Update CADD link and warn about licensing requirements

brentp · Aug 9, 2024 · 9e11b27 · 9e11b27
1 parent f27bf94
commit 9e11b27
Showing 1 changed file with 6 additions and 3 deletions.
diff --git a/examples/cadd/README.md b/examples/cadd/README.md
@@ -1,10 +1,13 @@
 This directory contains scripts to convert [CADD](https://cadd.gs.washington.edu/download) to an `echtvar` archive.
 
+**Note that a license is required for commercial use of CADD scores.**
+
 Users can create their own archive like this:
 ```
-wget -c https://kircherlab.bihealth.org/download/CADD/v1.6/GRCh38/whole_genome_SNVs.tsv.gz
-python cadd2vcf.py whole_genome_SNVs.tsv.gz | bcftools view -O b -o cadd.v1.6.bcf
-echtvar encode cadd.v1.6.hg38.zip cadd.json cadd.v1.6.bcf
+# See https://cadd.gs.washington.edu/download for links to older versions, hg19, and US mirrors
+wget -c https://kircherlab.bihealth.org/download/CADD/v1.7/GRCh38/whole_genome_SNVs.tsv.gz
+python cadd2vcf.py whole_genome_SNVs.tsv.gz | bcftools view -O b -o cadd.v1.7.bcf
+echtvar encode cadd.v1.7.hg38.zip cadd.json cadd.v1.7.bcf
 ```
 
 with these `cadd2vcf.py` from this directory and contents for `cadd.json`: