Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

vcf_validator expects the wrong number of PL values #220

Open
zgoodwin opened this issue Nov 18, 2022 · 0 comments
Open

vcf_validator expects the wrong number of PL values #220

zgoodwin opened this issue Nov 18, 2022 · 0 comments

Comments

@zgoodwin
Copy link

Hi there,

I am seeing an issue where the validator complains about the number of values in the PL field being inaccurate, when in fact, the number of PL values at the specified samples and line numbers are consistent with the number of alleles at the site:

Examples from the validator file (vcf_validator_linux):

Error: Sample #355, field PL does not match the meta specification Number=G (expected 6 value(s)). This occurs 1 time(s), first time in line 1304.
Error: Sample #154, field PL does not match the meta specification Number=G (expected 6 value(s)). This occurs 1 time(s), first time in line 1383.

Values in the VCF file for each line/sample combination (only showing the chrom, pos, ID, ref, alt and PL fields for the affected samples):

chr1     203906  .       G       A       0,0,0
chr1     219447  .       C       T       445,54,0

As you can see, the validator seems to think that these sites are tri-allelic (6 PL values) when they're really bi-allelic, therefore there should only be 3 PL values. Is this a bug or could I be doing something wrong?

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant