DMRichR v1.2.0
New functions and critical maintenance updates have been made alongside many minor improvements.
The two new key functions are:
-
methylLearn()
was developed by @hyeyeon-hwang and utilizes two machine learning algorithms to perform feature selection and identify the top common DMRs. It produces an html report and a heatmap. -
smoothPheatmap()
replacessmoothHeatmap()
, where it plots traditional Z-scores and also offers improved aesthetics for multiple covariate annotations.
The two key updates are:
-
processBismark()
has been substantially improved by @cemordaunt and theperGroup
argument now considers covariate combinations when choosing the percent of samples per a group for CpG coverage filtering. -
The gene ontology pipes have also been updated to support the latest versions of GREAT and Enrichr.