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Discussion Notes on Definitions

James A. Fellows Yates edited this page Aug 17, 2020 · 1 revision

Summaries from slack discussions

To what level does a single-genome have to be ‘complete’ in order for it to be included on the list

  • The question originally was whether there was a depth/percent coverage cut-off for inclusion
  • Discussion concluded this was a subjective measure and we do not currently have a field-wide 'standard'
  • Outcome:
    • 'Fallback' to the practical definition of: if a paper reports it as genome we can include it.
    • Concept being: be as inclusive as possible
    • But, this list does not make statements on quality and researchers still need to do their own QC

Papers re-analysing data used for other purposes

  • While we support data re-analysis (e.g. metagenomic analysis of samples originally used for WGS studies), this is currently problematic how to list papers like this:
    • how to correctly attribute the data? Should both or just original data depositor be cited (however then link with metagenome is hidden)
    • how to prevent inclusion of all ancient samples (given they are intrinsically metagenomic) ever published, given the thousands of samples studied in ancient pop-gen
  • Outcome:
    • Only include metagenomic studies generated and deposited own data
    • Or samples that implicitly 'metagenomic' (e.g. microbiomes from shotgun sequenced dental calculus), even if original purpose was for other research (e.g. retrieving human DNA for pop-gen analysis)