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DESCRIPTION
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DESCRIPTION
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Package: GRETTA
Title: Genetic inteRaction and EssenTiality neTwork mApper
Version: 2.7.0
Authors@R:
c(person(given = "Yuka",
family = "Takemon",
role = c("aut", "cre", "cph"),
email = "yuka.takemon@gmail.com",
comment = c(ORCID = "0000-0002-3538-4409")),
person(given = "Marco",
family = "Marra",
role = c("ths"),
email = "mmarra@bcgsc.ca",
comment = c(ORCID = "0000-0001-7146-7175")))
Description: Genetic inteRaction and EssenTiality neTwork mApper (GRETTA) performs in-silico genetic screens and generate essentiality network maps.
To do this, GRETTA leverages publicly available data generated by the Cancer Dependency Map (DepMap) project. Users can define versions of DepMap
to analyze, and can also query DepMap data directly from the tool. A manuscript with with detailed explanations on GRETTA has been published and can be found here:
https://doi.org/10.1093/bioinformatics/btad381.
biocViews: Genetics, SystemsBiology, Transcriptomics, Proteomics, BiomedicalInformatics, GenePrediction, FunctionalPrediction, GeneTarget, NetworkInference, Network
URL: https://github.com/ytakemon/GRETTA
BugReports: https://github.com/ytakemon/GRETTA/issues
BiocType: Software
Depends:
R (>= 4.2.0)
License: GPL-3
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.1
Suggests:
knitr,
rmarkdown,
testthat (>= 3.0.0)
Config/testthat/edition: 3
Imports:
dplyr,
magrittr,
forcats,
purrr,
rlang,
stringr,
utils,
tidyr,
doMC,
broom,
diptest,
parallel,
rcompanion,
foreach,
readr,
tidyselect,
stats,
ggplot2,
ggrepel,
RootsExtremaInflections,
tibble,
BiocFileCache,
tools
VignetteBuilder: knitr