3 CCR7 PLCB1 ELMO1 CCL3 TIAM1 GNG11 CXCL2 GNB5 CX3CL1 DOCK2 CCL18 GNG3 STAT5B ITK CCL22 ADCY2 PIK3CD CCR10 GNAI2 PRKCB RAC2 CCR6 GRK5 CCL4 CX3CR1 RASGRP2 ADCY7 PPBP CXCR5 CXCL1 CCR1 FGR CCR2 SHC2 PIK3CG NCF1 VAV1 CCL20 CCR4 GRK1 CCL17 CCL14 GNG7 ARRB2 PIK3R3 PRKACG NFKBIA LYN CXCR2 PIK3CA ADCY3 PLCB2 CCR5 XCR1 CCL27 RELA ADCY8 XCL2 CCL25 PRKACA CXCR6 AKT2 WAS ROCK1 GRK6 CCR9 IKBKB GRK4 GNB3 SHC3 STAT2 AKT1 CCL16 PF4V1 PIK3R1 HCK GSK3A IKBKG CXCL9 CXCR3 JAK3 CCL23 PIK3R5 CXCL3 PTK2B GNG4 XCL1 CSK CCL5 RAP1A GNB1 STAT3 HRAS PIK3R2 PARD3 CCL1 ADCY1 PTK2 CXCL10 VAV2 FOXO3 GNG13 CCR3 SHC1 CCL8 PLCB3 CCR8 CCL7 JAK2 TIAM2 RAF1 MAP2K1 STAT1 BRAF GRB2 CXCL5 RAP1B GNB2 RHOA NFKBIB CXCR1 PXN GNGT1 CXCL14 CCL24 NFKB1 PF4 GNAI3 RAC1 CDC42 MAPK3 CRKL GNG5 ROCK2 SOS1 CXCL11 PRKX CRK PRKCZ CXCL6 ADCY9 GSK3B PRKACB KRAS ARRB1 PRKCD SOS2 CHUK PIK3CB MAPK1 ADCY6 GNG12 CCL13 PLCB4 PAK1 VAV3 GNAI1 NRAS WASL CCL15	0.051097	UP
REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX	GMNN ORC2 CDC6 ORC5 ORC4 CDT1 ORC1 E2F2 E2F3 ORC3 RPS27A UBA52 E2F1	0.051396	DOWN
BIOCARTA_CTCF_PATHWAY	TGFBR3 TGFB1 CD79B CD79A TGFB3 MYC PIK3CG TGFBR2 PIK3CA TGFB2 CDKN2A PIK3R1 TGFBR1 MTOR TP53 MDM2 CDKN1B PPP2CA SMAD5 PTEN RPS6KB1 SMAD1 SMAD4	0.0514448	UP
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP	STEAP1 ASPM PLEK2 ECT2 MAD2L1 HMMR PRC1 AGAP1 RFC5 CENPA GMNN KIF11 CCNA2 CEP55 CCNB1 TOP2A DTL UCK2 ZWINT SLC20A1 STIL CORT CAMK2N1 MKI67 DHFR F3 CPT1A CDC6 NDC80 FABP5 HELLS CKS1B GGCT CDC7 FBXO5 HSPE1 PLK4 CENPE KIF23 RAD51 TMPO CIT ESPL1 ASF1B YEATS4 MCM4 MBOAT7 FHL2 NT5E HIST1H4B MCM2 CD164 CDK1 PGK1 TFDP1 RFC2 BRCA1 TYMS HIST1H4J IDH2 TIMM10 RUNX1 MFHAS1 YWHAH H2AFY RBM14 BCL2L11 ENO1 RFC3 MT2A PCNA ANKRD1 NUP155 MSH2 H2AFX BUB1 HIST1H4C CRY1 ORC6 RRM2 POLD3 MCM7 PAK6 ARPC5L CALM3 CDK2AP1 TNK1 UGGT2 PLK1 ENOPH1 STAMBPL1 TUBB4B KNTC1 ARPC1B YRDC POLR3K ENC1 PRIM1 SERPINB2 TUBG1 CCT4 PRR4 DIAPH3 CDC45 CDK2 SDF2L1 PKMYT1 STK17A MCM6 UBE2S DSCC1 EXO1 RAD51B VCAN MCM5 RTEL1 BRIX1 BLM RRS1 STMN1 RECQL4 PLAUR TUBA8 DCK MCM3 MMP14 E2F1 RBL1 HOXC13 CRLF3 CYP2A13 TUBB3 TGFB2 EIF5A2 ODC1 FOSL1 PHLDA1 RFC4 TACC3 IGFBP3 FBXO41 FJX1 TNFRSF12A BARD1 TUBB PLCG2 ETV1 SERPINE2 FGF2 AKAP2 SMTN MYBL1 TUBA1A VEGFC	0.0518179	DOWN
REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10	MAVS CHUK TRIM25 FADD RIPK1 IFIH1 CASP8 CASP10 DDX58 IKBKG IKBKB	0.052131	DOWN
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN	SLC16A1 TDP2 CHEK1 RNF7 KLF13 MRPS12 AIMP2 EZH2 RACGAP1 CDC23 EBNA1BP2 C1QBP LSM4 IREB2 MCM2 CDK1 TYMS PSMD8 G3BP1 LSM5 IP6K2 AASDHPPT SLC38A1 CCT5 TMEM165 NCAPD3 KEAP1 PRKDC RPL26L1 NDUFA13 CHMP4A FIBP CYP2R1 LAP3 DKC1 DDX1 THYN1 CCT2 SSBP1 IK ASF1A IARS RAN TIMM50 NASP TBCB NMT1 PAAF1 CEP152 RFX7 EIF3G PPP1R12A BARD1	0.052386	DOWN
REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	MYL9 MYH10 MYH11 RHOB RAC2 SEMA4D LIMK1 RHOG ROCK1 RND1 MYL6 MYH9 RHOA PLXNB1 MYL12B RAC1 CDC42 ARHGEF11 ROCK2 ARHGEF12 MYH14 ERBB2 LIMK2	0.0525576	UP
BURTON_ADIPOGENESIS_3	NQO1 MTM1 MAD2L1 PRC1 KLF5 RFC5 KIF4A TTK KIF11 AURKA CCNB1 DLGAP5 TOP2A DTL KIF20A MAN2A1 CDC20 RAD51AP1 CCNB2 PNP MKI67 CKS2 CDC6 EZH2 CSTF2 HELLS CKS1B CDC7 SMC2 IL13RA1 RAD51 NUSAP1 KIF2C RACGAP1 CCNE2 ASF1B KIAA0101 TOPBP1 KIF22 MCM4 CDCA8 MCM2 CDK1 TFDP1 BRCA1 TYMS TK1 LRP5 BIRC5 BZW1 NCAPH KPNA2 ILF2 PCNA RRM1 BUB1 POLA1 RRM2 MCM7 DTYMK SLBP HMGB2 PLK1 FEN1 USP1 IMPDH2 MCM10 PRIM1 INCENP CDC45 HIST1H2AB VCAN MCM5 GAS6 ABCA1 NASP TRIP13 DCK CCNF MCM3 DNMT1 WNT4 ADAM8 HGF TACC3 SLCO3A1 LMO4 AQP1 OSMR PTGFR CX3CL1 TNXB CSRP2 NID1 TUBB6	0.0527074	DOWN
RADMACHER_AML_PROGNOSIS	SRPX GUCY1A3 TMEM158 PMP22 MAL PBX3 ANGPT1 TGM2 GYPC S1PR1 TUBB2A COL1A1 FGFR1 HOXB2 RGS16 CTNNAL1 TCF4 DAPK1 NR2F2 CD3D PMEPA1 HOXA4 DENND4B BCL11A TBXAS1 PLCG1 IL6ST SEMA3F FLT3 PXDN TSPAN32 DMWD PRG2 FOXO1 AGRN GLUL WDR82 SLC7A7 ISG20 FARP1 BAHCC1 NFIB PIK3R4 UGCG SLC6A8 UGGT2 TACSTD2 CNN3 CDC42EP4 S100P NFKBIB NBL1 NFKB1 HOXB5 EZR SFTPB FHL2 SLC2A1 SKAP2 ENDOD1 LCN2 HOXA10 PLIN2 EML4 SMG1 IFI27 TSPAN7 SELENBP1 AGT MAP7	0.0527481	UP
BIOCARTA_INTRINSIC_PATHWAY	SERPING1 F8 COL4A1 COL4A2 PROS1 F10 FGB KLKB1 PROC F5 F11 COL4A4 FGA F2 COL4A5 F9 SERPINC1 FGG COL4A3 COL4A6 KNG1 F2R F12	0.0527569	UP
URS_ADIPOCYTE_DIFFERENTIATION_UP	FABP4 CRYAB ADIPOQ CAP2 DPT ECM2 FXYD1 PCDH7 LPL KCNH2 PTPRZ1 PFKFB3 CTSG PLIN1 TNFAIP2 ATP8A2 STAT5B PLEK MTMR12 ATP2B2 MSTN COL7A1 LBP SKAP1 DGKG LIPE C1orf61 MMP7 LRP8 ALDH1A2 APLNR APOB GPD1 MASP1 DPF2 SPTBN4 E2F1 GLUL RXRB PTPRS CHST1 FABP7 ABCE1 SMARCB1 CIR1 VTN TFCP2 ACSL1 SLC24A2 MAP4K3 TAP1 PLCD1 RXRA INSR AMT USP8 MTUS1 ACOX3 FABP5 LYPLA1 IL22RA1 PLIN2 DGAT1 IGFBP2 LIPC ALDH6A1 HSD11B2 AGT PPARG ADORA2B	0.0527664	UP
REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	GALNT3 GALNT12 MUC2 GCNT3 GALNT7 GCNT1 MUC5B B4GALT5 B3GNT3 MUC4 C1GALT1C1 MUC13 B3GNT2 GALNT1 GALNT10 ST6GALNAC4 C1GALT1 GALNT2 MUC7 MUC5AC GALNT8 MUC16 ST6GAL1 B3GNT4 GALNT6 B3GNTL1 MUC6 GALNT11 GCNT4 ST3GAL2 ST3GAL1 GALNT14 ST6GALNAC2	0.0529311	DOWN
FAELT_B_CLL_WITH_VH_REARRANGEMENTS_UP	EGR3 TUBA1A SCRN1 EMP3 GABBR1 RAB31 BCL6 CLIC4 NCF4 CBFA2T3 DUSP7 TBL1X FGL2 ADORA2A DENND4B DGKG N4BP2L1 BMI1 MNT TLR1 FOXO4 CDKN2D CACNA1A NPC2 ARFRP1 MTSS1 HNRNPA3 ING1 JAK2 NPTN SPEN SUN1 CPT1B SAP18 SRSF2 RAB6A RUNX1 EFR3A HLA-F CTDSP2 ID3 CAPZA2 PLAGL1 MXI1 YIF1A PIP5K1B	0.0529708	UP
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN	C8orf4 PPP1R3C RUNX1T1 SORBS2 KANK2 DUSP10 HEY2 LMO2 FAM49A EVI2B PCDH17 PDGFB FOXC1 GRAP PPAN IFIT1 LYPD1 TBX1 TNK2 FZD8 GBP1 TFAP2A NYNRIN GJA5 IFIT5 SH2D3C STAT1 ZMYND8 EXOSC4 IFIT3 RAPGEF5 AURKB SMAD7 STK38L METTL7A PGRMC2 LIPG ARL4A MT1F SOX4 CROT MECOM RHOBTB3 RPRD1A HOXA5 PLIN2 AGPS	0.0533919	UP
NIELSEN_LEIOMYOSARCOMA_UP	LOXL1 VEGFC AIM2 HLA-DQB1 MME COL7A1 MTR HOMER2 PLOD1 SLAMF8 CXCL9 PLEC CCL5 KCNN4 SH3BGRL3 CAPG MICAL2	0.0534538	UP
MALONEY_RESPONSE_TO_17AAG_UP	MYL9 CAP2 NEFM PLTP SERPINB9 HTR2B PCOLCE UCP2 CTSH IFITM2 SOX12 MNDA SERPINH1 TAF1C CCL14 KLF10 CPZ KCNB1 KSR1 PTPRU SPTAN1 SMARCC2 HSP90AB1 ST13 EEF2 ATP5G2 STAT6 STX5 PDAP1 UBA1 HSPA8 TAF10 SLC25A6 TARBP2 ARPC3 EPHA1 CAPN1 MRPS6 IGFBP2 NFIL3 HSPA1B	0.0535016	UP
LOPEZ_MESOTELIOMA_SURVIVAL_TIME_UP	KIF4A CDC25C AURKA MELK HN1 FLNB ACOT7 BIRC5 MBOAT2 FAM64A DCLRE1B TRIP13 PLXNA3	0.0536575	DOWN
BARRIER_COLON_CANCER_RECURRENCE_DN	BSG TSPAN7 ASB13 ACOT11 EPPK1 CTSA CD24 SPPL2B PFKL FOXJ3 CITED2 HLA-C NUCB1 NDFIP1 BTBD2 CDK10 AES STAT2 ARHGAP33 KCNAB1	0.053815	DOWN
BURTON_ADIPOGENESIS_PEAK_AT_24HR	HMMR PRC1 AGT CCNA2 CDC25C MELK CCNB1 TOP2A KIF20A CDC20 SLPI LCN2 NUSAP1 DCTPP1 RACGAP1 KIF22 CDK1 TK1 UBE2C AURKB PTTG1 KPNA2 SRSF1 RRM1 H2AFX BUB1 EXOSC5 ELAVL1 IPO5 RANGAP1 C9orf16 CAD STMN1 SNRNP70 GALK1 ISYNA1 AQP1 S100A8	0.0544535	DOWN
APPIERTO_RESPONSE_TO_FENRETINIDE_UP	CYR61 MGP UCHL1 NID1 PDZD2 GDF15 ITGAX CYB5R1 SRR TM4SF1 BRD2 MMP3 RRP12 CCNL2 GAD1 TSC2 AHSA1 KRT6B PSMA7 HSPA8 ZNF672 HSPA4 ABHD4 FOXJ3 SDC4 PSMC4 CCNJL PRKACB STXBP3 TFRC MYO1E CCL13 AKAP9	0.055033	UP
KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	DES TPM2 DMD ITGA7 ITGA5 TGFB1 ITGA1 SGCD SGCA ACTC1 LAMA2 IGF1 TGFB3 ITGA4 CACNA1C IL6 RYR2 ITGA9 CACNA2D1 PRKAA2 CACNA2D3 SGCG TNNT2 TPM1 ITGB7 MYL3 CACNG1 CACNB2 EMD CACNB4 TGFB2 CACNG3 ITGA2B TPM4 CACNG2 TNNI3 MYL2 CACNG5 CACNG4 CACNA1D MYH7 CACNA2D2 TPM3 ITGA8 ITGA10 ITGB8 ACE ITGB1 SLC8A1 ACTB TTN LMNA ITGB3 TNNC1 MYH6 DAG1 MYBPC3 SGCB CACNA1S ACTG1 ITGA3 CACNB3 CACNB1 ITGAV PRKAG1 ITGB5 CACNA1F TNF ITGB4 PRKAG2 ATP2A2 PRKAB1 ITGA6 ITGA2 PRKAB2 PRKAA1 ITGB6	0.0550655	UP
NIELSEN_SYNOVIAL_SARCOMA_UP	OLFM1 NPTX2 APBA2 KIF1A PRAME CPA3 TGFB2 COL9A2 RGS6 ECEL1 COL2A1 KCNQ2 ENC1 VEZF1 TLE3	0.0553961	UP
PUJANA_BRCA_CENTERED_NETWORK	MAD2L1 HMMR TTF2 CCNA2 AURKA GINS1 TOP2A CDC20 RAD51AP1 TFDP2 DHFR RBBP8 NCK1 MED20 EZH2 NDC80 SKP2 CDC7 SMC2 CSNK2A1 UNG LMNB1 PAICS TMPO IDH3B NCAPD2 ESPL1 TOPBP1 METAP1 MCM4 MCM2 CDK1 TFDP1 SMC4 BRCA1 TAF11 CHEK2 ZNHIT3 BRCA2 RPIA SNRPA1 UBE2C ABCB7 MRE11A DDX46 PPP1CC ZNF330 RFC3 PCNA PRKDC MSH2 SMC1A RRM1 TOP1 SMC3 DEK RAD21 TIMELESS SLC7A1 NAE1 FANCI POLA1 RAD1 LBR BUB3 KATNA1 DCP2 H2AFV COPS3 RB1 HMGB2 RBBP4 SNRPB POLR2B DNA2 PRPF4 TCERG1 RPA1 ASF1A SEC31A PPP2R5C MAT2A SRSF11 TBCA RAD54L EIF3H SUZ12 MCM6 POLE XPO1 MCM5 CNOT3 DUT SNRPA CPSF4 CAD CHAF1A RNASEH2B DDX39A BLM AATF NASP KIFC1 DNMT1 TCF3 RECQL MYBL2 RFC4 NFYB STAT5A RAD51C ATM SSBP2 PRPS1 PSIP1	0.0562265	DOWN
MANN_RESPONSE_TO_AMIFOSTINE_DN	MAD2L1 CCNB1 TWF1 KRAS PRKACB RRM2 HNRNPK HMGN2 XPO1 BLMH	0.0563103	DOWN
BURTON_ADIPOGENESIS_6	ETFDH PXMP2 LIAS BCKDHB CA2 RETSAT HIBCH TST GSR HADH SFXN1 ACAA2 ACADS SLC25A1 ALAS1 CBR1 DHRS7B GSTZ1 PGM1 NDUFS1 DLAT DECR1 SCD DDT MPDU1 ADCY6 SDHB SDHC TSPAN12 PCYOX1 DGAT1 ITGA6 NDUFB7 GBE1 DLD CHPT1 PON2 CYB5B SLC25A5 SUCLG1 PARM1 NDUFA9 DNAJC15 NR1H3 SDHA NDUFB3 CAT ATP5D HSD17B4 ME1 NDUFS3 UQCRC1 LCN2 UQCRC2 ISCA1 COX5B HADHB CHCHD3 SCP2 PEX19 NDUFB6 MCCC1 DLST MGLL UQCRQ GCSH SLC25A10 SLC19A1 HSD17B12 ISOC1 CCNG2 NDUFC1 CYB5A NDUFB5 COX7B ARL4A AQP7 AGPAT3 COX7A2 ALAD TKT CS DHCR7 NDUFA5 UQCR10 PPP2R5A TUFM BCAT2 SCARB1 SAMM50 ATP5O FAH RNF11 QDPR CA3 RTN3 ORM2 ACYP2 NDUFB8 SLC2A4 CIDEC PDHB CD151 FASN PDAP1 FXN OGDH GDF5 CIB2 TANK KAT2B UQCRB S100A1 LONP2 PSAT1 HIPK2 PSEN2 PHTF2 REEP5 PLA2G6 C9orf16 HP PNPLA2 ABCA1 ACADL FAM49B ORM1 RAB3D MC2R PEMT UNC119 ABCD2 RETN CD1D LDHB DBT GPD1 EHD1 CAMP APOE C20orf27 IMPDH1 LTC4S CDKN2C RARRES2 HSD11B1 APOC1 MAP4K4 LUM SGCD S100A8 COL15A1 BNIP3 MCAM G0S2 QKI LPL CFD RBPMS NNMT SDPR AOC3 ADIPOQ	0.0563208	DOWN
SHIN_B_CELL_LYMPHOMA_CLUSTER_9	NKX3-2 PAX5 CD19 CD79A CXCR5 CD40 HOXA4 BCL11A GATA1 TAL1 REL S100A9 SPIB IRF8 TLX1 WNT2 MMP13 IKZF3 HMGB3	0.0563701	UP
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION	MYL9 CXCR4 CXCL12 CDH5 CTNNA2 JAM3 MMP9 JAM2 RHOH VCAM1 ITGAM MSN THY1 PECAM1 ITGB2 ACTN1 ITK NCF2 PIK3CD ITGA4 NCF4 CLDN5 ITGAL GNAI2 RAPGEF3 ICAM1 PRKCB RAC2 PLCG2 MAPK12 MMP2 CYBB PIK3CG NCF1 VAV1 CLDN10 SIPA1 PLCG1 PIK3R3 VCL PRKCA ACTN2 PRKCG PIK3CA CLDN11 MYL7 CLDN17 CLDN9 CTNNA3 ACTN3 MYL10 CLDN6 PTPN11 MYL2 ROCK1 RAPGEF4 CD99 PIK3R1 MYLPF MAPK11 PIK3R5 ITGB1 PTK2B CLDN14 ACTB TXK CLDN16 RAP1A CLDN18 PIK3R2 PTK2 VAV2 CTNNB1 VASP NOX3 RAP1B ACTG1 MYL5 CLDN1 RHOA PXN ARHGAP35 CYBA MYL12B GNAI3 RAC1 MYL12A ACTN4 EZR CDC42 ROCK2 MAPK14 CLDN15 CTNNA1 ARHGAP5 CLDN3 PIK3CB CTNND1 CLDN8 CLDN4 F11R NOX1 VAV3 GNAI1 CLDN7 MAPK13 OCLN	0.0565856	UP
ZHANG_TLX_TARGETS_DN	CRYAB NR4A1 S100B EFHD1 RPRM PDE2A PYGM DNAJB5 S100A4 SORBS1 GSTM5 OLFM1 CSPG4 SIRPA BTG2 SOD3 TGFB3 CYTIP DDIT4 NNAT CTSF PHLDA3 NACC2 STOM AOX1 AEN TGFBR2 CDH13 SLC19A2 SP110 CRLF1 PTP4A3 ENO3 GSN APBA2 GABARAPL1 SLCO3A1 PLEKHF1 SPHK1 KIF1A PLD3 ZMAT3 TM4SF1 TIMP2 DUSP3 RALGDS YPEL5 DDIT3 HIST1H2BL CSF1 TTLL1 S100A11 MXD4 NFKB2 BTG1 KCNC1 PRMT2 GADD45B RPL18 HIST3H2A TSC22D1 PDGFA AK1 TCN2 EPHX1 GADD45G CITED2 C14orf159 PARP3 TAP1 ABHD4 CCNG1 PLCD1 PTPRE CYP3A4 TCTA SAT1 S100A10 BAX KLF4 CDKN1A FCGRT TOB1 TAX1BP3 GDPD2 CPPED1 DCXR PGPEP1 SCARB2 VWA5A OPN3 HIST1H1C GDPD3 HIST1H2BC	0.0567817	UP
PID_GLYPICAN_1PATHWAY	SLIT2 TGFB1 PRNP FGFR1 FYN FGF2 LCK TGFB3 BLK FGR GPC1 TGFBR2 LAMA1 LYN TGFB2 NRG1 FLT1 HCK TGFBR1 SERPINC1 PLA2G2A SRC VEGFA APP SMAD2 YES1 TDGF1	0.0572752	UP
HECKER_IFNB1_TARGETS	EGR1 MYL9 CLU CCL2 EGR2 SERPING1 G0S2 STAP1 MMP9 TCL1A MS4A4A LAMP3 SPON2 C1QA OAS2 LY6E IFI44L IFI44 PROS1 C1QB HERC5 CD163 IFI6 MX2 TNFAIP6 C3AR1 MMP25 LILRA3 IFIT1 ZBP1 MX1 ARG1 ITGA2B ISG15 SIGLEC1 CABP5 TYMP GP9 DHX58 CHI3L1 GBP1 IRF7 FFAR2 XAF1 RPS23 IFIT5 CXCL10 GZMB FCER1A CCL8 KLRD1 DDX58 KCNJ15 OAS3 EIF2AK2 STAT1 HERC6 IFIT3 LAP3 IFI35 RTP4 PARP12 IFIT2 PLSCR1 TMEM140 LGALS3BP MGAM SAMD9 SCO2 JUP IFI27 DDX60 APOBEC3A CYP4F3 PDZK1IP1 OAS1 OASL RSAD2 APOBEC3B	0.0573468	UP
REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC	NQO1 PSMC6 PSMB8 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 OAZ1 PSMD14 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 AZIN1 OAZ3 ODC1 OAZ2	0.0575351	DOWN
REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	CD79B FYN CD19 CD79A BLK PIK3CD BTK PLCG2 VAV1 PLCG1 LYN ITPR2 PIK3R1 STIM1 CBL SHC1 CALM1 GRB2 CALM3 CALM2 CBLB SYK SOS1 BLNK ITPR3 NCK1	0.0576881	UP
FINETTI_BREAST_CANCER_KINOME_GREEN	LCK ITK BTK PRKCB MAP4K1 FGR PRKCQ ZAP70 PIM2 LYN STK10 HCK JAK3 SYK STK17B	0.0582136	UP
LINDSTEDT_DENDRITIC_CELL_MATURATION_C	RGS1 ATF3 FERMT2 COL14A1 SYNGR3 ZEB1 NID1 CCR7 S1PR1 TUBB2A C10orf10 CD200 PIAS3 CX3CL1 PRKAR2B GPR171 CD86 ARID5A HLA-DPB1 MMD IGFBP4 STAT5A FLT3 N4BP2L1 TBC1D8 FOXO1 TCF3 JAK1 TRADD SEMA7A ALOX15B MCM5 TRAFD1 PTPN1 STAT3 IL4R TRIP10 UGCG TNFSF4 IGF1R MUC1 KIF2A GTF2E2 POLR2E SOCS2 ROCK2 CAPG CYB5A TOPBP1 GRSF1 CTNNA1 MGLL TNFRSF11B PLAGL1 ALDH2 CLC FGF9 TFRC LY75 LGALS9 ENPP4 LAD1 STK39 NFIL3 CASP3 TNFRSF11A ANXA3	0.0582391	UP
LEE_LIVER_CANCER_MYC_TGFA_DN	NETO2 ABCG2 ACOX1 CYP4F2 PXMP2 CPT2 OTC AQP8 PCK1 EPHX2 ABAT G6PC C4BPA LIPC GOT1 FABP1 NR1H3 CRISP2 EGFR OAT TNNC2 CA3 ALDH1A1 ORM2 HSD17B10 IL1RAP FABP2 CYP2F1 KLF15 MCM10 HAL SLC25A22 PSEN2 BHMT BAAT KHK HPD AASS ALAS2 ORM1 CYP7B1 MAPKAPK2 IGFALS DCT CA5A ETNK2 HAO1 SLC27A5 PTP4A3 MMD GPR37 HSD11B1 HLA-DMA RGN RGS16 TRPV2 IGF1 KYNU TDO2 ELOVL5 G0S2	0.0583818	DOWN
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN	FABP4 ADIPOQ AOC3 NNMT PTRF LHFP TSC22D3 THBS4 CRIP2 CXCL12 SDC2 CFD CDO1 KIF5C EFHD1 G0S2 ARHGEF3 OAS2 ARHGEF6 ENAH RBP4 CBX7 CCDC28B TCF4 PHACTR1 SAP30 SAMHD1 EPHA2 SLC7A10 LTBP2 CDC42EP3 NFIC SETD5 FAM63B TTC9 PLEKHF1 SNCG SLC23A2 MAPK8IP1 TRAF1 THAP3 NOTCH1 SLC6A2 ENTPD2 TNNT3 TXLNA TXNIP HP1BP3 GRTP1 RIMS3 AMY1A GPC4 SP100 IQCC SRSF4 REEP5 ZBTB40 RPA2 PER2 ARFRP1 LY6D PEF1 RBM39 RORC HEY1 NCOA3 CST3 RPL22 TOR3A KLF15 URM1 CDHR1 DDX58 MKNK2 SGCB PUM1 LALBA ITM2B ZNF395 GABPB1 RERE EIF4G3 HSPH1 ACSL1 SERINC3 CIDEC MBP HERPUD1 UBE4B EPB41L1 CA3 ZNF770 CFB SYT13 CDC40 TOB2 FOSL2 BLNK PPM1B PPCS ITM2C RPS6KA1 PRDX6 RNF19B DHRS1 TOB1 LIN7C PKN2 MLLT3 FAM13A BSPRY ELOVL1 CHN2 PPFIBP2 AK2 FEM1C SPINT2 TSPAN7 VDR PADI2 GALNT12 PHYH GDPD3 BDH1 CPT2 SLC22A4 RSAD2	0.0584715	UP
BROWNE_HCMV_INFECTION_16HR_DN	ADH1B FILIP1L RBPMS TGFBR3 DCLK1 SLIT2 C14orf132 STMN2 ATP2B4 FBXL2 NRP1 SEMA3A CHN1 ITGAM PDLIM7 COL1A1 DIP2C ROR2 COL1A2 FGF2 MACF1 SVIL MAGI2 SERPINH1 GJA1 ADAMTS2 TUBB GDF10 KIAA0930 TPM1 COL13A1 ZFP36L2 NDP FABP3 MPG PBX1 MXD4 APOBEC3C AP4S1 CSNK1G2 WNT2 CXCL9 COG4 MVD PLEC CACNA1E TSHB LMNA SMAD6 ID2 ADH5 POLD2 FBXO21 GFAP ACADVL ANKRD1 CAMK1G DHRS3 TRAM2 RUNX1 IFT88 THBS1 UBE2C SERPINB6 PTX3 CYP3A4 METTL7A MT1H DNASE1L1 PDCD4 WNT5A NR1H3 TMEM187 RHOBTB3 ATP13A3 SEMA5A ADH1A NAAA ACAA2 ACY1 MAP2K6 SLC16A5 ANPEP AKR1C3	0.0585634	UP
VALK_AML_CLUSTER_2	GUCY1A3 CLU SCHIP1 HBB HOXB2 GRB10 MAP4K4 ARHGAP22 PTP4A3 IL2RA LPIN1 GLI2 PIM1 GOLGA8A PLA2G4A TRIM16 CCL1 JAG1 PDE3B SRSF8 DOCK1 EZR LAPTM4B HOXA5 KCNK5 PLS1	0.0587698	UP
WOTTON_RUNX_TARGETS_DN	VIP ENO2 RGS2 PRRX1 PDE8B RAMP3 ALCAM NR3C1 CEBPD MSLN SIX1 ID2 KITLG TOB2 ADD3 GAS2 ID3 FNDC3A RNF144A SGPP1 FDX1 PLOD2 XDH EGLN3	0.0588424	UP
REACTOME_TCR_SIGNALING	EVL PTPRC ENAH LCK ITK HLA-DQA1 HLA-DPA1 TRAT1 HLA-DRB5 CD4 HLA-DRB1 LCP2 CD3D CD3E HLA-DPB1 CD247 PRKCQ ZAP70 LAT PLCG1 NFKBIA FYB RIPK2 PIK3CA GRAP2 RELA MALT1 WAS IKBKB PIK3R1 IKBKG PAK2 UBE2N CSK PIK3R2 PDPK1 VASP CD3G TMEM189-UBE2V1 MAP3K7 TAB2 PTEN TRAF6 BCL10 NCK1 CHUK PIK3CB PAK1	0.0589906	UP
FINETTI_BREAST_CANCERS_KINOME_GRAY	SCYL2 NEK4 CSNK1G3 CHUK TWF1 PRPF4B MAP4K3 SLK HIPK1 TLK1 CSNK1A1 DYRK1A TRIM33 CDK17 SNRK	0.0592552	DOWN
PID_HNF3B_PATHWAY	FOXA1 BDH1 PCK1 HADH CEBPA G6PC ALAS1 HMGCS1 ACADM ALDOB CPT1A SP1 TFRC NF1 HNF1B TAT IGFBP1 ACADVL HNF1A DLK1 CREB1 CPT1B NKX2-1 TTR ALB AFP HNF4A F2 PKLR PDX1 ABCC8 AKT1 GCK APOA1 SLC2A2 FOXA2 INS CEBPB CEBPD NR3C1 UCP2 FOXF1	0.0593319	DOWN
TERAO_AOX4_TARGETS_SKIN_DN	UCHL1 SNURF IGF1 ABCD2 ACSL6 C5orf45 ESRRG FKBP15 ESF1 SCAF11 DMXL1 HIST1H1D MAU2 C17orf75 C5orf22	0.0593997	UP
BILANGES_SERUM_SENSITIVE_GENES	AKAP12 CDKN1C GABBR1 PENK JUN TUBB2A DNM1 ARL4D PSD ARID5B AQP1 BGN ZNF423 NAP1L1 KIF21B CRLF1 TUBB MDN1 MYL3 PLOD1 SUPT16H DDX6 P2RX2 XCR1 TLX2 IL3RA RRAGD GSTA4 MMP3 EIF3E POU4F1 RAVER2 UTF1 LPAR6 NSA2 TNRC6B RPL10A HIPK2 RPL31 TP53I11 NAA10 RPS18 ANKS1A TERF1 LALBA CYP17A1 CDC37 TOMM20 TLE3 SPEN HSPB11 LBR KHSRP CPT1B MTDH EIF3K IGBP1 OLA1 SLC25A17 CRYZ SIDT2 BLVRB RPH3AL CS TCF7L2 LARS2 TAPBPL AHCY ASL	0.059461	UP
KEGG_NITROGEN_METABOLISM	CTH CA2 CA4 CA12 CA1 GLUD2 CA7 GLS AMT GLUD1 CA3 CA9 HAL ASNS CA5B CPS1 GLS2 GLUL CA14 CA5A CA8 CA6	0.0595769	DOWN
REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY	AKT3 FYN LCK HLA-DQA1 MAP3K14 HLA-DPA1 ICOS HLA-DRB5 CD86 CD4 HLA-DRB1 CD3D CD3E HLA-DPB1 VAV1 CD247 PTPN6 CD28 PIK3R3 PPP2R5B LYN MAP3K8 CTLA4 PIK3CA GRAP2 TRIB3 PDCD1 AKT2 AKT1 PIK3R1 PAK2 MAPKAP1 MTOR CSK PPP2R5C CD80 ICOSLG PPP2R5D PIK3R2 PDPK1 PDCD1LG2 GRB2 PPP2CA TNFRSF14 CD3G PPP2R1A SRC MLST8 PPP2R5E RAC1 PPP2CB CDC42 PPP2R5A PPP2R1B YES1 PAK1	0.059585	UP
RIZKI_TUMOR_INVASIVENESS_3D_UP	NR4A2 TAC1 DMD TNC LHFP FILIP1L EGR2 CD69 CXCL13 CXCL12 RUNX1T1 CYP1B1 DCLK1 RYR3 FBXL2 RGS13 RHOH S1PR1 JUN PIP4K2A FGFR1 COL1A2 NPR3 PAM DUSP2 BST2 SOD3 RAB33A GLIPR1 HLA-DPA1 GATA2 SSBP2 CD72 MAGED2 SST ADRA2C C5 ARID5A FCN1 PTN ART4 ZNF32 IKZF1 PTAFR CNN2 SLC16A6 IRF5 LILRA4 CCL14 COL3A1 SEMA3F GRIK1 CCNI FAM189A2 SLC23A2 FAM50B CAMP OAZ2 CDK5R2 ABCB9 CDKL3 ZMYND10 ETV4 SLC3A2 CAPN3 SMCP DDB2 EPS15L1 GRIP1 CSF1 TAOK2 ASGR1 THPO TLX2 FGF12 HLTF CABYR SAE1 CD7 FTSJ1 NUDC RPGR GPR161 DCTN1 CASC3 MLLT10 CSE1L NR1H2 GRIN1 MMP17 MMP13 MARS POLE UBE2D4 CCK ISCU ABCB6 UBE2I TNNC1 PRR4 FAM134C SPTA1 RAB35 BRDT PTK2 PNPLA6 STOML1 SLC39A1 CTBP1 ST7 PMAIP1 DIO1 TNFRSF17 IRS2 TOP2B ZNF273 TLE1 RFX3 BCAS2 BRAF GRB2 PI4KA CYP4F8 RNF4 ZNF219 BMP6 CPA1 MT3 NAE1 TSTA3 ETV6 ZNF263 RCC1 IGF1R CCNA1 HIPK3 SLC25A6 WIF1 TMED10 UBN1 AADAC CAP1 TCF12 BCR RPS6KB1 QDPR TFAM TARDBP GTF2E2 MRPS10 ALG3 INPP1 DHX8 TYMS TCEB2 NFAT5 MMP15 AKAP5 TAP2 MAP2K4 DAO RPH3AL TIMM17A AMT STOML2 DCAF7 ATP2A2 NSDHL TBL2 UBL3 CHST5 ACYP1 VAPB RREB1 APC GZMA DNM2 MECOM SLC25A46 ALDH5A1 ADSS CNKSR1 PIK3CB LIMA1 TNFSF10 PCSK6 ECI1 SLC17A4 LLGL2 CCNA2 GNAI1 DHRS9 HMGA2 ERBB3 SRD5A1 XK	0.0603384	UP
SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN	ATF3 ATP2B4 BHLHE40 PLS3 BASP1 ACTN1 SLC7A5 BAIAP2 TRAF1 HBD TNK2 KLF9 RELA NFKB2 BTG1 DDX17 TRIOBP ETF1 EIF1 MORF4L2 HNRNPA3 CELF1 RELB CDK11A YWHAQ DNAJB6 MAEA IFNGR2 ARF6 PREP	0.0612778	UP
LUI_THYROID_CANCER_CLUSTER_1	FOSB NR4A1 MXRA7 FBN1 FYN DEGS1 BTG2 SPRY1 HHEX BEX4 ST3GAL5 CEBPD DUSP6 CCND1 CLASP1 CDC25B PLD3 SATB1 ITSN2 GOLGA8A SEPT9 PHIP CHD4 MDK ARHGAP1 GAS6 SRSF6 EPOR SMARCC1 IGSF1 CTBP2 SRSF11 MFSD10 EVPL NKX2-1 TMF1 AP1G2 SFPQ TNFRSF10B DHRS3 APLP2 LASP1 ZC3H14 HES1 ADCY9 SOX4 ATP13A3 DYNC2LI1 ANK3 LRP4	0.0612815	UP
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0	ATP1A2 GEM CFH NCAM1 ITIH5 ANGPTL2 DKK3 RPRM BNIP3 RHOQ ADRB2 SASH1 PROS1 CTSF LIFR CEBPD RTN2 SAMHD1 AOX1 RECK DBP PLA2G7 PNRC1 GABARAPL1 ENPP2 IGFBP3 GSTT2 GLRB BBS9 ALDOC VAMP4 NR1D2 DDX6 EIF4B KLHL24 CASP4 TEF ABCA1 ABCA4 PNPLA2 NR1D1 RAD51B ST6GAL1 SESN1 MAP1LC3B WDR45 BACH1 HAUS4 EPHX1 ABLIM1 NT5E CCNG2 RIN2 LOX TMEM159 MXI1 MET EPS8 HSD17B11 CPD LAMA3 ALAS1 SMPDL3A LAMB3 PROM1	0.0614914	UP
FOURNIER_ACINAR_DEVELOPMENT_LATE_UP	CRYAB SERPINA3 GPNMB TCF4 MAFB BBOX1 APOE DSG3 KRT10 SOX4 SPTSSA	0.0615164	UP
OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_DN	FLNA SERPINA3 AEBP1 MAP1A LRRC17 GLI3 SIRPB1 TRIB1 MMP2 HYAL2 NELL2 ATM AR BBS9 NHLH1 CCR9 FEV PSG11 ODF1 COL11A1 KRT6A CETN1 CCL7 CDH8 CFLAR GSTP1 SIGMAR1 TH FBN2 FUT3 LIMK2	0.0616115	UP
WANG_NEOPLASTIC_TRANSFORMATION_BY_CCND1_MYC	ATF3 IGFBP5 RGS2 ARHGAP6 EREG ARHGAP24 IGFBP4 AREG IGFBP3 COL5A3 TRIB3 DDIT3 S100G ADAM12 MMP12 CLSTN2 LPAR4 TSPAN7 TSPAN6	0.0618161	UP
CROONQUIST_IL6_DEPRIVATION_UP	ECM2 CDKN1C PDE1A ARL4C NCF2 RAPGEF3 RRAS HOMER3 LEFTY2 FCER2 IFIT1 TBC1D9 AHNAK APOL1 SLC7A7 PCDHGA8 SCGB2A2 IFIT2 FCGRT BMP2	0.0618315	UP
ZHU_SKIL_TARGETS_UP	ECM2 FN1 PPP1R15A DCN RHOQ JUNB SERPINE1 ST5 ENPP2 PLAU MMP16 HYOU1 IGFBP1 SEL1L GADD45A VEGFA EGFR CCNG2 CDKN1A ITGA2	0.0618451	UP
MARKEY_RB1_ACUTE_LOF_UP	OGN CH25H APOD PLEKHO1 MEOX2 SERPING1 BHLHE40 PRRX1 SERPINB9 CCL3 ITGAM FCGR2B ACSL4 EVI2A LMO2 CXCL2 HCLS1 ITGB2 PTPRC NPR3 CSF1R RAB8B TMEM45A IFI16 LAT2 LCP1 NCKAP1L TYROBP CD52 GATM C5AR1 NCF2 CTSH NCF4 IL7R CD72 SRGN RAC2 CCL4 CFP SAP30 STOM C1QB LST1 CRABP2 SOCS3 CCR1 LYL1 VAV1 PTPN6 FPR1 PLA2G7 C3AR1 STAB1 FCER1G TGFBI IGFBP3 LDLR SPHK1 UBE2L6 ITGAX ALDOC FAM13B IFIT1 SELPLG CSF2RA C2 GRINA ADAM8 ISG15 DDIT3 NUPR1 TNFSF9 MID1IP1 AGRN SPRR1A IL18BP GBP2 CASP4 MMP3 RAB3D DAXX SEMA7A HCK GPC4 ABCA1 GBP1 IRF7 NR1H2 HP SP100 ISG20 UBA7 DDX3Y PROCR PCSK5 PFKP CCL5 ADAR TOR3A CTSB ARNT CXCL10 IRF9 USP18 PSMB9 BNIP3L AP3S1 GGPS1 MMP10 TAPBP SGCB CCL7 KRT7 STAT1 CTSE PSME2 RBBP9 IFIT3 CTSZ TBC1D22A FAM134B IFT20 HIPK3 MBD1 CXCL14 CSNK1D GADD45A HLA-G FCGR1A IQGAP1 MT2A PCYT1A LGMN BID GRN TAP1 APP NDRG2 TOR1AIP2 ATP6V1B2 PDK1 IFI35 GLRX PFKL EDEM2 SAT1 NT5E PSMB10 RNF34 SOD2 ACP2 FNDC3A IFIH1 GABPA IFIT2 MKRN1 DHRS7 PSMB8 SKAP2 NPY LGALS3BP GBA MXI1 UBE2A FAM162A SGPL1 PLIN2 ABCG1 NDRG1 PNP GCNT2 NAMPT UCK2 ANXA4 PLAC8 SMPDL3A XDH HIST1H1C EGLN1 HIST1H2BC APOBEC1	0.061874	UP
DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN	DMD RBPMS ZEB2 NAV3 MITF HEG1 ROR1 KIAA0922 COL1A2 PTPRM MAD1L1 ARHGEF10 DOCK4 ZFHX3 CREB5 SGMS1 SLC16A7 UST AMPH CCND1 FAM168A LPAR1 AHDC1 DOCK9 ASXL1 CTIF TSC22D2 BICD1 INTS3 ABCC1 MALT1 GPR176 FAM193A ATXN1 TEAD1 DST TMCC1 KLHL20 NFIB FAM155A DNAJC2 SERPINB2 BTAF1 PEX14 SON LRP6 PCNT GPATCH8 USP15 CDC42BPA PHF14 EIF3A VPS13B PDS5B TOP1 PIK3C2A SFMBT1 HAS2 RB1CC1 SMAD7 ATRN ARAP2 WDHD1 RALGAPB WDR37 UBXN7 ACAP2 MSH3 SYNJ2 SKAP2 MPHOSPH9 HERC4 ACVR2A FAM179B TRIM24 ITCH PLCE1 GALK2 AVL9	0.0621706	UP
MOHANKUMAR_TLX1_TARGETS_DN	ASPN FGF13 BEX1 GUCY1A3 EML1 SOBP TNC APOD ANXA1 MAP1B SPOCK1 LTF RUNX1T1 SERPINA3 C1orf216 KIF5C LDB3 DKK3 CDK14 CADM1 KCND3 PDE8B SLITRK3 CD1C TYRP1 ARHGEF4 TNFRSF9 ALCAM CDH6 LRRC49 PKIA GDF15 PROS1 ST6GALNAC2 MAFB AMPH ST8SIA4 FOXN1 DUSP6 SHC2 DIRAS2 NELL2 AREG SYNDIG1 LEFTY2 BMP7 EPHA4 MAF FAM198B AAK1 DYRK4 RAB3B SGK1 CLGN S100A7 SLC43A1 NTRK1 BTC CALML5 PREX2 MFAP2 DDIT3 MCMBP ST7L FGF12 MYCN SHANK1 ZNF22 RBMXL2 PLA2G2E TXNIP KLF6 EIF4EBP1 MMP3 LRP1B ERBB4 SPATA6 CLIC3 MATN3 ASNS OR1D5 PLA2G3 SLC8A1 XCL1 NYNRIN GPR50 RASAL1 DRD2 CALCR MUC5AC CYP19A1 PTCH2 IL4R WLS RBMY1A1 SLCO2A1 AVPR1A SPINK5 NPPB GAD1 CKB PLAC1 TRIL S100P FGG UNC5B USH2A PPP1R26 RNF39 GTPBP10 MUC1 SLC2A9 HLA-F S100A6 DCAF10 BIK NMI FAM83E AUTS2 MGLL MARCKS SCUBE2 HSD17B4 AKR1C1 CEACAM6 IGSF3 GPX2 TSPO HIGD1A ABHD2 LAMC2 SEMA5A FXYD3 C3orf52 C1orf106 HPGD SERPINB5 TNIK HOXB9 LAMB3 PLD1 GPRC5A GALNT12 TFF3 CA2 MAPK13 S100A14 TOX3 IL18 PSD3 DSC2 STEAP1	0.0622423	UP
HOLLMANN_APOPTOSIS_VIA_CD40_UP	MEIS2 PEG10 MYH10 KCNN3 SYNE1 CDK14 MYBL1 RGS13 EMP3 ADAM19 STAP1 EAF2 RFTN1 DPYSL2 NQO2 USP13 TUBB2A NUDT11 BASP1 PTPRC MAGEH1 LY9 SNX10 PITX1 CREM RUNX3 LCK MAP4K4 BLK BTK CD86 DENND1C SH2B2 NRGN RAC2 NR3C1 CD22 MAP4K1 TACC1 PPP3CC TOX VAV1 PARP1 LEF1 MEF2C CHMP7 CAB39L KIAA0930 LTBP1 LRMP CYB5R1 ITGB7 GM2A PRKCA TBC1D1 PFDN2 NBEAL2 NCOR2 ARPP19 IRF8 TUBB3 FANCA PCM1 IFI30 GRK6 E2F1 PEMT TCEA1 PTPN22 CD99 TUBA1B PPP6R1 SLCO4A1 EPB41L2 DDX39A DST COPS6 XPO7 DUT PARD6A GNAS C6orf106 PEX3 GTF2F1 SBF1 PAK2 DDX3Y NFIB ZNF93 ISCU RHEB USP34 CD38 ITGB1 FNTA TUBA1C HMGB1 CYP39A1 HSPBP1 FOXN3 GTF2IRD1 ALDH4A1 FLII XRCC5 ARPC1B LGALSL DEDD TNFRSF17 TMEM147 COPS2 PDLIM2 MAK16 COPS3 SGCB ASH2L SYPL1 LSM1 CNOT7 CPNE3 RAP1B HBS1L INTS9 PLEKHF2 TRMT12 PRPSAP2 SNRPD1 SS18 HSPH1 ENSA LAP3 CLSTN1 TIMELESS BIN3 PARN PCMT1 TSFM CUX1 PPP2R2A ETS2 ADCK2 SNX19 ARPC2 SLC25A6 GTPBP6 RNF126 CAP1 CKAP4 MFHAS1 G3BP1 HDAC1 ATP6V1B2 PPP2CB MAST2 SMC4 TMEM106C MBD2 LSM4 HGSNAT MRPL34 KDM5D MRPS22 ARF3 CLTB RPS4Y1 NUSAP1 ALDH2 RNF19B CDKN3 ENDOD1 PXMP4 ATP8A1 PDGFD SRP54 MRPS33 PEX1 DEPTOR LSR SDHB MAPK6 MYO1E ACAT1 GCHFR SERINC5 AGPAT5 HMGB3 GSR SHMT1 MEST	0.0622926	UP
POS_HISTAMINE_RESPONSE_NETWORK	NNMT LOXL1 FBLN5 TGFB1 EMILIN1 JUN TIAM1 ENAH CEBPB ALPPL2 GARS ASNS CAMK2A PFN2 ADH7 CDK2AP1 NDST1 GABPB1 SLC7A1 ACPP H2AFY LMO1 ARF4 G3BP1 IGF2R IL15 TAX1BP3 GCNT1 TSPAN7 UPP1	0.0624399	UP
HILLION_HMGA1B_TARGETS	FOS TAC1 CLU EPHA3 ANXA1 CRIP2 EPHA7 SDC3 PCOLCE CXCL2 ANXA5 PNOC GFRA2 CD44 GPC1 ACHE NFKBIA TIMP2 NOS3 CCND3 LIMK1 SLC6A11 MYCN CSF2 GSTA4 GPX4 GRM5 PLAUR ACADL DCC RPL10 RPS11 RPL12 RPL19 HSP90AB1 RPL11 CD5 RPS4X HRK RPL13 RPL21 GABRR1 RPS19 MAK RPS12 GSTM2 CD80 STAT3 TNFRSF1A RPS3A CXCL10 PTMA PSMB4 VCP NME1 ID2 MIF PSMB6 CD3G UNC5B PDGFA ACADVL PCNA PSMA1 COX4I1 ARF5 PSMA6 ID1 ATP5H TK1 SOD1 AKR1A1 ID3 COX7A2 ARF6 ATP5F1 ATP5G1 CYP3A5 ATP5B FGFR4 PNLIPRP2 GMFB ALDH3A2 SLC25A5 ERBB2 COX5A NRAS	0.0628761	UP
PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP	HMMR CENPA TTF2 AURKA CDC20 RAD51AP1 FOXM1 NCK1 EZH2 NDC80 SKP2 CDC7 NCAPD2 TOPBP1 MCM4 MCM2 CDK1 TFDP1 SRSF10 SMC4 RPIA MRE11A AURKB RFC3 MSH2 PNN DEK MTF2 LBR KATNA1 DNA2 USP1 TCERG1 EXOSC8 RPA1 ASF1A SRSF11 HMGN4 RAD54L MCM6 UBE2S CEP57 MCM5 SNRPA CAD DDX39A BLM STMN1 NASP DNMT1 ILF3 MYBL2 RFC4 CDKN2C SH2D1A	0.0628904	DOWN
OSADA_ASCL1_TARGETS_UP	SCG2 ATF3 IGFBP5 ITGA1 CHGB RASGRP3 LTB RGS16 CALY CCR6 JAG2 PPP1R16B RET CBFA2T3 RASSF4 SEMA3E RAB3B RASA4 SCG3 SMYD3 ANGPT2 LFNG KLK3 SSTR1 CLDN14 MTSS1 BDKRB2 KRT14 BDKRB1 SSTR2 IGFBP1 KRT13 GAS2 SEMA6A KLK1 RHOBTB3 VDR SYTL2 MYB EDN3 RNF128	0.0629604	UP
KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM	AKR1B10 FPGT GMDS HK2 MPI FBP1 PMM1 SORD ALDOB MTMR2 PFKFB2 GMPPA ALDOA PFKL PMM2 TPI1 MTMR6 GMPPB TSTA3 PFKFB1 MTMR1 PFKP FBP2 PFKFB4 HK3 KHK HK1 ALDOC MTMR7 PFKM AKR1B1 PFKFB3	0.0632318	DOWN
ELLWOOD_MYC_TARGETS_DN	HIST1H2BC PROM1 CA2 PHYH TMPRSS2 CLDN4 TMED3 PEX2 IDE TMEM97 CHMP2A ALDH2 LAMTOR2 EGF DAZAP2 EZR ERP44 PDIA6 PTTG1IP GANAB FKBP2 UFC1 DNAJC10 CDS2 NKX3-1 MCFD2 NR1D2 SATB1 INPP5B FMOD LIMCH1	0.0635868	DOWN
CROMER_METASTASIS_UP	FERMT2 TUBB2B TSC22D3 CXCR4 COL4A1 C10orf10 SH3BP5 ARHGDIB BEX4 TMEM109 FADS1 TFAP2C ATP6V0E2 MAGED2 FADS2 SLC2A3 MFGE8 CDH11 PPT1 PARP1 SH3BGRL ENPP2 PLCG1 EID1 MDC1 BMI1 CELSR1 ATRX OR2H2 CCND3 WAS TMEM63A XPO1 REEP5 KDM5C SERINC1 MICB DYRK1A TMEM123 CNOT2 PSMB9 CTNNB1 ID2 C5orf15 PPIH SLC25A36 BUB3 CNN3 MAGED1 RPN2 DEK SMC1A GNS GPR107 NFYC TCF12 GANAB ZFC3H1 PTPRK UBXN4 CD164 SPG11 TBCE ZBED1 MFAP3 PPID PGRMC1 FCGRT CD46 MTMR2 ACVR1B SLC30A1 AGFG2 KIFAP3	0.0639024	UP
HUI_MAPK14_TARGETS_UP	SFRP1 FHL1 PRNP JUN ITGB7 JUND GRAP2 ISG15 DUSP8 GNG4 ASB1 PAK6 CNTNAP2 GADD45A GADD45G MAP2K6	0.0639101	UP
KEGG_GALACTOSE_METABOLISM	G6PC HK2 GALK2 GALE PGM1 GLB1 UGP2 MGAM PFKL B4GALT1 GLA LALBA GALT GAA PFKP HK3 LCT HK1 G6PC2 GCK B4GALT2 PFKM GALK1 AKR1B1	0.0642433	DOWN
MIDORIKAWA_AMPLIFIED_IN_LIVER_CANCER	CYR61 CAV2 CAV1 DUSP14 PLXDC1 CREM ADCY2 PIP4K2B PCGF2 SOCS7 FZD8 RPL23 MTRR WNT2 RPL19 SYNRG TADA2A PRCP PARD3 SSR1 ST7 ACACA CUL2 CACNB1 PSMB3 CWC25 HNF1B ANKRD7 DDX52 LASP1 CAPZA2 RREB1 MET FASTKD3 CFTR DSP	0.0643208	UP
KAUFFMANN_MELANOMA_RELAPSE_UP	MAD2L1 RFC5 GMNN TOP2A CHEK1 HUS1 RAD51AP1 CDC6 CENPF SMC2 RAD51 ORC4 GTF2H2 GINS2 MCM4 NEIL3 SMC4 RFC2 BRCA1 CHEK2 RPA3 TFAM CCNH PTTG1 PTTG2 SUMO1 PCNA MSH2 POLQ DEK RAD17 DCLRE1A PPIA ORC6 RRM2 MCM7 BRIP1 TDP1 TERF1 XRCC5 CDC45 CTBP2 RAD54L MCM6 FANCG EXO1 CHAF1A BLM MCM3 GTF2H3 OGG1 FANCA RFC4 XRCC2 MSH6	0.0643959	DOWN
KEGG_PENTOSE_PHOSPHATE_PATHWAY	RBKS DERA PGM1 FBP1 PGD ALDOB PRPS2 PGLS RPE TALDO1 GPI TKT ALDOA PFKL RPIA G6PD PFKP FBP2 H6PD TKTL1 PRPS1L1 ALDOC PFKM PRPS1	0.0646691	DOWN
REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION	GCHFR PRKG2 DHFR SPR GCH1 PTS CALM2 CALM3 CALM1 HSP90AA1 AKT1 NOS3	0.0649597	DOWN
HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP	ECT2 E2F8 HMMR PRC1 RFC5 CENPA KIF4A TTK NEK2 PCK2 CCNA2 CDC25C AURKA MELK HMGB3 CASP3 ACY1 CCNB1 DLGAP5 TOP2A KIF20A CDC20 CCNB2 MKI67 CKS2 IDE EDN2 GPHN ATP5D KIN HELLS CKS1B SMC2 CDKN3 PLK4 CENPE KIF23 CDKN1A RAD51 NUSAP1 TMPO DCTPP1 KIF2C RACGAP1 CIT HAUS6 KIAA0101 KIF22 HES1 PPP1CA COIL CDK1 SMC4 LDHA WDHD1 TK1 ACTN4 ABR BRCA2 GSPT1 NCAPH UBE2C AURKB CTC1 KPNA2 ENO1 RFC3 ANP32A RRM1 PSMC3 H2AFX SNX2 HSPA8 BUB1 IL4 CBX1 HTT PPIA MYEF2 POLA1 CALM2 TRIM46 RRM2 LIG1 CDCA3 PPP2CA NME2 EIF2AK2 MIS18BP1 DBF4 ARL1 CKAP5 HMGB2 PIH1D1 DNA2 CBX5 FEN1 TUBB4B CHAF1B U2AF1 FLII MCM10 RPA1 INCENP IPO5 SSX2IP CDC45 PSAT1 RAD54L STIM1 MCM6 AZIN1 UBE2S RAN VPS72 XPO1 MCM5 TUBA3C DUT RPL10 HOXC5 FAM111A STMN1 NASP TUBA1B CCNE1 TRIP13 DDX19A MMP14 DNMT1 NUDC NUCKS1 NCAPH2 ANP32B RBL1 TUBB3 AARS CAMP ZNF358 ITGB7 TUBB GSN MTHFD2 ANP32E CDKN2C HLA-DRB1 NEDD4 HLA-DQB1 NT5DC2 SLC29A1 TUBA1A RAMP1 CRIP2 MYH11	0.0651712	DOWN
PID_IL4_2PATHWAY	EGR2 CCL11 MYBL1 IRS1 BCL6 COL1A1 THY1 COL1A2 STAT5B AICDA INPP5D SELP CEBPB SPI1 SOCS3 DOK2 PTPN6 FES CCL17 FCER2 STAT5A ETS1 GTF3A IRF4 CD40LG PIK3CA ARG1 LTA IL2RG SOCS1 ALOX15 AKT1 JAK1 OPRM1 IL10 PIK3R1 JAK3 MTOR IL5 ITGB3 CBL IL4R SHC1 IRS2 STAT6 JAK2 GRB2 BCL2L1 SOCS5 IL4 RPS6KB1 HMGA1 IL13RA2 MAPK14 IL13RA1 SP1 MYB TFF3 PIGR	0.0654195	UP
KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS	CCL2 SPP1 CCR7 C3 CCL3 IL10RA ITGAM IL16 CXCL2 CCL22 LTB CCR6 CXCR5 CCR1 TNFRSF1B CCR2 CCL20 CCR4 IL6ST CD40LG CXCR2 IL1B CCR5 IL2RB LTA XCR1 IL2RG IL11 CCR9 CXCL9 CXCR3 CCL5 CXCL10 IL36RN CCL7 IL1A IFNG TNF IL13RA1 IL15 CASP1 IL6R IL1R2 IL18	0.0654245	UP
MAHAJAN_RESPONSE_TO_IL1A_DN	FOS CTGF MYH10 ZEB1 TGFBR3 F8 MITF LAMA4 PLS3 SLIT3 SLC29A1 CTNNAL1 HSD11B1 SLC2A3 IL11RA EPHA2 CHST10 CRABP2 RECK LPP EPHB4 PPT2 GRP C1orf68 CYP2A13 MAPRE2 RNF24 GSTA4 HSPA4L VCAN PEX3 UBE2N SF3B1 RPL3 LMNA PPP2R5C FOXN3 UBR5 CYP19A1 SLC25A12 DYNC1LI2 COL4A5 ARL6IP5 MAGEA11 ADH5 ASAH1 RYK GALNT2 SMC3 ACADVL POLR1C ITGB5 PCNA PTEN IDH2 TOB2 VDAC2 KDELR3 PRKCI SYNJ2 SCP2 ME1 ALDH3A2 SORD DYRK2 ALDH7A1 SRI POSTN NEK4 GALC RALA ACOX1 AKR1B10	0.0655208	UP
COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_DN	TIMP3 FN1 GPNMB SPP1 BHLHE40 DYNC1I1 PRRX1 A2M FMOD TGFBI CHI3L1 NPC2 CTNNB1 CSNK1A1 SQSTM1 COL4A3 POLR2C EDNRB PGK1 ANXA2 EGFR ZFAND6 TXNRD1 TFRC TRIM24 PLIN2 SLC30A9	0.0655273	UP
PODAR_RESPONSE_TO_ADAPHOSTIN_UP	FAM129A ATF3 CLU RGS2 ZEB1 ANXA1 CDKN1C DUSP1 TUBA1A KLF2 PPP1R15A MFAP4 JUN TUBB2A MAFF CLIC2 FYN CSGALNACT2 IL23A CREM ARID5B PALLD CLEC2B CYTIP NCF2 DDIT4 KLHL21 HSPA6 DNAJB4 RPS6KC1 CEBPB NLRP1 TRIB1 CD44 PLEK ZFP36L1 DUSP5 PNRC1 DGKG GABARAPL1 IGFBP3 BBC3 ITGAX SLC38A2 PHLDA1 HSPB1 JUND NAP1L2 NEK1 YPEL5 TRIB3 TES SLC3A2 DDIT3 TNFSF9 ATF4 ZFAND5 KLF6 ZNF165 HSPA13 MORC3 CHAC1 GARS MBNL2 MSX1 ISG20 MARS ASNS MAFG ADAM17 GOLGA2 ARMCX3 SLC7A11 PSAT1 DNAAF1 TMEM57 ASF1A WDR26 RAP2B PMAIP1 IFNGR1 NFE2L1 HIST1H2BB ID2 CLK1 CARS TMCO3 RND3 MAP1LC3B SEC24D SQSTM1 CCPG1 GLA DNAJB9 DNAJB2 BSDC1 BACH1 ZBTB43 GADD45A HDLBP VEGFA ACTR10 RB1CC1 HEXIM1 ZNF267 HBP1 DNAJB1 PRDM4 GLRX IFRD1 SAT1 CD55 FTH1 IER5 CCNG2 GAB2 FNDC3A MGAT2 STX12 SOX4 GTPBP2 NCOA2 IL15 EIF2AK3 TMEM140 ZNF215 MXI1 RAB9A P4HA2 HIST1H2AM AKR1C2 HIST1H2BG PIR HMOX1 STX3 GCLM CEBPG AKR1C3 FOXA1 STEAP1	0.0655632	UP
PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN	PEG3 NRN1 ZCCHC24 CHODL MYH11 IGF2 PPP1R3C MAP1B CDKN1C CDO1 FAT4 MYBL1 RGS5 CACNA1H MPPED2 NPR3 IFI44 RGS4 ST3GAL5 NNAT SLC27A3 CTSF TSPAN5 CADM4 TNPO2 GPC3 TPM1 SNCG PTK7 RBFOX2 SEMA3B LOXL2 ATRX DDX6 SOX2 CD14 SEC62 PTH1R HNRNPL COL2A1 PAX1 SRPK2 DPYSL4 PIK3R1 KDM5A GRPR INO80D NFIB CREBBP PFN1 TPR PCSK5 CYP39A1 GNB1 RCOR3 CBL RC3H2 SLC14A1 TINAGL1 SPTBN1 ARGLU1 ANGPT4 RGS17 ATXN2 CAP1 ANKRD11 KIAA0430 LUZP1 CUL5 NET1 IGF2R CENPE ATP1B1 PC ENDOD1 MAP3K2 WNT5A PARM1 GOLGA4 THOC2 FGFR2 HSD17B11 SLC12A2 CPD ATP9A NEO1 SELENBP1 AKAP9 PERP HMGA2 FOXA1 CLCA1	0.0655966	UP
SHIN_B_CELL_LYMPHOMA_CLUSTER_6	PTGS2 S100A8 LMO2 CDX4 IL1B WNT1 SOCS1 IFNB1 SIX3 HOXA1 ID3	0.0660151	UP
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN	E2F8 KIF15 ELOVL6 CCNA2 AURKA CDC20 MKI67 TIMM8A TTLL12 NDC80 BUB1B TMEM223 SKP2 NR2F6 ENOSF1 CDK2AP2 TMPO NIF3L1 ESPL1 NEIL3 POLR3B CCDC51 DHRS3 PRMT7 PLK1 PPIL2 XAF1 ZNF280D DDX28 ZNF93 EXOSC2 GEMIN6 FAM111A RRS1 TREX1 CCNF KIFC1 ZNF174 OSGEPL1 PLCXD1 CBX2 TACC3 ARMCX4 BARD1 LYL1 CDKN2C MCAM	0.0660574	DOWN
HINATA_NFKB_TARGETS_FIBROBLAST_UP	GREM1 CCL2 MAP1B FN1 MYBL1 G0S2 GABBR1 VIM TNFAIP2 FGF2 TNFAIP8 CD83 ICAM1 IER3 IL6 GPR37 CXCL1 CDH2 TAF15 MSC SELE TNFAIP3 CCL20 LRRN3 SERPINE1 FGF1 ETS1 NFKBIA HGFAC IL1B RELA ABCC1 EXOSC9 NFKB2 SEZ6L MMP14 OLR1 ADAMTS3 FGF5 BTN3A3 ERCC1 RPA2 RABEP1 CXCL3 MTSS1 SERPINB2 ARHGDIA MRPL33 GTF2H4 KRT7 SPTBN1 CTSE CXCL5 RELB GSTO1 RND3 MT3 HDGF GADD45A NFKB1 VEGFA CCNH AP2B1 RAC1 PTX3 IRF1 SOD1 MAPK9 BIRC2 SEC24A ARF6 EGFR SOD2 KDM6A CXCL6 CD9 LITAF GCH1 NPAS2 TBC1D12 CCNB1 MMP1 ANXA13	0.0661162	UP
CADWELL_ATG16L1_TARGETS_UP	FABP4 ADIPOQ VNN1 PTGER3 CFD LPL NPR3 SASH3 RBP4 HSPA12A PCDH17 C1QTNF1 PHF21A SOCS3 CXCL1 CD163 LEP FBXO41 PDZK1 IFIT1 CFI FUZ APOA1 SERPINA10 NPC1L1 THPO APOC2 NEUROD2 MTTP AMY1A POU4F1 CHAC1 CD36 HP HAO2 CYP2E1 CST6 CHST1 UPK1B EXOSC10 DBH SSR1 TF GZMB SLC5A12 PLEKHM1 CIDEC LHFPL2 LTK CA3 BST1 GGT1 ALPI TRIM15 KIF3B KCTD14 TMEM87A CIT SCP2 FCGRT PC FABP1 ZKSCAN1 KRT12 RSAD2	0.0661249	UP
BIOCARTA_PDGF_PATHWAY	FOS JUN STAT5B SRF PRKCB PIK3CG PLCG1 STAT5A PRKCA PIK3CA STAT4 STAT2 JAK1 PIK3R1 MAP3K1 ELK1 STAT3 HRAS MAPK8 SHC1 STAT6 RAF1 MAP2K1 STAT1 GRB2 PDGFRA PDGFA RASA1 MAPK3 MAP2K4 SOS1 CSNK2A1	0.0661574	UP
REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT	SLC22A4 SLC22A5 SLC22A18 SLC22A3 SLC22A2 SLC22A11 SLC22A1 SLC22A7 SLC22A6 SLC22A8	0.066166	DOWN
GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN	FILIP1L FRY CDK14 CCR7 PBX3 ROR1 SPOCK2 DPEP2 PNMA1 LCK VAMP1 RAPGEF3 HIVEP2 APOBEC3G INPP5F VASH1 FMOD LEF1 COL9A3 LPP FCER2 ABCA6 PTPRO CELSR1 WARS COL9A2 GBP2 PTPN22 ATXN1 CCDC88A MARS TTN MAP3K5 KCNN4 SYT17 PEBP1 C11orf80 SFMBT1 NOSIP ABR RXRA ID3 GCLC ZFP64 PDGFD DBI ALDH3A2 DNMBP IGSF3 SPATS2L AGPAT5 NEK3	0.0662372	UP
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP	TUBB2B CDKN1C DUSP1 SNN MITF KCNH2 GABBR1 MAN1C1 SASH1 MAMLD1 PIK3CD PDGFB EPHB6 MAPK8IP2 MRC2 CXCL1 HS3ST2 PHF1 SNTA1 SOX15 C3AR1 FMOD C1QL1 SPAG8 C1orf61 EPHB4 PRX PHLDA1 NTRK3 PICK1 PYGL NPPA NPEPL1 BIRC7 DDIT3 APOC2 COL11A2 POU2F2 POFUT2 GSTA4 PLXNA1 GIT1 PLAUR RPL38 AMN PTPRS TRIOBP HYI RAB11B LMNA MAP2K3 RPL37A AZGP1 SPATA2L SLC6A8 KHSRP CTRB2 PINK1 MBP PPFIA3 GNAQ B4GALT1 DAO GNA11 CTAGE9 AKR1C1 DDR1 AKAP7 MAPK1 DSP STYK1 RAB11FIP1	0.0663262	UP
BIOCARTA_GLEEVEC_PATHWAY	FOS JUN STAT5B MYC PIK3CG STAT5A PIK3CA AKT1 PIK3R1 MAP3K1 HRAS MAPK8 JAK2 RAF1 MAP2K1 STAT1 GRB2 BCR BAD MAPK3 MAP2K4 CRKL SOS1	0.0664178	UP
LIAN_LIPA_TARGETS_6M	RGS1 BEX1 GPNMB FCGR2B SLC15A3 MYO5A C1QA CXCL2 TNFAIP2 LY9 GDF15 MAFB CFP FCN1 STEAP4 C1QB CCR1 PLA2G7 CD84 C3AR1 FCER1G MMP19 FKBP5 PAPPA KIF1A MMP8 S100A9 DNMT3A CAMP CXCR2 UTRN ADAM8 SLC6A2 ACP5 MARCO FCGR2A MYRIP SEMA7A DST TLR7 IGSF6 MMP13 CD68 MSR1 CD5L SLC11A1 FABP7 MMP12 CTSB CD244 TREM2 CLEC4E SNX6 LIPF NEU1 HMOX1 GALC IL1R2 CLCA1 APOBEC1	0.0666085	UP
LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT	TMOD3 DSC2 RARRES1 ERBB3 GDPD3 ANXA3 EMP1 CLDN7 RAB11FIP1 GPRC5A CEACAM1 APOBEC3A SYTL2 TUFT1 MYO6 SLC17A5 GCNT3 INPP4B TRIM2 SLC20A1 MALL CAMK2N1 MXD1 SOX9 CEACAM6 SAMD9 MYH14 ELF3 LCN2 VSIG10 B4GALT4 SLC12A6 KRT13 EPB41L1 NEBL PINK1 S100P PI3 VGLL1 KRT7 VTCN1 EPS8L1 DKK1 AZGP1 SCEL KRT4 ENC1 PDK4 IKZF2 SLC6A14 MUC16 GABRP IL1RN CST6 STS CRIM1 CRCT1 CLIC3 IVL KRT23 KLK6 SPRR3 SPRR1A SH3TC2 KRT81 TLR1 PSCA FYB FUT1 FAM63B SLCO3A1 CYP4B1 ADAMTS9 DUSP5 DAPP1 TACC1 ALDH1A3 KLK10 DAPK1 ARHGDIB PLA2G16 RHBDL2 EGR3 CTGF PTGS2	0.0670617	DOWN
REACTOME_RAF_MAP_KINASE_CASCADE	NRAS MAPK1 KRAS CDK1 MAPK3 MAP2K2 YWHAB MAP2K1 RAF1 HRAS	0.067103	DOWN
CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP	BSG TJP3 SPINT1 NEU1 POR KCTD5 DDR1 CLDN3 PRKCD SYNJ2BP SLC37A1 TOLLIP ARHGEF16 CORO1B CYB561 LASP1 MMP15 BIK CDK16 BRMS1 TMED10 RNF126 HNRNPAB CDC34 PMPCA ADIPOR1 CLSTN1 NEDD8 MVK GPX4 UBE2M AKT1 DUSP10	0.0675285	DOWN
ONO_FOXP3_TARGETS_DN	P2RY14 TGFBR3 CXCR4 SELL RUNX3 GPR171 IGFBP4 BCL2 CD84 PARP1 CDK6 RUNX2 TNFSF8 IRF4 SEMA4A TCF3 CXCR6 RBL1 E2F1 CASP4 CCNF FASLG IL21 TNFRSF25 IL17A FFAR2 HNRNPA1 CCL5 RBL2 FOXN3 IL4R IL17RA IL4 CDKN1A GZMA CASP1 CCNA2	0.0675289	UP
HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_DN	CYR61 EGR1 TGFBR3 ITGB2 SPRY1 NCS1 EGFL7 A2M TNNI3K ZNF232 VCAN TAT MST1R SCD FXYD3 CDH1 GALNT3	0.0675954	UP
KATSANOU_ELAVL1_TARGETS_DN	TGFBR3 CXCR4 THBS4 GRB14 ANGPTL2 KIF5C STMN2 DUSP10 AEBP1 TIAM1 SGCD COL6A2 NMNAT2 FOXF2 TMEM45A IFI16 LAMA2 RAMP3 PITX1 OSMR FAM131B PLXNC1 COL6A1 COCH CDR2L HOXD13 INHBB FHL3 ST3GAL6 PPBP CLIP4 FLT4 CD44 FGL2 ADAMTS9 IGFBP4 TGFBI TNPO2 C17orf53 SGK1 COL5A3 CDH3 TBX4 EDIL3 MYBL2 DAAM1 FOSL1 ROGDI ETV4 FANCA FST HOXD11 TCOF1 HAUS7 FUS TNN EML3 ARMC6 GJB3 KLHDC8A WNT2 TFAP4 NOLC1 PKMYT1 RRP12 PFAS IL1RL1 INCENP SERPINB2 FPGS SSR1 TROAP LIG3 SLCO2A1 DDX23 AVPR1A DKC1 PRG4 GSTM1 PDGFRA MNS1 PWP2 TIMELESS ETS2 MPHOSPH6 MED18 CHD1L UBE2C PUS7L RINT1 METTL13 PUS7 NEDD4L TEP1 CXCL6 SLC19A1 MGLL DLST STK38 DEPDC1 KIF18B FBN2 DHFR EPS8 PDE8A ANK3 ALDH7A1 PAK1 ARNTL SHMT1 IQGAP2 HMGN5 STEAP1	0.0678753	UP
ASTIER_INTEGRIN_SIGNALING	FOS FERMT2 RASSF2 USP13 CORO1A CD79A SPRY1 GATA2 ZYX DLGAP4 GFRA2 KIF21B GDPD5 MDN1 ACACB JUND LYPD1 ETV4 HHLA1 DPF2 STARD3 RRAGD GJB3 ODF1 ABCA4 SBF1 GPX1 MTOR PSMC1 CCT4 CHRNB4 GAA SFTPD VAV2 IK KRT4 N4BP2L2 VPS45 ITGAE NUP205 EIF2S1 SQSTM1 TOR1A NUP88 ZBTB7A NEMF EPB41L1 U2AF2 COPS5 ACSL3 PIK3C3 MLXIP LGALS8 TMEM131 LIMK2 CASP7	0.0685714	UP
LINDSTEDT_DENDRITIC_CELL_MATURATION_A	RTN1 CCL2 TNC CCL3 ENTPD1 CD48 CXCL2 KYNU CREM IL7R ICAM1 SLC7A5 IL6 CCL4 GPR137B CXCL1 CD44 PLEK CD40 HCAR3 CCL20 PLA2G7 INHBA TFEC FKBP5 IL1B ISG15 SLC3A2 PLA2G4A TNFSF9 MALT1 STAT4 CSF2 NFKBIE TLR2 PLAUR TNFRSF4 ATF5 GBP1 IL1RN IL12B SLC7A11 TRIM16 PTGER4 CCL5 CCL1 CXCL10 SCARF1 CCL8 STAT1 PLAT RAB5A TNF PSMA3 CXCL11 MAN1A1 SOD2 NFE2L3 CD58 IFIT2 TXNRD1 ACVR2A ATP13A3 P2RX4 IL7 CCL15	0.0691204	UP
BIOCARTA_TOB1_PATHWAY	TGFBR3 TGFB1 TGFB3 CD3D CD3E TGFBR2 CD247 CD28 IL2RA TGFB2 TGFBR1 IL2 CD3G IL4 SMAD3 IFNG TOB2 TOB1 SMAD4	0.0691212	UP
WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_DN	ANXA1 MAL GPX3 OBSL1 CSTA RELN ARL4D PPL CBR3 CRABP2 VAT1 ST3GAL4 SLURP1 ECM1 NFRKB RARG SULT2B1 LGALS7 TRIM29 KRT1 SERPINB3 MAFG KRT6A TPD52L2 KRT4 PAX9 S100A2 LY6G6C ALOX12 FDXR CSTB NEDD9 PGD CDA EMP1	0.0691463	UP
REACTOME_XENOBIOTICS	CYP2B6 CYP2C18 CYP2C9 CYP3A5 CYP2D6 CYP3A4 CYP3A7 CYP2C8 CYP2F1 CYP2C19 CYP2E1 CYP2A6 CYP1A2 CYP1A1 CYP2A13	0.0693239	DOWN
IVANOV_MUTATED_IN_COLON_CANCER	ESRP1 HMMR CTNND1 RNF43 MARCKS MSH3 NCOR1 LTN1 PHF14 B2M BAG6 MAP1S FXR1	0.0693528	DOWN
LEE_LIVER_CANCER_SURVIVAL_UP	EHHADH UGT2B15 UGT1A6 AMACR CPT2 SRD5A1 OTC CYP4F11 BDH1 CRYL1 CYP2J2 PCK1 IL6R PCCB GJB1 G6PC RUNDC3B SELENBP1 ACADS TTPA ALAS1 HGD SLC22A18 CDHR5 SLC35D1 DCXR PHLPP1 PCSK6 CES3 CES2 NDUFS2 IVD ECHS1 C1orf115 SGPL1 ALDH1L1 AGL MSRA TACO1 RDH5 PC TSKU PRDX6 NF1 SLC25A10 CYP2D6 ABCG5 C4BPB AMT SALL1 ZBED1 INSR TMEM176B MRPL46 F12 PCYT2 CYP3A4 UGT2B4 AMFR NDRG2 KNG1 DSG1 ABHD6 DENND5B EPHX1 AQP9 PINK1 ANXA9 CRAT ACOX2 HAGH COBLL1 ACSL1 SERPINC1 HSD17B10 SERPIND1 DPYS SPINK2 MRM1 UNKL ECHDC2 FAM169A DIO1 PAH CPB2 ATG16L1 ALDH4A1 CGREF1 FAM134C MTSS1 MST1 SULT2A1 EGLN2 PKLR FBXO31 NECAB2 C6orf106 CFHR5 MVK GLYAT RHBG F13B BAAT KHK INSIG1 APOC3 ZBTB22 HPD MYRIP KLK3 CCL16 CUX2 ABCC2 MORN1 APCS VPREB1 SEC14L2 FMO3 ACSL6 HYAL1 SLC6A12 MASP2 SLC38A3 ASGR1 HAO1 CPN2 C2 SLC2A2 SEPT4 ITIH1 ITPR2 CABIN1 WNT11 AR SLC27A5 ABCA6 MLXIPL LPIN1 STK32B OGDHL PIPOX AOX1 ACSM5 MAP4K1 ZBTB20 F10 RGN SERPINF1 CDO1 CAND2 MPDZ SERPING1 CES1 HSD17B6	0.069398	DOWN
REACTOME_KINESINS	KIF15 KIFAP3 KIF4A KIF11 KIF20A KIF23 KIF2C RACGAP1 KIF22 KIF3B KIF18A KIF2A KIF5A KIF5B KIFC1 KLC2 KIF3C KLC1	0.0695549	DOWN
WHITEFORD_PEDIATRIC_CANCER_MARKERS	PBK GGH MAD2L1 PRC1 CENPA TTK NEK2 KIF11 CCNA2 AURKA MELK HMGB3 CCNB1 DLGAP5 TOP2A ZWINT CCNB2 HN1 MKI67 DHFR TPX2 CKS2 CENPF CKS1B PLK4 CENPE SOX4 NUSAP1 CENPN TMPO RNASEH2A ESPL1 ASF1B GINS2 MCM4 CDCA8 CDK1 SMC4 TYMS WHSC1 SLC25A40 TK1 KIF14 BIRC5 NCAPH UBE2C POLE2 PTTG1 KPNA2 ENO1 ILF2 RFC3 PCNA GAPDH PON3 CKAP2 H2AFX POLQ BUB1 HIST1H4C LMNB2 ZMYM2 PAFAH1B3 RRM2 MCM7 DBF4 DTYMK NME1 ATAD2 EIF4A1 CDC45 MFN2 PSAT1 RRP1 MCM5 SNRNP200 BCAT1 STMN1 RECQL4 NASP CDK4 EIF4EBP1 DNMT1 E2F1 GABRB2 MYCN CCNT1 NUDT1 KLKB1 ILF3 CDC25A ADCY3 ODC1 MYBL2 RFC4 CDK6 TWIST1 TMEFF1 GPX7 TUBA1A MLLT11	0.0699092	DOWN
WANG_METASTASIS_OF_BREAST_CANCER	BCL2L14 ACOT11 FUT3 TNFSF10 PARP4 GAS2 MYH2 RPS4X CEP57 ZNF362 GABRQ COL2A1 RFX7	0.0703229	DOWN
REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE	RHOB AKT3 COL1A1 FYN COL1A2 LCK RAC2 LCP2 PLCG2 PIK3CG VAV1 FCER1G LAT PIK3R3 LYN PIK3CA AKT2 RHOG AKT1 PIK3R1 PIK3R5 PIK3R2 PDPK1 RHOA SYK RAC1 CDC42 PRKCZ PIK3CB VAV3	0.0704389	UP
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5	BEX1 ATF3 GAP43 COL5A2 COL15A1 RELN BASP1 PER1 CX3CL1 IER3 KLF10 IL18R1 ISG20 CYP2E1 S100G HSPA1A VEGFA ADM KCNQ1 NDUFB2 KLF4 CNDP2 LCN2 USP2 WWC1 XDH PCK1	0.0706212	UP
KOBAYASHI_EGFR_SIGNALING_6HR_DN	CYR61 G0S2 JUN MAFF CX3CL1 IER3 EPHA2 DUSP6 CCND1 DUSP4 DUSP5 FOSL1 IL11 VEGFA PHLDA2 F3 HMGA2 TGFA	0.0706925	UP
GNATENKO_PLATELET_SIGNATURE	CLU FLNA F13A1 HBB RGS10 SPARC TLN1 NRGN PPBP HBZ ITGA2B RNF24 CD99 GNAS GPX1 ACTB CCL5 TOP3B PTMA UBC MYL6 TUBA4A RPL41 HIST2H2BE ITM2B B2M OAZ1 TMSB4X TAGLN2 HLA-E DYNLL1 H3F3A HLA-C GAPDH CFL1 YWHAH PF4 HIST2H2AA3 NCOA4 MYL12A MLH3 HIST1H2BM FTH1 PGRMC1 HIST1H2AC	0.0707335	UP
REACTOME_ACTIVATION_OF_GENES_BY_ATF4	ATF3 CCL2 NFYB DDIT3 EXOSC9 EXOSC7 EXOSC1 ATF4 EXOSC2 ASNS EXOSC8 DCP2 ATF6 NFYA KHSRP EXOSC4 EXOSC5 PARN HERPUD1 IGFBP1 DIS3	0.0710025	UP
STREICHER_LSM1_TARGETS_UP	FGF13 CXCR4 ITPKB FZD7 BCL6 TCEAL1 MYLK GATA3 GATA2 PDGFB PAK3 INHBB IL6 NR2F2 SATB1 HSPB1 DAAM1 CDC25A PBX1 RBL1 STAT2 MAP3K1 SOX13 ST13 CDC45 FOXN3 ARNT ARID4A IL15RA CLOCK CITED2 POU2F3 KDM5B SOX4 IL13RA1 CDC6 ELF3 FGFR2 TNFSF10 ZKSCAN1 NR3C2 INPP4B PLCB4	0.0711027	UP
KEGG_HEMATOPOIETIC_CELL_LINEAGE	CR2 CD37 ITGA5 MS4A1 ITGA1 CD1C ITGAM CD19 CSF1R ITGA4 HLA-DRA CD2 IL7R HLA-DRB5 CD4 CD34 IL6 CD22 HLA-DRB1 IL11RA CD3D CD3E HLA-DRB4 CD44 GP1BB CR1 MME IL2RA GP1BA FCER2 EPO CD8A FLT3 KIT CSF3R FLT3LG CSF3 IL9R CSF2RA IL3 IL1B ITGA2B CD1D CD1B CD14 CD33 CSF1 THPO IL3RA CD1E IL11 GP9 CSF2 CD8B CD7 TPO CD1A CD36 EPOR GYPA CD5 CD38 IL1R1 DNTT IL5 ITGB3 IL5RA IL4R GP5 KITLG CD3G ITGA3 IL1A IL4 CD59 FCGR1A TNF CD55 CD9 TFRC ITGA6 ITGA2 IL6R IL1R2 IL7 ANPEP	0.0712287	UP
NIELSEN_SYNOVIAL_SARCOMA_DN	C7 IL16 ITGB2 RNASE6 ARHGDIB UCP2 HLA-DMA CD4 CYBB AIF1 NUPR1 RARRES3 MYOF TRIM38 IFI35 CASP1 CTSS LGALS9 SQRDL	0.0718112	UP
ASTON_MAJOR_DEPRESSIVE_DISORDER_DN	CDH19 CRYAB PLP1 CAP2 NFASC APOD SPOCK1 CDKN1C SORBS2 PMP22 PCSK2 MAL LDB3 RDX JAM3 GPRC5B TIAM1 PLLP EVI2A MAPT COL16A1 APLP1 ARHGEF10 ABCA8 ASPA HSPA2 EFS FADS1 GPR37 LMO4 CRYBG3 CNTN2 LPAR1 BBX CADM4 ATM PRKCQ SRPK3 BIN1 LILRA4 DIMT1 ENPP2 LIPE MDC1 NTRK2 AAK1 MOBP LRP8 TMC6 SLC4A2 RNASE1 FOLH1 CACNG3 MX1 ZFP36L2 EPHA5 CAPN3 ARHGEF2 SPOCK3 MYO9B SOX10 LIPA BRD2 MAG GABRB2 STIP1 DFFA CLDND1 KLK6 PIK3R1 TMEM63A EEF1E1 WWP1 BCAT1 OLIG2 UNC13A ABCA2 RASGRF1 SF1 CNP PRPF19 GOLGA2 DICER1 PTK2B P2RX7 CYP19A1 MAPK8 DDX11 DYNC1LI2 PCBP2 COL4A5 TF SNRPE PDE6B HTR4 FAM53B TSPYL1 MCM7 SYNGR2 MOG CDC42EP1 VAMP3 SS18 NUP88 RBM8A DPH2 GLA NPC1 PTP4A2 ST18 SNX19 TRIO FRMD4B EP300 CDK18 TAF11 NKX2-2 PSMD11 SRSF10 AMD1 SCAMP5 TMBIM6 COPA TMEM87A SEMA3C NAPA ADIPOR2 PPP2R3A PROSC SYNJ2 RNF19B PDK2 ENOSF1 UBE2A LITAF SLC31A2 PLAGL2 KIF13B MTMR2 CDK8 FGFR2 PPFIBP2 PSEN1 SCARB2 MAN2A1 PDE8A MYO1E ZKSCAN1 KIF1B LAMP2 RALA ERBB3 UGT8	0.0718594	UP
HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_DN	EGR1 CD69 HSPA2 ITM2A LUM LCP2 A2M FBXO11 PABPC4 IRF8 TAS2R14 KCNK2 IL1RL1 HSPA1L PARD3 IL1RAP PDGFRA HSPA8 CRYM WNT5A CDH1	0.0719048	UP
JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN	C7 TIMP3 THBS4 THSD7A DPP6 EMP3 FSTL1 ELK3 COL6A3 VEGFB AQP1 F10 IL6 A2M CDH11 HSPG2 ERCC2 FES NPR1 PYGL IFNAR2 SPIN2A CUL1 CSF1 GMPS IL11 MYL4 ABCC2 ELANE CDK4 NCL TXK CYP4A11 HMGB1 NF2 GAA THRA GRM3 STAT6 TUBA4A CD300C EIF4G2 AFF1 NUCB1 USP7 MPP3 IRF2 PRKAR2A ALDH1A1 CAPN7 SULT1E1 PFKL ALAD ACP2 CKS1B RNF141 NAMPT CLCN3 G6PC ATP7B ADH6	0.0719174	UP
VALK_AML_CLUSTER_12	FGF13 STXBP1 MXRA7 PTGDS NKX3-2 LAMC1 MFNG PTGER1 GABRE HGF VCL CST7 PRODH NAALADL1 AFF2 PCBP3 MST1 SIX3 PTCH1 RAB5B ARHGAP4 CALR P4HB AZI2 NRIP1 TMEM87A SKAP2 LGALS9 GALNT3	0.071941	UP
MURAKAMI_UV_RESPONSE_1HR_DN	EGR1 IL6 NINJ1 ITGB7 ACAN ROCK1 TNR SMO VTN CYTH2	0.0719733	UP
LEE_LIVER_CANCER_MYC_E2F1_UP	FABP4 PALMD BCL2A1 LPL SPP1 PTGDS COL1A1 COL1A2 SPARC LY6E IFI44 ANXA5 HLA-DQA1 LAMA5 PPL CD72 ICAM1 CD74 GPC3 NUCB2 SLC13A3 UAP1L1 FMO3 ROCK1 SPTAN1 SLC1A4 CXCL9 RAD51B LY6D TPR CYP39A1 MMP12 USP18 CISH ACTG1 CD63 TAGLN2 IGFBP1 PLAT SMC4 CDK1 TMEM176B ANXA2 IFIT2 NUSAP1 PLSCR1 UNC13B LCN2 CSTB CTSS KIF20A KRT8 MAD2L1 SPINK1 VIL1 DEFB1	0.0722006	UP
KANG_IMMORTALIZED_BY_TERT_UP	ACTG2 NNMT TNC LEPR PCDH7 C3 ELN TGFB1 BNIP3 VCAM1 IL21R CHRNA3 COL6A2 CSPG4 FGF2 DOCK2 CABP1 TRPV2 BGN ST3GAL5 PDGFB ICAM1 CDC42EP3 NTF3 TNFRSF6B PDGFC GPR162 CACNA2D1 COL7A1 LEFTY2 BDNF SCN11A TGFB2 IAPP SLC6A6 IFI30 HPCAL1 P2RX3 HPD CD36 TFAP2A RHEB MAPK4 RPS19 LAMB1 SERPINB2 ZNF460 GRIA3 CDK10 DKK1 NRCAM COL8A1 INSL4 DHX9 PCDHB8 ITGA3 CTSZ NSMAF AP4E1 BCL2L1 APPBP2 ZNF45 SLC29A2 DOT1L CDK13 ENO1 COL4A6 MAPK9 CLN8 LARS2 RPS4Y1 TNFRSF11B SKAP2 CKS1B STXBP2 WNT5A PPP1R3D CDK7 P4HA2 SPHAR LAMC2 TJP3 POSTN CENPA RARRES1 CLMN ACE2 PPARG	0.0723737	UP
BROCKE_APOPTOSIS_REVERSED_BY_IL6	CCL2 CAV2 MAP1B CXCR4 AP1S2 HBEGF SPP1 ATP2B4 BHLHE40 HEG1 BCL6 JUN MYLK MAFF CHST15 JUNB C10orf10 ZFP36 EVI2A POU2AF1 EVI2B GATM RGS16 CD180 DAPK1 ICAM1 IER2 SLC2A3 ST3GAL6 CEBPB SOCS3 CD44 SLA DUSP5 DOHH SH2D2A SLC16A6 PTP4A3 IL6ST LDLR PIM1 LTBP1 DYRK3 LRMP PRDM1 IRF4 SGK1 CDK17 TMEM184B PIM2 MAP3K8 DUSP3 MX1 HHLA1 ZFP36L2 TPM4 ANAPC10 SOX2 SBNO2 ARFGAP3 MAPKAPK2 SOCS1 PTPN11 ELL2 POU2F2 MCL1 FAM3C POLR3F CD8B RAPGEF4 SRPK2 HSPA13 EEF1E1 HCK CADPS EPB41L2 GAS6 PNO1 FLOT1 ZBTB11 SF1 PHTF2 GADD45B HNRNPU MAZ STAT3 FOXO3 IRF9 IFNGR1 BCL3 RB1 STAT1 GRB2 TMF1 RNF13 PDGFRA RAD1 HSPA1A DNAJB9 PAN2 ACPP GADD45A NCBP2 MUC1 BCL2L11 DPM1 STK17B ID1 RCN2 IRF1 SREK1IP1 MT1X MT1H NMI ID3 EIF5 PTPRG TGIF1 AMPD1 PTP4A1 CCNC DNAJA2 ADIPOR2 MARCKS EIF4E PLSCR1 TMED7 TXNDC9 MSMO1 LITAF TWF1 RHOBTB3 PLEKHB2 TNFSF10 LPCAT4 NAMPT VWA5A RALA WIPI1 GNA13 OAS1	0.0723841	UP
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6	CTGF ADIPOQ CLU CXCR4 CRIP2 LTF CDKN1C CFD LPL EFHD1 C3 PRNP ARHGEF3 PAM ARL4C DDIT4 CLDN5 ADRA2C GHR LIPE ZFP36L2 GLTSCR2 NUPR1 RETN BTG1 USE1 MAP3K1 TEC SP4 CDH16 WLS ID2 TACSTD2 IFIT3 IGBP1 PRSS23 MED24 CA3 SDC4 ITGB4 TMEM106C PPP2R5A CAPG CD55 TGIF1 BLNK CDC23 IFIH1 IFIT2 EFNB2 ME1 F3 EFNA1 ABCB1 EPCAM KRT18 DSP PERP CRYL1 HMGA2 TMEM30B PTPRR PKP2	0.0724252	UP
ROPERO_HDAC2_TARGETS	RBPMS AP1S2 STMN2 TNXB EMP3 SEPT6 PLA2G5 CCDC85B ASAP1 IGFBP7 TNFAIP2 APLP1 CORO2B MACF1 KCNK3 ZSCAN18 SLFN12 TM6SF1 EPHA2 INS PDE4D PBX2 FGF14 PTHLH ST3GAL1 SERGEF ACHE SNAPC1 DGCR6L RBFOX2 NPY2R METTL10 STEAP1B APOL2 SLC6A2 EEF1D KLK13 B4GALT6 BIRC7 COMP C11orf68 TLR6 GP2 SLC22A6 MAG TXNIP MORN1 EIF4EBP1 TBX2 HSPA13 PCDHGA9 SHARPIN DLEC1 GNLY PDX1 PPOX UBQLN3 TMEM209 MMP16 CEP57 BAHCC1 GIP TXNRD2 ADCY10 TADA2A DOPEY1 CKMT2 SMAD6 SPTBN2 MDM2 GZMB AQP4 FANCE BNIP3L FUT5 ZCCHC4 CDC42BPA MOG CORO1C RABEPK FCAR TSTA3 FIBP RAD52 SEL1L APOA2 KCNJ6 RUNX1 NCOA4 ADD3 NADK CYP2D6 WNT6 HAPLN1 CHIC2 GSS PPP2R1B UCHL3 CCDC88C NEK3	0.0728388	UP
FIGUEROA_AML_METHYLATION_CLUSTER_4_DN	CSGALNACT1 CCR7 EPHA2 IL2RA PTPRS CEP350 GBX2 MED25 CTDP1 TACR3	0.0728589	UP
MASSARWEH_TAMOXIFEN_RESISTANCE_DN	SYT1 MGP CALB2 TUBB2B AMIGO2 TUBB6 EGR3 DLC1 AP1S2 CXCL12 MYBL1 BLVRA ATP2B4 ANXA6 IRS1 CADM1 RAB31 WASF1 ELOVL5 OLFM1 TIAM1 CPE MPPED2 SH3BP5 MAPT SCD5 SH3BGR ATRNL1 DUSP2 CRABP1 TPD52L1 TFAP2C NAB2 ZHX2 ARL3 SEMA4C APBB2 ST8SIA4 FADS3 TSPYL2 STC1 SUPT3H CD44 CELSR2 COL5A1 RHBDF2 IL27RA MAP2 SERPINA5 IGFBP4 BCL2 AREG SLC39A6 LRIG1 MYO16 KLF10 FKBP5 PNPLA3 TNNT1 RAB11FIP3 FAM89B PDZK1 HIP1 GFRA1 DSCAM CBX2 S100A7 PIKFYVE MEGF9 ATP11A STARD13 ETNK2 IRX5 EFNB3 HCFC1 KAZN DARS FZD1 HPCAL1 PIK3R1 MAP3K12 RHOBTB1 SLC1A4 TEAD1 SYT12 SUSD4 KCNJ3 LAGE3 TCN1 IGSF1 HOXC10 CDV3 FRAS1 E2F4 PGR NSUN5 RNF167 ESR1 NBPF1 KDM4B PARD6B TMPRSS3 MYOF COL4A5 FOXO3 PMAIP1 TIPARP GREB1 NRCAM CBX5 ELOVL2 MOCS2 HNRNPA0 PRLR SOX3 CISH PLAC1 DLG5 NPY5R POLR1D GLA CUX1 IGF1R PRSS23 ADCK2 CCNA1 SYBU THSD4 GPR173 MT2A TPBG SIAH2 CCNG1 AMFR SCARB1 RXRA ADD3 NRIP1 PTPRG MBOAT7 CTPS2 ISOC1 ADCY9 PSMG1 PDCD4 NPY1R PDLIM1 HR SOX4 LMNB1 TSKU FLNB APTX RHOBTB3 RBBP8 DEPTOR PARP4 TMEM164 DDAH1 CA12 TMCO6 SRI TOP2A GCHFR PYCARD SLC26A2 HPGD CCNB1 SGK3 HNMT LAMP2 IL17RB ADRA2A TST ZBTB10 MREG SMPDL3B ABAT TMPRSS4 MYB SLC22A5 TTC39A FRK	0.0728952	UP
REACTOME_INTRINSIC_PATHWAY	SERPING1 F8 VWF F10 A2M GP1BB GP1BA KLKB1 GP9 F11 PRCP F2 GP5 F9 KNG1 F12 C1QBP	0.0729004	UP
SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN	FOXA1 PSD3 KIAA1324 SLC27A2 SLC44A4 TOX3 ERBB3 AGR2 TFF3 VAV3 CDS1 RBM47 SELENBP1 TJP3 DACH1 CLCN3 MCCC2 CA12 IVD DEPTOR MLPH CYP2D6 ZNF91 SLC9A1 INPP5J CRIP1 SIDT1 NRIP1 PGRMC2 BIK DCAF10 QDPR JMJD7 TSFM ASAH1 LIN7A SLC7A8 RAB27B SPDEF GREB1 N4BP2L2 COL4A5 KDM4B DNAJC12 ESR1 ZNF446 CCNO GALNT6 MAP9 ERBB4 IKBKB IL11 GSTM3 MAST4 SLC4A8 TBC1D9 NPDC1 DNALI1 CELSR1 CLGN AR TTC9 IL6ST CXXC4 CYP4B1 STK32B ASTN2 SERPINA5 CHST8 SLC19A2 RET ST6GALNAC2 GATA3 MAPKBP1 ALCAM MAPT EVL ITPR1	0.0733548	DOWN
PID_PTP1B_PATHWAY	CAV1 LEPR IRS1 FYN CSF1R STAT5B LCK PDGFRB BLK PDGFB SOCS3 FGR CDH2 INS LEP LAT STAT5A LYN PIK3CA ITGA2B CSF1 FCGR2A AKT1 TRPV6 DOK1 PIK3R1 FER HCK SPRY2 CSN2 NOX4 TYK2 CSK PTPN1 ITGB3 YBX1 STAT3 SHC1 PRL JAK2 PRLR GRB2 RHOA SRC INSR EGF EGFR CRK CAPN1 YES1 TXN	0.0733844	UP
FALVELLA_SMOKERS_WITH_LUNG_CANCER	ADAMTS1 ANK2 NFASC MYH11 RHOB NR4A3 DUSP1 BTG2 C1S ENG STC1 CCL20 SERPINE1 HOXC8 FKBP5 IL6ST HAS1 SUPT16H FOLH1 ZFP36L2 PRKG1 SRSF5 MAPKAPK2 MCL1 AGTR2 FUS CYP1A1 CYTH1 MICALL2 CRTC1 FER OTUD4 MATR3 TAOK1 MVD HSP90AB1 MAT2A EIF1 SERPINB2 TTC3 AZGP1 AQP4 DDX3X SCAF11 EPAS1 PGS1 FGG SEC61A1 RNF125 TOP1 ACTR2 IQGAP1 WDR1 HSPD1 UFM1 EZR USP10 CXorf56 SOD2 CAMKK2 RCAN1 CTNNA1 MET NAMPT APOL6 ITGB6	0.0734406	UP
PODAR_RESPONSE_TO_ADAPHOSTIN_DN	SDC1 HK2 C1orf106 SCD TFRC MSMO1 IDI1 UNG FDFT1 DHCR7 ACTG1 CXCL10 INSIG1 CCNE1 CCNF RRP1B GLI2 CX3CR1	0.0735056	DOWN
BORCZUK_MALIGNANT_MESOTHELIOMA_DN	LMOD1 C7 CCL2 APOD CCL21 FXYD1 THSD7A MS4A1 HEG1 CD79B LCAT CD19 PTPRCAP CD79A RGS16 PNOC IL7R RAPGEF3 CD22 CFP DENND3 AOX1 TRAF3IP3 ACAP1 FCER2 CD6 C6 SEMA3F DISC1 MYL3 SEMA3B TRAF1 TCIRG1 NBEAL2 CPA3 GRAP2 TNPO1 PRB1 RDH16 CAPN3 NKTR MAST4 VIPR2 NECAB3 NCR1 FGF12 SEZ6L ARAP1 CDKN2A RBBP6 CHRD LBX1 CLCN1 STS SF1 FSCN2 ATP2A1 CD38 CKMT2 RCE1 N4BP2L2 ERCC5 RAD9A NCK2 HEXA ANXA9 PLA2G2A OVOL3 PLXNB1 C11orf80 ACSM1 ZBTB7A POP5 FKBP2 SFPQ B4GALT1 HAS2 HEXIM1 FRZB ATG2A CASP10 TAP2 SAT1 PCSK7 AMPD1 CTTN XPNPEP2 CYP3A5 TRAPPC10 DDT VILL AGFG2 ARHGAP44 HSPA1B	0.0735637	UP
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN	TAC1 ACTG2 CALB2 LOXL1 SORBS2 ISLR SPEG KCNH2 IRS1 WIPF1 FBN1 TCF21 PCOLCE FYN SGCA CD79A PCDHGC3 ACTN1 MAD1L1 CRABP1 NRTN MAPK10 BLK IER3 CTF1 CEBPB PBX2 SEPT5 IDS GP1BB AMH INSL3 ADRA1B MAP4K2 MYOG HOXA4 GAMT BMP7 ASMTL PFKM FOXJ1 CDX4 ATP1A3 CHRNB3 LRMP CA6 KRT31 NPBWR2 ITIH1 ATXN2L DNASE1L2 APC2 APLNR BAIAP2 TRAF1 BICD1 CKM SHOX ARTN MYOD1 INPPL1 BRF1 COL9A1 RAD23A HCFC1 COX6A2 AKT2 MYBPH KRT17 NPAS1 BAIAP3 CHRM4 GABRA6 ZBTB17 MDK ALOX15B PRM2 IKBKG LMX1B INSIG1 MGAT3 GPR25 GHSR ADCYAP1 GTF2F1 MVD VGF PPM1G RGR CD68 MSR1 SHMT2 ATP4B CHRNG PFN1 GOLGA2 SLC30A3 DVL1 TUBG1 DHX16 CYP19A1 CRYBB1 HMGN2 SRP14 GPR32 OMP RAD9A MAT1A PRL SRY KIF5A CST5 TLE3 CD151 ITGA3 GFAP PAEP ADAM15 ATP6V0C FTL HAGH CRAT UPF1 HNF1A H2AFX ARPC2 EPHX1 PCYT1A SFPQ FKBP1A GRN YWHAH EIF6 POLR2E PAX8 NKX2-2 CEACAM3 ALAD TMBIM6 FTH1 PCBD1 MYD88 NDUFC1 STAM BECN1 PFKFB2 B4GALT5 EZH2 CDK8 LAD1 GRB7 HADH MUC2 LAMB3 PTPN3 AQP8 GABRA2	0.0739381	UP
LEE_LIVER_CANCER_MYC_UP	CYR61 CTGF PALMD CSRP2 LPL LY6E DMPK PDGFC CYP26A1 SLC13A3 SNTB1 GLUL SLC22A1 SLC1A4 CYP7A1 RPLP2 RPL12 MCM6 RPS16 LY6D SLC1A2 RPL36 TPR RPS24 MAT2A RPL28 GSTM2 RPS14 RPL13A CTSE CDCA3 LECT2 CISH ACTG1 GSTM1 FBXO21 DCLRE1A APRT PLAT CDK1 TMEM176B RNASE4 NUSAP1 RALB FDFT1 LCN2 CSTB MGST3 IDH3A KIF20A HMGCS1 HTATIP2	0.0740262	UP
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP	BCHE IGFBP5 SFRP1 PTGER3 EPHA3 SPOCK1 TRPC1 LEPR TMEM100 KCNMA1 BNC2 MS4A1 SCG5 KCNE4 PENK RELN FAM110B TNFRSF9 CCL22 ZFP2 BAALC HSD11B1 ALDH1A3 SLC1A3 RET PCYOX1L ABHD8 PTHLH ST8SIA2 DUSP5 BCAS3 NME7 BMP7 GALR2 ZC3H13 GDF10 GLI2 NTRK2 CDK17 SCN2A TSPAN32 TRPC3 PRTN3 SFSWAP MASP1 GRIA2 IL11 COL10A1 DMP1 CCR9 FOXD1 ALAS2 SLC28A3 DMC1 SLCO4A1 KCNJ3 PTPRS SLC25A4 SMARCD1 ADD2 PCSK5 RBPJL ELAVL1 GIGYF2 PTCH1 SERPINA7 DDX23 ZNF235 BDKRB2 EWSR1 ADAM18 DPH2 HSPA1A MBP SLC29A2 WIF1 THSD4 TAX1BP1 NEBL AQR FRZB BST1 KNG1 MED6 CTDSP2 ARHGEF12 RAB22A GPHN SPON1 SLC26A3 TNMD SERPINB5 DHCR24 L1TD1 TDGF1 MYB MPZL2 HNF4G MAP7 KIAA1324 GLCE REG1A	0.074698	UP
ZHANG_ADIPOGENESIS_BY_BMP7	GRB14 IRS1 GRB10 SH2B2 SGK1 AKT2 AKT1 PIK3R1 MYO1C HRAS MAP3K5 GRB2 PIK3C2A MAPK3	0.0749293	UP
REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	SLC38A4 SLC3A1 SLC36A1 SLC16A10 SLC38A1 SLC7A9 SLC7A1 SLC6A20 SLC7A6 SLC1A5 SLC7A8 SLC7A11 SLC6A14 SLC7A2 SLC7A7 SLC1A4 SLC6A12 SLC38A3 SLC6A6 SLC3A2 SLC6A15 SLC43A1 SLC38A2 SLC7A10 SLC7A5	0.0750839	DOWN
BIOCARTA_CARDIACEGF_PATHWAY	FOS AGTR1 EDNRA JUN PRKCB MYC PLCG1 PRKCA RELA ADAM12 HRAS RHOA NFKB1 EDNRB EGF EGFR EDN1 AGT	0.0752313	UP
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17	GCLM LIAS SLC39A4 SMAP1 YIPF5 HMGCS1 SLC39A9 DDT DPP3 SDHB RNF7 MRPS12 NDUFB7 MDH2 MTIF2 HSD17B4 FAM162A NDUFS3 LYPLA1 CAPN2 GRPEL1 TIMM13 CKS1B NR2F6 EIF4E2 PC COQ7 FUCA1 NDUFB6 TXNRD1 CMPK1 UQCRQ MRPS22 PSMG1 HSD17B12 MRPS11 BCAP29 MRPL34 TALDO1 PSMD13 LSM4 EI24 MRPS7 TMEM160 NDUFAB1 ALG5 DDOST MRPL16 BAG1 SLIRP NDUFS6 SAMM50 COPE IFI35 PSMD8 ALDH9A1 COPS5 MRPS14 NDUFV2 ARF4 STARD7 EIF4A3 PDCD2 FKBP1A ARPC5 MRPL18 HMBS TCP1 AURKAIP1 UFC1 UBL4A MAP3K7 TMED10 KRT10 MRPS15 WTAP CSNK2B TAF10 PSMA7 MRPS34 GOSR2 PHB2 PSMB7 SRSF9 FAM96B RPN2 UBA1 TMEM5 GSTP1 CORO1C PSMD14 LSM7 FAF1 ERP29 PSMB6 DCTN2 MRPL2 CKB CLPB PUF60 PDAP1 VDAC3 LRPAP1 DDX1 TRAM1 TWF2 TNFAIP1 TRAPPC4 CALM1 USP1 AQP4 XRCC5 MARCKSL1 INPP5A IMPDH2 DDX54 POLR3K NAA10 PTDSS1 PARL LMNA ACTB STUB1 ADSL RPS6KA4 ERCC3 ARL2BP UBE2S COPS6 SET CDK4 EXOC7 AKT1 BPGM TCEA1 RUVBL1 SAE1 MAPKAPK2 DRAP1 HNRNPD TPM4 CRYGD CENPB CYB5R1 TUBB ARL3 DLGAP4 NAP1L1 RAMP2 TMEM109 PIAS3 EVL TGFB1I1	0.0753798	DOWN
DAVIES_MULTIPLE_MYELOMA_VS_MGUS_DN	CDK14 LY96 S100A8 CTSG VNN2 RNASE6 ACTN1 CD27 PPBP FCER1G MERTK VCL TLR1 LILRB1 ADD1 GLUL DOK1 ARHGAP1 SLC7A7 NPC2 MYH9 TMSB4X CAP1 LASP1 SAT1 MARCKS LITAF	0.0754781	UP
PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_UP	NR4A2 DFNA5 MFAP4 MEOX1 EVI2A FLI1 DSE ZFHX3 PDP1 KCNAB1 RBP1 NOV RPL39L CA6 OXCT1 AHR CCR5 CALCRL IL2RG ATF4 FLT1 INSIG1 FOXG1 FAM46C KCNN4 TATDN2 PDGFRA EPHB2 IDI1 ENPEP CYP51A1 SOAT1	0.0755315	UP
SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_DN	FOS FRY DIXDC1 LAMB2 LTBP3 DYNC2H1 NME5 STAT5B CRTC3 ZFP2 CX3CR1 CYBRD1 CRY2 WDR19 DEAF1 CIRBP C11orf63 IFT46 ZNF862 AKAP11 STARD13 SMARCA2 SYNC TBC1D17 AASS CTDSP1 NYNRIN DZANK1 TPT1 ECHDC2 SESN1 ZNF395 MPHOSPH8 SIRT3 BBS1 CASP9 SNX1 RUNX1 IFT88 ARHGEF12 SLC24A1 RNASE4 NF1 TUBGCP4 NBR1 ARHGEF40 KIF13B MARCH8 PIGV	0.0756726	UP
MIKKELSEN_MEF_ICP_WITH_H3K4ME3_AND_H3K27ME3	SYT1 MEIS1 SACS TMEM100 SERPINI1 CORO1A CALY IDO1 CNTNAP1 NOL3 NPY2R FRMD4A EXTL1 PCSK1 NOL4 OPCML ADM2 KLHL1 MCHR1 KCNA4 CACNB3 PTH2R NPY1R KCNJ2 PTPRR	0.0757521	UP
REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION	WARS2 DARS2 PPA2 NARS2 LARS2 IARS2 HARS2 SARS2 QARS TARS2 YARS2 KARS RARS2 CARS2 GARS FARS2	0.07578	DOWN
BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP	XK ECT2 CENPA KIF4A NEK2 DLGAP5 SLC26A2 OIP5 MAPK1 MKI67 ABCG1 ARFGEF2 TWF1 BUB1B TFRC UPF3B SMC2 ARPC1A CCNE2 SLC50A1 MCM2 KIAA0100 DDOST TYMS SLC38A1 SFN RRM1 PTH2R NPC1 NARF DBF4 SLBP FEN1 H2AFZ USP1 TUBG1 SUZ12 MCM6 IARS UBE2S MCM3 RRAGD HLTF IGF2BP3 SLC39A6 NDUFA4L2 COCH TFPI DNAJC6	0.0761054	DOWN
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_8	NR4A3 FNBP1 XPA SET TSC1 NUP214 PTCH1 ABL1 FANCC CDC42EP1 SYK	0.0761141	UP
HOQUE_METHYLATED_IN_CANCER	PTGS2 TIMP3 SFRP1 APOD CADM1 PAX5 SNRPN TWIST1 RUNX3 APOC1 SFRP4 DAB2 SOCS3 RBP1 CDH13 HIC1 SFRP5 RARB GH2 CCND2 TIMP2 GATA4 WT1 FABP3 RASSF1 SOCS1 SEZ6L CDKN2A TFAP2A VCAN IL17A MGMT DRD4 MLH1 ESR1 CALCR CREBL2 GFAP GSTP1 FOXN2 SFN ME3 QDPR BRCA1 EDNRB CHFR FHIT CDKN2B APC FANCF HOXA5 BMP2 CDX1 CDX2 CDH1	0.0761763	UP
SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN	UCHL1 FGF13 FN1 DKK3 SPP1 PNMAL1 IRS1 LDOC1 MAGEH1 IFI16 ITM2A UCP2 SRGN FZD10 CD44 PMEPA1 ARMCX6 INHBA PDZK1 SLC6A15 CFI C11orf58 SPOCK3 MID1IP1 ABCA1 SLC1A4 LZTS1 DNAJC12 CDC16 STAT3 FKBP11 S100A2 NXPH4 VPS37C STAT1 EPAS1 HSPA1A CRY1 MAP2K5 THBS1 RAB27A TBPL1 FHL2 IL13RA1 TPD52 PLIN2 MAOA EPCAM SPINT2 ANXA4 PLAC8 HTATIP2 AKR1C3	0.0761813	UP
SEIDEN_MET_SIGNALING	CLCN3 ABCC4 TM9SF3 PRPS2 RAB11A RNASE4 CAPRIN1 CNOT8 KIF2A CCNH SFPQ CAP1 ITGAV CCT8 HAT1 API5 SEPT2 IFITM1 CSE1L	0.0761982	DOWN
OUYANG_PROSTATE_CANCER_PROGRESSION_UP	FOS JUN CD81 PRKCB JAK1 MAP3K1 STAT3 HRAS STAT1 GRB2 SYK CDC42 ARHGAP5 AVPI1 PLCE1	0.076264	UP
ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF	FOS FOSB PTGS2 NR4A2 GEM ATF3 SDPR FERMT2 NR4A1 DLC1 RGS2 CRIP2 VGLL3 HBEGF NR4A3 DUSP1 PPP1R15A FBXL2 PYGM RBMS1 BHLHE40 DUSP14 SEMA3A MAFF PFKFB3 JUNB CXCL2 PER1 PDP1 PROS1 IER3 IL6 HIVEP2 CEBPD EPHA2 STEAP4 CSNK1E SOCS3 CXCL1 DENND3 TRIB1 ZFP36L1 DBP CAMSAP1 DUSP5 TNFAIP3 ADAMTS9 CCL20 SERPINE1 KIAA0040 MMP19 FKBP5 ZNF202 ETS1 SNRK TP63 RORA MAP3K8 PHLDA1 PLK2 NAB1 IL1B NRG1 SBNO2 BIRC3 PPFIBP1 SLC22A13 ELL2 MCL1 CCNL1 NFKB2 KDM6B CLDND1 KLK6 ATXN1 OLR1 PLAUR SYT12 MBNL2 IL1RN PER2 WEE1 STX11 RPUSD2 IPPK SERTAD2 YRDC RAP2B TIPARP UGCG BCL3 RASA2 TACSTD2 SH3BP4 TLE3 JAG1 IL1RAP GABPB1 RND3 ZC3H12A CLDN1 IL1A AFF1 MAFK CASP9 MBP IGF1R ETS2 CSNK1D PANX1 NFKB1 TJP1 FRMD4B RUNX1 DPP4 PELI1 SMAD7 HOXA1 STK38L EZR RAPGEF2 ADM CD55 FOSL2 HES1 TGIF1 PTP4A1 SEMA3C SLC2A1 KLF4 FNDC3A CHMP1B RCAN1 VSNL1 TXNRD1 LMO7 EIF2AK3 EDN1 TOB1 TFRC RIPK4 JOSD1 ELF3 ZBTB38 DNMBP TMEM2 KLF13 SLC20A2 NDRG1 BLZF1 KLF3 ASAP2 SLC20A1 WWC1 PLAC8 HRH1 GALNT7 COBL CLDN4 ITGA2 C3orf52 TJP2 BTBD3 DMBT1 EMP1 F2RL1 GATA6 MTM1 KRT12 PSD3 FOXA1 APOBEC3B OCLN	0.0762868	UP
ZHAN_MULTIPLE_MYELOMA_MF_DN	PDZRN4 AMIGO2 MOXD1 CHST11 ENAH TNFAIP8 SYNGR1 DOCK9 APH1B PRKCA CREB3L2 SEC62 FAM3C ESRRG PTCH1 ITSN1 DKK1 CAMK1D MTDH RAD17 SLC12A8 RAPGEF2 STXBP6 ALDH2 TRANK1 SCAPER	0.0763247	UP
REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS	FOS JUN MAPK10 MAPK11 MAPK8 ATF2 MAPK9 MAPK3 MAPK14 MAPK1	0.0763435	UP
KYNG_ENVIRONMENTAL_STRESS_RESPONSE_DN	COL17A1 FUT4 CTNND1 SOX9 SGPL1 CNKSR1 ZNF507 SLC30A5 NCOR1 CEPT1 SYK HSD17B10 USP1 SLC18A2 HNRNPC GABBR1	0.0763865	DOWN
RODWELL_AGING_KIDNEY_DN	CTH FMO5 PCLO TOX3 CEP70 BCKDHB TMEM38B PHYH NLK GMNN SELENBP1 TMPRSS2 TSPAN7 NDUFS1 NAA35 DLAT ERLIN2 ECI2 AK2 CPEB3 CLDN8 FBXO3 MUT TPD52 ATP5G3 RHOBTB3 IMPACT SP2 UCHL5 TRPM6 YOD1 UAP1 ABCA5 ISCA1 CYCS NNT CSNK2A1 HADHB ENOSF1 NF1 SCML1 LRPPRC WDR61 ISOC1 CCDC93 EGF AMT AUTS2 COX7B ATP5A1 NEDD4L PPFIA1 ZNF711 APLP2 KNG1 ZNF253 OAT SIAH2 RBM14 COX7C NEBL SLK GOT2 ZBTB43 RTN4 MTO1 ATXN7L3B CCNB1IP1 FBXO21 PDE3B PEBP1 ADH5 GAD1 SLC25A36 ABTB2 SHANK2 ADCY1 AMPD3 TMEM80 SLC4A1 HDAC6 ESRRG GNAS RPL10 C3orf14 AASS KLHL24 SOHLH2 DCBLD2 KLF9 KANK1 LDHB DBT CACNB2 OXCT1 SRR NUDT7 GNG7 FOLH1B KLHL3 GABARAPL1 FXR1 BMP7 CACNA2D3 MTR PRKAA2 WNK1 PALM GHR SLC16A7 CRABP1 SULT1C2 MPPED2 GPRASP1 LPL THSD7A PTGER3 PEG3	0.0763967	DOWN
WALLACE_PROSTATE_CANCER_UP	AMACR BDH1 PRSS8 AHCY ST14 TPD52 UAP1 SOX4 DAP SLC25A6 HPN TSTA3 PPP3CA POLD2 FASN LIG3 EIF3I ODC1 MYC GDF15	0.0765454	DOWN
WALLACE_PROSTATE_CANCER_RACE_DN	OCLN IL20RA FRK NQO1 PCLO GLTP MEST SLC39A4 ELOVL6 CBR4 PLOD2 ZNF654 TRIM2 ENPP4 PRKG2 DHFR CHKA NARS2 MTMR2 LGALS8 VANGL1 TSGA10 RBM3 ENOSF1 RABIF ADI1 ZNF606 ZNF443 KLHDC10 EIF2AK1 STYXL1 SCCPDH PCGF3 SRD5A3 GPATCH2 SLC29A2 FAM134B ITGB3BP PDE3B SLC35E2 EIF2S1 ZMYND8 USP6 ADRB1 TLE1 EIF1AX CELF1 MAPK8 NAIP RPL37A RHOD RABEP1 VPS53 GTF2F1 ARL17A RAB3GAP1 INO80B ST20 EIF2S3 EIF4B PYGL PIK3CA PTK7 PATZ1 ZNF467 MARK1 HS3ST2 INHBB CDR2L PKIA FMO2 LIMCH1 CSGALNACT1 RTN1	0.076606	DOWN
REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION	MGAT4A EDEM3 MGAT4B SAR1B MPI MAN2A1 PMM1 MLEC STT3A ALG6 SEC23A ALG13 B4GALT5 GMPPA UGGT1 DOLPP1 MGAT2 SEC24B B4GALT4 MAN1A1 DAD1 DPAGT1 PGM3 EDEM2 B4GALT3 MANEA DPM3 ALG5 DDOST PDIA3 ALG8 ALG3 PMM2 ALG9 DPM1 GANAB B4GALT1 MAN1B1 RPN1 CANX SEC13 GMPPB DPM2 LMAN1 PREB CALR RPN2 SEC24D MGAT5 SEC24C EDEM1 MOGS UGGT2 DOLK SEC31A ST6GAL1 PRKCSH MGAT3 ALG12 MCFD2 MGAT1 MAN1A2 B4GALT2 B4GALT6 FUT8 ST8SIA3 ST8SIA2 MGAT4C TUSC3 MAN1C1 GFPT2	0.0767442	DOWN
REACTOME_APOPTOTIC_EXECUTION_PHASE	OCLN CASP7 CASP6 HIST1H1C DSG2 TJP2 DSP CDH1 CASP3 PRKCD APC LMNB1 BIRC2 CASP8 GAS2 DNM1L STK24 BCAP31 H1F0 DSG1 TJP1 BMX DFFB HIST1H1D KPNA1 HMGB2 CTNNB1 PTK2 LMNA HMGB1 DSG3 FNTA PLEC PAK2 PKP1 KPNB1 HIST1H1B HIST1H1A DFFA SPTAN1 HIST1H1E ROCK1 ACIN1 ADD1 SATB1 GSN PRKCQ VIM MAPT	0.0771787	DOWN
REACTOME_S_PHASE	RFC5 CCNA2 GINS1 ORC2 CDK7 PSMC6 CDC6 CKS1B SKP2 PSMB8 CDKN1A ORC5 PRIM2 ORC4 POLD4 CCNE2 PSMD3 PSMA5 GINS2 PSMD7 MCM4 PSMD13 PSMB10 CDT1 PSMD10 ORC1 MCM2 PSMD11 PSMA3 RFC2 PSMC4 PSMD8 RPA3 PSMA6 POLE2 PSMF1 CCNH PSMD5 PSMB3 PSMA1 PSMA4 RFC3 PSMD9 PCNA CCNA1 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 POLA1 PSMD2 PSMB5 ORC6 POLD2 PSME4 PSMD14 SKP1 LIG1 PSMB6 POLD3 MCM7 PSME2 CDKN1B PSMD12 PSMB1 PSMD6 PSME1 RB1 DNA2 FEN1 PSMB4 PSMB9 GINS4 PSMB2 RPA1 PSMC2 PRIM1 PSMC5 CDC45 PSMD4 PSMC1 ORC3 WEE1 CDK2 MCM6 RPA2 RPS27A MAX POLE MCM5 POLD1 CCNE1 UBA52 CDK4 MNAT1 MCM3 CUL1 CDC25A RFC4 POLA2 CDC25B MYC CCND1	0.0773048	DOWN
REACTOME_KERATAN_SULFATE_DEGRADATION	OGN PRELP OMD LUM FMOD ACAN KERA HEXA GNS HEXB GLB1	0.0773191	UP
HILLION_HMGA1_TARGETS	FOS TAC1 CLU CXCR4 CRIP2 PMP22 GPX3 IRS1 CXCL2 TGFB3 P2RX1 C5AR1 GHR GABRB1 HTR6 ACHE NFKBIA HSPB1 TACR1 GPX5 TIMP2 ATP6V1F LIMK1 MOS SLC6A11 MYCN GRM1 AKT1 DCC RPS11 RPL19 HSP90AB1 RPL11 RPL13 CHRNB1 RPS17 PNLIP EEF2 GPR6 GLRA1 RPL21 ESR2 GABRR1 RPS19 MAK RPS12 GSTM2 STAT3 HRAS RPS3A VCP ATP5G2 NME1 ID2 MIF NME2 CXCL5 PSMB6 B2M RPL36AL CD3G PCNA ARAF HSPD1 CFL1 PSMA1 COX4I1 ID1 TK1 SOD1 EDNRB AKR1A1 ALDOA ID3 INSR IGF2R ATP5F1 ATP5G1 NPY TFRC GMFB SLC25A5 ERBB2 COX5A NEO1 NRAS	0.0773377	UP
SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_DN	CCL21 AEBP1 COL1A1 COL1A2 SPARC MXRA8 CCDC28B APOC1 CD247 ENO3 DEAF1 TCAP GMPR CCL27 ZBTB17 PLEKHA5 MYL1 ACSBG1 ITM2B ANKRD17 GRN MDH1 HOXA7 GPT SH3GLB2	0.077346	UP
KANNAN_TP53_TARGETS_UP	NEFL ATF3 FEZ1 LOXL1 ACTA2 IGFBP6 SMTN BCL6 LCAT PLK3 BTG2 APLP1 ENG GDF15 DMPK APOC1 ABCA3 NDN TMSB15A CARTPT NINJ1 BBC3 SLC3A2 DDB2 PDLIM4 NHLH2 MAN2B1 VCAN DGKA ZNF7 HRAS PMAIP1 QSOX1 SCGB2A2 GADD45A PCNA SMAD7 SURF1 SCRIB CTDSP2 EXT2 FHL2 DCAF7 CDKN1A FAS VIPR1 BAK1 TAX1BP3 PRKAB1 MARCH8 LSR PLIN2 CES2 GALE TST HIST1H2AC SPAG1	0.0773535	UP
MAHADEVAN_IMATINIB_RESISTANCE_UP	GREM1 NNMT AXL SPOCK1 SCN3A DKK3 KYNU SERPINE2 BAMBI PDGFC SPANXC SPANXA1 CYTL1 CRIM1 CXCL14 ALDH1A1 CD24 MYO10 SLC1A1 HSD17B2	0.0778019	UP
REACTOME_COMMON_PATHWAY	THBD F13A1 PROS1 F10 FGB PROC F5 PF4V1 FGA F13B F2 SERPINC1 FGG PF4	0.0778787	UP
YAMASHITA_LIVER_CANCER_WITH_EPCAM_UP	VIL1 XK MPZL2 TTK DSG2 ABHD3 EPCAM SCARB2 AHCY TRIM24 SRPK1 RPS4Y1 CPOX POLR2E MRPL3 GNPAT RPLP0 TOMM20 SPTBN1 RPSA DKK1 RPL23A RPS3A RPL13A AFP EIF3F RPL28 RPS12 RPS10 RPL7A HNRNPA1 RPS24 RPL31 RPL29 RPL6 RPS3 TAF1D RPS4X RPS27A RPS7 RPL17 RPL9 GNAS XPO7 RPL35 MDK OXT PTPN12 PHF20 FMOD BAMBI PEG3	0.0779318	DOWN
SESTO_RESPONSE_TO_UV_C3	PTGS2 ATF3 HBEGF DUSP1 IER3 IL1B BRD2 PMAIP1 HIST2H2BE EIF2S1 RND3 H2AFX MYD88 CYCS PHLDA2 TAX1BP3 ATP6V0D1 SOX9 MAD2L1BP	0.0780031	UP
DOANE_BREAST_CANCER_CLASSES_UP	LRRC31 FOXA1 HMGCS2 FA2H TOX3 ABCC6 AGR2 PBLD TFF3 TNIK PEX11A HGD GALNT7 CPD DCXR SULT1A1 GPD1L CEACAM6 C1orf115 SCUBE2 FGFR4 CDK12 MLPH PDCD4 CYB5A TMEM62 SIDT1 LASP1 TRIM3 GGT1 XBP1 TARP MPHOSPH6 CRAT ALDH3B2 TRIL FASN CYP4F8 PRLR HPX ECHDC2 SPDEF CRISP3 RND1 AZGP1 ALDH4A1 ABCA12 CLCA2 REEP5 PIP GALNT6 NEIL1 RASL10A SERHL2 FAM174B DHRS2 TBC1D9 AR CIRBP TFAP2B KMO LRIG1 CERS4 SLC16A2 ALCAM ABCA8 KCNMA1 C16orf45 RHOB APOD	0.0780775	DOWN
GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN	KCNMB1 ATF3 CES1 PCOLCE2 PDE4B FAM107A ITIH5 KLF2 SLIT3 SH3BGR APLP1 LCP1 RASGRP3 SOD3 LAMA5 HOXD13 HLA-DMA SLC2A3 TACC1 AFF3 ENPP2 IQCG NPTXR CSDC2 WNT7B TGFB2 SEMA3D DDX18 COL2A1 FBXO2 PGBD5 FKBP10 DCC VGF UPK3B COL19A1 EFNA5 CAMK4 SLC4A10 LMF1 ESR1 WSCD2 PYCR1 CEP72 FAM46A CD59 ITGB5 SEMA3C TSPAN13 RACGAP1 ACOT2 HIRA ASRGL1 ENDOD1 PHLDA2 PARM1 EPPK1 SCARB2 SLC22A18 CDH17 CXADR VAV3 MYO1D CYP2C18	0.0780901	UP
REACTOME_SIGNALING_BY_ROBO_RECEPTOR	CAP2 SLIT2 ROBO1 EVL ENAH SRGAP2 GPC1 CLASP1 ROBO3 SRGAP3 PAK2 PFN1 PFN2 ABL2 NCK2 VASP ABL1 PAK6 PAK4 CAP1 RAC1 CDC42 SOS1 SOS2 NCK1 PAK1	0.0780999	UP
REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT	STAM2 CHMP2B CHMP5 VPS4B CHMP3 CHMP2A VPS37B STAM TSG101 SNF8 VPS28 CHMP4A VPS4A HGS VPS37C CHMP6 RPS27A UBA52 CHMP7	0.0785994	DOWN
MORI_PRE_BI_LYMPHOCYTE_UP	E2F8 EMP1 HMMR PRC1 KIF4A TTK AURKA MELK HMGB3 ENPEP TOP2A DTL TXN GRB7 CDC20 CCNB2 MKI67 IDE DBI MGST2 GZMA CKS1B LMNB1 CDKN1A RAD51 RACGAP1 CRIP1 MCM2 CDK1 SMC4 SOCS2 ACTN4 NCAPH PRDX4 UBE2C KPNA2 GAPDH HNRNPAB RRM1 H2AFX RRM2 LIG1 MCM7 CDCA3 MIF H2AFV RBBP4 TUBB4B SQLE HMGN2 HSPBP1 CCL5 DNTT PSAT1 MCM6 RAN SMARCC1 STMN1 NUCKS1 RASA4 IGLL1 GSTT2 TUBB FCER1G LEF1 MTHFD2 ANP32E KANK3 ENG SLC29A1 PHGDH TUBA1A RAMP1	0.0787051	DOWN
VALK_AML_CLUSTER_6	DPYSL3 CORO1A FAM110B RGS10 NT5DC3 PECAM1 FOXF2 BST2 ADCY2 HLA-DRA HLA-DPA1 FOXC1 SNCAIP PIEZO2 CD74 SLC27A6 KIAA0930 LTBP1 FTO FAM174B TTC27 XPA GPC4 RSL1D1 HOXB3 DPPA4 PLXNB1 SMC4 TUBGCP4 CAT HIGD1A CEP70 DSC2	0.0787525	UP
GENTILE_UV_HIGH_DOSE_UP	ATF3 TSC22D3 HBEGF RRAD MAFF ACTC1 FSTL3 HTR6 SFI1 COL13A1 ISG15 NUPR1 IL11 MMP3 RPS20 PMAIP1 SRSF9 GADD45A HIST2H2AA3 TCEB2 SAT1 LRBA HIST1H2BI HIST1H2BE PRSS3	0.0787738	UP
CROONQUIST_NRAS_VS_STROMAL_STIMULATION_UP	SYNM SV2B RNASE6 GATM IQSEC1 CD86 ETV1 CX3CR1 RASGRP2 AMPH SPI1 DUSP6 CCR2 DUSP4 CYBB NCF1 MIA MC1R TBC1D9 ACP5 ARHGEF2 PRKACA RNF2 MCC SLC7A7 PLEC ALOX5AP KCNN4 ZER1 SNAP23 ARHGAP5 RHOBTB3 TRIM25 ZNF217 CEACAM1 NRAS BCKDHB	0.0788162	UP
REACTOME_PLATELET_HOMEOSTASIS	KCNMB1 GUCY1A3 GUCY1B3 PDE2A PDE1A GNG11 PECAM1 GNB5 GNG3 P2RX1 KCNMB4 PDE5A FGR SLC8A2 ATP2B2 PTPN6 PDE1B GNG7 LRP8 PPP2R5B ITPR2 APOB KCNMB3 TRPC3 NOS3 PRKG1 PDE3A PLA2G4A PTGIR PDE6G GNB3 TRPC6 PDE10A NOS1 GNAS STIM1 ATP2A1 KCNMB2 SLC8A1 GNG4 PPP2R5C PDE9A PPP2R5D PDE11A GNB1 GNG13 PDE6B ATP2B3 NOS2 GUCY1A2 PPP2CA GNB2 PDE3B PPP2R1A ATP2A3 GNGT1 PPP2R5E TRPC7 PPP2CB PPP2R5A GNG5 MAPK14 ATP2A2 ITPR3 PPP2R1B PRKG2 GNG12 PDE6A	0.078845	UP
NIKOLSKY_BREAST_CANCER_6P24_P22_AMPLICON	CAP2 ID4 CD83 PHACTR1 KIF13A GFOD1 RANBP9 NOL7 SIRT5 DEK NUP153 FAM8A1 TPMT	0.0789292	UP
ZHENG_IL22_SIGNALING_UP	RTN1 TAC1 THBD IL33 CFD C3 PFKFB3 S100A8 TIMP1 SLFN12 STOM INHBA TTC9 TGM1 S100A9 CELSR1 STXBP5L ARG1 SBNO2 CD14 OXTR OLR1 FZD1 HP CD38 CXCL3 CCL5 MYH1 CLDN1 PLAT PF4 CFB PTX3 CXCL6 RPS6KA5 ALDH1L1 SLPI APAF1 REG3A DSC2	0.0790795	UP
LI_CISPLATIN_RESISTANCE_DN	CHRDL1 AMIGO2 CFH PCDH7 LAMA4 CFHR1 TDO2 IDO1 BAMBI SKAP1 GPC3 TES FZD8 PSG11 FOXG1 GSG1 BCAN MMP10 JAG1 ADM SEMA6A EDNRB PPIC MARCKS AKR1C1 MEST AKR1C3	0.079324	UP
POOLA_INVASIVE_BREAST_CANCER_DN	SYNM MGP TPM2 CNN1 PPP1R3C ITGA7 NAV3 LTF SORBS2 ITPR1 CLEC3B SERPINA3 DKK3 HBB EREG LTBP3 ZDHHC11 MYLK MPPED2 MAPT FGF2 BST2 GATA3 TESC KLK10 STC1 PTN CELSR2 AK5 MIA SERPINA5 LTBP4 SLC27A6 MATN2 SLC39A6 CYP4B1 CRLF1 STC2 PDZK1 RABGAP1 GFRA1 NPY2R XYLT2 CELSR1 GRP FRMD4A CAPN3 WFDC2 GSTT1 DCT MSX2 GRIA2 FBXO2 SYMPK CYP1A1 OXTR PEX6 KRT17 ECE1 SLC25A37 EXOC7 PIK3R1 TDRD12 CHI3L1 ERBB4 KCTD2 CACNA1D DST CITED1 PKP1 IGSF1 KRT5 RABEP1 FABP7 ESR1 DNAJC12 KDM4B ALDH4A1 TP53I11 TIMM44 COL4A5 TF AZGP1 CDK10 CPB1 TAPT1 SEZ6L2 VTCN1 SYT17 CD151 TRA2A ITGA3 IFT140 KRT6B PDGFA CD59 IGF1R SSH3 ACSM1 WIF1 PLAT PPIP5K1 FRZB SDC4 NEDD4L FGFR3 NPY1R FLNB WNT5A SCUBE2 ANKH UGT2B28 ARHGEF5 IGFBP2 LGALS4 CA12 DACH1 INPP4B SERPINB5 IL17RB HIST1H2AC BMP5 LAMB3 MYB EDN3 ANPEP NQO1 CLMN ACADSB HMGCS2	0.0795463	UP
JEPSEN_SMRT_TARGETS	EGR1 PPP1R1A LIMS2 SPARC TIMP1 RBP1 TNFRSF12A APOE DSCAM ELAVL3 PDLIM4 MGA DCX KDM6B ABCA1 SYT12 METRN NTNG1 CGREF1 TCF25 ESD ARL8B ZBTB5 SPRY4 PDGFA HMGA1 IGF2R NIF3L1 HMOX1	0.080081	UP
TSAI_RESPONSE_TO_IONIZING_RADIATION	DPYSL3 TSC22D3 CCL21 TGFBR3 AXL HBEGF CDKN1C FN1 NR4A3 VEGFC CCL3 TCF21 FGFR1 JUNB CD79A BTG2 COL4A2 CCL18 TNFAIP8 COL6A1 GDF15 CD83 CCL4 FCN3 PLCG2 DUSP6 CCR1 PTN MYC MSC TNFAIP3 CCL20 PTPN6 SIPA1 CDK6 CARTPT BATF RFX5 RABGAP1 STAT5A BBC3 LZTR1 CCNI IRF4 SGK1 RORA NFKBIA SNAPC2 PRMT1 TRAF1 PLAU AHR MDFI IL2RB ZNF274 CCNK DDIT3 DDB2 BIRC3 RELA PTPN11 NFKB2 DLX2 ROCK1 BTG1 NFKBIE PTPN22 PKD2L1 XPC CCNF ZBTB48 ATF5 HOXC5 RANBP1 MAX ARL2BP STK4 TNFRSF8 IFITM1 KIF20B CCT4 FAM134C NCOA3 CD80 ZNF85 ENC1 TRRAP CXCL10 CCT7 IRF9 POU5F1 TANK IFNGR1 NFE2L1 POU3F4 PLK1 ADORA3 RB1 PLOD3 CLK1 JAK2 STAT1 KRT14 DKC1 TLE3 CFLAR CRAT CD59 CGRRF1 SMAD3 MSH2 PCNA ZNF141 ENO1 NFKB1 GRN PTTG1 EP300 UBE2C CCNG1 AKAP5 CDK1 CD164 TGIF1 COX7B NDUFB5 MED21 KLF4 CCNG2 CCNE2 CDKN1A RPS6KA1 FAS LGALS3 PLAGL2 CASP1 TNFSF10 TFDP2 PPM1D TP53I3 KRT8 KRT19 ITGA2 RAD50 KLRC2 MAP7	0.0810386	UP
HOLLEMAN_ASPARAGINASE_RESISTANCE_B_ALL_UP	CCDC69 LPCAT1 IGFBP7 GATA3 CLEC11A NTRK3 TPM4 GLTSCR2 RPL4 RPL5 EIF3D RPS5 RPL11 RPS3 RPL6 EIF3L RPL3 RPL7A FAM46C FBL RPL13A EEF1G EEF1B2 EIF3K BCR	0.0812055	UP
IKEDA_MIR30_TARGETS_UP	DMD MYH10 HDGFRP3 NCAM1 BNC2 IRS1 RRAD ELMO1 SEMA3A DPYSL2 JUN GFPT2 PIP4K2A ASAP1 LRRC17 ACTN1 ARHGEF6 MAP4K4 NEDD4 SSBP2 DTNA NOVA1 SCAF4 CELF2 SNAI1 GNAO1 SLC4A7 BCL2 ACVR1 CDK6 MAF PPP1R12A BDNF SATB1 CCND2 ARID4B SLC6A6 ELL MAN1A2 USP47 XPO1 TAOK1 HIC2 NFIB PHTF2 USP34 RAP2C SON ITSN1 ARID4A AP3S1 CALM1 IRS2 KDM3A CHD9 USP15 RNF44 WDR7 CLOCK MAML1 CSNK1G1 CCPG1 TBC1D15 PTPN2 P4HA1 YWHAZ RASA1 UBE2J1 RAI14 DDX46 ARF4 PELI1 UBE2D2 FNDC3B UBE2V2 PAPOLA NFAT5 TFDP1 NRIP1 LRRC8D GTF2H1 PPFIA1 IER5 CAST FNDC3A KRAS MARCKS BECN1 PDCD10 B4GALT5 CNOT6 SEC23A GOLGA4 SEMA6D ATP2B1 NRBF2 DDAH1 WDR44 GALNT7 SOCS6 PLCB4 GNA13	0.0815667	UP
BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN	PTGS2 MGP AKAP12 SDPR HBEGF EREG IER3 EPHA2 CXCL1 GJA1 COL3A1 PHLDA1 BNC1 TNK2 LRRFIP1 PLAUR MTMR10 HSPH1 ANKRD1 AMOT F2R CHD1 FLNB POSTN ANXA3 TOM1L1 ECT2	0.0816177	UP
CERVERA_SDHB_TARGETS_1_DN	ZBTB16 PEG3 SCGN PEG10 CHODL TTYH1 CCR6 NPTX2 PLA2G7 FJX1 EYA4 ALDOC ITPR2 SOX2 CPS1 CADPS FTCD LYZ MMP16 SULT2A1 RPL13 F2 AFP ANGPTL3 HSPA1A FABP1 PPFIBP2 MEP1A ADH6 HMGCS2	0.0816506	UP
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP	APOLD1 HSD17B6 AKAP12 ATF3 FERMT2 TUBB2B ENO2 PTRF EGR2 SYT11 TMEM158 FHL1 ITPR1 CSRP2 CDO1 FLNC SERPINI1 DUSP14 JUN TUBB2A ZNF331 PLK3 COL1A2 HCLS1 NPTX1 LAT2 IL23A HSPA2 TIMP1 MAP3K14 PIK3CD TTLL7 CDR2L NNAT RGS9 MAFB NRGN LIFR RASGRP2 MAP4K1 MICA CARD14 APBB2 INPP5F IFFO1 MMP2 DPEP3 PMEPA1 ZNF571 TYRO3 CYP26A1 HABP4 SH2B3 SPHK1 VCX2 ZNF222 SKIL CLGN TSC22D2 EHD1 TIMP2 KLF12 SEC61A2 ODC1 SOCS7 CDKN2D ECM1 PGF STK10 HYAL1 IFI30 OXTR HDAC5 GDF11 BAIAP3 DAZL TEF TKTL1 DGKZ TDRD12 ZNF79 SSX3 SENP5 IRF7 CLIC3 MAGEB2 TUBA3C RPA4 C6orf106 ZMIZ2 CYLD ASB6 PAGE1 AKAP17A NRIP3 ALPP CGREF1 HSD17B1 TAF7L KCNV2 MAP2K3 STAT3 PISD SLC6A8 LUZP4 HIST1H3G MAGEB1 MAGEC1 SLC7A6 PLAC1 MT3 MAP1LC3B ATP6V0A1 ATP6V0C GOSR2 AK1 DNAJB2 PITRM1 TRIO MOK SSX1 TNNC2 ARF4 YKT6 SLC12A6 RBM34 KDELR3 AFF4 RAPGEF2 EHD4 OPTN MPZL1 PARP12 SPTLC2 BMPR2 GAB2 SMPD3 SYNJ2 CLTB PLIN3 MKLN1 CDKN1A SBNO1 FUCA1 GLS CD9 REPS2 MOSPD1 ATP6V0D1 DNMBP GCH1 ATP6V1D ORMDL2 LSR MLEC NMT2 ITCH HN1 HIST1H2BG ABHD2 NEU1 AGGF1 FKBP1B SLC9A3R1 HIST1H2AG HIST1H2BD KRT20 C3orf52 UPP1 NXT2 F11R STX3 HIST1H1C SPAG9 PRKAB2 CLMN KRT12 APOBEC3B PKP2	0.0818352	UP
REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	OCLN CASP7 CASP6 DSG2 TJP2 DSP CDH1 CASP3 PRKCD APC LMNB1 BIRC2 CASP8 GAS2 STK24 BCAP31 DSG1 TJP1 BMX CTNNB1 PTK2 LMNA DSG3 FNTA PLEC PKP1 SPTAN1 ROCK1 ACIN1 ADD1 SATB1 GSN PRKCQ VIM MAPT	0.0826275	DOWN
IRITANI_MAD1_TARGETS_DN	MTM1 E2F8 SLC16A1 AHCY UQCRC1 RAD23B MRPS18B DCTPP1 C1QBP CDK1 HSPA9 RARS ASS1 BABAM1 HNRNPH2 PPA1 NME2 RPSA SLC5A6 EIF1AX MYBBP1A LONP1 EEF1G APEX1 RPL22 FBL EEF1A1 RPL18 IPO5 EEF2 RPL29 RPL13 RPL10A MCM6 RPL12 DUT WDR74 POLD1 CAD RPL5 NPM1 GGA2 SRM	0.0829634	DOWN
BIOCARTA_IL6_PATHWAY	FOS JUN SRF IL6 CEBPB IL6ST PTPN11 JAK1 ELK1 JAK3 TYK2 STAT3 HRAS SHC1 JAK2 RAF1 MAP2K1 GRB2 MAPK3 SOS1 CSNK2A1 IL6R	0.0829669	UP
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP	PTGS2 PPP1R15A MAFF GABARAPL1 TNPO1 BPGM KLF6 MAFG C16orf72 BTN2A1 KIAA0232 ABL2 DNAJA1 HSPA8 NUP153 PRDM4 FOSL2 PTP4A1 RIT1	0.0829773	UP
REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION	NOTCH3 JUN MAMLD1 NOTCH4 CCND1 RBPJ NOTCH2 KAT2A E2F1 MAML3 TNRC6B CREBBP TP53 KAT2B SNW1 E2F3 MAML1 EP300 TFDP1	0.0831352	UP
REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE	CA2 CA4 CA12 CA1 CA7 CA3 CA9 CA5B CA14 CA5A CA6	0.0831512	DOWN
REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G	PSMC6 PSMB8 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 CUL5 PSMD11 PSMA3 PSMC4 TCEB2 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 RBX1 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PSMB4 TCEB1 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 RPS27A UBA52 APOBEC3G	0.0832475	DOWN
SHIPP_DLBCL_CURED_VS_FATAL_UP	CES1 MAP1B NR4A3 AKT3 HTR2B CHRNA3 APLP1 NTF3 NPTX2 SELE GATA1 ARC FUT1 GNA15 RORA PRKCG CHD8 MLC1 LTA FXYD2 CLCNKB SLC38A3 RAB40AL MYL4 EYA3 DRP2 ATP2A1 SLC11A1 CYP4A11 CTSE GPR12 SERPINB8 ZNF91 SOX4 FAAH AKR1C1 MMP1	0.0841104	UP
MCBRYAN_TERMINAL_END_BUD_UP	CNN1 TNS1 SFRP1 MYH11 EGR2 TNFRSF12A LY6D CDK1 IGFBP2 SDC1 EHF	0.0841648	UP
PHONG_TNF_RESPONSE_VIA_P38_PARTIAL	CDH19 TUBB2B TNC C8orf4 LHFP RGS2 KANK2 DUSP1 PCDH7 TRIB2 FZD7 DUSP10 IRS1 LBH BCL6 PDE8B LAMC1 EREG JUN TUBB2A MAFF CALHM2 JUNB CXCL2 CHST11 TPST1 KYNU TGIF2 ALCAM GLIPR1 KLHL21 IER3 IL6 DNAJB4 HIVEP2 CEBPD NR2F2 CXCL1 CD44 FLRT3 PTHLH IL27RA TNFAIP3 CCL20 SERPINE1 COL7A1 INHBA FJX1 IL6ST LDLR SPHK1 BDNF REL BTG3 PHLDA1 TSC22D2 PLK2 PLAU TGFB2 SNCA FOXO1 AGRN MCL1 NFKB2 TTC27 KDM6B NFKBIE KLF6 PLAUR INSIG1 SDF2L1 CYLD CXCL3 NBN PTGER4 HEY1 SERPINB2 NKX3-1 INTS6 STAT3 IL4R LIF DKK1 PMAIP1 TIPARP TANK KCNN4 TRAPPC4 ID2 TAPBP IRGQ RNF44 ZNF395 CREB1 FAM46A SQSTM1 ITGAV DNAJB9 SLC12A7 HERPUD1 SMAD3 BAHD1 BID TNFRSF10B CITED2 B4GALT1 HAS2 HEXIM1 MFHAS1 TNS3 THBS1 ID1 BAZ1A PTX3 FNDC3B HIVEP1 ADM RXRA PGRMC2 BIRC2 ID3 TCF7L2 FOSL2 NEDD4L IFNGR2 EGFR SEMA3C CCNG2 SSFA2 CDKN1A EFNB2 TOB1 PPIF RIPK4 LITAF SLC31A2 TNFRSF21 FGD6 HOXA5 BMP2 NAMPT SLC20A1 WWC1 PLAC8 SLC39A14 VDR C3orf52 AURKA LGR5 BMP5 ARL14 HOXA9 TGFA GABRA2 PITX2	0.0849104	UP
CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY	CR2 NOTCH3 FHL1 PCDH9 SELL BCL6 FGFR1 ARL4C ICOS EPHB6 TCF7 ADA MME FYB MX1 C2orf27A GFI1 DNTT NID2 PSPH H1F0 PRDX2 TMPO MXI1 TFDP2 DHCR24 HIST1H2AC HOXA9	0.085301	UP
SHEPARD_CRUSH_AND_BURN_MUTANT_UP	CYR61 FOS EGR1 PTGS2 ATF3 C8orf4 PDLIM3 IGF2 FN1 KLF2 KLF11 MMP9 ANGPTL7 MS4A4A JUN PFKFB3 JUNB PLK3 BTG2 RBP4 CEBPB SNAI1 HAUS2 IFFO1 DUSP4 MMP2 DUSP5 MEGF6 POLR1E SERPINH1 IMPDH1 CIC MYOG SLC16A6 PTP4A3 TSR1 GCNT4 CYP26A1 C6 PIM1 CDX4 PPAN SGK1 RASL11B GPD1 ODC1 TRMT1 DNTTIP2 BRF1 SLC3A2 FST NOL6 MCMBP WDR46 FTSJ1 TXNIP MAGOHB KRT17 DDX19A TUBA8 BOP1 SIX2 RNASET2 HTRA2 REXO2 RRS1 PWP1 ZNF593 PPM1H CYP27B1 MARS LYRM1 DDX51 RRP9 MANF DRG2 SRPRB GADD45B TP53 NOC4L ETF1 HSPA1L DDX49 RPL10L WBSCR22 FTSJ3 AGK FBL MDM2 SSR1 NOL8 NOL7 TSR2 FOXO3 MYBBP1A ANGPTL3 ID2 MKNK2 MRPL52 NLE1 TOMM20 IMP4 UTP3 PTGES2 RPS27L PES1 PHB2 SLC12A7 TSFM OLA1 IGFBP1 TAF9 SLC12A3 WRAP73 HIST1H3B ZNF330 VRK2 IMP3 QARS HSPA4 C21orf33 AK4 GAR1 EIF6 PTRH2 CYP24A1 CCNG1 SAMM50 HSPA9 CASP8 WDR12 ABCF2 ADAM10 SAT1 HES1 TIMM17A MRPS18A POP4 HARS2 BAX CCNG2 HEATR3 DNAJA3 RCAN1 MRPL22 ATPIF1 MRPS18B EIF4E MRPL12 NIP7 PHLDA2 TOB1 TMEM106B AKR7A2 ELOVL1 SEC23B BMP2 CORT CLDN4 SHMT1 CYP51A1 FLVCR2 AP1M2 PDSS1 CTH	0.0853488	UP
KEGG_FOLATE_BIOSYNTHESIS	GGH DHFR SPR GCH1 PTS ALPI QDPR FPGS ALPP ALPPL2 ALPL	0.0856629	DOWN
BROWNE_HCMV_INFECTION_24HR_DN	TPM2 TIMP3 IGFBP5 TFPI CAV1 ACTA2 CALD1 KCNMA1 ATP2B4 COL5A2 ANGPT1 PAMR1 LAMA4 S100A4 FBN1 LAMC1 GJA4 COL6A3 PDLIM7 SLC16A4 PTPN13 OLFML1 PTPRM ABCA8 FAM65B SLC16A2 RPS6KA2 GRIK2 PDGFRB SSPN BLK FADS1 PARVA CD44 RECK DBP TGFBR2 CDH13 NOV LPAR1 ERCC2 FGF1 CROCC IGFBP3 GDF10 POLR3G KIT KIAA0930 FGF8 PRKCA CXCR2 MXRA5 COL13A1 B9D1 PRKG1 ABCC1 GSTT1 TAF1B MXD4 BTG1 GPR176 AP4S1 CPS1 TEAD1 CDON ARHGEF9 DST UROS GAS6 SSH1 CRIM1 DDX17 N4BP3 BTN3A3 PKLR GPX1 MGMT MYH8 YLPM1 HIPK2 HOXA11 ACTB GRIA3 BNIP3L SLC14A1 COL8A1 UGCG ATP5G2 DRD3 SGCB NIPAL3 TM7SF2 B2M CFLAR OAZ1 PDE1C FIG4 CD59 PRSS23 BACH1 ALDH1A1 PTEN UBB SPAG5 THBS1 BST1 ATP5H BIRC5 CCNG1 EXT1 CTSO TKT S100A10 SEMA3C BCAP29 RIN2 FDPS PRIM2 CDKN1A LGALS3 RDH5 RRAS2 SEPT11 NR1H3 TMEM187 DIAPH2 DNMBP FBN2 MGST3 MET DDAH1 SEMA5A ECI1 MTMR11 VWA5A CA12 ANXA4 AP3S2 TP53I3 SUCLG2 ITGA2 MMP1 MEST PRKAB2 HOXA9 ACOX1	0.0856991	UP
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_22	MN1 PDGFB MKL1 SEPT5 PATZ1 CLTCL1 NF2 MYH9 EWSR1 BCR EP300	0.0857353	UP
NATSUME_RESPONSE_TO_INTERFERON_BETA_UP	TIMP3 IGFBP5 IGF2 RGS2 TGFBR3 GRB14 PTPRZ1 VCAM1 CHST15 ICAM2 CREM MAPK10 MAP3K14 IL11RA IFITM3 ENO3 IGFBP3 MMP7 PFDN5 AMPD2 ETV4 DDIT3 MC4R CLK2 AKT1 TNFSF14 TLX1 RPGR FASLG CXCL9 DST FGF5 KDM5A PER2 HRK TP53 TP53BP2 IL15RA BCL3 BCL2L2 EIF2AK2 STAT1 EPHB3 HSP90B1 DNAJA1 CALM2 TRAIP CASP9 PDGFA IFNG HLA-C SFPQ CDK13 HLA-B NFKB1 HSPA4 IRF1 NCOR1 HSPA9 FOSL2 FAS FGF9 PPARA TFF1 MAPK1 APAF1 MAP2K6 CASP7 IL18	0.0861281	UP
MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN	PTGIS SFRP1 ID4 APOD RGS2 PPP1R3C EDNRA NID1 CDH5 BCL6 ARHGEF3 TNFAIP2 VWF GATA3 DAPK1 TCF7 PTN AREG PHLDA1 APOC2 NFKB2 TYR CHI3L1 CSN3 RBM5 NID2 PFN2 SFTPD PDK4 MBTPS1 RAB27B BCL3 RBBP4 ID2 KITLG IFIT3 MT2A ALDH1A1 PTTG1 PTX3 LRP5 ADM SFTPB GCLC SOD2 VAPB CD9 GZMA LCN2 SLPI ABCC3 SLC12A2 SLC9A3R1 SPINT2 IDH1 CLDN4 CDH1 KLF5 ERBB3 HSPA1B	0.0861462	UP
REACTOME_APOPTOSIS	OCLN CASP7 CASP6 HIST1H1C DSG2 TJP2 DSP CDH1 CASP3 APAF1 TNFSF10 XIAP PSMC6 FADD BAK1 CYCS PSMB8 RIPK1 FAS PRKCD APC LMNB1 PSMD3 PSMA5 PSMD7 BAX PSMD13 PSMB10 PSMD10 BIRC2 TFDP1 CASP8 GAS2 PSMD11 PSMA3 DNM1L PSMC4 TNF PSMD8 STK24 APPL1 CASP10 BCAP31 PSMA6 H1F0 BAD DSG1 PSMF1 PSMD5 PSMB3 TJP1 YWHAB BCL2L11 PSMA1 DIABLO PSMA4 BMX TNFRSF10B BID PSMD9 DYNLL1 DAPK2 PSMC3 PSMA2 DFFB PSMA7 CASP9 PSMD1 PSMB7 BCL2L1 UNC5B HIST1H1D PSMD2 PSMB5 PSME4 PSMD14 MAGED1 CFLAR PSMB6 PSME2 PSMD12 PSMB1 PSMD6 KPNA1 PSME1 HMGB2 CTNNB1 PSMB4 PSMB9 PMAIP1 GZMB PTK2 PSMB2 TNFRSF1A MAPK8 PSMC2 TRAF2 PSMC5 LMNA HMGB1 DSG3 FNTA PSMD4 PSMC1 TP53 RPS27A PLEC PAK2 PPP3R1 PKP1 KPNB1 DCC NMT1 FASLG HIST1H1B TRADD UBA52 AKT1 HIST1H1A DFFA SPTAN1 E2F1 HIST1H1E ROCK1 ACIN1 ADD1 DAPK3 SATB1 BBC3 GSN BCL2 PRKCQ DAPK1 VIM MAPT ARHGAP10	0.086267	DOWN
MAHAJAN_RESPONSE_TO_IL1A_UP	LMOD1 PCP4 APOD RHOB HBEGF DUSP1 PTPRZ1 ITGA1 CXCL2 TNFAIP2 EFS FSTL3 IL7R ERG IL6 GFRA2 KCNA1 MYC MAP2 LTC4S CCL20 BEST1 COL7A1 ADORA2A PTP4A3 IL6ST CHST7 KRT32 AR MERTK LRMP PIM2 TFPI2 IL1B SERPINB4 CCNT1 KDR STAT4 CSF2 FLT1 NFRKB ISG20 TMPRSS6 RAB11B CXCL3 CCL5 SERPINB2 MMP12 AKAP8L ALB NRCAM IL15RA CCL8 RB1 SPTBN1 STAT1 CXCL5 TNP2 PDGFRA IL1A MAFK SSTR2 B4GALT1 THBS1 SOD2 IFIT2 RIPK1 SECTM1 BAK1 PPARA NEDD9 TRIM25 ACVR1B CDX2 MAP3K13 AKR7A3 MYB SLC16A1 SDC1 OASL	0.0867356	UP
APRELIKOVA_BRCA1_TARGETS	PEG3 TAGLN NEFL ACTA2 TUBA1A QKI FGFR1 ACTC1 VIM ANXA5 TFAP2C ACTA1 TPM1 WARS DDX24 SPTAN1 TCEA1 RPA2 WNT3 PSMC1 HSP90AA1 PSMC2 DDX3X DDX1 CKB EIF2S1 EIF3C SARS DNAJA1 EPRS DDX21 SFN ARF1 APP ATP6AP1 PDIA3 ROCK2 DLG1 ID3 STAM RIT1 NUMB LXN KRT8 FGFBP1 CA2 ANXA3 HMGA2	0.0869496	UP
HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP	THBS2 THBD FILIP1L TGFBR3 NR4A3 BNC2 MCAM RAB31 SERPINF1 HOXB2 CHST11 TYRP1 PTPRM IFI16 LCP1 ARHGDIB IFI44 ST3GAL5 SSBP2 IL6 CD3D SH2D1A PRKD3 COL5A1 GYG2 CRLF1 MAF N4BP2L1 SGK1 TIMP2 FOLH1 NRG1 DDIT3 DCT CGA USP4 BTRC TYR PIK3R1 NR1H2 GABBR2 LPAR6 RASGRF1 ASNS CDC42EP2 PLA2G15 MLANA SLC6A8 NIPAL3 MIF HIST2H2BE IL1RAP EPAS1 PLA2R1 VHL IGF1R PRSS23 WRN KLRC3 SLCO4C1 TMEM50B PPP2R3A MARCKS VLDLR NPAS2 HMOX1 WSCD1 MYB IQGAP2 AGT CASP7 PTPN3 PDZK1IP1 ERBB3	0.0871683	UP
MCBRYAN_PUBERTAL_BREAST_6_7WK_DN	ACTG2 CNN1 TAGLN SFRP1 TNC IL33 MYH11 APOD EGR2 ACTA2 MAL PER3 BCL6 S100A8 PAM TIMP1 PALLD ST6GALNAC5 SLC1A3 DUSP6 AREG MPZ PLA2G7 UPK3A TNFRSF12A UTRN PDLIM4 BPGM ALAS2 NR1D1 VCAN GSTA3 LY6D CCNL2 RPS10 LSM14B HMGB2 CDCA3 IFIT3 MBP MT2A IRAK1 CAP1 PTTG1 SNRNP27 UBE2C F2R TOB2 UNC50 CDK1 TGIF1 KIF22 IFT57 CISD1 SLPI F3 EPS8 MKI67 IGFBP2 CDC20 PLOD2 CCNB1 SFXN1 DSP CA4 SDC1 SLC4A4 UGT8 ACSM3 EHF	0.0872133	UP
KEGG_O_GLYCAN_BIOSYNTHESIS	GALNT3 GALNT4 GALNT12 GCNT3 GALNT7 GCNT1 B4GALT5 C1GALT1C1 GALNT1 GALNT10 C1GALT1 GALNT2 GALNT8 GALNT6 GALNT11 GCNT4 ST3GAL2 ST3GAL1 GALNT14	0.0872844	DOWN
SUBTIL_PROGESTIN_TARGETS	CYR61 ATF3 CDKN1C DUSP1 BNIP3 JUN CEBPD SAP30 CCND1 H1FX MAP3K3 IL6ST AR GM2A HDAC9 ABCC5 TP53BP2 KAT2B POLR2K BCAS2 NME2 GRB2 BCCIP GADD45A SOS1 EGF RPS6KA1 MAP4K5 UCHL5 ECI2 ITGA2 HMGB3 TGFA	0.0873748	UP
REACTOME_PHOSPHOLIPID_METABOLISM	GBA3 ETNK1 SLC44A4 MTM1 ARSE PLD1 PLA2G10 CDS1 PIP5K1B GALC AGPAT5 LPCAT3 INPP4B SGPP1 NEU1 LPCAT4 GLB1 DGAT1 HADHA AGPAT2 CTSA GPD1L PIK3CB CHKA PLA2G12A CHPT1 MTMR2 SGPL1 PLBD1 SPTLC1 CERS6 GBA SMPD1 HADHB MGLL LPIN2 ARF3 HEXB SYNJ2 VAPB SMPD3 OCRL INPP5J MBOAT7 OSBP SYNJ1 PIK3C3 SPTLC2 AGPAT3 SPHK2 SACM1L PIK3C2B VAPA PCYT2 CEPT1 SMPD2 MTMR4 MBOAT2 PTEN MTMR3 ARF1 PIK3C2G SLC44A1 LPGAT1 PCYT1A MTMR6 PIK3C2A GNPAT PLA2G2A GLA GAL3ST1 HEXA FIG4 PGS1 ASAH1 CERK KDSR PI4KA INPP5K PLA2G2F COL4A3BP CERS2 UGCG CDIPT MTMR1 ARSF PLA2G1B ARSA MTMR14 PIK3R2 PTDSS1 PTDSS2 CDS2 PSAP CHKB PIK3R5 PLA2G3 PIK3R4 PLA2G6 PI4KB NEU3 AGPAT1 STS CHAT PNPLA2 PI4K2A VAC14 PIK3R1 CSNK1G2 PEMT PLA2G2E TAZ ARSB NEU2 PLD2 PLA2G4A ETNK2 INPPL1 PITPNB GPD1 PIKFYVE PIK3CA SMPD4 INPP5E GM2A PCYT1B PLD3 SPHK1 MTMR7 ACHE PIK3R3 LPIN1 PNPLA3 AGPAT4 PIP5K1C PLA2G2D PIK3CG PIP4K2B ARSJ SGMS1 CERS4 PLA2G4C PIK3CD DEGS1 PIP4K2A PLA2G16 PLA2G5 LPCAT1 PRKD1	0.0878695	DOWN
REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT	CHEK1 PSMC6 PSMB8 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 PSMC4 CHEK2 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 RPS27A UBA52 CDC25A ATM	0.0879788	DOWN
GAVIN_FOXP3_TARGETS_CLUSTER_T4	FAM129A GUCY1A3 STON1 SYT11 DENND5A NRP1 PENK PLA2G16 TIAM1 CD48 SH3BP5 BTG2 TNFRSF9 CD44 INPP5F MYC LRIG1 SH3BGRL IL2RA IRF4 RORA NUCB2 CTLA4 AHNAK ODC1 IL2RB GLTSCR2 ATP10D FOXP3 SEMA4A STAT4 MTHFS RRAGD NOD1 GPX4 ITGB8 STX11 CD38 ITGB1 PSMD4 DRG1 P2RX7 IKZF2 WLS RNH1 ITGAE KARS SYNGR2 ITGAV IGF1R HIPK1 YWHAQ ANKRD17 ARF1 PSMB3 XBP1 TIMM10 SMU1 HINT1 SOCS2 PSMD8 METTL17 GLUD1 NRIP1 CAPG NT5E BMPR2 PLSCR1 ENDOD1 CYFIP1 ADSS PLEKHB2 ITGA6 AHCY SMPDL3A IL1R2	0.0880177	UP
KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS_AND_CYCLIC_RGD	CCL11 BCL6 IL10RA CCL22 CCR1 CCR2 CCR4 CD40LG CXCR2 CCR5 IL2RB LTA IL13 CCR9 IL10 CXCL9 IL36RN CCR8 CXCR1 IFNG CXCL11	0.0881038	UP
BORLAK_LIVER_CANCER_EGF_UP	FOS EGR1 BEX1 ATF3 NID1 LPL SPP1 AEBP1 COL4A1 CPE JUNB BTG2 ALCAM LTB CCND1 FGL2 RBP1 SERPINE1 BTG3 TLR6 S100A11 RAB3D SLC7A7 EPS15 LY6D CIDEA TWF2 RRM2 CD63 PDGFA ETS2 IGFBP1 SERPINB6 ID1 CDK1 ANXA2 TGIF1 BLNK PLSCR1 RBM3 ELF3 DDR1 MKI67 SCD KRT18 KRT8 CCNB1 TFF3 CLDN7 CA2 ECT2 TGFA VIL1	0.088166	UP
MIKKELSEN_IPS_WITH_HCP_H3K27ME3	NRN1 IGF2 PHOX2B EREG SLITRK3 IL10RA HOXB2 NTM NR2F2 CDH11 ZNF536 PCDH11X MYCBP2 TMEM59L PRDM8 TBX5 CRLF1 HOXC8 HOXD10 TFAP2B PAPPA ACHE HOXB1 HBZ TBX4 FOXL1 ZMYND10 AVP HPSE2 WNT1 SORCS3 CACNG2 NR2E1 FGF12 CALB1 CACNA1G RPH3A ALOX15 MPPED1 HOXA3 DUOX2 KCNIP1 HOXC6 PCDHA2 HOXB8 LBX1 HOXB3 SLC25A31 TDRD1 HOXC10 GFI1 CACNA1E FAM155A INSRR SIX3 HOXA11 ACTL6B TAF7L USP18 HBQ1 PRDM13 HOXA2 KCNS1 HTR2C NFIX NPY5R TEX12 SLC6A4 PYY HOXB5 CA10 GRM8 VSNL1 HOXD4 HOXB7 HOXB6	0.0884278	UP
ZAIDI_OSTEOBLAST_TRANSCRIPTION_FACTORS	FOS JUN NFATC1 RUNX2 JUND MSX2 ATF4 DLX5 MSX1 CTNNB1 TXLNG FOSL2	0.0891014	UP
SUNG_METASTASIS_STROMA_UP	PTGS2 THBS2 TIMP3 TMEM47 TNC LARP6 FHL1 FBLN2 COL5A2 JUNB THY1 SPARC CD81 SVEP1 ALCAM CDH6 PROS1 TUSC3 CRABP2 DUSP6 CDC42EP3 LMO4 IFI6 COL5A1 HSPG2 ETV5 RFX5 COL3A1 MAP3K8 ALOX5 PLK2 PLOD1 CLDN11 PRRC2B SNAI2 DCBLD2 AGRN FZD8 EIF2B3 FURIN RARRES3 MGAT3 PTPRS VCAN SSX2IP GAA PPIB DKK1 BNIP3L EDEM1 RAF1 CKB CNN3 SEC24D ALDH3B2 P4HA1 PINK1 SOCS5 PRRG2 CALR CD59 TRIO KRT34 PDIA5 SEC13 HEXIM1 SNX1 U2AF2 ASS1 VMP1 GSPT1 SPSB1 STK38L CTDSP2 SDC4 SEL1L3 ADAM10 TKT CD55 XYLT1 CLIP2 DHRS1 FABP5 CD46 EIF1AY AKR1C1 EPS8 MAPK1 SCD ANXA4 HMGCS1 KCNK1 PLOD2 GOLM1 HIST1H2AC SLC16A1 PSD3	0.0892204	UP
VERHAAK_GLIOBLASTOMA_PRONEURAL	GPM6A MLLT11 REEP1 BEX1 FHOD3 FXYD6 ZEB2 NCAM1 SCN3A DPP6 CAMSAP2 AMOTL2 WASF1 TMEFF1 NRXN1 STMN4 FAM110B MPPED2 MAPT NRXN2 DBN1 ALCAM ZNF804A RAB33A TTYH1 PAK3 FLRT1 CSNK1E RUFY3 DPF1 PCDH11X DNM3 SOX11 CRMP1 TMSB15A KIF21B MAP2 C1QL1 BCL7A CNTN1 CXXC4 RBPJ CDK5R1 C1orf61 ATAD5 DUSP26 ZNF510 ATP1A3 CLASP2 SATB1 CLGN SCG3 KLRK1 PPM1E EPHB1 SRGAP3 ZC4H2 SEC61A2 CDC25A SOX2 IL1RAPL1 ATAT1 PODXL2 CSPG5 SORCS3 SOX10 SLCO5A1 GRIA2 CELF3 LRRTM4 NKAIN1 MYT1 SEZ6L DCX ARHGAP33 GSTA4 DGKI DPYSL4 BCOR GRID2 MAST1 NLGN3 STMN1 ZNF248 ZNF286A DLL3 ARHGEF9 NOL4 BCAN TMCC1 OLIG2 PDE10A MATR3 ASCL1 MMP16 GPR17 RNFT2 GNG4 MTSS1 ACTR1A KAT7 ZNF821 GABRA3 PFN2 P2RX7 MCM10 KDM1A HRASLS SPTBN2 LRP6 TTC3 MARCKSL1 RAP2A VAX2 NR0B1 TOP2B E2F3 LOC81691 VEZF1 LPAR4 EPB41 CDKN1B CKB RALGPS2 NCALD HDAC2 PAFAH1B3 FBXO21 KLRC4 CHD7 CBX1 RAD21 YPEL1 CRB1 HOXD3 PURG ICK GADD45G ZNF184 PELI1 MMP15 ZNF711 NKX2-2 CA10 PCDH11Y KLRC3 DCAF7 TOPBP1 GSK3B TSPAN3 MARCKS SOX4 CDC7 FGF9 TAF5 CASK HN1 PHLPP1 PPM1D C1orf106 PLCB4 HMGB3 RALGPS1 MYO10 FERMT1 ABAT MYB SLC1A1 ERBB3 TOX3	0.0896665	UP
REACTOME_PYRUVATE_METABOLISM	BSG SLC16A1 DLAT PDK3 PDHX DLD PDHA1 PDK2 SLC16A3 LDHA PDK1 PDPR PDHB PDK4 SLC16A8 LDHB PDP1	0.089773	DOWN
MORI_MATURE_B_LYMPHOCYTE_DN	SLC16A1 MYB NEK2 CDC25C ENPEP CCNB1 TXN LXN UCK2 CCNB2 LGALS9 PLIN2 DHFR PLA2G12A LITAF EZH2 CAPN2 TAX1BP3 CKS1B PREP CYCS CDKN3 LMNB1 SOX4 MARCKS PGLS KIF2C NDUFC1 COX7A2 BRCA1 PSMD8 IDH2 PRDX4 HMGA1 UFC1 NCBP2 PAFAH1B3 RRM2 EWSR1 SNRPC H2AFV HMGB2 SNRPB SMARCA4 RAG2 DNTT CDC45 PSMC1 MCM5 RNASEH2B MPP1 RAG1 STMN1 MYL4 DGCR6 NUDT1 CCND3 NOTCH1 LRMP GFRA1 MTHFD2 PRPS1 IL7R GAS7 CD93 VPREB3 RGS2	0.0899665	DOWN
YEMELYANOV_GR_TARGETS_DN	EGR1 JUN SRF EPHB1 GATA4 PAX6 STAT1 ATF2 SMAD3 EBP	0.0900221	UP
LIN_NPAS4_TARGETS_DN	EGR1 EGR3 ELAVL4 EGR2 SV2B LMO2 NPTX1 RGS4 TESC HSD11B1 IER2 KCNA1 DUSP4 NPTX2 SLC4A7 CRTAC1 ARC BDNF PXDN ARPP21 CRHBP CPNE7 HPCA KLF9 SORCS3 OSGIN2 KCNIP2 FAM131A GPR4 EGR4 VGF GPR22 DICER1 DCTN6 NMD3 KCNA4 ETV3 WDR77 GUK1 SLC12A3 GADD45G KIF18A FHL2 IER5 SKP2 SEPT8 RAB40B OPN3 ITPKA GLCE	0.090091	UP
BIOCARTA_CDMAC_PATHWAY	FOS PLCB1 JUN PRKCB MYC PRKCA NFKBIA CUZD1 RELA HRAS RAF1 MAP2K1 NFKB1 TNF MAPK3 MAPK1	0.0901111	UP
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN	RTN1 SRPX PTGER3 S100B KLF2 GPNMB DFNA5 F13A1 NRP1 MMP9 OLFML2B SERPINF1 RGL1 C1QA CXCL2 CCL18 RASGRP1 DOCK4 PPP2R2B RPS6KA2 C5AR1 TSPAN2 IL7R CCL4 C1QB A2M DAB2 PPBP CXCL1 RASSF4 HS3ST2 PLA2G7 STAB1 TGFBI MAF FJX1 PADI4 MMP8 SGK1 APOE CEBPE MS4A2 SLAMF8 FRMD4A RNASE1 CHIT1 CD1B ACP5 FABP3 HRH4 ACSL6 CST7 GLUL HS3ST1 CHI3L1 TEX15 DEFA4 TLR7 BPI TCN1 CCL23 CLEC5A ACE CXCL3 PCSK5 IL1R1 SLCO2B1 MMP12 RAP1A PDK4 FOLR3 CTSB FCER1A LGALSL FPR3 SLC7A8 CCL7 KCNJ15 TACSTD2 TREM2 CXCL5 S100P CD59 LHFPL2 LGMN SLC38A6 PDE4DIP ID3 NPL BLNK CEACAM8 FUCA1 CD9 ME1 CD24 CEACAM6 SLPI ST14 PID1 MAOA RIT1 CCL13 DACH1 MMP1 MREG PADI2 EMP1 MAPK13 IL1R2 ANXA3 RARRES1 CORO2A	0.0901525	UP
RAMALHO_STEMNESS_UP	RNFT1 TOM1L1 GCLM PEX7 ELOVL6 UPP1 SUCLG2 ZCCHC10 ALDH7A1 ACADM PAFAH2 MPDU1 BLZF1 YES1 PPP2R1B ITGA6 LIMA1 SEC23A ADAM9 WDR55 YAP1 FCF1 TXNDC9 RRN3 KLHL7 STXBP3 RNF138 CDKN1A RAD23B RPP14 TXNRD1 KRAS DCTPP1 GCSH SMAD1 MED23 PPIC FBXO38 STAM ACAT2 IARS2 TMEM183A MRPL34 CTTN CHD1 UMPS NDUFAF1 PRPSAP1 RABGGTB EIF3J LAPTM4B ROCK2 ZC3H14 NDUFAB1 GAS2 PSMD11 SEC23IP USP10 NDUFAF4 GAB1 SOCS2 LSG1 F2R MRPS10 DNAJB6 UBE2D2 ZZZ3 KIF2A SMAD2 YWHAH HSPA4 PDCD2 TJP1 IMPAD1 YWHAB MAP4K3 PPP1R2 ANKRD17 GFER MRPL3 TARS2 ARCN1 RASA1 MSH2 FKBP9 BACH1 RYK MRPS2 USP9X TPP2 PTPN2 PPA1 TBC1D15 EPRS EIF4G2 RNF4 SLC7A6 ARIH1 CDK2AP1 PSMD12 UTP20 DDX1 RSRC2 GLO1 ZFX COPS4 GCAT SNRPC RARS2 DTYMK ERCC5 STRN3 FKBP11 XRCC5 ESF1 RPL22 MRPS31 GNB1 TGS1 LAPTM4A MTMR10 COPS7A DICER1 ITGB1 MRPL17 RCL1 CTBP2 PRPF6 MARCH7 PHTF2 DPH5 BYSL IARS PLA2G6 XPO1 SRSF6 CAD GNL2 ZNF281 GARS PCF11 RSL1D1 LSM2 MPHOSPH10 WDR43 EIF4EBP1 INTS5 GSTA4 ZNF639 SRSF3 NOP56 XPOT RCN1 TRIP6 GRWD1 LAS1L MDFI TNPO1 KCNAB3 ZMAT3 SLC38A2 ZMYM4 SLC4A7 MDFIC CCND1 GHR CBR3 KANK3 CRTAP TGIF2 PLS3 PKD2 FHL1	0.0903028	DOWN
OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP	MEST SLC35A2 MELK NDUFS1 PRSS8 SPINT2 SDHB ATP13A3 TNFSF10 CKS2 SRPK1 SLC25A5 PSMC6 CSTB ATP5B FH CKS1B CD9 CYCS CDKN3 SLC35B1 PLSCR1 PRKCD ATP5F1 CTNNA1 ACP1 PRKCI LRPPRC ATP1B3 PTS RALY COX6A1 COPB2 COX7B ATP5C1 GPI CAPG NMI KDELR2 UBXN4 PSMA3 LDHA UBE2V2 MDH1 COPS5 NDUFV2 OAT ARF4 EFR3A DPM1 SNRPD3 ZNF146 SUMO1 MRPL3 TMED10 PRKDC NUP153 YWHAZ CSNK2B TARS HERPUD1 PSMA2 HMGN1 SRSF9 UBA1 RAD21 CBX1 EPRS B2M HNRNPM NUP205 MAP2K1 RAF1 GLO1 SDCBP CKAP5 HMGB2 POLR2K PSMB4 H2AFZ CD47 SSR1 MBTPS1 PSMB2 ADAR YBX1 MAPRE1 HNRNPU SNRPB2 HMGN3 RHEB IARS SRSF4 SUMO2 GNAS RANBP1 CSE1L DDX39A THAP11 NASP CCNE1 DDX5 TCEA1 IFI30 HNRNPD TPM4 CFI TM4SF1 IFIT1 BTG3 RFC4 TUBB PARP1 PTGS1 IFI44 SPP1 MAL	0.090327	DOWN
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_10	BCKDHB CLDN7 RALA YIPF5 PEX13 PEX2 SLC30A5 TM9SF3 CDK2AP2 GCSH DAD1 SAC3D1 ADK TMEM11 ATF1 LDHA FKBP4 VDAC2 CHCHD7 RLN1 UFM1 RRBP1 PSMA4 PRDX1 FKBP2 TMED2 SUMO1 PCNA CANX ARCN1 DYNLL1 COX17 EDF1 BOLA2 RPN2 SEC61A1 SERP1 POLR2F USO1 POLR2L EIF1B CERS2 HNRNPR MRPL40 TIMM23 CCT7 SSRP1 HNRNPA3 CACYBP RANGAP1 SLC1A4 AP4S1 SSB EIF3G GRWD1 SF3A3 DFNA5	0.0903892	DOWN
LEIN_MEDULLA_MARKERS	LYVE1 P2RY14 PMP22 SPP1 FSTL1 ENTPD3 P2RX5 VEGFB PPP2R2B ANXA5 PHLDA3 HLA-DRB1 ABHD8 KCNAB2 RASSF4 MYC ZAK LHX5 MARCH2 PHF20 ESYT1 LDLR ANKRD55 AR CLGN PIKFYVE KCNJ14 HOXC4 EIF5A2 NRG1 P2RX6 WNT8B SLC34A1 FZD8 SLC6A5 SV2C ESRRG KIAA1024 MAFG FNTA GLRA1 KLHL36 CHRNB4 TRIP10 CD151 CCT8 DLK1 CD59 GLRX3 UFC1 PRDX1 TAT SLC17A6 HMGA1 ACBD3 GAS2 ANXA2 TNKS NSDHL ADIPOR2 CAPN1 CROT SLC26A6 PCSK6 SLC6A9 HOXB6	0.0909913	UP
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_UP	IGF2 NCAM1 MEOX1 SLC43A3 ROR2 IGF1 NGFR NAP1L1 CRABP2 HOXD9 EFNB3 MYCN STMN1 SET VCAN NCAM2 PRIM1 ENC1 H2AFZ DDX1 BUB3 HDGF HOXA1 BIRC5 WHSC1 CDK1 HEXB HOXA10 EZH2 HMGA2	0.0918229	UP
LEIN_MIDBRAIN_MARKERS	AMIGO2 PLP1 PRPH PCOLCE2 TSC22D3 PTGDS BNC2 COL15A1 P2RX5 LTBP3 ZFHX4 ITIH3 ZFHX3 CD83 MAGED2 PHLDA3 PCSK1N DNM3 SEMA3F KIAA0930 ANKRD55 GFRA1 ALDOC SLC4A2 CLGN AFAP1 EPHB1 EIF5A2 GLRA3 GPC5 ECE2 GPR1 AGTR2 BAIAP3 GABRQ POU4F1 BCAT1 ITGA10 GLRA1 HAP1 GLRA2 SLC6A3 KLHL1 EN1 CERS2 HTR2C CREBL2 TRAIP DLK1 NSMAF SLC17A6 HMGA1 QDPR TCF7L2 SEMA4G PIGT ENDOD1 ARHGEF40 MTMR2 SLC39A14 DENND1B KCTD9 AGT TTC39A DDC	0.0930208	UP
SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER	GAS1 UCHL1 SFRP1 SGCE BNIP3 FGF2 WISP2 BST2 SRGN AURKC CRLF1 ARC MMP8 CSF3 SPANXC CDC25A KRT17 DAZL CDKN2A PAX6 TKTL1 GAGE2C DDX4 CDC42EP2 TERT MLH1 TP53I11 STAT3 S100A2 GAGE12I MAGEC1 LHX2 S100P HSPA1A DAPK2 CCNA1 NLRP2 IL32 EZR BIK CRIP1 SALL1 ITM2C LIPC F11R CLDN7 CASP5	0.0931138	UP
KLEIN_TARGETS_OF_BCR_ABL1_FUSION	CXCR4 GYPC PAX5 PTPRC CD19 CSF1R CD79A POU2AF1 TNFRSF13B BTK NCF4 ITGAL IL7R MNDA CD40 IKZF1 GATA1 SIGLEC8 IRF4 CSF3R SPIB PML CD33 SEPT9 TCF3 IL3RA RAG1 MZF1 NUP98 IGHMBP2 MPO CD38 RAG2 SLC22A2 CBFA2T2 IGBP1 IRAK1 SYK RUNX1 MLF2 BLNK MYD88 ANPEP PROM1	0.0932943	UP
REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS	SLC38A4 SLC3A1 SLC1A1 SLC36A1 SLC17A5 SLC25A10 SLC16A10 SLC15A2 SLC38A1 SLC17A6 SLC7A9 SLC7A1 SLC5A5 SLC6A20 SLC7A6 SLC1A5 SLC7A8 SLC1A7 SLC7A11 SLC6A14 SLC1A2 SLC7A2 SLC1A6 SLC7A7 SLC1A4 SLC15A1 SLC6A12 SLC38A3 SLC6A6 SLC3A2 SLC6A15 SLC17A1 SLC43A1 SLC17A7 SLC38A2 SLC7A10 SLC1A3 SLC7A5 SLC15A3	0.0933134	DOWN
BIOCARTA_GPCR_PATHWAY	FOS JUN PRKAR2B NFATC1 PRKCB NFATC4 PPP3CC PLCG1 PRKACG PRKCA PPP3CB PRKAR1B PRKAR1A NFATC3 GNAS ELK1 GNB1 HRAS ADCY1 CALM1 RAF1 MAP2K1 CALM3 CALM2 CREB1 PPP3CA GNGT1 GNAQ PRKAR2A MAPK3 PRKACB RPS6KA3 GNAI1	0.093494	UP
DASU_IL6_SIGNALING_SCAR_UP	TNC TMEM158 CLEC3B MOXD1 PBX3 IRS1 DNM1 ZFP36 PPL CIC CDC25B MME MAF LTBP1 PKIG ZFP36L2 AGRN FCHO1 PLEC UBE2S LARP1 SREBF1 CDC42EP4 MGRN1 NT5E ADCY9 ACAP2 TPX2 CCNB1 MYO1D	0.0939073	UP
PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP	NRN1 GPM6B CHODL MYH11 FGF7 EPHA7 VCAM1 SPARCL1 RGS5 IFI44 RGS4 NNAT GJB4 EPHA4 ARC ORAI2 ANO1 CSF1 COL2A1 CELSR3 PAX1 OLR1 KDM5A NFIB C9orf116 CD38 PCSK5 PDK4 IL18RAP IL1RAP TBX3 SEMA3C UNC5C FAS PLSCR1 PARM1 F3 MPZL2 PERP CYP2J2 CLCA1	0.0940072	UP
BIOCARTA_RANMS_PATHWAY	KIF15 AURKA TPX2 KPNA2 RCC1 NUMA1 RANGAP1 RAN RANBP1 KPNB1	0.0943739	DOWN
REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	VIP GNG11 GNB5 GNG3 GNG7 SCT VIPR2 GLP1R GNB3 SCTR GIPR GNAS ADCYAP1 ADCYAP1R1 GLP2R GIP GCGR GNG4 GNB1 GNG13 GHRHR GNB2 GHRH GNGT1 GNG5 VIPR1 GNG12 GCG	0.0945243	UP
LANDIS_ERBB2_BREAST_TUMORS_324_DN	MYL9 SRPX SDPR HSPB8 THBD DPT PRKCDBP ACTA2 CCL11 HTRA1 CXCL12 CLEC3B IGFBP6 ANGPTL2 QKI GPX3 FSTL1 NRP1 SORBS1 COL6A3 PENK COL4A1 COL1A1 FZD4 MFNG VWF LUM HLA-DQA1 MRC1 COL6A1 FADS1 COL18A1 CD34 MAP4 TMEM43 CFP GHR ST3GAL6 GYG1 COL5A1 LYL1 GJA1 CYP4B1 TGFBI PTGES LPIN1 COL3A1 SNRK BNIP2 AHNAK GPD1 ADRB3 DNAJC8 EIF4EBP1 MMP3 PHLDB1 CD36 GAS6 DPEP1 NPC2 H6PD PTPRB LAMB1 MOCS2 FEZ2 MKNK2 TSC22D1 SPTBN1 CD151 RRAGC ACSL1 CDC34 CIDEC NDUFS5 IDH2 S100A6 APLP2 NDUFAB1 BCAT2 PPP2R5A DERL1 UQCR10 NET1 CRIP1 ALAD CYB5A MAN1A1 ATP1B3 KLF4 ADIPOR2 ETFB MARCKS MCCC1 NDUFV1 SCP2 HADHB DHRS7 HEPH PDHA1 NR1H3 SEC23A CYB5B CHPT1 GBE1 IVD MUT DGAT1 SULT1A1 CES3 PDE8A DECR1 PLAC8 SQRDL PGM1 PAPSS2 IDH1 KRT19 GSTZ1 POSTN ALAS1 ACAA2 HADH PHYH GNAI1 EPHX2 AUH BCKDHB GDPD3 CPT2 ABHD5 GPD2	0.0945507	UP
GAVIN_FOXP3_TARGETS_CLUSTER_P7	FOS GUCY1A3 AMIGO2 ANXA1 TMEM158 ITIH5 SNN GZMK DENND5A PRNP JUN EVI2A ACTN1 TNFRSF13B SELP ST3GAL6 IFITM3 AGPAT4 ENO3 IKZF4 GATA1 NTRK3 ECM1 PDLIM4 GSTA4 IL10 FASLG PRF1 LYST DST TLR7 RNF32 QPCT HIPK2 ENC1 AFP USP27X WLS KLRD1 PRG4 TMSB10 HS3ST3B1 ADAMTS6 MTMR3 APP SOCS2 SOSTDC1 LRRC8D NT5E IGF2R RABGAP1L BMPR2 PPIC MSRA CYFIP1 FGD6 MXD1 APOBR MYO1E AHCYL2 MBNL3 MARCH3 ENPP1 EMP1 APPL2 GRAMD3	0.0947175	UP
RICKMAN_HEAD_AND_NECK_CANCER_C	GAL PTGS2 FABP4 REEP1 CALB2 NEFL TNC SERPINA3 VEGFC NEFM PCDH7 RRAD EREG TDO2 AIM2 KLK10 STEAP4 HLA-DRB4 FLRT3 PTHLH ZBED2 ALOX12B CNTN1 KLK5 CNGB1 TFPI2 STEAP1B SERPINB4 SLC6A15 NRG1 KLK7 CALB1 IL24 DEFB4A S100A12 KLK6 OLR1 RGS20 CRCT1 KRT1 CYP27B1 NOS1 MMP13 IL19 IL1RL1 SLC6A14 ABCA12 DKK1 IL36RN KRT75 PSPH POPDC3 TCHH DSC1 CCNA1 MMP28 IL12RB2 CDSN COL4A6 DSG1 AMFR ERAP2 SLC39A2 CXCL11 IL36G SERPINB7 SLCO1B3 SOD2 SLC2A1 MT1M CPT1A CDA GPR39 ARL14 PAQR5 HMGA2 HIST1H4H HOXA9 HSD17B2 HIST1H2BC RNF128 CWH43	0.0947624	UP
IGARASHI_ATF4_TARGETS_DN	ETNK1 POF1B DDC AKR1C3 AGR2 PRKAA1 GALNT4 SOAT1 DSG2 CDS1 PCK2 SFXN1 SUCLG2 SLC22A18 OPN3 CBS ASPH RPS6KA3 GPX2 CEACAM6 SKP2 KCNS3 PEX19 LMNB1 ARRB1 ARPC1A KLF4 RNASE4 PACSIN2 SORL1 CDK19 TRAK1 TRIM37 FZD6 G3BP1 ATP9B GNPTAB NEBL NCKAP1 DENND5B FAM134B S100P CBX1 SEC24D HSPB11 TOMM20 KPNA1 APOH INSL4 KIAA0232 PSAT1 DICER1 PER2 RAP1GAP ASNS EPS15 DDHD2 BCAT1 OSTM1 SLC1A4 RHOBTB1 ATF4 FAM3C LIPA SLC3A2 NAB1 CREB3L2 STC2 WWC3 NOV ST8SIA4 SLC7A5 PHGDH AKT3 LEPR CCL2 ANK2	0.0949734	DOWN
PID_INSULIN_PATHWAY	CAV1 GRB14 IRS1 SORBS1 RHOQ GRB10 INPP5D SH2B2 INS SGK1 PIK3CA PTPN11 AKT2 AKT1 EIF4EBP1 DOK1 EXOC7 PIK3R1 PARD6A PTPN1 F2RL2 RAPGEF1 HRAS CBL FOXO3 TRIP10 SHC1 PDPK1 NCK2 EXOC3 GRB2 EXOC2 PTPRA RASA1 RPS6KB1 SOS1 INSR EXOC5 CRK PRKCZ PRKCI EXOC1 NCK1	0.0951725	UP
SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE	CTH HMGCR CYP51A1 AURKA HK2 CASP3 IDH1 UCK2 SCD AHCY PNP VDAC1 NDRG1 SRPK1 BSPRY ME2 SEPT11 ATP5D MSMO1 SLC31A1 UAP1 CYCS FDFT1 PAICS KRAS ACP1 GRSF1 RIN2 CCNC PGK1 LDHA KTN1 VEGFA HMBS CANX GART TAGLN2 GOLGA7 BMP6 CFLAR EIF2S2 LONP1 SQLE GTF2IRD1 RPP30 PRPF40A TERT SLAMF7 YARS MARS MVK GNPDA1 GARS INSIG1 ELL2 GFOD1 TBC1D8 XPOT SLC3A2 TIMP2 BMI1 IRF4 ALDOC LDLR TNFRSF12A BCL2 ST3GAL1 MYC HIVEP2 OSBPL8 FADS1 PAM CCL3 CAV1	0.0955954	DOWN
HAMAI_APOPTOSIS_VIA_TRAIL_DN	UCHL1 TIMP3 SFRP1 FBLN1 CFD CCL19 KLF2 PLTP FXYD5 EMILIN1 JUN SLC15A3 CCDC85B SPON2 CD19 FOXF2 TMEM45A SLC29A1 LIMD2 KYNU COL6A1 PACSIN3 GDF15 FSTL3 ZNF329 ARAP3 ICAM1 IFITM2 ADRA2C KCNA5 MAPK8IP2 H1FX CDH2 BARX1 ADA S100A3 MYBPC2 ANGPTL4 SERPINH1 ISYNA1 BATF3 IMPDH1 BEGAIN FZD9 TNNT1 NOL3 SPHK1 SLC27A5 VCX2 FHOD1 SH3GL3 ALDOC APOE NMB SNAPC2 NRAP DHRS2 TMEM121 ISG15 GRWD1 PLEKHH3 TNNI3 SCLY GFOD1 TYMP IL24 PGAM2 DEF6 HTR1A TXNIP KCNG1 KLK6 HEYL MDK USE1 SGSH PLAUR FOXB1 ECHDC3 SH3BP1 SLCO4A1 MAGEA3 TSPY1 LRRC14 FZR1 GRIN1 ERF CXCR3 LHPP CACNA1E BLCAP INF2 TERT TSC22D4 UBIAD1 ICAM3 TRIM16 CCKBR HIF1A MEPCE ZNF688 SH3D21 MTA1 GTPBP3 IL4R EPS8L1 SEZ6L2 MAGEA6 SHC1 PRDM13 VASP HIST1H2BB BCL3 SYNGR4 SLC5A6 NLE1 SLC1A5 MAGEC1 MRPL2 CISH TRIM46 PYCR1 TAGLN2 STK16 CDC34 SSTR2 MAGEA1 SMARCD2 CHMP1A POLR3E SRD5A3 CYBA STX6 TRAF4 F12 PCDH11Y SAC3D1 FOXD2 DDAH2 ARRB1 SOX4 RPS6KA1 PHLDA2 NR1H3 ERBB2 MAOA PTPRF TRPM4 EFNA1 SERPINB1 RPP25 TP53I3 STEAP3 GALC HOXB9 PCK2 SLC39A4 VAV3 HIST1H2AE SLC16A5 FZD5	0.095958	UP
VICENT_METASTASIS_UP	SORBS2 THSD7A MXRA7 MCAM SUSD5 SNAP25 COCH TCF4 PRKD3 QPCT TAOK3 MICAL2 AIM1 ABCG2	0.0962591	UP
MUNSHI_MULTIPLE_MYELOMA_UP	FOS CXCR4 AXL ANGPT1 S100A4 LY96 JUN PECAM1 HCLS1 TGFB3 PAK3 LIFR TMC6 PIM2 NFKBIA FLT3LG JUND LDHB PFDN5 FST CSF1 MCL1 DDX18 CSF2 RING1 USF2 FZR1 SUMO4 HAX1 MSI1 ISG20 EPOR RAN CDV3 CD68 NACA TRIM32 TERT IFITM1 RHOD ACVRL1 KPNA4 EEF1A1 VAV2 XRCC5 SSR4 TNFRSF17 UBC FOXK2 PSMB1 PSME2 HSP90B1 HSPA5 RELB CFLAR EIF4G2 CD63 CALM2 UBE2L3 USP22 USP9X CALR PSMA2 CANX GAPDH FKBP2 UBB XBP1 UQCR11 ANXA2 DAD1 KATNB1 FGFR3 ZNF91 CYB561D2 DBI CNNM2 ABCC3 KRT8 GSTM4	0.0963146	UP
REACTOME_SIGNALING_BY_RHO_GTPASES	ARHGAP29 RHOB DLC1 ARHGAP6 ARHGAP15 RHOH RHOQ CHN1 ARHGEF3 TIAM1 ARHGAP10 ARHGAP25 ARHGEF4 ARHGEF6 ARHGDIB ARHGAP22 ARAP3 RAC2 ARHGEF17 A2M SRGAP2 ARHGAP24 STARD8 VAV1 SYDE1 FGD1 GDI1 FAM13B OPHN1 SRGAP3 STARD13 RHOBTB2 ARHGEF2 MYO9B GMIP AKAP13 RHOG ARAP1 RHOBTB1 RAC3 ARHGDIG ARHGAP1 MCF2 ARHGEF9 RASGRF1 RHOT2 ARHGAP19 RHOD RHOT1 PIK3R2 ITSN1 ARHGDIA KALRN FGD2 TIAM2 ARHGAP4 RHOA GDI2 ARHGAP17 ARHGAP35 TRIO RALBP1 OBSCN ARHGAP28 BCR RAC1 ABR ARAP2 ARHGAP11A CDC42 ARHGEF11 SOS1 NET1 ARHGEF18 ARHGEF12 RHOF OCRL ARHGEF16 ARHGAP26 RACGAP1 G3BP2 SOS2 ARHGAP12 FAM13A CHN2 ARHGAP8 VAV3 ARHGAP44 ECT2	0.0967138	UP
LENAOUR_DENDRITIC_CELL_MATURATION_UP	FABP4 NR4A3 DUSP1 SCRN1 ITPKB TRIB2 LPL SPP1 CCR7 PKD2 F13A1 TGM2 CD1C CCDC85B RNASE6 SULT1C2 HLA-DQB1 GATM CCL22 MRC1 GDF15 HLA-DPA1 CD83 CD86 APOC1 HSD11B1 C1QB A2M KCNAB2 CRABP2 IDO1 HLA-DPB1 TNFAIP6 SLA MMD CD74 DUSP5 CR1 STAC INHBA CCL17 ENPP2 FCER2 PFKM CCND2 PTPRO IRF4 APOE RNASE1 RRP1B CD1B FABP3 DNASE1L3 BIRC3 CSF1 ECM1 PDLIM4 LIPA SPTAN1 FCGR2A ALOX15 CD1A GAS6 AES IARS RAP1GAP ST6GAL1 HMGN3 PFKP SHB MMP12 QSOX1 PEBP1 CD59 CCNA1 ITGB5 CITED2 CCNH DPP4 ARF4 OAT SERPINB6 NCAPH CTSC SCARB1 KIAA0100 PCBD1 CYB5A SEMA3C ACOT7 CCNG2 PPIC PRKACB MGLL SOX4 ATP1B1 LGALS3BP FABP5 TFRC CAT NR1H3 SLC11A2 MAOA ABCG1 SPINT2 CCL13 CBS ACAA2 CDH1 CEBPA RARRES1 PPARG TGFA	0.0967488	UP
VANASSE_BCL2_TARGETS_DN	FEZ1 CR2 FN1 GPX3 F13A1 TRPS1 CTSG TUBG2 PLXNC1 MAP4K4 NEDD4 CFP SAMHD1 TCF7 CCR1 COL5A1 MYC BCL2 PLA2G7 PTPN14 CCND2 TRAF1 IL9R PGLYRP1 CD1D LTA DNASE1L3 ABCC1 PTPN22 MYL4 RTEL1 RNF219 PIK3R4 MPO DPH5 LIG3 ID2 USP14 MCOLN3 RBBP9 HERC6 ELL3 DENND2D BID NEBL MFHAS1 MARCKS EXOC1 CD9 MPHOSPH9 CYFIP1 MUT ANXA4 KIF20A AHCYL2 MYB	0.0969164	UP
ZHAN_MULTIPLE_MYELOMA_MS_UP	NAP1L3 TCEAL2 LARP6 MITF JAM3 RAI2 FZD2 SLC22A17 PALLD WWC2 SERPINE2 DTNA MARK1 CLEC11A CLGN PBX1 FZD8 MYRIP TEAD1 SPRY2 PPM1H MAGI1 RNF32 PCSK5 CST3 TRIM58 TMEM176A WHSC1 NRIP1 TMEM176B FGFR3 FAM171A1 LRP12 BACE2 VWA5A RUNDC3B MYO10 DSG2 AGAP1	0.0970732	UP
LE_EGR2_TARGETS_DN	OGN ZBTB16 RTN1 NR4A2 ADIPOQ MYH11 S100B FGF7 MPDZ PMP22 ITPKB MAL LPL EFHD1 PTGDS SCN7A LIMCH1 PEA15 IL16 FADS1 CLDN5 EPHB6 NACC2 FGL2 CHST2 MPZ FGF1 SLCO3A1 SNCG PRX GFRA1 SEMA6C MAPK8IP1 UTRN SEMA3B FUT8 SNCA SLC6A15 SIRT2 PIK3R1 ABCA2 MVD TMEM40 S100A1 EMID1 TIPARP CERS2 SLC1A5 SERPIND1 RNF13 CMTM6 RAP1GDS1 MT3 PCMT1 MBP MT2A CA3 MAST2 PCYT2 ADAM10 TKT CD55 FTH1 SLC2A1 NSDHL LOX EMP2 FDPS CLTB CDKN1A FAAH FDFT1 LSS IDI1 CD9 GLOD4 MSMO1 ME1 CAT MGST3 SULT1A1 TMEM30A NDRG1 ABCB1 HMGCS1 MYO1B KCNK1 SLC25A1 GJB1 ELOVL6 DHCR24 CYP51A1 GNAI1 PCK1 HMGCR MYO1D UGT8 TGFA	0.0971665	UP
RAGHAVACHARI_PLATELET_SPECIFIC_GENES	FHL1 SNN F13A1 HBB WIPF1 RAB31 TUBB2A MYLK PIP4K2A GNG11 RGS10 SPARC PRKAR2B PRKCB NRGN NAP1L1 PPBP DAPP1 PTGS1 MMD MFAP3L TPM1 PTPN12 VCL ODC1 SNCA ITGA2B YPEL5 PF4V1 MPP1 GNAS MAX ITGB3 CCL5 TSC22D1 TUBA4A RYBP RUFY1 HIST2H2BE CXCL5 LEPROT ASAH1 ZNF185 GLA TNFSF4 ITGB5 APP KIF2A PF4 THBS1 RNF11 HIST1H2BK MLH3 EIF2AK1 RABGAP1L CTTN PDLIM1 PGRMC1 PRDX6 TMEM140 RSU1 ENDOD1 TAX1BP3 CTSA PPM1A HIST1H2AC HIST1H3H	0.0976481	UP
KONDO_COLON_CANCER_HCP_WITH_H3K27ME1	CXCR4 HLX MAPKBP1 DKK2 CADM3 PCSK1N LGI2 SIPA1 COL9A1 PLA2G4A RNASET2 EFNA5 TPR TPP2 CCNA1 ACSL3 C1orf27	0.0977558	UP
REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_	CCNA2 CDK7 PSMC6 CKS1B SKP2 PSMB8 CDKN1A CCNE2 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 CCNH PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 CCNA1 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSMD14 SKP1 PSMB6 PSME2 CDKN1B PSMD12 PSMB1 PSMD6 PSME1 RB1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 WEE1 CDK2 PKMYT1 RPS27A MAX CCNE1 UBA52 MNAT1 CUL1 CDC25A MYC	0.0980002	DOWN
BIOCARTA_LECTIN_PATHWAY	C7 C3 C5 C4A C6 C2 MASP1 MASP2 C9 MBL2 C8A	0.0980862	UP
PID_EPO_PATHWAY	STAT5B INPP5D BTK PLCG2 SOCS3 PTPN6 BCL2 PLCG1 EPO STAT5A SH2B3 LYN PTPN11 PIK3R1 TRPC6 TEC EPOR RAPGEF1 RAP1A HRAS MAPK8 CBL VAV2 SHC1 IRS2 JAK2 STAT1 GRB2 BCL2L1 NFKB1 GAB1 CRKL MAPK14 SOS1	0.0981726	UP
BENPORATH_NOS_TARGETS	CTGF THBS2 DPYSL3 SFRP1 FEZ1 TNC SULF1 OLFML3 ZEB2 PRKCDBP TCF7L1 CDK14 OBSL1 ROR1 LAMA4 DPYSL2 FGFR1 SNRPN IFI16 FGF2 HHEX TRIM22 DTNA SGMS1 DUSP6 FZD10 ZFP36L1 NAALAD2 MSC BAMBI PIPOX GJA1 CACNA2D1 KCNN2 LEFTY2 BMP7 ENPP2 TAL1 LRAT POLR3G CDK17 SKIL LRFN3 PRDM14 KANK1 PRR11 SOX2 FOXO1 EXOSC9 KDR FUS REST NUCKS1 ZIC1 RNF24 JARID2 SET MLLT10 PHF8 PNISR RNF219 LHPP SRSF4 KAT6A MAN2C1 ATP6V1G1 HESX1 TCF20 UBR5 GTPBP3 TAF12 STAT3 RPS3A COMMD3 MED12 DKK1 RPS18 POU5F1 URM1 RIC8B DPPA4 ATAD2 KDM3A CCDC94 CSRNP2 TSC22D1 MGEA5 NANOG RAD54B TLE3 KLHL5 VPS52 BUB3 PTPN2 USP7 FBXW11 ICMT ANKRD1 SLC44A1 PARG NEBL B3GALT4 HAS2 RAB5A DHRS3 DUSP12 UFM1 RBM22 H2AFJ UBE2D3 GNPTAB PDCL HMG20A EPHA1 ADD3 ORC1 CDYL SALL1 TALDO1 NFE2L3 PPP2R3A ZIC3 CAPZA2 RIF1 CDC7 BUB1B CPT1A DHDDS TRIM24 FGFR2 PPP2R1B HN1 JUP TBL1XR1 TOP2A GRHL2 CA4 CDC14B SPAG9 TDGF1 KLF5 CA2 KIF15 MTM1 FRAT2	0.0981965	UP
GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_DN	PXMP2 PDZD8 CASP6 LAMP2 PNPLA4 IFT74 APEH RAB4A HSDL2 MAGT1 PRSS2 IMPACT LYPLA1 FABP5 HELLS PLAGL1 CPSF6 GCSH SPAST SMC5 PTPRD IBTK ADK BRCA2 CNOT8 LSM5 TTC37 NUDT2 FAM149B1 PFDN4 TAX1BP1 NUP160 PRKDC ADCK2 ZNF84 SEC61A1 CHPF2 CCT6A THOC7 NUP54 ZFX ARL1 RB1 SMARCA4 TCEB1 EXOSC10 RPL18 SPATA7 RPL36 CAD AGBL5 NOP56 UBA2 NUCB2 ITPR2 CLGN NFYB FLT3 TMSB15A CDH2 NAP1L1 IGFBP7 PHGDH	0.0982118	DOWN
ZHAN_LATE_DIFFERENTIATION_GENES_DN	GPR183 MYBL1 BCL6 RHOH LCK ADA LRMP TCEA1 MARCKSL1 EPHX1 SYK BIK SORL1 KLK1 CKS2	0.0982542	UP
GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP	RGS1 CXCL13 CCL19 PCDH9 JUN CXCL2 ANXA5 CXCL1 CCL20 CRHBP IL1B CXCL3 TRA2B CCL8 CXCL5 TNFSF4 NFAT5 SOD2 CXCL6 ZBTB10 HIST1H2AC EMP1	0.0982738	UP
REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING	FN1 VWF RASGRP1 TLN1 RAPGEF3 RASGRP2 FGB APBB1IP ITGA2B RAPGEF4 AKT1 FGA CSK PTPN1 ITGB3 RAP1A PTK2 SHC1 PDPK1 GRB2 RAP1B FGG SRC SYK SOS1 CRK	0.0983024	UP
REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1	PSMC6 PSMB8 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 PSMB2 PSMC2 PSMC5 PSMD4 PSMC1 TP53 RPS27A UBA52 ATM	0.098475	DOWN
GAVIN_PDE3B_TARGETS	TFPI SYT11 F13A1 TGFB1 LAMC1 ENTPD1 EBI3 NCF4 FGL2 CYBB IL2RA CTLA4 IL10 GZMB SYPL1 HMOX2 NT5E TNFSF10 SYTL2 IL18	0.098553	UP
BIOCARTA_CTL_PATHWAY	ITGB2 ITGAL ICAM1 CD3D CD3E CD247 FASLG PRF1 GZMB B2M CD3G HLA-A FAS	0.0989613	UP
LANDIS_ERBB2_BREAST_TUMORS_65_DN	SRPX SDPR DPT ACTA2 CCL11 HTRA1 CXCL12 GPX3 NRP1 COL6A3 PENK LUM TMEM43 GYG1 PTGES PHLDB1 TSC22D1 APLP2 DERL1 ATP1B3 KLF4 ADIPOR2 MARCKS HEPH CHPT1 PDE8A PGM1 ACAA2 HADH PHYH BCKDHB CPT2 GPD2	0.0992056	UP
BIDUS_METASTASIS_DN	CLU TFPI ARHGAP6 COX7A1 F13A1 PRRX1 GYPC CORO1A RGL1 SPON2 SIRPA ACTN1 TSPAN4 GMFG SASH3 TRPV2 AQP1 ENG HLA-DRA CCR10 GATA2 ITGAL TLR5 ZBTB20 DRAM1 CD34 PHLDA3 KLHL22 MR1 DAB2 MS4A6A FADS3 RASSF4 SLA MARCH2 BIN1 STAB1 PTP4A3 GABARAPL1 CLEC11A CIRBP SELPLG ACACB EHD1 FRMD4A AHR C19orf60 DDX24 TTC17 IRF3 PPFIBP1 AKAP13 DOK1 SLC25A37 NME3 DUOX2 ZBTB17 EP400 SIL1 NR1H2 HP NAGK MAN2B1 PHF20L1 GALNT6 GTF2F1 INO80D PIP ATP8B4 STK11 CTBP2 NBN MUM1 PTK2B CKMT2 TNFRSF1A R3HDM1 N4BP2L2 RND1 KLHL2 GSDMD ISOC2 EIF1B HEMK1 CFLAR C19orf24 PSME4 CHPF2 TULP4 PLEKHA2 ZNF45 BRMS1 B4GALT1 SYK FAM3A STK17B RAB4B SIDT2 TOB2 RASSF7 ZSCAN16 ZCCHC6 METTL7A PDE4DIP NPL TMEM50B RIN2 BRWD1 SECISBP2 PDK2 PGAP3 PARM1 CPPED1 RNASEL SLC25A20 TFDP2 MKKS NUDT6 MVP ANO10 SEMA5A APOL6 VWA5A PRPF18 TBC1D8B ACADS TMC5	0.0997191	UP
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN	AHNAK2 MFAP5 C7 KRT24 DNAJC6 PLP1 NNMT CR2 TGFBR3 MAP1B BACH2 SERPINA3 MYBL1 MS4A1 RRAD ST8SIA1 TCL1A CHI3L2 S100A8 TPD52L1 PROS1 ITGAL ST6GALNAC5 CD72 PRKCB PDPN CRABP2 SLC26A4 MAP2 MSLN ICAM4 MFAP3L LAMA1 ACSS3 MMP7 GSTA1 SLC6A13 S100A9 ACACB S100A7 BICD1 SERPINB4 SLC6A15 DNASE1L3 FZD8 GFOD1 NTS CUL9 SPRR1A SPRR3 ARSD FBXO2 DCX S100A12 MAGEA4 KRT23 MAGEA3 SERPINB3 GRIN2A GABRP CLCA2 TRPM8 SLC6A14 ABCA12 PRR4 UPK1B C19orf33 PDK4 TMPRSS3 ABI3BP ART3 TF KRT4 SCEL MAGEA6 GREB1 MAGEA11 CXorf57 MCOLN3 CCL7 KRT7 KRT14 CXCL5 GC PI3 S100P KRT6B ZBTB43 MMP28 AADAC ELF5 CFB IL13RA2 ASS1 UGT2B4 SULT1E1 DOCK5 CXCL6 NPY1R ABCA5 LCN2 SPRR1B CTAG2 RAB40B CEACAM6 SERPINA1 ZNF322 DACH1 SLC4A4 TFCP2L1 PDZK1IP1 PIGR RARRES1 ANPEP NQO1 PROM1 DEFB1 ACSM3 RNF128 OLFM4	0.0998352	UP
IGLESIAS_E2F_TARGETS_DN	DMBT1 HIST1H1C REG3A CEL PRSS2 NNT REG1B MT2A CASP9 GNMT LOR ITIH4 IGF1	0.0998815	DOWN
REACTOME_MITOTIC_PROMETAPHASE	MAD2L1 CENPA ZWINT CDC20 ZWILCH PPP2R1B SPC25 NDC80 BUB1B CENPN KIF2C NUP37 ZW10 SKA1 CDCA8 SEH1L KIF18A PPP2R5A PPP2CB NUP85 BIRC5 PMF1 DSN1 KIF2A PPP2R5E AURKB PPP1CC NUP107 PAFAH1B1 SEC13 SMC1A NUP133 NUP43 CENPM STAG1 SMC3 BUB1 NDEL1 ITGB3BP RAD21 PPP2R1A RANBP2 AHCTF1 BUB3 PPP2CA B9D2 CKAP5 PLK1 ERCC6L KNTC1 NSL1 PPP2R5D CENPQ MIS12 STAG2 INCENP PPP2R5C MAPRE1 RPS27 CENPO RANGAP1 TAOK1 XPO1 CENPT NUDC CENPI PPP2R5B CLASP1 CLIP1 MAD1L1	0.0998868	DOWN
SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM	C5orf30 MAD2L1 AUH SLC16A1 HK2 AFG3L2 TXN IDH3A ACVR1B ATP13A3 RMND5A ADSS UBE2K LYPLA1 GLOD4 FH ISCA1 HSPE1 CYCS NDUFB6 EIF4E ZMPSTE24 HIRA ACP1 G3BP2 PRMT3 PSMG1 TMX1 IARS2 ATP5C1 EI24 TGDS FAM120A HPRT1 RABGGTB ZC3H14 RNF114 USP10 PDIA6 UBE2G1 ALG8 POLE3 FASTKD2 PMPCB SLC25A17 COX11 OAT ZZZ3 TFAM ACTL6A EIF4A3 CHERP APP H2AFY AASDHPPT ZNF330 CCT5 PTGES3 WRN KPNA2 YY1 PFDN4 HSPD1 ITPA TRIAP1 MRPL3 SEC13 SRSF1 TIAL1 NUP153 TARS SRSF8 SERBP1 DCUN1D4 ZC3H15 SERP1 NAE1 CCT8 EPRS EIF3A FBXO21 C12orf29 PSMD14 SNRPF SARS KDSR BUB3 HDAC2 EIF2S1 API5 TOMM20 DDX1 PGAM1 DHX9 NOP16 BTF3 CCT2 COPS2 TCERG1 NUFIP1 SSBP1 DCTD EXOSC8 U2AF1 HNRNPA1 ETF1 IPO5 UBE2N NUP93 FBXO9 CNBP DNAJC2 IARS CBX3 NOLC1 YARS RAN ZBTB11 SMARCC1 NUP98 PNO1 NGDN TFAP4 RANBP1 GNL2 GARS OTUD4 PWP1 ATXN10 EEF1E1 DDX19A DARS ALX1 ANP32B SSB UBA2 XPOT SLC3A2 CYP2A13 LDHB BLMH MNT DDX10 DEAF1 DIMT1 NUP210 MTHFD2 SLC39A6 CEBPB CSNK1E NR2F2 PRPS1	0.0998886	DOWN
SUMI_HNF4A_TARGETS	BDH1 CYP4F3 MEP1A ALDH6A1 ABHD2 NMT2 TNFSF10 FABP1 IL22RA1 UNC93A SLC6A4 LGALS2 AKR1D1 DIO1 CYP19A1 SLCO2B1 BHMT SOAT2 ZNF22 SLC47A1 ATP6V0E2 SULT1C2 SFXN3	0.0999231	DOWN
HUANG_DASATINIB_RESISTANCE_DN	KIAA1324 PLCH1 PLCB4 SLC25A15 CA12 IGFBP2 ABCG1 TFF1 TPD52 GPD1L CHPT1 ABHD11 SLC35A1 CLDN3 SPIN1 CERS6 BBIP1 TOB1 CLN3 ICA1 PDCD4 EMP2 UBL3 ISOC1 CYB561 CRNKL1 SCARB1 ACSL3 TRIM13 SLC38A1 YME1L1 MYEF2 LUC7L3 C14orf93 VPS37C PRLR CALM1 CBX5 GREB1 TBC1D30 METTL9 SLC1A2 EPB41L5 CDC42SE1 IRX5 EPS15L1 ASCL2 MEGF9 ACSS3 SLC16A6 ABCA3 MAPT TRPS1 SORBS2 RHOB	0.0999347	DOWN
MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN	RFC5 KIF4A KIF11 CEP55 AURKA MELK DTL KIF20A TPX2 SPC25 CDC6 CENPF ENDOD1 CENPN KIF2C KIAA0101 CDCA8 NCAPH HJURP FAM204A MNS1 POLD3 MCM7 MORC4 MTMR1 TOR3A ELAVL1 CDC45 KIF20B DONSON PSMC3IP TRIP13 AQP3 TMSB15A CDKN2C MYBL1 PDLIM3	0.100036	DOWN
IWANAGA_E2F1_TARGETS_INDUCED_BY_SERUM	GGH RAD51AP1 MKI67 MUT MTMR2 PLK4 SLC30A4 HAUS6 GEMIN2 ADK ZMYM2 HMGB2 DNA2 PIAS2 HEY1 MAPRE1 SLC8A1 CEP57 FAM111A CLSPN C17orf53 PSIP1	0.100069	DOWN
LI_WILMS_TUMOR_ANAPLASTIC_UP	CENPA TTK MKI67 CENPF NUSAP1 KIF2C G3BP2 CDK1 NCAPH PCGF3 KPNA2 RFC3 CCNA1 HTT HAT1 CDCA3 RAD54L KPNB1 RFC4	0.100158	DOWN
PIEPOLI_LGI1_TARGETS_UP	FGF13 HLF TIMP3 CTNNA2 FGL2 RYR2 MAF DIRAS3 EPHA5 CST7 MAGEA5 BCL2L11 TNFRSF11B NNT HMGB3	0.100351	UP
REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION	UGT1A9 HMGCS2 PPARG ACOX1 HMGCR CPT2 PPARGC1A AGT ARNTL ALAS1 PEX11A HMGCS1 NPAS2 ACADM TBL1XR1 PLIN2 FABP1 CDK8 MED14 CPT1A TNFRSF21 MED20 PPARA ME1 YAP1 FDFT1 NCOA2 TXNRD1 ESRRA MED23 NCOA6 CCNC MED21 FHL2 SREBF2 MED17 CDK19 NCOR1 RXRA MED7 MED6 EP300 MED9 MED4 MED18 MED24 MED31 APOA2 ANKRD1 MED8 MED25 HDAC3 ACSL1 CLOCK NFYA TIAM2 MED12 TEAD4 TGS1 NCOA3 MED16 CYP4A11 SREBF1 MED13L SULT2A1 CREBBP NR1D1 MED27 NRF1 MED15 CD36 TEAD1 CYP7A1 ABCA1 CYP1A1 NCOA1 MED1 MED22 APOA1 TRIB3 RORA NFYB TEAD3 ANGPTL4 TBL1X ABCB4 GLIPR1 FADS1 G0S2 SMARCD3 WWTR1 CTGF	0.100482	DOWN
TOMLINS_METASTASIS_UP	RAB6B GRK5 DVL3 RHBDF2 CDKAL1 CAMKV EVC RIMS2 NEDD8 FAF1	0.100488	UP
BIOCARTA_MCM_PATHWAY	ORC2 CDC6 ORC5 ORC4 MCM4 CDT1 ORC1 MCM2 ORC6 KITLG MCM7 CDKN1B ORC3 CDK2 MCM6 MCM5 CCNE1 MCM3	0.100701	DOWN
FLOTHO_PEDIATRIC_ALL_THERAPY_RESPONSE_DN	PALMD ZCCHC24 SNN KIAA0922 CNR1 JAKMIP2 ZNF135 INSM1 KLHL11 BAIAP2 EHMT2 CD8B DHX58 POLD1 MRPL28 PDLIM2 TTLL4 CASP8AP2 ANKRD40 TRIM21 ASF1B ESPL1 LMNB1 FBN2 CA12 DDX60	0.101039	UP
VERRECCHIA_RESPONSE_TO_TGFB1_C5	ITGA5 NME4 ITGA4 EPHA2 MMP2 DVL3 ILK SEMA3F FGD1 WNT8B ARHGAP1 SMO MMP11 EFNA5 ITGB8 RHOD ITGB3 TNFRSF1A CTNNB1 CTNNA1 DDR1	0.101124	UP
MCCLUNG_CREB1_TARGETS_UP	FOS CTGF INA MPDZ NEFM CDK14 STMN2 PTGDS SERPINI1 FSTL1 OLFM1 PLS3 BASP1 ADARB1 SST NACC2 TSPAN5 SCN1B CDH13 NOV TRPC4 NR2F1 MEF2C KLF10 SYP BDNF MOBP TUBB3 DIO2 FBXW7 GABRA1 FGF12 FAM3C NEUROD6 STX1A CD99 NEUROD2 SEMA7A STMN1 CADPS BCAT1 ADCYAP1 MMP16 STMN3 C9orf16 CCK NDRG3 FABP7 LMNA GNB1 AQP4 ID2 ASH2L TUBA4A SYT17 SYT2 TBR1 ELAVL2 CERK SERF2 SSTR2 IFT20 UTY GLRX3 SH3GL2 CAP1 H1F0 BZW1 HIVEP1 UQCR11 TMEM160 LAPTM4B OSBPL1A ARF6 NDUFC1 ACOT7 PTPRD HSD17B12 OCEL1 ACYP1 ESRRA IDI1 NPY MGST3 ADCY6 SMAP1 RALA AUH CRYL1 HSPA1B	0.101162	UP
DIRMEIER_LMP1_RESPONSE_LATE_UP	FEZ1 RFTN1 SERPINB9 TUBB2A RUNX3 CCL22 FSCN1 SLC7A5 PIEZO1 TNFRSF1B SWAP70 MDFIC CD44 PLEK CD40 AHDC1 MTHFD2 IRF5 BATF STAT5A LYN TRAF1 SPIB NFKB2 RHOG STIP1 POM121 VOPP1 OTUD4 GARS NBN ETF1 SRRT IL4R HUWE1 TRIP10 RPS28 CARS FASN CFLAR SQSTM1 SLC7A1 ANP32A CSNK1D NFKB1 BZW1 DHCR7 CRIP1 TNIP1 CD58 MARCKS LITAF ATP13A3 SLC20A1 HMOX1	0.101189	UP
VERRECCHIA_RESPONSE_TO_TGFB1_C4	THBS2 TNC COL16A1 RAC2 NOTCH2 MMP17 PAK2 LAMB1 MTA1 RAC1 THBS1 EPHB2 MMP1	0.101209	UP
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP	CRYAB GUCY1A3 CLU TFPI CAV2 RBPMS ZEB2 PPP1R3C FRY AXL PDZRN3 LDB2 CDKN1C CDH5 PMP22 THSD7A SPP1 MITF AMOTL2 ANGPT1 PRNP SERPINF1 TCF21 GPRC5B MYLK OLFML2A PLS3 GNG11 RGL1 COL1A2 IGFBP7 PODXL MXRA8 TPST1 KCTD12 CX3CL1 ALCAM TNFAIP8 LRRC32 TEK CTSH PPL ERG NR3C1 CPVL CEBPD ST3GAL6 PLCG2 DAB2 MAGI2 TGFBR2 IL27RA MATN2 DUSP9 MAF KIFC3 PATZ1 MERTK APOE LYN IFIT1 OXCT1 TBC1D9 AHNAK PLAU ATP10D AGRN KDR FAM3C BPGM KAZN ERBB4 DSTN DST SP100 CRIM1 REEP5 PRCP IL1R1 NCOA3 ALDH4A1 MYOF COL4A5 PDE6B UGCG MYH9 TACSTD2 CREBL2 ITM2B SYNGR2 LEPROT ASAH1 ACSL1 HPN ETS2 HERPUD1 TGOLN2 GADD45A MTMR6 IQGAP1 ATP5L ALDH1A1 VEGFA APOM TRAM2 XBP1 EFR3A CRYZ IQCK PPP2R5A CTDSPL PGRMC2 BLVRB ZNF44 CTSO S100A10 CYB5A RAB22A SEMA3C ELF1 CAST CARD10 FGFR3 SSFA2 PRPS2 ATP1B1 SCP2 FUCA1 ATP1A1 TOB1 CLDN3 MECOM FGF9 TMED5 MSMO1 CRADD KIF13B SLC37A4 PDXK GLUD2 TSPO SDHD VLDLR DYNC2LI1 SLC30A1 SEPHS2 ALDH6A1 GNG12 TRIM2 MAN2A1 PDE8A CA12 ANXA4 ANK3 IL10RB SERINC5 LLGL2 KRT19 ENPEP SMPDL3A CDH1 LAMP2 CDS1 PLS1 CD2AP GNAI1 IQGAP2 PEX7 ZNF124 ANXA3 SLC22A5 FPGT TOM1L1 SLC35A3 IMPA2 AKR1C3 ACSM3	0.101226	UP
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN	NR4A2 CCL2 RHOB TRIB2 GAS7 ZFP36 PTPRC AQP1 CCL4 CCR1 SERPINE1 VASH1 INHBA TNFSF8 NINJ1 SLC4A2 TM4SF1 TRAF1 KDM6B SPTAN1 CACNA1G SLC25A37 HIP1R SLC1A6 CBX3 RARA DYRK1A CD80 PDGFA HMOX1 IL6R CLMN CORO2A	0.101257	UP
DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN	OLFML3 MOXD1 ATP2B4 PDP1 TCF4 SOX11 MSTN IGFBP3 PLK2 ZFP36L2 MYLPF COL11A1 GLRX MARCKS FGF9	0.101297	UP
WOOD_EBV_EBNA1_TARGETS_DN	PTGS2 AKAP12 MFAP5 RGS2 SPOCK1 GPNMB MYLK ALCAM WISP2 CLEC2B MACF1 SLC16A7 ADAP2 SLC39A6 TGFBI SPHK1 TPM1 SLC27A5 SGK1 RAB13 P2RY6 KIF5B ABCE1 IPO7 INSL4 DYNLT3 S100P ACTR2 IQGAP1 TAX1BP1 GNAQ NUDT2 DPM3 KDELR2 CALCOCO2 C4BPB IL13RA1 PSMB8 IDI1 ABCC4 GOLGA4 UGP2 EPB41L3 TSPAN8 ACAA2 MEST MAP7	0.101526	UP
GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP	APOBEC3B XK AMMECR1 HPGDS KIF15 CA2 PRC1 HIST1H1C PCCB TST ELOVL6 KIF11 MINPP1 CEP55 MELK CASP3 DLGAP5 GINS1 TOP2A CA1 ZWINT CHEK1 MPST CDC20 CCNB2 DHFR EZH2 PPIF CENPF SMC2 CDKN3 NUSAP1 CPOX PDLIM1 RACGAP1 PRDX2 KIAA0101 MICAL2 SAC3D1 CDK1 BLVRB TK1 BAZ1A PF4 H2AFX ANKRD27 RRM2 CCL8 ASF1A SPTA1 SERPINB2 CCL5 LMNA CD38 IL1RN RHAG MCM5 CD36 AQP3 ITGA2B HBD PKIG APOE KLF1 TPM1 CLEC11A TFR2 TPSAB1 ICAM4 CCL20 HDC APOC1 SERPINE2 TPSB2 PRKAR2B TUBB2A JUN HBB LEPR DLC1 MYH10 TUBB6	0.102079	DOWN
SENESE_HDAC1_AND_HDAC2_TARGETS_UP	GEM SFRP1 CES1 BCL2A1 RGS2 AP1S2 NAV3 TIE1 LDB2 TMEM158 FN1 SORBS2 DCLK1 C3 G0S2 SCG5 ELK3 TGM2 JAM3 MMP9 PRRX1 COL6A3 EREG GFPT2 MAFF PIP4K2A CHST11 LAPTM5 KYNU OSMR CREM CAMTA1 DOCK4 LTB DKK2 IL7R KLHL21 SRGN RAC2 BICD2 CBFB PDE4D LPXN ZBED2 TGFBR2 TNFAIP3 EXTL3 ST3GAL1 CCL20 HOMER3 GPR3 CHRNA9 WDR6 AFF3 EPHA4 TNFRSF12A IL6ST SH2B3 SPHK1 HIP1 PTPN12 PRDM1 RAB3B CCND2 MYCT1 SUPT6H PHLDA1 ROBO4 EPHB1 FRMD4A SUPT16H PLAU FOSL1 IL1RAPL1 BIRC3 WDYHV1 PDLIM4 PGF STK10 HSF1 POU2F2 MCL1 IL24 NFKB2 OLAH IL11 KISS1 DDX42 CSF2 STIP1 RRAGD ULBP2 PTPRN2 CCNE1 MTAP PLAUR TCN1 PLEC CDV3 DPY19L1 SLC7A2 PHTF2 PRPF6 ITGB1 CXCL3 RPL27A NRIP3 SERPINB2 RAB35 DKK1 TRIM38 DHX9 EIF4G1 PTBP1 CXCL5 KDSR PI3 PSME4 ZC3H12A SIPA1L3 IL1A OTUB2 SEC61A1 BCL2L1 LMAN1 PXN ADAMTS6 IQGAP1 AADAC TNFRSF10B HAS2 RPAP3 HMGA1 TTC37 TFAM IL13RA2 FAM208B PTX3 LARP4 PAPOLA TEX261 SNAP23 USP10 PAX8 SLC16A3 PSTPIP2 MC5R PDE4DIP GLYR1 ATP11B EXOC5 CD55 COPA MCM4 EGFR SPRED2 CTNNA1 PRIM2 TNFRSF11B TMOD1 PPIF TFRC PPARA TMEM8A TWF1 DNAJB14 ZBTB38 GCH1 PLEKHB2 ITGA6 MAOA BMP2 LAMC2 NAMPT SERPINA1 CANT1 WWC1 FKBP1B SMG1 ITPKA MMP1 SLC39A4 IL6R CAPN5 CA2 SLC16A1 GNA13 UEVLD SCYL2	0.102943	UP
KEGG_ARGININE_AND_PROLINE_METABOLISM	AGMAT OTC CKMT1B ASL ALDH18A1 ACY1 ALDH7A1 GOT1 MAOA GLUD2 P4HA2 ALDH3A2 GLS ALDH2 SAT1 AMD1 DAO GLUD1 ARG2 ALDH9A1 ASS1 OAT GOT2 P4HA1 LAP3 PYCR1 CKB SMS ALDH1B1 NOS2 ALDH4A1 CKMT2 PYCRL NOS1 PRODH CPS1 GLS2 GLUL PRODH2 CKM ARG1 NOS3 ODC1 GAMT SRM GATM MAOB	0.103347	DOWN
LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP	GAL CDH19 GPM6B LARP6 S100B PCOLCE2 BCL2A1 FLNA TMEM158 G0S2 PRNP MSN CSPG4 VIM NT5DC2 FOXC1 ICAM1 IL6 CALU CEBPB S100A3 MYC FAM127A ANGPTL4 TNFRSF12A FJX1 COL9A3 ENPP2 CYP26B1 PLOD1 FOXL2 IGF2BP3 COL9A1 PLA2G4A GABRA5 FOXD1 PDIA2 DAZL BCAT1 RTEL1 EYA1 OCA2 ARNTL2 EFNB1 CTSZ TEX12 HAS2 PTX3 KIF14 IGF2BP2 ADM SOD2 GOLT1B TNFRSF11B PLAGL1 HAPLN1 FABP5 ANKH NMT2 BMP2 HRH1 HMOX1 PLOD2 UPP1 FERMT1 GNAI1 IL1R2 SRD5A1 SULT1B1 ADORA2B	0.103572	UP
REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC38A4 SLC3A1 SLC9A2 SLC9A3 SLC4A4 SLC1A1 SLC36A1 SLC17A5 SLC26A2 SLC20A1 SLC12A2 SLC20A2 SLC26A3 SLC26A6 SLC25A10 SLC16A10 SLC9A1 SLC24A1 SLC12A1 SLC12A6 SLC9A8 SLC15A2 SLC38A1 SLC17A6 SLC7A9 SLC24A2 SLC9A6 SLC12A7 SLC7A1 SLC5A5 SLC6A20 SLC7A6 SLC1A5 SLC7A8 SLC34A2 SLC1A7 SLC8A1 SLC7A11 SLC6A14 SLC1A2 SLC4A1 SLC4A5 SLC7A2 SLC1A6 SLC7A7 SLC1A4 SLC15A1 SLC26A1 SLC9A5 SLC6A12 SLC9A7 SLC34A1 SLC38A3 SLC4A8 SLC6A6 SLC3A2 SLC12A4 SLC6A15 SLC17A1 SLC43A1 SLC4A2 SLC12A5 SLC17A7 SLC38A2 SLC4A3 SLC4A7 SLC8A2 SLC26A4 SLC7A10 SLC1A3 SLC7A5 SLC15A3 SLC24A3	0.103706	DOWN
FARMER_BREAST_CANCER_CLUSTER_6	PPM1D RNF43 TACO1 CYB561 DCAF7 POLG2 TRIM37 DHX40 MTMR4 MED13 RPS6KB1 SMARCD2 SUPT4H1 FTSJ3 TUBD1 RAD51C	0.103819	DOWN
CAVARD_LIVER_CANCER_MALIGNANT_VS_BENIGN	UGT1A8 REG1A GGH A1CF SPINK1 REG3A FABP1 SLC25A5 AKR1C1 FTH1 DPP4 PRDX1 HLA-C MYL6 RPL13A ACTB FGA CHI3L1 GLUL CD14 FST DUSP22 FGB UBD CD74 DPYD SPP1 CES1	0.103891	DOWN
NIKOLSKY_BREAST_CANCER_7P15_AMPLICON	HOXA9 HOXA5 HOXA10 HOXA7 HOXA6 HOXA1 HOXA2 HOXA11 HOXA3 HOXA4	0.104166	DOWN
REACTOME_PERK_REGULATED_GENE_EXPRESSION	ATF3 CCL2 NFYB DDIT3 EXOSC9 EXOSC7 EXOSC1 ATF4 EXOSC2 ASNS EXOSC8 DCP2 ATF6 NFYA EIF2S1 HSPA5 KHSRP EXOSC4 EXOSC5 PARN HERPUD1 IGFBP1 DIS3 EIF2AK3	0.104177	UP
HUANG_FOXA2_TARGETS_UP	ACTG2 TUBB2B LHFP RBPMS RGS2 FN1 LAMP3 MAFF PAX5 MCTP1 C5 CLIP4 HOMER1 MAP2 TNFAIP3 TFPI2 NRG1 FST TLE4 GLUL CHAC1 EGR4 ASNS SLC7A11 PSAT1 KCNV1 HLCS KAT2B JAG1 RELB CBLB CADPS2 F2R SOCS2 DCAF17 ATP6V0A2 PLEKHA1 HPGD PCK2 ENPP1 SPAG1 TOX3 CPM	0.104234	UP
REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE	CPT2 PRKAA1 PRKAB2 SLC25A20 CPT1A PRKAB1 CAB39 PRKAG2 PRKAG1 ACSL1 CPT1B STK11 STRADA ACACB CAB39L PRKAA2	0.104586	DOWN
REACTOME_BOTULINUM_NEUROTOXICITY	SYT1 SNAP25 STX2 VAMP1 VAMP2 STX1A STX11 STX16 STX8 STX7 STX10 STX5 SYT2 STX4 STX6 STX12 STX3	0.104637	UP
BOSCO_EPITHELIAL_DIFFERENTIATION_MODULE	PTPN3 CLDN7 TMPRSS4 GPRC5A TSPAN6 CLCA4 TMPRSS2 KRT18 F3 CEACAM5 CEACAM7 CEACAM6 ELF3 MUC4 SPRR1B LCN2 LMO7 EMP2 NDRG2 KRT13 MUC1 ANXA9 TACSTD2 SPINK5 SCEL KRT4 PARD6B TMPRSS11E SERPINB2 TRIM16 TMPRSS11D SLC6A14 MUC16 RHCG GABRP TGM3 DUOX2 KRT17 SPRR3 SPRR1A ECM1 KRT3 KRT16 PSCA TM4SF1 IL36A PPL MAL HSPB8	0.104827	DOWN
KONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3	COL14A1 CR2 NRXN3 CADM1 ST8SIA1 ELMO1 LIMCH1 FBN1 SNAP25 MAPT SLC29A1 ALCAM RASGRP1 CDH6 CRABP1 KCNAB1 SOX12 NFATC4 MARK1 ILK TBX5 LEF1 RARB WDR91 HPSE2 USP48 IRX4 WNT1 HOXD11 GRIA4 TCF3 STIP1 ALOX15 TBX2 RAX ERBB4 NOL4 HOXC5 RHBG SLC1A2 TRIM16 HPS4 CBY1 KDM1A PAX2 ZNF516 FEZF2 LOC81691 TAF7 WBP11 EN2 HNF1B KIAA1109 EML2 IREB2 SMCHD1 XYLT1 TMX1 NPY1R UQCRQ FAM171A1 ISCA1 WNT5A CA12 ERI2 TRIM36 DNAJC22	0.106093	UP
ZHANG_TLX_TARGETS_36HR_UP	CRYAB TUBB2B TNS1 NR4A1 S100B STXBP1 EFHD1 RPRM ITGA5 PDE2A PYGM DNAJB5 S100A4 KCND3 SORBS1 JUN GSTM5 OLFM1 SDC3 CSPG4 SIRPA BTG2 ARNT2 SOD3 TGFB3 CYTIP MAPK10 DDIT4 NNAT CTSF PHLDA3 NACC2 STOM SRGAP2 CLIP4 SCN1B AOX1 AEN VAMP2 FAM127A TGFBR2 CDH13 CADM4 SLC19A2 EXTL3 SP110 PIP5K1C CRLF1 PTP4A3 ENO3 MARK4 GSN TNPO2 GABARAPL1 SLCO3A1 CLCN6 PLEKHF1 SPHK1 KIF1A PLD3 CCND2 PPP2R5B MAPK8IP1 ZMAT3 NTN3 TM4SF1 TIMP2 GRINA WNT7B DUSP3 RALGDS YPEL5 ZFP36L2 CYB5R3 B4GALT2 DDIT3 HIST1H2BL ARHGEF2 CSF1 GTF2I MAPK8IP3 TTLL1 S100A11 MXD4 LFNG AKT2 NFKB2 POU6F1 BTG1 SPEF1 KCNC1 TEF ARMC6 PI4K2A DUSP8 ARHGAP1 DVL2 PNPLA2 OGFR DDX17 CXXC1 ADCYAP1R1 PRMT2 PQLC3 GADD45B SLC7A11 RPL18 CDS2 HIST3H2A MBTPS1 QSOX1 CBX5 TAPBP SETDB1 TSC22D1 CTSE SOX3 FBXO4 NDST1 CD151 F8A1 ADAM15 ACSL1 OTUB2 FTL SLC38A10 SPRY4 OS9 PINK1 PDGFA AK1 TCN2 RAB40C PXN SEL1L KEAP1 EPHX1 GADD45G CITED2 SFT2D2 C14orf159 PARP3 TAP1 KIAA0319L ABHD4 ABCB8 ST6GALNAC4 CCNG1 PTPRE CTDSP2 CYP3A4 RXRA REPIN1 EDEM2 TCTA SAT1 SCAMP5 S100A10 IER5 BAX KLF4 GAB2 CAMKK2 EMP2 POLD4 ARF3 CDKN2B CDKN1A FCGRT PIP4K2C TOB1 BAK1 TAX1BP3 SEPT8 DNM2 GDPD2 CPPED1 DCXR PGPEP1 SCARB2 VWA5A OPN3 KIF1B UPP1 SORT1 MYO10 P2RX4 HIST1H1C GDPD3 HIST1H2BC	0.106187	UP
NAKAMURA_ADIPOGENESIS_EARLY_UP	GAS1 LHFP TGFBR3 NID1 WASF3 ELK3 COL6A3 ZFP36 FYN SST LIFR CEBPD PDE4D CYBRD1 MYC FAM198B PAPPA GM2A NPTXR NFE2 SNAI2 DYM PDE6H FOXO1 PHKG1 USP4 PIK3R1 ABCA1 INSIG1 PDE10A E2F4 GADD45B IL1R1 DKK1 CTNNB1 COL8A1 IRS2 ABL1 C19orf24 USP53 PRSS23 SMARCD2 MT1H MT1G PPP1CA MT1E SOD2 MT1F CHMP1B RIPK1 MT1M MRPS6 IL22RA1 ACVR2A PLIN2 PPP2R1B NFIL3 CCRL2	0.106455	UP
PID_UPA_UPAR_PATHWAY	FN1 ITGA5 MMP9 TGFB1 ITGAM ITGB2 CTSG PDGFRB SERPINE1 FPR1 FGB HGF PLAU MMP3 CTRC ELANE LRP1 PLAUR FGA NCL MMP13 FPR2 ITGB1 ITGB3 MMP12 FPR3 GPLD1 VTN ITGA3 FGG ITGAV ITGB5 SRC PLG RAC1 DOCK1 EGFR CRK PDGFD VLDLR	0.106477	UP
ST_INTEGRIN_SIGNALING_PATHWAY	ITGA7 CAV1 ANGPTL2 AKT3 ITGA5 ITGA1 MYLK FYN ASAP1 ACTN1 ARHGEF6 TLN1 MAPK10 ITGA4 PAK3 ZYX MAPK8IP2 PLCG2 MRAS ILK ITGA9 TERF2IP PLCG1 MAPK8IP1 PIK3CA TNK2 MAP2K7 MAPK8IP3 AKT2 WAS ROCK1 AKT1 CDKN2A CSE1L ITGA8 PAK2 RHO PKLR ITGA10 MAPK8 PTK2 SHC1 VASP ABL1 ARHGEF7 MAP3K11 RAF1 BRAF GRB2 PAK6 ACTR3 ITGA3 ITGB3BP PAK4 ARHGAP35 ACTR2 SRC PTEN P4HB DOCK1 CDC42 EPHB2 MAPK9 MAP2K4 ROCK2 SOS1 CRK TLN2 ARHGAP26 SOS2 PIK3CB ITGA6 MAPK1 GRB7 ITGA2 PAK1 RALA	0.106521	UP
PLASARI_NFIC_TARGETS_BASAL_UP	NRN1 CLU CHODL PPP1R3C RGS5 MPPED2 RGS4 NNAT KCNA5 KCNMB4 WNT5B SEMA4F SNCA GNA14 COL2A1 CACNA1G PAX1 TEX15 GZMH TINAGL1 THSD4 TNFRSF11B PARM1 PERP FOXA1 CLCA1	0.106677	UP
ST_WNT_BETA_CATENIN_PATHWAY	SFRP1 DKK3 AKT3 FSTL1 ANKRD6 DKK2 DACT1 CXXC4 AKT2 AKT1 LRP1 GSK3A CER1 TSHB DVL1 CBY1 PIN1 AXIN1 DKK1 CTNNB1 RPSA CSNK1A1 DKK4 PTPRA WIF1 SENP2 GSK3B FRAT1 APC PSEN1 MVP	0.106744	UP
REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	CCNA2 CDC25C CCNB1 CCNB2 CDK7 CDK1 CCNH CCNA1 PLK1 WEE1 PKMYT1 XPO1 MNAT1 CDC25A CDC25B	0.106891	DOWN
MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_UP	RGS2 FGF7 HBEGF CADM1 SOD3 ARAP3 KCTD15 PARVB CXCL1 PLA2G7 ENO3 TNNT2 SEMA7A CHST1 SERPINB2 SLC14A1 SMS ANKRD1 MRPL15 ANKH PLAC8 F2RL1 HMGA2	0.107061	UP
REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	NRP1 SEMA3A FYN TLN1 RRAS FES PIP5K1C PLXNA3 PLXNA1 RND1 RAC1 PLXNA2 FARP2	0.107075	UP
TENEDINI_MEGAKARYOCYTE_MARKERS	FOS CXCR4 CXCL12 TGFB1 JUN FLI1 GATA2 PDGFB IL6 RASGRP2 IL11RA CBFA2T3 PPBP CXCL1 MYC PDGFC BCL2 GP1BA GATA1 TAL1 STAT5A KIT JUND NFE2 IL1B ITGA2B CCND3 MCL1 IL3RA IL11 GP9 JARID2 MPL CDKN2A CCNE1 TBXA2R MAFG CDK2 IL1R1 ITGB3 CCL5 GP6 STAT3 BCL2L2 JAK2 STAT1 CDKN1B CBFA2T2 CASP9 PDGFA RASA1 VEGFA PF4 BAD CDK1 MAPK14 PIK3C2B CCNE2 CD9 BAK1 MECOM CCNB1 CASP3 IL6R MYB	0.107142	UP
VERHAAK_GLIOBLASTOMA_CLASSICAL	GAS1 LHFP DLC1 ITGA7 MEIS1 MEOX2 PMP22 TRIB2 FZD7 LAMB2 ADAM19 PLA2G5 MAB21L1 LMO2 ZFHX4 TGIF2 FBXO17 RASGRP1 CDH6 NES ANXA5 TGFB3 CREB5 ARAP3 CDH2 ZNF304 PIPOX FZD3 ILK EXTL3 GJA1 ERCC2 SNTA1 CDK6 TEAD3 PTPN14 ACSS3 C19orf66 CD3EAP GNG7 GRIK1 EPHB4 GLI2 GRIK5 LRFN3 JUND NPEPL1 DMWD ZNF671 APBA3 MLC1 SLC12A4 NDP TRIP6 RIN1 POMT2 ZNF8 RGS6 SLC6A11 NR2E1 IRF3 NPAS3 ABCD2 LFNG MEGF8 AKT2 ZNF134 TBX2 KCNF1 CDH4 KLHDC8A MCC CAMK2B BLM SPRY2 DOCK6 SMO KLHL4 GNAS KLHL25 RGS12 RFX2 PRPF31 ITGB8 ZNF446 PCSK5 ACSBG1 KIAA0355 HMG20B HSPBP1 TMED1 SCAMP4 ZNF211 GLG1 ZNF419 TMEM161A DAG1 TMEM147 CALM1 ELOVL2 POFUT1 PRKD2 IRS2 NOS2 ZNF227 TLE2 BTBD2 ZNF235 OSBPL3 JAG1 RBM42 CD151 HS3ST3B1 SHOX2 PTPRA PDGFA ZNF45 SSH3 SIPA1L1 KEAP1 ZNF264 ZNF20 B3GALT1 VPS16 SARS2 LRP5 ACSL3 SOCS2 ARAP2 RBCK1 SEMA6A LRP10 QTRT1 RFXANK EGFR CC2D1A ZNF606 PEPD CLIP2 FGFR3 PLIN3 SLC2A10 NR2F6 GSTK1 EYA2 SEPT11 DENND2A SOX9 SEMA6D SLC6A9 WSCD1 MYO5C ARNTL VAV3 GALNT4 SLC4A4	0.107171	UP
HUMMERICH_SKIN_CANCER_PROGRESSION_UP	FOS THBS2 RGS2 ITGA5 RBMS1 COL5A2 MMP9 VCAM1 COL6A3 COL1A1 JUNB COL1A2 PECAM1 HLA-DQB1 NCF2 SSPN COL18A1 CRABP2 SLC26A4 CD44 DOK2 MYC IFITM3 COL7A1 GABRB3 TNFRSF12A BLMH ADAM8 ARIH2 KRT16 RIN1 SOCS1 APOC2 MMP14 CCNF LGALS7 PRKCSH MMP13 IL1RN GADD45B GCGR ITGB1 STAT3 TNFRSF1A IL4R IL17RA MIF TACSTD2 HSPA5 UBA3 HSPA8 MT2A PLG ENO1 CYBA CUL4A S100A6 ITGB4 CASP8 BCL10 PGK1 OSBPL1A SOD2 THOP1 RCAN1 SMAD1 CDKN1A APC LCN2 CTSD IDE CASP1 MAOA LGALS9 EPCAM SERPINB1 HMOX1 PYCARD KRT19 PERP GLTP	0.107215	UP
SMID_BREAST_CANCER_RELAPSE_IN_LUNG_UP	UCHL1 CSPG4 CLIC4 TTYH1 SLC7A5 ANP32E PRAME KLK7 TNNI2 COL2A1 FOXD1 KRT17 MMP14 KLK6 NMU RYR1 MUC16 KPNA4 PSPH HAPLN1	0.107264	UP
MARTIN_INTERACT_WITH_HDAC	ZBTB16 EDNRA BCL6 CAMK1 ACTN1 RUNX3 SRF PKD1 GATA2 RUNX2 GATA1 PPP1R12A NFKBIA NCOR2 FOXP3 NKX2-5 ATF4 REST CAMTA2 BCOR TP53BP1 UBE2I HIF1A CTBP1 CBX5 KAT5 PPA1 PHB2 ETV6 YWHAQ KPNA2 DNAJB6 ACTN4 NCOR1 MAPK3 NRIP1 RFXANK NR2C1 MARK2 MAPK1 ANKRA2	0.107265	UP
DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP	ANK2 GPM6B TMEM47 MN1 CXCR4 ITPKB MCAM TMEFF1 JUN JAKMIP2 FAM49A PRKAR2B GATM NR2F2 MMD TNFAIP3 TMX4 TBC1D9 ANK1 MYOD1 AQP3 NELL1 MYCN FAM3C DCX HDAC5 ALK POU4F1 STATH EYA1 FAM69A NUP93 PPP1R14B NRCAM MORC4 ZNF395 GADD45A NEBL PELI1 ASS1 NTAN1 ADAM10 TCF7L2 CARHSP1 RWDD3 ACAT2 FGGY ARRB1 CD9 OSTF1 SKP2 FGFR4 PDGFD MET VWA5A BMP5 ABAT VAV3 EPB41L4B	0.107288	UP
BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_DN	TUBB6 DUSP1 MOXD1 VPREB3 F13A1 CHI3L2 SNRPN LTB INPP5D CTSH LST1 DPYD KMO TFEB PIK3R3 VCL PKIG CDKN2A HCK TLR7 RABEP2 KDM4B RRAGC ASAH1 SLC12A8 TOP1 CKAP2 SORL1 CHFR NIPA2 HES1 GALNT10 PLSCR1 BMP2K ATP6V0D1 NEDD9 TNFSF10 DYRK2	0.107296	UP
WIERENGA_STAT5A_TARGETS_GROUP1	CALB2 IGFBP5 CFH SCHIP1 CDKN1C MAP1A TGM2 SAMSN1 HSPA2 PLEKHA4 LTB ST3GAL5 DDIT4 NCS1 CTSH GATA2 PRPS1 PHACTR1 DAPK1 GGT5 HSPA6 DAB2 DUSP5 BBX TULP3 IGFBP4 BATF3 A4GALT SNTA1 ST3GAL4 PIK3IP1 FCER2 DCPS RABGAP1 HBZ PIM1 SEMA6C PHLDA1 CD40LG OSBP2 POU2F1 TRIB3 MEX3D ENPP3 UPK1A SLC9A7 IL3RA SPAG4 PLXNA3 CST7 MIIP FAM131A CD1A SLC25A37 DPYSL4 NOD1 TNFRSF4 NAALADL1 TGFBR1 RHAG GYPB SLC25A4 RAP1GAP MOSPD3 PPFIA4 PFKFB4 ENC1 IL18RAP IL4R DDN CDHR1 ZNF609 SH3BP4 TLE3 PLVAP CTNS CISH TRIM46 CTSZ TRIM58 MUC1 MTHFD1 TARP DHRS3 STK17B FNDC3B ADM UBAC1 SOS1 ARL4A SLC2A10 P4HA2 NDRG1 SLC6A9 NAAA CBS ITGA2 TJP2 MYO10 P2RX4 F2RL1 AMACR	0.107397	UP
MIKKELSEN_MCV6_ICP_WITH_H3K4ME3_AND_H3K27ME3	SYT1 ZEB2 ACTA2 COL1A1 HTR2A IGF1 CALY NOL3 NPY2R SUSD4 COL4A4 UCP1 KCNMB2 ESR2 MCHR1 KCNA4 COL4A3 PLAT RLN1 IGSF3 ANK3 KCNJ2 PTPRR	0.107474	UP
YEGNASUBRAMANIAN_PROSTATE_CANCER	CTH OCLN UGT2B15 DDC SLC44A4 TOX3 SPINK1 ERBB3 HMGN5 TRIM36 AGR2 PBLD TMEM38B CEP76 SLC39A8 ZBTB10 HPGD ALAS1 TMPRSS2 CLDN4 GCNT1 MCCC2 TSPAN8 ALDH6A1 SERPINA1 ABHD2 UGT2B28 SORD PRSS2 DHFR DNAAF2 TRIM68 CTAG2 ALDH3A2 NDC80 CLDN3 FECH KLHL7 KIF23 CENPN KDM6A SMCHD1 MANEA GAS2 MED6 ELF5 TFAM SSX1 RLN1 TARP NEBL BBS4 TPTE ACPP MAGEA1 ECD SUPV3L1 EXOSC4 EIF2S1 GTF2F2 ADO ATAD2 SPDEF CRISP3 LONP1 MAGEA6 ST7 AZGP1 HRASLS ALB NKX3-1 HOXB13 PAGE1 PTPRB NCAM2 SLC25A21 PDE10A SRSF6 MAGEA5 MAGEA3 DONSON SSX3 E2F5 PSMC3IP HPCAL1 BCOR PON1 KLK3 MAGEA4 NXF2 CLCN4 SOHLH2 KRT81 MAGEA12 FOLH1 CALML5 DBT DHRS2 SLC43A1 KLK2 TIMM9 SCG3 RASA4 CLGN PRAME TNNT1 FOLH1B EEF1A2 GPR37 ETV1 COCH ARHGEF26 MYBL1 ARHGAP6 EPHA3 ID4 FGF13 PEG3 GPM6A BCHE	0.107477	DOWN
MORI_PLASMA_CELL_DN	BACH2 MS4A1 ELK3 LMO2 LAPTM5 HLA-DQA1 CD83 CD22 CD40 SRPK3 BCL11A TLR1 SPIB MICAL1 TPM4 LRCH1 ARPC5L CALM2 ANP32A ABLIM1 SMAD1 BMP2K CPM	0.107563	UP
GRADE_COLON_VS_RECTAL_CANCER_UP	PALMD FSTL1 RHOQ EMCN JUNB STX2 CD34 PMP2 ZAK HABP4 DDX50 ENOX2 TEX10 HNRNPC BCL11B RNASEH2B LAGE3 GADD45B ENGASE IL1A RYK CANX INSIG2 ALG5 UMPS ASF1B RPRD1A ZWILCH	0.107904	UP
REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS	INHBB INHBA POMC INHA INHBE LHB PCSK1 CGA TSHB FSHB INHBC	0.108002	UP
VISALA_AGING_LYMPHOCYTE_UP	FILIP1L CYP1B1 CSF1R TAF15 GNLY KAT6A TMSB4X CUX1 LNPEP COIL	0.108017	UP
YANG_BREAST_CANCER_ESR1_UP	CYP2B6 NAT1 TFF3 ABAT INPP4B KRT18 FBP1 CA12 TFF1 SCNN1A SCUBE2 MLPH LRBA XBP1 BBS4 ANXA9 SLC7A8 NUMA1 GREB1 P4HTM KIAA0232 KDM4B ESR1 KCNK15 WWP1 ERBB4 GSTM3 AHNAK TBC1D9 CIRBP APBB2 MAGED2 GATA3 MAPT WFS1	0.108074	DOWN
VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1	THBS2 TNC ITGA5 NME4 COL16A1 ITGA4 RAC2 EPHA2 MMP2 DVL3 ILK IGFBP4 SEMA3F EPHB4 FGD1 NOTCH2 WNT8B ARHGAP1 MMP17 SMO PAK2 MMP11 EFNA5 ITGB8 RHOD ITGB3 LAMB1 MTA1 TNFRSF1A CTNNB1 COL8A1 RAC1 THBS1 EPHB2 CTNNA1 DDR1 NEO1 MMP1 DSP	0.108911	UP
LEIN_CEREBELLUM_MARKERS	CALB2 DMD CASQ2 TNC FAM107A HBEGF KANK2 IL16 PTPRM PLXDC1 ERC1 COL18A1 LHX1 PAQR6 LHX5 NPR1 GDF10 CRTAM KIT TRIM62 PREX2 ETV4 NHLH1 NTN1 FBXO24 ARAP1 ZIC1 BTG1 GABRA6 MCC LRCH1 H6PD GPR63 RHOD PHKA1 GNG13 FEZ2 LIG1 CEP72 CHD7 EN2 ICMT AMOT PQLC1 DHRS3 TRAF6 MMP24 DNAJC3 PEPD ARHGAP5 RIF1 SYNE2 CA7 PKP3 TJP2 TST NEK2 EXPH5 SLC9A3	0.108971	UP
LIAO_HAVE_SOX4_BINDING_SITES	FHOD3 NAV3 NRP1 GPRC5B PAM POU2AF1 SERPINE2 HSPBAP1 MAP4 GYG1 PTPN14 HUNK VCAN HIC2 PFKFB4 GNG4 LAMB1 UBAP2L RBM10 DKK1 UBAP2 SMG5 VGLL4 MYEF2 INTS8 CTSC CHFR NEIL3 SEMA3C SLC2A1 CREB3L1 ALDH18A1 AKR1B10	0.109084	UP
REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION	HIST1H2BC HIST1H4H HIST1H3H HIST1H3D HIST1H2AE HIST1H2BH HIST1H2AC HIST1H2BD HIST1H2BG TFB2M CDK7 HIST1H2BE HIST1H2BI HIST1H2BF SNAPC3 RRN3 HIST1H3E GTF2H2 HIST1H2AJ HIST1H2BM HIST1H4K GTF2H1 MBD2 HIST1H4B HIST1H3A MAPK3 HIST1H3F HIST1H2BK HIST1H4J HIST1H4D GTF3C3 POLR2E BRF2 POLR2H HIST1H2AD GTF3C2 HIST2H2AA3 ERCC6 HIST1H4F POLR3B TFAM CCNH GTF3C5 POLR3E HIST1H3B POLRMT TBP H3F3A POLR1C H2AFX HIST1H4C TAF1A HIST1H2BO HIST1H4L POLR2F POLR1D HIST2H4A HIST1H4A HIST2H2BE POLR2L HIST1H3G GTF2H4 HIST1H2BB POLR2K GTF3C4 HIST1H2BJ H2AFZ KAT2B HIST1H4E POLR3K HIST1H4I ERCC3 HIST1H2AB CBX3 NFIB HIST1H3I LZTS1 HIST1H3C H3F3B ZNF143 SNAPC4 MNAT1 SNAPC5 GTF2H3 POLR3C POLR3F POLR3D SSB TAF1B HIST1H2BN UBTF HIST1H2BL HIST1H3J BRF1 POU2F1 EHMT2 SNAPC2 SNAPC1 TAF1C ERCC2 POLR1B PTRF	0.109095	DOWN
YANG_BREAST_CANCER_ESR1_LASER_UP	AGR2 GSTZ1 DACH1 HMGCL IVD RAB17 OBFC1 CPT1A CERS6 CHMP2A COQ7 DNAJC17 FRAT1 GOLGA1 ALAD KIAA0319L RAB26 SIRT3 UGCG SIGIRR SNRNP35 KAT6B GTF3C1 MSX2 MOAP1 IFT46 AR PATZ1 STK32B APBB2 EVL	0.10982	DOWN
DUNNE_TARGETS_OF_AML1_MTG8_FUSION_DN	RUNX1T1 ELK3 SAMSN1 IFI16 BAALC CD34 SLC2A3 DUSP6 MEF2C EDIL3 ECM1 ADAM12 MTSS1 CKB RANBP2 ID1 FOSL2 DEPTOR TSPAN7	0.109834	UP
REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE	PSMC6 PSMB8 CDKN1A CCNE2 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 PSMB6 PSME2 CDKN1B PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 PSMB2 MDM2 PSMC2 PSMC5 PSMD4 PSMC1 TP53 CDK2 RPS27A CCNE1 UBA52 ATM	0.109866	DOWN
NIKOLSKY_BREAST_CANCER_12Q13_Q21_AMPLICON	PTPRR CPM AVIL LGR5 TSPAN8 DYRK2 CPSF6 YEATS4 CTDSP2 ZFC3H1 NUP107 CAND1 GNS IFNG SLC35E3 TSPAN31 TSFM OS9 METTL21B RAP1B CCT2 CNOT2 MDM2 IL22 PTPRB FRS2 TMEM19 TBK1 LYZ CYP27B1 METTL1 IL26 CDK4 XPOT AGAP2 KCNMB4 MDM1	0.110498	DOWN
DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP	ANK2 GPM6B TMEM47 SULF1 KCNN3 MN1 MCAM TMEFF1 PAX5 JAKMIP2 ARL4C PRKAR2B COL18A1 TNFAIP3 TMX4 SGK1 PRKCA TBC1D9 MYOD1 NELL1 MYCN DCX HDAC5 ALK RASL10A POU4F1 PSEN2 PPP1R14B IL4R NRCAM MORC4 IRS2 MAP1LC3B GADD45A NEBL TRAM2 TNS3 ASS1 INPP1 ADAM10 TCF7L2 FMR1 ARRB1 KCNS3 CD9 SKP2 FGFR4 WSB2 PON2 SPATS2L MET VWA5A BMP5 ABAT MARCH3 PBK	0.111048	UP
KEGG_LINOLEIC_ACID_METABOLISM	AKR1B10 CYP2C18 CYP2J2 CYP2C9 PLA2G10 PLA2G12A CYP3A5 CYP3A43 CYP3A4 CYP3A7 PLA2G2A CYP2C8 PLA2G2F PLA2G1B PLA2G3 CYP2C19 PLA2G6 CYP2E1 CYP1A2 ALOX15 PLA2G2E PLA2G4A JMJD7-PLA2G4B PLA2G2D PLA2G5	0.111092	DOWN
MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_8	A1CF CALML4 HNMT HELLS SOS2 MTDH RBBP4 TMEM80 ZNF148 CREM	0.111102	DOWN
PID_EPHRINB_REV_PATHWAY	CXCR4 DNM1 TIAM1 FYN PTPN13 LCK BLK FGR FGB EPHB4 LYN PIK3CA EPHB1 ITGA2B PIK3R1 HCK FGA RGS3 ITGB3 MAPK8 NCK2 EFNB1 FGG MAP3K7 SRC RAC1 EPHB2 MAP2K4 EFNB2 YES1	0.111283	UP
FARMER_BREAST_CANCER_CLUSTER_7	SLC35A3 TRIM36 CDH1 ECI2 SCD TMEM135 ESRP2 TMEM41B BLVRB ALDH3B2 FASN RND1 SREBF1 MSX2 IRX5 DHRS2 AR GHR ALCAM	0.111292	DOWN
KEGG_CALCIUM_SIGNALING_PATHWAY	PLN PTGER3 AGTR1 EDNRA TRPC1 ITPR1 RYR3 ITPKB ATP2B4 TACR2 PDE1A PLCB1 P2RX5 HTR2B MYLK CACNA1H ADRB2 HTR2A PTGFR GNAL PDGFRB P2RX1 ADCY2 PRKCB CACNA1C ADCY7 PLCG2 SLC8A2 PPP3CC PTGER1 ATP2B2 ADRA1B HTR6 RYR2 PTAFR CCKAR NTSR1 ADORA2A PLCG1 PDE1B SPHK1 GNA15 PRKACG HTR5A PRKCA ITPR2 TACR1 PPP3CB PRKCG CALML5 ADCY3 PLCB2 NOS3 P2RX2 CACNA1B GNA14 P2RX6 CHRNA7 ADCY8 HTR7 PHKG1 PRKACA ADRB3 DRD1 CHRM3 GRM1 GRIN2D HRH2 CACNA1G CALML3 OXTR CYSLTR1 ADRA1D GRM5 TBXA2R P2RX3 LTB4R2 ERBB4 CAMK2B CACNA1A LHCGR CACNA1D GRIN1 SLC25A31 NOS1 GNAS GRPR PPP3R1 SLC25A4 CHRM2 GRIN2A CACNA1E RYR1 CHRM5 ATP2A1 CAMK4 ADRA1A CD38 CACNA1I CAMK2A PTK2B SLC8A1 CCKBR TNNC1 DRD5 P2RX7 PHKA1 ADCY1 CAMK2G AVPR1B HTR4 CYSLTR2 ATP2B3 CALM1 PLCB3 NOS2 AVPR1A ADRB1 HTR2C VDAC3 CACNA1S BDKRB2 CALM3 PDGFRA CALM2 PHKG2 PDE1C PPP3CA BDKRB1 ATP2A3 SLC25A6 MYLK3 CACNA1F GNAQ TACR3 TNNC2 BST1 GRIN2C F2R TRHR PLCD1 VDAC2 EDNRB SPHK2 PRKX EGFR ATP2A2 ADCY9 PRKACB ITPR3 PPID GNA11 SLC25A5 PHKA2 ERBB2 PHKB ATP2B1 VDAC1 PLCE1 HRH1 ITPKA PLCB4 P2RX4 ERBB3 CHP2 ADORA2B	0.112241	UP
HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP	BEX1 HLF TIMP3 DNAJC6 ARMCX1 MYH10 PTRF ARMCX2 CFH MPDZ SERPINI1 FAM117A PDZD2 NPR3 TRO GATA3 GRK5 HLA-DRB4 COL5A1 LRIG1 FXR1 TAL1 TPM1 HSPB1 CRHBP CACNB2 BAG3 ILF3 PRG2 KLF9 FOXO1 PBX1 SMARCA2 FAM3C ZNF148 ZNF165 HSPA13 MDK CCDC88A PPM1H DDX17 HTR1F PSEN2 KIAA1033 PTK2 FAM124B BCLAF1 HSPA5 DLK1 MSH2 RASA1 ALDH1A1 SMAD7 PHF3 ARG2 LAPTM4B ID3 PTPRD LOX RIOK3 MECOM MLLT3 CHN2 TNFSF10 HIST1H2BG PHLPP1 ASAP2 ANK3 DACH1 INPP4B PLOD2 PLCB4 TJP2 CDC14B F2RL1 HMGA2	0.112336	UP
MURAKAMI_UV_RESPONSE_24HR	EGR1 TGFB1 MAP3K14 IL6 NOTCH4 IFI6 ITGB7 IL13 RARG KRT1 SMO DVL1 VTN KRT14 TRAIP KRT10 DSG1 RFC2 EDN2 DSP	0.112536	UP
FIGUEROA_AML_METHYLATION_CLUSTER_1_UP	KIAA1462 SDPR TUBB6 TIE1 DAAM2 VPREB3 FSTL1 SCG5 EREG CLIC2 GNG11 JAKMIP2 HTR2A VWF TEK NNAT IL11RA CXCL1 DNM3 BHLHB9 ZNF667 TBC1D16 FOXJ1 CDX4 CRHBP WT1 KRT81 NEUROG1 MOS MAP7D3 SAP30BP TXNRD3 MYL4 TLR2 GTF2A1 ZNF281 PABPN1 RECQL5 VPS53 GDF3 GPR6 IPO8 PFN2 TNPO3 ZFHX2 N4BP1 PMAIP1 POU5F1 HNRNPR CISH ELAVL2 SLC38A10 CHCHD2 ZNF264 ABLIM1 FAM3A OXA1L SORL1 APIP PRRG1 GAN ENDOD1 DHRS12 CD9 ISCA1 MCTS1 PDHX PIGZ CANT1 VWA5A SLC39A14 BTBD3 PAQR5 ARHGAP44 MAP7	0.112556	UP
KYNG_DNA_DAMAGE_BY_4NQO_OR_GAMMA_RADIATION	EGR1 FGF2 SERPINE2 LIMS1 PPOX AGPAT1 GYPB UBE2N MTMR10 CYP19A1 DCTD EPHA1 EGFR LRRFIP2	0.112565	UP
CHANGOLKAR_H2AFY_TARGETS_UP	GRAMD3 CBLC AVL9 SERPINA6 CA1 SCD IVD DLG3 ILVBL APH1A WDR11 IBTK TRAF4 SMURF2 SLC44A1 TMEM176A GNAQ TMEM70 CCT8 GLO1 SLC6A8 ITPK1 SERPINA7 KRT23 CD99 MCL1 ENPP3 ATP11A SDR39U1 LPL	0.112719	DOWN
REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE	FRAT2 PPP2R1B APC FRAT1 PPP2R5A PPP2CB PPP2R5E PPP2R1A PPP2CA CSNK1A1 CTNNB1 AXIN1 PPP2R5D PPP2R5C PPP2R5B	0.113585	DOWN
KANG_CISPLATIN_RESISTANCE_UP	AHNAK2 TFPI IGFBP6 MAFF RAC2 ATP7A LZTFL1 MDK SF3B3 FAM46A METTL21B GRN FTH1 IER5 DALRD3 CDKN1A ZDHHC3 JUP	0.114078	UP
SCHMIDT_POR_TARGETS_IN_LIMB_BUD_UP	CYP51A1 ELOVL6 HMGCS1 MSMO1 IDI1 LSS FDFT1 FDPS ACAT2 NSDHL DHCR7 SREBF2 FGL1 TM7SF2 SQLE ACLY MVD MVK INSIG1 LDLR CYP26A1 ZMAT4 FOXC1	0.114363	DOWN
GERHOLD_RESPONSE_TO_TZD_DN	CRYAB CXCL12 CFD PMP22 CD81 CEBPD GHR APOE MNT MCL1 SOX4 AGT PPARG	0.11456	UP
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP	CRYAB KIAA1462 CES1 TSC22D3 EGR2 ZEB2 NID1 COL21A1 KLF2 TAGLN3 FZD7 FBLN5 CDK14 G0S2 LBH ELN TGM2 DPYSL2 KCNE4 HSPB2 ITGAM FGFR1 FYN RGS10 ADARB1 FZD4 ASAP1 PODXL ITGB2 FLI1 PTPN13 KCTD12 CD79A SIRPA ICAM2 ARHGEF6 FCHSD2 ARHGDIB FNBP1 ST3GAL5 SSPN NGFR GATA2 DAPK1 ICAM1 MAFB SIGLEC15 RAMP2 GRK5 SAP30 EPHA2 NFATC4 CDH11 DUSP6 GPR137B RARRES2 TRIB1 KMO WWC3 C1QL1 HOXD10 TNNT1 CLEC11A SEMA3F SH2B3 FGF18 KIT UBE2L6 TRIM62 SLC17A7 SH3GL3 STAR TM4SF1 TBC1D9 NPTXR SLC43A1 MDFI KSR1 FOXL2 YPEL5 DPF3 CSPG5 PGF MAP7D3 FZD8 PRND AKAP13 JAK1 PTPN22 ADRA1D MMP3 CD99 SIX1 SLC1A4 RCN3 LRCH1 FARP1 HIP1R EPOR BAHCC1 C9orf116 CHST1 USP6NL SLC7A11 IFITM1 BHLHE41 NTNG1 DNAJC12 GLG1 PHKA1 KALRN ID2 KCNN1 EFNB1 SPTBN1 EPHB3 EPB41 CUL4B RALGPS2 JAG1 KDSR IL1RAP GSTM1 HS3ST3B1 CLDN1 DGKD BCL2L1 ETV6 SSBP3 HLA-E HIPK1 TCF12 ABHD6 FKBP1A PTTG1IP DPP4 ERCC6 SLC12A6 NKX2-2 EPHB2 ROCK2 CDK1 NMI SPTLC2 DCAF7 ADCY9 RPS6KA5 CHMP1B CD58 TSPAN13 EMP2 EFHD2 SOX4 FAS RNF19B FUCA1 HAPLN1 ATP1A1 MLLT3 EZH2 PPARA LGALS8 SYNE2 AKAP7 GCH1 ANKH CPPED1 SORD SULT1A1 TMEM164 IGFBP2 KLF3 MALL APOL6 TBL1XR1 OPN3 KRT18 STEAP3 KRT19 SLC26A2 CASP3 RCOR1 HMGB3 SLC35F2 P2RX4 CEACAM1 PADI2 RAB11FIP1 MAPK13 PAQR5 IMPA2 GSTM4 SMAGP GALNT3 GLCE HSD17B2 AKR1B10 GPD2 STEAP1	0.115023	UP
REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE	EDEM3 MLEC UGGT1 EDEM2 PDIA3 GANAB MAN1B1 CANX CALR EDEM1 MOGS UGGT2 PRKCSH	0.115117	DOWN
DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN	AHNAK2 FGF13 STON1 TFPI NBEA EFEMP1 GRB14 EFHD1 CRISPLD2 NUAK1 KYNU ALCAM ARID5B TGFB3 SSBP2 DRAM1 NR3C1 ST8SIA4 CTNND2 ZNF467 MME CDK6 SGCG UTRN TGFB2 CLEC2D KLHL24 MTAP ERBB4 ATP6V0A4 ABCC5 EPB41L5 MMP16 N4BP3 IL1R1 PTGER4 KAT2B RND1 RAB27B CDKL5 SH3BP4 EPAS1 PLEKHF2 PLA2R1 TNS3 NEDD4L GALNT10 ZDHHC7 BLNK INPP5J CCNG2 RCAN1 LMO7 BAK1 KIAA0513 DNAJC15 ERBB2 LIMA1 PLIN2 AIM1 TSPAN12 HSD17B11 EFNA1 GRB7 MYO1B ACAA2 IRF6 EGLN3 ITGB6	0.11522	UP
PID_LYMPH_ANGIOGENESIS_PATHWAY	FN1 VEGFC ITGA5 ITGA1 COL1A1 COL1A2 ITGA4 FLT4 PIK3CA AKT1 PIK3R1 MAPK11 ITGB1 SHC1 GRB2 CREB1 MAPK3 MAP2K4 MAPK14 SOS1 CRK RPS6KA1 MAPK1 ITGA2	0.115368	UP
HASLINGER_B_CLL_WITH_13Q14_DELETION	TPM2 ID4 PNMA2 SSBP2 TUBB4A BCL7A TUBB LDLR ALOX5 DUSP8 EPB41L2 RNASEH2B EFNA2 TRIM16 RB1 RBMS2 ITGB5 TRIM13 ARL4A KLF4 TUBGCP4 CTSA	0.11543	UP
KEGG_COLORECTAL_CANCER	FOS TCF7L1 AKT3 TGFB1 JUN TGFB3 MAPK10 PIK3CD RAC2 TCF7 CCND1 MSH6 MYC PIK3CG TGFBR2 BCL2 LEF1 PIK3R3 APC2 PIK3CA TGFB2 RALGDS AKT2 AKT1 PIK3R1 RAC3 DCC TGFBR1 PIK3R5 TP53 MLH1 PIK3R2 MAPK8 AXIN1 CTNNB1 RAF1 MAP2K1 BRAF RHOA CASP9 SMAD3 MSH2 ARAF SMAD2 RAC1 BAD BIRC5 APPL1 MAPK9 MAPK3 TCF7L2 BAX GSK3B MSH3 KRAS APC CYCS SMAD4 PIK3CB MAPK1 CASP3	0.115437	UP
HEIDENBLAD_AMPLICON_12P11_12_UP	MGP GEM ANXA6 IL7R CBR3 EIF5A RASSF8 RASA3 RPGR ABCC8 TCP11L1 CCDC91 ARID3A METTL9 ADSL SAR1A XCL1 RPA1 KIF1C EIF2B2 PKNOX1 EFCAB1 ERGIC2 PPP1R7 CTSC NTAN1 DNMBP SPA17 KCNK5	0.115986	UP
SANCHEZ_MDM2_TARGETS	IGFBP6 CLIP3 TIMP1 INHBB CCND1 IL1RN RABAC1 HIST2H2BE RNF113A HIST2H2AA3 IL13RA2 CDKN1A FCGRT	0.116441	UP
BIOCARTA_EGF_PATHWAY	FOS JUN STAT5B SRF PRKCB PLCG1 STAT5A PRKCA PIK3CA STAT4 STAT2 JAK1 PIK3R1 MAP3K1 ELK1 STAT3 HRAS MAPK8 SHC1 STAT6 RAF1 MAP2K1 STAT1 GRB2 RASA1 MAPK3 MAP2K4 SOS1 EGF EGFR CSNK2A1	0.116495	UP
BIOCARTA_GCR_PATHWAY	ANXA1 ADRB2 NR3C1 PIK3CG PIK3CA NPPA NOS3 RELA AKT1 PIK3R1 GNAS HSP90AA1 GNB1 CALM1 CORIN CALM3 CALM2 GNGT1 NFKB1	0.116717	UP
KEGG_ABC_TRANSPORTERS	ABCG2 ABCB11 ABCC6 ABCD3 CFTR ABCB1 ABCC3 ABCG1 ABCC4 ABCA5 ABCG5 TAP2 ABCB8 ABCB7 TAP1 ABCD4 ABCC10 ABCG4 ABCA12 ABCB6 ABCA2 ABCC5 ABCA4 ABCC9 ABCC8 ABCA1 ABCA7 ABCC2 ABCD2 ABCC1 ABCB9 ABCA6 ABCD1 ABCB4 ABCA3 ABCA8	0.116964	DOWN
ZHENG_RESPONSE_TO_ARSENITE_UP	GCLM HMOX1 SLC30A1 PEX2 UAP1 MT1M TXNRD1 MT1E MT1G MT1H MT1X DNAJB1 MT2A HIST2H2BE FOSL1 BCL2 KCNK3	0.117326	DOWN
ZHANG_PROLIFERATING_VS_QUIESCENT	CTGF AXL TIE1 ITGA5 MCAM JUN CXCL2 TEK CCND1 CDH2 CCND2 HSPB1 DDIT3 RELA CASP4 PLAUR GNAS GPX1 RPL6 ITGB1 ITGB3 RPS19 HSP90AA1 MDM2 MARCKSL1 PTMA TCEB1 SKI MAP3K11 NME2 GRB2 TMSB10 GSTM1 GSTP1 RHOA ITGAV DYNLL1 GADD45A SOD1 GPI DAD1 BAX PRDX2 CCNG2 RAD23B NDUFB7 ITGA6 IGFBP2 CCNB1 CASP3	0.117417	UP
PID_INTEGRIN5_PATHWAY	CYR61 FN1 FBN1 VCAM1 ITGA4 MADCAM1 ITGB7 EDIL3 PLAU PLAUR TGFBR1 ITGB8 VTN ITGAV ITGB5 SDC1 ITGB6	0.11747	UP
REACTOME_SIGNALING_BY_BMP	CHRDL1 GREM2 FSTL1 ACVR2B BMPR1A CER1 BMPR1B SMAD6 SKI SMAD5 SMURF2 SMURF1 UBE2D3 SMAD7 UBE2D1 ZFYVE16 BMPR2 SMAD1 SMAD4 ACVR2A BMP2	0.117503	UP
NIELSEN_LEIOMYOSARCOMA_DN	SFRP1 MN1 DAAM2 LIMCH1 TBL1X PBX1 RPP30 TRAK2 ABLIM1 PMEL LRP5 ADD3 PRDX2 HR EPHX2	0.117542	UP
KANG_AR_TARGETS_DN	SPP1 TGFB1 COL1A1 COL1A2 VEGFB CTSK ANXA5 FGF1 MMP8 IBSP MEPE DMP1 ALPL ITGB1 DSPP VEGFA SMAD1 SLC20A2 SLC20A1	0.117788	UP
DARWICHE_SKIN_TUMOR_PROMOTER_UP	FABP4 ACTG2 APOD ACTA2 AXL SPP1 MCAM RHOH S100A8 PTPRCAP CX3CL1 LY6E CD248 PLEKHA4 ENAH SOD3 ENG SRM ICAM1 GNAO1 IFITM3 LTBP4 HOMER3 BATF3 C6orf48 S100A9 ACAN BAIAP2 NPTXR MAN2A2 TRMT1 FOXL2 WFDC2 LTB4R CRELD1 TP73 ARAP1 CHI3L1 PRG3 NCL C9orf16 HAMP CACNA1E RYR1 RPS6KA4 LHX3 PDCD5 ARL2 STX16 DRD5 CCT4 TRAF2 ELAVL1 RPS3A LIF H2AFZ RBM12 EEF1B2 ESD PGAM1 NHP2 ARHGAP4 HBS1L SUN1 GABARAPL2 TNP2 NCAN FTL DYNLL1 SRSF1 OR7C1 IRAK1 TCP1 CITED2 ENO1 DNAJC1 YWHAB CA3 MAP2K5 QDPR UBE2C ID1 SMU1 BZW1 C20orf24 LRIF1 LDHA PFKL EXT2 SOD1 PGK1 MRPS18A PPIC GSK3B COX5B GBA CAPN2 ATP6V0D1 IDE CHPT1 CHKA SLPI KLF13 EML4 PLAC8 OVOL2 TGFA	0.117868	UP
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK	PPARG ACOX1 PCCA TMEM33 HIBCH NCBP1 HADH SORT1 SFXN1 ACAA2 IDH1 FDX1 ACADM CPEB3 PANK3 SCARB2 BCAR3 ALDH6A1 MTCH2 HSDL2 PCYOX1 DGAT1 AGPAT2 BCL2L13 ATP5G3 CHPT1 ABCC4 GHITM FAM13A MSMO1 SLC25A46 PXMP4 PC CHCHD3 MTUS1 GCSH IMMT ESRRA ETFB G3BP2 ADIPOR2 PPM1B HSD17B12 ATP1B3 ALAD CS LRRC8D BCAT2 NDUFS6 PFKL ACSL3 TOB2 TXLNG ATP5J MLF2 EFR3A QDPR LSM12 EIF4G3 CERK PLEKHF2 ZNF219 ERP29 BFAR AFTPH SLC1A5 PEX5 MKNK2 PFKFB1 MOCS2 NFE2L1 PAM16 IFNGR1 TANK AP3S1 KAT2B PLA2G15 KLF15 PARL FAM102A LONP2 CSAD KLHL25 PQLC3 REEP5 PLA2G6 PEX3 ADAMTS12 NR1D1 ATN1 PNPLA2 BAZ2A NMT1 FAM49B CYTH1 XRCC3 RASA3 YPEL5 KSR1 PLOD1 SLC48A1 LIPE AOX1 STOM FADS2 CERS4 MAPKBP1 CD302 GPRC5B LTBP3 PLA2G16 PRNP PLCB1 LPL ADIPOQ FABP4	0.117988	DOWN
REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX	ORC2 CDC6 ORC5 ORC4 ORC1 E2F2 ORC6 E2F3 ORC3 E2F1	0.118053	DOWN
SEIDEN_ONCOGENESIS_BY_MET	ANXA3 F2RL1 UGDH PLOD2 SLC25A24 ANXA4 TSPAN8 PDE8A EPS8 HIGD1A ITGA6 SEC23A ADAM9 CD46 MSMO1 LYPLA1 SPTLC1 CERS6 RIOK3 GLS SCP2 COMMD8 TMX1 GRSF1 GBAS EIF5 ARHGEF12 CDK1 PAPOLA FAM208B GNAI3 DPM1 PPP1CB HSPA4 AASDHPPT PTEN MMADHC NCKAP1 PNRC2 C6orf62 RRM1 YME1L1 SERBP1 PCMT1 CAPZA1 HNRNPH2 P4HA1 SERP1 ACTR3 HAT1 CXCL5 CCT6A STAT1 TRAM1 SRP72 IFNGR1 SUB1 TCERG1 COMMD3 TMEM123 IPO7 HNRNPA3 HSP90AA1 LAMB1 SERINC1 IFITM1 MBIP ATP2A1 CSDE1 TAF1D NSA2 ZBED5 MBNL1 NPM1 TCEA1 AIDA UBA2 RSL24D1 SLC38A2 SH3BGRL SLC39A6 EEF1A2 CLIC4 PLS3 EREG	0.118433	DOWN
REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN	MPI PMM1 ALG6 ALG13 GMPPA DOLPP1 DPAGT1 PGM3 DPM3 ALG5 ALG8 ALG3 PMM2 ALG9 DPM1 GMPPB DPM2 DOLK ALG12 GFPT2	0.118638	DOWN
ZHAN_MULTIPLE_MYELOMA_CD1_UP	MFAP4 G0S2 RAB31 CSTA PHGDH FYN RAB33A BGLAP ITGAL TM6SF1 CEBPB RBP1 BATF3 TBC1D16 STC2 TMC6 INHBE TRIB3 CLEC2D EIF4EBP1 ATF5 KLHL4 GPR63 SLC7A11 NID2 ADRB1 PTGER2 PPP2R5E MTG1 PCK2 HADH CTH	0.118832	UP
REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS	ETNK1 SLC44A4 PLD1 PLA2G10 CDS1 AGPAT5 LPCAT3 LPCAT4 DGAT1 HADHA AGPAT2 GPD1L CHKA PLA2G12A CHPT1 PLBD1 HADHB MGLL LPIN2 MBOAT7 AGPAT3 PCYT2 CEPT1 MBOAT2 SLC44A1 LPGAT1 PCYT1A GNPAT PLA2G2A PGS1 PLA2G2F CDIPT PLA2G1B PTDSS1 PTDSS2 CDS2 CHKB PLA2G3 PLA2G6 AGPAT1 CHAT PNPLA2 PEMT PLA2G2E TAZ PLD2 PLA2G4A ETNK2 PITPNB GPD1 PCYT1B PLD3 ACHE LPIN1 PNPLA3 AGPAT4 PLA2G2D PLA2G4C PLA2G16 PLA2G5 LPCAT1	0.119018	DOWN
REACTOME_KERATAN_SULFATE_BIOSYNTHESIS	OGN PRELP OMD LUM ST3GAL6 CHST2 ST3GAL1 FMOD ST3GAL2 ACAN CHST6 B4GALT6 B4GALT2 CHST1 B3GNT4 KERA B4GALT1 B4GALT3 B4GALT4 CHST5 B3GNT2 B3GNT3 B4GALT5	0.120126	UP
ROLEF_GLIS3_TARGETS	SCGN PPP1R1A PCSK2 SCG5 ISL1 SLIT3 RBP4 MAFB SST INS PAX4 LDLR FOXJ1 SLC2A2 IAPP CTRL GJD2 G6PC2 PPY PAX6 NEUROG3 RIMS3 CHGA ABCC8 NKX6-1 NEUROD1 FRZB PYY SYT13 SRP9 SLC2A5 PSMB10 VDR GCG	0.120329	UP
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1	PEG3 NR4A1 LEPR DUSP1 TNXB MITF BHLHE40 BCL6 CFHR1 HSPA2 CEBPB MSC NOV WNK1 TGFBI IGFBP3 TROVE2 LTBP1 MAP3K8 ITPR2 CHD8 DDX6 KLF9 DDIT3 MYCN KCNK2 TXNIP HP MYH7 DDX17 MCM5 PER2 AMPD3 GADD45B PDK4 AKAP8L TCF25 LRP6 FOXO3 IRS2 BMP4 KRT7 NBL1 IGF1R CXCL14 GADD45G CITED2 ALDH1A1 BCL2L11 SPSB1 NET1 SAT1 ID3 MTCP1 ADAMDEC1 PARM1 NDRG1 ENTPD5 TFCP2L1 GDPD3	0.120672	UP
MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED	SCGN KCND3 RASGRP3 NT5DC2 SST DPEP3 JPH2 SPAG8 PIWIL1 TAL1 POMC XYLT2 PCDHB11 FGF6 MFAP2 PCDHB12 KCNH6 TNNI3 LRRC8E TSSK2 RCVRN IL12A DCC ABCC9 NOS1 SPO11 ADCYAP1 TEX13B BAHCC1 FSCN2 GLRA1 PRM1 CRYGA BRDT COL8A1 EDAR FTL SSTR2 PCDHA9 PCDHA6 PDHA2 CLIC5	0.121067	UP
TAVOR_CEBPA_TARGETS_UP	KCNMB1 AKAP12 BCL2A1 RGS2 ANXA1 CXCR4 SERPINI1 RAB31 SERPINF1 PTPRC BTG2 EXTL2 GLIPR1 LST1 TRIB1 EEF1A2 HCAR3 C3AR1 ARC S100A9 CCND2 VCL ARG1 MLC1 CD7 BTG1 GBP1 IL1RN SERTAD2 TANK DYNLT3 FIG4 ACSL1 PTX3 BIK SOD2 SECTM1 LITAF KIAA0513 GCH1 ARHGEF5 SPINT2 NFIL3 HMOX1 KLF5 CA2 PTPN3 GGH	0.121106	UP
TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_UP	FOSB NR4A2 ATF3 PNMAL1 KLF11 MAFF FAM49A CX3CL1 GATM MR1 CELF2 ST3GAL6 PMEPA1 ACACB RFXAP MTAP KRT23 LRCH3 PHF20L1 GABRP DCAF8 TMPRSS3 EXOSC8 CHML SMG8 MAK16 RBBP4 ZNF250 DBR1 VPS13B KRT6B ADNP SMAD5 FRMD4B MTMR4 PTX3 USP25 COQ10B PDE4DIP SMUG1 RPE SKP2 MAP4K5 GLUD2 EPPK1 SPATA5L1 CLCN3 PBLD MYO1D GALNT3	0.121123	UP
JAEGER_METASTASIS_UP	UCHL1 TUBB2B SULF1 SCHIP1 NCAM1 THBS4 FN1 SPP1 SNAP25 BGN STC1 MME TACC3 MERTK TBC1D1 MAGEA12 HLTF MAGEA3 ADAM12 FCGR1B GINS4 MAGEA6 H2AFV RRM2 NCBP2 NCAPG SMC4 SLC16A3 GPI KIF2C NUDT9 NNT CENPF CDC6 CKS2 MET EPS8 DDAH1 DTL PAPSS2 PLOD2 AURKA ENPP1	0.121462	UP
GRANDVAUX_IRF3_TARGETS_DN	GEM MFAP5 TIMP3 TYRP1 PLAG1 CDH11 FGF1 CD1B RPS7 PAH RASA1 STK17B SORL1 PIK3C3 PPP2R3A CD58 TMPO ADAM9 ANXA4	0.121532	UP
DAZARD_UV_RESPONSE_CLUSTER_G4	CDKN1C DUSP1 ZFP36 H1FX TUBB4A SOX15 TUBB3 SULT2B1 GADD45B PFN1 ARHGDIA TUBB4B MMP10 TUBA4A PPP2R1A APRT KRT34 XBP1 HIST2H2AA3 CAPNS1 PRSS3	0.122004	UP
HAHTOLA_CTCL_CUTANEOUS	ZBTB16 G0S2 MMP9 MS4A4A ITM2A GLIPR1 TRIB1 BARD1 HBD RECQL SNCA GLUL RPL31 LILRA5 STAT1 HIST2H2BE S100P TOP1 PSMB3 CDC42 CD160 C1QBP YWHAE ARPC1A ETHE1	0.123233	UP
ZHAN_MULTIPLE_MYELOMA_PR_DN	FGF2 RASGRP3 ALCAM PLCL1 ARID5B CBX7 ZBTB20 ZHX2 DPYD MAP2 PHF1 CNTN1 TFEB DUSP26 SATB1 SOCS1 TK2 DDHD2 SLC7A7 EPS15 CYLD JMJD1C KAT2B PRDM2 RSBN1 BAZ2B GAB1 BCL10 BLNK SH3GLB1 SYNE2 NR3C2	0.123256	UP
MCGOWAN_RSP6_TARGETS_UP	PCOLCE2 GPNMB PTGDS PTP4A3 SOX10 AAAS TRPM1 MGMT SLC45A2 MDM2 GLRX3 EPHX1 EDNRB NNT ZDHHC3	0.123353	UP
BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE	TSC22D3 CD69 CXCL13 NR4A3 MAL STAP1 BHLHE40 MEOX1 BCL6 AKAP2 TIAM1 PLLP ASAP1 PECAM1 TNFRSF9 RASGRP3 PLXDC1 PLCL1 ITK CCL22 CYTIP LRRC32 CD83 LCP2 IL36A DUSP4 DUSP5 IKZF1 BCL2 CD84 IL2RA DACT1 IKZF4 MEF2C BATF SLCO3A1 FCER2 IRF4 FLT3LG ALOX5 APBB1IP TAF4B TBC1D1 IL1B FOXP3 CSF1 IL13 SOCS1 ELL2 STAT4 SNTB1 BTG1 CYSLTR1 CNKSR2 RRAGD DARS SEMA7A FURIN SGSH RRS1 RPL5 KRT1 GNPDA1 PHF20L1 GFI1 CYLD RAB30 HIPK2 TRAFD1 NAT9 IL5 RAP1A NCOA3 CCL1 IL4R LIF RAP2B CYSLTR2 NRCAM KPNA6 RAB27B ID2 TNFRSF14 CISH HIST2H4A PTGER2 POLR2M BCL2L1 TPP2 HIPK1 PITRM1 ENO1 TAB2 DHRS3 XBP1 DPP4 STK17B SERPINB6 SOCS2 YEATS4 IMMT MKRN1 ISCA1 CERS6 MRPL35 KLF3 SLC12A2 SEMA5A SPINT2 PGM1 HPGD CASP3 CDH1 IL17RB CEACAM1 SLC39A8 ETNK1	0.123771	UP
AIYAR_COBRA1_TARGETS_UP	MGP APOD SERPINA3 S100A8 DEGS1 TIMP1 ENAH MAPK8IP2 AREG SATB1 NENF TRIB3 PBRM1 C1orf159 PIP FRS2 ASNS IFITM1 PRCP CTSB MBTPS1 PRLR TOMM20 EPRS CLDN1 ACOX2 DNAL4 GADD45A TMEM50A TPBG RRNAD1 ASS1 FBXL6 FHL2 UBL3 PARP4 NEK2 TFF3	0.124117	UP
REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING	NOTCH3 JUN MFNG MAMLD1 NOTCH4 ST3GAL6 CCND1 RFNG RBPJ NOTCH2 KAT2A LFNG E2F1 FURIN MAML3 TNRC6B CREBBP ATP2A1 TP53 POGLUT1 KAT2B SNW1 POFUT1 E2F3 MAML1 ATP2A3 SEL1L RAB6A TMED2 B4GALT1 EP300 TFDP1 ATP2A2	0.124133	UP
REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING	PCSK2 CPE MYO5A SNAP25 INS VAMP2 PCSK1 STX1A KIF5B EXOC3 EXOC2 RAB27A EXOC5 EXOC1 SLC30A5	0.124543	UP
REACTOME_POTASSIUM_CHANNELS	KCNMB1 KCNN3 KCNH2 GABBR1 KCND3 KCNJ8 GNG3 KCNAB1 KCNK3 KCNA5 KCNMB4 KCNQ4 KCNAB2 KCNA1 KCNJ12 KCNA10 KCND2 KCNN2 GNG7 KCNC2 KCNMB3 KCNB1 KCNJ14 KCNAB3 KCNA6 KCNK7 KCNA2 KCNH6 KCNH4 KCNK2 GNB3 KCNG1 KCNJ5 KCNF1 KCNC1 KCNH1 ABCC8 KCNJ10 ABCC9 KCNJ3 GABBR2 KCNK4 KCNJ4 KCNQ2 KCNC4 KCNQ3 KCNJ9 KCNMB2 GNG4 KCNA3 KCNV1 KCNV2 GNB1 KCNJ1 KCND1 KCNN4 KCNA4 KCNJ15 KCNN1 KCNJ16 KCNS1 GNB2 KCNB2 HCN2 KCNK13 GNGT1 HCN4 KCNJ6 KCNC3 GNG5 KCNQ1 KCNK10 KCNS3 KCNG2 GNG12 KCNK1 KCNJ2	0.124574	UP
REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	NOTCH3 MAMLD1 NOTCH4 RBPJ NOTCH2 KAT2A MAML3 CREBBP KAT2B SNW1 MAML1	0.124694	UP
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_DN	TGM2 ARHGAP15 LGALS1 CD81 DOCK10 GRB10 PPBP CDC42EP3 PRKD3 SLC6A13 GSTA4 SMO CNN3 TMSB10 SOX4 GALNT7 HOXA9	0.124793	UP
PID_IL5_PATHWAY	CSF2RB STAT5B STAT5A PIM1 LYN PIK3CA PTPN11 PIK3R1 IL5 IL5RA SDCBP JAK2 GRB2 CISH	0.124859	UP
GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN	UCHL1 GREM2 PLCL1 ARHGAP22 AHI1 MLF1 IAPP TLE4 CHAC1 KLHL4 ASNS SLC7A11 RNF187 BCS1L NPY1R ERMP1	0.124905	UP
REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	AKT3 PLCB1 GNG11 GNB5 GNG3 PIK3CG GNG7 PLCB2 AKT2 GNB3 AKT1 PIK3R5 GNG4 GNB1 GNG13 PDPK1 PLCB3 GNB2 RHOA GNGT1 GNG5 GNG12	0.124983	UP
SA_CASPASE_CASCADE	CASP7 CASP3 APAF1 XIAP FAS SREBF2 BIRC2 CASP8 SCAP CASP10 DFFB CASP9 GZMB SREBF1 PRF1 FASLG DFFA BIRC3 PARP1	0.125261	DOWN
LEE_TARGETS_OF_PTCH1_AND_SUFU_UP	SDPR SFRP1 DDR2 GPNMB IRS1 FZD2 C1QA HLA-DQA1 PLEKHO2 C1QB CCND1 SOX18 MTHFD2 CDK6 GLI2 GLI1 PPAN CCND2 TSHZ2 MICAL1 MYCN MAGOHB RPL23 EIF4EBP1 CDH20 POLE MCM6 PTCH2 CKLF KIAA0556 B2M RND3 LAP3 SSTR2 FRMD4B SOCS2 MCM2 IER5 ATOH1 CTSS RAD51AP1 HK2 MAP2K6 HSD11B2	0.125653	UP
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_24	MLLT11 PRRX1 FCGR2B NTRK1 PBX1 BCL9 TPM3 PRCC ARNT MUC1 CDC73 SDHC	0.125947	UP
HUANG_GATA2_TARGETS_DN	EGR1 GUCY1A3 CLU ARHGAP29 FHL1 LMO2 PODXL TMEM109 GATA2 PDGFB SLC2A3 ST3GAL6 TACC1 GP1BB MTHFD2 SSSCA1 LAT KLF1 PHLDA1 DAAM1 TRMT61A RRP1B TCOF1 SLAMF1 PBX1 FAM3C TMEM132A SLC1A4 CHAC1 EIF3D JMJD6 ASNS SHMT2 PFAS IPPK ACTB ETF1 DIAPH3 DCTD TXNDC5 GBX2 E2F2 RABGEF1 NUP107 PF4 GOLT1B SLC2A1 PIGT PDCD4 FDPS SKP2 TFRC PARM1 PLAGL2 NSF SLC6A9 RCOR1 HK2 AURKA	0.12596	UP
DELASERNA_MYOD_TARGETS_UP	IGFBP5 HSPB8 PDLIM3 IGF2 RHOB PLEKHO1 SCHIP1 KIF5C BCL6 DBN1 PRKAR2B DMPK DYSF VASH2 FZD3 MYOG CACNA2D1 BIN1 FCER1G ENO3 TNNT2 KIFC3 ACTA1 VKORC1 PBXIP1 HIP1 NAV2 CKM MYOD1 CCND3 MYH3 CD82 TNNT3 PRND AKT2 TNNI2 MYBPH SH2B1 MYL4 PACS2 MYLPF MYL1 ANKS1B MEF2A DCAKD CHRNG RBM25 PPFIA4 ATP2A1 CHRNB1 HRC GYS1 PVR HS2ST1 CELF1 RB1 HDAC11 KLHL5 LMNB2 PRSS23 PSMC3 GADD45G RUNX1 TNNC2 STK17B SCRIB KLHDC10 STAM ANXA11 CPSF6 CDKN1A ATP1A1 TFRC CHRNA1 CPEB3 LGALS4 AGPAT5 KLF5 LRP4 HMGCS2	0.126001	UP
RASHI_RESPONSE_TO_IONIZING_RADIATION_6	PLEKHO1 CXCR4 CXCL13 EMP3 MS4A1 CD79B SORBS1 RHOH FCGR2B PIP4K2A S100A8 CD48 EVI2A PTPRC LAPTM5 CSF1R HHEX TYROBP FMNL1 CFP CCR2 MSC MRPL41 IKZF1 PTP4A3 UBD S100A9 ALDOC NPY2R IFIT1 SELPLG IL18R1 CSF2RA RNASE1 SEC61A2 MBTD1 DDX18 ACIN1 GBP2 HTR1D UNC93B1 CXCL9 BRIX1 NONO RNF38 PQLC3 SNRPB2 CCL5 INCENP ZNF688 MAZ TCF25 ASH1L PSMB9 BAG6 CUL2 CCNJ TMEM70 KNG1 DDX52 ALDOA FAS EIF4EBP2 SLPI RAD51AP1 C9orf40 ARNTL IL1R2 ADH1C SLC38A4	0.12604	UP
GHANDHI_DIRECT_IRRADIATION_UP	PTGS2 IL33 C8orf4 BCL2A1 NEFM MYBL1 G0S2 PLK3 CXCL2 FGF2 KYNU PTGFR DUSP2 GDF15 TESC RGS9 ICAM1 IL6 HSD11B1 CXCL1 AEN THSD1 TNFAIP3 SLC16A6 INHBA BBC3 LRP8 BTG3 PRDM1 ZMAT3 CYP26B1 GPR68 FRMD4A IL1B BIRC3 POLH TNFRSF10C IL11 OR11A1 MMP3 IL12A HSPA4L PPP6R1 EYA3 GDNF CCK CXCL3 SLC7A11 ANXA10 SERPINB2 MDM2 LIF DKK1 POU5F1 MMP10 OSBPL3 CXCL5 RELB SESN1 CLDN1 IL1A GADD45A MT2A TRIAP1 TNFRSF10B PTPRE SLC16A3 MT1X MT1H MT1G ASCC3 MT1E SOD2 SMC5 CDKN1A FAS PLCL2 GCH1 BMP2 SLC30A1 LAMC2 NAMPT C3orf52 MMP1 LAMB3 PLEK2	0.126887	UP
BIOCARTA_CERAMIDE_PATHWAY	AIFM1 MAPK1 FADD SMPD1 CYCS RIPK1 BAX MAP2K4 MAPK3 CASP8 BAD NFKB1 NSMAF MAP2K1 RAF1 TNFRSF1A MAPK8 TRAF2 MAP3K1 TRADD RELA BCL2	0.127022	DOWN
ZIRN_TRETINOIN_RESPONSE_WT1_UP	AKAP12 DLC1 IGFBP6 ITGA1 ETV1 ZNF133 IGFBP3 TAL1 KIT NAV2 RARB CLDN11 PLAUR PDGFRA SMAD3 DHRS3 CAPN7 GDE1 RARRES1	0.127411	UP
WANG_METHYLATED_IN_BREAST_CANCER	PTRF CAV1 HBEGF DUSP1 MAFF FYN GDF15 SLC7A5 ZYX EPHA2 INHBA TUBB ETV5 SPHK1 FOSL1 CDC25A SLC3A2 KRT17 KLF6 GJB3 STK17A DKK1 IRS2 GADD45A TNFRSF10B SMURF2 SERPINB8 THBS1 PTPRG SLC9A1 CTNNA1 CLC F3 MYO1B UPP1	0.127579	UP
PID_RHOA_PATHWAY	CYR61 FOS RDX JUN MSN PKN1 TLN1 SRF MAPK12 MKL1 PIP5K1C PPP1R12A ACTA1 VCL LIMK1 PLD2 MYL2 ROCK1 PARD6A ITGB1 F2RL2 MAP2K3 MAPK8 DIAPH1 ATF2 CDKN1B PIP5K1A SCAI RHOA SH3GL2 CFL1 PTEN EZR CDC42 MAP2K4 ROCK2 SLC9A1 PRKCZ CIT PKN2 LIMK2 PIP5K1B MAP2K6 PLD1 SLC9A3	0.128113	UP
VERHAAK_AML_WITH_NPM1_MUTATED_UP	VNN1 CLU BCL2A1 MEIS1 SCHIP1 CYP1B1 PBX3 G0S2 BCL6 EREG DPEP2 CHST15 CAMK1 SLC15A3 BASP1 HOXB2 C1QA CXCL2 CTSG VNN2 TNFAIP2 MCTP1 RASGRP3 SNX10 PRKAR2B AIM2 C5AR1 GDF15 ARHGAP22 ADCY2 FOXC1 MAFB CD86 SNCAIP IER3 IL6 CPVL CCL4 CX3CR1 FCN1 C1QB FCGR3B PPBP CCR1 FGR CD163 TRIB1 SLC2A6 PLEK FGL2 MMP2 PIEZO2 HCAR3 TNFAIP3 CCL20 HOMER3 PTAFR FPR1 HOXA4 C3AR1 TBXAS1 LILRB2 CARD9 NINJ1 LILRA3 PILRA SCPEP1 HIP1 LTBP1 NFKBIA PHLDA1 FTO TCIRG1 C2 WARS LILRA1 LILRB1 IL1B CD14 PLA2G4A IRX5 TYMP NFKB2 IFI30 TTC27 PLAUR HCK TLR4 CD36 FCGR2C HOXB3 STS RHAG VCAN CCL23 CXCL3 HK3 TRIM16 LMNA ITGB3 SERPINB2 TREM1 CCL1 CXCL10 COL4A5 LILRA5 CD300C HIST2H2BE JAG1 SPINK2 PRDM2 ACSL1 ETS2 AQP9 GNS LGALS2 TMEM176A TARP RUNX1 LILRA6 PF4 THBS1 PELI1 HOXB5 PTX3 GGT1 S100A6 TNF SMC4 SLC16A3 LAPTM4B TMEM176B SAT1 IGF2R SOD2 CAST DMXL2 MARCKS PRKCD LGALS3BP SECTM1 CTSD HOXA6 HOXA7 CAT HOXA10 PDGFD PHKA2 ABCC4 GCH1 CASP1 EPB41L3 HOXA5 SCO2 TNFSF10 AKR1C2 ABHD2 NAMPT SERPINA1 MVP QPRT FBP1 HMOX1 KCNK5 SMPDL3A HNMT SORT1 APOBEC3A PLS1 HIST1H1C KCNJ2 HOXB6 HIST1H3H HOXA9 HIST1H2BC DEFB1	0.129114	UP
ABBUD_LIF_SIGNALING_1_DN	DDC BCKDHB CAPN9 SUCLA2 HK2 TSPAN7 ITGA6 CD24 CYFIP1 OSTF1 DCAF11 ANKRD40 PELI1 EFNA2 REXO2 GRIA2 MTSS1L AHNAK ENPP2 LIMS1 FOXA2 ALCAM S100A4	0.129689	DOWN
ZHAN_MULTIPLE_MYELOMA_LB_DN	WIPF1 BASP1 MAN1C1 PTPRCAP PARP8 LY6E TRAF5 DUSP6 TACC1 CCR2 IFI6 MX2 DIRAS2 CASP4 STAT2 XAF1 HIF1A IFIT5 CKLF USP18 GTPBP1 STAT1 SEPHS1 ZMIZ1 CAP1 IRF1 IFI35 RTP4 PSMB10 SMAD1 IFI27 DDX60 RSAD2	0.130184	UP
LUI_THYROID_CANCER_CLUSTER_2	TPM2 ZCCHC24 ITPR1 SYNE1 KIF5C ELMO1 WFS1 BASP1 CNR1 RAPGEF3 IPCEF1 TULP3 MFAP3L PATZ1 CRELD1 GABBR2 HIC2 SECISBP2L NID2 PPIL2 TP53I11 PPP1R13B BNIP3L SLC7A8 RDH11 PAN2 ACADVL ID1 TOB2 SLC16A3 VAPB SCNN1A EPB41L3 SORD ACAA1 ABCC3 WWC1 FBP1 ATP10B PPARG	0.130479	UP
REACTOME_DIABETES_PATHWAYS	BCHE ATF3 IGFBP5 CCL2 IGF2 PCSK2 IGFBP6 WFS1 CPE MYO5A SNAP25 CTSG TLN1 TSPYL2 INS MMP2 VAMP2 EXTL3 IGFBP4 PLA2G7 LEP IGFBP3 PAPPA NFYB PPP2R5B ARFGAP1 DDIT3 IGF2BP3 ADD1 IGFALS PAPPA2 PCSK1 EXOSC9 EXOSC7 EXOSC1 SPCS3 ATF4 STX1A FKBP14 CUL7 KLK3 GH1 ZBTB17 GSK3A DCTN1 ERN1 CXXC1 EXOSC2 ASNS SRPRB KIF5B F2 LMNA SEC31A DDX11 EXOSC8 MBTPS1 SSR1 SHC1 TPP1 EDEM1 DCP2 EXOC3 TATDN2 ATF6 EXOC2 NFYA EIF2S1 HSP90B1 HSPA5 SPCS2 KHSRP EXOSC4 EXOSC5 HYOU1 SERP1 KLHDC3 SEC11A DNAJB9 PARN GOSR2 CALR PREB ACADVL HERPUD1 HDGF IGFBP1 PDIA5 PLG XBP1 DIS3 PDIA6 RAB27A CTDSP2 KDELR3 SPCS1 IGF2BP2 MBTPS2 EXOC5 DNAJC3 KLF4 EXOC1 EIF2AK3 SULT1A3 SLC30A5 ATP6V0D1 YIF1A IGFBP2 MMP1 WIPI1 GCG	0.130543	UP
KENNY_CTNNB1_TARGETS_UP	CYR61 IGFBP5 SYNE1 SPP1 SORBS1 S100A8 PKN1 TNFAIP2 RAMP3 CELF2 MMP2 TACC3 TM4SF1 LOXL2 CASKIN2 CCR5 CAPN3 CD14 PTPN22 BTRC CSE1L EXOSC2 RPA2 SRSF7 HMGB2 RBM26 KRT7 HAT1 SERPIND1 ETAA1 ARCN1 BAD CTSC TK1 NCOR1 TFDP1 EBNA1BP2 PLK4 ABI1 GAN GNA11 ARFGEF2 SEPHS2 SQRDL CCNB1 UPP1 ECT2	0.131515	UP
BAKKER_FOXO3_TARGETS_UP	P2RY14 CR2 RGS2 DCN NQO2 SIRPA CSF2RB GNAI2 DUSP4 ATP7A PIK3IP1 KIT ULK1 VCL AMPD2 ARG1 BTG1 KLF6 VOPP1 NKIRAS2 DSTN XPO7 DCP1A NF2 RBL2 DNAJC12 GRIA3 PNPLA6 CTSE CDKN1B SESN1 ASAH1 CCPG1 PINK1 IGF1R HIPK1 DENND5B CITED2 SFT2D2 OSBPL9 SLC12A6 BZW1 ATP1B3 CCNG2 TMX1 CPT1A PGGT1B	0.131527	UP
AMUNDSON_GENOTOXIC_SIGNATURE	FOS EGR1 MGP GEM AXL NR4A3 PDLIM7 ACSL4 CD48 ITGA4 FSTL3 PHLDA3 IER2 LCP2 TOR1AIP1 MFGE8 ST8SIA4 SEMA4D PPP3CC MYC CDKN2C DUSP5 NR2F1 MEF2C PRR3 FGF18 DISC1 PHLDA1 TFPI2 PAQR4 BRF1 DDB2 ARHGEF2 DCT RHBDD3 AKAP13 KISS1 GLS2 RARG SIVA1 GABRA6 TKTL1 E2F5 SPRY2 SP100 DDX3Y GFI1 GRIN2A CHST1 RPA2 PKMYT1 ARPC4 CDC45 ABCF3 ZNF211 CDR2 TNFRSF17 GTPBP1 KDM3B BMP1 PPP1R8 TOR1A BUB1 IRF2 PCNA KPNA2 SCAMP2 CCNH TARDBP BAZ1A PPP4R2 TK1 GAB1 TNF MT1X AMD1 SAC3D1 COX7B SLC9A1 SEC24B NFE2L3 BUB1B ELF3 TAF5 CHUK ZNF217 CLN5 ZWINT HK2 AURKA CENPA GFPT1 HMGCR AMACR	0.132092	UP
KIM_GERMINAL_CENTER_T_HELPER_DN	CDK14 S1PR1 ZNF331 PER1 DOCK4 SVIL CLASP2 RORA ELL2 DUSP8 IRS2 SPTBN1 RYBP MEMO1 DHRS3 USP12 OSBP RAP1GAP2	0.132148	UP
HOEBEKE_LYMPHOID_STEM_CELL_DN	BEX1 TNS1 RGS2 CFH CXCR4 KLF2 MAL LIMCH1 MAFF PLS3 NPR3 TMEM45A ACTN1 IFI16 ICAM2 BST2 SRGN SERPINE2 GRK5 CEBPB NDN ICAM4 KHDRBS3 TFR2 ETV5 TAL1 HSPB1 IL1B CRYGD OXT PCIF1 PTPN11 TXNIP RPL35 NFIB SHMT2 METTL9 PSEN2 RPS27 RPS6 TCF25 RPL36A PMAIP1 FAM124B UROD HSP90B1 RAB38 COX7A2L LEPROT RPS27L DLK1 HSPA1A ACTR2 GADD45A RALBP1 BZW2 LSM5 S100A6 TMEM14A CTDSPL LAPTM4B ARHGEF12 FHL2 ELF1 C1QBP PRDX2 MARCKS KLHL7 ATP1B1 TAX1BP3 TIMM13 MECOM MLLT3 CAT AKR7A2 CKS2 TNFSF10 ALDH6A1 SUCLG2 HMGB3 PIP5K1B TJP2 SLC39A8 PHYH	0.132175	UP
DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS	PTGS2 CCL11 VCAM1 CCL3 ICAM1 IL6 SELE IL3 IL1B IL13 IL11 IL12A IL9 IL5 CCL5 NOS2 KITLG IL2 IL4 TNF EDN1 CCL13 IL18	0.132276	UP
REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN	COL1A1 FYN COL1A2 VWF GP1BB FCER1G GP1BA LYN GP9 ITGB1 GP5 ITGA2	0.132333	UP
REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS	SIRPA SIRPG TYROBP SIRPB1 PTPN6 FYB PTK2B PTK2 CD47 GRB2 SRC SKAP2	0.132609	UP
YE_METASTATIC_LIVER_CANCER	CES1 CD37 IGFBP6 SPP1 MMP9 FZD2 GRK5 ITGA9 ENO3 INPP5B PRR3 MDFI IL2RB CXCR6 KHK LILRA2 LRP6 RAB28 IRF2 AKR1C4 CYP4F12 CENPE YES1 ASPH SERPINB5	0.13269	UP
PID_FGF_PATHWAY	FOS NCAM1 SDC2 SPP1 MMP9 JUN FGFR1 FGF2 STAT5B BGLAP CDH2 FGF1 RUNX2 PLCG1 FGF18 HGF FGF8 PIK3CA FGF6 FGF4 PLAU FGF17 PTPN11 AKT1 FGF23 PIK3R1 PLAUR SPRY2 SSH1 FRS2 CAMK2A PTK2B CBL SHC1 PDPK1 STAT1 GRB2 PAK4 SRC GAB1 MAPK3 SOS1 CTTN FGFR3 RPS6KA1 FGF9 FGFR4 FGFR2 MET CTNND1 MAPK1 CDH1	0.133231	UP
SPIRA_SMOKERS_LUNG_CANCER_DN	LMO4 ALMS1 FBXW12 SPN TSR1 ZNF721 ZNF611 ZNF160 PRR11 DCLRE1C ZC3H7B NUCKS1 DUOX1 GTF2H3 RPL35A CCDC81 MZT2B ATP8B1 COX5B	0.134043	UP
WAGNER_APO2_SENSITIVITY	GALNT3 GALNT12 FUT2 FUT4 FUT3 FUT6 GALNT1 GALNT10 GALNT2 FUT5 POFUT1 GALNT8 GALNT6 FUT8 GALNT11 FUT7 GALNT14 FUT9	0.134765	DOWN
CLAUS_PGR_POSITIVE_MENINGIOMA_DN	EDNRA FSTL1 HEG1 MAP4K4 PDGFRB BCL2 TM4SF1 MEGF9 SOX4 BACE2	0.134935	UP
GOZGIT_ESR1_TARGETS_UP	FOS GAS1 FERMT2 PEG10 SGCE FRY COL21A1 FHL1 THSD7A OBSL1 SEPT6 CEP170 LIMCH1 LAMC1 CRISPLD2 DPEP2 FYN MMRN2 PECAM1 DEGS1 NPTX1 KCTD12 FAM49A DOCK10 PRKAR2B TNFAIP8 GATA2 PARVA CDC42EP3 PALM MEGF6 SERPINE1 CLSTN3 DUSP9 GDPD5 CYP26A1 IGFBP3 PIM1 CSF3R ALOX5 ACACB FSD1 AGXT TCIRG1 DHRS2 GLDC IGF2BP3 ECM1 WNT4 SPRR3 S100A12 SLC25A37 NASP CACNA1D DST TFAP2A STS KRT5 ALDH3B1 CYP11A1 SRSF11 ADAMTSL4 ALPP PTGER4 LAMB1 HSD17B1 ITSN1 SUB1 VTN HTR2C KRT14 VGLL1 CYP4F8 PTPN2 CRAT PTPN21 PMEL TH PRKAG2 ORC1 OSBPL1A TCF7L2 NAGA NT5E FHL2 COX7B BLNK B4GALT4 RNF144A PC DEPDC1 BMP2K SKP2 NR1H3 PLCL2 ME2 HERC4 FAM13A ABCG1 ACSL5 SEMA5A WWC1 ASPH ACSF2 SRI ACAA2 SMPDL3A CEBPA XDH PLD1 GNAI1 SLC16A5 IL18 ANPEP UGT8 PPARG GRAMD1C DSC2	0.135	UP
HUMMERICH_BENIGN_SKIN_TUMOR_DN	IGFBP5 CFD S100A3 CKM ACTN3 TNNT3 COX6A2 TNNI2 ATP2A1 MYH8 MYH4 ALB PCDH12 MYH2 MYH1 AFF1 PLXNB2 TNNC2	0.135008	UP
RAO_BOUND_BY_SALL4	CTGF GPM6A NEFL AKAP12 CASQ2 RHOB CFH MAP1B FN1 VEGFC KLF2 MYOT PDE1A ITGA1 TCL1A JAM2 TMEFF1 FGFR1 PHC1 ZNF532 COL4A2 MAP4K4 TFAP2C ETV1 CEP112 DUSP6 ZFP36L1 FLRT3 NPTX2 MGAT4C PDGFC MTMR12 GJA1 CHD2 KIFC3 IL6ST SLC38A2 DYRK3 DNMT3A CYB5R1 FGF4 PRDM14 B4GALT6 USP48 SOX2 GPR1 SLCO5A1 EXOSC7 MYCN ZDHHC14 REST GCM1 JARID2 ZNF148 RAX GJB3 PARP6 STMN1 SPRY2 BCAT1 RGS20 MZF1 OGT MATR3 LYRM1 EYA1 HIST1H3C LPAR6 NOLC1 ASNS MAX TP53BP1 WEE1 TP53 SRSF11 CACYBP IFITM1 TMPRSS11D SNTB2 TMEM57 UBR5 LDB1 SFTPD CST3 HNRNPA2B1 SF3B4 ARNT DKK1 STAMBPL1 CIDEA HIST1H2BJ PDPK1 SYNCRIP HIST1H2BB NR0B1 ABT1 RYBP LRPAP1 NANOG KLHL5 TLK1 RAB38 RNF13 PDHB ZC3HAV1 CHD7 MOB4 SSBP3 SERBP1 SEC16A ANP32A ATG14 WTAP SLC44A1 INSIG2 SMG7 HEXIM1 UBB AURKB DGKH KCMF1 HIST1H2AD GTF3C3 TXLNG SLC25A40 NKX2-2 MBTPS2 ARHGEF18 SLCO4C1 UBL3 NPEPPS GRSF1 ADIPOR2 TSPAN15 FRYL HEXB PRDX6 NBR1 STK38 TRIM34 TMEM8A PYROXD1 CD24 TRIM25 TPD52 FGFR2 PLIN2 DDAH1 HSD17B11 GCNT2 TRIM2 ZWINT SLC5A1 IDH1 SLC39A14 COBL SLC25A1 UPP1 FGFBP1 EPHX2 F2RL1 GNA13 TFCP2L1	0.135094	UP
TANG_SENESCENCE_TP53_TARGETS_UP	C7 COX7A1 ADAMTS5 WFDC1 LCAT CCDC85B GMFG APLP1 ABCA8 BACE1 A2M CLIP1 HBG2 CCND2 ZMAT3 SNCA NRG1 HBG1 RAPGEF4 USF2 MMP3 GABBR2 TFAP4 SIM2 GBX2 IVNS1ABP PSTPIP2 CDKN1A ALDH3A2 VAMP8 TSPAN12 SLC4A4 HSD17B2	0.135443	UP
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	VIP PDE4B RAMP1 PDE2A PDE1A PDE8B GNG11 GNB5 ADRB2 RAMP3 GNG3 ADCY2 GNAI2 GNAZ RAMP2 ADCY7 CALCB PDE4D PTHLH INSL3 HTR6 PDE4C MC1R ADORA2A AVPR2 PDE1B GNG7 POMC CRH ADCY3 LHB AVP TAAR5 IAPP SCT PDE3A PTH1R CALCRL VIPR2 ADCY8 HTR7 CGA ADRB3 GLP1R CRHR2 DRD1 MC3R PTGIR HRH2 GNB3 MC4R MC2R TSHR SCTR LHCGR GIPR PDE10A GNAS ADCYAP1 RLN3 ADCYAP1R1 GLP2R GIP ADM2 TSHB GCGR PTH GNG4 PTGER4 DRD5 FSHR PDE11A GNB1 ADCY1 GNG13 FSHB HTR4 CALCA PDE7B RLN2 P2RY11 GHRHR ADRB1 TAAR2 GNB2 PDE3B PTGER2 GHRH PTH2R GNGT1 GNAI3 ADM GNG5 MC5R ADCY9 VIPR1 ADCY6 GNG12 PDE8A GNAI1 PTGDR GCG ADORA2B	0.135528	UP
ROSS_LEUKEMIA_WITH_MLL_FUSIONS	GPM6B FEZ1 CES1 ZEB2 ITGA7 MEIS1 PBX3 PNMAL1 LPCAT1 LGALS1 IGFBP7 CSPG4 HCLS1 PTPRC PARP8 ANXA5 PALLD RAC2 ZSCAN18 DAB2 HOXA4 SCPEP1 NKG7 CLASP2 PLD3 CCND2 BMI1 KLRK1 MICAL1 LILRA1 ZNF274 RNASE3 MBNL1 ABCA7 DEXI CCL23 HTR1F GLT8D1 CCL5 HIF1A JMJD1C MAP3K5 ARL6IP5 MRPL33 MYH9 FAIM CORO1C ARPC2 POP5 SENP6 SIDT2 C11orf24 ADAM10 CAPG DAD1 PSMD7 ADCY9 HEXB SCP2 HOXA7 HOXA10 ALDH3A2 RHOBTB3 AKR7A2 HOXA5 VLDLR LIPC AK2 DACH1 MYO6 RBKS ENDOG MYO5C HOXA9 PROM1	0.13556	UP
IIZUKA_LIVER_CANCER_PROGRESSION_L1_G1_UP	FOS FERMT2 C1R MRC1 FCN3 IGFBP4 MAF IGFBP3 DNASE1L3 ORM1 PRCP ALB BNIP3L CALM1 ID2 MT3 AMFR MT1H MT1F C6orf120 SLC31A1 AGL RAB14 CPEB3	0.135894	UP
PID_REG_GR_PATHWAY	FOS EGR1 NR4A1 JUN STAT5B MAPK10 BGLAP GATA3 NFATC1 ICAM1 NR3C1 IL6 SPI1 SELE FKBP5 CDK5R1 STAT5A POMC PRKACG SGK1 POU2F1 RELA PBX1 IL13 PRKACA CGA NCOA1 CSF2 KRT17 AKT1 MAPK11 SMARCC2 CSN2 SUMO2 SMARCC1 PPP5C KRT5 CREBBP SMARCD1 TP53 IL5 HSP90AA1 TBX21 MAPK8 AFP MDM2 SMARCA4 PRL NR1I3 STAT1 KRT14 HDAC2 IL2 CREB1 FGG POU1F1 IL4 IFNG TBP SFN NFKB1 YWHAH EP300 HDAC1 IRF1 FKBP4 MAPK9 MAPK3 MAPK14 CDK5 BAX TSG101 GSK3B PRKACB CDKN1A VIPR1 NCOA2 MAPK1 MMP1 PCK2	0.136223	UP
GRADE_COLON_AND_RECTAL_CANCER_DN	TGFBR3 LDB2 CFD FHL1 ITPKB C14orf132 MITF TRPS1 PTPRZ1 JAM3 CHST15 NUDT11 TYRP1 SASH1 PARVB NR3C1 CX3CR1 ZNF135 SIRPB1 B3GALNT1 GPC1 CHST8 CD28 STAT5A MEF2D STAR KRT84 PGC CPN2 SNCA HMGXB4 TLE4 CA5A OSGIN2 FKRP MYCN HAUS5 CCR9 SYNC AOC2 SIX1 CACNA2D2 GNPDA1 CCDC71 LYPD3 HIC2 GFI1 ADAMTSL4 SLC30A3 TIMM22 XPNPEP3 FABP7 PDK4 GGA1 COL4A5 GREB1 GTF3C4 DHPS UBAP1 RERE UNC5B FAN1 LGALS2 SLC30A6 SOCS2 GPR87 DAP SCAMP5 PRKACB TLN2 TM9SF1 CDK12 GNA11 MSRA PARM1 AKR7A2 CBS PLAC8 UGDH PLD1 NR1H4	0.136313	UP
ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN	EGR1 ATF3 PTRF HBA1 ANGPT1 JUN NEFH SLC43A3 LMO2 CXCL2 CREM UCP2 DDIT4 CTSH IER3 APOC1 DNAJB4 CEBPB NLRP1 PTPN7 GP1BB NPRL3 PTP4A3 SLC2A14 MEF2C ETV5 HBZ PIM1 AAK1 KLF1 MOAP1 GTF2I OSGIN1 MCL1 NCOA1 TXNIP FCGR2A KLF6 INSIG1 ATF5 GYPA MAFG ICAM3 ID2 DHX9 NFYA HSPA5 RTN4 HERPUD1 ITGB5 MT2A TAX1BP1 BIRC5 SOCS2 GFI1B ADAM10 FDXR FTH1 IER5 NPL CPOX TXNRD1 FECH AKR1C1 YES1 RPP25 MYB CEBPG SLC27A2 NQO1 HSPA1B	0.137061	UP
REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX	ORC2 CDC6 CDC7 ORC5 PRIM2 ORC4 MCM4 CDT1 ORC1 MCM2 RPA3 POLE2 POLA1 ORC6 MCM7 DBF4 MCM10 RPA1 PRIM1 CDC45 ORC3 CDK2 MCM6 RPA2 POLE MCM5 RPA4 MCM3 POLA2	0.137318	DOWN
NABA_ECM_AFFILIATED	GREM1 ANXA1 SDC2 CLEC3B SEMA3G ANXA6 SEMA3A COLEC12 LGALS1 SDC3 EMCN CSPG4 C1QA CLEC1A C1QTNF3 PLXDC1 PLXNC1 ANXA5 CLEC2B PLXND1 FCN3 C1QTNF1 SEMA4C PLXNB3 COLEC11 FCN1 C1QB SEMA4D SEMA3E GPC1 CLEC10A CLEC7A C1QL1 SFTPC GPC3 CLEC11A SEMA3F SEMA6C SEMA3B MUC6 SEMA4F SEMA3D GPC5 CLEC1B CSPG5 CLEC2D SEMA6B SEMA4A PLXNA3 PLXNA1 CLEC4M SEMA7A LGALS7 CD209 GPC4 SFTPA1 FCN2 CLEC5A LMAN1L MUC16 MBL2 ANXA10 MUC5AC MUC3A SFTPD MUC7 OVGP1 LGALSL HPX LGALS14 CLEC4A ANXA8L1 CLEC4E LGALS13 ANXA9 LMAN1 PLXNB1 ANXA7 PLXDC2 LGALS2 COLEC10 MUC1 PLXNB2 SDC4 SFTPB SEMA6A ANXA2 SEMA4G SEMA3C ANXA11 REG1B MUC13 LGALS3 CLC MUC4 PLXNA2 LGALS8 PARM1 SEMA6D LGALS9 SEMA5A LGALS4 MUC5B ANXA4 REG3A MUC2 SDC1 ANXA3 ANXA13 REG1A	0.137656	UP
HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_DN	DSC2 TOP2A ANXA4 ZWINT TNFSF10 ITGA6 WSB2 CAT LGALS3BP PRKCI C1QBP SCFD1 GRN B4GALT1 SMC3 BCLAF1 CSNK1A1 EIF1AX N4BP1 DSTN KLK7 ECM1 LLGL1 KLK10 HLA-DQA1 HLA-DQB1	0.137884	DOWN
ZHU_CMV_ALL_UP	EGR1 GAL PTGS2 MLLT11 ENO2 NR4A1 NR4A3 PENK TUBB2A FGFR1 OAS2 PDP1 TRIM22 SRF IL7R SLC7A5 IL6 IDO1 IFI6 MX2 NPTX2 TNFAIP3 PIM1 REC8 NFKBIA TFPI2 IFIT1 PML WARS MX1 ISG15 GMPR PLA2G4A EIF5A IL11 STIP1 NPM1 ATF5 GBP1 CSE1L RANBP1 SP100 ITGA8 MSX1 BCL7B UBE2S IFNB1 MANF KDM5C NUP93 PSMC1 TRIM26 IFITM1 SAR1A SNRPB2 PFKP CCL5 PSMB2 SSR1 EIF4A1 CXCL10 SRSF7 EIF1AX POLR2K RB1 PSMD6 TUBA4A SYNGR2 DNAJA1 NUBP1 PSMD2 HSPA1A HLA-E PSMA2 IRF2 LGMN ENO1 NFKB1 RBM14 TAP1 HIST2H2AA3 PSMA6 SNRPA1 IRF1 GTF2B BRCA2 FKBP4 PSMA3 TRIM21 EIF5 CD55 ATP6V1C1 GORASP2 TRIM5 EMP2 B3GNT2 EIF4E RIPK1 PSMB8 HSPE1 IMPA1 GRPEL1 LIG4 MLLT3 GMFB GGCX GCH1 MARK2 PNP IDH3A NAMPT SCARB2 IFI27 SLC39A14 ALAS1 OAS1	0.137959	UP
LEE_LIVER_CANCER_MYC_E2F1_DN	NETO2 REG1A CYP4F2 SLC27A2 RARRES1 PXMP2 OTC PCK1 EPHX2 ABCD3 G6PC C4BPA GOT1 IGFBP2 FABP1 NR1H3 ME1 CPOX ADIPOR2 EGFR ALAD HBP1 OAT TNNC2 ORM2 ACSL1 IL1RAP FABP2 MAT1A CYP2F1 MCM10 SFTPD HAL SLC25A22 BHMT REPS1 CYP2E1 BAAT PNLIPRP1 HPD AASS ORM1 ELANE CTRC CYP7B1 MAPKAPK2 DCT ETNK2 HAO1 APOC4 GHR HSD11B1 RGN RGS16 TRPV2 IGF1 KYNU TDO2 CFHR1 ELOVL5 G0S2 CFH	0.13833	DOWN
CERVERA_SDHB_TARGETS_1_UP	REEP1 PTGER3 FEZ1 MAP1B HTRA1 CAND2 ITIH5 C16orf45 TUBA1A MFAP4 FSTL1 SUSD5 RFTN1 JAM2 OLFML2A COL1A1 SCD5 APLP1 AQP1 PIK3CD ST6GALNAC2 DUSP4 MEGF6 FAM149A SH3BGRL LEFTY2 INHBA HRG GALR2 TNNT1 NOD2 DYRK4 TMEM156 KIF3C GPR68 LYPD1 LOXL2 SPOCK3 SLCO5A1 ST7L TNNI2 KRT17 SCTR SUSD4 MAGEA3 BAAT ASCL1 CER1 TMEM40 PCSK5 MYOF EPS8L1 PMAIP1 MAGEA6 WLS TANC2 SGCB LHX2 CACNB3 SHOX2 PRSS23 PLXDC2 S100A6 SOCS2 ATP6V1C2 FHL2 EMP2 IFIT2 EDN1 RAB20 PLBD1 IGFBP2 LAMC2 SLC25A24 VDR GOLM1 SMPDL3B SLC1A1 KBTBD11 HPSE IL18 ANXA13 ITGB6 UGT2B15	0.139296	UP
PARK_TRETINOIN_RESPONSE	THBD FGR PLEK SLA PIK3CG PIM1 MERTK CEBPE ALOX5AP SMOX SLC2A5 NDRG1	0.139381	UP
FIGUEROA_AML_METHYLATION_CLUSTER_7_UP	GUCY1B3 TUBB6 TGFB1I1 COL21A1 AEBP1 VPREB3 FSTL1 SCG5 MAD1L1 POU2AF1 VWF COCH NNAT IL11RA DNM3 BHLHB9 ZNF667 NRP2 MYO7A CRHBP IFNAR2 KCNAB3 HNRNPD KRT81 NEUROG1 RPRD2 MOS SNRNP70 MAP7D3 CUL9 ZNF174 GP9 SAP30BP FAM131A SPOP MYL4 TLR2 ZNF281 PABPN1 OAZ3 RECQL5 HMHB1 GDF3 DYNC1LI1 MORF4L1 IPO8 PIAS2 BTAF1 HNF4A PFN2 TNPO3 ZFHX2 DBNDD2 N4BP1 PMAIP1 TANC2 SRY HNRNPR CASP2 EDEM1 PPP2CA THRB MRPL9 CCPG1 ZFR ZNF84 ITGAV MT2A ABLIM1 FAM3A MPZL1 OSBPL1A SPHK2 PROSC KDM5B DHRS12 ISCA1 FARP2 CDK8 PIGZ MKKS CANT1 SLC39A14 BTBD3 PAQR5	0.140361	UP
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN	THBS2 ANXA1 FLNA HBB COL5A2 ITGA1 LGALS1 COL6A3 TUBB2A PCOLCE COL1A2 COL16A1 ACTN1 POU2AF1 ARID5B LUM GRB10 RAC2 MAP4 KLF10 TYRO3 PPP1R12A PIK3R3 COL3A1 LYN MNT NOP2 HMGXB4 CUL1 KBTBD2 AGRN CASP4 ATXN10 SIM2 ZNF43 WSB1 ITGB1 MICB PPP2R5C ABCE1 NID2 PFN2 AP3S1 TMEM147 TRAM1 CCT6A PPP2CA ARIH1 PSMB6 CFLAR PSPH KHSRP PSMB5 GSTP1 ENSA ITGAV AHSA1 RTN4 SNX2 POP5 RPP38 HSPD1 ZNF117 PSMA6 ATG12 RCN2 ABR SCARB1 BET1 GLUD1 ARHGEF18 CAPG HARS2 CHD1 GSK3B TBCC PROSC PRKCI HSPE1 LGALS3 SRP54 SEC23A RHOBTB3 CHUK SPR CCDC6 FXYD3 KRT20 DSG2 COL17A1	0.140362	UP
BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN	CTGF THBS2 BHLHE40 MAFF IER3 TRIB1 NAV2 IL4R QSOX1 NCALD VNN3 HPS5 RAB27A LGALS3BP AGPAT2 PLD1 F2RL1	0.140432	UP
REACTOME_DOWNSTREAM_TCR_SIGNALING	LCK HLA-DQA1 HLA-DPA1 TRAT1 HLA-DRB5 CD4 HLA-DRB1 CD3D CD3E HLA-DPB1 CD247 PRKCQ NFKBIA RIPK2 PIK3CA RELA MALT1 IKBKB PIK3R1 IKBKG UBE2N PIK3R2 PDPK1 CD3G TMEM189-UBE2V1 MAP3K7 TAB2 PTEN TRAF6 BCL10 CHUK PIK3CB	0.14057	UP
PID_SMAD2_3NUCLEAR_PATHWAY	FOS ATF3 LAMC1 JUN PIAS3 COL1A2 TGIF2 RUNX3 GATA3 NR3C1 SAP30 CEBPB CBFB MYC SERPINE1 MEF2C RUNX2 AR SKIL TFE3 SIN3B FOXO4 MYOD1 FOXH1 NKX2-5 KAT2A FOXO1 TCF3 RBL1 NCOA1 AKT1 CDK4 IL10 ZBTB17 E2F5 MED15 IRF7 FOXG1 CITED1 MAX IFNB1 CREBBP RBBP7 CDK2 E2F4 DCP1A IL5 ESR1 PIAS4 HNF4A CTBP1 FOXO3 KAT2B SKI RBBP4 ATF2 SNIP1 HDAC2 SAP18 CREB1 HSPA8 SMAD3 ITGB5 RUNX1 SMAD2 EP300 SMAD7 HDAC1 SP3 NCOR1 TFDP1 TGIF1 CDKN2B CDKN1A NCOA2 SMAD4 SP1 VDR	0.140584	UP
MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_UP	C7 ARMCX1 RGS2 FZD7 SCG5 CTNNA2 TMEM204 RBMS3 CPEB1 ZNF423 STOM RUFY3 MAGI2 ENPP2 GALNT11 SATB1 UTRN EIF5A2 KLHL24 MYT1 KDM6B MC4R USE1 LIN7B MAML3 PAH ATP6V0E1 TM7SF2 CPNE3 LRRTM2 CLPB HIST2H2BE CBFA2T2 SERF2 SERINC3 H2AFJ NT5E THNSL1 PDCD4 BRWD1 PPCS RNF170 PBLD HIST1H4H MFSD6	0.140711	UP
KORKOLA_TERATOMA_UP	MGP ARHGDIB CLEC2B PTMS SLC2A3 A2M CLEC7A CCND2 RECQL ITFG2 TNFRSF1A PHB2 ETV6 TAPBPL EMP1	0.140714	UP
GAVIN_FOXP3_TARGETS_CLUSTER_P4	FAM129A STON1 ARHGAP29 SYT11 BACH2 ITIH5 NRP1 CD79B TWSG1 PENK HOPX GPRC5B TIAM1 CD81 TNFRSF9 RAMP3 ALCAM CD83 GGT5 ST3GAL6 TNFRSF1B SWAP70 MMD CDKN2C IL2RA C9orf3 PIM1 MAP3K8 PRKAR1B CTLA4 SEMA4F IL1RL2 IL2RB CAPN3 FOXP3 SEMA4A RAPGEF4 RRAGD FASLG TNFRSF4 ATP8B4 GADD45B STX11 IL1RL1 ACSBG1 MYO1C IKZF2 ENC1 AFP VAV2 ALS2CL PMAIP1 GPLD1 ITGAE OSBPL3 NEB EPAS1 GSTO1 CHD7 FRMD4B GPR15 FAH PDK1 CAPG CTTN VIPR1 PLAGL1 MXD1 ANXA4 NFIL3 MYO10 MBNL3 PRC1 SOAT1 IL1R2 MCTP2 SLC16A5 CNGA1 ADH1C HSPA1B	0.140812	UP
SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP	BCHE TIMP3 CLU CH25H SPOCK1 SLIT2 IGFBP6 SEMA3A CRISPLD2 COL1A2 OAS2 CX3CL1 IFI44L EVI2B IFI44 ALDH1A3 HERC5 PTN IDO1 MX2 NOV NR2F1 IFIT1 DAAM1 MX1 ZFP36L2 ISG15 NDP MAPRE2 HS3ST1 PRR16 RARRES3 TLR4 NMU MAGEA3 GBP1 ISG20 PTGER4 CCL5 CXCL10 MAGEA6 DDX58 ID2 BMP4 ADAM28 HERC6 ZC3HAV1 IFIT3 FAM46A TMEM70 TMEM50A SORL1 PDLIM5 CXCL11 LIPG KLF4 IFIH1 CCNE2 IFIT2 EFNB2 CD24 SAMD9 TFF1 SORD PNP MALL IFI27 DDX60 GPRC5A OAS1 OASL HPSE ABCG2	0.14137	UP
ENGELMANN_CANCER_PROGENITORS_UP	GEM TFPI THBD PMP22 WIPF1 ELOVL5 BASP1 MYO5A LMCD1 SLC7A5 SLC2A6 BAMBI BCL2 SGCG GDPD5 IGFBP3 MAP3K8 FTO ARID4B B4GALNT1 MAST4 GSTM3 DLX2 CYP1A1 RRS1 GALNT6 BYSL PDPK1 KCNN4 CTSZ ANXA9 BZW2 CD55 FHL2 PDCD4 NFE2L2 FAT1 SULT1A1 SFXN1 CDC14B ABCG2	0.14142	UP
WATTEL_AUTONOMOUS_THYROID_ADENOMA_UP	CILP SERPING1 PCSK2 TCEA2 GJA4 ENTPD1 SNAP25 NMNAT2 NPR3 VWF COL4A2 DBN1 CCL18 PRKCB FLRT1 CDH2 GNAO1 TMEM59L KCND2 RAB3A DUSP9 TCFL5 TMC6 TLE6 DLG4 ESM1 TPO CACNA1D PPM1H BMP8A CNTD2 CYP27B1 PARD6A AQP5 ZBTB40 RRP12 ST6GAL1 AKAP17A CKMT2 RAB11FIP4 CPSF3L STX7 DIO1 PDE7B TIAM2 CKB RBBP9 ASCC2 IGFBP1 BIRC5 ALPI MT1H FGFR3 HR ANKH ZNF180 MKI67 QPRT SLC25A15 C3orf52 FCGBP EXPH5 COL17A1	0.141445	UP
REACTOME_SEROTONIN_RECEPTORS	HTR2B HTR2A HTR6 HTR5A HTR1E HTR7 HTR1A HTR1D HTR1F HTR4 HTR2C HTR1B	0.141484	UP
GENTILE_UV_RESPONSE_CLUSTER_D8	ZCCHC24 MN1 RBMS1 IRS1 HEG1 JUN FYN TWIST1 HIVEP2 NR2F2 NACC2 TSPAN5 PARP1 REV3L PPP1R12A LDLR THAP11 INSIG1 RBM15B CBX3 SQLE HNRNPH3 ARHGEF7 SLC7A6 KLHDC3 YY1 TAB2 STK24 MT1X MAPK14 CDYL SPRED2 PPID MARCKS STK38 MET TOP2A EMP1 HMGCR	0.141612	UP
REACTOME_CHROMOSOME_MAINTENANCE	HIST1H2BC HIST1H4H HIST1H2AE HIST1H2BH RFC5 CENPA HIST1H2AC OIP5 HIST1H2BD HIST1H2BG MIS18A HIST1H2BE SYNE2 HIST1H2BI HIST1H2BF LMNB1 CENPN PRIM2 POLD4 HIST1H2AJ RSF1 HIST1H2BM HIST1H4K HIST1H4B RFC2 BRCA1 HIST1H2BK HIST1H4J HIST1H4D HIST1H2AD RPA3 HIST2H2AA3 HIST1H4F POLE2 RFC3 PCNA HJURP SMC1A TEX12 STAG1 H2AFX RUVBL2 SMC3 ATR HIST1H4C ITGB3BP RAD21 HIST1H2BO HIST1H4L TERF2 POLA1 POLD2 HIST2H4A HIST1H4A LIG1 POLD3 HIST2H2BE DKC1 NHP2 MIS18BP1 RBBP4 HIST1H2BB DNA2 FEN1 TERF1 HIST1H2BJ H2AFZ SMARCA5 WRAP53 HIST1H4E RPA1 PRIM1 CENPQ HIST1H4I SYCP1 STAG2 LMNA DIDO1 UBE2I TERT CENPO RBBP7 RPA2 HIST1H2AB TINF2 POLE POLD1 POT1 SYCP2 NPM1 RUVBL1 HIST3H3 SUN2 HIST1H2BN HIST1H2BL CENPI FKBP6 RFC4 REC8 POLA2 ACD TERF2IP STAG3 HSPA2 SYNE1	0.14178	DOWN
AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_DN	PEG10 TFPI CPE PPL HSPG2 PTGS1 CCL20 PTGES AQP3 FOXG1 AIM1L FARP1 KRT13 HR PLAC8 CDA	0.141827	UP
LIU_CMYB_TARGETS_UP	ETFDH NQO1 IMPA2 TMEM30B SATB2 SRD5A1 GDPD3 CASP6 GMCL1 AGAP1 RAB11FIP1 MARCH3 OVOL2 GMNN MYO10 PCTP RBM47 IL17RB TSPAN1 SERINC5 SH2D4A ALDH7A1 STARD5 CA12 ANKRA2 WDR44 PHLPP1 ABCC3 MARK2 PPDPF SOX9 MARCH5 AGA BSPRY FAM134A SLC31A2 LITAF EZH2 TACC2 MPHOSPH9 FABP5 TOB1 ASRGL1 PDK2 KCNS3 ICA1 NAGPA PDCD4 MT1F ACOT7 PYGB MT1E FHL2 TGIF1 FOSL2 SPG11 AKAP1 SAT1 SAC3D1 DLG1 MT1H MT1X MAPK3 CCDC53 ADD3 LNPEP USP25 GLRX KLHDC2 ASS1 YKT6 OAT AK4 HIGD2A MED4 BCR CITED2 NOSIP MT2A EPHX1 DNAJB9 HYOU1 ZER1 MAP1LC3B PEBP1 CDC42EP1 ZNF395 RRM2 CTNS JAG1 PRLR VRK1 ZNF318 SLC10A3 ABTB2 NUMA1 GREB1 BNIP3L TIPARP SPG7 TP53I11 ICAM3 RAB11B STK17A ISG20 CRIM1 INSIG1 EIF5B SLC1A4 RNGTT HPCAL1 PACS2 TNKS2 ECE1 WDR46 NCOA1 GSTM3 NUDT1 PLCXD1 KRT16 CA8 CALML5 DHRS2 LYPD1 PPM1E NUCB2 PXDN PIM2 ARRB2 SLCO3A1 TGFBI DUSP9 ESYT1 ANP32E ISYNA1 IGFBP4 MMD IDS H1FX SAP30 NAB2 ST6GALNAC2 PRAF2 LHX6 CTNNAL1 HSPA12A RPS6KA2 TRPV2 PRKAR2B ARL4C CSGALNACT2 CRISPLD2 DNAJB5 EMP3 EFHD1 SERPINA3 CXCR4 PCOLCE2	0.141953	DOWN
YANG_BREAST_CANCER_ESR1_BULK_DN	DEFB1 ASPM TTK MAP3K13 KCNK5 LAD1 PLIN2 NCK1 ROPN1 GTPBP4 TMEM123 PFKP PLAUR GMPS RIN3 TEX10 LPIN1 APBA2 CEBPB RGS16 DSE SIRPA	0.142063	DOWN
KEGG_GAP_JUNCTION	GUCY1A3 GUCY1B3 TUBB2B TUBB6 ITPR1 TUBA1A PLCB1 TUBB2A HTR2B HTR2A PDGFRB ADCY2 PDGFB GNAI2 PRKCB ADCY7 LPAR1 PDGFC TUBB4A GJA1 TUBB PRKACG PRKCA ITPR2 PRKCG ADCY3 PLCB2 TUBB3 PRKG1 ADCY8 PRKACA GJD2 DRD1 GRM1 TUBA8 GRM5 TUBA1B GNAS TUBA3C TUBA1C DRD2 HRAS ADCY1 TUBB1 MAPK7 TUBB4B PLCB3 GUCY1A2 TUBA4A ADRB1 RAF1 MAP2K1 HTR2C GRB2 PDGFRA PDGFA CSNK1D GNAQ SRC TJP1 MAP2K5 GNAI3 MAP2K2 MAPK3 CDK1 SOS1 PRKX EGF EGFR ADCY9 PRKACB ITPR3 KRAS SOS2 GNA11 MAP3K2 PDGFD PRKG2 MAPK1 ADCY6 PLCB4 GNAI1 NRAS TUBAL3	0.142093	UP
FUKUSHIMA_TNFSF11_TARGETS	NOTCH3 NFATC1 NOTCH4 JAG2 TNFSF11 RBPJ NOTCH1 NOTCH2 DLL3 HEY1 CALCR JAG1 HES1 ACP1	0.142161	UP
BIOCARTA_ATRBRCA_PATHWAY	RAD50 CHEK1 HUS1 FANCF RAD51 BRCA1 CHEK2 BRCA2 MRE11A ATR RAD17 RAD1 FANCC RAD9A FANCE NBN TP53 FANCG TREX1 ATM	0.142306	DOWN
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP	EGR1 AKAP12 MAP1B DUSP1 PRNP JUN CLIC2 ZFP36 GDF15 NAB2 MYC SLC4A7 ACVR1 KLF10 GABARAPL1 MERTK SGK1 MYCT1 RORA AHR DUSP3 TNPO1 NRG1 PGF CLDND1 KLF6 ZCCHC2 SPRY2 HS6ST1 CDC42EP2 TNFSF18 SLC7A11 DIDO1 CCDC82 NCOA3 C15orf39 TIPARP CFLAR RRAGC SQSTM1 HIPK3 ZNF264 AFF4 CLDN15 FOSL2 ANKRD12 PTP4A1 CCNG2 CLIP2 ARHGAP5 RIT1 PANK3 SMG1 EMP1 GCLM	0.142319	UP
PID_FANCONI_PATHWAY	RFC5 RAD50 CHEK1 HUS1 FANCL FANCF RMI1 TOPBP1 HES1 RFC2 BRCA1 BRCA2 MRE11A RFC3 WDR48 FBXW11 H2AFX ATR RAD17 FAN1 FANCI RAD1 PALB2 FANCC RAD9A BRIP1 USP1 FANCE RPA1 TOP3A NBN RPA2 FANCG BLM XRCC3 FANCA RFC4 ATM	0.143441	DOWN
ZHAN_MULTIPLE_MYELOMA_SPIKED	CTGF MAL FBLN2 MS4A1 DUSP2 LTB CCND1 AREG CST6 DSC3 CRYBB1 AZGP1 GNAT1 IFIT3 EDNRB FGFR3 LGALS3BP IFI27 TSPAN7 GALNT3	0.143864	UP
WEBER_METHYLATED_IN_COLON_CANCER	WWTR1 FOXF1 GATA3 TGFB2 SHH PAX6 ALX4 ADAM12 WSCD2 RPS27L DAP	0.143906	UP
CASTELLANO_NRAS_TARGETS_UP	MGP VNN1 CFH CRIP2 PLTP PENK TUBB2A NPR3 KCTD12 IFI16 CX3CL1 ADCY2 SERPINE2 PHLDA3 TMEM43 CRABP2 LSP1 ZNF32 GJA1 LBP CLEC11A IFIT1 ISG15 SARDH DLX5 GBP1 MMP13 IL1RN PQLC3 ITIH2 USP18 ERCC5 STAT1 B2M AK1 PON3 EPHX1 PPP1R7 TAP1 PTX3 CCNG1 IFI35 BAX FNDC3A IFIH1 IL13RA1 PSMB8 LCN2 YIF1A AIM1 ANXA4 ACADM ENPEP MEST SDC1 PERP NQO1	0.144496	UP
KIM_HYPOXIA	ENO2 NKX3-2 BNIP3 JUN ICAM1 IL6 SAP30 ANGPTL4 SERPINE1 IGFBP3 ALDOC PDLIM4 AMPD3 GYS1 PFKP BNIP3L BACH1 VEGFA TPI1 LDHA ALDOA SLC2A1 CCNG2 F3 PLIN2	0.144499	UP
HENDRICKS_SMARCA4_TARGETS_UP	CCL2 MAP1B ITGA5 ATP2B4 EMP3 LGALS1 JUN THY1 ARL4C PDP1 CTSH SERPINE2 MFGE8 FADS3 PTPN7 IGFBP4 TPM1 AHNAK LOXL2 DCBLD2 SMARCA2 IFI30 KRT15 PHLDB1 TEC PSG4 PSG5 LMNA CTSB S100A2 SMARCA4 UBE2H ITGA3 GADD45A PLXNB2 PSG9 ACTN4 EPHB2 MT1H FOSL2 FHL2 CDKN1A FLNB AIM1 ABHD2 KRT18 MMP1 HKDC1 AGT PERP	0.145158	UP
LIU_CDX2_TARGETS_UP	VIL1 ANPEP HOXA9 SI AGR2 KLF5 MUC2 TSPAN1 VDR KRT20 CDX1 ATOH1 HOXA7 HEPH KLF4 DNMT3B JAG1 FABP2 HOXA2 PSEN2 LYZ MSI1 SOX10 SCT IL2RB PGC MUC6 GABRR2 CDX4 FABP6 NPR1 NOTCH4 NPR3 CFD HBEGF NOTCH3	0.146279	DOWN
VARELA_ZMPSTE24_TARGETS_UP	ZBTB16 ATF3 LEPR ADARB1 BTG2 RGS16 DDIT4 TNFRSF1B MYC CYP26A1 CIRBP NCDN BAIAP2 ZFP36L2 CD14 MAPKAPK2 ATF4 TXNIP CUX2 PI4K2A NR1D1 ERF GADD45B C15orf39 MKNK2 SESN1 BCL2L1 CSNK1D GADD45A CRCP GADD45G TIPRL CDKN1A KLF3 SLC20A1 HIST1H1C	0.14661	UP
ZHAN_LATE_DIFFERENTIATION_GENES_UP	CAV2 CAV1 FHL1 EMP3 PECAM1 PAM IGF1 ITGA4 PPT1 CCR2 DUSP5 BCL2 SLC39A6 BMI1 SELPLG ATOX1 MCFD2 RHEB SRSF7 JAG1 BMP6 DYNLT3 P4HA1 HDLBP S100A6 AMPD1 TSPAN3 ARPC1A HEXB CAPN2 ACAT1 PIP5K1B XK	0.146622	UP
REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	IGFBP5 IGF2 IGFBP6 CTSG MMP2 IGFBP4 IGFBP3 PAPPA IGFALS PAPPA2 KLK3 F2 IGFBP1 PLG IGFBP2 MMP1	0.146671	UP
KYNG_RESPONSE_TO_H2O2	CRYAB TGFBR3 CFD AEBP1 MCAM CD81 TSPAN4 PKIA HCFC1R1 ENG GDF15 SRGN IFI6 SERPINH1 MPV17 PTP4A3 FLOT2 TAL1 EID1 OAZ2 PFDN5 RAB36 RELA TCF3 PLXNA1 RPL5 DUT PRKCSH BAG4 CD68 RPL21 RPL31 CKMT2 HNRNPA1 PTGER4 RPL7A CST3 CTSB ATP5E CTNNB1 TUBA4A SLC39A7 DNAJA1 CDC34 CD59 CUX1 RCC1 GADD45A ANKRD1 ZBTB7A TAP1 CCNH ATP6AP1 COX6C DNAJB1 PSMC4 DDX52 ATP6V1C2 PPP1CA UNG CTSS SLC20A1 HMOX1 IL10RB C4BPA CCNA2	0.146767	UP
NAKAMURA_ADIPOGENESIS_LATE_UP	MGP FABP4 ATF3 IGF2 TGFBR3 NID1 G0S2 ELK3 GLT8D2 RAB31 SERPINB9 COL6A3 ITGAM PLK3 PRKAR2B STAT5B NOVA1 CEBPD STOM CYBRD1 MYC MMD CDKN2C CDH13 LIPE LPIN1 TIMP4 GM2A ACACB NPTXR TGFB2 DYM FOXO1 PHKG1 TXNIP USP4 ABCA1 CD36 INSIG1 GAS6 PDE10A TFAP4 COL11A1 MGMT E2F4 TPR IRF9 ZNF24 CTNNB1 ACACA IRS2 ABL1 FASN C19orf24 PTPRA PRSS23 SMARCD2 SUMO1 PPP1CC PUS7L CCNG1 PPP2R5A PPP1CA XYLT1 IGF2R CHCHD3 MRPS6 SMPD1 RDH5 GMFB TNFRSF21 IL22RA1 PSMC6 ACVR2A CKS2 AKAP10 GCC2 PLIN2 PPP2R1B EFNA1 ACSL5 MAPK6 SCD ACSF2 HMGCS1 NFIL3 CCRL2 STX3 MYB PPARG	0.146808	UP
REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	SIKE1 MAVS TRIM25 IFIH1 EP300 TRAF3 DDX58 IKBKE CREBBP IFNB1 TBK1 IRF7 IRF3	0.14698	DOWN
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4	ZBTB16 GEM LMO3 SDPR HSPB8 RBPMS APOD DLC1 EFEMP1 DUSP1 SCRN1 SYNE1 DAAM2 SMARCD3 QKI BLVRA ATP2B4 LPCAT1 ELK3 LIMCH1 HOPX PLS3 SLC16A4 MAP3K6 PIAS3 PER1 ARHGEF10 RPS6KA2 ST3GAL5 ICAM1 FAM184A NAB2 NR3C1 CEP112 ADCY7 FYCO1 CEBPD MR1 LRRC20 STEAP4 SLC7A10 RUFY3 ABCA3 PPP3CC IL27RA NDNF WNK1 ICAM4 VAMP5 ICAM5 SGSM2 ARMC9 NPR1 GALNT11 TROVE2 PBXIP1 REL NAV2 FHOD1 BTG3 NFKBIA ALDH8A1 S100A13 SPTB FGF4 CDKL2 MEGF9 NOS3 ATP11A GNA14 AQP3 MAP1LC3C INPPL1 RHOBTB2 C21orf2 GON4L HDAC5 ZFAND5 RANBP17 CAMTA2 PON1 RIMS3 AASS NINJ2 ALOX15B UNC93B1 DLEC1 ABCA4 CHAT KLHL20 SLC25A16 ZNF451 ALDH3B1 DPY19L1 PSG4 WSB1 MBIP NOTCH2NL ESR1 FOLR1 UBAP2L SFTPD SCEL SLC34A2 AQP4 TIPARP LUZP4 TLE2 EDEM1 EVPL UBAP1 NKX2-1 CLOCK CDC42BPA RAB38 CISH SPINK2 ZER1 SEC24D CACNB1 ATXN7 CHTOP AK1 ATXN2 HAUS4 PON3 EN2 EPHX1 LTA4H ZNF750 CITED2 EPB41L1 LTK ZNF254 ME3 PELI1 EPHX3 APLP2 RAB27A RAPGEF2 BMP3 SFTPB CCNJL PIGA CD55 NEDD4L FTH1 KLHDC10 CYB5A PPP2R3A LPIN2 ARRB1 PRKCD LARP4B CEACAM8 KCNS3 GLS UNC13B CAPN2 ATP8A1 TTC19 PARM1 ALDH5A1 GGCX NEDD9 FAM13A PON2 ERBB2 GPD1L SDHD MAOA HSD17B11 PMM1 MALL TRIM2 NAAA STBD1 FBP1 ITPKA CDS1 AHCYL2 SLC39A8 GPR39 IL6R ABCC6 PSG3 CPM C1orf116 FMO5 CYP2B6	0.147021	UP
DELACROIX_RAR_TARGETS_UP	CTGF NID1 DUSP1 BHLHE40 JUNB CP PLEKHB1 TGFB3 FCN1 CEBPB CRABP2 DUSP6 AOX1 MMP2 MSLN TNFRSF12A LIPE FGF18 RARB SKIL TM4SF1 TCIRG1 ZBP1 ATP11A NUPR1 DMP1 STK11 TYK2 PRSS22 ESD HOXD12 DHRS3 HMGA1 MAST2 SAT1 BLNK MRPL34 TNFRSF11B CHKA PGPEP1 CA12 PRSS8 GSR CAPN5	0.147338	UP
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN	FOS RBMS1 MYC CADM4 C1QL1 BLMH CYP2A13 BRD2 PCF11 FPR2 NF2 MUC3A AP1B1 RHBDF1 KRT7 XRCC6 EIF2AK2 PAXIP1 USP22 USP9X GPAA1 TMEM11 BAX GSS ATP5B	0.147722	UP
ROSS_AML_WITH_AML1_ETO_FUSION	BEX1 CAV1 RUNX1T1 ITPR1 KLF11 WFDC1 ROBO1 TWSG1 RGS10 CD19 LAPTM5 LAT2 LCP1 ARHGEF6 EGFL7 BAALC CD34 IER2 TMEM43 CCND1 RCBTB1 PALM HYAL2 STK32B VAMP5 CIITA PRAME PTPN12 RASA4 TRH PTGIR BAIAP3 TBXA2R VOPP1 POU4F1 ARHGAP1 SLCO4A1 CACNA2D2 ISG20 TCN1 CLEC5A SCML2 NARFL RASAL1 KDM4B C15orf39 IL5RA ADRM1 CD244 AP1B1 SHC1 MKNK2 NCALD USP10 ITGB4 MAN1A1 PELI2 FBXO38 CD58 RPS6KA1 ENDOD1 NIT2 HIST1H2BF HIST1H2BI DEPTOR EPCAM HIST1H2BD TRAF3IP2 SLC25A1 IL17RB HIST1H2BH HPGDS PSD3 ACSM3	0.148128	UP
ABE_VEGFA_TARGETS_2HR	PTGS2 ELAVL4 NR4A1 HBEGF PPL AURKC CD3EAP LDLR APOE DAPK3 CD1B PDCD1 PPY CYP1A1 CDR1 TKTL1 XPO7 BPI EIF1 SERPINB2 RAPGEF1 CARS TNFRSF14 CUX1 HERPUD1 MCM2 RCAN1 CDKN1A PRKCD ZCCHC14 LAD1 UPP1	0.148506	UP
WU_HBX_TARGETS_2_UP	ANPEP UCK2 SLC25A5 CDKN3 FAS YWHAE RAB5C GLRX CCNG1 ATP5J BCL2L1 PDS5B CDC42BPA STK25 HMGB2 MAP2K3 HSPA1L PPP5C CSNK1G2 CASP4 TGFB2 CXCL1	0.148853	DOWN
FRASOR_TAMOXIFEN_RESPONSE_DN	ABAT SOX9 GCSH PDCD4 MYLIP EHD4 DNAJC12 NAT9 STS GALNT6 MEGF9	0.148879	DOWN
GAVIN_FOXP3_TARGETS_CLUSTER_P6	PBK ASPM TMEM38B HMMR SLC39A4 NEK2 CCNA2 CEP55 IL17RB AURKA CCNB1 KIF20A CDC20 ABCB1 CCNB2 TPX2 SPC25 BUB1B CENPF CKS1B LGALS3 CENPE RAD51 NUSAP1 KIF2C KIAA0101 ACOT7 GINS2 CDCA8 ALAD CDK1 TYMS TK1 NCAPG BIRC5 NCAPG2 TPI1 ABHD4 SPAG5 AURKB BUB1 RRM2 CDCA3 ATF6 PDCD1LG2 PLK1 CYSLTR2 DCTD GZMB MCM10 IL12RB1 RAD54L RPL17 TKTL1 GEMIN8 CST7 UNC119 CLSPN IGF2BP3 KSR1 IRF8 ODC1 AR MTMR7 BMP7 MYO1F TGFBR2 CCR2 RASGRP2 ICAM1 NEDD4 IFI44 TNFRSF9 EBI3 NRN1	0.1489	DOWN
SANA_TNF_SIGNALING_UP	CCL2 RHOB CCL11 VCAM1 SLC15A3 CXCL2 OAS2 TNFAIP2 CX3CL1 C1S IFI44L BST2 PLA1A SSPN IL7R ICAM1 DRAM1 APOL3 C1QTNF1 SAMHD1 MX2 TNFAIP3 CCL20 SERPINE1 INHBA UBD NFKBIA IFIT1 RIPK2 MX1 APOL1 BIRC3 CSF1 IFI30 BPGM MMP3 TLR2 RAC3 GBP1 SLC7A2 CXCL3 ICOSLG CXCL10 MMP10 CCL8 TAPBP CCL7 OAS3 DNAJA1 ITGAV SMAD3 HLA-C HLA-B HLA-A IL32 RABL3 CXCL11 SAT1 LIPG FTH1 SOD2 TNIP1 CXCL6 IFIH1 LGALS3BP CASP1 ATP13A3 LGALS9 HSD17B11 OXR1 DDX60 LAMB3 SPAG9 OAS1	0.148949	UP
ELVIDGE_HYPOXIA_DN	NETO2 SCYL2 GDPD3 GNA13 SPAG1 CA2 TMEM33 STX3 CEBPA SORT1 RPP25 CDC20 MAPK1 ZWILCH ADAT1 IDH3A LRRC59 MRPS12 GLUD2 ATP6V0A2 RNF14 NCLN CHUK CHKA IDE GCH1 PPIF BAK1 NR2F6 SLC35B1 NIP7 ZMPSTE24 CENPN LARS2 TMEM50B CORO1B CYB561 ACOT7 COPA SLC35C1 GLYR1 AMD1 SLC25A44 ABCF2 SEC23IP NDUFS6 FASTKD5 RRP15 FKBP4 SOCS2 LARP4 TOMM22 HSPA4 SUMO3 QRSL1 PRPF4B POLR3E BRMS1 GULP1 PSME3 DHX29 GPS1 GPATCH2 SRSF1 ATP2A3 HSPH1 EXOSC4 WDR77 DNAJA1 SLC7A6 FLAD1 DCTN5 C18orf8 JAK2 SLC5A6 KPNA1 OGDH DDX3X HNRNPH1 SPDEF CALM1 URB2 ARHGDIA DOLK TOR3A POLR3K ALDH4A1 RAB35 MAZ KPNA4 ESR1 ETF1 PSEN2 PUS1 ARPC4 GAS2L1 SDF2L1 RANGAP1 CDV3 PYCRL NUP98 C6orf106 PNO1 SNRNP40 OSTM1 CCDC86 RNASEH1 EEF1E1 ASPSCR1 BOP1 ADORA1 STIP1 FUS EIF5A MAPKAPK2 HSF1 CCND3 C14orf169 ODC1 KLC2 ELMO2 KIAA0930 PIK3R3 PDZK1 SLCO3A1 C2CD2 GYG1 AOX1 TAF9B RET SRM TFAP2C SLC29A1 HHEX CORO1A SLC24A3 CXCL12 SOBP	0.149147	DOWN
REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	SLC35A3 SLC35A2 SLC28A2 SLC35D2 SLC35D1 SLC33A1 SLC35A1 SLCO4C1 SLCO1B3 SLC35C1 SLC29A2 SLCO1C1 SLC5A6 SLCO2A1 SLC29A3 ALB SLCO2B1 SLC28A1 SLCO4A1 SLCO1A2 SLC28A3 AVP SLCO1B1 SLCO3A1 SLC27A6 SLC29A1	0.14931	DOWN
ROVERSI_GLIOMA_COPY_NUMBER_DN	FHL5 CES1 ZEB2 ITIH5 KCNMA1 ARHGAP15 KYNU GNAO1 CETP POU3F2 TUBGCP3 CDKN2A LRP1B SFTPA1 UROS GPR63 ARL2BP ITIH2 CTBP2 ADAM12 SFTPD ING1 PRDM13 ARHGEF7 SOX1 ANKRD10 FAM192A HERPUD1 BCCIP PTEN COQ3 DOCK1 AMFR PTPRE DHX32 ATP5C1 CCNC ANXA11 NUDT21 KIN MKI67 HNMT FBXL4	0.149381	UP
GHANDHI_BYSTANDER_IRRADIATION_UP	PTGS2 IL33 C8orf4 BCL2A1 CD69 G0S2 CXCL2 FGF2 MCTP1 KYNU PTGFR DUSP2 TESC CREB5 IL7R RGS9 ICAM1 IRAK3 HSD11B1 DNAJB4 STC1 CXCL1 DUSP5 TNFAIP3 SLC16A6 INHBA PTGES GPR68 AHR IL1B SLC6A15 BIRC3 PLA2G4A OSGIN2 MMP3 PHEX CCK CXCL3 SLC7A11 SERPINB2 CXCL10 LIF MMP10 CXCL5 RELB IL1A POPDC3 GADD45G IL13RA2 SLC16A3 ZCCHC6 MT1X MT1H MT1G SAT1 ATP6V1C1 MT1E SOD2 LRRC8B GCH1 NAMPT SLC39A14 MMP1 LAMB3 SLC39A8 EPB41L4B GCLM MCTP2 PLEK2 RNF128	0.149473	UP
BIOCARTA_MYOSIN_PATHWAY	PPP1R12B PLCB1 ARHGEF3 MYLK PKN1 ARHGEF4 ARHGEF10 ARHGEF6 PRKCB ARHGEF17 ARHGEF15 GNA12 PRKCA ARHGEF1 MYL7 ARHGEF2 MYL2 ROCK1 ARHGEF9 GNB1 ARHGEF7 GNGT1 GNAQ ARHGEF11 ARHGEF18 ARHGEF12 ARHGEF16 ARHGAP5 ARHGEF5 GNA13	0.149483	UP
ONDER_CDH1_TARGETS_1_UP	ZBTB16 ATF3 TSC22D3 CRIP2 CYP1B1 LEPR CSRP2 KCNMA1 TCEA2 EFEMP2 GPX3 OBSL1 PAMR1 TGFB1 BCL6 PHGDH FAM117A LAPTM5 PER1 BTG2 EFS LTB INPP5D HCFC1R1 GDF15 LHX6 MAGED2 DLGAP4 RRAS H1FX CD44 CELSR2 GPC1 DBP PTGS1 CADM4 C1QL1 PNRC1 STC2 GABARAPL1 NINJ1 SEMA3F CD70 HERC1 PRKCA APOE ZMAT3 NR1D2 KLF9 NUPR1 KLHL24 PPFIBP1 CRELD1 FBXO2 TXNIP CEP152 HSPA13 ALOX15B CHAC1 POMZP3 BTN3A3 ZNF451 C9orf16 ASNS PER2 GOLGA2 MST1 YIPF2 DIDO1 BHLHE41 MDM2 N4BP2L2 SSBP1 ZNF516 EPHB3 CDKN1B SLC39A7 IL1RAP MAGED1 ZMYM2 TMEM214 SEC24D ZNF226 FTL DNAJB9 PAN2 CCNA1 THSD4 MMP28 EPHX1 ZNF750 SENP6 RRNAD1 ZNF184 ABHD4 LRP5 KDELR3 EML2 METTL7A ANG PRKAG2 PGM3 PDE4DIP CD55 GCLC RNASE4 BLNK EGFR CTTN PDCD6 IL15 KHNYN AKR1C1 TMEM187 GOLGA4 FBN2 AKR1C2 ABCG1 IGFBP2 ALDH6A1 PRSS8 PCK2 CALML4 WIPI1 GFPT1 CYP4F3 CYP4F11 PRSS16 AKR1C3 AKR1B10 CTH	0.149598	UP
SCHLOSSER_SERUM_RESPONSE_UP	EGR1 REEP1 FLNA PCOLCE FGFR1 MAPT ARHGAP25 MAP4K4 LTB RAMP2 CEP68 CBFA2T3 CRABP2 ADA INSL3 ST3GAL1 BCL2 ERCC2 PDE4C IFNA4 SMAD9 SIPA1 SFTPC FOXA2 ACAP1 GPSM3 PLEKHM2 KIF1A S1PR4 CCNI IFNA16 JUND ORAI2 KCNB1 GRAMD1B KLF12 CHD8 TNPO1 RAD51D ARHGEF2 RELA NKX2-5 RPRD2 MYO9B UPK1A IL2RG L3MBTL1 ELL2 POU2F2 S100A11 MXD4 BRD2 CRHR2 RHOG SPTAN1 PIGQ USP4 KIFC1 CD99 CSNK1G2 NME3 TRADD CACNA1A HOXC5 WNT7A PTPRS CNOT3 PI4KB TNRC6B ARPC4 TYK2 PTK2B ICAM3 SNTB2 CSK PTPN1 STX16 KDM4B STAT3 GNAT2 CDK10 N4BP2L2 CDKL1 PITPNM1 PDPK1 CEP350 SPDEF STAT6 TAPBP BTF3 CCDC94 MAP3K11 GNB2 TNNI1 ALDH3B2 HTT UBA1 DEPDC5 ARHGAP35 AP1S1 WIPF2 DOT1L MAP3K7 ZBTB7A PCYT1A SNX1 PPP1R11 CYBA IRF1 BRCA2 ACTN4 PPP4C GAB1 SCAP KIF3B RAB5C CAPG RALY DCAF7 OCEL1 ZNF91 TRANK1 NR2F6 STXBP2 ZFY ATP6V0D1 SLC9A3R1	0.149742	UP
ZHENG_FOXP3_TARGETS_UP	NRP1 RHOH PRKCH CREM ICOS CD44 IL2RA PRDM1 MAP3K8 CTLA4 FAM46C IKZF2 IFNGR1 COBLL1 P4HA1 FRMD4B ABCB1 IRF6	0.149992	UP
STEARMAN_TUMOR_FIELD_EFFECT_UP	LPL SPP1 CD200 LAPTM5 SIRPA CSF2RB CTSK APOC1 SOCS3 PTGS1 NOV ITGAX PLD3 ITIH4 MYO7A ACP5 SERPINA10 CHI3L1 CD68 CLEC4A F7 CTSZ IQGAP1 SAT1 LCN2 CTSD LY75 CSTB CTSS SCARB2	0.150038	UP
REACTOME_TIGHT_JUNCTION_INTERACTIONS	MPP5 CLDN7 F11R CLDN4 CLDN8 CLDN3 PRKCI CLDN15 CLDN1 PARD3 CLDN18 PARD6B CLDN16 CLDN14 PARD6A CLDN6 CLDN9 CLDN17 CLDN11 CLDN10 CLDN5	0.150168	DOWN
RODRIGUES_NTN1_AND_DCC_TARGETS	FOS EGR1 CDKN1C ARHGEF3 MMD PDE4C KLF10 KLF9 MSX2 MAML3 BCL3 RAB26 TBC1D4 ETS2 PIK3C2A MT2A H2AFY SNX5 MT1X MT1E MT1F NF1 PPARA ELF3 KIF13B AKAP10 ITGA2 CDH17	0.150619	UP
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP	SYNM CTGF ZBTB16 TAGLN NRN1 PPP1R3C CAV1 PDE4B PLTP RPRM PDE2A BHLHE40 BNIP3 AKAP2 NME4 CD81 TMEM45A BTG2 VWF LRRC32 DDIT4 DAPK1 SERPINE2 PITPNC1 IER3 PHLDA3 JAG2 SLC2A3 KANK3 SAP30 A2M ANO3 AEN RHBDF2 ZAK WNK1 SLC19A2 IFITM3 GALK1 PTP4A3 STC2 PTPN14 PIK3IP1 ZNF365 DYRK3 PTK7 PHLDA1 ZMAT3 FSD1 CCP110 NPM3 ETV4 RNF19A ASCL2 GRIP1 FAM114A2 DEF6 GLUL LRRFIP1 EIF4EBP1 MNAT1 POM121 SIVA1 TMEM143 CHAC1 SUSD4 LAGE3 TFAP4 DDX3Y SRRM2 PQLC3 SLC6A14 FABP7 PFKP ZNF688 RPS12 HSPBP1 LUC7L2 CGREF1 GNB1 RPL34 MDM2 N4BP1 ATP5E COMMD3 RAP2A RAP2B FOXO3 PMAIP1 BNIP3L PRRC2C SNRPG RB1 NPPB LSM7 PIGP NR6A1 P4HA1 CDC34 BOLA2 AK1 PLEKHA2 GLRX3 LLPH MT2A TCP1 CXorf40A MAPKAPK3 TIMM8B TAP1 PRMT5 MTG1 ABHD4 PIGF PDK1 CCNG1 ARAP2 SOSTDC1 PFKL ADM DPM3 PGK1 NDUFA7 RAB5C HPRT1 COX7A2 EI24 RALY CCNC MFAP3 KDM5D WNT6 CDKN1A LMNB1 FAT1 PSRC1 FAM162A UBE2K HOXD4 DUS4L P4HA2 GBE1 VLDLR ST14 HIGD1A NDRG1 APAF1 DCXR NAMPT CA12 CLCN3 PGM1 KRT19 PLOD2 UPP1 HK2 HOXB9 EGLN3 WIPI1 PERP KBTBD11 HOXD1 EGLN1	0.151001	UP
GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_UP	PTPRZ1 NES PCSK1N CELSR2 CRMP1 MAP2 CCND2 CSPG5 GRIA2 SHC3 DLL3 METRN OLIG2	0.151143	UP
FIGUEROA_AML_METHYLATION_CLUSTER_3_DN	AHNAK2 PPP1R15A ARHGAP10 PLEKHA4 CRTC3 EPHA2 PLEK AHNAK TLR1 NOS3 C12orf10 SEZ6L PHLDB1 GPR17 KDM4B RHOT1 NECAP2 HIST1H2BJ MAML1 EIF3A MED25 TSFM ARF6 PPARD HIST1H2AG TMEM33	0.151205	UP
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM	CLU FN1 SPP1 TNXB VCAM1 COL1A1 CP IGFBP7 ACTC1 VIM CX3CL1 BGN COL18A1 A2M EEF1A2 IGFBP4 TUBB KCTD7 VCL C2 AHSG TPM3 RAN RPL10A EEF2 TUBA1C ACTB HMGB1 TF PPIB TPT1 ARHGDIA VCP GLO1 PEBP1 SERPINC1 CTSZ CLSTN1 SRSF2 YWHAZ GAPDH PCNA PRDX1 ENO1 ALDH3A1 TPI1 CFB SERPINB6 SDC4 LDHA ALDOA TKT ALAD YWHAE LGALS3BP CTSD CTSA MDH2 GOT1 CDH1 PHACTR4 ANXA3	0.151547	UP
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_CIS	PADI2 PTPRF ACAA1 MRPL35 MTIF2 PDXDC1 ARL6IP1 MRPL44 TUBGCP4 OCEL1 PRDX2 ALAD NDUFA7 MRPS7 DDA1 CTSC ALDH9A1 SRP9 GFER IQGAP1 TOX4 CUX1 GATAD2A NOP10 DAP3 SKP1 PSMB6 VPS52 CLEC16A GLO1 THUMPD1 NECAP2 TCEB3 SPG21 GNB1 PRKCE DCTN6 SNRPB2 KCNJ9 HARS ACADL ZFAND5 MED1 FAM114A2 TRMT1 MYO7A CCND2 KLC1	0.152149	DOWN
TSENG_IRS1_TARGETS_UP	MGP SRPX FERMT2 CH25H SERPING1 SDC2 FHL1 SPP1 LAMA4 HSPB2 TNFAIP2 IGF1 DBN1 NNAT FAP TCF7 CRABP2 NDN MAPK12 COL7A1 NR2F1 MTHFD2 MEF2C C9orf3 LDLR GLRB RPL39L MYBL2 TRIB3 TES B4GALNT1 NDE1 SLC3A2 SIGLEC1 DDIT3 NUPR1 MID1IP1 NOP56 ZNF22 DDX18 AGTR2 CYHR1 GBP2 BPGM GJB3 NMT1 WISP1 YARS ASNS IARS ST13 TSHB RCL1 HSP90AA1 ACLY DDX47 SQLE SLC35C2 FEN1 PPIH CARS XRCC6 DCTN5 GRB2 RUFY1 ACTR3 BMP6 DLK1 SF3A1 PDGFA BUB1 PRSS23 HSPA4 CYBA COPS5 ACTN4 PCYT2 HSPA9 NARS KIAA0101 RNF6 ARF3 CDKN2B ZDHHC6 EFNB2 WNT5A TMEM97 PHB CD24 FBN2 PTPRF C2orf47 SLC9A3R1 UCK2 GCG ADORA2B	0.152845	UP
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP	PLN SDPR PCOLCE2 CD69 PCDH9 PBX3 SERPINI1 LIMCH1 MS4A4A EVI2A PTPN13 TYRP1 MCTP1 PLCL1 PCDH17 GLIPR1 IL7R TOX HOXA4 KMO NME7 FKBP5 FAM198B FLT3 MMP7 SCN2A CA8 CALCRL PLA2G4A STAT4 DLX2 GPR21 HOXA3 HOXC6 TEX15 HOXB3 MSX1 CRIM1 LPAR6 IFNB1 ITGB8 STK4 XCL1 USP32 SLC25A36 CDH9 SYBU PDE4DIP S100A10 SLCO4C1 SEMA3C DMXL2 SCML1 EDN1 MECOM HOXA5 TSPAN12 DACH1 INPP4B HPGD KLF5 GNAI1 DHRS9 CEP70 C5orf30 HOXA9 IL18	0.153579	UP
REACTOME_SIGNALING_BY_PDGF	THBS2 NR4A1 THBS4 AKT3 SPP1 PDE1A COL5A2 COL6A3 COL4A1 COL1A1 COL6A2 COL1A2 COL4A2 PRKAR2B STAT5B COL6A1 PDGFRB ADCY2 PDGFB ADCY7 COL5A1 PDGFC THBS3 COL9A3 PLCG1 PDE1B STAT5A COL3A1 PRKACG PRKCA ITPR2 PRKAR1B PRKCG PIK3CA FOXO4 ADCY3 TRIB3 PRKAR1A COL9A2 COL9A1 ADCY8 FOXO1 PRKACA AKT2 COL2A1 AKT1 PIK3R1 FURIN GSK3A COL4A4 MAPKAP1 MTOR CAMK4 RPS6KB2 PRKCE RAPGEF1 STAT3 HRAS PIK3R2 MDM2 ADCY1 COL4A5 FOXO3 PDPK1 CALM1 NCK2 STAT6 RAF1 MAP2K1 STAT1 GRB2 CDKN1B CALM3 PDGFRA CALM2 CREB1 TSC2 COL4A3 CASP9 PDGFA RASA1 SRC PRKAR2A PLG PLAT MLST8 YWHAB PTEN THBS1 BAD MAP2K2 MAPK3 CRKL CDK1 SOS1 CRK ADCY9 PRKACB ITPR3 KRAS CDKN1A PRKCD PDGFD NCK1 CHUK PIK3CB PHLPP1 MAPK1 ADCY6 GRB7 NRAS	0.153701	UP
SCHURINGA_STAT5A_TARGETS_DN	CXCR4 BCL6 CD48 PECAM1 CTSG TYROBP CD44 MYCN ELANE MPO FOSL2 CASP1 AIM1 CEBPA	0.154081	UP
REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE	SYT1 STXBP1 SNAP25 VAMP2 RIMS1 RAB3A SLC38A2 SLC17A7 STX1A GLS2 SLC1A6 SLC1A7 GLS UNC13B SLC1A1	0.154103	UP
GEISS_RESPONSE_TO_DSRNA_UP	ATF3 ANXA1 IGFBP6 BNIP3 CHN1 TNFAIP2 FGF2 CCL4 CD44 TNFAIP6 TNFAIP3 NFKBIA TFPI2 IFIT1 AFAP1 TRAF1 EIF2S3 PLAUR GBP1 XPO1 BTN3A3 ADAR HMGB2 CFLAR TAP1 IRF1 ACSL3 PSMA3 BIRC2 NMI SAT1 KLF4 SUOX ELF3 GCH1 IQGAP2	0.154122	UP
ST_GRANULE_CELL_SURVIVAL_PATHWAY	FOS ITPKB JUN CXCL2 MAPK10 CREB5 MAPK8IP2 PARP1 MAPK8IP1 CAMP CXCR2 MAP2K7 MAPK8IP3 MAPK8 DAG1 CERK ASAH1 CREB1 GNAQ CREB3 EPHB2 MAPK9 MAP2K4 APC MAPK1 ITPKA CASP3	0.154393	UP
MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_DN	PDLIM3 INA PPL RARRES2 CDC42EP3 OXTR WIF1 ALDH1A1 ASS1 FUCA1 VAMP8	0.154566	UP
APPIERTO_RESPONSE_TO_FENRETINIDE_DN	SLC3A1 ARFGEF2 DHFR MDH2 CYB5B MON1B ATP5B RSU1 C11orf49 MTX2 PTCD3 IARS2 NDUFC1 EGFR MBOAT7 ATP5J2 PGK1 UQCR10 NDUFA2 LDHA ATP5O MDH1 PPP1CC SIGMAR1 FCGR1A HIST1H4C TMSB4X PPIH UGGT2 H2AFZ PTMA EIF3F SERPINB2 PSAT1 SLC4A5 ISCU ASNS SET BANF1 TRIM28 COL3A1 ARMC9 IFITM3 IFITM2 FMNL1 FLI1	0.154605	DOWN
DUAN_PRDM5_TARGETS	ENO2 EDNRA ISLR DKK3 PPP1R12B PAX5 PHC1 EVL PIAS3 PALM2-AKAP2 CACNA1C SOCS3 MYC RUNX2 NAV2 NOTCH1 PML NOTCH2 WNT10B INTS3 SOX2 ADARB2 GCK GPR1 CD99 ARID3B PAX6 CDH4 RXRB ALX4 PSG1 COL19A1 GADD45B TP53 RARA ACSBG1 CLDN16 PPIL2 EMID1 CKLF CLK3 POU5F1 S100A2 TINAGL1 ID2 MYOM2 E2F3 CCDC33 CDC42EP4 ETS2 RUNX1 EED CYP3A7 POU2F3 MYD88 GABPA OVOL1 IL6R MYB APOBEC3B	0.154618	UP
REACTOME_MEIOSIS	HIST1H2BC HIST1H4H HIST1H3H HIST1H3D HIST1H2AE HIST1H2BH HIST1H2AC RAD50 HIST1H2BD HIST1H2BG RBBP8 HIST1H2BE SYNE2 HIST1H2BI HIST1H2BF LMNB1 RAD51 HIST1H3E HIST1H2AJ HIST1H2BM HIST1H4K HIST1H4B MLH3 HIST1H3A HIST1H3F BRCA1 HIST1H2BK HIST1H4J BRCA2 HIST1H4D HIST1H2AD RPA3 HIST2H2AA3 HIST1H4F MRE11A HIST1H3B MSH5 H3F3A SMC1A TEX12 STAG1 H2AFX SMC3 ATR HIST1H4C RAD21 HIST1H2BO HIST1H4L TERF2 HIST2H4A HIST1H4A HIST2H2BE HIST1H3G HIST1H2BB TERF1 HIST1H2BJ H2AFZ HIST1H4E RPA1 HIST1H4I SYCP1 STAG2 LMNA MLH1 DIDO1 UBE2I TOP3A NBN CDK2 RPA2 HIST1H2AB TINF2 HIST1H3I HIST1H3C SPO11 POT1 DMC1 BLM TEX15 SYCP2 H3F3B CDK4 HIST3H3 PRDM9 MSH4 SUN2 HIST1H2BN HIST1H2BL HIST1H3J FKBP6 REC8 ACD RAD51C TERF2IP ATM STAG3 HSPA2 SYNE1	0.154991	DOWN
REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A	MAD2L1 NEK2 CDC20 BUB1B CDC23 UBE2D1 UBE2C UBE2E1 BUB3 CDC27 ANAPC5 ANAPC1 CDC16 RPS27A UBA52 ANAPC10 ANAPC2	0.155413	DOWN
TOMLINS_PROSTATE_CANCER_UP	AMACR BDH1 CXADR UGDH MYO6 KRT18 MCCC2 ZNF217 HSD17B4 UAP1 PAICS SOX4 CAMKK2 RAB11A GUSB PDLIM5 F2R MBOAT2 PARG CANX SLC25A6 SEC16A CNPY2 DKC1 PPIB EIF4A1 RPL31 EEF2 ZNF652 ATP6V1G1 NACA MANF SND1 CACNA1D TRIM27 BICD1 DAPK1 ERG GUCY1A3	0.155438	DOWN
KEGG_NON_HOMOLOGOUS_END_JOINING	RAD50 NHEJ1 XRCC4 LIG4 MRE11A PRKDC XRCC6 FEN1 XRCC5 DNTT POLL DCLRE1C POLM	0.155808	DOWN
REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	CYP2B6 CYP2C18 CYP4F2 CYP4F11 CYP2J2 CYP4F3 CYP2C9 CYP51A1 CYP3A5 CYP3A43 CYP2D6 CYP27A1 CYP4F12 CYP3A4 CYP3A7 CYP24A1 CYP2R1 CYP2C8 CYP4F8 CYP17A1 CYP2F1 CYP19A1 CYP39A1 CYP4A11 CYP11A1 CYP2C19 CYP2E1 CYP27B1 CYP7A1 CYP2A6 CYP1A2 CYP1A1 CYP7B1 CYP11B2 CYP2W1 CYP2A13 CYP11B1 CYP26B1 POMC CYP26A1 TBXAS1 CYP4B1 CYP21A2 CYP46A1 CYP1B1 PTGIS	0.155861	DOWN
REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS	SDC2 DCN SDC3 CSPG4 BGN GPC1 HSPG2 GPC3 GPC5 B3GAT3 AGRN B3GAT1 GPC4 BCAN VCAN B4GALT7 NCAN SDC4 SDC1	0.156113	UP
REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM	PPCDC PANK3 PPCS COASY PANK2 AASDHPPT PANK4 FASN SLC5A6 SLC25A16	0.156129	DOWN
REACTOME_SPHINGOLIPID_METABOLISM	GBA3 ARSE GALC SGPP1 NEU1 GLB1 CTSA SGPL1 SPTLC1 CERS6 GBA SMPD1 HEXB VAPB SMPD3 OSBP SPTLC2 SPHK2 VAPA SMPD2 GLA GAL3ST1 HEXA ASAH1 CERK KDSR COL4A3BP CERS2 UGCG ARSF ARSA PSAP NEU3 STS CSNK1G2 ARSB NEU2 SMPD4 GM2A SPHK1 ARSJ SGMS1 CERS4 DEGS1 PRKD1	0.156329	DOWN
ZEMBUTSU_SENSITIVITY_TO_VINBLASTINE	HSD17B2 GJB1 ANXA4 CKS2 MYH14 PDIA4 INSIG2 CUX1 MYO15B SPTBN1 PABPC1 HNF4A ITIH2 RNASET2 UCP3 LPP NR3C1	0.156389	DOWN
BIOCARTA_CASPASE_PATHWAY	CASP7 CASP6 CASP3 APAF1 XIAP CASP1 CYCS LMNB1 BIRC2 CASP8 CASP10 DFFB CASP9 LMNB2 CASP2 GZMB LMNA PRF1 CASP4 DFFA BIRC3 PARP1 ARHGDIB	0.156714	DOWN
KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM	GFPT1 ASL ABAT GOT1 GLUD2 GPT ADSS ALDH5A1 NIT2 GLS GLUD1 ASS1 GAD2 GOT2 DDO GAD1 ALDH4A1 ADSL ASNS CAD CPS1 GLS2 GLUL PPAT AGXT ASPA GFPT2	0.156816	DOWN
KEGG_GLYCOLYSIS_GLUCONEOGENESIS	ADH1C ADH6 PCK1 PCK2 G6PC HK2 PGM1 DLAT ALDH7A1 FBP1 ADH1A ALDOB DLD ALDH3A2 PDHA1 ALDH2 GPI ALDOA PGK1 AKR1A1 PFKL LDHA ALDH9A1 TPI1 PDHA2 ALDH3A1 LDHC ENO1 GAPDH ALDH3B2 PDHB ADH5 LDHAL6B PGAM1 ALDH1B1 ADH7 PGK2 PFKP FBP2 HK3 ALDH3B1 PKLR HK1 BPGM G6PC2 PGAM2 GCK LDHB ALDOC PFKM ENO3 ALDH1A3 ENO2 ADH1B	0.156846	DOWN
VANTVEER_BREAST_CANCER_ESR1_UP	FOXA1 ACADSB NAT1 ERBB3 APPL2 C5orf30 TFF3 MYB VAV3 ABAT OVOL2 MREG MYO5C RBM47 KRT18 MCCC2 FBP1 CA12 SLC9A3R1 ECI1 HMGCL PCSK6 KCTD3 FAM179B GPD1L BTD KIF13B FARP2 HSD17B4 RNF103 SCUBE2 CERS6 KIF16B FAAH PEX19 FAM63A SLC35E2B TSPAN13 PIGT CCNG2 INPP5J LRBA TMBIM6 NEDD4L MYLIP CHAD BAG1 EML2 SCCPDH COX6C TMBIM4 QDPR XBP1 SNX1 HEXIM1 AQR TPBG BRD8 KIAA0141 GADD45G MAN2B2 SYBU PPP1R26 FAM134B PTP4A2 FAN1 AFF1 IGBP1 HTT HHAT SKP1 CISH CERS2 HDAC11 MRPS27 BTF3 ZNF587 SPDEF UGCG GREB1 ITPK1 P4HTM DBNDD2 SCAMP1 KIAA0232 FAM102A KDM4B DNAJC12 ESR1 HNRNPA1 TUSC2 SREBF1 RARA MED13L ZBTB40 REEP5 C9orf116 CHRD ERBB4 PTPRT SPEF1 SEC14L2 FAM174B PBX1 MAST4 FUT8 CAMLG TBC1D9 NPDC1 DNALI1 NEK9 LZTFL1 CELSR1 CYB5R1 GFRA1 CIRBP RAB11FIP3 IL6ST WDR6 LRIG1 C3orf18 SLC16A6 SLC39A6 SYNGR1 BCL2 IGFBP4 GPR162 ABCA3 C4A GLI3 SOX12 MAGED2 CCDC106 GATA3 EVL TCEAL1 ELOVL5 IRS1 BHLHE40 LAMB2	0.157027	DOWN
CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_UP	LRRC31 SRD5A1 PTK6 LAMB3 COBL PRSS8 CHN2 POR CLDN3 CROT DHRS1 FCGRT ICA1 PEPD CLDN15 PRKAG2 DAO EPHA1 GARNL3 CIDEB MNS1 POLD2 TLE2 PFKFB1 CYP2A7 ADCY1 ELAVL1 CRYAA CLDN14 GCGR SLC28A1 HAAO MAGEB2 GPR88 POT1 PILRB CHAC1 CYP2A6 ARMC6 SLC22A1 MPPED1 PEMT RAPGEF4 FBXO2 IGFALS GCK FOLH1 ANO1 PYGL TM6SF2 ABCB4 SLC16A2 MAD1L1	0.157092	DOWN
NAKAMURA_LUNG_CANCER_DIFFERENTIATION_MARKERS	RFTN1 CLDN5 RARRES2 SFTPC IQCG FABP6 DNAI2 HIGD1B DNAAF1 SCGB1A1 SFTPB MUC4	0.158359	UP
CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP	TNC LEPR CD200 SPRY1 TGFB3 ENG PDGFB PIM1 TGFB2 ANGPT2 UNC5B THBS1 HOXB5 ADM EDN1 F11R CXADR	0.158965	UP
LE_NEURONAL_DIFFERENTIATION_DN	CDC25C SEMA5A CDC20 CCNB2 CKS2 EIF4EBP2 KIF23 MRPL11 UBE2C E2F2 SUV39H1 RGS12 PKMYT1 MSI1 CDK4 CCNT1 LHX6	0.15921	DOWN
WORSCHECH_TUMOR_REJECTION_UP	CCL11 CXCL2 IFI16 ALCAM LCK ITK CCL22 CCR10 IL7R CCL4 CXCL1 TNFRSF1B TNFSF11 MX2 CLEC10A IRF4 IFIT1 IL1B TLR6 IL2RG NKRF STAT2 TLX1 FASLG TNFRSF4 TLR4 NKIRAS2 MSR1 IFITM1 IL5 CCL5 CKLF CCL1 GZMB KLRD1 STAT6 IL1RAP IL1A IFNG NFAT5 CXCL11 IL36G IRF6 IL17RB CCRL2 IL7	0.159463	UP
SANA_RESPONSE_TO_IFNG_UP	CFH SERPING1 OAS2 CX3CL1 C1S IL23A IFI44L HLA-DQB1 BST2 HLA-DQA1 PLA1A SSPN TRIM22 HLA-DPA1 HLA-DMA HLA-DRB5 APOL3 HLA-DRB1 SAMHD1 ST8SIA4 IDO1 VAMP5 MMP25 UBD SLC25A28 UBE2L6 SEPT4 APOL2 WARS MX1 APOL1 ETV7 IFI30 IL18BP HAUS7 RARRES3 RAC3 CXCL9 GBP1 ATP6V0A4 CXCL10 PPP3CA LAP3 HLA-E HLA-C HLA-B HLA-A IFI35 RABL3 CXCL11 LIPG IFIH1 LGALS3BP CASP1 TNFSF10 LGALS9 HSD17B11 DDX60 GOLM1 CEACAM1 OAS1	0.15949	UP
MMS_MOUSE_LYMPH_HIGH_4HRS_UP	NQO1 HMGB3 MARK2 VPS4B CDC6 EIF1AY LYPLA1 SPIN1 PLK4 TXNRD1 PGRMC1 CYB5A ATP6V1A PSMA3 SP3 RCN2 PELI1 XBP1 VBP1 UBA3 RRM2 ACTG1 FEN1 PTDSS1 EIF4A2 RBBP7 RBBP6 DCK PRKAR1A LMO4 CXCR4	0.160272	DOWN
REACTOME_MITOTIC_G1_G1_S_PHASES	CCNA2 CCNB1 ORC2 PPP2R1B DHFR CDK7 PSMC6 CDC6 CKS1B SKP2 CDC7 FBXO5 PSMB8 CDKN1A ORC5 PRIM2 CDKN2B ORC4 CCNE2 PSMD3 PSMA5 PSMD7 MCM4 PSMD13 PSMB10 CDT1 PSMD10 ORC1 MCM2 CDK1 TFDP1 PSMD11 PSMA3 PSMC4 PPP2CB TYMS PSMD8 HDAC1 RPA3 PSMA6 POLE2 PSMF1 CCNH PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 PCNA CCNA1 PSMC3 PSMA2 PPP2R2A PSMA7 PSMD1 PSMB7 PPP2R1A E2F2 POLA1 PSMD2 PSMB5 ORC6 PSMD14 SKP1 RRM2 PSMB6 MCM7 PSME2 PPP2CA CDKN1B PSMD12 PSMB1 DBF4 PSMD6 PSME1 E2F3 RB1 RBBP4 PSMB4 PSMB9 PSMB2 MCM10 RPA1 PSMC2 PRIM1 PPP2R3B PSMC5 RBL2 CDC45 DYRK1A PSMD4 PSMC1 ORC3 WEE1 E2F4 CDK2 PKMYT1 MCM6 RPA2 RPS27A MAX POLE MCM5 RPA4 LIN37 E2F5 CCNE1 UBA52 CDK4 MNAT1 CDKN2A MCM3 TK2 E2F1 RBL1 CUL1 CCND3 CDKN2D CDC25A MYBL2 CCND2 POLA2 CDK6 CDKN2C MYC CCND1	0.160676	DOWN
SENGUPTA_EBNA1_ANTICORRELATED	SYT11 FAM107A LIMS2 SFXN3 PLA2G16 PLK3 PITX1 TNFSF12 FCRL2 GATA2 FMNL1 KCNAB2 IDS CYFIP2 TRAF3IP3 CD247 SYDE1 MARCH2 TFEB GDPD5 C19orf66 TTLL3 PLEKHF1 SLC25A28 PRX NAT6 CTLA4 ACTN2 ARHGEF1 EPN2 KCTD17 NHLH1 LRCH4 CLEC2D KCNK7 SLC6A11 STK10 SUN2 RASA3 ZDHHC14 CRX SYMPK UBE2O CSF2 STARD3 KCNG1 NIN POU6F1 EML3 SIGLEC7 CAMTA2 TNFSF14 ZBTB17 LENEP AIM1L SP100 NEU3 H6PD RRP1 CYLD GADD45B ZNF324B CACNA1I WDTC1 ESR2 NSUN5 SREBF1 PTPN1 ITGB3 RAPGEF1 HSD17B1 MAP2K3 ZNF710 SPG7 VAV2 KRT4 PDE6B ATP6V0E1 HPX FGD2 FUT5 ARGLU1 ARHGAP4 CTNS CISH MCF2L C1orf186 PLEKHM1 ANXA9 ZBTB7A AURKAIP1 B3GALT4 HLA-A HLA-F SIDT2 GALNS PTPRE ANXA11 SMPD3 RPS6KA1 PPARD FAM45A BBIP1 MSRA KIAA0513 LIMD1 FAM105A	0.160715	UP
ROSS_AML_OF_FAB_M7_TYPE	SDPR TIMP3 DNAJC6 MYH10 DLC1 RYR3 PCDH9 RDX SERPINI1 KCNH2 GJA4 TEK PROS1 GATA2 FADS2 APOC1 DNM3 PTGS1 ICAM4 TFR2 GP1BA GATA1 TAL1 TPM1 KLF1 APOE ANK1 CTNNBL1 ITGA2B DRAP1 HLTF MYL4 ARMC8 KEL RHAG PNMT SQLE CUTA PSMD6 UROD ZMYND8 RASA1 ALDH1A1 C14orf2 DNAJC9 SOD1 PDLIM5 CD164 LAPTM4B NET1 FHL2 STXBP6 VPS37B NDUFB6 BMP2K PDCD10 ABCC4 MRPS12 HIGD1A NEO1 PLOD2 TNIK MINPP1 PCCB SLC39A4 CMAS	0.160775	UP
PID_AVB3_OPN_PATHWAY	FOS SPP1 MMP9 JUN MAP3K14 CD44 MMP2 ILK GSN NFKBIA PIK3CA PLAU RELA PIK3R1 MAP3K1 PTK2B ITGB3 MAPK8 PIP5K1A RHOA ITGAV NFKB1 SYK RAC1 CDC42 MAPK3 ROCK2 CHUK MAPK1 VAV3	0.160906	UP
REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS	TNFSF10 FADD RIPK1 FAS CASP8 TNF CASP10 TNFRSF10B CFLAR TNFRSF1A TRAF2 FASLG TRADD	0.161427	DOWN
REACTOME_CALNEXIN_CALRETICULIN_CYCLE	EDEM3 UGGT1 EDEM2 PDIA3 GANAB MAN1B1 CANX CALR EDEM1 UGGT2 PRKCSH	0.161651	DOWN
REACTOME_SIGNALING_BY_NODAL	TDGF1 PCSK6 ACVR1B ACVR2A LEFTY1 SMAD4 SMAD2 SMAD3 FOXO3 GDF1 CER1 NODAL FURIN ACVR2B DRAP1 FOXH1 LEFTY2	0.162009	DOWN
REACTOME_TRANSCRIPTION	HIST1H2BC HIST1H4H HIST1H3H HIST1H3D HIST1H2AE HIST1H2BH HIST1H2AC NCBP1 HIST1H2BD HIST1H2BG TFB2M CDK7 HIST1H2BE TAF5 HIST1H2BI CLP1 HIST1H2BF UPF3B CSTF2 SNAPC3 NUDT21 RRN3 HIST1H3E CSTF1 GTF2H2 HIST1H2AJ HIST1H2BM HIST1H4K GTF2H1 MBD2 HIST1H4B HIST1H3A MAPK3 HIST1H3F TAF11 TCEB2 CCNT2 HIST1H2BK PAPOLA HIST1H4J GTF2B HIST1H4D GTF3C3 POLR2E CDC40 BRF2 POLR2H HIST1H2AD GTF2E2 CDK9 GTF3C2 HIST2H2AA3 ERCC6 GTF2A2 HIST1H4F POLR3B TFAM U2AF2 CCNH SNRPD3 GTF3C5 POLR3E HIST1H3B POLRMT CTDP1 NCBP2 TAF4 TAF9 SRSF1 TBP H3F3A POLR1C POLR2J H2AFX SRSF2 POLR2C TAF10 HIST1H4C POLR2D SRSF9 TAF1A CSTF3 RBM8A HIST1H2BO HIST1H4L POLR2F SUPT4H1 POLR1D HIST2H4A SNRPF HIST1H4A GTF2E1 HIST2H2BE POLR2L GTF2F2 NFX1 HIST1H3G GTF2H4 SLBP SNRPB HIST1H2BB POLR2K POLR2B SNRPG GTF3C4 HIST1H2BJ H2AFZ TCEB1 SRSF7 SNRPE KAT2B TAF13 POLR2A TCEB3 HIST1H4E U2AF1 SSRP1 POLR3K TAF12 DHX38 POLR2G HIST1H4I CPSF1 TAF6 SRSF11 ERCC3 HIST1H2AB MAGOH CBX3 SRRM1 RNPS1 SRSF4 NFIB HIST1H3I GTF2F1 LZTS1 HIST1H3C PABPN1 SRSF6 POLR2I PCF11 GTF2A1 H3F3B ZNF143 RNGTT SNAPC4 MNAT1 SNAPC5 GTF2H3 TCEA1 POLR3C SUPT5H ELL POLR3F POLR3D SRSF3 RNMT SSB TAF1B CCNT1 HIST1H2BN UBTF SRSF5 HIST1H2BL HIST1H3J BRF1 ZNF473 CPSF7 POU2F1 SUPT16H EHMT2 TAF1 TAF4B SNAPC2 SNAPC1 TAF1C ERCC2 POLR1B PTRF	0.16231	DOWN
UDAYAKUMAR_MED1_TARGETS_UP	AMMECR1 EXPH5 PTER CEP70 SDC1 SLC16A1 SLC35A2 SCRN3 RBM47 AURKA FDX1 CBS EML4 ASPH APEH TSPAN12 PTPRF CTNND1 HIGD1A DHFR MRPL42 RMND5A CHPT1 GCH1 PHB AIMP2 ME2 CDC6 CNOT6 ME1 PKN2 FECH NIT2 TMED7 MRPL12 TMPO NF1 THOP1 GRSF1 SLC19A1 KIAA0101 KATNB1 PAWR AKR1A1 SLC16A3 STX6 PFKL SREK1IP1 FAM173A ACSL3 LARP4 C21orf33 DHX15 SLK CCNJ KIAA0368 TSFM DUS1L FEM1B EDF1 RYK NSMAF PANK4 RDH11 CREB1 MTDH EIF3A LBR PSPH MYO19 EIF2AK2 DCP2 NUBP2 DTYMK PJA2 SUB1 LIG3 ANAPC5 LONP1 CD47 PTMA RC3H2 IPO7 RPL22 TCF25 PHF10 UBR5 SSX2IP PSAT1 DICER1 SDF2L1 NAGLU ASNS DDHD2 METRN CHAF1A GARS LRRC14 MBNL1 BOP1 DARS EIF4EBP1 FKBP14 BPGM MED1 MALT1 ECEL1 OGG1 SF3A2 BRD9 ZMYND11 TLE6 PPP3CB KLHL23 LRP8 TROVE2 POLR3G ANP32E KDELC1 ZNF580 OSBPL8 SRGN PITX1 SLC29A1 MAD1L1 TSPAN4 RHOQ SEPT6 CAMSAP2 AP1S2 CAV2	0.162418	DOWN
ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP	SCYL2 ABCB11 GNA13 PERP PRKAB2 HIST1H1C CYP51A1 SORT1 F11R PCTP MYO1B IFT74 CDHR2 TSPAN8 SLC17A4 SH3YL1 NAT8B UGT2B28 MET GPX2 SLPI CHKA PON2 WSB2 CISD1 SEPT11 FAM162A UAP1 IMPA1 YAP1 CYP3A5 MARCKS DCTN4 LMAN2 CHD1 HES1 LIPG SACM1L EDEM2 CTSO BLVRB METTL7A TBPL1 ALG5 GORASP1 PHF3 GAK NTAN1 CYP3A7 UBE2V2 RBM34 TRIT1 DPP4 UQCRH PTGES3 APOM ARPC5 HLA-B GADD45G FAM188A ERGIC2 PNN ITGAV RPN2 ZNF212 OS9 FGL1 LAP3 IGBP1 FRG1 EIF3A AHCTF1 TRIP12 HDAC2 SESN1 ACTR3 FAM98A ARMC1 RNH1 RIC8B ANGEL2 HNRNPH3 PTMA RPS3A YRDC ATG16L1 AFM HNRNPA2B1 RPL7 RPLP1 RPL7A RPL27A SAR1A MBL2 HMGN4 RBM5 PNMA3 M6PR DYNLRB1 USP49 SUMO2 PEX3 PNISR DDX27 IGSF6 TDRD1 SLC15A1 PLEKHA5 RPL14 C9 CUX2 GSTA4 RPL23 NUCKS1 FBXO2 HCFC1 RBM6 ZNF14 RAB33B ZNF266 NISCH COL3A1 ZNF721 FKBP5 CFHR2 MYCBP2 ZFP36L1 ACSM5 A2M PLA1A ALCAM HHEX GMFG ACSL4 ZDHHC11 LY96 ELOVL5 RGS2	0.162498	DOWN
LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_UP	TFCP2L1 GCLM IRF6 CLCN3 ACADM LXN SLC35D1 LYRM2 ITFG1 EIF4E FHL2 PAWR GAS2 GFI1B APLP2 UBE2D3 QDPR MAT2B TMEM5 CCNB1IP1 MYBBP1A STX7 FCER1A C15orf39 SCAMP1 COMT GSTA4 EIF3B S100A11 AGRN TPM4 CCR5 GTF3A FADS1 PLS3	0.162524	DOWN
KEGG_LYSINE_DEGRADATION	EHHADH HADH PLOD2 ALDH7A1 ACAT1 HADHA ECHS1 ALDH3A2 ALDH2 DLST ACAT2 GCDH TMLHE WHSC1 ALDH9A1 SUV39H2 AASDHPPT WHSC1L1 DOT1L SETDB1 ALDH1B1 OGDH PLOD3 SETD2 ASH1L SETD1B SUV39H1 AASS SETMAR NSD1 EHMT2 PLOD1 EHMT1 BBOX1 SETD1A OGDHL PIPOX	0.162637	DOWN
CREIGHTON_AKT1_SIGNALING_VIA_MTOR_DN	TSPAN1 KRT8 GOT1 CTSA CIB1 GPI ALDOA DHCR7 MRPS7 PFKL PPP4C ATP6AP1 TOM1 YWHAB ATP6V0B PPP2R1A ATP6V0C PAFAH1B3 MIF TUBB4B ATP6V1F TNFRSF12A RGL2	0.162692	DOWN
SU_TESTIS	HMMR TTK NEK2 NXT2 AURKA CCNB1 OIP5 CCNB2 ITCH STAM2 IDE EZH2 BUB1B CDKN3 KIF2C PSMG1 TOPBP1 PPFIA1 COIL CDK1 NCAPH ACRV1 PRKAR2A TTLL5 SFMBT1 NUP155 BUB1 RAD17 HSF2BP PHKG2 CCT6B TMF1 BRAF PMS1 DBF4 MPP6 ART3 BRDT GK2 IRGC SYCP1 NF2 MTOR ZPBP ABCB6 CYLC2 ADAM2 MLLT10 SSX3 SYCP2 BRD1 ZNF165 DAZL GRK4 TEKT2 CLTCL1 RBMXL2 TLE4 TULP2 SMCP ZNRF4 CLUAP1 SOCS7 ZMYND10 CAMP SOX5 RPL39L MLF1 RFC4 PRAME GPR135 PIWIL1	0.16273	DOWN
BROWNE_HCMV_INFECTION_6HR_DN	GAS1 NAP1L3 OSR2 STON1 THBD TSPYL5 MN1 FRY MEIS1 SCHIP1 DUSP10 FBXL2 AMOTL2 BHLHE40 S1PR1 TCF21 ITGAM C10orf10 FGF2 ARL4C TSPYL4 PRKAR2B ARID5B ARNT2 MDM1 RGS19 CREB5 ETV1 CEP68 NR3C1 CEP112 ADCY7 DUSP6 SRGAP2 FAM168A NTF3 S100A3 ALMS1 PHF20 TTF1 P2RY10 PRR3 CLCN6 MDC1 TTC9 TROVE2 GLI2 SGK1 MNT TSC22D2 HDAC9 BICD1 KANK1 TBC1D8 ARHGEF2 RIN1 ZNF8 TLE4 ZBTB24 MSX2 TXNIP DFFA FBXL5 BCL9 BRD1 PIK3R1 MTAP HOXC6 DMTF1 PNISR SCAF8 WEE1 YLPM1 ELF2 HOXA11 DOPEY1 ITGB3 CDS2 YTHDC1 MDM2 OFD1 DKK1 ZNF24 GRIK3 CSTF2T ID2 ITGAE EPB41 BDKRB2 CDKN1B STAU2 ZNF175 CFLAR PRDM2 RND3 MTF2 RNF113A PCMTD2 GOSR2 SMAD3 BACH1 CBLB ZNF230 SMAD5 TDRD3 ZNF623 LRIG2 ATPAF2 CDC40 ANKRD28 PHF3 GAS2 ZNF44 GRM8 COIL TCF7L2 TGIF1 MED21 KDM6A CDC23 RPE SMAD1 ICA1 RPP14 CDKN3 GLOD4 CENPF KIN HOXA10 FADD NCK1 GLB1L2 THOC2 PARP4 ITGA6 PPP2R1B PEX11B LAMC2 AGGF1 TRIM2 ORC2 PLCB4 DSP TJP2 CASP6 PEX7 F2RL1 HMGA2 FPGT PSG3 MTM1 IL7 SLC22A4 ACOX1 ADORA2B	0.16289	UP
MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS	GUCY1A3 CXCL12 MAL VPREB3 DPYSL2 GYPC NUAK1 MAFB CX3CR1 CCND1 CYBB MAF NTRK2 CCND2 ITGB7 PXDN TBC1D9 FAM174B CD99 TLR4 KCNMB2 GNAQ ABLIM1 SRC ATP13A2 WHSC1 GALNT10 PYGB KLF4 FGFR3 SORT1 IL6R PKP2	0.162976	UP
WANG_CLIM2_TARGETS_DN	ETNK1 OCLN RNFT1 GNA13 MPZL2 SPAG1 GALNT7 NAA35 HMGCS1 TRIM2 BLZF1 RP2 SEC23B CHMP5 RNF14 KCTD5 SAMD9 MTMR2 CD24 PEX1 SEC23A WSB2 IMPACT RCHY1 DNAJC15 MSMO1 TAX1BP3 LGALS3 ARHGAP12 IDI1 STXBP3 FAS GCA RAD23B PRIM2 ZNF91 CAPZA2 CRK MRPS11 CYP20A1 COIL LRP10 PGM3 SLC25A44 IFRD1 RARS F12 TMEM11 NCOR1 SREK1IP1 GPR87 RRP15 TOMM22 ACBD3 ATG12 COPS5 PPP4R2 MYNN DPM1 MYL12B FAM149B1 TIPRL B4GALT1 PFDN4 GULP1 PDPR JRKL AP1S1 ARPC2 BSDC1 UTP18 CLTA DUS1L SERINC3 UBA3 WDR45 CASP9 SF3A1 TOPORS PPP1R13L COBLL1 RDH11 UBE2L3 MRPL9 ITM2B JAG1 HBS1L API5 CCT6A STAT1 SPTBN1 SYPL1 HNRNPK FARSA PAM16 ATP6V0E1 GTPBP4 STRN3 GADD45GIP1 IRF9 NEK7 YRDC TCEB3 CTSB ASF1A RPP30 CEBPZ PRPF40A MEX3C SCML2 PPP1R9A MED13L PFDN1 SRRM1 SP100 SUMO4 ZNF281 CCDC86 RBBP6 MBNL1 DAXX PHF11 TNKS2 LRRFIP1 ELL REST TUBGCP5 DIP2A ISG15 AKIRIN2 DUSP3 ZNF292 TBC1D9 IFIT1 GABRR2 PCDHB3 TNFRSF12A ST3GAL1 CLIP1 IFI6 PBX2 RRAS STOM KPNA5 GATA2 PAM CPE KLF7 TSC22D3 TFPI	0.163124	DOWN
REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX	DLAT PDK3 PDHX DLD PDHA1 PDK2 PDK1 PDPR PDHB PDK4 PDP1	0.16354	DOWN
REACTOME_GLUCONEOGENESIS	SLC25A13 PCK1 PCK2 SLC25A1 FBP1 GOT1 ALDOB MDH2 PC SLC25A11 SLC25A10 PRKACB GPI ALDOA PGK1 MDH1 TPI1 ENO1 GOT2 GAPDH PGAM1 PFKFB1 SLC25A12 FBP2 GAPDHS PGAM2 PRKACA ALDOC PRKACG ENO3 ENO2	0.163724	DOWN
LEIN_OLIGODENDROCYTE_MARKERS	CRYAB APOD SYT11 TPPP3 DAAM2 QKI PTGDS MCAM PLEKHB1 CD81 ACTC1 CSRP1 ARHGEF10 CLIC4 GATM TSPAN2 GPR37 CNTN2 GSN MOBP SLC48A1 SGK1 SEPT4 CCP110 SOX10 MAG AATK PACS2 TMEM63A MTRR OLIG2 ABCA2 CNP PLEKHG3 S1PR5 EEF2 OMG CERS2 RNF13 MOG HCN2 NPC1 MBP SLC44A1 FRMD4B QDPR PCYT2 TMBIM6 TALDO1 FABP5 NDRG1 SCD SERPINB1 HMGCS1 SERINC5 WSCD1 MAP2K6 GJB1 CA2 GLTP FA2H UGT8	0.164021	UP
KEGG_SPHINGOLIPID_METABOLISM	UGT8 GALC SGPP1 NEU1 GLB1 SGPL1 SPTLC1 GBA SMPD1 SMPD3 SPTLC2 SPHK2 SMPD2 GLA GAL3ST1 ASAH1 CERK KDSR UGCG ARSA NEU3 NEU2 B4GALT6 SMPD4 SPHK1 SGMS1 DEGS1	0.164552	DOWN
STEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN	PTRF LPL SPP1 CCL3 BASP1 LAPTM5 CSF2RB CTSK APOC1 RASGRP2 SOCS3 NOV POU3F2 ITGAX PLD3 MYO7A ACP5 TBL3 SNCB SND1 AES AGPAT1 CD68 SP4 GJA5 RAP2B CLEC4A F7 ADAM15 CTSZ IQGAP1 PSMA4 CFL1 ATG7 SYK BCL2L11 LRP5 COX6B1 SEMA6A SAT1 PIGT PDIA4 LCN2 CTSD LY75 CSTB CTSS	0.165359	UP
CHEN_HOXA5_TARGETS_9HR_DN	MYL9 LOXL1 LPCAT1 FZD2 EHD2 PCDHGC3 SLC29A1 SV2A WNT5B CBX6 FAM127A SERPINH1 FJX1 GM2A UBTF GEMIN4 PRR16 INO80B MAT2A GLG1 FEN1 SYNGR2 G6PC3 H2AFX AP1S1 ANP32A CKAP4 TOMM22 ST6GALNAC4 AKAP1 MARCKS SKP2 TMEM97 KDELR1 DDT HMGB3 ANPEP	0.165646	UP
VALK_AML_WITH_11Q23_REARRANGED	CES1 ITGA7 CADM1 PENK C1orf54 RET UVRAG MSLN CACNA2D3 CD70 APOC2 TKTL1 C3orf14 HIF1A TGM5 P2RY2 TRPM4 DACH1 NXT2	0.16589	UP
SHI_SPARC_TARGETS_DN	SPARCL1 SPARC ITGB2 KIT BBC3 MAP3K8 SEMA3B AHR TP53TG3 PPP5C RAB40B	0.165921	UP
CADWELL_ATG16L1_TARGETS_DN	NETO2 HSPA1B SATB2 PPARGC1A OIP5 SPATA5L1 CLDN8 CCDC88C IVD FANCF BUB1B YTHDC2 DHRS1 ADI1 NFE2L2 TUBGCP4 GDAP2 PPIP5K1 SLC15A2 CAP1 TCHH HSPA1A P4HA1 USP53 RALGPS2 SKIV2L2 TTR RNF187 TTC3 DNAJA4 PDK4 HAL TP53 VPS39 GIP THOC1 H3F3B MCC HSPA4L PPFIBP1 NUP62 SGK1 ZNF266 HAUS2 SULT1C2 PER1 IGFBP7 RGS5 VCAM1 SFRP1	0.166029	DOWN
JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_DN	RGS1 CSRP2 PTPRM ARHGEF6 PDGFRB RGS16 CD83 SFRP4 CSNK1E RGL2 PMEPA1 TAL1 FOXO1 KDR NCOA1 PON1 MAST1 WNT2 CD36 SUGP2 MMP13 GABRP RCL1 SRSF11 ZNF211 POLR2A APEX1 ITGAE RYBP SYT17 BMP6 BRE PTEN GOLGA1 SBNO1 YTHDC2 PLXNA2 IL7 PDE6A	0.166498	UP
LAIHO_COLORECTAL_CANCER_SERRATED_UP	CTGF CAV1 PMP22 CSRP2 RASSF2 EMP3 ELK3 PRNP DPYSL2 LGALS1 LAMC1 SPARC PAM C1S ANXA5 PALLD TCF4 MACF1 HLA-DRB1 LCP2 SVIL DPYD PDGFC ANP32E IL6ST TROVE2 SNRK PXDN TM4SF1 ARPP19 PRKAR1A SEC62 PLA2G4A HNRNPC MBD4 GBP1 SUMO2 PSMD4 HIF1A LAMB1 MORF4L2 SPG21 CTSB SRP14 COMMD3 SNRPE BNIP3L NEDD8 ATP6V0E1 MYL6 ARL8B C5orf15 SGCB SDCBP CSNK1A1 AP2M1 VDAC3 NPTN LSM3 RBX1 B2M RPL36AL EPRS TAGLN2 SERF2 NOP10 GDI2 CAPZA1 HSPA8 YME1L1 ARPC2 IQGAP1 MYL12B PELI1 NDUFV2 MRPS14 NCOA4 RBM34 PDIA6 CLINT1 MFAP1 PDLIM5 VAPA OPTN ADAM10 ANXA2 DAD1 ATP5C1 SEC24A BCAP29 RIN2 PPIC MON2 ATP1B1 CEACAM6 ORMDL2 PLEKHB2 CHMP2B ATP2B1 IFI27 GCNT3 POSTN DDX60 CNIH4 PLS1 EMP1	0.166743	UP
MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	SYNM NEFL PTGER3 INA CXCR4 CXCL12 NEFM PCSK2 KIF5C KCNMA1 PLTP TGFB1 RELN CPEB1 NMNAT2 FOXF1 FOXF2 GNAL ADAMTS8 COCH NGFR HOXD13 HS3ST3A1 MAPK8IP2 RET PLAG1 CDH11 SLC26A4 NXPH3 KCNA1 AK5 GALNT14 ST8SIA2 CHST8 ADAMTS2 A4GALT AFF3 LAMA1 FOXD4 NPPC SATB1 WNT11 BMI1 PCDH8 TACR1 ACAN CDK5R2 HMX1 AHNAK CRH HOXC4 SFI1 SLC6A15 ASCL2 GPC5 FOXC2 NEUROG1 RGS6 MSX2 ADRB3 SNTB1 PTPRU FLT1 ADORA1 CELSR3 SHH PTPRN2 ADRA2B MYRIP CHRNA5 SEMA7A SIX2 KLHDC8A CDH22 FOXB1 KCNK12 CBLN1 HOXC5 GPR88 FGF5 BMP8A TFAP2A EGR4 GDNF VGF RASGRF1 KCNJ4 CCNO KCNC4 PLEKHG3 HRK GJA3 AP3B2 KCNA3 NEUROG2 NTNG1 PTGER4 SMAD6 MNX1 PRMT8 CASZ1 TEAD4 SPATA2L PSMB9 ESRRB GPR45 CDHR1 NXPH4 SOX1 TUBA4A GAD1 TUB ITGA3 SLC24A2 GABRA4 KDELR3 IGF2BP2 BIK MMP24 ARG2 WNT6 CDKN1A FGF9 RAB20 GPRC5C MAP3K9 GCH1 P4HA2 ATOH1 NDRG1 GCHFR KCNK1 SLC35F2 CDS1 STX3 ATP7B ERBB3 GATA6 HOXD1 SLC30A10 OCLN ADORA2B	0.168717	UP
BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_UP	TIMP3 PMP22 CDO1 DCN AQP1 PRRX2 NR1D2 DDIT3 PDGFRA GADD45A TMEM176A ALDH1A1 TMEM176B DHRS7 GBE1 HSD17B11 LXN	0.168786	UP
DORN_ADENOVIRUS_INFECTION_48HR_DN	CYR61 EGR3 NR4A1 JUNB CD83 IER3 IL6 EPHA2 CCND1 COL7A1 TNFRSF12A SGK1 NFKBIA PLK2 MFAP2 SNAI2 CCNK SRSF5 ELL2 MCL1 CYTH1 FUBP1 MAP2K3 HNRNPH1 SYNCRIP SDCBP KRT14 EWSR1 RND3 SRSF1 TRAF4 FHL2 RAB1A NFE2L2 TXNRD1 EFNA1 BCAR3 KRT19 SERPINB5 KLRC2	0.168844	UP
PUJANA_XPRSS_INT_NETWORK	MAD2L1 HMMR CENPA TTF2 CCNA2 AURKA GINS1 TOP2A ZWINT CDC20 RAD51AP1 TFDP2 MKI67 FOXM1 DHFR RBBP8 NCK1 SPC25 EZH2 NDC80 MPHOSPH9 SKP2 CDC7 SMC2 CSNK2A1 UNG RIF1 PLK4 LMNB1 PAICS TMPO ACYP1 IDH3B NCAPD2 ESPL1 KIAA0101 TOPBP1 METAP1 MCM4 ATP11B MCM2 CDK1 TFDP1 SRSF10 SMC4 BRCA1 TAF11 CHEK2 ZNHIT3 WHSC1 BRCA2 RPIA SNRPA1 UBE2C ABCB7 MRE11A DDX46 DNAJC9 LARP7 AURKB PPP1CC ZNF330 RFC3 PCNA PRKDC MSH2 SMC1A PNN RRM1 TOP1 SMC3 DEK HMGN1 RAD21 TIMELESS MTF2 SLC7A1 PAXIP1 NAE1 FANCI POLA1 FRG1 LBR BUB3 KATNA1 DCP2 CASP2 H2AFV COPS3 RB1 HMGB2 RBBP4 SNRPB POLR2B DNA2 PRPF4 NFATC2IP CTCF USP1 TCERG1 CD47 KNTC1 EXOSC8 RPA1 ASF1A FUBP1 SEC31A PPP2R5C MAT2A KIF20B DDX39B SRSF11 TBCA HMGN4 ZNF43 RAD54L EIF3H SUZ12 MCM6 CBX3 UBE2S USP49 CEP57 POLE XPO1 MCM5 CNOT3 DUT SNRPA CPSF4 CAD CHAF1A RNASEH2B DDX39A BLM AATF STMN1 NASP CCNF KIFC1 DNMT1 TCF3 SRSF3 ZNF131 ILF3 GTSE1 RECQL MYBL2 BLMH RFC4 NFYB STAT5A CNTRL RAD51C ANP32E ATM CDKN2C SH2D1A SSBP2 PRPS1 PSIP1 KIAA0922 CD1C RHOH	0.169067	DOWN
REACTOME_ENOS_ACTIVATION_AND_REGULATION	WASL GCHFR PRKG2 DHFR SPR GCH1 LYPLA1 DNM2 PTS NOSIP CALM2 CALM3 CALM1 HSP90AA1 AKT1 NOS3 CAV1	0.169072	DOWN
REACTOME_METABOLISM_OF_NUCLEOTIDES	XDH GSR UPP1 CDA TXN UCK2 AK2 PNP ADSS CAT NT5C2 PAICS TXNRD1 CMPK1 CTPS2 AMPD1 NT5E UMPS HPRT1 ADK GLRX TYMS TK1 DGUOK GMPR2 ATIC GUK1 GART RRM1 AK1 APRT DPYS RRM2 NME2 DTYMK NME1 DCTD IMPDH2 DHODH ADSL AMPD3 PFAS GPX1 DUT CAD DCK TK2 TYMP GMPS GMPR PPAT UPB1 AMPD2 NT5M IMPDH1 AK5 DPYD ADA NME4	0.169209	DOWN
REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_	FN1 VWF TLN1 FGB APBB1IP ITGA2B FGA ITGB3 RAP1A PTK2 GRB2 RAP1B FGG SRC SOS1	0.169917	UP
DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP	CXCR4 ATP2B4 SAMSN1 S100A8 IGFBP7 CTSG LAPTM5 LCP1 FNBP1 CD302 RASGRP2 HSPA6 LST1 C11orf21 PSTPIP1 SLA MYO1F NKG7 MS4A3 CSF3R SELPLG NUCB2 NFE2 PRG2 SPCS3 CST7 RNASE3 BTG1 BPI LYZ ALDH3B1 ALOX5AP ICAM3 PTGER4 PRRC2C RNASE2 OS9 FAM192A AZU1 ACOT7 ITM2C GCA CAT CD24 CEACAM6 PLAC8 ARL15 IL6R	0.17006	UP
NADERI_BREAST_CANCER_PROGNOSIS_UP	ASPM FA2H CEP55 MELK KIF20A EBP TRIM24 FADD NDC80 HSPA14 CENPN ATP2C2 RACGAP1 TMEM208 CDCA8 TNNC2 SPAG5 PTTG1 BUB1 TIMELESS PSMD2 PSMD14 PMCH SMARCA4 SHMT2 RNFT2 DSCC1 EXO1 MLLT1 AQP5 POLD1 PDX1 MYBL2 PRAME CARTPT AMH SOX11 SEMA4C BAALC RASIP1	0.17039	DOWN
FOURNIER_ACINAR_DEVELOPMENT_LATE_DN	ASPM FGFBP1 CEP55 AURKA ZWILCH FOXM1 CKS2 CDKN3 NCAPG RRM2 VRK1 EIF4A1 TUBG1 ACTB TRIP13 CAPRIN2 ODC1 DUSP4 EPHA2 SERPINE2 ACTN1	0.170491	DOWN
GHANDHI_DIRECT_IRRADIATION_DN	MN1 OLFML2B S1PR1 C10orf10 FZD4 PER1 PBX2 TOX BCL11A PTK7 FAM50B NFE2 MDFI ELANE OPRL1 HOXB3 S100P SYBU G6PD CCDC85C IRF1 MRPS6 PLEKHA6 NR3C2	0.170491	UP
QI_PLASMACYTOMA_DN	PTGIS LYVE1 CCL11 AEBP1 FSTL1 COL5A2 SPARCL1 COL1A1 BASP1 COL6A2 MAGEH1 DYNC2H1 COL4A2 TIMP1 EXTL2 CYTIP INHBB CSNK1E CALU SVIL TRIB1 CLIP1 MYC MMP2 EEF1A2 LBP IGFBP3 NOL3 LZTR1 KRT32 DUSP22 SKIL RNF25 MFAP2 ETV4 TRIP6 MATK KAT2A ALPL STAT2 PARK7 SND1 CTSW IPO4 LYPD3 CHST1 LAMB1 PVR EIF4A1 SEC63 NOL8 MYBBP1A MAGED1 EPAS1 RGSL1 BMP1 PDGFRA ARFIP2 SEC61A1 PIGK ICK ITGB5 PRMT7 VEGFA GANAB PSMB3 P4HB SENP2 XBP1 SRP9 TBRG4 DDOST PPP2R5A BLNK C1QBP RABGGTA UCHL5 FARP2 MYH14 SPON1 P4HA2 SLPI STT3A ST14 LAMC2 GNE EPCAM ARHGAP8 ENPEP BSG AGR2 WASL	0.170677	UP
SHIN_B_CELL_LYMPHOMA_CLUSTER_7	NOTCH3 CDKN1C BCL6 ZFP36 NOTCH4 DVL3 IL6ST GLI2 PML WNT4 XRCC3 RARG MAX DICER1 TERT DVL1 PTCH1 STAT6 RB1 DKK4 IGF1R PTEN BAD TRAF4 TEP1 GSK3B APC	0.170721	UP
KEGG_GLYCEROPHOSPHOLIPID_METABOLISM	ETNK1 GPD2 PLD1 PLA2G10 CDS1 LPCAT3 LPCAT4 AGPAT2 GPD1L CHKA PLA2G12A CHPT1 LYPLA1 MBOAT7 AGPAT3 PCYT2 DGKH MBOAT2 LPGAT1 PCYT1A GNPAT PLA2G2A DGKD PGS1 PLA2G2F LYPLA2 DGKQ CDIPT PISD PLA2G1B PLA2G15 PTDSS1 PTDSS2 CDS2 CHKB PLA2G3 PLA2G6 DGKA AGPAT1 CHAT DGKZ DGKI PEMT PLA2G2E TAZ PLD2 DGKE PLA2G4A ETNK2 JMJD7-PLA2G4B GPD1 PCYT1B ACHE DGKG AGPAT4 PLA2G2D DGKB LCAT PLA2G5 LPCAT1	0.170733	DOWN
KIM_MYCL1_AMPLIFICATION_TARGETS_DN	GSTM4 NRAS GRHL2 VANGL1 KIF3B MT1X OAT RUNX1 FKBP9 PHTF1 CDC42EP1 CMTM6 AHNAK C1orf61	0.17078	DOWN
FIGUEROA_AML_METHYLATION_CLUSTER_6_DN	AHNAK2 CSGALNACT1 AIM2 CD3D PLEK DEFA1 PLD3 ZNF862 FKRP IL2RG GRTP1 GPR17 KRTAP5-9 ASXL3 CCL1 STRN4 CD3G GBX2 PSMD2 CTDP1 POU4F2 TACR3 DNAJC28 TCP11 GPR39	0.170784	UP
KIM_MYCL1_AMPLIFICATION_TARGETS_UP	NEFL NDRG4 CD19 NELL2 KCND2 CDK5R1 GPR27 FAM13C HPCAL4 RHOBTB3 PRSS12	0.171102	UP
HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP	THBS2 CD69 TMEM158 ELMO1 LAMA4 TYRP1 HHEX LCP1 ITM2A LUM GATA3 CD3D PRKD3 LAMA1 MAF PHLDA1 KLRK1 DMWD PLAU ETV4 KLF9 C11orf68 CSF1 DCT TYR ABCA1 ASNS CD68 IL1RL1 TPR FOLR1 MARCKSL1 ARPC1B CD47 S100A2 PLK1 APOH SGCB SLC1A5 SQSTM1 HIST1H4C PRSS23 GADD45A MT2A PLAT HMGA1 IL32 MT1X HIST1H4B NT5E MBOAT7 SOD2 RGP1 CKS2 TFF1 HIST1H2AC MAP7	0.17113	UP
BIOCARTA_IL2RB_PATHWAY	FOS IRS1 STAT5B SOCS3 MYC PIK3CG PTPN6 BCL2 IL2RA STAT5A PIK3CA IL2RB IL2RG SOCS1 E2F1 AKT1 JAK1 PIK3R1 FASLG JAK3 HRAS CBL SHC1 RAF1 GRB2 CFLAR IKZF3 PPIA BCL2L1 SYK RPS6KB1 BAD MAPK3 CRKL SOS1 NMI FAS MAPK1	0.171205	UP
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_2	FOS THBS2 TNXB TACR2 ELN RELN NPTX1 ARL4D PIK3CD GNAO1 MMP2 DPEP3 BCL2 KLRG1 SOX5 CLGN CDH3 CAPN3 MED22 CYP1A2 AASS MYLPF HOXC6 CDON KPNB1 NMU OGT AKAP8 SRRM2 RHO PKLR ATAD3A SLC4A1 CCNL2 RBM39 ACTB ESR1 BCL2L10 MMP12 RPP30 FUBP1 UBAP2L SNX17 RPL22 TIPARP SRSF7 NME1 NR0B1 CLK1 SOX3 PLA2R1 CLK4 HNF1A SFPQ OSBPL9 TARDBP BAD SNX5 BIRC2 KCNQ1 RAB14 BMP2 GCNT2 CLPX HGD ENPEP AKAP9 EPB41L4B	0.171298	UP
OXFORD_RALA_OR_RALB_TARGETS_UP	DTL ZWINT SLC20A1 HN1 PGD TMEM97 CDC6 PPIF CCNE2 PSMD3 MCM4 ERI3 NET1 SAC3D1 MCM2 CDK1 TYMS WHSC1 BIRC5 METTL13 UBE2C DNAJC9 HMGA1 AURKB CENPM H2AFX EXOSC4 RRM2 MCM7 DKC1 FARSA E2F3 FEN1 ASNS EXOSC2 MCM5 NONO STMN1 CCNE1 BOP1 PLXNA1 LAS1L CDC25A GNA15 TACC3 CCND1 NINL	0.171535	DOWN
PID_LYSOPHOSPHOLIPID_PATHWAY	FOS HBEGF PRKD1 MMP9 JUN TIAM1 MAPT ADCY2 GNAI2 GNAZ IL6 ADCY7 GNAO1 MMP2 LPAR1 ADRA1B GNA12 PLCG1 GNA15 NFKBIA LYN ARHGEF1 ADCY3 GNA14 TRIP6 RELA ADCY8 PLD2 AKT1 SLC9A3R2 PIK3R1 PTK2B PRKCE GNB1 HRAS ADCY1 PTK2 PLCB3 LPAR4 LPAR2 RHOA PXN GNAQ SRC NFKB1 LPAR3 GNAI3 RAC1 GAB1 EGFR CRK ADCY9 GSK3B PRKCD GNA11 PIK3CB ADCY6 CASP3 GNAI1 GNA13	0.17202	UP
HOSHIDA_LIVER_CANCER_SUBCLASS_S2	NR5A2 PPARG HMGCR ERBB3 GNAI1 ENPP1 MEST CXADR ABCD3 CPD MAPK6 KLF3 RAB4A AHCY ATP2B1 CHKA PHKA2 UBE2K CD46 FGFR4 FLNB IDI1 CSNK2A1 ATP5F1 ACP1 FGFR3 NR2C1 IGF2R NT5E TBCE PRDX3 NET1 SREBF2 GLUD1 ADD3 PHF3 NCOA4 GTF3C2 CUL4A H1F0 EP300 SUMO1 TIAL1 NUP153 TM9SF4 PNN ARHGAP35 PLXNB1 SEPHS1 DEK TFIP11 GBF1 PPP2R1A LBR PIGC BCLAF1 ATF2 DDX1 POFUT1 TARBP1 CTNNB1 SNRPE TP53BP2 TTC3 HNRNPA2B1 AFP FBL TIA1 RPS19 HNRNPU RPS24 RBM39 RPL31 TPR RPS27 TRIM26 EIF4A2 ITIH2 ARID3A SUZ12 RPL24 RPL27 SMARCC1 RPS5 HELZ CSE1L CASC3 ATXN10 HNRNPC CLK2 COL2A1 DDX18 SNTB1 RPS25 SLC6A5 BRD3 SSB GTF2I EIF4B CSNK2A2 RRP1B SLC6A2 PTOV1 BTG3 GPC3 CDK6 ATP2B2 ATM BCAM SMARCA1 IGF2 PEG3	0.1722	DOWN
MALONEY_RESPONSE_TO_17AAG_DN	MAD2L1 ABCD3 CA12 CLDN3 CYCS RSU1 CLTB PSMA5 YWHAE ATP5C1 PRDX3 TCEB2 LDHA MDH1 PRDX4 UBE2C GTF2A2 ARF4 TPI1 PTGES3 SYK WRN KPNA2 SMAD5 ILF2 HNRNPAB ATP5I DYNLL1 GNPAT SRSF2 CLTA PSMA7 HIST1H4C BRE CALM2 TMSB4X RPL36AL SNRPF RRM2 HNRNPM HAT1 POLR2L VDAC3 PA2G4 SNRPB SYNPO PLK1 SNRPG SUB1 SRSF7 TIMM23 SNRPE SSBP1 MARCH6 XRCC5 PTMA EIF4A1 HNRNPA2B1 RBMX ABCE1 HNRNPA1 RPL27A RPL30 PDCD5 ZNF43 RPS16 NACA RPL24 IARS RPS8 RPL35 SRSF3 SSB SEC62 SNCA GM2A LTBP1 GJA1	0.172298	DOWN
SONG_TARGETS_OF_IE86_CMV_PROTEIN	MAD2L1 KIF11 CASP3 ZWINT PNP FOXM1 DHFR TPX2 EZH2 UNG TMPO KIAA0101 TOPBP1 UMPS CDT1 MCM2 CDK1 DDX52 TMEM106C RFC2 TYMS TK1 RAB27A TFAM DNAJC9 PTTG1 RFC3 PCNA MSH2 RRM1 H2AFX POLA1 POLD3 MCM7 FLAD1 PPIH DDX23 HMGB2 FEN1 RPA1 NUP214 MCM6 MCM5 BLM PSMC3IP NASP CCNE1 DCK MCM3 E2F1 CSPG5 MYBL2 BTG3 RFC4 BARD1 RAD51C FADS3 SLC29A1	0.172535	DOWN
BIOCARTA_EIF2_PATHWAY	EIF2AK3 GSK3B PPP1CA EIF5 EIF2AK1 EIF2B5 EIF2S2 EIF2S1 EIF2AK2 EIF2S3	0.172554	DOWN
MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_UP	GREM2 CCL2 ARL4C ST3GAL4 BNC1 NOP56 ST6GAL1 RCL1 ADRM1 NME1 WDR77 CORO1C SERP1 GNL3 DDX21 SRSF2 GMPPB MRPL20 HSPA4 USP10 EBNA1BP2 TMEM97	0.172791	UP
JAZAG_TGFB1_SIGNALING_VIA_SMAD4_DN	KCNMB1 EVI2A MFNG SNX10 AIM2 RBP4 PDGFRB PNOC ST6GALNAC2 PAK3 C5 JAG2 LCP2 SPI1 ABCD1 GALR1 CLEC11A PTK7 ITGB7 CDK17 PHLDA1 FLT3LG NRG1 LTA CCL27 RASSF1 POU2F2 SLC22A6 UNC119 HRH2 GUCY2F CD1A CCNE1 TUBA1B PRODH CDRT1 RBMX2 AGPAT1 SF1 PKLR BYSL MST1 S100A1 NID2 DRD2 RPL13A PTCH1 LIF MAPK7 SH3BP2 SYNGR2 SCAMP3 NEMF HSPA4 CDK18 CYB5A VAPB CNKSR1 ITGA6 BMP2 CLDN4 VIL1	0.173649	UP
BIOCARTA_NFAT_PATHWAY	HAND1 HBEGF CAMK1 HAND2 FGF2 IGF1 PRKAR2B NFATC1 CTF1 NFATC4 PPP3CC PIK3CG MEF2C ACTA1 PRKACG PPP3CB PRKAR1B PIK3CA NPPA GATA4 PRKAR1A NKX2-5 NFATC3 AKT1 PIK3R1 CREBBP CAMK4 F2 HRAS MAPK8 LIF CALM1 CSNK1A1 RAF1 MAP2K1 CALM3 MYH2 ELSPBP1 CALM2 PPP3CA CALR CAMK1G PRKAR2A FKBP1A RPS6KB1 MAPK3 MAPK14 GSK3B PRKACB EDN1 MAPK1 AGT	0.173788	UP
REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA	PLCB1 GNG11 GNB5 GNG3 GNG7 PLCB2 GNB3 GNG4 GNB1 GNG13 PLCB3 GNB2 GNGT1 GNG5 GNG12	0.173935	UP
REACTOME_PROLACTIN_RECEPTOR_SIGNALING	STAT5B GHR STAT5A GH2 CUL1 CSH1 BTRC SH2B1 GH1 PRL JAK2 PRLR RBX1 SKP1	0.174019	UP
STAMBOLSKY_TARGETS_OF_MUTATED_TP53_UP	EGR3 THBD ANXA1 TRPS1 SGCD PLLP STC1 S100A3 PLCG1 EPO TAF4B DIO2 EIF4B CCNL1 PLEKHA5 AQP2 GNAS STMN3 PPP3R1 JAK3 TP53 HNRNPU CALM1 IFNGR1 ZNF638 ARHGEF7 HNRNPM ZNF407 C6orf62 CDK13 MYNN NAA15 PAWR DNAJC3 DNAJC7 SKAP2 C5orf22 MAP3K2 GALNT7	0.174054	UP
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_DN	PALMD CH25H MEIS1 RUNX1T1 SNN ELK3 FZD2 TNFRSF1B PIK3R3 PATZ1 HEATR6 C2orf68 ZFP36L2 LIPT1 FBXO42 GSTA4 CCNF HOXA3 SIX5 HOXB3 ACBD4 CSTF2T BMP4 HOXA2 PTCD2 HTT FAN1 DHX35 GSPT2 FBXL15 CASP8 MYLIP TMEM50B SUOX BMP2K MECOM FANCF DNAAF2 AGGF1 VWA5A GATA6	0.174065	UP
ZHENG_FOXP3_TARGETS_IN_THYMUS_DN	NR4A2 ADIPOQ MAP4K4 AMPH CADPS EPB41 AKR1D1 APH1A PRSS2 AGR2	0.174094	UP
LANDIS_ERBB2_BREAST_PRENEOPLASTIC_DN	GPD2 ABHD5 CPT2 GDPD3 BCKDHB GNAI1 ACAA2 GSTZ1 PGM1 DECR1 CES3 DGAT1 GBE1 CHPT1 NR1H3 PDHA1 DHRS7 HADHB SCP2 NDUFV1 MCCC1 ETFB ADIPOR2 ATP1B3 ALAD UQCR10 PPP2R5A BCAT2 NDUFAB1 APLP2 CIDEC MKNK2 PTPRB NPC2 CD36 EIF4EBP1 ADRB3 LPIN1 GYG1 ST3GAL6 GHR TMEM43 PENK COL6A3 GPX3 IGFBP6 CXCL12 HTRA1	0.174457	DOWN
WENG_POR_DOSAGE	CYP2B6 CYP2C18 GSTA2 RETSAT ENTPD5 HMOX1 ACOT2 FGL1 ACTG1 LGALSL GSTM2 GADD45B ASNS SLCO1A2 CYP7A1 CYP2A6 GSTM3 ANXA5 LGALS1 VNN1	0.175321	DOWN
REACTOME_GLUCOSE_METABOLISM	SLC25A13 PCK1 PCK2 SLC25A1 PGM1 FBP1 GOT1 PPP2R1B ALDOB MDH2 GBE1 UGP2 PHKB PHKA2 AGL GYS2 PC PFKFB2 SLC25A11 SLC25A10 PRKACB PYGB GPI ALDOA PGK1 PFKL PPP2CB MDH1 TPI1 ENO1 GOT2 GAPDH PPP2R1A PHKG2 CALM2 PPP2CA CALM3 PGAM1 PFKFB1 CALM1 PHKA1 SLC25A12 PPP2R5D PFKP FBP2 GYS1 PFKFB4 GAPDHS PKLR PGAM2 PRKACA PHKG1 PYGL ALDOC PRKACG PFKM ENO3 GYG2 GYG1 PFKFB3 PYGM ENO2	0.17562	DOWN
THEODOROU_MAMMARY_TUMORIGENESIS	PTGIS EGR3 IGF2 PDGFRB PROS1 NOTCH4 ASTN2 FGF3 FGF8 MAP3K8 FGF6 FGF4 WNT1 FOXC2 WNT3 LAMB1 JMJD1C KLF15 RREB1 FGFR2 ATP2B1 AGAP1	0.17582	UP
CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP	FOSB ISLR JUNB ZNF532 HSPA2 STAT5B MYC MTHFD2 INSIG1 HARS DRG1 SRSF7 PFKFB1 HSPH1 ACSL1 ACSL3 CD55 HSPE1 UAP1 NEK3 CTH	0.176453	UP
PID_IL8_CXCR1_PATHWAY	PLCB1 DNM1 GNAI2 PRKCB FGR PIK3CG ARRB2 GNA15 PRKCA LYN PRKCG PLCB2 GNA14 AKT1 HCK PRKCE GNB1 CBL PDPK1 PLCB3 CXCR1 RAB5A ARRB1 PLD1	0.17649	UP
REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION	SYT1 STXBP1 SNAP25 VAMP2 RIMS1 RAB3A SLC6A1 SLC6A11 SLC6A12 STX1A GAD1 HSPA8 GAD2 ALDH5A1 ABAT	0.177904	UP
LIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK	HTRA1 RGS16 ST3GAL6 MMD NRP2 KHDRBS3 PLA2G7 GJB4 TNNT2 IL2RG NPPB JAG1 CHD7 AKR1C3	0.177925	UP
REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS	MAD2L1 CDC20 BUB1B CDC23 UBE2D1 UBE2C UBE2E1 BUB3 CDC27 ANAPC5 ANAPC1 CDC16 ANAPC10 ANAPC2	0.178304	DOWN
WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP	UGT2B17 CASP7 SLC16A1 TFF3 DMBT1 UPP1 PLAC8 GK SERPINA1 CTSS CASP1 LY75 TFRC PSMB8 PDIA4 CXCL6 PSMB10 TAP2 ARG2 CTSC AMBP HLA-B HLA-C B2M STAT1 PSMB9 CCL5 CELA1 C6orf10 UBA7 FLOT1 GBP1 GAST TLR2 SOCS1 SERPINI2 CD14 KRT16 LYN DEFA1 SP110 AIF1 HLA-DMB HLA-DRB1 HLA-DMA GATM IFI44 BST2 HLA-DQB1	0.178813	DOWN
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2	PEG3 VNN1 TAGLN LYVE1 ATF3 CAV2 MAL LPL DFNA5 MCAM CD93 MEOX1 LGALS1 KCNJ8 TUBB2A PFKFB3 ACSL4 SPARC CTSG SIRPA BTG2 MAP4K4 FSCN1 IER3 NAP1L1 GJC1 AKR1B1 DUSP6 CCND1 CD40 TGFBR2 RBP1 DDX25 VAMP5 BMP7 RUNX2 PNPLA3 TPM1 BTG3 FGD1 XYLT2 NPDC1 TLE6 NENF PAQR4 ROGDI TRIB3 B4GALT6 SLC12A4 DLG4 ZFP37 DDIT3 CD14 UAP1L1 MYO9B ABCD2 S100A11 POFUT2 UNC119 MYO7B TUBA8 SLC1A4 DMC1 COL4A4 ABCC5 MVK IL1RN CYP39A1 CKLF GRIA3 CHMP6 FKBP11 MORC4 TWF2 RRM2 DNAJC10 CERK TAGLN2 NOL12 ANXA9 PDGFA DYNLL1 PTTG1 RPAP3 APP ACBD3 PTPRE SEL1L3 MCM2 PAWR TNFSF13 ANXA2 POLD4 SCN8A SOX4 EIF2AK3 COX5B TAX1BP3 HEPH PNLIPRP2 PSRC1 DDR1 STT3A ABCB1 TSPAN8 PRSS8 UPP1 GOLM1 PLS1 SMPDL3B HIST1H1C SLC39A4 ZG16 BCL2L14 HMMR C5orf30 ERI2 KIAA1324 ABHD5 HSD3B2	0.178866	UP
ZHAN_MULTIPLE_MYELOMA_HP_UP	GBA3 SCYL2 RSAD2 SCAPER CCRL2 PIP5K1B PAK1 CSNK1G3 TNFSF10 THG1L XRCC4 SIDT1 F2R FRZB RBM4 ATP5L KIAA0141 POLR1D CNTN5 GTF2F2 DDX58 RC3H2 IPO7 RPL13A RPL7A RPS17 RPL37 CDV3 GLTSCR2 CCR5 EPHB1 SEMA4D LAG3 FCHSD2 OAS2 FLI1 GNG11 LAMP3 AMIGO2	0.179527	DOWN
ZWANG_EGF_PERSISTENTLY_DN	SLC16A5 PCK2 TSPAN1 PIGV ACOT11 ABCC3 ORMDL2 ANKH FANCL HOOK2 MACROD1 EYA2 DNAJC17 MARCKS RPE POLD4 HECTD3 ITPR3 DALRD3 PGAP2 EPHB2 KLHDC2 SLC2A9 CTC1 EPB41L1 DHPS LSM14B SLC6A14 ALOX5AP ERVMER34-1 RWDD2B RFC1 UNC93B1 MTRR MILR1 FARS2 NBEAL2 SYN3 GJA1 HSD11B1 DOCK10 ARHGEF10 FHOD3	0.179776	DOWN
REACTOME_METAL_ION_SLC_TRANSPORTERS	SLC39A4 SLC39A8 SLC30A1 SLC30A5 SLC31A1 HEPH SLC39A2 SLC39A7 SLC39A1 SLC11A1 SLC30A3 SLC39A6 CP	0.179954	DOWN
FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN	CCL11 DCLK1 USP13 GFPT2 ABCA8 TWIST1 RUNX3 CD34 ODAM PLCG2 SPI1 TSPAN5 FLT4 MATN2 MFAP3L IL2RA SGCG PTGES SYP KLF1 CABIN1 KLK2 PICK1 GPD1 ROGDI LHB CYTH3 HOXD11 CD33 ASGR1 IL24 F5 E2F5 RAD51B MATN1 KCNQ2 RNF32 CDH16 CD38 BAP1 CBL VAV2 DIO1 KLHL9 RANBP10 KLRD1 TRIP12 KRT34 IRAK1 ME3 FRZB STYXL1 MAPK3 MLPH PTPN4 BAK1 PCSK6 JUP FCGBP BMP5	0.179999	UP
VERRECCHIA_RESPONSE_TO_TGFB1_C3	IGFBP5 LAMA4 RHOQ ZYX MMP19 NME2 RND3 RHOA CD59 PXN ITGB5 IGF2R APC IGFBP2	0.180841	UP
PID_IL12_2PATHWAY	FOS HLX CCL3 LCK HLA-DRA CD4 CCL4 HLA-DRB1 CD3D CD3E CD247 IL2RA CD8A STAT5A PPP3CB RIPK2 IL18R1 IL1B CCR5 IL2RB RELA IL2RG SOCS1 STAT4 NFKB2 CD8B IL12A FASLG PPP3R1 GADD45B MTOR TYK2 IL12B IL1R1 IL12RB1 MAP2K3 TBX21 STAT3 IL18RAP GZMB STAT6 NOS2 JAK2 STAT1 ATF2 RELB B2M IL2 CD3G PPP3CA IL4 IFNG RAB7A GADD45G IL12RB2 NFKB1 HLA-A MAPK14 SPHK2 GZMA MAP2K6 IL18	0.180867	UP
LEE_LIVER_CANCER_E2F1_DN	NETO2 REG1A ABCG2 RARRES1 PXMP2 OTC AQP8 PCK1 ZG16 C4BPA GOT1 FABP1 EFNA4 DBI AKR1C1 NR1H3 ME1 PPCS ADIPOR2 EGFR CCDC90B MDH1 OAT ALDH1A1 ORM2 ACSL1 HSD17B10 GSTO1 IL1RAP LECT2 CYP2F1 MCM10 HAL PNLIP BHMT REPS1 CYP2E1 BAAT PNLIPRP1 HPD AASS ORM1 ELANE CTRC TMEM222 MAPKAPK2 DCT HAO1 AKAP11 KLK5 GHR GPR37 HSD11B1 RGN IGF1 KYNU TDO2 SERPINF1 CFHR1 ELOVL5 ITPR1 CFH	0.181257	DOWN
REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS	AP1S2 ELMO1 FYN DOCK2 LCK PACS1 CD4 CD247 CD28 CD8B HCK PAK2 AP1B1 AP2M1 B2M AP2S1 AP2A2 AP1S1 ATP6V1H ARF1 AP2B1 HLA-A RAC1 AP1G1 AP1M2	0.181678	UP
REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	VIP RAMP1 FZD7 FZD2 GNG11 FZD4 GNB5 RAMP3 GNG3 RAMP2 CALCB FZD10 PTHLH FZD3 WNT2B FZD9 GNG7 WNT11 CRH WNT7B WNT10B IAPP SCT WNT1 WNT8B PTH1R CALCRL VIPR2 WNT4 FZD8 GLP1R CRHR2 GNB3 SHH FZD1 SCTR WNT2 GIPR WNT7A SMO GNAS ADCYAP1 ADCYAP1R1 GLP2R GIP WNT3 ADM2 GCGR PTH GNG4 GNB1 PTCH2 PTCH1 GNG13 CALCA GHRHR GNB2 GHRH PTH2R GNGT1 FZD6 ADM WNT16 GNG5 CD55 WNT6 VIPR1 IHH WNT5A GNG12 FZD5 GCG	0.181802	UP
TANG_SENESCENCE_TP53_TARGETS_DN	CTH PBK PRC1 CENPA KIF4A TTK NEK2 KIF11 CCNA2 TOP2A KIF20A CDC20 CCNB2 TPX2 EZH2 ZFY FBXO5 PLK4 CENPE KIF23 LMNB1 NUSAP1 RACGAP1 FOSL2 CDK1 SMC4 TK1 NCAPG BIRC5 UBE2C MRE11A TFAM SPAG5 AURKB PTTG1 IL12RB2 BUB1 DBF4 OR1E1 TREM1 KIF20B QPCT HIST1H2AL EXOSC9 NUP62 CDC25A MAF BARD1 NRGN PPL TCF4 PDP1 ADARB1 MAP1B IGFBP5 ADH1B	0.182241	DOWN
LAIHO_COLORECTAL_CANCER_SERRATED_DN	PIGL ERBB3 TRIM31 ATP7B STX3 NEK3 ZNF518A ALDH7A1 ACVR1B MED14 PHKB SLC26A6 FMR1 KATNB1 REPIN1 EPHB2 PROSER1 CDK16 HOXB5 CCNJ ETS2 ERAL1 ZNF263 PCMTD2 MPHOSPH8 KHSRP ATF7IP RAB15 PEX5 ENGASE FBXO46 ECHDC2 NFATC2IP UPF3A HUWE1 MED12 CDK5RAP3 PTCH1 LRP6 RPL37A GTF2IRD1 NIPSNAP3B RPL18 MTA1 STX16 AKAP17A ZNF652 KDM5C SRRM2 PABPN1 POMZP3 SMARCC2 PHF8 OGT ATN1 CCDC9 CLCN7 CPNE1 BRD1 APBB3 SH2B1 SPOP PRRC2A GFOD1 ADD1 GRINA SIN3B ELMO2 ASXL1 TNPO2 GABRE ZFP36L1 RCBTB1 SCAF4 DLGAP4 INPP5D	0.182365	DOWN
REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1	PRKAA1 PRKAB2 PPM1A PRKAB1 CAB39 PRKAG2 PRKAG1 STK11 STRADA CAB39L PRKAA2	0.183174	DOWN
REACTOME_GLUTATHIONE_CONJUGATION	GSTM4 GCLM GSTA2 MGST3 MGST2 GSS GGCT CNDP2 GCLC GGT1 OPLAH GSTP1 GSTO1 GSTM1 GSTA3 GSTA4 GSTA1 GGT5 GSTM5	0.183354	DOWN
WANG_HCP_PROSTATE_CANCER	MEIS2 ATF3 RGS2 CCDC69 HTRA1 CDKN1C FN1 CYP1B1 DUSP1 FLNC PPP1R15A EFEMP2 LAMP3 NEFH FGFR1 TWIST1 PITX1 GRB10 NR3C1 ST3GAL6 AEN ZNF580 MSLN STC2 TFEB IGFBP3 REC8 TCFL5 SGK1 ZNF160 INHA PSCA AHNAK GLTSCR2 SH2D3A CSPG5 B3GAT3 MAPK8IP3 E2F1 SPTAN1 TXNIP UBXN1 BPGM CLIC3 SIM2 CEP57 TAF1D SHMT2 GADD45B MORC2 RHOD RPS21 RPL28 FUBP1 ZNF419 PNMT CDK10 FOXO3 CD2BP2 LONP1 VPS37C SYT17 GAD1 AFF1 S100P DGKD CRAT DNAJB2 CCNA1 JRKL MUC1 CITED2 B4GALT1 NEBL AASDHPPT ASS1 GSPT2 SIDT2 NCOR1 HSPA9 PDLIM5 CRIP1 GTF2H1 CD55 FOSL2 AUTS2 FTH1 PRDX2 BMP2K SECTM1 ABCA5 WNT5A TACC2 FAM134A PDXK CTSA NAMPT WWC1 HIST1H2AG TP53I3 SOCS6 TUFT1 CEACAM1 SLC39A8 GPRC5A HOXA9 RARRES1	0.183842	UP
MCCABE_HOXC6_TARGETS_DN	DCN VCAM1 FAM49A PLXDC1 TNFAIP8 APBB1 ZNF536 CNTN1 PDGFRA SLC44A1 ZBTB7C FGFR2 PAK1	0.183946	UP
LEIN_CHOROID_PLEXUS_MARKERS	MGP SULF1 PCOLCE2 CFH FXYD1 LEPR CSRP2 PLTP F13A1 PCOLCE FZD4 MXRA8 LUM EFS FADS1 ST6GALNAC2 COL8A2 RBP1 LBP TGFBI COL9A3 CARD9 CAB39L PBXIP1 MYO7A DUSP22 DNALI1 CDH3 ACACB TBC1D9 C21orf62 NOTCH2 CCND3 WFDC2 KDR TXNIP F5 STRA6 TRPV4 KL ABCA4 MSX1 SLC4A5 ACE NID2 FOLR1 KCNE2 NEK11 COL8A1 ATP6V0E1 TTR PRLR HEMK1 GC SLC6A20 CLDN1 SLCO1C1 TCN2 ITGB5 EPHX1 CTSC SOSTDC1 EZR LRP10 LGALS3BP SYNE2 PGPEP1 SPINT2 ACAA2 RBM47 CALML4 PERP ACAD8 GGH ADH1C STEAP1	0.183996	UP
LEE_AGING_CEREBELLUM_DN	CYR61 TNC TCEA2 DPYSL2 PTPRM CREM ITM2A FSCN1 CD4 NAB2 CCND1 DBP CYP21A2 SERPINH1 GALK1 HIST1H1T MAF ACTA1 ACHE MERTK WWOX PABPC4 CACNG1 HGFAC MYL7 SNCA SLC6A15 FABP3 IGF2BP3 NFKB2 CSF2 USP4 MYL4 TUBA8 LIN7B LBX1 CLIC3 SNCB NR1D1 MYH7 UBA7 MEF2A OCA2 CNP SLC4A1 MTOR FABP7 PRDM5 DOC2B ACTR1A DHX38 CRYGA DDX47 CAMK2G PISD SMARCA4 NOS2 FARSA CARS CTSE USP46 VAMP3 JRK ANXA7 CD320 HSPA4 THBS1 RAB4B TAOK3 PTPRD NAPA NPY1R XIAP G6PC ADRA2A REG3A PCK1 COL17A1	0.184742	UP
MCBRYAN_PUBERTAL_BREAST_3_4WK_UP	CYR61 GAS1 CNN1 FGF13 CLU HSPB8 SFRP1 ID4 TNC MYH11 EGR2 EDNRA TIE1 LTF FN1 CDH5 EFEMP1 SPP1 RASSF2 TRPS1 P2RX5 DNM1 BASP1 CSPG4 COL16A1 CD248 TGFB3 FSCN1 TMEM109 GATA3 TFAP2C MAFB FADS2 INHBB HSD11B1 HLA-DRB1 MFGE8 MRC2 PTN DBP GJA1 C20orf27 CLDN10 STC2 GSN PTPN14 TNFRSF12A GABARAPL1 KIT ATP1A3 ALDOC GM2A MAPK8IP1 PHLDA1 PLK2 ANO1 KCNB1 ATP6V1B1 CYB5R3 WFDC2 GMPR COL9A1 APOC2 SPRR1A UNC119 MMP14 FZD1 HK1 CHI3L1 CSN3 OGT COMT CITED1 AQP5 SOX13 GSTA3 GABRP LY6D PRPF19 SRPX2 HAL DNAJC12 PRKCE ACLY ACACA COL8A1 COPS2 RAB27B KRT7 HDAC11 LALBA TACSTD2 KRT14 RNASE2 BMP1 ATP6V0A1 FGG SLC38A10 CUX1 ETS2 BTN1A1 CSN1S1 CXCL14 GADD45A LRRK1 HAS2 SLC15A2 RUNX1 SIAH2 ELF5 SLC2A5 C2CD2L LRP5 PDK1 GAB1 ADM CDK1 PGAP2 CD55 LIPG TGIF1 CARHSP1 TMEM51 CRK NFE2L3 PRKACB CYP2D6 MLPH CDKN2B MKRN1 LGALS3 ITFG1 LCN2 GYS2 CLDN3 ATP8A1 ANKH SOX9 LIMA1 ST14 TMEM2 ABCC3 RAD51AP1 MTCH2 IGFBP2 SLC12A2 WWC1 EPCAM SCD TSPAN8 ACSF2 SLC25A24 FXYD3 DLAT KRT18 KRT8 SOCS6 KRT19 TMPRSS2 GALC IRF6 CDH1 DSP TJP2 ELOVL6 CEACAM1 SLC39A8 PADI2 MYB SDC1 PERP CDCP1 TFCP2L1 FOXA1 ESRP1 EHF HSPA1B	0.184767	UP
FRIDMAN_SENESCENCE_DN	EGR1 LDB2 CDC25B LAMA1 COL3A1 BMI1 WISP1 E2F4 ALDH1A1 ID1 MARCKS CCNB1	0.18509	UP
CUI_GLUCOSE_DEPRIVATION	OCLN PBK GFPT1 ARNTL PCK2 SGK3 GOT1 SEPHS2 NEU1 SLC33A1 ELF3 NDUFB3 TFRC EIF2AK3 SLC35B1 TXNRD1 PDIA4 PRKCZ DNAJC3 TGIF1 CDT1 PIGA KDELR2 CDK1 PDIA3 HIST1H4J PDIA6 FKBP2 CANX GADD45A PREB CALR CCPG1 GFAP PYCR1 RRM2 SARS RELB PPIB ART3 SEMG1 ASNS PPEF2 KCNF1 TXNIP SLC3A2 CLGN PRAME FUT1 ZAP70 CBR3 DDIT4 CXCL2 TRPS1 DFNA5 KIF5C	0.185162	DOWN
LINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q	CORO2A PTPN3 ENDOG SLC35D2 FBP1 FKTN FOXM1 ACO1 ANKH RAB14 NANS SLC35A5 TOR1B APTX SPTLC1 PNPO ISCA1 GLE1 TMOD1 SECISBP2 RAD23B FBXW2 KDM5D SMC5 STX17 GOLGA1 VPS13A CUL5 RXRA FAM206A ERP44 POLE3 ASS1 CDK9 FUBP3 KIF2A PSMD5 GPR107 GNAQ PPP6C PSMA2 SEC16A SEC61B KIAA0368 TRIM52 PSMB7 C9orf78 TOPORS TOR1A EPRS ARPC5L CREBL2 ABL1 UGCG PRPF4 KLHL9 NUP214 MIS12 IPPK RARA TSC1 TRIM32 ATP6V1G1 ISCU IARS DDX3Y RNF38 TGFBR1 RPL35 SET SLC2A8 SETX ZNF79 XPA MTAP NUDCD3 ANP32B SMARCA2 TNFRSF10C NUP188 CDK5RAP2 ITPR2 DUSP22 RABGAP1 CNTRL ASTN2 PRKCQ CAMSAP1 ANK2	0.18572	DOWN
CUI_TCF21_TARGETS_DN	HSPA1B IQGAP2 GALC SCD CLIC5 SLC12A2 PARP4 EGF CD55 ADM GABRA4 COL4A3 HSPA1A ART3 PTGER4 PDE10A TLR4 NPHS2 LRRFIP1 UMOD MERTK SEMA3E TSPAN2 MAPT	0.186526	DOWN
MAINA_VHL_TARGETS_DN	CTGF ENO2 BHLHE40 BNIP3 SPARC CCND1 MAF PSG1 GNG4 GAL3ST1 VEGFA SLC16A3 MXI1 GBE1 F3 TNFSF10 DECR1 CLDN4	0.186694	UP
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP	UCHL1 AMIGO2 CH25H RBPMS ARMCX2 CD200 IFI16 CREM GDF15 ERG MAGED2 DUSP6 HOMER3 PNRC1 PHLDA1 HSPB1 TM4SF1 ALDH1A2 CRHBP ECM1 NTS CYP1A1 GBP2 KLF6 VCAN IL1RN SLC7A11 LILRA2 NRCAM ACSL1 PLAT ID1 TMEM176B TCF7L2 ANXA2 SOX4 DDR1 ZNF217 QPRT MALL IL17RB P2RX4 EMP1 NQO1	0.187179	UP
BARRIER_CANCER_RELAPSE_NORMAL_SAMPLE_UP	LRRC31 MAP7 GCG CEP70 IL1R2 SNX4 ALDH3A2 FAS PRKACB AMPD1 ATP5C1 AMD1 CLINT1 RAB27A GGT1 PYY TFAM C12orf4 PRKAG1 PTGER2 CREBL2 ADAM28 NF2 CHGA RNGTT MAPRE2 CPA3 LRMP NDNF ITM2A IGF1 CLIC2	0.187673	DOWN
VALK_AML_CLUSTER_15	TUBB6 MEIS1 SFXN3 ARHGEF3 BASP1 HOXB2 CD52 FADS1 SH3TC1 DRAM1 TBL1X GNA12 HSPB1 GRAMD1B KLF9 EPB41L2 ATN1 ECHDC2 NDFIP1 RUNX1 TNS3 HOXB5 IGF2BP2 SEL1L3 CTNNA1 CEACAM8 HOXA10 SUCLG2 SLC16A1 HOXA9	0.18827	UP
KEGG_N_GLYCAN_BIOSYNTHESIS	MGAT4A MGAT4B MAN2A1 STT3A ALG6 ALG13 DOLPP1 MGAT2 MAN1A1 DAD1 DPAGT1 B4GALT3 DPM3 ALG5 DDOST ALG8 ALG3 ALG9 DPM1 GANAB B4GALT1 MAN1B1 RPN1 DPM2 RPN2 MGAT5 MOGS ST6GAL1 MGAT3 ALG12 MGAT1 MAN1A2 B4GALT2 FUT8 MAN2A2 TUSC3 MAN1C1	0.188502	DOWN
HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_UP	ARHGAP29 RBMS1 LBH ZNF512B HLA-DQA1 NFATC1 CALU RUFY3 ZNF304 SOX11 CRMP1 TCFL5 CREB3L2 TBC1D9 MTMR9 PLCXD1 BCL11B SH3GL1 DIDO1 DSC3 KDM4B TCEB3 YRDC PISD KCNN1 PSME4 MTF2 ZNF263 PNN SNRNP27 CHCHD7 PPM1B EFNB2 TRIM24 SPATA2 ABHD3 BTBD3	0.188927	UP
AMIT_EGF_RESPONSE_240_HELA	AKAP12 RGS2 ZEB1 PCDH7 RBMS1 GFPT2 FGF2 CREM IL7R DLGAP4 FHL3 SYDE1 SH2B3 LRP8 CDK17 TM4SF1 EHBP1L1 EHD1 PLK2 EPN2 CAPRIN2 TPM4 ELL2 IL11 GJB3 THOC1 SOX13 ARPC4 SLC7A11 RPS6KB2 SHB MAT2A TNFRSF1A VAV2 DKK1 ARHGDIA BCL3 FARSA TUBGCP2 RYK TOP1 NUP160 YY1 TBX3 THBS1 YKT6 EZR SDC4 PDLIM5 CD55 ARF6 SPRED2 LETM1 TXNRD1 DNMBP ING2 NDRG1 GRAMD3	0.189038	UP
COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN	UGT2B15 HMGA2 SLC25A13 CYP51A1 DHCR24 CXADR ENTPD5 SELENBP1 HPGD ALAS1 CDA IDH1 HMGCS1 CBS SLC9A3R1 GK ABCB1 GCNT2 ACVR1B ABCC3 CTNND1 ALDOB PPFIBP2 RAB17 CHKA GPT C1orf115 ALDH3A2 MSMO1 GSS LGALS3 DHRS1 SCP2 LPIN2 FDPS BMPR2 TMEM127 SLC35C1 DHCR7 SREBF2 EPS8L2 PCYT2 RAPGEF2 SULT1E1 CYP3A7 ACSL3 ALDH1A1 GADD45G GADD45A DUS1L NDEL1 HCN2 GSTO1 SERPIND1 RELB PRG4 JAG1 GRHPR TM7SF2 GSDMD STX5 RSC1A1 PCDH1 SH3BP2 HIPK2 DDX28 GADD45B SERINC2 ARID3A HAMP MOSPD3 SLC2A8 LRP1 HABP2 SLC25A37 GLUL SLC26A1 HCRT SPRR1A OSGIN1 MAPRE3 HIST1H2BN ZFP36L2 TRIB3 TNK2 DUSP3 BAG3 C19orf60 CA8 GPD1 TSC22D2 NFKBIA FGF8 SLC23A2 TGM1 DYRK3 GSTA1 UBE2L6 CPN1 LDLR IGFBP3 ACVR1 IGFBP4 SNAI1 SVIL TSPYL2 DUSP6 STOM COL18A1 ARID5B ALCAM SORBS2 ARHGAP6 CXCL12 RHOB	0.189664	DOWN
PID_SYNDECAN_1_PATHWAY	COL14A1 COL5A2 MMP9 TGFB1 COL15A1 COL6A3 COL4A1 COL1A1 COL6A2 COL1A2 COL16A1 COL6A1 LAMA5 COL8A2 COL5A1 COL7A1 COL9A3 COL3A1 HGF MMP7 COL13A1 COL9A2 COL9A1 PRKACA COL11A2 COL2A1 COL10A1 COL4A4 COL11A1 CCL5 COL4A5 PPIB COL8A1 SDCBP COL4A3 COL4A6 MAPK3 CASK MET MAPK1 MMP1 BSG SDC1 HPSE COL17A1	0.190014	UP
KEGG_GLUTATHIONE_METABOLISM	ANPEP GSTM4 GCLM GSTA2 GSR GSTZ1 IDH1 PGD GPX2 MGST3 MGST2 GSS GSTK1 GGCT GCLC GGT1 IDH2 OPLAH G6PD RRM1 LAP3 GSTP1 GSTO1 GSTM1 RRM2 SMS GSTM2 GPX1 GSTA3 GPX4 GSTA4 GSTM3 GSTT1 ODC1 GPX5 GSTA1 GSTT2 GGT5 SRM GSTM5 GPX3 GPX7	0.190107	DOWN
YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_UP	KCNN3 DFNA5 F13A1 TDO2 NCF4 DENND3 VAMP5 SLCO3A1 ANK1 H2AFY2 RAD54L2 NFATC3 MED1 DNAJC8 KRT17 HNRNPC VPS72 TBC1D30 CCT7 SNRPB LY6G6C PEX5 USO1 VGLL1 NARF BDKRB1 BSDC1 WDR13 TKT PELI2 VAPB LCMT1	0.19014	UP
LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_DN	TUBA1A MFAP4 SERPINI1 S100A4 NPTX1 RASGRP2 DOK2 RRAGD CYTH1 MCM3 GADD45B RAG2 MAPK8 HS1BP3 TRAM1 DNAJA1 SAP18 ATP2A3 WDR48 PTTG1 S100A6 SOCS2 POLG2 APC NBR1 ACSM3	0.190152	UP
MCDOWELL_ACUTE_LUNG_INJURY_DN	CAV1 MEOX2 CXCL12 HBA1 FHL1 NRP1 MAPT ICAM2 HLA-DQA1 C5 HLA-DRB1 RBP1 CDH13 CHST2 THBS3 LTBP4 FGF1 SFTPC APLNR ZBP1 CDKL2 SLC9A3R2 PON1 OGT ANTXR1 HEY1 ACVRL1 TP53BP2 CYP2F1 PEX16 NFIX FASN DPP4 PDE4DIP TIMM17A MRPS18B RSU1 BMP2K EPB41L3 ABCG1 LLGL2 ALAS1 ADH1C CYP2B6	0.190166	UP
REACTOME_ANDROGEN_BIOSYNTHESIS	HSD3B2 SRD5A1 HSD17B3 SRD5A3 CYP17A1 HSD3B1 CGA SRD5A2 LHB POMC	0.190361	DOWN
REACTOME_SHC_MEDIATED_SIGNALLING	NRAS MAPK1 KRAS SOS1 CDK1 MAPK3 MAP2K2 YWHAB GRB2 MAP2K1 RAF1 SHC1 HRAS SHC3 SHC2	0.190549	DOWN
NIELSEN_LIPOSARCOMA_UP	CLEC3B TNXB GPRC5B C10orf10 CLDN5 STC1 PALM CPZ RNASE1 APOA1 WNT2 SERPINB2 LGMN UAP1 POR HSD11B2	0.190599	UP
PID_S1P_S1P1_PATHWAY	PTGS2 S1PR1 PDGFRB PDGFB GNAI2 GNAZ GNAO1 PLCG1 SPHK1 PLCB2 ABCC1 KDR ITGB3 RHOA ITGAV VEGFA GNAI3 RAC1 MAPK3 MAPK1 GNAI1	0.190633	UP
BIOCARTA_EGFR_SMRTE_PATHWAY	ZBTB16 NCOR2 MAP3K1 RARA THRA MAP2K1 THRB RXRA MAPK14 EGF EGFR	0.19065	UP
MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_DN	DEGS1 CBX7 SLA IL6ST HIP1 CREB3L2 PTPN22 KLF6 PVR GAA HSP90B1 HSPA5 ITGB5 WDR13	0.190695	UP
KASLER_HDAC7_TARGETS_1_UP	AKAP12 NR4A1 FILIP1L PBX3 DUSP10 ELK3 TGFB1 RFTN1 BCL6 CPEB1 DUSP2 ITK CYTIP ST3GAL5 PIK3CD NRGN GPR65 C5 MFGE8 ABHD8 CHST10 SEMA4D LSP1 SIT1 TRIB1 AEN CYFIP2 CHST2 CD247 IKZF1 BCL2 CCR4 ZAP70 CD28 LEF1 ENO3 GSN SLCO3A1 CD6 STAT5A MIER2 DNMT3A IRF4 GM2A CD96 DAPK3 ABCB9 PICK1 AHSG RHOBTB2 TESK1 LTA CAPN3 PDCD1 ARHGEF2 ENDOU BPGM PEX6 HDAC5 TG BCOR USP19 DGKZ RBFA WDR82 HIP1R TEC SBF1 PPP5C PLA2G6 SSR2 ZBTB7B CDK2 ASB6 RARA MTSS1 MUL1 PTGER4 ITGB3 MEPCE TMEM57 PIAS4 HMG20B HSPBP1 ZC3H11A RASAL1 NCOA3 MAZ P2RX7 STAT3 PHKA1 PIN1 TOMM40 CNNM3 TDP1 UGCG RNF187 UBXN6 CUTA BMP4 FGD2 CCR8 FARSA TSC22D1 GRB2 OSBPL3 ERP29 FASN CLSTN1 PKNOX1 MRPS2 VARS DFFB DDX21 FBXW11 GPAA1 PCYT1A RAB1B CAP1 ASB8 B4GALT1 H2AFY DDX19B RUNX1 U2AF2 CAPN7 C2CD2L POLDIP2 B4GALT3 FBXL6 LRP10 AKAP1 DAD1 NPL CYP20A1 ATP2A2 MRPS11 PIGT SGSM3 CLPTM1 LMAN2 FRYL RPS6KA1 NCOA2 UNC119B WSB2 IDE TMEM2 GPN2 NHEJ1 PKP3 STEAP3 GALC CDH17 MARCH3 GLTP	0.19074	UP
BALDWIN_PRKCI_TARGETS_UP	RHOB MPDZ SDC2 TRIB2 ATP2B4 TDO2 WISP2 CBX6 ADA SLC4A7 NOV NEK9 OXTR PAK2 MEF2A ATP6V1G1 IFITM1 MAZ EIF1AX HFE AQP9 TGOLN2 SLK TMEM106C FOSL2 SLC35A5 SEPT11 EIF4EBP2 GMFB SLC11A2 TFDP2 TSPAN6 MPP5	0.190876	UP
KEGG_BETA_ALANINE_METABOLISM	EHHADH HIBCH ABAT ALDH7A1 ACADM HADHA ECHS1 MLYCD ALDH3A2 ALDH2 ALDH9A1 GAD2 DPYS GAD1 SMS ALDH1B1 AOC2 UPB1 DPYD SRM AOC3	0.19095	DOWN
MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_7	PTGDS BGN STK3 ARHGEF2 NFKB2 ZNF593 TP53 KAT7 PCBP1 RPL41 PPP1R8 DDX21 CKAP2 NCKAP1	0.190962	UP
BIOCARTA_CELL2CELL_PATHWAY	CTNNA2 PECAM1 ACTN1 VCL ACTN2 CTNNA3 ACTN3 CSK PTK2 CTNNB1 PXN SRC CTNNA1	0.191036	UP
REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC22A4 SLC44A4 SLC22A5 SLC16A1 SLC39A4 SLC39A8 SLC22A18 SLC5A1 SLC6A9 SLC30A1 SLC30A5 SLC31A1 HEPH SLC2A10 SLC2A1 SLC39A2 SLC16A3 SLC13A1 SLC2A5 SLC2A9 SLC44A1 SLC2A4 SLC22A3 SLC6A20 SLC39A7 SLC5A7 SLC22A2 SLC14A1 SLC6A3 SLC39A1 SLC18A1 SLC18A2 SLC11A1 SLC13A2 SLC30A3 SLC6A14 RHCG SLC22A11 SLC5A2 SLC14A2 SLC6A7 RHAG SLC2A8 SLC2A11 SLC22A1 SLC16A8 SLC22A7 SLC22A6 SLC6A5 SLC6A12 SLC6A11 SLC6A6 SLC13A3 SLC6A15 SLC6A2 SLC2A2 SLC6A1 SLC22A8 SLC39A6 SLC2A6 SLC2A3 SLC16A7 SLC47A1 CP	0.19122	DOWN
HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2	CCNA2 RAD50 CCNB1 KRT8 TOP2A MKI67 SKP2 EGFR BIRC5 MDM2 PGR TP53 KRT5 CCNE1 CDKN2A BCL2 CCND1 VIM	0.192705	DOWN
REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS	CASP7 CASP3 APAF1 XIAP BAK1 CYCS BAX TFDP1 CASP8 BAD YWHAB BCL2L11 DIABLO BID DYNLL1 CASP9 BCL2L1 PMAIP1 GZMB MAPK8 TP53 PPP3R1 NMT1 AKT1 E2F1 BBC3 BCL2	0.19315	DOWN
KEGG_PPAR_SIGNALING_PATHWAY	EHHADH HMGCS2 PPARG ACOX1 SLC27A2 CPT2 PCK1 PCK2 MMP1 ACADM SCD GK ACSL5 ACAA1 FABP1 CPT1A DBI PPARA NR1H3 ME1 FABP5 PPARD SCP2 ACOX3 CYP27A1 AQP7 RXRA ACSL3 APOA2 ACOX2 ACSL1 CPT1B FABP2 PDPK1 UBC GK2 CYP4A11 FABP7 UCP1 RXRB APOC3 CD36 CYP7A1 ACADL OLR1 ACSL6 FABP3 APOA1 RXRG SLC27A5 FABP6 SLC27A6 ILK ANGPTL4 FADS2 PLIN1 SCD5 ACSL4 SORBS1 PLTP LPL ADIPOQ FABP4	0.193156	DOWN
REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS	AP1M2 AP1G1 SORT1 TBC1D8B CPD VAMP8 TPD52 NECAP1 TFRC DNM2 ARRB1 OCRL AP3B1 NAPA YIPF6 FTH1 IGF2R VAMP7 BLOC1S1 RAB5C SNX5 GAK CLTC ARF1 PICALM TGOLN2 PIK3C2A SH3GL2 AP1S1 SNX2 CLTA HSPA8 AP4E1 FTL TXNDC5 PUM1 AP3S1 AP1B1 HIP1R VAMP2 TPD52L1 AP1S2 DNAJC6	0.193365	DOWN
PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN	NEFL IL33 PROS1 APBB2 CHST8 CCR4 ADCY8 CDC14A TBXA2R PDE10A STATH OR3A2 GYPA CENPQ GNRH2 PDAP1 SLC10A1 EXT1 MICAL2 NR5A2	0.194334	UP
BEIER_GLIOMA_STEM_CELL_DN	HBEGF GPNMB KLF7 BASP1 LAPTM5 HLA-DQB1 HLA-DQA1 HLA-DRA HLA-DPA1 HLA-DMA HLA-DRB1 CCND1 SUPT3H CUEDC1 HLA-DMB CD74 USP36 IGFBP3 LPIN1 KIAA0930 TIMP2 DUSP3 BTN2A2 MAPRE3 PORCN HIF1AN CACNA1A IFIT5 MINA ZNF717 BCL2L2 EXOC6B TLE3 DLG5 ECD YWHAB INPP1 FZD6 FTH1 DDAH2 MGLL SOS2 FUCA1 DHRS7 SLC11A2 BMP2 GPN2 HNMT GLTP	0.194409	UP
GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP	MS4A1 P2RX5 CD1C PLXNC1 ITGA4 IQSEC1 CYBB LPIN1 GLRX PRKACB SMAGP	0.194667	UP
HAHTOLA_CTCL_PATHOGENESIS	MMP9 MS4A4A CD52 IL7R NKG7 IL2RB KIR3DL2 XCL1 TXK CCL5 TBX21 LILRA5 GZMB DLG5 S100P VAV3	0.194824	UP
REACTOME_PROTEIN_FOLDING	TUBB2B TUBB6 TUBA1A TUBB2A USP11 TUBB4A KIF13A KIFC3 SPHK1 PFDN2 PFDN5 TUBB3 FBXW7 NOP56 FBXL5 TBCD TUBA1B TBCB FBXW4 TUBA3C PFDN1 TBCA TUBA1C ACTB LONP2 CCT3 CCT4 TUBB1 CCT7 TUBB4B CCT2 TUBA4A CCT6A FBXO4 CCT8 PFDN6 VBP1 FKBP9 TCP1 PFDN4 CCT5 TBCE FBXW2 TBCC ARFGEF2	0.194925	UP
BILD_E2F3_ONCOGENIC_SIGNATURE	SYNM REEP1 NEFL PEG10 SOBP ENO2 TNC PCOLCE2 STXBP1 AP1S2 TMEM158 CDKN1C KANK2 TIAM1 PFKFB3 SH3BGR PSIP1 ATRNL1 GNAL RUNX3 KCTD15 CD83 SLC27A3 PLXND1 INHBB TMEM43 TM6SF1 SOX12 EPHA2 TSPAN5 AKR1B1 GPR137B PTGS1 MRAS DVL3 CDKN2C EEF1A2 CHST2 TNFAIP3 KHDRBS3 SLC16A6 NR2F1 LRIG1 MDN1 CHST7 GLRB TPPP TBC1D9 CCP110 SIN3B CIZ1 IL1B ADCY3 DYM B4GALT6 FANCA GPR27 CCND3 CSPG5 NFATC3 PHF2 NIN RRAGD AKT1 CDKN2A DCK FZD1 BCOR CCNE1 NASP RECQL4 DONSON LIN7B PWP1 RAVER2 SIX5 SRSF6 USPL1 GNAS POLE RPL17 DPY19L1 CHST1 CCNO TAF1D PHTF2 RBM25 SSX2IP SREBF1 NAT9 HEY1 SMAD6 KDM4B EPB41L4A RPA1 PHF10 SLC25A12 PIN1 PTCH1 TMOD2 EIF4A1 TEAD4 CHML SRSF7 CRELD2 FEN1 DCLRE1B ATAD2 DGKQ FAM57A RAB15 FBXO21 TMEM214 FAM46A CHD7 ABCC10 RAB26 CRY1 FAM134B WIPI2 NUP155 TAF4 PCNA SFMBT1 NEMF HECA BCL2L11 MFHAS1 POLE2 DNAJC9 AK4 TRIM3 MMP15 NCKIPSD TMEM106C CDK19 TFDP1 SAC3D1 INSR CCNE2 CAMKK2 FGFR3 SLC30A4 FRAT1 SCN8A FAM171A1 FGF9 WNT5A EZH2 PLCL2 ALDH5A1 TMEM97 ZNF195 SCNN1A GCH1 ANKH PRRG4 DDAH1 CAMK2N1 ZWINT SLC9A3R1 PDE8A DTL GINS1 IL17RB FERMT1 CEBPA MYB EPB41L4B C5orf30 PXMP2 LRP4 UGT8 ABCG2 NETO2	0.19506	UP
REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	FN1 VWF TLN1 FGB APBB1IP ITGA2B FGA ITGB3 RAP1A PTK2 RAP1B FGG SRC CRK	0.195092	UP
CHEOK_RESPONSE_TO_HD_MTX_UP	FLNA S100A4 MYLK S100A8 CTSG ARL4C TYROBP ATM S100A9 HHLA1 NFKB2 SLC1A4 DEFA4 LYZ MPO ABLIM1 AZU1 IL32 ANXA2 BAX OLFM4	0.195128	UP
BURTON_ADIPOGENESIS_4	ZBTB16 PEG10 BCL6 COL6A2 COL4A2 COL6A1 COL18A1 PLXND1 ANGPTL4 IGFBP4 ST3GAL4 EPHB4 NOP2 AGTR2 GLUL DPEP1 CSE1L DDX51 PPM1G RCL1 SREBF1 CCT3 EIF2B1 NHP2 LSM3 CERK ZNF706 H2AFX GART BZW2 SNRPA1 FKBP4 LDHA ABCF2 ADIPOR2 TSKU UCHL5 ENTPD6 MRPS12 PPP2R1B IDH3A	0.195261	UP
SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN	THBD FN1 CALD1 RDX EREG NAP1L1 CCND1 DUSP7 TACC1 MYC CDH3 AHNAK SF3A2 PRKAR1A ROCK1 JAK1 PLEC NBN TOP2B RRM2 IGF1R DDX21 THBS1 ID1 PTP4A1 EGFR SEMA3C ITGA6 ITGA2 LAMA3 EMP1	0.195261	UP
HUMMERICH_MALIGNANT_SKIN_TUMOR_UP	LTF S100A8 COL1A2 COL18A1 CCND1 S100A9 KRT16 ECM1 RHOG GSTA4 GSTO1 KRT13 SLPI	0.195272	UP
INGA_TP53_TARGETS	FOS IER3 IGFBP3 BBC3 FASLG TP53AIP1 MDM2 PMAIP1 SESN1 GADD45A PCNA TNFRSF10B SFN THBS1 CCNG1 BAX CDKN1A	0.195303	UP
REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK	PRKAA1 PRKAB2 PPM1A PRKAB1 CAB39 PRKAG2 PRKAG1 TSC2 TSC1 RHEB STK11 STRADA CAB39L PRKAA2	0.195661	DOWN
SMITH_TERT_TARGETS_DN	FOSB ADIPOQ TAGLN NEFL SERPING1 NEFM DKK3 SPEG NME4 THY1 ARHGAP25 PAM SIRPA KYNU HSPA2 ARHGDIB TCF4 GRK5 A2M DUSP6 MMP2 SP110 GAMT GSN L1CAM PIK3R3 ATP1A3 GM2A PML KANK1 TUBB3 TNFSF9 PGF LIPA STAT4 IFI30 UNC119 CALML3 AKT1 TRADD IL1RN RRAGA NID2 ACLY VAV2 APEX1 XRCC5 CD47 DNA2 FAM53B GSTO1 ASAH1 PCNA CHMP1A CDSN PPP1R7 OAT SERPINB6 FAH ABR ATP5O CCNG1 RAB11A NSDHL CPOX VSNL1 IDI1 CAT CLP1 ALDH3A2 RAB40B PON2 UGP2 TNFSF10 SORD PNP AHCY ANXA4 ALDH7A1 CBR1 LAMP2 TST DHCR24 SRD5A1 AKR1C3 EHHADH	0.195772	UP
REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES	PSMC6 PSMB8 PSMD3 PSMA5 PSMD7 PSMD13 PSMB10 PSMD10 PSMD11 PSMA3 PSMC4 PSMD8 PSMA6 PSMF1 PSMD5 PSMB3 PSMA1 PSMA4 PSMD9 FCGR1A PSMC3 PSMA2 PSMA7 PSMD1 PSMB7 PSMD2 PSMB5 PSME4 PSMD14 PSMB6 PSME2 PSMD12 PSMB1 PSMD6 PSME1 PSMB4 PSMB9 FCGR1B PSMB2 CD207 PSMC2 PSMC5 PSMD4 PSMC1 MRC2 MRC1	0.196142	DOWN
ZWANG_EGF_PERSISTENTLY_UP	OASL HMGCR CYP51A1 UGDH HSDL2 POR ME1 LANCL2 IDI1 KLHL7 NSDHL SERPINB7 C14orf1 IFIT3 FAM98A OGDH CXorf57 FAM169A DYNC1LI1 CPA4 RBFOX1 RHOBTB2 CALU RNF216 PRUNE2 TCEA2	0.196253	DOWN
BRIDEAU_IMPRINTED_GENES	PEG3 PEG10 SGCE IGF2 CDKN1C DCN SNURF CD81 SNRPN HTR2A GATM GRB10 NNAT INS NDN ATP10A COPG2 TSPAN32 WT1 ASCL2 FBXO40 MAGEL2 APOC2 DRD1 TSSC4 NAP1L4 GNAS ASB4 RASGRF1 UBE3A QPCT PPP1R9A CALCR RB1 SLC22A2 MKRN3 DLK1 SLC22A3 PON3 TH DHCR7 KCNQ1 IGF2R SCIN PLAGL1 PHLDA2 IMPACT MST1R PON2 SLC22A18 MEST DDC SLC38A4	0.196275	UP
SESTO_RESPONSE_TO_UV_C7	SRD5A1 SDC1 EPHX2 FGFBP1 PCK2 MMP1 CBR1 CDC20 PGD ITGA6 AKR1C1 HSD17B4 RSU1 CDKN3 VSNL1 NCAPD2 KIAA0101 ATP1B3 MT1E AKR1A1 MT1X ADK TK1 PLCD1 CTSC IDH2 ASS1 UBE2C PLP2 XBP1 ATIC CKAP4 MTHFD1 TAF10 ACSL1 ALDH3B2 HSPA5 SLC1A5 ESD MMP10 PTMA LIF PPIB HNRNPA2B1 MLH1 RPL3 HMGB1 PRCP IFITM1 ITGB1 ASNS YARS TCN1 STMN1 EXOSC7 PLA2G4A AARS ODC1 CIRBP ETV2 GSN CDC25B CRABP2 CEBPD PAM LGALS1 BLVRA	0.196635	DOWN
KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	DES DMD ITGA7 TCF7L1 ITGA5 CTNNA2 ITGA1 SGCD SGCA ACTN1 LAMA2 ITGA4 CACNA1C TCF7 CDH2 RYR2 ITGA9 GJA1 CACNA2D1 LEF1 CACNA2D3 SGCG ITGB7 CACNG1 CACNB2 ACTN2 EMD CACNB4 CACNG3 ITGA2B CTNNA3 ACTN3 CACNG2 CACNG5 CACNG4 CACNA1D CACNA2D2 ITGA8 ITGA10 ITGB8 ITGB1 SLC8A1 ACTB LMNA ITGB3 DAG1 CTNNB1 SGCB CACNA1S ACTG1 ITGA3 CACNB3 CACNB1 ITGAV ITGB5 CACNA1F ACTN4 ITGB4 TCF7L2 ATP2A2 CTNNA1 ITGA6 JUP ITGA2 DSP DSG2 PKP2 DSC2 ITGB6	0.196933	UP
GROSS_ELK3_TARGETS_DN	ADAMTS1 PTGS2 BHLHE40 BNIP3 MAFF CXCL2 RAMP3 IFI44 IL6 SOCS3 PLEK HAX1 OAS3 CNOT7 ACOX2 PDK1 COPE FTH1 FAM162A SLPI GBE1 VLDLR PRKG2 PGM1 UPP1 HOXB9 RSAD2 CTH	0.197255	UP
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_DN	GPM6B PLEKHO1 TPPP3 RUNX1T1 FHL1 SCRN1 PDE2A HEG1 FXYD5 SERPINF1 CD200 ARL4C PPM1F CD34 ZNF135 MAP4K1 PPP1R16B TCF7 SVIL PDE4D DENND3 ATP10A DUSP5 INSL3 ABCD1 LTBP4 ESYT1 LDLR CHST7 PRAME SNRK HSPB1 RNF130 EHD1 LAX1 HOXC4 ZMYND10 EEF1D BTN2A2 CAPN3 RETN SUN2 CD7 SPTAN1 POU6F1 ARID3B GJB3 HPCAL1 PI4K2A PDX1 ZNF384 BCAT1 EIF3D OAZ3 LPAR6 RRP9 MEF2A TNFRSF25 PLEKHG3 MOB1A RARA GPR6 RPL28 EIF3F ADAR ACLY MLNR PMAIP1 TCEB1 ZNF287 XRCC6 GAD1 FLAD1 GRHPR UBE2L3 RERE TERF2 DGKD FCAR ZC3H15 PES1 GDI2 APRT TTC21B NBL1 LRRN2 PHB2 UXT FAM134B DSC1 EFCAB1 MPHOSPH6 GNAQ NFYC QARS EIF6 PSMA6 SURF1 PSG9 COPS5 XPNPEP1 EPHB2 TUFM KCNQ1 CS GPI PYGB RAB11A CAMKK2 FAM171A1 ST14 TRPM4 PCSK6 RAB4A SLC9A3R1 ATP9A TMPRSS2 PLCB4 EPHX2 LRP4	0.197555	UP
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN	CHRDL1 RTN1 LMO3 C7 PHOX2B CXCR4 SCHIP1 TMEM158 KCNMA1 MFAP4 RGS13 CADM1 ELMO1 S100A4 EMILIN1 CHRNA3 NME4 PCOLCE FZD2 GNG11 LDOC1 MAB21L1 TWIST1 LUM RPS6KA2 RGS4 ABHD14A PDGFRL ETV1 CDH11 H1FX DUSP7 TNFAIP6 MYC FAM127A TMSB15A LRRN3 BCL11A TFAP2B EID1 TMX4 ALDOC GM2A HDAC9 SLC6A2 NELL1 NUDT1 PPEF1 EXOSC9 CLCN4 MYCN RAPGEF4 RPH3A KIFC1 STMN1 LSM2 CHGA INSIG1 CADPS SPRY2 LAGE3 POLD1 ASCL1 ESRRG VCAN AGPAT1 NFIB DPY19L1 PPFIA4 HMGN3 SIX3 ABCA12 PFKP SLC18A1 SMAD6 TBC1D30 ADCY1 MFSD10 MYOF MARCKSL1 CBX5 SNRPG PLK1 HMGB2 H2AFV RLN2 NHP2 POLR2L TMSB10 LSM7 TMSB4X PDGFRA PEBP1 GTF2H5 APRT HIST1H4C BUB1 COX17 NDUFB1 PTTG1 AURKB LMO1 AK4 UBE2C RPA3 PTX3 BIRC5 PDK1 LDHA NDUFA2 ADM SORL1 METTL7A CDK1 DNASE1L1 AKAP1 CYB5A TRAPPC6A KIAA0101 ESPL1 NFE2L3 ACYP1 CETN3 ICA1 VSNL1 MARCKS MTUS1 KIF23 NDUFB6 ATP5G1 MXI1 SPTSSA FABP5 TFRC MLLT3 DBI SPC25 CD24 IGSF3 DHFR DOK4 MAOA MKI67 CDC20 LIMK2 ALDH7A1 DACH1 TOP2A DLGAP5 HK2 AURKA CCNA2 MAP2K6 DHCR24 CENPA MYB HMMR MAD2L1 BCKDHB SLC1A1 IL7	0.197615	UP
LU_AGING_BRAIN_DN	ANK2 FGF13 CALB2 CAP2 MAP1B TAGLN3 DYNC1I1 PENK CHGB NRXN1 CORO1A THY1 GNB5 MAPT HTR2A FAM49A RBP4 VAMP1 RGS4 INPP4A PRKCB SST GFRA2 ATP6V1G2 TSPYL2 PDE4D B3GALNT1 SCN2B FRMPD4 MAP2 ATP2B2 RAB3A BCL11A CNTN1 GABRB3 MEF2C ACTA1 CDK5R1 SYN2 SLC17A7 PLD3 TPPP PTPRO CACNB2 PRKCG NR1D2 PPM1E ABI2 CRH DUSP3 PITPNB RAD23A SMARCA2 FGF12 CALB1 MEGF8 BRD2 UBE2M HSPA13 CDH22 EP400 GRIA1 UROS FOXG1 OGT MBNL2 C6orf106 PPP3R1 RAN RASGRF1 UBE2S GRIN2A AZIN1 MRPL28 E2F4 MTOR CAMK4 KCNJ9 CAMK2A RANBP9 GABRD CCKBR MAT2A RAP2A TRIM38 CBX5 CALM1 RBBP4 DDX3X TOP2B TUBA4A CALM3 GAD1 ITM2B SARS ELAVL2 ATXN7L3B ENSA KLHDC3 PCMT1 HSPA8 ETS2 YWHAZ TGOLN2 RAB6A GNAQ PITPNA SFPQ ATP6V1H TPBG FKBP1A RAB5A NUTF2 CDC40 DNM1L UBE2D1 MAPK9 SRSF10 MAP2K4 TIMM17A ATP6V1A ATP5A1 RAB1A GORASP2 YWHAE ATP2A2 PRKCZ NAPA CLTB RNF19B NUDT21 NAPG ATP8A1 TNFRSF21 PARM1 PIK3CB RPS6KA3 PLEKHB2 MRPS12 VDAC1 MAPK1 PANK3 KIF1B ITPKA HCCS PAK1 CA4 SLC1A1 C5orf30	0.19765	UP
CHIARETTI_T_ALL_RELAPSE_PROGNOSIS	TTK MELK CAT NDC80 BUB1B CENPF CDC7 H2AFX DEK HNRNPH1 USP1 SEC31B RCBTB2 MEF2A AHNAK LRMP CD8A MYC CD2	0.197651	DOWN
OXFORD_RALA_OR_RALB_TARGETS_DN	CNN1 CLU TNS1 PPP1R3C CALD1 PDE2A PALLD FSCN1 TPM1 SLC4A2 AGRN KRT17 RNASET2 SLC6A8 VEGFA SLC16A3 CA12 METTL2B HK2 PAK1 CD2AP NQO1 TMOD3	0.198326	UP
KASLER_HDAC7_TARGETS_2_DN	ZCCHC24 KLF2 BHLHE40 IFITM2 MPP2 GAMT STC2 BBC3 NFKBIA OAZ2 KLHL24 CUL7 CDH22 P2RX3 GADD45B HYI PTCH1 CACNB3 PYCR1 ACOX2 VEGFA H1F0 ADD3 SEMA6A GPI CDKN1A TACC2	0.198444	UP
PECE_MAMMARY_STEM_CELL_DN	GUCY1B3 NID1 TRPC1 FHL1 WASF3 CALD1 SNED1 GABBR1 GPRASP1 VCAM1 CHN1 DNM1 DEGS1 STX2 COL6A1 BGN FAP SCAF4 RUFY3 ANP32E TROVE2 KLF12 ZNF862 ATRX TPM4 ARHGEF2 NKTR BTBD19 SRSF3 CCNL1 PCM1 TRIM27 TXNIP JAK1 MMP14 REXO2 NASP ARMC8 KPNB1 EPS15 VCAN PNISR KLHL28 RABEP1 CDC5L MARCH7 ITGB1 ZBTB1 HEY1 UBR5 CDC16 JMJD1C TIA1 SEC63 DCTD XRCC5 SQLE TIMM23 SRSF7 CALM1 DDX3X CHD9 PUM2 ANKRD10 JAG1 SLC7A6 KITLG RNF146 MAP1LC3B RGS17 CTSZ NSMAF GDI2 TRIO SLC24A2 RASA1 NEMF IMPAD1 P4HB APP VMP1 CNOT8 SHQ1 PDIA3 DERL1 GLUD1 RUSC1 CTSO TCF7L2 UBL3 ZDHHC6 RPP14 IDI1 UBE2K SPON1 TM9SF2 PLBD1 ANKH EPB41L3 DENND4C PANK3 AK2 CA12 ZKSCAN1 KIFAP3 EMP1 ARHGAP32	0.198667	UP
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13	PEX7 PCCB GSR MRPL13 LYRM2 CES3 EBP MRPL35 NDUFS2 TMED3 CYB5B MRPS33 DBI NDUFA9 DNAJC15 CAT ATP5D CHMP2A C1D UQCRC2 PC COX5B RBM3 ATP5F1 ETFB ILVBL CETN3 PSMA5 COX16 ECH1 PRDX2 NDUFC1 COX6A1 IFNGR2 NDUFB5 COX7B MRPS18A ANXA2 S100A10 TKT C14orf1 NDUFA5 UQCR10 DAP DPM3 NDUFAB1 NDUFA2 TSEN34 SPCS1 UQCR11 MRPL11 ATP5O ATP5J SF3B5 S100A6 POLE3 PMPCB FKBP3 PSMA6 GTF2A2 MRPL23 SNRNP27 CYBA C14orf2 SUMO3 RBM14 TIMM8B PPP1R7 MRPL18 UBL5 CD320 NCBP2 ACYP2 GUK1 NDUFA13 NDUFB8 RAB28 FIBP HNRNPH2 GPN1 C9orf78 NDUFA3 TAGLN2 SHFM1 DAP3 NDUFB11 PRPSAP2 PAFAH1B3 RELB POLD3 LSM3 PSME2 MRPL52 CKAP5 PPIH CUTA ESD SNRPG NEDD8 H2AFZ SNRPE UQCRB PPIB ATP5E ANAPC13 POLR3K RPP30 PPP2R5C SSNA1 PQBP1 HDDC2 PSAT1 PDCD5 MRPL28 REEP5 DYNLRB1 OGFR LAGE3 PARK7 NMT1 FAM49B GPX4 EIF4EBP1 SNRPD2 FAM3C CALB1 HNRNPL DGCR6 ABCC1 B9D1 CUEDC2 C19orf60 NAB1 MTMR9 CCND1 NACC2 SNX10 CSRP1 LGALS1 SMTN CSRP2 ANXA1 ARMCX2	0.198888	DOWN
WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP	ASPM PRC1 NEK2 TOP2A DTL KIF20A PCSK6 FGFR4 CDK1 IL32 MED8 RRM2 SQLE PMAIP1 UBE2S MVK BARD1 NPTX2 SLC2A6 STC1 PDE4B	0.198945	DOWN
BIOCARTA_RANKL_PATHWAY	FOS TNFSF11 IFNAR2 FOSL1 RELA IFNB1 MAPK8 IRF9 EIF2AK2 IFNAR1 NFKB1 TRAF6 FOSL2 TNFRSF11A	0.199049	UP
DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_UP	SHROOM2 LAMB3 ITPKA FAS ELF1 POU2F3 HIST2H2AA3 PINK1 USH2A CTSZ PRDM2 HNRNPU TK2 PTPN22 FXYD2 MUSK HIST1H2AK	0.199306	DOWN
KASLER_HDAC7_TARGETS_1_DN	IGFBP6 SPP1 C3 COL6A3 SEMA4A TXNIP TRIP10 EDEM1 ITM2B PARP16 LGMN IGF2R SLC2A1 TTC19 PMM1 HK2	0.199677	UP